BLAST table : Resis_00060

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q70DX2_9ACTO
(Q70DX2)		 
[query] 1 - 428 (428)
[subject] 1 - 428 (428)
 0.0 867   100% RemA protein remA Streptomyces resistomycificus
2
 D6U575_9CHLR
(D6U575)		 
[query] 1 - 420 (428)
[subject] 1 - 420 (426)
 1e-163 578   64% Beta-ketoacyl synthase Krac_2391 Ktedonobacter racemifer DSM 44963
3
 D6U202_9CHLR
(D6U202)		 
[query] 1 - 418 (428)
[subject] 1 - 416 (425)
 1e-111 408   54% Beta-ketoacyl synthase Krac_1519 Ktedonobacter racemifer DSM 44963
4
 D5ZY76_9ACTO
(D5ZY76)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 4e-98 363   46% 3-oxoacyl-(Acyl-carrier-protein) synthase SSFG_06314 Streptomyces ghanaensis ATCC 14672
5
 F4FBT7_VERMA
(F4FBT7)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (420)
 9e-97 358   47% 3-oxoacyl-(Acyl-carrier-protein) synthase 2 VAB18032_18175 Verrucosispora maris (strain AB-18-032)
6
 F2RIV6_STRVP
(F2RIV6)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 1e-95 355   45% Polyketide beta-ketoacyl synthase WhiE-KS SVEN_6796 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
7
 D6K4R1_9ACTO
(D6K4R1)		 
[query] 2 - 427 (428)
[subject] 3 - 422 (422)
 5e-95 352   45% Polyketide beta-ketoacyl synthase 1 SSTG_02042 Streptomyces sp. e14
8
 D2AY44_STRRD
(D2AY44)		 
[query] 2 - 424 (428)
[subject] 5 - 419 (422)
 2e-94 350   46% 3-oxoacyl-(Acyl-carrier-protein) synthase II Sros_4150 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
9
 KAS1_STRCN
(Q02578)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 4e-94 350   46% Putative polyketide beta-ketoacyl synthase 1 curA Streptomyces cyaneus
Streptomyces curacoi		 2.3.1.-
10
 E0KUS3_STRVO
(E0KUS3)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 4e-94 350   46% Beta-ketoacyl synthase StrviDRAFT_6401 Streptomyces violaceusniger Tu 4113
11
 D9XHA7_STRVR
(D9XHA7)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-94 349   45% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSQG_05444 Streptomyces viridochromogenes DSM 40736
12
 D9XXA1_9ACTO
(D9XXA1)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-94 349   47% Polyketide beta-ketoacyl synthase 1 SSRG_00591 Streptomyces griseoflavus Tu4000
13
 F3NHY3_9ACTO
(F3NHY3)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 6e-94 349   45% Polyketide beta-ketoacyl synthase alpha SGM_2747 Streptomyces griseoaurantiacus M045
14
 D1XLU9_9ACTO
(D1XLU9)		 
[query] 14 - 428 (428)
[subject] 15 - 421 (422)
 1e-93 348   47% Beta-ketoacyl synthase SACTEDRAFT_3659 Streptomyces sp. SA3_actE
15
 B1GSN1_9ACTO
(B1GSN1)		 Jump to Bena_00090 
[query] 2 - 418 (428)
[subject] 5 - 415 (423)
 1e-93 348   44% BenA protein benA Streptomyces sp. A2991200 2.3.1.-
16
 D2S3S4_GEOOG
(D2S3S4)		 
[query] 2 - 418 (428)
[subject] 6 - 422 (431)
 1e-93 348   43% Beta-ketoacyl synthase Gobs_0146 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
17
 Q9F6E8_STRCU
(Q9F6E8)		 
[query] 2 - 427 (428)
[subject] 3 - 422 (422)
 3e-93 347   44% PKSA beta-ketoacylsynthase subunit alpha Streptomyces collinus
18
 KAS1_STRHA
(Q05356)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 3e-93 347   46% Putative polyketide beta-ketoacyl synthase 1
Polyketide condensing enzyme		 sch1 Streptomyces halstedii 2.3.1.-
19
 D6X9Z4_STRPR
(D6X9Z4)		 
[query] 2 - 426 (428)
[subject] 3 - 419 (421)
 7e-93 345   45% 3-oxoacyl-ACP synthase I SSDG_06094 Streptomyces pristinaespiralis ATCC 25486
20
 E8S3J8_MICSL
(E8S3J8)		 
[query] 2 - 420 (428)
[subject] 4 - 416 (423)
 1e-92 344   45% Beta-ketoacyl synthase ML5_4899 Micromonospora sp. (strain L5)
21
 D1XRE9_9ACTO
(D1XRE9)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-92 344   44% Beta-ketoacyl synthase SACTEDRAFT_5259 Streptomyces sp. SA3_actE
22
 D9SXX9_MICAI
(D9SXX9)		 
[query] 2 - 420 (428)
[subject] 4 - 416 (422)
 3e-92 343   45% Beta-ketoacyl synthase Micau_3496 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
23
 Q54173_STRFR
(Q54173)		 Jump to Urd_00120 
[query] 2 - 418 (428)
[subject] 7 - 417 (426)
 4e-92 343   44% Putative ketoacyl synthase UrdA Streptomyces fradiae
Streptomyces roseoflavus
24
 Q9FD19_STRCU
(Q9FD19)		 
[query] 2 - 418 (428)
[subject] 6 - 416 (428)
 9e-92 342   46% Ketosynthase alpha subunit rubA Streptomyces collinus
25
 D9UKN5_9ACTO
(D9UKN5)		 
[query] 2 - 426 (428)
[subject] 3 - 419 (425)
 2e-91 341   43% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSLG_05751 Streptomyces sp. SPB78
26
 D6AV07_STRFL
(D6AV07)		 
[query] 2 - 418 (428)
[subject] 7 - 417 (427)
 2e-91 340   44% Beta-ketoacyl synthase SSGG_03669 Streptomyces roseosporus NRRL 15998
27
 D9WVC5_9ACTO
(D9WVC5)		 
[query] 2 - 418 (428)
[subject] 3 - 412 (419)
 4e-91 340   47% Putative polyketide beta-ketoacyl synthase 1 SSOG_02014 Streptomyces himastatinicus ATCC 53653
28
 D1H0A1_9ACTO
(D1H0A1)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 8e-91 338   44% Putative ketoacyl synthase (KSa) chryA Streptomyces albaduncus
29
 B4VBE8_9ACTO
(B4VBE8)		 
[query] 14 - 418 (428)
[subject] 16 - 414 (423)
 1e-90 338   47% WhiESaIII SSAG_05076 Streptomyces sp. Mg1
30
 C9Z5P4_STRSW
(C9Z5P4)		 
[query] 4 - 427 (428)
[subject] 1 - 418 (418)
 3e-90 337   43% Putative polyketide beta-ketoacyl synthase 1 sppA
SCAB_43301		 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
31
 E8W0T3_STRFA
(E8W0T3)		 
[query] 14 - 428 (428)
[subject] 16 - 422 (423)
 4e-90 336   45% Beta-ketoacyl synthase Sfla_6019 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
32
 Q70J88_STRGR
(Q70J88)		 Jump to Chro_00100 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-90 336   45% Ketosynthase cmmP Streptomyces griseus subsp. griseus
33
 O68918_9ACTO
(O68918)		 Jump to Fren_00120 
[query] 2 - 426 (428)
[subject] 3 - 419 (425)
 6e-90 336   43% Ketoacyl synthase frnL Streptomyces roseofulvus
34
 Q54994_9ACTO
(Q54994)		 
[query] 2 - 426 (428)
[subject] 3 - 419 (425)
 1e-89 335   43% Putative uncharacterized protein Streptomyces roseofulvus
35
 D9UBT2_STRPR
(D9UBT2)		 
[query] 1 - 418 (428)
[subject] 1 - 412 (422)
 1e-89 335   43% Putative ketoacylsynthase, chain length factor alpha-subunit cpp3 Streptomyces pristinaespiralis 2.3.1.179
36
 B5HIW3_STRPR
(B5HIW3)		 
[query] 1 - 418 (428)
[subject] 1 - 412 (422)
 1e-89 335   43% Ketoacyl synthase SSDG_05100 Streptomyces pristinaespiralis ATCC 25486
37
 B5HT08_9ACTO
(B5HT08)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-89 334   45% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSEG_09024 Streptomyces sviceus ATCC 29083
38
 Q9LCH6_9ACTO
(Q9LCH6)		 
[query] 9 - 397 (428)
[subject] 1 - 383 (393)
 2e-89 334   46% Ketosynthase ks Streptomyces venezuelae
39
 Q54217_STRGR
(Q54217)		 Jump to Griseu_00010 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 2e-89 334   45% Ketosynthase Streptomyces griseus
40
 E2PVZ8_STRCL
(E2PVZ8)		 
[query] 21 - 428 (428)
[subject] 22 - 421 (422)
 3e-89 333   45% Putative polyketide beta-ketoacyl synthase 1 sppA
SCLAV_4915		 Streptomyces clavuligerus ATCC 27064 2.3.1.-
41
 Q2PA07_9ACTO
(Q2PA07)		 Jump to Stref_00080 
[query] 2 - 420 (428)
[subject] 3 - 415 (422)
 5e-89 333   43% Ketoacyl synthase stfP Streptomyces steffisburgensis
42
 C0JWB4_9ACTO
(C0JWB4)		 Jump to Polk_00190 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-89 332   44% PokP1 pokP1 Streptomyces diastatochromogenes
43
 D7C2K2_STRBB
(D7C2K2)		 
[query] 2 - 418 (428)
[subject] 3 - 416 (424)
 5e-89 332   45% 3-oxoacyl-ACP synthase I sppA
SBI_02764		 Streptomyces bingchenggensis (strain BCW-1)
44
 O32451_9ACTO
(O32451)		 
[query] 2 - 420 (428)
[subject] 10 - 422 (425)
 9e-89 332   44% ORF 1
PdmA		 pdmA Actinomadura hibisca
45
 C7N0D1_SACVD
(C7N0D1)		 
[query] 1 - 418 (428)
[subject] 1 - 413 (426)
 1e-88 332   42% 3-oxoacyl-(Acyl-carrier-protein) synthase Svir_33690 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
46
 D9VMP6_9ACTO
(D9VMP6)		 
[query] 14 - 418 (428)
[subject] 16 - 414 (423)
 2e-88 331   46% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSNG_00654 Streptomyces sp. C
47
 D9W5B0_9ACTO
(D9W5B0)		 
[query] 2 - 425 (428)
[subject] 3 - 420 (423)
 2e-88 330   43% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSNG_07340 Streptomyces sp. C
48
 B6SEF1_9ACTO
(B6SEF1)		 Jump to Alnu_00060 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 3e-88 330   43% AlnL ketoacyl synthase alpha alnL Streptomyces sp. CM020
49
 D6EUH1_STRLI
(D6EUH1)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 4e-88 330   44% Polyketide beta-ketoacyl synthase alpha SSPG_02365 Streptomyces lividans TK24
50
 KAS1_STRCO
(P23155)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 4e-88 330   44% Putative polyketide beta-ketoacyl synthase 1
WhiE ORF III		 SCO5318
SC6G9.15		 Streptomyces coelicolor 2.3.1.-
51
 Q0MRN5_9ACTO
(Q0MRN5)		 
[query] 1 - 418 (428)
[subject] 1 - 409 (421)
 4e-88 330   44% Putative beta-ketoacyl synthase Streptomyces toxytricini
52
 Q2J5J3_FRASC
(Q2J5J3)		 
[query] 2 - 428 (428)
[subject] 5 - 423 (424)
 6e-88 329   41% 3-oxoacyl-[acyl-carrier-protein] synthase II Francci3_4101 Frankia sp. (strain CcI3) 2.3.1.41
53
 Q2HR20_9ACTO
(Q2HR20)		 Jump to Sch475_00380 
[query] 5 - 418 (428)
[subject] 1 - 408 (420)
 7e-88 329   43% Putative ketoacyl synthase schP8 Streptomyces sp. SCC 2136
54
 C7Q5R5_CATAD
(C7Q5R5)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 7e-88 329   44% Beta-ketoacyl synthase Caci_1086 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
55
 E3IZH4_FRASU
(E3IZH4)		 
[query] 2 - 418 (428)
[subject] 4 - 426 (434)
 8e-88 328   44% Beta-ketoacyl synthase FraEuI1c_4753 Frankia sp. (strain EuI1c)
56
 Q54495_STRNO
(Q54495)		 Jump to Nogl_00370 
[query] 2 - 418 (428)
[subject] 7 - 418 (430)
 1e-87 328   44% Snoa1 snoa1 Streptomyces nogalater
57
 F8B4X8_9ACTO
(F8B4X8)		 
[query] 19 - 427 (428)
[subject] 22 - 424 (459)
 1e-87 328   45% Beta-ketoacyl-acyl-carrier-protein synthase II FsymDg_2768 Frankia symbiont of Datisca glomerata 2.3.1.179
58
 Q6VMI7_STRAM
(Q6VMI7)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-87 328   44% Putative ketoacyl synthase alpA Streptomyces ambofaciens
59
 Q1RQS0_STRAM
(Q1RQS0)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-87 328   44% Putative ketoacyl synthase alpA
SAMT0165
SAMT0166		 Streptomyces ambofaciens ATCC 23877
60
 Q8KSW4_9ACTO
(Q8KSW4)		 Jump to Griseo_00280 
[query] 2 - 418 (428)
[subject] 3 - 414 (426)
 2e-87 328   43% Putative ketosynthase alpha GrhA grhA Streptomyces sp. JP95
61
 D1H0K0_9ACTO
(D1H0K0)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-87 327   45% Putative ketoacyl synthase ravA Streptomyces sp. C23201NS3
62
 Q93LZ8_STRAU
(Q93LZ8)		 
[query] 2 - 425 (428)
[subject] 3 - 420 (423)
 2e-87 327   42% B-ketoacyl-ACP synthase-like protein aur2A Streptomyces aureofaciens
63
 Q7MZT3_PHOLL
(Q7MZT3)		 
[query] 2 - 424 (428)
[subject] 12 - 427 (428)
 3e-87 327   42% Similar to polyketide beta-ketoacyl synthase plu4191 Photorhabdus luminescens subsp. laumondii (strain TT01)
64
 F8B665_9ACTO
(F8B665)		 
[query] 1 - 418 (428)
[subject] 1 - 422 (430)
 3e-87 327   43% Beta-ketoacyl-acyl-carrier-protein synthase II FsymDg_0492 Frankia symbiont of Datisca glomerata 2.3.1.179
65
 D5MRH6_9ACTO
(D5MRH6)		 
[query] 2 - 424 (428)
[subject] 4 - 421 (423)
 3e-87 327   43% Putative ketosynthase hrbC Streptomyces sp. 2238-SVT4
66
 Q56HA2_STRAU
(Q56HA2)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 3e-87 327   44% Aur1D aur1D Streptomyces aureofaciens
67
 D9W582_9ACTO
(D9W582)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-87 326   41% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSNG_07312 Streptomyces sp. C
68
 Q93LY4_9ACTO
(Q93LY4)		 
[query] 2 - 424 (428)
[subject] 3 - 420 (422)
 5e-87 326   42% Ketosynthase PgaA pgaA Streptomyces sp. PGA64
69
 Q84CI2_9ACTO
(Q84CI2)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 7e-87 325   42% Putative ketoacyl synthase pd2A Streptomyces sp. WP 4669
70
 E4NJ51_KITSK
(E4NJ51)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 9e-87 325   46% Putative 3-oxoacyl-[acyl-carrier-protein] synthase KSE_72440 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae		 2.3.1.-
71
 Q83X35_STRRO
(Q83X35)		 
[query] 1 - 418 (428)
[subject] 1 - 411 (421)
 9e-87 325   43% Beta-ketoacyl synthase alpha-subunit rocA Streptomyces rochei
Streptomyces parvullus
72
 E2EKJ9_9ACTO
(E2EKJ9)		 
[query] 5 - 423 (428)
[subject] 6 - 418 (421)
 2e-86 324   42% Ketosynthase sanF Streptomyces sp. SANK 61196
73
 Q9XE00_9ACTO
(Q9XE00)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-86 324   43% Polyketide synthase Actinomadura verrucosospora
74
 Q8VWB3_9ACTO
(Q8VWB3)		 
[query] 2 - 428 (428)
[subject] 4 - 423 (423)
 2e-86 324   44% AknB aknB Streptomyces galilaeus
75
 D5UC54_CELFN
(D5UC54)		 
[query] 1 - 418 (428)
[subject] 4 - 415 (422)
 2e-86 324   44% Beta-ketoacyl synthase Cfla_3334 Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
76
 Q9RHT8_STRRO
(Q9RHT8)		 
[query] 1 - 418 (428)
[subject] 1 - 409 (419)
 2e-86 324   44% Ketosynthase orf1 Streptomyces rochei
Streptomyces parvullus
77
 Q5U8L3_9ACTO
(Q5U8L3)		 
[query] 4 - 418 (428)
[subject] 1 - 409 (419)
 2e-86 324   42% Type II PKS ketoacyl synthase aspA Streptomyces spiramyceticus
78
 F4F9S3_VERMA
(F4F9S3)		 
[query] 2 - 422 (428)
[subject] 4 - 418 (424)
 3e-86 323   44% Beta-ketoacyl synthase VAB18032_23755 Verrucosispora maris (strain AB-18-032)
79
 Q9F6E0_9ACTO
(Q9F6E0)		 Jump to R1128_00020 
[query] 5 - 427 (428)
[subject] 1 - 417 (417)
 6e-86 322   40% Beta-ketoacylsynthase I zhuB Streptomyces sp. R1128
80
 B5G886_9ACTO
(B5G886)		 
[query] 2 - 418 (428)
[subject] 5 - 415 (424)
 7e-86 322   44% Tetracenomycin C polyketide beta-ketoacyl synthase 1 SSBG_00494 Streptomyces sp. SPB74
81
 Q84CJ7_9ACTO
(Q84CJ7)		 
[query] 2 - 418 (428)
[subject] 5 - 415 (424)
 7e-86 322   43% Putative ketoacyl synthase kinA Streptomyces murayamaensis
82
 Q0JWA1_STRAM
(Q0JWA1)		 
[query] 5 - 418 (428)
[subject] 1 - 408 (417)
 7e-86 322   44% Putative ketoacyl synthase DSMT0185 Streptomyces ambofaciens
83
 Q53671_STRAA
(Q53671)		 Jump to Mith_00140 
[query] 2 - 418 (428)
[subject] 3 - 412 (422)
 8e-86 322   43% Ketoacyl synthase mtmP Streptomyces argillaceus
84
 Q9LCH5_STRNO
(Q9LCH5)		 
[query] 9 - 396 (428)
[subject] 1 - 382 (393)
 9e-86 322   44% Ketosynthase ks Streptomyces nogalater
85
 C4NYJ9_9ACTO
(C4NYJ9)		 
[query] 3 - 418 (428)
[subject] 4 - 413 (422)
 2e-85 321   44% SaqA saqA Micromonospora sp. Tu 6368
86
 Q9X461_STRAE
(Q9X461)		 Jump to Naphcy_00010 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 2e-85 321   42% Beta-ketoacyl synthase/acyl transferase ncnA Streptomyces arenae
87
 F6K0W5_9BACT
(F6K0W5)		 
[query] 2 - 420 (428)
[subject] 4 - 416 (423)
 2e-85 320   43% Ketoacyl synthase uncultured bacterium BAC AB649/1850
88
 Q9L551_9ACTO
(Q9L551)		 Jump to Acla_00070 
[query] 2 - 428 (428)
[subject] 4 - 423 (423)
 8e-85 318   43% AknB aknB Streptomyces galilaeus
89
 Q93HM2_STRAW
(Q93HM2)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 1e-84 318   43% 3-oxoacyl-(Acyl carrier protein) synthase I
Putative 3-oxoacyl-ACP synthase I		 sppA
SAV2838
SAV_2838		 Streptomyces avermitilis
90
 D8I4M1_AMYMU
(D8I4M1)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (419)
 2e-84 318   43% 3-oxoacyl-[acyl-carrier-protein] synthase II fabF
AMED_5435		 Amycolatopsis mediterranei (strain U-32)
91
 E8W952_STRFA
(E8W952)		 
[query] 2 - 418 (428)
[subject] 3 - 414 (423)
 2e-84 317   45% Beta-ketoacyl synthase Sfla_5318 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
92
 Q9FAR5_STRAU
(Q9FAR5)		 
[query] 2 - 418 (428)
[subject] 9 - 418 (427)
 3e-84 317   43% Beta-ketoacyl synthase tcsD Streptomyces aureofaciens
93
 A8M4V3_SALAI
(A8M4V3)		 
[query] 2 - 422 (428)
[subject] 4 - 418 (423)
 3e-84 317   44% Beta-ketoacyl synthase Sare_2684 Salinispora arenicola (strain CNS-205)
94
 Q54281_SACHI
(Q54281)		 
[query] 2 - 422 (428)
[subject] 3 - 417 (422)
 4e-84 316   41% Polyketide synthase Saccharopolyspora hirsuta
95
 A4X7U6_SALTO
(A4X7U6)		 
[query] 2 - 420 (428)
[subject] 4 - 416 (423)
 4e-84 316   45% 3-oxoacyl-[acyl-carrier-protein] synthase II Strop_2500 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) 2.3.1.41
96
 Q48375_KIBAR
(Q48375)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 5e-84 316   42% ArdIorf1 ardIorf1 Kibdelosporangium aridum
97
 D9UBR8_STRPR
(D9UBR8)		 
[query] 2 - 427 (428)
[subject] 5 - 424 (424)
 5e-84 316   43% Putative ketoacylsynthase, chain length factor alpha-subunit cpp16 Streptomyces pristinaespiralis 2.3.1.179
98
 B5HIV0_STRPR
(B5HIV0)		 
[query] 2 - 427 (428)
[subject] 5 - 424 (424)
 5e-84 316   43% Beta-ketoacylsynthase I SSDG_05087 Streptomyces pristinaespiralis ATCC 25486
99
 Q67G30_9ACTO
(Q67G30)		 Jump to Heda_00280 
[query] 2 - 418 (428)
[subject] 7 - 414 (422)
 7e-84 315   44% Putative keto synthase alpha Streptomyces griseoruber
100
 Q9AMJ3_STRAT
(Q9AMJ3)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 1e-83 315   41% Putative ketosynthase SimA1 simA1 Streptomyces antibioticus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q70DX2_9ACTO
(Q70DX2)		 
[query] 1 - 428 (428)
[subject] 1 - 428 (428)
 0.0 867   100%
Product
RemA protein
Gene
remA
Organism
Streptomyces resistomycificus
1uniprot[Pubmed] 14982421
A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns.(J. Am. Chem. Soc.) [2004]
5
 F4FBT7_VERMA
(F4FBT7)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (420)
 9e-97 358   47%
Product
3-oxoacyl-(Acyl-carrier-protein) synthase 2
Gene
VAB18032_18175
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
6
 F2RIV6_STRVP
(F2RIV6)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 1e-95 355   45%
Product
Polyketide beta-ketoacyl synthase WhiE-KS
Gene
SVEN_6796
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
8
 D2AY44_STRRD
(D2AY44)		 
[query] 2 - 424 (428)
[subject] 5 - 419 (422)
 2e-94 350   46%
Product
3-oxoacyl-(Acyl-carrier-protein) synthase II
Gene
Sros_4150
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
9
 KAS1_STRCN
(Q02578)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 4e-94 350   46%
Product
Putative polyketide beta-ketoacyl synthase 1
Gene
curA
Organism
Streptomyces cyaneus
Streptomyces curacoi
1uniprot[Pubmed] 1644304 [Medline] 92354925
Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces curacoi.(Gene) [1992]
13
 F3NHY3_9ACTO
(F3NHY3)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 6e-94 349   45%
Product
Polyketide beta-ketoacyl synthase alpha
Gene
SGM_2747
Organism
Streptomyces griseoaurantiacus M045
1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]
15
 B1GSN1_9ACTO
(B1GSN1)		 Jump to Bena_00090 
[query] 2 - 418 (428)
[subject] 5 - 415 (423)
 1e-93 348   44%
Product
BenA protein
Gene
benA
Organism
Streptomyces sp. A2991200
1uniprot[Pubmed] 17439117
Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007]
18
 KAS1_STRHA
(Q05356)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 3e-93 347   46%
Product
Putative polyketide beta-ketoacyl synthase 1
Polyketide condensing enzyme
Gene
sch1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 8344517 [Medline] 93345807
Hybridization and DNA sequence analyses suggest an early evolutionary divergence of related biosynthetic gene sets encoding polyketide antibiotics and spore pigments in Streptomyces spp.(Gene) [1993]
23
 Q54173_STRFR
(Q54173)		 Jump to Urd_00120 
[query] 2 - 418 (428)
[subject] 7 - 417 (426)
 4e-92 343   44%
Product
Putative ketoacyl synthase
Gene
UrdA
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
30
 C9Z5P4_STRSW
(C9Z5P4)		 
[query] 4 - 427 (428)
[subject] 1 - 418 (418)
 3e-90 337   43%
Product
Putative polyketide beta-ketoacyl synthase 1
Gene
sppA
SCAB_43301
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
33
 O68918_9ACTO
(O68918)		 Jump to Fren_00120 
[query] 2 - 426 (428)
[subject] 3 - 419 (425)
 6e-90 336   43%
Product
Ketoacyl synthase
Gene
frnL
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
34
 Q54994_9ACTO
(Q54994)		 
[query] 2 - 426 (428)
[subject] 3 - 419 (425)
 1e-89 335   43%
Product
Putative uncharacterized protein
Gene
 
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
35
 D9UBT2_STRPR
(D9UBT2)		 
[query] 1 - 418 (428)
[subject] 1 - 412 (422)
 1e-89 335   43%
Product
Putative ketoacylsynthase, chain length factor alpha-subunit
Gene
cpp3
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
39
 Q54217_STRGR
(Q54217)		 Jump to Griseu_00010 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 2e-89 334   45%
Product
Ketosynthase
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
40
 E2PVZ8_STRCL
(E2PVZ8)		 
[query] 21 - 428 (428)
[subject] 22 - 421 (422)
 3e-89 333   45%
Product
Putative polyketide beta-ketoacyl synthase 1
Gene
sppA
SCLAV_4915
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
41
 Q2PA07_9ACTO
(Q2PA07)		 Jump to Stref_00080 
[query] 2 - 420 (428)
[subject] 3 - 415 (422)
 5e-89 333   43%
Product
Ketoacyl synthase
Gene
stfP
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
42
 C0JWB4_9ACTO
(C0JWB4)		 Jump to Polk_00190 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 5e-89 332   44%
Product
PokP1
Gene
pokP1
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
43
 D7C2K2_STRBB
(D7C2K2)		 
[query] 2 - 418 (428)
[subject] 3 - 416 (424)
 5e-89 332   45%
Product
3-oxoacyl-ACP synthase I
Gene
sppA
SBI_02764
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
44
 O32451_9ACTO
(O32451)		 
[query] 2 - 420 (428)
[subject] 10 - 422 (425)
 9e-89 332   44%
Product
ORF 1
PdmA
Gene
pdmA
Organism
Actinomadura hibisca
1uniprot[Pubmed] 9339544 [Medline] 97480928
Cloning and nucleotide sequence of the putative polyketide synthase genes for pradimicin biosynthesis from Actinomadura hibisca.(Biosci. Biotechnol. Biochem.) [1997]
45
 C7N0D1_SACVD
(C7N0D1)		 
[query] 1 - 418 (428)
[subject] 1 - 413 (426)
 1e-88 332   42%
Product
3-oxoacyl-(Acyl-carrier-protein) synthase
Gene
Svir_33690
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
48
 B6SEF1_9ACTO
(B6SEF1)		 Jump to Alnu_00060 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 3e-88 330   43%
Product
AlnL ketoacyl synthase alpha
Gene
alnL
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
50
 KAS1_STRCO
(P23155)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 4e-88 330   44%
Product
Putative polyketide beta-ketoacyl synthase 1
WhiE ORF III
Gene
SCO5318
SC6G9.15
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 2077356 [Medline] 91171868
Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics.(Mol. Microbiol.) [1990]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
51
 Q0MRN5_9ACTO
(Q0MRN5)		 
[query] 1 - 418 (428)
[subject] 1 - 409 (421)
 4e-88 330   44%
Product
Putative beta-ketoacyl synthase
Gene
 
Organism
Streptomyces toxytricini
1uniprot[Pubmed] 17205043
Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.(J. Microbiol.) [2006]
52
 Q2J5J3_FRASC
(Q2J5J3)		 
[query] 2 - 428 (428)
[subject] 5 - 423 (424)
 6e-88 329   41%
Product
3-oxoacyl-[acyl-carrier-protein] synthase II
Gene
Francci3_4101
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
53
 Q2HR20_9ACTO
(Q2HR20)		 Jump to Sch475_00380 
[query] 5 - 418 (428)
[subject] 1 - 408 (420)
 7e-88 329   43%
Product
Putative ketoacyl synthase
Gene
schP8
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
54
 C7Q5R5_CATAD
(C7Q5R5)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 7e-88 329   44%
Product
Beta-ketoacyl synthase
Gene
Caci_1086
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
56
 Q54495_STRNO
(Q54495)		 Jump to Nogl_00370 
[query] 2 - 418 (428)
[subject] 7 - 418 (430)
 1e-87 328   44%
Product
Snoa1
Gene
snoa1
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
58
 Q6VMI7_STRAM
(Q6VMI7)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-87 328   44%
Product
Putative ketoacyl synthase
Gene
alpA
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
59
 Q1RQS0_STRAM
(Q1RQS0)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-87 328   44%
Product
Putative ketoacyl synthase
Gene
alpA
SAMT0165
SAMT0166
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
60
 Q8KSW4_9ACTO
(Q8KSW4)		 Jump to Griseo_00280 
[query] 2 - 418 (428)
[subject] 3 - 414 (426)
 2e-87 328   43%
Product
Putative ketosynthase alpha GrhA
Gene
grhA
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
62
 Q93LZ8_STRAU
(Q93LZ8)		 
[query] 2 - 425 (428)
[subject] 3 - 420 (423)
 2e-87 327   42%
Product
B-ketoacyl-ACP synthase-like protein
Gene
aur2A
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 15497441
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004]
63
 Q7MZT3_PHOLL
(Q7MZT3)		 
[query] 2 - 424 (428)
[subject] 12 - 427 (428)
 3e-87 327   42%
Product
Similar to polyketide beta-ketoacyl synthase
Gene
plu4191
Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
1uniprot[Pubmed] 14528314 [Medline] 22957627
The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens.(Nat. Biotechnol.) [2003]
65
 D5MRH6_9ACTO
(D5MRH6)		 
[query] 2 - 424 (428)
[subject] 4 - 421 (423)
 3e-87 327   43%
Product
Putative ketosynthase
Gene
hrbC
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
66
 Q56HA2_STRAU
(Q56HA2)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 3e-87 327   44%
Product
Aur1D
Gene
aur1D
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
68
 Q93LY4_9ACTO
(Q93LY4)		 
[query] 2 - 424 (428)
[subject] 3 - 420 (422)
 5e-87 326   42%
Product
Ketosynthase PgaA
Gene
pgaA
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
70
 E4NJ51_KITSK
(E4NJ51)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 9e-87 325   46%
Product
Putative 3-oxoacyl-[acyl-carrier-protein] synthase
Gene
KSE_72440
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
71
 Q83X35_STRRO
(Q83X35)		 
[query] 1 - 418 (428)
[subject] 1 - 411 (421)
 9e-87 325   43%
Product
Beta-ketoacyl synthase alpha-subunit
Gene
rocA
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
72
 E2EKJ9_9ACTO
(E2EKJ9)		 
[query] 5 - 423 (428)
[subject] 6 - 418 (421)
 2e-86 324   42%
Product
Ketosynthase
Gene
sanF
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
73
 Q9XE00_9ACTO
(Q9XE00)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 2e-86 324   43%
Product
Polyketide synthase
Gene
 
Organism
Actinomadura verrucosospora
1uniprot[Pubmed] 10347064 [Medline] 99278093
Development of a self-cloning system for Actinomadura verrucosospora and identification of polyketide synthase genes essential for production of the angucyclic antibiotic pradimicin.(Appl. Environ. Microbiol.) [1999]
74
 Q8VWB3_9ACTO
(Q8VWB3)		 
[query] 2 - 428 (428)
[subject] 4 - 423 (423)
 2e-86 324   44%
Product
AknB
Gene
aknB
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
75
 D5UC54_CELFN
(D5UC54)		 
[query] 1 - 418 (428)
[subject] 4 - 415 (422)
 2e-86 324   44%
Product
Beta-ketoacyl synthase
Gene
Cfla_3334
Organism
Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
1uniprot
Complete genome sequence of Cellulomonas flavigena type strain (134).(Stand. Genomic Sci.) [2010]
76
 Q9RHT8_STRRO
(Q9RHT8)		 
[query] 1 - 418 (428)
[subject] 1 - 409 (419)
 2e-86 324   44%
Product
Ketosynthase
Gene
orf1
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
78
 F4F9S3_VERMA
(F4F9S3)		 
[query] 2 - 422 (428)
[subject] 4 - 418 (424)
 3e-86 323   44%
Product
Beta-ketoacyl synthase
Gene
VAB18032_23755
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
79
 Q9F6E0_9ACTO
(Q9F6E0)		 Jump to R1128_00020 
[query] 5 - 427 (428)
[subject] 1 - 417 (417)
 6e-86 322   40%
Product
Beta-ketoacylsynthase I
Gene
zhuB
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
82
 Q0JWA1_STRAM
(Q0JWA1)		 
[query] 5 - 418 (428)
[subject] 1 - 408 (417)
 7e-86 322   44%
Product
Putative ketoacyl synthase
Gene
DSMT0185
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
83
 Q53671_STRAA
(Q53671)		 Jump to Mith_00140 
[query] 2 - 418 (428)
[subject] 3 - 412 (422)
 8e-86 322   43%
Product
Ketoacyl synthase
Gene
mtmP
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
85
 C4NYJ9_9ACTO
(C4NYJ9)		 
[query] 3 - 418 (428)
[subject] 4 - 413 (422)
 2e-85 321   44%
Product
SaqA
Gene
saqA
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
86
 Q9X461_STRAE
(Q9X461)		 Jump to Naphcy_00010 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 2e-85 321   42%
Product
Beta-ketoacyl synthase/acyl transferase
Gene
ncnA
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]
88
 Q9L551_9ACTO
(Q9L551)		 Jump to Acla_00070 
[query] 2 - 428 (428)
[subject] 4 - 423 (423)
 8e-85 318   43%
Product
AknB
Gene
aknB
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
89
 Q93HM2_STRAW
(Q93HM2)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (421)
 1e-84 318   43%
Product
3-oxoacyl-(Acyl carrier protein) synthase I
Putative 3-oxoacyl-ACP synthase I
Gene
sppA
SAV2838
SAV_2838
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
90
 D8I4M1_AMYMU
(D8I4M1)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (419)
 2e-84 318   43%
Product
3-oxoacyl-[acyl-carrier-protein] synthase II
Gene
fabF
AMED_5435
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
94
 Q54281_SACHI
(Q54281)		 
[query] 2 - 422 (428)
[subject] 3 - 417 (422)
 4e-84 316   41%
Product
Polyketide synthase
Gene
 
Organism
Saccharopolyspora hirsuta
1uniprot[Pubmed] 8341260 [Medline] 93341453
Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993]
96
 Q48375_KIBAR
(Q48375)		 
[query] 2 - 418 (428)
[subject] 4 - 414 (423)
 5e-84 316   42%
Product
ArdIorf1
Gene
ardIorf1
Organism
Kibdelosporangium aridum
1uniprot[Pubmed] 7987007 [Medline] 95078455
Cloning and nucleotide sequence of a region of the Kibdelosporangium aridum genome homologous to polyketide biosynthetic genes.(DNA Seq.) [1994]
97
 D9UBR8_STRPR
(D9UBR8)		 
[query] 2 - 427 (428)
[subject] 5 - 424 (424)
 5e-84 316   43%
Product
Putative ketoacylsynthase, chain length factor alpha-subunit
Gene
cpp16
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
99
 Q67G30_9ACTO
(Q67G30)		 Jump to Heda_00280 
[query] 2 - 418 (428)
[subject] 7 - 414 (422)
 7e-84 315   44%
Product
Putative keto synthase alpha
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
100
 Q9AMJ3_STRAT
(Q9AMJ3)		 
[query] 2 - 418 (428)
[subject] 3 - 413 (422)
 1e-83 315   41%
Product
Putative ketosynthase SimA1
Gene
simA1
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]