BLAST table : Pikro_00060

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q9ZGI2_9ACTO
(Q9ZGI2)
[query] 1 - 1346 (1346)
[subject] 1 - 1346 (1346)
0.0 2678   100% Type I polyketide synthase PikAIV pikAIV Streptomyces venezuelae
2
Q9ZGI4_9ACTO
(Q9ZGI4)
Jump to Pikro_00040
[query] 2 - 911 (1346)
[subject] 3 - 920 (3739)
(4 hsp)
0.0 1345   75% Type I polyketide synthase PikAII pikAII Streptomyces venezuelae
3
Q9ZGI3_9ACTO
(Q9ZGI3)
Jump to Pikro_00050
[query] 1 - 913 (1346)
[subject] 1 - 912 (1562)
(2 hsp)
0.0 1336   74% Type I polyketide synthase PikAIII pikAIII Streptomyces venezuelae
4
Q9ZGI5_9ACTO
(Q9ZGI5)
Jump to Pikro_00030
[query] 35 - 920 (1346)
[subject] 1109 - 1999 (4613)
(5 hsp)
0.0 1244   72% Type I polyketide synthase PikAI pikAI Streptomyces venezuelae
5
B6ZK66_STRLS
(B6ZK66)
Jump to Lasal_00150
[query] 1 - 1030 (1346)
[subject] 6 - 1042 (1113)
0.0 1008   54% Putative polyketide synthase lsd13 Streptomyces lasaliensis
6
D9WG07_9ACTO
(D9WG07)
[query] 35 - 919 (1346)
[subject] 2023 - 2907 (3668)
(5 hsp)
0.0 1008   60% Modular polyketide synthase SSOG_02937 Streptomyces himastatinicus ATCC 53653
7
B5M9L0_STRLS
(B5M9L0)
Jump to Lasal2_00180
[query] 1 - 1030 (1346)
[subject] 1 - 1037 (1108)
0.0 1007   54% Lasalocid modular polyketide synthase lasAIII Streptomyces lasaliensis
8
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 909 (1346)
[subject] 1 - 908 (5060)
(6 hsp)
0.0 1001   59% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
9
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 909 (1346)
[subject] 1 - 908 (5060)
(6 hsp)
0.0 1001   59% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
10
O52789_AMYMD
(O52789)
[query] 1 - 909 (1346)
[subject] 10 - 917 (5069)
(6 hsp)
0.0 1001   59% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
11
D9WQ82_9ACTO
(D9WQ82)
[query] 1 - 905 (1346)
[subject] 1 - 917 (3199)
(4 hsp)
0.0 997   57% Erythronolide synthase, modules 1 and 2 SSOG_05756 Streptomyces himastatinicus ATCC 53653
12
E0KBI2_STRVO
(E0KBI2)
[query] 35 - 923 (1346)
[subject] 1760 - 2661 (4930)
(6 hsp)
0.0 989   58% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
13
D1GLV9_9ACTO
(D1GLV9)
Jump to Strply_00310
[query] 35 - 918 (1346)
[subject] 4200 - 5099 (6171)
(7 hsp)
0.0 987   59% Polyketide synthase type I slgA1 Streptomyces lydicus
14
Q331Q2_9ACTO
(Q331Q2)
[query] 1 - 1338 (1346)
[subject] 1 - 1357 (1357)
0.0 984   45% Putative type I polyketide synthase gerSV Streptomyces sp. KCTC 0041BP
15
F8QPF9_9ACTO
(F8QPF9)
[query] 1 - 905 (1346)
[subject] 1 - 915 (5339)
(6 hsp)
0.0 983   57% Polyketide synthase natB Streptomyces sp. CS
16
D9WG13_9ACTO
(D9WG13)
[query] 35 - 905 (1346)
[subject] 1007 - 1883 (2116)
(2 hsp)
0.0 983   60% Modular polyketide synthase SSOG_02943 Streptomyces himastatinicus ATCC 53653
17
E0KBI0_STRVO
(E0KBI0)
[query] 3 - 912 (1346)
[subject] 5 - 932 (3955)
(4 hsp)
0.0 983   56% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
18
B4VEK8_9ACTO
(B4VEK8)
[query] 1 - 1338 (1346)
[subject] 1 - 1357 (1357)
0.0 981   45% Polyketide synthase subunit SSAG_06218 Streptomyces sp. Mg1
19
E0KBI6_STRVO
(E0KBI6)
[query] 35 - 905 (1346)
[subject] 3159 - 4044 (4996)
(6 hsp)
0.0 980   59% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
20
D1GLV8_9ACTO
(D1GLV8)
Jump to Strply_00300
[query] 35 - 905 (1346)
[subject] 1656 - 2537 (3479)
(4 hsp)
0.0 979   59% Polyketide synthase type I slgA2 Streptomyces lydicus
21
C0Z475_STRVN
(C0Z475)
[query] 1 - 918 (1346)
[subject] 1 - 918 (3447)
(3 hsp)
0.0 978   59% Type I polyketide synthase, modules 7-8 ken14 Streptomyces violaceoruber
22
B4VB12_9ACTO
(B4VB12)
[query] 4 - 914 (1346)
[subject] 3 - 916 (3203)
(4 hsp)
0.0 978   56% Polyketide synthase type I SSAG_04922 Streptomyces sp. Mg1
23
F1DI32_9ACTO
(F1DI32)
[query] 10 - 915 (1346)
[subject] 17 - 926 (3378)
(4 hsp)
0.0 975   57% TrdAII Streptomyces sp. SCSIO1666
24
A8M6C7_SALAI
(A8M6C7)
[query] 1 - 905 (1346)
[subject] 1 - 911 (5255)
(6 hsp)
0.0 973   58% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
25
D7CFC9_STRBB
(D7CFC9)
[query] 7 - 911 (1346)
[subject] 513 - 1434 (2315)
(4 hsp)
0.0 973   57% Putative type I polyketide synthase SBI_01544 Streptomyces bingchenggensis (strain BCW-1)
26
D3Y1I4_9ACTO
(D3Y1I4)
[query] 10 - 915 (1346)
[subject] 4 - 913 (3365)
(4 hsp)
0.0 972   57% TamAII Streptomyces sp. 307-9
27
E0KBI5_STRVO
(E0KBI5)
[query] 3 - 982 (1346)
[subject] 2 - 1000 (3205)
(4 hsp)
0.0 968   52% Acyl transferase StrviDRAFT_0200 Streptomyces violaceusniger Tu 4113
28
B5M9K9_STRLS
(B5M9K9)
Jump to Lasal2_00170
[query] 35 - 908 (1346)
[subject] 1790 - 2672 (5469)
(6 hsp)
0.0 967   59% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
29
D3Y1I3_9ACTO
(D3Y1I3)
[query] 35 - 911 (1346)
[subject] 1024 - 1893 (5828)
(7 hsp)
0.0 967   59% TamAI Streptomyces sp. 307-9
30
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 35 - 908 (1346)
[subject] 1750 - 2632 (5429)
(6 hsp)
0.0 966   59% Putative polyketide synthase lsd12 Streptomyces lasaliensis
31
E0KBI7_STRVO
(E0KBI7)
[query] 4 - 906 (1346)
[subject] 2 - 929 (2585)
(2 hsp)
0.0 966   57% Acyl transferase StrviDRAFT_0202 Streptomyces violaceusniger Tu 4113
32
C9YYI3_STRSW
(C9YYI3)
[query] 35 - 928 (1346)
[subject] 3198 - 4095 (5001)
(6 hsp)
0.0 966   58% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
33
A1YAM7_AMYOR
(A1YAM7)
[query] 35 - 913 (1346)
[subject] 3628 - 4498 (5723)
(5 hsp)
0.0 965   59% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
34
E0D203_9ACTO
(E0D203)
Jump to FD891_00020
[query] 4 - 905 (1346)
[subject] 27 - 956 (5571)
(6 hsp)
0.0 965   56% Polyketide synthase gfsB Streptomyces graminofaciens
35
A4FDM8_SACEN
(A4FDM8)
[query] 35 - 905 (1346)
[subject] 1068 - 1944 (4132)
(4 hsp)
0.0 964   59% Modular polyketide synthase- SACE_2875 Saccharopolyspora erythraea (strain NRRL 23338)
36
Q7WTD6_9ACTO
(Q7WTD6)
Jump to Nanch_00270
[query] 1 - 914 (1346)
[subject] 14 - 946 (3455)
(4 hsp)
0.0 964   57% NanA8 nanA8 Streptomyces nanchangensis
37
E0KBI1_STRVO
(E0KBI1)
[query] 3 - 905 (1346)
[subject] 2 - 924 (3456)
(4 hsp)
0.0 964   56% Acyl transferase StrviDRAFT_0196 Streptomyces violaceusniger Tu 4113
38
F1DI31_9ACTO
(F1DI31)
[query] 35 - 911 (1346)
[subject] 1024 - 1893 (5829)
(7 hsp)
0.0 963   59% TrdAI Streptomyces sp. SCSIO1666
39
Q49BE0_STRHY
(Q49BE0)
Jump to Herb_00180
[query] 3 - 905 (1346)
[subject] 2 - 922 (3431)
(4 hsp)
0.0 962   55% HbmAII hbmAII Streptomyces hygroscopicus
40
OL56_STRAT
(Q07017)
[query] 1 - 926 (1346)
[subject] 1653 - 2583 (3519)
(4 hsp)
0.0 961   57% Oleandomycin polyketide synthase, modules 5 and 6 orfB Streptomyces antibioticus
41
A4FH83_SACEN
(A4FH83)
[query] 35 - 909 (1346)
[subject] 3779 - 4650 (5359)
(6 hsp)
0.0 961   58% Type I modular polyketide synthase SACE_4139 Saccharopolyspora erythraea (strain NRRL 23338)
42
Q5VKR4_SACER
(Q5VKR4)
[query] 35 - 909 (1346)
[subject] 3779 - 4650 (5359)
(6 hsp)
0.0 961   58% Type I PKS pkeAIII Saccharopolyspora erythraea
Streptomyces erythraeus
43
E0D202_9ACTO
(E0D202)
Jump to FD891_00010
[query] 34 - 1066 (1346)
[subject] 2537 - 3580 (7480)
(9 hsp)
0.0 961   54% Polyketide synthase gfsA Streptomyces graminofaciens
44
Q1L0T1_STRHY
(Q1L0T1)
[query] 3 - 905 (1346)
[subject] 2 - 920 (3432)
(4 hsp)
0.0 961   55% GelB Streptomyces hygroscopicus subsp. duamyceticus
45
E0KBI4_STRVO
(E0KBI4)
[query] 35 - 923 (1346)
[subject] 4507 - 5411 (8275)
(10 hsp)
0.0 961   56% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
46
D6K441_9ACTO
(D6K441)
[query] 3 - 905 (1346)
[subject] 43 - 946 (1524)
0.0 960   56% Modular polyketide synthase SSTG_03952 Streptomyces sp. e14
47
D9WQ85_9ACTO
(D9WQ85)
[query] 37 - 905 (1346)
[subject] 1864 - 2740 (3914)
(4 hsp)
0.0 960   58% Modular polyketide synthase SSOG_05759 Streptomyces himastatinicus ATCC 53653
48
A1YAM8_AMYOR
(A1YAM8)
[query] 3 - 905 (1346)
[subject] 2 - 890 (1735)
(2 hsp)
0.0 960   57% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
49
Q84G23_STRHY
(Q84G23)
Jump to Gelda2_00090
[query] 3 - 905 (1346)
[subject] 2 - 920 (3435)
(4 hsp)
0.0 959   55% GdmAII gdmAII Streptomyces hygroscopicus
50
B4VDY6_9ACTO
(B4VDY6)
[query] 35 - 909 (1346)
[subject] 3496 - 4380 (4894)
(5 hsp)
0.0 959   58% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
51
D9WG12_9ACTO
(D9WG12)
[query] 35 - 913 (1346)
[subject] 181 - 1061 (2029)
(3 hsp)
0.0 959   59% Modular polyketide synthase SSOG_02942 Streptomyces himastatinicus ATCC 53653
52
D8HZ82_AMYMU
(D8HZ82)
[query] 8 - 905 (1346)
[subject] 3146 - 4034 (4735)
(6 hsp)
0.0 958   57% Rifamycin polyketide synthase rifA
AMED_0617
Amycolatopsis mediterranei (strain U-32)
53
O54666_AMYMD
(O54666)
Jump to Rifam_00210
[query] 8 - 905 (1346)
[subject] 3146 - 4034 (4735)
(6 hsp)
0.0 958   57% RifA
Rifamycin polyketide synthase, type 1
rifA Amycolatopsis mediterranei
Nocardia mediterranei
54
E0L076_STRVO
(E0L076)
[query] 35 - 982 (1346)
[subject] 710 - 1670 (2329)
(3 hsp)
0.0 958   55% Acyl transferase StrviDRAFT_8304 Streptomyces violaceusniger Tu 4113
55
A1YAN1_AMYOR
(A1YAN1)
[query] 10 - 905 (1346)
[subject] 6 - 881 (1921)
(2 hsp)
0.0 958   58% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
56
Q93HI8_STRAW
(Q93HI8)
Jump to Oligo_00150
[query] 35 - 905 (1346)
[subject] 1837 - 2720 (3970)
(4 hsp)
0.0 957   57% Modular polyketide synthase olmA4
SAV2892
SAV_2892
Streptomyces avermitilis
57
D7BSM1_STRBB
(D7BSM1)
[query] 1 - 914 (1346)
[subject] 1 - 933 (3439)
(4 hsp)
0.0 957   56% Type I polyketide synthase nanA8
SBI_08400
Streptomyces bingchenggensis (strain BCW-1)
58
E0KQM3_STRVO
(E0KQM3)
[query] 1 - 961 (1346)
[subject] 1 - 968 (3413)
(4 hsp)
0.0 956   55% Acyl transferase StrviDRAFT_4950 Streptomyces violaceusniger Tu 4113
59
Q9S0R3_STRAW
(Q9S0R3)
Jump to Aver_00090
[query] 35 - 1021 (1346)
[subject] 1591 - 2611 (4881)
(6 hsp)
0.0 955   54% Type I polyketide synthase AVES 4 aveA4
SAV943
SAV_943
Streptomyces avermitilis
60
B6ZIR4_STRPT
(B6ZIR4)
Jump to Pladi_00030
[query] 1 - 912 (1346)
[subject] 1 - 922 (3712)
(4 hsp)
0.0 954   55% Polyketide synthase pldAIII Streptomyces platensis
61
Q3S869_9ACTO
(Q3S869)
Jump to Conca_00080
[query] 35 - 928 (1346)
[subject] 3197 - 4098 (5006)
(6 hsp)
0.0 953   58% Modular polyketide synthase Streptomyces neyagawaensis
62
E0D206_9ACTO
(E0D206)
Jump to FD891_00050
[query] 3 - 905 (1346)
[subject] 2 - 924 (3799)
(4 hsp)
0.0 951   56% Polyketide synthase gfsE Streptomyces graminofaciens
63
B4VB03_9ACTO
(B4VB03)
[query] 4 - 918 (1346)
[subject] 20 - 941 (1650)
(2 hsp)
0.0 951   55% Polyketide synthase type I SSAG_04913 Streptomyces sp. Mg1
64
D9WG10_9ACTO
(D9WG10)
[query] 35 - 911 (1346)
[subject] 716 - 1604 (2322)
(3 hsp)
0.0 950   57% Modular polyketide synthase SSOG_02940 Streptomyces himastatinicus ATCC 53653
65
Q52V51_9ACTO
(Q52V51)
[query] 4 - 905 (1346)
[subject] 3 - 915 (3227)
(4 hsp)
0.0 950   56% Polyketide synthase type I Streptomyces aizunensis
66
F1CT53_9ACTO
(F1CT53)
[query] 23 - 912 (1346)
[subject] 2099 - 3008 (3872)
(4 hsp)
0.0 950   56% GdmAIII gdmAIII Streptomyces autolyticus
67
F1ADL8_9ACTO
(F1ADL8)
[query] 35 - 1021 (1346)
[subject] 3731 - 4797 (4884)
(6 hsp)
0.0 950   52% BafAI Streptomyces lohii
68
F8QPF8_9ACTO
(F8QPF8)
[query] 34 - 908 (1346)
[subject] 1062 - 1942 (5698)
(7 hsp)
0.0 949   59% Polyketide synthase natA Streptomyces sp. CS
69
A4FH85_SACEN
(A4FH85)
[query] 35 - 929 (1346)
[subject] 2736 - 3627 (4327)
(5 hsp)
0.0 949   58% Type I modular polyketide synthase SACE_4141 Saccharopolyspora erythraea (strain NRRL 23338)
70
Q5VKQ3_SACER
(Q5VKQ3)
[query] 35 - 929 (1346)
[subject] 2736 - 3627 (4327)
(5 hsp)
0.0 949   58% Type I PKS pkeAI Saccharopolyspora erythraea
Streptomyces erythraeus
71
Q06BM4_STRHY
(Q06BM4)
Jump to Gelda_00010
[query] 23 - 912 (1346)
[subject] 1280 - 2189 (3053)
(4 hsp)
0.0 949   56% GdmPKS gdmPKS Streptomyces hygroscopicus
72
D9W7F7_9ACTO
(D9W7F7)
[query] 3 - 915 (1346)
[subject] 2 - 931 (1355)
0.0 948   55% Modular polyketide synthase SSOG_08451 Streptomyces himastatinicus ATCC 53653
73
A8J704_9ACTO
(A8J704)
[query] 1 - 905 (1346)
[subject] 1 - 917 (5674)
(6 hsp)
0.0 948   57% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
74
D3Q134_STANL
(D3Q134)
[query] 3 - 1335 (1346)
[subject] 4 - 1296 (1305)
0.0 947   44% 6-deoxyerythronolide-B synthase Snas_4133 Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) 2.3.1.94
75
B1W490_STRGG
(B1W490)
[query] 1 - 908 (1346)
[subject] 10 - 913 (2411)
(3 hsp)
0.0 947   56% Putative type-I PKS pks1-6
SGR_6078
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
76
Q1L0T2_STRHY
(Q1L0T2)
[query] 35 - 905 (1346)
[subject] 1117 - 2003 (6855)
(7 hsp)
0.0 947   58% GelA Streptomyces hygroscopicus subsp. duamyceticus
77
D7BRE1_STRBB
(D7BRE1)
[query] 35 - 911 (1346)
[subject] 452 - 1322 (5139)
(7 hsp)
0.0 945   58% Modular polyketide synthase SBI_01983 Streptomyces bingchenggensis (strain BCW-1)
78
A8CAC5_9ACTO
(A8CAC5)
[query] 35 - 910 (1346)
[subject] 1008 - 1881 (2636)
(4 hsp)
0.0 945   59% Polyketide synthase angI Streptomyces eurythermus
79
C9YYI2_STRSW
(C9YYI2)
[query] 34 - 905 (1346)
[subject] 1810 - 2683 (3919)
(4 hsp)
0.0 944   59% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
80
A4FH82_SACEN
(A4FH82)
[query] 1 - 907 (1346)
[subject] 1 - 910 (1806)
(2 hsp)
0.0 944   56% Type I PKS modular polyketide synthas SACE_4138 Saccharopolyspora erythraea (strain NRRL 23338)
81
Q5VKR3_SACER
(Q5VKR3)
[query] 1 - 907 (1346)
[subject] 1 - 910 (1806)
(2 hsp)
0.0 944   56% Type I PKS Saccharopolyspora erythraea
Streptomyces erythraeus
82
F1CT52_9ACTO
(F1CT52)
[query] 35 - 908 (1346)
[subject] 1792 - 2687 (3418)
(4 hsp)
0.0 944   55% GdmAII gdmAII Streptomyces autolyticus
83
Q84G22_STRHY
(Q84G22)
Jump to Gelda2_00100
[query] 24 - 915 (1346)
[subject] 2108 - 3021 (3896)
(4 hsp)
0.0 943   54% GdmAIII gdmAIII Streptomyces hygroscopicus
84
A9YLB2_9ACTO
(A9YLB2)
[query] 35 - 910 (1346)
[subject] 1071 - 1944 (4436)
(5 hsp)
0.0 943   59% AngAI angAI Streptomyces eurythermus
85
E0KQM2_STRVO
(E0KQM2)
[query] 35 - 913 (1346)
[subject] 32 - 917 (1636)
(2 hsp)
0.0 943   58% Acyl transferase StrviDRAFT_4949 Streptomyces violaceusniger Tu 4113
86
C0Z474_STRVN
(C0Z474)
[query] 1 - 905 (1346)
[subject] 1 - 906 (2172)
(2 hsp)
0.0 942   57% Type I polyketide synthase, module 6 ken13 Streptomyces violaceoruber
87
Q84G24_STRHY
(Q84G24)
Jump to Gelda2_00080
[query] 35 - 905 (1346)
[subject] 1103 - 1990 (6842)
(7 hsp)
0.0 942   57% GdmAI gdmAI Streptomyces hygroscopicus
88
F8JKR1_STRCT
(F8JKR1)
[query] 35 - 931 (1346)
[subject] 1044 - 1951 (4492)
(5 hsp)
0.0 942   57% Putative Beta-ketoacyl-acyl-carrier-protein synthase II SCAT_p1475 Streptomyces cattleya NRRL 8057 2.3.1.179
89
Q6W5P9_9ACTO
(Q6W5P9)
Jump to FR008_00170
[query] 4 - 908 (1346)
[subject] 2 - 922 (5541)
(6 hsp)
0.0 942   56% FscB fscB Streptomyces sp. FR-008
90
D9W5R3_9ACTO
(D9W5R3)
[query] 7 - 907 (1346)
[subject] 20 - 931 (1616)
(2 hsp)
0.0 942   56% Polyketide synthase type I SSNG_07493 Streptomyces sp. C
91
A1YAM6_AMYOR
(A1YAM6)
[query] 35 - 913 (1346)
[subject] 1771 - 2645 (3834)
(5 hsp)
0.0 941   57% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
92
E0KFI6_STRVO
(E0KFI6)
[query] 1 - 921 (1346)
[subject] 1 - 926 (1658)
(2 hsp)
0.0 941   55% 6-deoxyerythronolide-B synthase StrviDRAFT_1369 Streptomyces violaceusniger Tu 4113 2.3.1.94
93
Q1L0T0_STRHY
(Q1L0T0)
[query] 24 - 915 (1346)
[subject] 2108 - 3021 (3888)
(4 hsp)
0.0 940   54% GelC Streptomyces hygroscopicus subsp. duamyceticus
94
B5M9L1_STRLS
(B5M9L1)
Jump to Lasal2_00190
[query] 1 - 905 (1346)
[subject] 4 - 912 (1647)
(2 hsp)
0.0 940   55% Lasalocid modular polyketide synthase lasAIV Streptomyces lasaliensis
95
D7CC08_STRBB
(D7CC08)
[query] 3 - 905 (1346)
[subject] 2 - 934 (5530)
(6 hsp)
0.0 940   55% Putative type I polyketide synthase pks5-2
SBI_01382
Streptomyces bingchenggensis (strain BCW-1)
96
B6ZK67_STRLS
(B6ZK67)
Jump to Lasal_00160
[query] 1 - 905 (1346)
[subject] 4 - 912 (1647)
(2 hsp)
0.0 940   55% Putative polyketide synthase lsd14 Streptomyces lasaliensis
97
B2HR35_MYCMM
(B2HR35)
[query] 1 - 905 (1346)
[subject] 1 - 911 (2120)
(2 hsp)
0.0 940   55% Polyketide synthase Pks7 pks7
MMAR_2471
Mycobacterium marinum (strain ATCC BAA-535 / M)
98
D8HZ86_AMYMU
(D8HZ86)
[query] 35 - 908 (1346)
[subject] 1702 - 2569 (3413)
(4 hsp)
0.0 940   57% Rifamycin polyketide synthase rifE
AMED_0621
Amycolatopsis mediterranei (strain U-32)
99
O54593_AMYMD
(O54593)
Jump to Rifam_00250
[query] 35 - 908 (1346)
[subject] 1702 - 2569 (3413)
(4 hsp)
0.0 940   57% RifE
Rifamycin polyketide synthase, type 1
rifE Amycolatopsis mediterranei
Nocardia mediterranei
100
E0KQM1_STRVO
(E0KQM1)
[query] 1 - 918 (1346)
[subject] 1 - 943 (1698)
(2 hsp)
0.0 939   55% Acyl transferase StrviDRAFT_4948 Streptomyces violaceusniger Tu 4113
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9ZGI2_9ACTO
(Q9ZGI2)
[query] 1 - 1346 (1346)
[subject] 1 - 1346 (1346)
0.0 2678   100%
Product
Type I polyketide synthase PikAIV
Gene
pikAIV
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
2uniprot[Pubmed] 12379102 [Medline] 22266839
Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.(Biochemistry) [2002]
3uniprot[Pubmed] 16969373
Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.(Nat. Chem. Biol.) [2006]
4uniprot[Pubmed] 16969372
Structural basis for macrolactonization by the pikromycin thioesterase.(Nat. Chem. Biol.) [2006]
5uniprot[Pubmed] 19146481
Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.(ACS Chem. Biol.) [2009]
[pubmed all]
2
Q9ZGI4_9ACTO
(Q9ZGI4)
Jump to Pikro_00040
[query] 2 - 911 (1346)
[subject] 3 - 920 (3739)
(4 hsp)
0.0 1345   75%
Product
Type I polyketide synthase PikAII
Gene
pikAII
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
3
Q9ZGI3_9ACTO
(Q9ZGI3)
Jump to Pikro_00050
[query] 1 - 913 (1346)
[subject] 1 - 912 (1562)
(2 hsp)
0.0 1336   74%
Product
Type I polyketide synthase PikAIII
Gene
pikAIII
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
2uniprot[Pubmed] 19146481
Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.(ACS Chem. Biol.) [2009]
[pubmed all]
4
Q9ZGI5_9ACTO
(Q9ZGI5)
Jump to Pikro_00030
[query] 35 - 920 (1346)
[subject] 1109 - 1999 (4613)
(5 hsp)
0.0 1244   72%
Product
Type I polyketide synthase PikAI
Gene
pikAI
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
5
B6ZK66_STRLS
(B6ZK66)
Jump to Lasal_00150
[query] 1 - 1030 (1346)
[subject] 6 - 1042 (1113)
0.0 1008   54%
Product
Putative polyketide synthase
Gene
lsd13
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
8
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 909 (1346)
[subject] 1 - 908 (5060)
(6 hsp)
0.0 1001   59%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
9
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 909 (1346)
[subject] 1 - 908 (5060)
(6 hsp)
0.0 1001   59%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
13
D1GLV9_9ACTO
(D1GLV9)
Jump to Strply_00310
[query] 35 - 918 (1346)
[subject] 4200 - 5099 (6171)
(7 hsp)
0.0 987   59%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
14
Q331Q2_9ACTO
(Q331Q2)
[query] 1 - 1338 (1346)
[subject] 1 - 1357 (1357)
0.0 984   45%
Product
Putative type I polyketide synthase
Gene
gerSV
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
15
F8QPF9_9ACTO
(F8QPF9)
[query] 1 - 905 (1346)
[subject] 1 - 915 (5339)
(6 hsp)
0.0 983   57%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
20
D1GLV8_9ACTO
(D1GLV8)
Jump to Strply_00300
[query] 35 - 905 (1346)
[subject] 1656 - 2537 (3479)
(4 hsp)
0.0 979   59%
Product
Polyketide synthase type I
Gene
slgA2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
23
F1DI32_9ACTO
(F1DI32)
[query] 10 - 915 (1346)
[subject] 17 - 926 (3378)
(4 hsp)
0.0 975   57%
Product
TrdAII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
25
D7CFC9_STRBB
(D7CFC9)
[query] 7 - 911 (1346)
[subject] 513 - 1434 (2315)
(4 hsp)
0.0 973   57%
Product
Putative type I polyketide synthase
Gene
SBI_01544
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
26
D3Y1I4_9ACTO
(D3Y1I4)
[query] 10 - 915 (1346)
[subject] 4 - 913 (3365)
(4 hsp)
0.0 972   57%
Product
TamAII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
29
D3Y1I3_9ACTO
(D3Y1I3)
[query] 35 - 911 (1346)
[subject] 1024 - 1893 (5828)
(7 hsp)
0.0 967   59%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
30
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 35 - 908 (1346)
[subject] 1750 - 2632 (5429)
(6 hsp)
0.0 966   59%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
32
C9YYI3_STRSW
(C9YYI3)
[query] 35 - 928 (1346)
[subject] 3198 - 4095 (5001)
(6 hsp)
0.0 966   58%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
33
A1YAM7_AMYOR
(A1YAM7)
[query] 35 - 913 (1346)
[subject] 3628 - 4498 (5723)
(5 hsp)
0.0 965   59%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
34
E0D203_9ACTO
(E0D203)
Jump to FD891_00020
[query] 4 - 905 (1346)
[subject] 27 - 956 (5571)
(6 hsp)
0.0 965   56%
Product
Polyketide synthase
Gene
gfsB
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
35
A4FDM8_SACEN
(A4FDM8)
[query] 35 - 905 (1346)
[subject] 1068 - 1944 (4132)
(4 hsp)
0.0 964   59%
Product
Modular polyketide synthase-
Gene
SACE_2875
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
36
Q7WTD6_9ACTO
(Q7WTD6)
Jump to Nanch_00270
[query] 1 - 914 (1346)
[subject] 14 - 946 (3455)
(4 hsp)
0.0 964   57%
Product
NanA8
Gene
nanA8
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
38
F1DI31_9ACTO
(F1DI31)
[query] 35 - 911 (1346)
[subject] 1024 - 1893 (5829)
(7 hsp)
0.0 963   59%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
39
Q49BE0_STRHY
(Q49BE0)
Jump to Herb_00180
[query] 3 - 905 (1346)
[subject] 2 - 922 (3431)
(4 hsp)
0.0 962   55%
Product
HbmAII
Gene
hbmAII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
40
OL56_STRAT
(Q07017)
[query] 1 - 926 (1346)
[subject] 1653 - 2583 (3519)
(4 hsp)
0.0 961   57%
Product
Oleandomycin polyketide synthase, modules 5 and 6
Gene
orfB
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 8107683 [Medline] 94150470
Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence.(Mol. Gen. Genet.) [1994]
41
A4FH83_SACEN
(A4FH83)
[query] 35 - 909 (1346)
[subject] 3779 - 4650 (5359)
(6 hsp)
0.0 961   58%
Product
Type I modular polyketide synthase
Gene
SACE_4139
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
42
Q5VKR4_SACER
(Q5VKR4)
[query] 35 - 909 (1346)
[subject] 3779 - 4650 (5359)
(6 hsp)
0.0 961   58%
Product
Type I PKS
Gene
pkeAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
43
E0D202_9ACTO
(E0D202)
Jump to FD891_00010
[query] 34 - 1066 (1346)
[subject] 2537 - 3580 (7480)
(9 hsp)
0.0 961   54%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
44
Q1L0T1_STRHY
(Q1L0T1)
[query] 3 - 905 (1346)
[subject] 2 - 920 (3432)
(4 hsp)
0.0 961   55%
Product
GelB
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
48
A1YAM8_AMYOR
(A1YAM8)
[query] 3 - 905 (1346)
[subject] 2 - 890 (1735)
(2 hsp)
0.0 960   57%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
49
Q84G23_STRHY
(Q84G23)
Jump to Gelda2_00090
[query] 3 - 905 (1346)
[subject] 2 - 920 (3435)
(4 hsp)
0.0 959   55%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
52
D8HZ82_AMYMU
(D8HZ82)
[query] 8 - 905 (1346)
[subject] 3146 - 4034 (4735)
(6 hsp)
0.0 958   57%
Product
Rifamycin polyketide synthase
Gene
rifA
AMED_0617
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
53
O54666_AMYMD
(O54666)
Jump to Rifam_00210
[query] 8 - 905 (1346)
[subject] 3146 - 4034 (4735)
(6 hsp)
0.0 958   57%
Product
RifA
Rifamycin polyketide synthase, type 1
Gene
rifA
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
55
A1YAN1_AMYOR
(A1YAN1)
[query] 10 - 905 (1346)
[subject] 6 - 881 (1921)
(2 hsp)
0.0 958   58%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
56
Q93HI8_STRAW
(Q93HI8)
Jump to Oligo_00150
[query] 35 - 905 (1346)
[subject] 1837 - 2720 (3970)
(4 hsp)
0.0 957   57%
Product
Modular polyketide synthase
Gene
olmA4
SAV2892
SAV_2892
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
57
D7BSM1_STRBB
(D7BSM1)
[query] 1 - 914 (1346)
[subject] 1 - 933 (3439)
(4 hsp)
0.0 957   56%
Product
Type I polyketide synthase
Gene
nanA8
SBI_08400
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
59
Q9S0R3_STRAW
(Q9S0R3)
Jump to Aver_00090
[query] 35 - 1021 (1346)
[subject] 1591 - 2611 (4881)
(6 hsp)
0.0 955   54%
Product
Type I polyketide synthase AVES 4
Gene
aveA4
SAV943
SAV_943
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
60
B6ZIR4_STRPT
(B6ZIR4)
Jump to Pladi_00030
[query] 1 - 912 (1346)
[subject] 1 - 922 (3712)
(4 hsp)
0.0 954   55%
Product
Polyketide synthase
Gene
pldAIII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
61
Q3S869_9ACTO
(Q3S869)
Jump to Conca_00080
[query] 35 - 928 (1346)
[subject] 3197 - 4098 (5006)
(6 hsp)
0.0 953   58%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
62
E0D206_9ACTO
(E0D206)
Jump to FD891_00050
[query] 3 - 905 (1346)
[subject] 2 - 924 (3799)
(4 hsp)
0.0 951   56%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
65
Q52V51_9ACTO
(Q52V51)
[query] 4 - 905 (1346)
[subject] 3 - 915 (3227)
(4 hsp)
0.0 950   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
66
F1CT53_9ACTO
(F1CT53)
[query] 23 - 912 (1346)
[subject] 2099 - 3008 (3872)
(4 hsp)
0.0 950   56%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
68
F8QPF8_9ACTO
(F8QPF8)
[query] 34 - 908 (1346)
[subject] 1062 - 1942 (5698)
(7 hsp)
0.0 949   59%
Product
Polyketide synthase
Gene
natA
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
69
A4FH85_SACEN
(A4FH85)
[query] 35 - 929 (1346)
[subject] 2736 - 3627 (4327)
(5 hsp)
0.0 949   58%
Product
Type I modular polyketide synthase
Gene
SACE_4141
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
70
Q5VKQ3_SACER
(Q5VKQ3)
[query] 35 - 929 (1346)
[subject] 2736 - 3627 (4327)
(5 hsp)
0.0 949   58%
Product
Type I PKS
Gene
pkeAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
71
Q06BM4_STRHY
(Q06BM4)
Jump to Gelda_00010
[query] 23 - 912 (1346)
[subject] 1280 - 2189 (3053)
(4 hsp)
0.0 949   56%
Product
GdmPKS
Gene
gdmPKS
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 18214443
The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.(Arch. Microbiol.) [2008]
74
D3Q134_STANL
(D3Q134)
[query] 3 - 1335 (1346)
[subject] 4 - 1296 (1305)
0.0 947   44%
Product
6-deoxyerythronolide-B synthase
Gene
Snas_4133
Organism
Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]
75
B1W490_STRGG
(B1W490)
[query] 1 - 908 (1346)
[subject] 10 - 913 (2411)
(3 hsp)
0.0 947   56%
Product
Putative type-I PKS
Gene
pks1-6
SGR_6078
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
76
Q1L0T2_STRHY
(Q1L0T2)
[query] 35 - 905 (1346)
[subject] 1117 - 2003 (6855)
(7 hsp)
0.0 947   58%
Product
GelA
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
77
D7BRE1_STRBB
(D7BRE1)
[query] 35 - 911 (1346)
[subject] 452 - 1322 (5139)
(7 hsp)
0.0 945   58%
Product
Modular polyketide synthase
Gene
SBI_01983
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
79
C9YYI2_STRSW
(C9YYI2)
[query] 34 - 905 (1346)
[subject] 1810 - 2683 (3919)
(4 hsp)
0.0 944   59%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
80
A4FH82_SACEN
(A4FH82)
[query] 1 - 907 (1346)
[subject] 1 - 910 (1806)
(2 hsp)
0.0 944   56%
Product
Type I PKS modular polyketide synthas
Gene
SACE_4138
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
81
Q5VKR3_SACER
(Q5VKR3)
[query] 1 - 907 (1346)
[subject] 1 - 910 (1806)
(2 hsp)
0.0 944   56%
Product
Type I PKS
Gene
 
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
82
F1CT52_9ACTO
(F1CT52)
[query] 35 - 908 (1346)
[subject] 1792 - 2687 (3418)
(4 hsp)
0.0 944   55%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
83
Q84G22_STRHY
(Q84G22)
Jump to Gelda2_00100
[query] 24 - 915 (1346)
[subject] 2108 - 3021 (3896)
(4 hsp)
0.0 943   54%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
87
Q84G24_STRHY
(Q84G24)
Jump to Gelda2_00080
[query] 35 - 905 (1346)
[subject] 1103 - 1990 (6842)
(7 hsp)
0.0 942   57%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
89
Q6W5P9_9ACTO
(Q6W5P9)
Jump to FR008_00170
[query] 4 - 908 (1346)
[subject] 2 - 922 (5541)
(6 hsp)
0.0 942   56%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
91
A1YAM6_AMYOR
(A1YAM6)
[query] 35 - 913 (1346)
[subject] 1771 - 2645 (3834)
(5 hsp)
0.0 941   57%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
93
Q1L0T0_STRHY
(Q1L0T0)
[query] 24 - 915 (1346)
[subject] 2108 - 3021 (3888)
(4 hsp)
0.0 940   54%
Product
GelC
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
95
D7CC08_STRBB
(D7CC08)
[query] 3 - 905 (1346)
[subject] 2 - 934 (5530)
(6 hsp)
0.0 940   55%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
96
B6ZK67_STRLS
(B6ZK67)
Jump to Lasal_00160
[query] 1 - 905 (1346)
[subject] 4 - 912 (1647)
(2 hsp)
0.0 940   55%
Product
Putative polyketide synthase
Gene
lsd14
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
97
B2HR35_MYCMM
(B2HR35)
[query] 1 - 905 (1346)
[subject] 1 - 911 (2120)
(2 hsp)
0.0 940   55%
Product
Polyketide synthase Pks7
Gene
pks7
MMAR_2471
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
98
D8HZ86_AMYMU
(D8HZ86)
[query] 35 - 908 (1346)
[subject] 1702 - 2569 (3413)
(4 hsp)
0.0 940   57%
Product
Rifamycin polyketide synthase
Gene
rifE
AMED_0621
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
99
O54593_AMYMD
(O54593)
Jump to Rifam_00250
[query] 35 - 908 (1346)
[subject] 1702 - 2569 (3413)
(4 hsp)
0.0 940   57%
Product
RifE
Rifamycin polyketide synthase, type 1
Gene
rifE
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]