BLAST table : Nysta_00150

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q9L4W3_9ACTO
(Q9L4W3)
[query] 1 - 11096 (11096)
[subject] 1 - 11096 (11096)
0.0 21710   100% NysC nysC Streptomyces noursei
2
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1 - 11096 (11096)
[subject] 1 - 10917 (10917)
0.0 15420   75% AmphC amphC Streptomyces nodosus
3
D2CKM4_PSEAH
(D2CKM4)
[query] 1 - 11096 (11096)
[subject] 1 - 10876 (10876)
0.0 13430   69% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
4
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1753 - 9193 (11096)
[subject] 59 - 7196 (7488)
(9 hsp)
0.0 6886   55% ObsC Saccharopolyspora spinosa
5
D7BRD4_STRBB
(D7BRD4)
[query] 5230 - 11096 (11096)
[subject] 4194 - 9950 (9950)
(15 hsp)
0.0 6188   61% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
6
F1CLC1_9ACTO
(F1CLC1)
[query] 5244 - 11096 (11096)
[subject] 1201 - 6831 (6831)
(13 hsp)
0.0 6131   60% ScnS1 scnS1 Streptomyces chattanoogensis
7
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 5244 - 11096 (11096)
[subject] 1187 - 6797 (6797)
(13 hsp)
0.0 6076   60% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
8
E0L044_STRVO
(E0L044)
[query] 5247 - 11081 (11096)
[subject] 1475 - 7209 (7224)
(12 hsp)
0.0 5778   57% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
9
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 5262 - 11012 (11096)
[subject] 1431 - 6945 (10625)
(16 hsp)
0.0 5685   59% FscC fscC Streptomyces sp. FR-008
10
E0L075_STRVO
(E0L075)
[query] 1757 - 7397 (11096)
[subject] 34 - 5714 (5786)
(11 hsp)
0.0 5683   57% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
11
D7C2B8_STRBB
(D7C2B8)
[query] 2986 - 8811 (11096)
[subject] 1057 - 6742 (7498)
(21 hsp)
0.0 5643   57% Type I modular polyketide synthase pks3-2
SBI_00651
Streptomyces bingchenggensis (strain BCW-1)
12
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 1750 - 7402 (11096)
[subject] 32 - 5573 (5644)
(9 hsp)
0.0 5449   56% AmphJ amphJ Streptomyces nodosus
13
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 29 - 6504 (11096)
[subject] 3796 - 10159 (10827)
(31 hsp)
0.0 5395   51% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
14
Q82QT4_STRAW
(Q82QT4)
[query] 5244 - 11096 (11096)
[subject] 2173 - 7746 (7746)
(20 hsp)
0.0 5227   54% Modular polyketide synthase pteA1
SAV419
SAV_419
Streptomyces avermitilis
15
Q52V52_9ACTO
(Q52V52)
[query] 5624 - 11094 (11096)
[subject] 35 - 5430 (5432)
(4 hsp)
0.0 5163   56% Polyketide synthase type I Streptomyces aizunensis
16
D9T6W4_MICAI
(D9T6W4)
[query] 5244 - 11023 (11096)
[subject] 1213 - 6830 (9936)
(27 hsp)
0.0 5071   54% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
17
E8S0C5_MICSL
(E8S0C5)
[query] 5244 - 11023 (11096)
[subject] 1213 - 6830 (9937)
(27 hsp)
0.0 5043   54% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
18
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 3389 - 9193 (11096)
[subject] 23 - 5744 (5826)
(11 hsp)
0.0 5022   52% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
19
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 4799 - 11094 (11096)
[subject] 4461 - 10219 (10223)
(13 hsp)
0.0 4926   49% Polyketide synthase rapB Streptomyces hygroscopicus
20
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1755 - 7388 (11096)
[subject] 33 - 5476 (5770)
(11 hsp)
0.0 4840   52% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
21
Q6JHN7_9PSEU
(Q6JHN7)
[query] 5622 - 11092 (11096)
[subject] 34 - 5176 (5176)
(11 hsp)
0.0 4728   52% ObsB Saccharopolyspora spinosa
22
B4VDY6_9ACTO
(B4VDY6)
[query] 5623 - 10571 (11096)
[subject] 19 - 4843 (4894)
(7 hsp)
0.0 4720   55% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
23
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 1285 - 7389 (11096)
[subject] 2824 - 8487 (8563)
(18 hsp)
0.0 4696   49% Polyketide synthase rapA Streptomyces hygroscopicus
24
A4X8L0_SALTO
(A4X8L0)
[query] 5263 - 11093 (11096)
[subject] 1549 - 7206 (7210)
(11 hsp)
0.0 4690   50% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
25
C6WNW1_ACTMD
(C6WNW1)
[query] 5262 - 11093 (11096)
[subject] 1523 - 7106 (7110)
(8 hsp)
0.0 4679   51% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
26
D9VEY7_9ACTO
(D9VEY7)
[query] 5509 - 11041 (11096)
[subject] 13 - 5244 (5260)
(9 hsp)
0.0 4672   52% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
27
C3VLY1_9ACTO
(C3VLY1)
[query] 5489 - 11096 (11096)
[subject] 891 - 6383 (6383)
(14 hsp)
0.0 4630   49% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
28
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 5623 - 11014 (11096)
[subject] 34 - 5292 (5588)
(5 hsp)
0.0 4611   51% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
29
A1YAN0_AMYOR
(A1YAN0)
[query] 4 - 4911 (11096)
[subject] 3 - 4658 (5099)
(9 hsp)
0.0 4551   55% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
30
E3JBU2_FRASU
(E3JBU2)
[query] 3003 - 9199 (11096)
[subject] 1294 - 7611 (7679)
(10 hsp)
0.0 4522   47% Acyl transferase FraEuI1c_4253 Frankia sp. (strain EuI1c)
31
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 3123 - 8279 (11096)
[subject] 1735 - 6685 (7620)
(26 hsp)
0.0 4500   53% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
32
D9T6W3_MICAI
(D9T6W3)
[query] 3108 - 8279 (11096)
[subject] 1718 - 6799 (7520)
(25 hsp)
0.0 4497   53% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
33
C6ZCS0_9ACTO
(C6ZCS0)
[query] 3123 - 8279 (11096)
[subject] 1693 - 6641 (7576)
(26 hsp)
0.0 4495   53% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
34
E8S0C6_MICSL
(E8S0C6)
[query] 3108 - 8279 (11096)
[subject] 1718 - 6799 (7520)
(25 hsp)
0.0 4484   53% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
35
C6WNV0_ACTMD
(C6WNV0)
[query] 4 - 4902 (11096)
[subject] 8 - 4733 (5400)
(11 hsp)
0.0 4471   55% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
36
Q6JHN8_9PSEU
(Q6JHN8)
[query] 5529 - 11013 (11096)
[subject] 901 - 5975 (6078)
(13 hsp)
0.0 4467   51% ObsA Saccharopolyspora spinosa
37
B5L6K9_MICCH
(B5L6K9)
[query] 5246 - 11009 (11096)
[subject] 1376 - 6930 (7007)
(11 hsp)
0.0 4379   48% Putative type I polyketide synthase Micromonospora chalcea
38
F8QPF9_9ACTO
(F8QPF9)
[query] 5623 - 11095 (11096)
[subject] 35 - 5338 (5339)
(5 hsp)
0.0 4306   49% Polyketide synthase natB Streptomyces sp. CS
39
F8QPG0_9ACTO
(F8QPG0)
[query] 1 - 4736 (11096)
[subject] 1 - 4772 (5321)
(13 hsp)
0.0 4175   53% Polyketide synthase natC Streptomyces sp. CS
40
C3VLV4_9ACTO
(C3VLV4)
[query] 5513 - 10235 (11096)
[subject] 916 - 5575 (5582)
(12 hsp)
0.0 4174   50% Polyketide synthase type I becA Streptomyces sp. DSM 21069
41
E8WEN5_STRFA
(E8WEN5)
[query] 3 - 4911 (11096)
[subject] 2 - 4715 (5156)
(8 hsp)
0.0 4159   52% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
42
D7CC08_STRBB
(D7CC08)
[query] 1757 - 6520 (11096)
[subject] 34 - 4790 (5530)
(18 hsp)
0.0 4076   52% Putative type I polyketide synthase pks5-2
SBI_01382
Streptomyces bingchenggensis (strain BCW-1)
43
D7P611_CHOCO
(D7P611)
[query] 478 - 5602 (11096)
[subject] 989 - 6159 (6255)
(18 hsp)
0.0 4026   49% TugA tugA Chondromyces crocatus
44
B5M9K9_STRLS
(B5M9K9)
Jump to Lasal2_00170
[query] 1757 - 6513 (11096)
[subject] 34 - 4744 (5469)
(18 hsp)
0.0 4020   51% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
45
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 1764 - 6513 (11096)
[subject] 1 - 4704 (5429)
(18 hsp)
0.0 4006   51% Putative polyketide synthase lsd12 Streptomyces lasaliensis
46
F8JUL0_STRCT
(F8JUL0)
[query] 35 - 4508 (11096)
[subject] 1030 - 5432 (5950)
(23 hsp)
0.0 3969   54% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
47
B3TMQ7_9ACTO
(B3TMQ7)
[query] 1 - 4663 (11096)
[subject] 1 - 4607 (6872)
(21 hsp)
0.0 3949   52% Polyketide synthase KijS2 Actinomadura kijaniata
48
A8M6C7_SALAI
(A8M6C7)
[query] 5623 - 11012 (11096)
[subject] 35 - 5181 (5255)
(9 hsp)
0.0 3935   48% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
49
B5L6K8_MICCH
(B5L6K8)
[query] 5522 - 11094 (11096)
[subject] 921 - 6303 (6305)
(14 hsp)
0.0 3896   45% Putative type I polyketide synthase Micromonospora chalcea
50
C5HV16_STRAT
(C5HV16)
Jump to Indano_00180
[query] 6 - 4371 (11096)
[subject] 5 - 4473 (5214)
(14 hsp)
0.0 3882   53% Polyketide synthase idmN Streptomyces antibioticus
51
Q52V50_9ACTO
(Q52V50)
[query] 7034 - 11096 (11096)
[subject] 3549 - 7510 (7510)
(10 hsp)
0.0 3879   56% Polyketide synthase type I Streptomyces aizunensis
52
Q0PCZ9_STRHA
(Q0PCZ9)
Jump to Halsto_00060
[query] 4 - 4371 (11096)
[subject] 3 - 4501 (5232)
(14 hsp)
0.0 3877   52% Type I polyketide synthase hlsF Streptomyces halstedii
53
B3TMQ8_9ACTO
(B3TMQ8)
[query] 33 - 4911 (11096)
[subject] 1020 - 5797 (6241)
(17 hsp)
0.0 3870   50% Polyketide synthase KijS1 Actinomadura kijaniata
54
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 3 - 4371 (11096)
[subject] 6 - 4550 (7026)
(14 hsp)
0.0 3844   52% Polyketide synthase pldAII Streptomyces platensis
55
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 35 - 4661 (11096)
[subject] 4257 - 8728 (9648)
(35 hsp)
0.0 3837   51% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
56
C6ZCS1_9ACTO
(C6ZCS1)
[query] 35 - 4661 (11096)
[subject] 4141 - 8608 (9528)
(35 hsp)
0.0 3834   51% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
57
F8JVX1_STRCT
(F8JVX1)
[query] 5523 - 10098 (11096)
[subject] 945 - 5400 (6125)
(18 hsp)
0.0 3812   50% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
58
D3U9Y8_9ACTO
(D3U9Y8)
[query] 1 - 4371 (11096)
[subject] 1 - 4257 (8301)
(20 hsp)
0.0 3797   55% Type I polyketide synthase sfaH Streptomyces flaveolus
59
B4VB11_9ACTO
(B4VB11)
[query] 7097 - 11060 (11096)
[subject] 5 - 3890 (3928)
(6 hsp)
0.0 3761   57% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
60
Q0R4M5_STRAT
(Q0R4M5)
Jump to Chth_00290
[query] 4799 - 9193 (11096)
[subject] 1293 - 5630 (5718)
(8 hsp)
0.0 3760   51% ChlA3 Streptomyces antibioticus
61
Q52V53_9ACTO
(Q52V53)
[query] 5244 - 9193 (11096)
[subject] 1217 - 5127 (5207)
(10 hsp)
0.0 3747   55% Polyketide synthase type I Streptomyces aizunensis
62
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 4688 (11096)
[subject] 5 - 4355 (6260)
(21 hsp)
0.0 3720   49% Polyketide synthase rapC Streptomyces hygroscopicus
63
D7F1M0_9ACTO
(D7F1M0)
[query] 6 - 4371 (11096)
[subject] 7 - 4393 (5136)
(14 hsp)
0.0 3704   51% Polyketide synthase tsnAII Streptomyces longisporoflavus
64
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 4698 (11096)
[subject] 1 - 4508 (5060)
(12 hsp)
0.0 3682   49% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
65
B6ZIR2_STRPT
(B6ZIR2)
Jump to Pladi_00010
[query] 1187 - 5602 (11096)
[subject] 1966 - 6450 (6532)
(23 hsp)
0.0 3682   51% Polyketide synthase pldAI Streptomyces platensis
66
O52789_AMYMD
(O52789)
[query] 1 - 4698 (11096)
[subject] 10 - 4517 (5069)
(12 hsp)
0.0 3681   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
67
A8LUX2_SALAI
(A8LUX2)
[query] 35 - 4371 (11096)
[subject] 991 - 5198 (7279)
(30 hsp)
0.0 3679   52% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
68
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 4698 (11096)
[subject] 1 - 4508 (5060)
(12 hsp)
0.0 3679   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
69
D6B4Q9_9ACTO
(D6B4Q9)
[query] 6933 - 11000 (11096)
[subject] 113 - 3996 (5945)
(13 hsp)
0.0 3645   55% Polyketide synthase SSHG_00090 Streptomyces albus J1074
70
F8AWN2_9ACTO
(F8AWN2)
[query] 35 - 4373 (11096)
[subject] 1235 - 5925 (6077)
(32 hsp)
0.0 3600   50% (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide-B synthase FsymDg_1936 Frankia symbiont of Datisca glomerata 2.3.1.38

2.3.1.94
71
Q93H87_STRAW
(Q93H87)
[query] 6947 - 11096 (11096)
[subject] 2096 - 6048 (6048)
(21 hsp)
0.0 3585   53% Modular polyketide synthase pteA1 Streptomyces avermitilis
72
Q52V49_9ACTO
(Q52V49)
[query] 7408 - 11012 (11096)
[subject] 33 - 3577 (3872)
(8 hsp)
0.0 3578   58% Polyketide synthase type I Streptomyces aizunensis
73
D9W5N3_9ACTO
(D9W5N3)
[query] 1643 - 5601 (11096)
[subject] 490 - 4401 (4488)
(17 hsp)
0.0 3571   54% Lasalocid modular polyketide synthase SSNG_07463 Streptomyces sp. C
74
Q0R4M7_STRAT
(Q0R4M7)
Jump to Chth_00270
[query] 1724 - 5608 (11096)
[subject] 11 - 3881 (3955)
(10 hsp)
0.0 3569   53% ChlA2 Streptomyces antibioticus
75
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 4805 - 9193 (11096)
[subject] 1354 - 5734 (5822)
(8 hsp)
0.0 3568   50% Modular polyketide synthase meiA3 Streptomyces nanchangensis
76
D9VBL5_9ACTO
(D9VBL5)
[query] 37 - 4144 (11096)
[subject] 984 - 4974 (5113)
(22 hsp)
0.0 3553   52% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
77
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 35 - 4688 (11096)
[subject] 6694 - 11522 (14130)
(32 hsp)
0.0 3520   46% Type I modular polyketide synthase mlsB
MUP032c
Mycobacterium ulcerans (strain Agy99)
78
D7F1M1_9ACTO
(D7F1M1)
[query] 4786 - 9193 (11096)
[subject] 1264 - 5547 (5630)
(12 hsp)
0.0 3496   48% Polyketide synthase tsnAIII Streptomyces longisporoflavus
79
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 3051 - 7389 (11096)
[subject] 2868 - 7098 (7178)
(20 hsp)
0.0 3491   50% MerB merB Streptomyces violaceoniger
80
B6CLY1_9MYCO
(B6CLY1)
[query] 35 - 4688 (11096)
[subject] 6697 - 11543 (12352)
(29 hsp)
0.0 3488   46% Type I modular polyketide synthase, MlsB mlsB
MULP_051
Mycobacterium liflandii 128FXT
81
Q0PD02_STRHA
(Q0PD02)
Jump to Halsto_00030
[query] 6946 - 11096 (11096)
[subject] 1123 - 5219 (5220)
(12 hsp)
0.0 3464   51% Type I polyketide synthase hlsC Streptomyces halstedii
82
Q1WEK8_9ACTO
(Q1WEK8)
[query] 3051 - 7431 (11096)
[subject] 2823 - 7072 (7102)
(21 hsp)
0.0 3450   49% Polyketide synthase merB Streptomyces sp. NRRL 30748
83
B5M9K8_STRLS
(B5M9K8)
Jump to Lasal2_00160
[query] 1656 - 5609 (11096)
[subject] 953 - 4912 (4986)
(18 hsp)
0.0 3434   52% Lasalocid modular polyketide synthase lasAI Streptomyces lasaliensis
84
B6ZK64_STRLS
(B6ZK64)
Jump to Lasal_00130
[query] 1656 - 5609 (11096)
[subject] 860 - 4819 (4893)
(18 hsp)
0.0 3434   52% Putative polyketide synthase lsd11 Streptomyces lasaliensis
85
C6K7D8_9ACTO
(C6K7D8)
[query] 35 - 4687 (11096)
[subject] 3150 - 7393 (7938)
(20 hsp)
0.0 3424   48% Polyketide synthase rapA Actinoplanes sp. N902-109
86
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 37 - 4688 (11096)
[subject] 20 - 4858 (16990)
(37 hsp)
0.0 3410   45% Type I modular polyketide synthase mlsA1
MUP040c
Mycobacterium ulcerans (strain Agy99)
87
C0Z477_STRVN
(C0Z477)
[query] 30 - 4374 (11096)
[subject] 1056 - 5374 (6130)
(18 hsp)
0.0 3398   50% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
88
B6CLY8_9MYCO
(B6CLY8)
[query] 37 - 4688 (11096)
[subject] 20 - 4856 (17019)
(36 hsp)
0.0 3392   45% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065
Mycobacterium liflandii 128FXT
89
Q30CS0_STRAU
(Q30CS0)
Jump to Alip_00150
[query] 5623 - 9194 (11096)
[subject] 34 - 3535 (3612)
(7 hsp)
0.0 3392   54% LipPks3 lipPks3 Streptomyces aureofaciens
90
Q0RIF5_FRAAA
(Q0RIF5)
[query] 35 - 4909 (11096)
[subject] 1012 - 5932 (6432)
(14 hsp)
0.0 3377   46% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
91
E0KBI0_STRVO
(E0KBI0)
[query] 1752 - 5601 (11096)
[subject] 32 - 3858 (3955)
(11 hsp)
0.0 3347   51% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
92
D7CC07_STRBB
(D7CC07)
[query] 1646 - 5613 (11096)
[subject] 941 - 4903 (4979)
(17 hsp)
0.0 3343   52% Putative type I polyketide synthase pks5-1
SBI_01381
Streptomyces bingchenggensis (strain BCW-1)
93
D7F1N2_9ACTO
(D7F1N2)
[query] 1643 - 5601 (11096)
[subject] 975 - 4953 (5029)
(16 hsp)
0.0 3336   51% Polyketide synthase tsnAI Streptomyces longisporoflavus
94
Q9KIE0_STRHY
(Q9KIE0)
Jump to Asco_00140
[query] 35 - 4661 (11096)
[subject] 2760 - 7091 (7525)
(21 hsp)
0.0 3330   48% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
95
Q0QMN5_9ACTO
(Q0QMN5)
[query] 4096 - 8278 (11096)
[subject] 681 - 4697 (5393)
(22 hsp)
0.0 3324   51% Polyketide synthase type I Streptomyces sp. Eco86
96
E0KRC6_STRVO
(E0KRC6)
[query] 3013 - 7411 (11096)
[subject] 6908 - 11088 (11118)
(45 hsp)
0.0 3321   49% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
97
D9WB05_9ACTO
(D9WB05)
[query] 3 - 2730 (11096)
[subject] 2 - 2718 (2718)
(7 hsp)
0.0 3320   65% Modular polyketide synthase SSOG_00511 Streptomyces himastatinicus ATCC 53653
98
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 2932 - 7413 (11096)
[subject] 6840 - 11231 (11604)
(48 hsp)
0.0 3317   47% MerC merC Streptomyces violaceoniger
99
A1YAM6_AMYOR
(A1YAM6)
[query] 1658 - 5612 (11096)
[subject] 34 - 3771 (3834)
(13 hsp)
0.0 3305   53% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
100
Q0R4M3_STRAT
(Q0R4M3)
Jump to Chth_00310
[query] 3474 - 7388 (11096)
[subject] 4 - 3861 (3936)
(10 hsp)
0.0 3303   51% ChlA5 Streptomyces antibioticus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9L4W3_9ACTO
(Q9L4W3)
[query] 1 - 11096 (11096)
[subject] 1 - 11096 (11096)
0.0 21710   100%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
2
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1 - 11096 (11096)
[subject] 1 - 10917 (10917)
0.0 15420   75%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
3
D2CKM4_PSEAH
(D2CKM4)
[query] 1 - 11096 (11096)
[subject] 1 - 10876 (10876)
0.0 13430   69%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
4
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1753 - 9193 (11096)
[subject] 59 - 7196 (7488)
(9 hsp)
0.0 6886   55%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
5
D7BRD4_STRBB
(D7BRD4)
[query] 5230 - 11096 (11096)
[subject] 4194 - 9950 (9950)
(15 hsp)
0.0 6188   61%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
F1CLC1_9ACTO
(F1CLC1)
[query] 5244 - 11096 (11096)
[subject] 1201 - 6831 (6831)
(13 hsp)
0.0 6131   60%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
7
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 5244 - 11096 (11096)
[subject] 1187 - 6797 (6797)
(13 hsp)
0.0 6076   60%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
9
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 5262 - 11012 (11096)
[subject] 1431 - 6945 (10625)
(16 hsp)
0.0 5685   59%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
11
D7C2B8_STRBB
(D7C2B8)
[query] 2986 - 8811 (11096)
[subject] 1057 - 6742 (7498)
(21 hsp)
0.0 5643   57%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
12
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 1750 - 7402 (11096)
[subject] 32 - 5573 (5644)
(9 hsp)
0.0 5449   56%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
13
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 29 - 6504 (11096)
[subject] 3796 - 10159 (10827)
(31 hsp)
0.0 5395   51%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
14
Q82QT4_STRAW
(Q82QT4)
[query] 5244 - 11096 (11096)
[subject] 2173 - 7746 (7746)
(20 hsp)
0.0 5227   54%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
15
Q52V52_9ACTO
(Q52V52)
[query] 5624 - 11094 (11096)
[subject] 35 - 5430 (5432)
(4 hsp)
0.0 5163   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
18
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 3389 - 9193 (11096)
[subject] 23 - 5744 (5826)
(11 hsp)
0.0 5022   52%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
19
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 4799 - 11094 (11096)
[subject] 4461 - 10219 (10223)
(13 hsp)
0.0 4926   49%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
20
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1755 - 7388 (11096)
[subject] 33 - 5476 (5770)
(11 hsp)
0.0 4840   52%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
21
Q6JHN7_9PSEU
(Q6JHN7)
[query] 5622 - 11092 (11096)
[subject] 34 - 5176 (5176)
(11 hsp)
0.0 4728   52%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
23
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 1285 - 7389 (11096)
[subject] 2824 - 8487 (8563)
(18 hsp)
0.0 4696   49%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
25
C6WNW1_ACTMD
(C6WNW1)
[query] 5262 - 11093 (11096)
[subject] 1523 - 7106 (7110)
(8 hsp)
0.0 4679   51%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
27
C3VLY1_9ACTO
(C3VLY1)
[query] 5489 - 11096 (11096)
[subject] 891 - 6383 (6383)
(14 hsp)
0.0 4630   49%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
28
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 5623 - 11014 (11096)
[subject] 34 - 5292 (5588)
(5 hsp)
0.0 4611   51%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
29
A1YAN0_AMYOR
(A1YAN0)
[query] 4 - 4911 (11096)
[subject] 3 - 4658 (5099)
(9 hsp)
0.0 4551   55%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
31
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 3123 - 8279 (11096)
[subject] 1735 - 6685 (7620)
(26 hsp)
0.0 4500   53%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
33
C6ZCS0_9ACTO
(C6ZCS0)
[query] 3123 - 8279 (11096)
[subject] 1693 - 6641 (7576)
(26 hsp)
0.0 4495   53%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
35
C6WNV0_ACTMD
(C6WNV0)
[query] 4 - 4902 (11096)
[subject] 8 - 4733 (5400)
(11 hsp)
0.0 4471   55%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
36
Q6JHN8_9PSEU
(Q6JHN8)
[query] 5529 - 11013 (11096)
[subject] 901 - 5975 (6078)
(13 hsp)
0.0 4467   51%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
37
B5L6K9_MICCH
(B5L6K9)
[query] 5246 - 11009 (11096)
[subject] 1376 - 6930 (7007)
(11 hsp)
0.0 4379   48%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
38
F8QPF9_9ACTO
(F8QPF9)
[query] 5623 - 11095 (11096)
[subject] 35 - 5338 (5339)
(5 hsp)
0.0 4306   49%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
39
F8QPG0_9ACTO
(F8QPG0)
[query] 1 - 4736 (11096)
[subject] 1 - 4772 (5321)
(13 hsp)
0.0 4175   53%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
40
C3VLV4_9ACTO
(C3VLV4)
[query] 5513 - 10235 (11096)
[subject] 916 - 5575 (5582)
(12 hsp)
0.0 4174   50%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
42
D7CC08_STRBB
(D7CC08)
[query] 1757 - 6520 (11096)
[subject] 34 - 4790 (5530)
(18 hsp)
0.0 4076   52%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
43
D7P611_CHOCO
(D7P611)
[query] 478 - 5602 (11096)
[subject] 989 - 6159 (6255)
(18 hsp)
0.0 4026   49%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
45
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 1764 - 6513 (11096)
[subject] 1 - 4704 (5429)
(18 hsp)
0.0 4006   51%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
47
B3TMQ7_9ACTO
(B3TMQ7)
[query] 1 - 4663 (11096)
[subject] 1 - 4607 (6872)
(21 hsp)
0.0 3949   52%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
49
B5L6K8_MICCH
(B5L6K8)
[query] 5522 - 11094 (11096)
[subject] 921 - 6303 (6305)
(14 hsp)
0.0 3896   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
50
C5HV16_STRAT
(C5HV16)
Jump to Indano_00180
[query] 6 - 4371 (11096)
[subject] 5 - 4473 (5214)
(14 hsp)
0.0 3882   53%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
51
Q52V50_9ACTO
(Q52V50)
[query] 7034 - 11096 (11096)
[subject] 3549 - 7510 (7510)
(10 hsp)
0.0 3879   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
53
B3TMQ8_9ACTO
(B3TMQ8)
[query] 33 - 4911 (11096)
[subject] 1020 - 5797 (6241)
(17 hsp)
0.0 3870   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
54
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 3 - 4371 (11096)
[subject] 6 - 4550 (7026)
(14 hsp)
0.0 3844   52%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
55
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 35 - 4661 (11096)
[subject] 4257 - 8728 (9648)
(35 hsp)
0.0 3837   51%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
56
C6ZCS1_9ACTO
(C6ZCS1)
[query] 35 - 4661 (11096)
[subject] 4141 - 8608 (9528)
(35 hsp)
0.0 3834   51%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
58
D3U9Y8_9ACTO
(D3U9Y8)
[query] 1 - 4371 (11096)
[subject] 1 - 4257 (8301)
(20 hsp)
0.0 3797   55%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
60
Q0R4M5_STRAT
(Q0R4M5)
Jump to Chth_00290
[query] 4799 - 9193 (11096)
[subject] 1293 - 5630 (5718)
(8 hsp)
0.0 3760   51%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
61
Q52V53_9ACTO
(Q52V53)
[query] 5244 - 9193 (11096)
[subject] 1217 - 5127 (5207)
(10 hsp)
0.0 3747   55%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
62
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 4688 (11096)
[subject] 5 - 4355 (6260)
(21 hsp)
0.0 3720   49%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
64
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 4698 (11096)
[subject] 1 - 4508 (5060)
(12 hsp)
0.0 3682   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
65
B6ZIR2_STRPT
(B6ZIR2)
Jump to Pladi_00010
[query] 1187 - 5602 (11096)
[subject] 1966 - 6450 (6532)
(23 hsp)
0.0 3682   51%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
68
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 4698 (11096)
[subject] 1 - 4508 (5060)
(12 hsp)
0.0 3679   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
71
Q93H87_STRAW
(Q93H87)
[query] 6947 - 11096 (11096)
[subject] 2096 - 6048 (6048)
(21 hsp)
0.0 3585   53%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
72
Q52V49_9ACTO
(Q52V49)
[query] 7408 - 11012 (11096)
[subject] 33 - 3577 (3872)
(8 hsp)
0.0 3578   58%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
74
Q0R4M7_STRAT
(Q0R4M7)
Jump to Chth_00270
[query] 1724 - 5608 (11096)
[subject] 11 - 3881 (3955)
(10 hsp)
0.0 3569   53%
Product
ChlA2
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
75
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 4805 - 9193 (11096)
[subject] 1354 - 5734 (5822)
(8 hsp)
0.0 3568   50%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
77
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 35 - 4688 (11096)
[subject] 6694 - 11522 (14130)
(32 hsp)
0.0 3520   46%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
79
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 3051 - 7389 (11096)
[subject] 2868 - 7098 (7178)
(20 hsp)
0.0 3491   50%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
80
B6CLY1_9MYCO
(B6CLY1)
[query] 35 - 4688 (11096)
[subject] 6697 - 11543 (12352)
(29 hsp)
0.0 3488   46%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
82
Q1WEK8_9ACTO
(Q1WEK8)
[query] 3051 - 7431 (11096)
[subject] 2823 - 7072 (7102)
(21 hsp)
0.0 3450   49%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
84
B6ZK64_STRLS
(B6ZK64)
Jump to Lasal_00130
[query] 1656 - 5609 (11096)
[subject] 860 - 4819 (4893)
(18 hsp)
0.0 3434   52%
Product
Putative polyketide synthase
Gene
lsd11
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
86
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 37 - 4688 (11096)
[subject] 20 - 4858 (16990)
(37 hsp)
0.0 3410   45%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
88
B6CLY8_9MYCO
(B6CLY8)
[query] 37 - 4688 (11096)
[subject] 20 - 4856 (17019)
(36 hsp)
0.0 3392   45%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
89
Q30CS0_STRAU
(Q30CS0)
Jump to Alip_00150
[query] 5623 - 9194 (11096)
[subject] 34 - 3535 (3612)
(7 hsp)
0.0 3392   54%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
90
Q0RIF5_FRAAA
(Q0RIF5)
[query] 35 - 4909 (11096)
[subject] 1012 - 5932 (6432)
(14 hsp)
0.0 3377   46%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
92
D7CC07_STRBB
(D7CC07)
[query] 1646 - 5613 (11096)
[subject] 941 - 4903 (4979)
(17 hsp)
0.0 3343   52%
Product
Putative type I polyketide synthase
Gene
pks5-1
SBI_01381
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
94
Q9KIE0_STRHY
(Q9KIE0)
Jump to Asco_00140
[query] 35 - 4661 (11096)
[subject] 2760 - 7091 (7525)
(21 hsp)
0.0 3330   48%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
95
Q0QMN5_9ACTO
(Q0QMN5)
[query] 4096 - 8278 (11096)
[subject] 681 - 4697 (5393)
(22 hsp)
0.0 3324   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces sp. Eco86
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
98
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 2932 - 7413 (11096)
[subject] 6840 - 11231 (11604)
(48 hsp)
0.0 3317   47%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
99
A1YAM6_AMYOR
(A1YAM6)
[query] 1658 - 5612 (11096)
[subject] 34 - 3771 (3834)
(13 hsp)
0.0 3305   53%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
100
Q0R4M3_STRAT
(Q0R4M3)
Jump to Chth_00310
[query] 3474 - 7388 (11096)
[subject] 4 - 3861 (3936)
(10 hsp)
0.0 3303   51%
Product
ChlA5
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]