BLAST table : MUP_00320

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q6MZ72_MYCUA
(Q6MZ72)		 
[query] 1 - 14130 (14130)
[subject] 1 - 14130 (14130)
 0.0 28340   100% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
2
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 15 - 12067 (14130)
[subject] 1 - 12088 (12352)
(6 hsp)		 0.0 21310   95% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
3
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 2867 - 8103 (14130)
[subject] 9154 - 14403 (16990)
(44 hsp)		 0.0 8831   91% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
4
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 2867 - 8103 (14130)
[subject] 9154 - 14434 (17019)
(44 hsp)		 0.0 8731   90% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
5
 D7BRD4_STRBB
(D7BRD4)		 
[query] 4744 - 13883 (14130)
[subject] 900 - 9880 (9950)
(23 hsp)		 0.0 6688   45% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
6
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 4892 - 13878 (14130)
[subject] 32 - 8697 (10625)
(26 hsp)		 0.0 6372   44% FscC fscC Streptomyces sp. FR-008
7
 E8S0C5_MICSL
(E8S0C5)		 
[query] 3355 - 11189 (14130)
[subject] 34 - 7719 (9937)
(23 hsp)		 0.0 6302   48% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
8
 D9T6W4_MICAI
(D9T6W4)		 
[query] 3355 - 11189 (14130)
[subject] 34 - 7718 (9936)
(23 hsp)		 0.0 6291   48% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
9
 E0L044_STRVO
(E0L044)		 
[query] 6695 - 13870 (14130)
[subject] 37 - 7143 (7224)
(15 hsp)		 0.0 5630   46% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
10
 A4X8L0_SALTO
(A4X8L0)		 
[query] 6581 - 13871 (14130)
[subject] 58 - 7130 (7210)
(15 hsp)		 0.0 5542   46% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 3195 - 10269 (14130)
[subject] 854 - 7658 (7746)
(24 hsp)		 0.0 5496   46% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
12
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 6587 - 13870 (14130)
[subject] 17 - 7031 (7110)
(14 hsp)		 0.0 5408   46% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
13
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 3353 - 10272 (14130)
[subject] 31 - 6743 (6831)
(14 hsp)		 0.0 5249   46% ScnS1 scnS1 Streptomyces chattanoogensis
14
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 3353 - 10272 (14130)
[subject] 31 - 6709 (6797)
(14 hsp)		 0.0 5139   46% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
15
 B5L6K9_MICCH
(B5L6K9)		 
[query] 6691 - 13936 (14130)
[subject] 36 - 7000 (7007)
(13 hsp)		 0.0 5041   44% Putative type I polyketide synthase Micromonospora chalcea
16
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 3000 - 9902 (14130)
[subject] 2406 - 8902 (9648)
(35 hsp)		 0.0 5038   45% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
17
 Q52V44_9ACTO
(Q52V44)		 
[query] 20 - 6674 (14130)
[subject] 37 - 6663 (6751)
(16 hsp)		 0.0 5036   46% Polyketide synthase type I Streptomyces aizunensis
18
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 3000 - 9902 (14130)
[subject] 2290 - 8782 (9528)
(35 hsp)		 0.0 5035   45% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
19
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 2883 - 9912 (14130)
[subject] 1818 - 8581 (10827)
(38 hsp)		 0.0 5012   45% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
20
 E0KFI9_STRVO
(E0KFI9)		 
[query] 1711 - 7592 (14130)
[subject] 29 - 5913 (8238)
(29 hsp)		 0.0 4991   49% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
21
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 1711 - 7603 (14130)
[subject] 74 - 5922 (10873)
(33 hsp)		 0.0 4877   48% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
22
 Q52V46_9ACTO
(Q52V46)		 
[query] 1711 - 7592 (14130)
[subject] 35 - 5883 (8147)
(28 hsp)		 0.0 4806   49% Polyketide synthase type I Streptomyces aizunensis
23
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 20 - 5792 (14130)
[subject] 36 - 5735 (9498)
(38 hsp)		 0.0 4410   46% ScnS2 scnS2 Streptomyces chattanoogensis
24
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 20 - 5792 (14130)
[subject] 36 - 5741 (9507)
(38 hsp)		 0.0 4324   46% PimS2 protein pimS2 Streptomyces natalensis
25
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 20 - 5792 (14130)
[subject] 41 - 5765 (9550)
(39 hsp)		 0.0 4312   45% FscD fscD Streptomyces sp. FR-008
26
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 20 - 5792 (14130)
[subject] 36 - 5734 (9510)
(42 hsp)		 0.0 4308   45% AmphI amphI Streptomyces nodosus
27
 D9T6W1_MICAI
(D9T6W1)		 
[query] 20 - 5793 (14130)
[subject] 36 - 5696 (6415)
(26 hsp)		 0.0 4279   45% Beta-ketoacyl synthase Micau_2461 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
28
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 4787 - 10272 (14130)
[subject] 911 - 6167 (6241)
(20 hsp)		 0.0 4230   47% Polyketide synthase KijS1 Actinomadura kijaniata
29
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 20 - 5792 (14130)
[subject] 36 - 5779 (9477)
(40 hsp)		 0.0 4228   45% NysI nysI Streptomyces noursei
30
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 6283 - 12071 (14130)
[subject] 5161 - 10833 (10917)
(26 hsp)		 0.0 4172   45% AmphC amphC Streptomyces nodosus
31
 Q93H87_STRAW
(Q93H87)		 
[query] 3195 - 8470 (14130)
[subject] 854 - 5960 (6048)
(24 hsp)		 0.0 4170   47% Modular polyketide synthase pteA1 Streptomyces avermitilis
32
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 6281 - 12067 (14130)
[subject] 4852 - 10140 (10223)
(24 hsp)		 0.0 4155   45% Polyketide synthase rapB Streptomyces hygroscopicus
33
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 20 - 5792 (14130)
[subject] 36 - 5760 (9499)
(40 hsp)		 0.0 4132   45% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
34
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 4773 - 10302 (14130)
[subject] 901 - 6335 (6383)
(22 hsp)		 0.0 4113   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
35
 E0KBI6_STRVO
(E0KBI6)		 
[query] 1816 - 6693 (14130)
[subject] 32 - 4933 (4996)
(18 hsp)		 0.0 4110   48% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
36
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 8493 - 14029 (14130)
[subject] 34 - 5463 (5588)
(13 hsp)		 0.0 4079   45% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
37
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 8136 - 13894 (14130)
[subject] 5223 - 10822 (10876)
(23 hsp)		 0.0 4071   45% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
38
 E0KRC6_STRVO
(E0KRC6)		 
[query] 1350 - 6302 (14130)
[subject] 3986 - 8722 (11118)
(50 hsp)		 0.0 4068   48% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
39
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 8493 - 13937 (14130)
[subject] 35 - 5332 (5339)
(13 hsp)		 0.0 4064   44% Polyketide synthase natB Streptomyces sp. CS
40
 Q52V52_9ACTO
(Q52V52)		 
[query] 6695 - 12072 (14130)
[subject] 35 - 5350 (5432)
(14 hsp)		 0.0 4039   46% Polyketide synthase type I Streptomyces aizunensis
41
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 1329 - 6705 (14130)
[subject] 2043 - 7426 (7480)
(33 hsp)		 0.0 4030   46% Polyketide synthase gfsA Streptomyces graminofaciens
42
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 1709 - 6674 (14130)
[subject] 915 - 5744 (5828)
(29 hsp)		 0.0 3987   47% TamAI Streptomyces sp. 307-9
43
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 6693 - 11666 (14130)
[subject] 18 - 4843 (4894)
(13 hsp)		 0.0 3971   47% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
44
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 8493 - 13876 (14130)
[subject] 35 - 5111 (5176)
(12 hsp)		 0.0 3968   45% ObsB Saccharopolyspora spinosa
45
 Q52V53_9ACTO
(Q52V53)		 
[query] 3353 - 8473 (14130)
[subject] 31 - 5127 (5207)
(14 hsp)		 0.0 3964   46% Polyketide synthase type I Streptomyces aizunensis
46
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 6604 - 12080 (14130)
[subject] 903 - 5980 (6078)
(23 hsp)		 0.0 3964   45% ObsA Saccharopolyspora spinosa
47
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 8492 - 13870 (14130)
[subject] 30 - 5239 (5321)
(13 hsp)		 0.0 3960   45% Polyketide synthase natC Streptomyces sp. CS
48
 F1DI31_9ACTO
(F1DI31)		 
[query] 1709 - 6674 (14130)
[subject] 915 - 5745 (5829)
(29 hsp)		 0.0 3950   47% TrdAI Streptomyces sp. SCSIO1666
49
 B5L6K8_MICCH
(B5L6K8)		 
[query] 4795 - 10272 (14130)
[subject] 921 - 6226 (6305)
(22 hsp)		 0.0 3930   45% Putative type I polyketide synthase Micromonospora chalcea
50
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 1350 - 6274 (14130)
[subject] 4012 - 8798 (11604)
(50 hsp)		 0.0 3898   47% MerC merC Streptomyces violaceoniger
51
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 3352 - 8473 (14130)
[subject] 30 - 5134 (5220)
(14 hsp)		 0.0 3866   46% Type I polyketide synthase hlsC Streptomyces halstedii
52
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 8490 - 13702 (14130)
[subject] 33 - 4960 (6872)
(23 hsp)		 0.0 3860   46% Polyketide synthase KijS2 Actinomadura kijaniata
53
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 1708 - 6674 (14130)
[subject] 946 - 6087 (6171)
(27 hsp)		 0.0 3847   45% Polyketide synthase type I slgA1 Streptomyces lydicus
54
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 6575 - 12083 (14130)
[subject] 6 - 5221 (5260)
(12 hsp)		 0.0 3820   44% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
55
 A8M6C7_SALAI
(A8M6C7)		 
[query] 6694 - 12071 (14130)
[subject] 35 - 5181 (5255)
(12 hsp)		 0.0 3801   44% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
56
 Q93H84_STRAW
(Q93H84)		 
[query] 1347 - 5793 (14130)
[subject] 1068 - 5428 (6145)
(32 hsp)		 0.0 3795   50% Modular polyketide synthase pteA4
SAV416
SAV_416		 Streptomyces avermitilis
57
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 8492 - 14071 (14130)
[subject] 38 - 5330 (5400)
(13 hsp)		 0.0 3782   44% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
58
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 20 - 4872 (14130)
[subject] 40 - 4844 (4928)
(19 hsp)		 0.0 3772   46% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
59
 O52789_AMYMD
(O52789)		 
[query] 8493 - 13875 (14130)
[subject] 44 - 5019 (5069)
(14 hsp)		 0.0 3763   43% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
60
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 8493 - 13875 (14130)
[subject] 35 - 5010 (5060)
(14 hsp)		 0.0 3763   43% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
61
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 8493 - 13875 (14130)
[subject] 35 - 5010 (5060)
(14 hsp)		 0.0 3761   43% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
62
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 6692 - 11192 (14130)
[subject] 32 - 4476 (5214)
(16 hsp)		 0.0 3752   48% Polyketide synthase idmN Streptomyces antibioticus
63
 D9WQ70_9ACTO
(D9WQ70)		 
[query] 2865 - 7592 (14130)
[subject] 321 - 4981 (5483)
(20 hsp)		 0.0 3745   47% Modular polyketide synthase SSOG_05744 Streptomyces himastatinicus ATCC 53653
64
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 1814 - 6674 (14130)
[subject] 33 - 4925 (5006)
(18 hsp)		 0.0 3741   46% Modular polyketide synthase Streptomyces neyagawaensis
65
 C9YYI3_STRSW
(C9YYI3)		 
[query] 1814 - 6674 (14130)
[subject] 33 - 4922 (5001)
(18 hsp)		 0.0 3741   46% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
66
 E0KFI7_STRVO
(E0KFI7)		 
[query] 2865 - 7592 (14130)
[subject] 1292 - 5988 (8538)
(20 hsp)		 0.0 3734   47% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
67
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 8488 - 12989 (14130)
[subject] 29 - 4502 (5232)
(17 hsp)		 0.0 3701   49% Type I polyketide synthase hlsF Streptomyces halstedii
68
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 3352 - 7922 (14130)
[subject] 30 - 4555 (7111)
(29 hsp)		 0.0 3700   48% Type I polyketide synthase hlsB Streptomyces halstedii
69
 D7BRE1_STRBB
(D7BRE1)		 
[query] 1417 - 5792 (14130)
[subject] 48 - 4399 (5139)
(25 hsp)		 0.0 3692   49% Modular polyketide synthase SBI_01983 Streptomyces bingchenggensis (strain BCW-1)
70
 A8J706_9ACTO
(A8J706)		 
[query] 1810 - 6670 (14130)
[subject] 28 - 4862 (5166)
(18 hsp)		 0.0 3687   46% Modular polyketide synthase nemA4 Streptomyces cyaneogriseus subsp. noncyanogenus
71
 E0KBI4_STRVO
(E0KBI4)		 
[query] 1816 - 6110 (14130)
[subject] 33 - 4332 (8275)
(42 hsp)		 0.0 3685   49% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
72
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 6700 - 11711 (14130)
[subject] 41 - 4921 (11096)
(26 hsp)		 0.0 3648   45% NysC nysC Streptomyces noursei
73
 C9YYI1_STRSW
(C9YYI1)		 
[query] 1817 - 6675 (14130)
[subject] 34 - 4891 (4970)
(18 hsp)		 0.0 3640   46% Putative type I polyketide synthase SCAB_83901 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
74
 E0KBI2_STRVO
(E0KBI2)		 
[query] 20 - 4871 (14130)
[subject] 35 - 4847 (4930)
(21 hsp)		 0.0 3640   44% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
75
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 1817 - 6734 (14130)
[subject] 34 - 4940 (4970)
(18 hsp)		 0.0 3628   45% Nodular polyketide synthase Streptomyces neyagawaensis
76
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 4751 - 9534 (14130)
[subject] 873 - 5577 (5582)
(20 hsp)		 0.0 3619   45% Polyketide synthase type I becA Streptomyces sp. DSM 21069
77
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 3266 - 8142 (14130)
[subject] 928 - 5789 (6532)
(32 hsp)		 0.0 3617   46% Polyketide synthase pldAI Streptomyces platensis
78
 F1ADL9_9ACTO
(F1ADL9)		 
[query] 1817 - 6663 (14130)
[subject] 34 - 5050 (5145)
(19 hsp)		 0.0 3593   45% BafAII Streptomyces lohii
79
 D7C2C3_STRBB
(D7C2C3)		 
[query] 20 - 4767 (14130)
[subject] 36 - 4852 (4868)
(19 hsp)		 0.0 3544   45% Modular polyketide synthase pks3-4
SBI_00656		 Streptomyces bingchenggensis (strain BCW-1)
80
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 1816 - 6674 (14130)
[subject] 35 - 4971 (5277)
(18 hsp)		 0.0 3543   45% Modular polyketide synthase meiA4 Streptomyces nanchangensis
81
 E0KBI3_STRVO
(E0KBI3)		 
[query] 1815 - 5792 (14130)
[subject] 33 - 4020 (4750)
(26 hsp)		 0.0 3519   50% 6-methylsalicylic acid synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0198 Streptomyces violaceusniger Tu 4113 2.3.1.165

2.3.1.94
82
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 1368 - 5793 (14130)
[subject] 2518 - 6789 (7968)
(40 hsp)		 0.0 3513   47% Polyketide synthase merC Streptomyces sp. NRRL 30748
83
 E4NJF2_KITSK
(E4NJF2)		 
[query] 1817 - 6674 (14130)
[subject] 34 - 4918 (5004)
(18 hsp)		 0.0 3507   46% Modular polyketide synthase BFAS2 bfmA2
KSE_73450		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
84
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 4894 - 9400 (14130)
[subject] 35 - 4404 (5136)
(16 hsp)		 0.0 3478   47% Polyketide synthase tsnAII Streptomyces longisporoflavus
85
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 4812 - 9160 (14130)
[subject] 902 - 4978 (5113)
(26 hsp)		 0.0 3464   47% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
86
 D5ZU01_9ACTO
(D5ZU01)		 
[query] 1817 - 6684 (14130)
[subject] 62 - 4720 (4790)
(19 hsp)		 0.0 3464   44% Nodular polyketide synthase SSFG_00090 Streptomyces ghanaensis ATCC 14672
87
 A8J6Z6_9ACTO
(A8J6Z6)		 
[query] 1702 - 6670 (14130)
[subject] 940 - 5949 (6043)
(27 hsp)		 0.0 3459   44% Modular polyketide synthase nemA2 Streptomyces cyaneogriseus subsp. noncyanogenus
88
 A0ACH1_STRAM
(A0ACH1)		 
[query] 1427 - 5792 (14130)
[subject] 3198 - 7443 (8154)
(40 hsp)		 0.0 3443   48% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
89
 A8LUX2_SALAI
(A8LUX2)		 
[query] 6601 - 11190 (14130)
[subject] 905 - 5199 (7279)
(30 hsp)		 0.0 3418   46% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
90
 F8JVX1_STRCT
(F8JVX1)		 
[query] 8348 - 12988 (14130)
[subject] 898 - 5399 (6125)
(25 hsp)		 0.0 3413   45% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
91
 E0KCN8_STRVO
(E0KCN8)		 
[query] 1817 - 5797 (14130)
[subject] 35 - 4086 (4810)
(24 hsp)		 0.0 3409   49% 6-deoxyerythronolide-B synthase., 6-methylsalicylic acid synthase StrviDRAFT_0013 Streptomyces violaceusniger Tu 4113 2.3.1.165

2.3.1.94
92
 B1W4J2_STRGG
(B1W4J2)		 
[query] 1811 - 6321 (14130)
[subject] 28 - 4570 (5343)
(28 hsp)		 0.0 3407   45% Putative type-I PKS pks2-2
SGR_6180		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
93
 Q27W58_STRVO
(Q27W58)		 Jump to Niger_00170 
[query] 1817 - 5795 (14130)
[subject] 35 - 4055 (4787)
(25 hsp)		 0.0 3386   48% NigAVII Streptomyces violaceoniger
94
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6694 - 11711 (14130)
[subject] 34 - 4512 (6260)
(29 hsp)		 0.0 3360   44% Polyketide synthase rapC Streptomyces hygroscopicus
95
 A0ACH3_STRAM
(A0ACH3)		 
[query] 18 - 4895 (14130)
[subject] 1023 - 5703 (5771)
(27 hsp)		 0.0 3357   44% Putative type I polyketide synthase SAMR0467 Streptomyces ambofaciens ATCC 23877
96
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 8492 - 13004 (14130)
[subject] 34 - 4273 (8301)
(26 hsp)		 0.0 3352   46% Type I polyketide synthase sfaH Streptomyces flaveolus
97
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 1720 - 6314 (14130)
[subject] 914 - 5370 (6146)
(36 hsp)		 0.0 3350   46% Modular polyketide synthase olmA1
SAV2899
SAV_2899		 Streptomyces avermitilis
98
 D7C2C2_STRBB
(D7C2C2)		 
[query] 1708 - 5798 (14130)
[subject] 43 - 4108 (4821)
(27 hsp)		 0.0 3332   47% Modular polyketide synthase pks3-3
SBI_00655		 Streptomyces bingchenggensis (strain BCW-1)
99
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 1427 - 5981 (14130)
[subject] 3280 - 7841 (8817)
(42 hsp)		 0.0 3331   44% Soraphen polyketide synthase B sorB Sorangium cellulosum
Polyangium cellulosum
100
 F8AWN2_9ACTO
(F8AWN2)		 
[query] 6596 - 11190 (14130)
[subject] 1130 - 5924 (6077)
(29 hsp)		 0.0 3305   44% (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide-B synthase FsymDg_1936 Frankia symbiont of Datisca glomerata 2.3.1.38

2.3.1.94
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q6MZ72_MYCUA
(Q6MZ72)		 
[query] 1 - 14130 (14130)
[subject] 1 - 14130 (14130)
 0.0 28340   100%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
2
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 15 - 12067 (14130)
[subject] 1 - 12088 (12352)
(6 hsp)		 0.0 21310   95%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
3
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 2867 - 8103 (14130)
[subject] 9154 - 14403 (16990)
(44 hsp)		 0.0 8831   91%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
4
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 2867 - 8103 (14130)
[subject] 9154 - 14434 (17019)
(44 hsp)		 0.0 8731   90%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
5
 D7BRD4_STRBB
(D7BRD4)		 
[query] 4744 - 13883 (14130)
[subject] 900 - 9880 (9950)
(23 hsp)		 0.0 6688   45%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 4892 - 13878 (14130)
[subject] 32 - 8697 (10625)
(26 hsp)		 0.0 6372   44%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 3195 - 10269 (14130)
[subject] 854 - 7658 (7746)
(24 hsp)		 0.0 5496   46%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
12
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 6587 - 13870 (14130)
[subject] 17 - 7031 (7110)
(14 hsp)		 0.0 5408   46%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
13
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 3353 - 10272 (14130)
[subject] 31 - 6743 (6831)
(14 hsp)		 0.0 5249   46%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
14
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 3353 - 10272 (14130)
[subject] 31 - 6709 (6797)
(14 hsp)		 0.0 5139   46%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
15
 B5L6K9_MICCH
(B5L6K9)		 
[query] 6691 - 13936 (14130)
[subject] 36 - 7000 (7007)
(13 hsp)		 0.0 5041   44%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
16
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 3000 - 9902 (14130)
[subject] 2406 - 8902 (9648)
(35 hsp)		 0.0 5038   45%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
17
 Q52V44_9ACTO
(Q52V44)		 
[query] 20 - 6674 (14130)
[subject] 37 - 6663 (6751)
(16 hsp)		 0.0 5036   46%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
18
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 3000 - 9902 (14130)
[subject] 2290 - 8782 (9528)
(35 hsp)		 0.0 5035   45%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
19
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 2883 - 9912 (14130)
[subject] 1818 - 8581 (10827)
(38 hsp)		 0.0 5012   45%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
22
 Q52V46_9ACTO
(Q52V46)		 
[query] 1711 - 7592 (14130)
[subject] 35 - 5883 (8147)
(28 hsp)		 0.0 4806   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
23
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 20 - 5792 (14130)
[subject] 36 - 5735 (9498)
(38 hsp)		 0.0 4410   46%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
24
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 20 - 5792 (14130)
[subject] 36 - 5741 (9507)
(38 hsp)		 0.0 4324   46%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
25
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 20 - 5792 (14130)
[subject] 41 - 5765 (9550)
(39 hsp)		 0.0 4312   45%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
26
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 20 - 5792 (14130)
[subject] 36 - 5734 (9510)
(42 hsp)		 0.0 4308   45%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
28
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 4787 - 10272 (14130)
[subject] 911 - 6167 (6241)
(20 hsp)		 0.0 4230   47%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
29
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 20 - 5792 (14130)
[subject] 36 - 5779 (9477)
(40 hsp)		 0.0 4228   45%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
30
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 6283 - 12071 (14130)
[subject] 5161 - 10833 (10917)
(26 hsp)		 0.0 4172   45%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
31
 Q93H87_STRAW
(Q93H87)		 
[query] 3195 - 8470 (14130)
[subject] 854 - 5960 (6048)
(24 hsp)		 0.0 4170   47%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
32
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 6281 - 12067 (14130)
[subject] 4852 - 10140 (10223)
(24 hsp)		 0.0 4155   45%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
33
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 20 - 5792 (14130)
[subject] 36 - 5760 (9499)
(40 hsp)		 0.0 4132   45%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
34
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 4773 - 10302 (14130)
[subject] 901 - 6335 (6383)
(22 hsp)		 0.0 4113   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
36
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 8493 - 14029 (14130)
[subject] 34 - 5463 (5588)
(13 hsp)		 0.0 4079   45%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
37
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 8136 - 13894 (14130)
[subject] 5223 - 10822 (10876)
(23 hsp)		 0.0 4071   45%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
39
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 8493 - 13937 (14130)
[subject] 35 - 5332 (5339)
(13 hsp)		 0.0 4064   44%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
40
 Q52V52_9ACTO
(Q52V52)		 
[query] 6695 - 12072 (14130)
[subject] 35 - 5350 (5432)
(14 hsp)		 0.0 4039   46%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
41
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 1329 - 6705 (14130)
[subject] 2043 - 7426 (7480)
(33 hsp)		 0.0 4030   46%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
42
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 1709 - 6674 (14130)
[subject] 915 - 5744 (5828)
(29 hsp)		 0.0 3987   47%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
44
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 8493 - 13876 (14130)
[subject] 35 - 5111 (5176)
(12 hsp)		 0.0 3968   45%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
45
 Q52V53_9ACTO
(Q52V53)		 
[query] 3353 - 8473 (14130)
[subject] 31 - 5127 (5207)
(14 hsp)		 0.0 3964   46%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
46
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 6604 - 12080 (14130)
[subject] 903 - 5980 (6078)
(23 hsp)		 0.0 3964   45%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
47
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 8492 - 13870 (14130)
[subject] 30 - 5239 (5321)
(13 hsp)		 0.0 3960   45%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
48
 F1DI31_9ACTO
(F1DI31)		 
[query] 1709 - 6674 (14130)
[subject] 915 - 5745 (5829)
(29 hsp)		 0.0 3950   47%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
49
 B5L6K8_MICCH
(B5L6K8)		 
[query] 4795 - 10272 (14130)
[subject] 921 - 6226 (6305)
(22 hsp)		 0.0 3930   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
50
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 1350 - 6274 (14130)
[subject] 4012 - 8798 (11604)
(50 hsp)		 0.0 3898   47%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
52
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 8490 - 13702 (14130)
[subject] 33 - 4960 (6872)
(23 hsp)		 0.0 3860   46%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
53
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 1708 - 6674 (14130)
[subject] 946 - 6087 (6171)
(27 hsp)		 0.0 3847   45%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
56
 Q93H84_STRAW
(Q93H84)		 
[query] 1347 - 5793 (14130)
[subject] 1068 - 5428 (6145)
(32 hsp)		 0.0 3795   50%
Product
Modular polyketide synthase
Gene
pteA4
SAV416
SAV_416
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
57
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 8492 - 14071 (14130)
[subject] 38 - 5330 (5400)
(13 hsp)		 0.0 3782   44%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
58
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 20 - 4872 (14130)
[subject] 40 - 4844 (4928)
(19 hsp)		 0.0 3772   46%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
60
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 8493 - 13875 (14130)
[subject] 35 - 5010 (5060)
(14 hsp)		 0.0 3763   43%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
61
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 8493 - 13875 (14130)
[subject] 35 - 5010 (5060)
(14 hsp)		 0.0 3761   43%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
62
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 6692 - 11192 (14130)
[subject] 32 - 4476 (5214)
(16 hsp)		 0.0 3752   48%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
64
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 1814 - 6674 (14130)
[subject] 33 - 4925 (5006)
(18 hsp)		 0.0 3741   46%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
65
 C9YYI3_STRSW
(C9YYI3)		 
[query] 1814 - 6674 (14130)
[subject] 33 - 4922 (5001)
(18 hsp)		 0.0 3741   46%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
68
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 3352 - 7922 (14130)
[subject] 30 - 4555 (7111)
(29 hsp)		 0.0 3700   48%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
69
 D7BRE1_STRBB
(D7BRE1)		 
[query] 1417 - 5792 (14130)
[subject] 48 - 4399 (5139)
(25 hsp)		 0.0 3692   49%
Product
Modular polyketide synthase
Gene
SBI_01983
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
72
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 6700 - 11711 (14130)
[subject] 41 - 4921 (11096)
(26 hsp)		 0.0 3648   45%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
73
 C9YYI1_STRSW
(C9YYI1)		 
[query] 1817 - 6675 (14130)
[subject] 34 - 4891 (4970)
(18 hsp)		 0.0 3640   46%
Product
Putative type I polyketide synthase
Gene
SCAB_83901
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
75
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 1817 - 6734 (14130)
[subject] 34 - 4940 (4970)
(18 hsp)		 0.0 3628   45%
Product
Nodular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
76
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 4751 - 9534 (14130)
[subject] 873 - 5577 (5582)
(20 hsp)		 0.0 3619   45%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
77
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 3266 - 8142 (14130)
[subject] 928 - 5789 (6532)
(32 hsp)		 0.0 3617   46%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
79
 D7C2C3_STRBB
(D7C2C3)		 
[query] 20 - 4767 (14130)
[subject] 36 - 4852 (4868)
(19 hsp)		 0.0 3544   45%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
80
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 1816 - 6674 (14130)
[subject] 35 - 4971 (5277)
(18 hsp)		 0.0 3543   45%
Product
Modular polyketide synthase
Gene
meiA4
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
82
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 1368 - 5793 (14130)
[subject] 2518 - 6789 (7968)
(40 hsp)		 0.0 3513   47%
Product
Polyketide synthase
Gene
merC
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
83
 E4NJF2_KITSK
(E4NJF2)		 
[query] 1817 - 6674 (14130)
[subject] 34 - 4918 (5004)
(18 hsp)		 0.0 3507   46%
Product
Modular polyketide synthase BFAS2
Gene
bfmA2
KSE_73450
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
88
 A0ACH1_STRAM
(A0ACH1)		 
[query] 1427 - 5792 (14130)
[subject] 3198 - 7443 (8154)
(40 hsp)		 0.0 3443   48%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
92
 B1W4J2_STRGG
(B1W4J2)		 
[query] 1811 - 6321 (14130)
[subject] 28 - 4570 (5343)
(28 hsp)		 0.0 3407   45%
Product
Putative type-I PKS
Gene
pks2-2
SGR_6180
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
93
 Q27W58_STRVO
(Q27W58)		 Jump to Niger_00170 
[query] 1817 - 5795 (14130)
[subject] 35 - 4055 (4787)
(25 hsp)		 0.0 3386   48%
Product
NigAVII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
94
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6694 - 11711 (14130)
[subject] 34 - 4512 (6260)
(29 hsp)		 0.0 3360   44%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
95
 A0ACH3_STRAM
(A0ACH3)		 
[query] 18 - 4895 (14130)
[subject] 1023 - 5703 (5771)
(27 hsp)		 0.0 3357   44%
Product
Putative type I polyketide synthase
Gene
SAMR0467
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
96
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 8492 - 13004 (14130)
[subject] 34 - 4273 (8301)
(26 hsp)		 0.0 3352   46%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
97
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 1720 - 6314 (14130)
[subject] 914 - 5370 (6146)
(36 hsp)		 0.0 3350   46%
Product
Modular polyketide synthase
Gene
olmA1
SAV2899
SAV_2899
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
98
 D7C2C2_STRBB
(D7C2C2)		 
[query] 1708 - 5798 (14130)
[subject] 43 - 4108 (4821)
(27 hsp)		 0.0 3332   47%
Product
Modular polyketide synthase
Gene
pks3-3
SBI_00655
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
99
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 1427 - 5981 (14130)
[subject] 3280 - 7841 (8817)
(42 hsp)		 0.0 3331   44%
Product
Soraphen polyketide synthase B
Gene
sorB
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 7601830 [Medline] 95325306
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995]
2uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
[pubmed all]