BLAST table : Lydi_00140

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q52V50_9ACTO
(Q52V50)		 
[query] 35 - 5648 (5648)
[subject] 1834 - 7510 (7510)
(5 hsp)		 0.0 5695   58% Polyketide synthase type I Streptomyces aizunensis
2
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 27 - 5565 (5648)
[subject] 1759 - 7196 (7488)
(7 hsp)		 0.0 5339   56% ObsC Saccharopolyspora spinosa
3
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 5578 (5648)
[subject] 3501 - 9074 (10917)
(9 hsp)		 0.0 5300   56% AmphC amphC Streptomyces nodosus
4
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 35 - 5567 (5648)
[subject] 3501 - 9195 (11096)
(10 hsp)		 0.0 5122   54% NysC nysC Streptomyces noursei
5
 D7C2B8_STRBB
(D7C2B8)		 
[query] 39 - 5194 (5648)
[subject] 1581 - 6726 (7498)
(12 hsp)		 0.0 5048   56% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
6
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 5647 (5648)
[subject] 137 - 5825 (5826)
(5 hsp)		 0.0 5031   52% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
7
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 35 - 5567 (5648)
[subject] 3524 - 9029 (10876)
(10 hsp)		 0.0 5021   55% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
8
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 4 - 5646 (5648)
[subject] 3 - 5629 (5630)
 0.0 4907   51% Polyketide synthase tsnAIII Streptomyces longisporoflavus
9
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1 - 5644 (5648)
[subject] 5 - 5818 (5822)
 0.0 4888   51% Modular polyketide synthase meiA3 Streptomyces nanchangensis
10
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 4 - 5646 (5648)
[subject] 3 - 5714 (5718)
 0.0 4885   50% ChlA3 Streptomyces antibioticus
11
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 19 - 5614 (5648)
[subject] 15 - 5622 (5657)
 0.0 4678   49% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
12
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 5569 (5648)
[subject] 3263 - 8490 (10223)
(8 hsp)		 0.0 4615   51% Polyketide synthase rapB Streptomyces hygroscopicus
13
 A8J704_9ACTO
(A8J704)		 
[query] 1 - 5647 (5648)
[subject] 1 - 5673 (5674)
 0.0 4529   50% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
14
 E3JBU2_FRASU
(E3JBU2)		 
[query] 32 - 5562 (5648)
[subject] 1810 - 7602 (7679)
(8 hsp)		 0.0 4370   49% Acyl transferase FraEuI1c_4253 Frankia sp. (strain EuI1c)
15
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 35 - 4733 (5648)
[subject] 2109 - 6698 (7620)
(11 hsp)		 0.0 4358   54% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
16
 A4FH83_SACEN
(A4FH83)		 
[query] 4 - 4762 (5648)
[subject] 3 - 4689 (5359)
(7 hsp)		 0.0 4347   54% Type I modular polyketide synthase SACE_4139 Saccharopolyspora erythraea (strain NRRL 23338)
17
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 4 - 4762 (5648)
[subject] 3 - 4689 (5359)
(7 hsp)		 0.0 4347   54% Type I PKS pkeAIII Saccharopolyspora erythraea
Streptomyces erythraeus
18
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 35 - 4733 (5648)
[subject] 2067 - 6654 (7576)
(11 hsp)		 0.0 4342   54% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
19
 D9T6W3_MICAI
(D9T6W3)		 
[query] 35 - 4721 (5648)
[subject] 2101 - 6800 (7520)
(11 hsp)		 0.0 4169   53% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
20
 E8S0C6_MICSL
(E8S0C6)		 
[query] 35 - 4721 (5648)
[subject] 2101 - 6800 (7520)
(12 hsp)		 0.0 4159   54% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
21
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 30 - 5194 (5648)
[subject] 3617 - 8958 (16990)
(18 hsp)		 0.0 4058   47% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
22
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 35 - 5196 (5648)
[subject] 1308 - 6157 (8563)
(13 hsp)		 0.0 4053   49% Polyketide synthase rapA Streptomyces hygroscopicus
23
 E0L044_STRVO
(E0L044)		 
[query] 1728 - 5636 (5648)
[subject] 3232 - 7203 (7224)
(8 hsp)		 0.0 4008   58% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
24
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 35 - 5553 (5648)
[subject] 1217 - 6238 (7938)
(10 hsp)		 0.0 3942   47% Polyketide synthase rapA Actinoplanes sp. N902-109
25
 A4X8L0_SALTO
(A4X8L0)		 
[query] 1734 - 5648 (5648)
[subject] 3270 - 7209 (7210)
(9 hsp)		 0.0 3799   56% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
26
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 3 - 3836 (5648)
[subject] 1 - 3869 (3936)
(3 hsp)		 0.0 3760   55% ChlA5 Streptomyces antibioticus
27
 Q52V53_9ACTO
(Q52V53)		 
[query] 1734 - 5648 (5648)
[subject] 1221 - 5207 (5207)
(9 hsp)		 0.0 3711   55% Polyketide synthase type I Streptomyces aizunensis
28
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1707 - 5648 (5648)
[subject] 3876 - 7746 (7746)
(12 hsp)		 0.0 3686   55% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
29
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 4 - 5029 (5648)
[subject] 3 - 4588 (6396)
(12 hsp)		 0.0 3684   47% FkbA fkbA Streptomyces hygroscopicus subsp. ascomyceticus
30
 Q52V52_9ACTO
(Q52V52)		 
[query] 1732 - 5648 (5648)
[subject] 1423 - 5432 (5432)
(6 hsp)		 0.0 3681   56% Polyketide synthase type I Streptomyces aizunensis
31
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 35 - 3855 (5648)
[subject] 3277 - 7047 (7102)
(11 hsp)		 0.0 3653   56% Polyketide synthase merB Streptomyces sp. NRRL 30748
32
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 35 - 3831 (5648)
[subject] 3322 - 7100 (7178)
(11 hsp)		 0.0 3644   56% MerB merB Streptomyces violaceoniger
33
 E9KTB8_STRKN
(E9KTB8)		 
[query] 4 - 5039 (5648)
[subject] 3 - 4617 (6408)
(11 hsp)		 0.0 3643   47% Polyketide synthase fkbA
Tcs_SK_034		 Streptomyces kanamyceticus
34
 E0KRC7_STRVO
(E0KRC7)		 
[query] 35 - 3831 (5648)
[subject] 1731 - 5481 (5559)
(10 hsp)		 0.0 3639   56% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
35
 D7BRD4_STRBB
(D7BRD4)		 
[query] 1732 - 5648 (5648)
[subject] 5970 - 9950 (9950)
(13 hsp)		 0.0 3621   54% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
36
 P95814_STRSQ
(P95814)		 
[query] 4 - 5026 (5648)
[subject] 3 - 4618 (6420)
(12 hsp)		 0.0 3615   46% FK506 polyketide synthase fkbA Streptomyces sp
37
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1759 - 5645 (5648)
[subject] 3256 - 7106 (7110)
(8 hsp)		 0.0 3611   55% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
38
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 1 - 3828 (5648)
[subject] 1 - 3870 (3896)
(4 hsp)		 0.0 3606   53% GdmAIII gdmAIII Streptomyces hygroscopicus
39
 B4VB11_9ACTO
(B4VB11)		 
[query] 1789 - 5618 (5648)
[subject] 1 - 3894 (3928)
(5 hsp)		 0.0 3603   56% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
40
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 1 - 3828 (5648)
[subject] 1 - 3862 (3888)
(4 hsp)		 0.0 3600   53% GelC Streptomyces hygroscopicus subsp. duamyceticus
41
 F1D8Z9_9ACTO
(F1D8Z9)		 
[query] 4 - 5026 (5648)
[subject] 3 - 4602 (6418)
(12 hsp)		 0.0 3589   47% FkbA Streptomyces sp. MJM7001
42
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1732 - 5648 (5648)
[subject] 2957 - 6831 (6831)
(9 hsp)		 0.0 3588   54% ScnS1 scnS1 Streptomyces chattanoogensis
43
 F1CT53_9ACTO
(F1CT53)		 
[query] 1 - 3847 (5648)
[subject] 1 - 3867 (3872)
(5 hsp)		 0.0 3586   53% GdmAIII gdmAIII Streptomyces autolyticus
44
 Q93H87_STRAW
(Q93H87)		 
[query] 1732 - 5648 (5648)
[subject] 2175 - 6048 (6048)
(11 hsp)		 0.0 3582   54% Modular polyketide synthase pteA1 Streptomyces avermitilis
45
 Q49BD9_STRHY
(Q49BD9)		 Jump to Herb_00190 
[query] 1 - 3828 (5648)
[subject] 1 - 3862 (3868)
(4 hsp)		 0.0 3576   53% HbmAIII hbmAIII Streptomyces hygroscopicus
46
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1733 - 5644 (5648)
[subject] 1351 - 5176 (5176)
(6 hsp)		 0.0 3573   54% ObsB Saccharopolyspora spinosa
47
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 4 - 5026 (5648)
[subject] 3 - 4602 (6418)
(12 hsp)		 0.0 3569   46% Polyketide synthase fkbA
Tcs_11604BP_031		 Streptomyces sp. KCTC 11604BP
48
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1732 - 5646 (5648)
[subject] 1405 - 5337 (5339)
(6 hsp)		 0.0 3568   53% Polyketide synthase natB Streptomyces sp. CS
49
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1733 - 5648 (5648)
[subject] 1324 - 5099 (5099)
(8 hsp)		 0.0 3562   55% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
50
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1748 - 5648 (5648)
[subject] 2942 - 6797 (6797)
(9 hsp)		 0.0 3550   54% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
51
 E0KLD7_STRVO
(E0KLD7)		 
[query] 1 - 3834 (5648)
[subject] 1 - 3867 (3867)
(4 hsp)		 0.0 3536   52% (Acyl-carrier-protein) S-malonyltransferase., 6-deoxyerythronolide-B synthase StrviDRAFT_3410 Streptomyces violaceusniger Tu 4113 2.3.1.39

2.3.1.94
52
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 1728 - 5565 (5648)
[subject] 1341 - 5076 (5157)
(8 hsp)		 0.0 3506   55% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
53
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1750 - 5646 (5648)
[subject] 1409 - 5320 (5321)
(6 hsp)		 0.0 3502   54% Polyketide synthase natC Streptomyces sp. CS
54
 E8S0C5_MICSL
(E8S0C5)		 
[query] 1744 - 5574 (5648)
[subject] 2988 - 6828 (9937)
(18 hsp)		 0.0 3491   54% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
55
 E0L075_STRVO
(E0L075)		 
[query] 35 - 3344 (5648)
[subject] 1801 - 5128 (5786)
(11 hsp)		 0.0 3490   58% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
56
 D9T6W4_MICAI
(D9T6W4)		 
[query] 1744 - 5574 (5648)
[subject] 2988 - 6828 (9936)
(18 hsp)		 0.0 3484   54% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
57
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 2109 - 5646 (5648)
[subject] 34 - 3582 (3582)
(4 hsp)		 0.0 3484   56% LipPks2 lipPks2 Streptomyces aureofaciens
58
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 2107 - 5567 (5648)
[subject] 17 - 3479 (4894)
(6 hsp)		 0.0 3457   56% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
59
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1748 - 5567 (5648)
[subject] 1431 - 5236 (10625)
(13 hsp)		 0.0 3454   54% FscC fscC Streptomyces sp. FR-008
60
 E8WEN5_STRFA
(E8WEN5)		 
[query] 1728 - 5565 (5648)
[subject] 1343 - 5075 (5156)
(5 hsp)		 0.0 3453   54% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
61
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 30 - 3491 (5648)
[subject] 1652 - 4981 (5723)
(10 hsp)		 0.0 3438   58% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
62
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1724 - 5565 (5648)
[subject] 2216 - 5974 (6078)
(10 hsp)		 0.0 3426   54% ObsA Saccharopolyspora spinosa
63
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 2105 - 5568 (5648)
[subject] 30 - 3537 (3612)
(5 hsp)		 0.0 3410   55% LipPks3 lipPks3 Streptomyces aureofaciens
64
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1730 - 5646 (5648)
[subject] 2386 - 6239 (6241)
(9 hsp)		 0.0 3407   53% Polyketide synthase KijS1 Actinomadura kijaniata
65
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1735 - 5648 (5648)
[subject] 2410 - 6383 (6383)
(11 hsp)		 0.0 3403   50% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
66
 C0Z473_STRVN
(C0Z473)		 
[query] 20 - 3828 (5648)
[subject] 2 - 3859 (3973)
(3 hsp)		 0.0 3388   54% Type I polyketide synthase, modules 4-5 ken12 Streptomyces violaceoruber
67
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1728 - 5565 (5648)
[subject] 1398 - 5290 (5588)
(7 hsp)		 0.0 3383   52% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
68
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 10 - 3824 (5648)
[subject] 15 - 3842 (3921)
(4 hsp)		 0.0 3383   53% Polyketide synthase KijS4 Actinomadura kijaniata
69
 B5L6M3_MICCH
(B5L6M3)		 
[query] 12 - 3829 (5648)
[subject] 17 - 3874 (3953)
(3 hsp)		 0.0 3372   52% Putative type I polyketide synthase Micromonospora chalcea
70
 Q52V49_9ACTO
(Q52V49)		 
[query] 2100 - 5567 (5648)
[subject] 24 - 3579 (3872)
(6 hsp)		 0.0 3367   56% Polyketide synthase type I Streptomyces aizunensis
71
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1733 - 5648 (5648)
[subject] 1206 - 5219 (5220)
(7 hsp)		 0.0 3360   51% Type I polyketide synthase hlsC Streptomyces halstedii
72
 Q0QMN5_9ACTO
(Q0QMN5)		 
[query] 635 - 4731 (5648)
[subject] 681 - 4712 (5393)
(11 hsp)		 0.0 3359   51% Polyketide synthase type I Streptomyces sp. Eco86
73
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1734 - 5565 (5648)
[subject] 1367 - 5110 (5400)
(6 hsp)		 0.0 3356   54% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
74
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 1713 - 5565 (5648)
[subject] 1428 - 5215 (5260)
(7 hsp)		 0.0 3319   52% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
75
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 35 - 3828 (5648)
[subject] 1798 - 5559 (5644)
(6 hsp)		 0.0 3318   52% AmphJ amphJ Streptomyces nodosus
76
 F8K324_STRCT
(F8K324)		 
[query] 4 - 3828 (5648)
[subject] 3 - 3849 (3931)
(3 hsp)		 0.0 3318   51% Polyketide synthase type I (Modular protein) SCAT_0140 Streptomyces cattleya
77
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 1750 - 5563 (5648)
[subject] 219 - 4010 (5945)
(10 hsp)		 0.0 3297   53% Polyketide synthase SSHG_00090 Streptomyces albus J1074
78
 D7F1M2_9ACTO
(D7F1M2)		 
[query] 32 - 3829 (5648)
[subject] 2136 - 5942 (6036)
(6 hsp)		 0.0 3271   50% Polyketide synthase tsnAIV Streptomyces longisporoflavus
79
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 1989 - 5646 (5648)
[subject] 967 - 4697 (4699)
(8 hsp)		 0.0 3267   52% ChlA1 Streptomyces antibioticus
80
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2109 - 5565 (5648)
[subject] 37 - 3294 (3377)
(5 hsp)		 0.0 3263   55% Polyketide synthase type I becF Streptomyces sp. DSM 21069
81
 B5A9Q1_9PSEU
(B5A9Q1)		 
[query] 6 - 3833 (5648)
[subject] 14 - 3837 (3874)
(4 hsp)		 0.0 3262   52% MbcAIII mbcAIII Actinosynnema pretiosum subsp. pretiosum
82
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1732 - 5566 (5648)
[subject] 3099 - 6934 (7007)
(10 hsp)		 0.0 3260   51% Putative type I polyketide synthase Micromonospora chalcea
83
 E8WEN9_STRFA
(E8WEN9)		 
[query] 2081 - 5647 (5648)
[subject] 8 - 3509 (3511)
(4 hsp)		 0.0 3257   55% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
84
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2109 - 5565 (5648)
[subject] 37 - 3291 (3373)
(5 hsp)		 0.0 3244   54% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
85
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 30 - 3828 (5648)
[subject] 1593 - 5460 (5541)
(8 hsp)		 0.0 3241   52% FscB fscB Streptomyces sp. FR-008
86
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 2010 - 5567 (5648)
[subject] 886 - 4325 (5113)
(12 hsp)		 0.0 3238   54% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
87
 C6W8U9_ACTMD
(C6W8U9)		 
[query] 6 - 3833 (5648)
[subject] 14 - 3837 (3874)
(4 hsp)		 0.0 3235   52% Short-chain dehydrogenase/reductase SDR Amir_3292 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
88
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1727 - 5623 (5648)
[subject] 1375 - 5234 (5255)
(5 hsp)		 0.0 3229   52% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
89
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 2082 - 5574 (5648)
[subject] 11 - 3503 (3799)
(5 hsp)		 0.0 3229   54% Polyketide synthase gfsE Streptomyces graminofaciens
90
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 1728 - 5570 (5648)
[subject] 3759 - 7447 (9528)
(17 hsp)		 0.0 3226   52% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
91
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 2109 - 5646 (5648)
[subject] 36 - 3590 (3596)
(5 hsp)		 0.0 3223   53% Polyketide synthase idmM Streptomyces antibioticus
92
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 1728 - 5570 (5648)
[subject] 3875 - 7567 (9648)
(17 hsp)		 0.0 3221   52% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
93
 Q1MX72_9ACTO
(Q1MX72)		 Jump to Tetrn_00170 
[query] 30 - 3840 (5648)
[subject] 2097 - 5882 (5963)
(7 hsp)		 0.0 3213   50% Type I polyketide synthase tmnAV Streptomyces sp. NRRL 11266
94
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 1727 - 5565 (5648)
[subject] 3418 - 7180 (10827)
(18 hsp)		 0.0 3211   52% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
95
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1708 - 5566 (5648)
[subject] 1321 - 5006 (5060)
(7 hsp)		 0.0 3204   51% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
96
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1708 - 5566 (5648)
[subject] 1321 - 5006 (5060)
(7 hsp)		 0.0 3204   51% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
97
 O52789_AMYMD
(O52789)		 
[query] 1708 - 5566 (5648)
[subject] 1330 - 5015 (5069)
(7 hsp)		 0.0 3200   51% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
98
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 2077 - 5568 (5648)
[subject] 3 - 3600 (5232)
(8 hsp)		 0.0 3197   53% Type I polyketide synthase hlsF Streptomyces halstedii
99
 D0LQW2_HALO1
(D0LQW2)		 
[query] 13 - 3832 (5648)
[subject] 5 - 3849 (3930)
(3 hsp)		 0.0 3196   48% KR domain protein Hoch_2956 Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)
100
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1732 - 5600 (5648)
[subject] 4518 - 8257 (8301)
(12 hsp)		 0.0 3192   52% Type I polyketide synthase sfaH Streptomyces flaveolus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q52V50_9ACTO
(Q52V50)		 
[query] 35 - 5648 (5648)
[subject] 1834 - 7510 (7510)
(5 hsp)		 0.0 5695   58%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
2
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 27 - 5565 (5648)
[subject] 1759 - 7196 (7488)
(7 hsp)		 0.0 5339   56%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
3
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 5578 (5648)
[subject] 3501 - 9074 (10917)
(9 hsp)		 0.0 5300   56%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
4
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 35 - 5567 (5648)
[subject] 3501 - 9195 (11096)
(10 hsp)		 0.0 5122   54%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
5
 D7C2B8_STRBB
(D7C2B8)		 
[query] 39 - 5194 (5648)
[subject] 1581 - 6726 (7498)
(12 hsp)		 0.0 5048   56%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 5647 (5648)
[subject] 137 - 5825 (5826)
(5 hsp)		 0.0 5031   52%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
7
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 35 - 5567 (5648)
[subject] 3524 - 9029 (10876)
(10 hsp)		 0.0 5021   55%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
9
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1 - 5644 (5648)
[subject] 5 - 5818 (5822)
 0.0 4888   51%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
10
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 4 - 5646 (5648)
[subject] 3 - 5714 (5718)
 0.0 4885   50%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
12
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 5569 (5648)
[subject] 3263 - 8490 (10223)
(8 hsp)		 0.0 4615   51%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
15
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 35 - 4733 (5648)
[subject] 2109 - 6698 (7620)
(11 hsp)		 0.0 4358   54%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
16
 A4FH83_SACEN
(A4FH83)		 
[query] 4 - 4762 (5648)
[subject] 3 - 4689 (5359)
(7 hsp)		 0.0 4347   54%
Product
Type I modular polyketide synthase
Gene
SACE_4139
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
17
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 4 - 4762 (5648)
[subject] 3 - 4689 (5359)
(7 hsp)		 0.0 4347   54%
Product
Type I PKS
Gene
pkeAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
18
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 35 - 4733 (5648)
[subject] 2067 - 6654 (7576)
(11 hsp)		 0.0 4342   54%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
21
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 30 - 5194 (5648)
[subject] 3617 - 8958 (16990)
(18 hsp)		 0.0 4058   47%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
22
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 35 - 5196 (5648)
[subject] 1308 - 6157 (8563)
(13 hsp)		 0.0 4053   49%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
26
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 3 - 3836 (5648)
[subject] 1 - 3869 (3936)
(3 hsp)		 0.0 3760   55%
Product
ChlA5
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
27
 Q52V53_9ACTO
(Q52V53)		 
[query] 1734 - 5648 (5648)
[subject] 1221 - 5207 (5207)
(9 hsp)		 0.0 3711   55%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
28
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1707 - 5648 (5648)
[subject] 3876 - 7746 (7746)
(12 hsp)		 0.0 3686   55%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
29
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 4 - 5029 (5648)
[subject] 3 - 4588 (6396)
(12 hsp)		 0.0 3684   47%
Product
FkbA
Gene
fkbA
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
30
 Q52V52_9ACTO
(Q52V52)		 
[query] 1732 - 5648 (5648)
[subject] 1423 - 5432 (5432)
(6 hsp)		 0.0 3681   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
31
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 35 - 3855 (5648)
[subject] 3277 - 7047 (7102)
(11 hsp)		 0.0 3653   56%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
32
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 35 - 3831 (5648)
[subject] 3322 - 7100 (7178)
(11 hsp)		 0.0 3644   56%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
33
 E9KTB8_STRKN
(E9KTB8)		 
[query] 4 - 5039 (5648)
[subject] 3 - 4617 (6408)
(11 hsp)		 0.0 3643   47%
Product
Polyketide synthase
Gene
fkbA
Tcs_SK_034
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
35
 D7BRD4_STRBB
(D7BRD4)		 
[query] 1732 - 5648 (5648)
[subject] 5970 - 9950 (9950)
(13 hsp)		 0.0 3621   54%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
36
 P95814_STRSQ
(P95814)		 
[query] 4 - 5026 (5648)
[subject] 3 - 4618 (6420)
(12 hsp)		 0.0 3615   46%
Product
FK506 polyketide synthase
Gene
fkbA
Organism
Streptomyces sp
1uniprot[Pubmed] 9063448 [Medline] 97217427
Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506.(Eur. J. Biochem.) [1997]
37
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1759 - 5645 (5648)
[subject] 3256 - 7106 (7110)
(8 hsp)		 0.0 3611   55%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
38
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 1 - 3828 (5648)
[subject] 1 - 3870 (3896)
(4 hsp)		 0.0 3606   53%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
40
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 1 - 3828 (5648)
[subject] 1 - 3862 (3888)
(4 hsp)		 0.0 3600   53%
Product
GelC
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
42
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1732 - 5648 (5648)
[subject] 2957 - 6831 (6831)
(9 hsp)		 0.0 3588   54%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
43
 F1CT53_9ACTO
(F1CT53)		 
[query] 1 - 3847 (5648)
[subject] 1 - 3867 (3872)
(5 hsp)		 0.0 3586   53%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
44
 Q93H87_STRAW
(Q93H87)		 
[query] 1732 - 5648 (5648)
[subject] 2175 - 6048 (6048)
(11 hsp)		 0.0 3582   54%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
45
 Q49BD9_STRHY
(Q49BD9)		 Jump to Herb_00190 
[query] 1 - 3828 (5648)
[subject] 1 - 3862 (3868)
(4 hsp)		 0.0 3576   53%
Product
HbmAIII
Gene
hbmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
46
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1733 - 5644 (5648)
[subject] 1351 - 5176 (5176)
(6 hsp)		 0.0 3573   54%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
47
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 4 - 5026 (5648)
[subject] 3 - 4602 (6418)
(12 hsp)		 0.0 3569   46%
Product
Polyketide synthase
Gene
fkbA
Tcs_11604BP_031
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
48
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1732 - 5646 (5648)
[subject] 1405 - 5337 (5339)
(6 hsp)		 0.0 3568   53%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
49
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1733 - 5648 (5648)
[subject] 1324 - 5099 (5099)
(8 hsp)		 0.0 3562   55%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
50
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1748 - 5648 (5648)
[subject] 2942 - 6797 (6797)
(9 hsp)		 0.0 3550   54%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
53
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1750 - 5646 (5648)
[subject] 1409 - 5320 (5321)
(6 hsp)		 0.0 3502   54%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
57
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 2109 - 5646 (5648)
[subject] 34 - 3582 (3582)
(4 hsp)		 0.0 3484   56%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
59
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1748 - 5567 (5648)
[subject] 1431 - 5236 (10625)
(13 hsp)		 0.0 3454   54%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
61
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 30 - 3491 (5648)
[subject] 1652 - 4981 (5723)
(10 hsp)		 0.0 3438   58%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
62
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1724 - 5565 (5648)
[subject] 2216 - 5974 (6078)
(10 hsp)		 0.0 3426   54%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
63
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 2105 - 5568 (5648)
[subject] 30 - 3537 (3612)
(5 hsp)		 0.0 3410   55%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
64
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1730 - 5646 (5648)
[subject] 2386 - 6239 (6241)
(9 hsp)		 0.0 3407   53%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
65
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1735 - 5648 (5648)
[subject] 2410 - 6383 (6383)
(11 hsp)		 0.0 3403   50%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
67
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1728 - 5565 (5648)
[subject] 1398 - 5290 (5588)
(7 hsp)		 0.0 3383   52%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
68
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 10 - 3824 (5648)
[subject] 15 - 3842 (3921)
(4 hsp)		 0.0 3383   53%
Product
Polyketide synthase
Gene
KijS4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
69
 B5L6M3_MICCH
(B5L6M3)		 
[query] 12 - 3829 (5648)
[subject] 17 - 3874 (3953)
(3 hsp)		 0.0 3372   52%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
70
 Q52V49_9ACTO
(Q52V49)		 
[query] 2100 - 5567 (5648)
[subject] 24 - 3579 (3872)
(6 hsp)		 0.0 3367   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
72
 Q0QMN5_9ACTO
(Q0QMN5)		 
[query] 635 - 4731 (5648)
[subject] 681 - 4712 (5393)
(11 hsp)		 0.0 3359   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces sp. Eco86
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
73
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1734 - 5565 (5648)
[subject] 1367 - 5110 (5400)
(6 hsp)		 0.0 3356   54%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
75
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 35 - 3828 (5648)
[subject] 1798 - 5559 (5644)
(6 hsp)		 0.0 3318   52%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
79
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 1989 - 5646 (5648)
[subject] 967 - 4697 (4699)
(8 hsp)		 0.0 3267   52%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
80
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2109 - 5565 (5648)
[subject] 37 - 3294 (3377)
(5 hsp)		 0.0 3263   55%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
82
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1732 - 5566 (5648)
[subject] 3099 - 6934 (7007)
(10 hsp)		 0.0 3260   51%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
84
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2109 - 5565 (5648)
[subject] 37 - 3291 (3373)
(5 hsp)		 0.0 3244   54%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
85
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 30 - 3828 (5648)
[subject] 1593 - 5460 (5541)
(8 hsp)		 0.0 3241   52%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
87
 C6W8U9_ACTMD
(C6W8U9)		 
[query] 6 - 3833 (5648)
[subject] 14 - 3837 (3874)
(4 hsp)		 0.0 3235   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_3292
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
89
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 2082 - 5574 (5648)
[subject] 11 - 3503 (3799)
(5 hsp)		 0.0 3229   54%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
90
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 1728 - 5570 (5648)
[subject] 3759 - 7447 (9528)
(17 hsp)		 0.0 3226   52%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
91
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 2109 - 5646 (5648)
[subject] 36 - 3590 (3596)
(5 hsp)		 0.0 3223   53%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
92
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 1728 - 5570 (5648)
[subject] 3875 - 7567 (9648)
(17 hsp)		 0.0 3221   52%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
94
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 1727 - 5565 (5648)
[subject] 3418 - 7180 (10827)
(18 hsp)		 0.0 3211   52%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
95
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1708 - 5566 (5648)
[subject] 1321 - 5006 (5060)
(7 hsp)		 0.0 3204   51%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
96
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1708 - 5566 (5648)
[subject] 1321 - 5006 (5060)
(7 hsp)		 0.0 3204   51%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
100
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1732 - 5600 (5648)
[subject] 4518 - 8257 (8301)
(12 hsp)		 0.0 3192   52%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]