Acid resistance (by GABA antiporter)(NFUNC_0071) |
必須 | A | GAD (NRULE_0231) | Glutamate decarboxylase | HMPREF0693_0980 |
GADC (NRULE_0234) | Glutamate/gamma-aminobutyrate antiporter | HMPREF0693_0979 |
Alanine racemization(NFUNC_0063) |
必須 | A | ALR (NRULE_0228) | Alanine racemase | HMPREF0693_1085 HMPREF0693_1417 HMPREF0693_2890 |
Aminoglycoside resistance (by aminoglycoside O-nucleotidyltransferase)(NFUNC_0042) |
必須 | A | ANT6 (NRULE_0151) | Aminoglycoside 6-adenylyltransferase | HMPREF0693_1939 |
Anthranilate biosynthesis(NFUNC_0038) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | HMPREF0693_0913 HMPREF0693_0460 |
TRPE (NRULE_0143) | Anthranilate synthase component I | HMPREF0693_0912 |
Aromatic azo compounds degradation(NFUNC_0073) |
必須 | A | AZOR (NRULE_0236) | FMN-dependent NADH-azoreductase | HMPREF0693_0741 |
Arsenical resistance(NFUNC_0004) |
必須 | A | ARSB1 (NRULE_0015) | Arsenical pump membrane protein | HMPREF0693_1786 |
ARSC1 (NRULE_0017) | Arsenate reductase | HMPREF0693_1195 |
Betaine biosynthesis (from choline)(NFUNC_0049) |
必須 | A | BETA (NRULE_0175) | Choline dehydrogenase | HMPREF0693_1034 |
Biotin biosynthesis(NFUNC_0051) |
必須 | A | BIOF (NRULE_0182) | 8-amino-7-oxononanoate synthase | HMPREF0693_1957 |
BIOA (NRULE_0183) | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | HMPREF0693_1955 |
BIOD (NRULE_0184) | ATP-dependent dethiobiotin synthetase BioD | HMPREF0693_1959 HMPREF0693_0865 |
BIOB (NRULE_0185) | Biotin synthase | HMPREF0693_1956 |
Chloramphenicol resistance(NFUNC_0025) |
必須 | A | CAT1 (NRULE_0107) | Chloramphenicol acetyltransferase | HMPREF0693_2081 |
Folate biosynthesis(NFUNC_0044) |
必須 | B | GLAT (NRULE_0142) | Glutamine amidotransferase | HMPREF0693_0913 HMPREF0693_0460 |
DHPS (NRULE_0144) | Dihydropteroate synthase | HMPREF0693_2341 |
FOLA (NRULE_0147) | Dihydrofolate reductase | HMPREF0693_2551 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | HMPREF0693_2573 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | HMPREF0693_3254 |
FOLC (NRULE_0160) | Bifunctional protein FolC | HMPREF0693_1429 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | HMPREF0693_1233 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | HMPREF0693_2994 |
GABA biosynthesis(NFUNC_0066) |
必須 | A | GAD (NRULE_0231) | Glutamate decarboxylase | HMPREF0693_0980 |
Macrolide antibiotic resistance(NFUNC_0045) |
必須 | B | RLMA (NRULE_0165) | 23S rRNA (guanine-N(1))-methyltransferase | HMPREF0693_1237 |
Metal-binding protein(NFUNC_0105) |
必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | HMPREF0693_1952 HMPREF0693_1948 |
B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | HMPREF0693_1948 |
C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | HMPREF0693_1116 HMPREF0693_3261 HMPREF0693_2620 HMPREF0693_1950 HMPREF0693_1480 |
E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | HMPREF0693_1812 HMPREF0693_1693 |
F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | HMPREF0693_2852 |
G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR | HMPREF0693_0214 |
I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | HMPREF0693_1507 |
Molybdate transport (ABC transporter)(NFUNC_0097) |
必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | HMPREF0693_1116 HMPREF0693_3261 HMPREF0693_2620 HMPREF0693_1950 HMPREF0693_1480 |
任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | HMPREF0693_1948 |
| MODB (NRULE_0325) | Molybdate ABC transporter permease protein | HMPREF0693_1951 |
| MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | HMPREF0693_1952 |
(R)-pantothenate biosynthesis(NFUNC_0030) |
必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | HMPREF0693_3257 |
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | HMPREF0693_3255 |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | HMPREF0693_3349 |
PANC (NRULE_0118) | Pantothenate synthetase | HMPREF0693_3256 |
Polymyxin resistance(NFUNC_0036) |
必須 | A | ARNA (NRULE_0132) | Bifunctional polymyxin resistance protein ArnA | HMPREF0693_0618 |
ARNB (NRULE_0133) | UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase | HMPREF0693_0616 |
ARNC (NRULE_0134) | Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase | HMPREF0693_0617 |
ARND (NRULE_0135) | Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | HMPREF0693_0619 |
ARNE (NRULE_0136) | Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE | HMPREF0693_0621 |
ARNF (NRULE_0137) | Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF | HMPREF0693_0622 |
ARNT (NRULE_0138) | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | HMPREF0693_0620 HMPREF0693_3176 |
Riboflavin biosynthesis(NFUNC_0058) |
必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | HMPREF0693_2566 |
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | HMPREF0693_0892 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | HMPREF0693_3369 |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | HMPREF0693_3368 |
RIBE (NRULE_0204) | Riboflavin synthase | HMPREF0693_0975 |
任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | HMPREF0693_3434 |
Streptomycin resistance(NFUNC_0054) |
必須 | A | ANT6 (NRULE_0151) | Aminoglycoside 6-adenylyltransferase | HMPREF0693_1939 |
Uptake of osmoprotectant(NFUNC_0061) |
必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | HMPREF0693_3765 |
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | HMPREF0693_3764 |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | HMPREF0693_3763 |
C | BCCT (NRULE_0220) | BCCT family transporter | HMPREF0693_3204 HMPREF0693_2800 HMPREF0693_1037 |
D | PROP (NRULE_0221) | Osmoprotectant transporter | HMPREF0693_0019 |
E | OPUE (NRULE_0222) | Sodium/proline symporter | HMPREF0693_1248 |
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) |
必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase | HMPREF0693_3212 |
PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase | HMPREF0693_1434 |
SERC (NRULE_0210) | Phosphoserine aminotransferase | HMPREF0693_2064 |
PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | HMPREF0693_2547 |
PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | HMPREF0693_1534 |