Alanine racemization(NFUNC_0063) |
必須 | A | ALR (NRULE_0228) | Alanine racemase | KPR_3220 KPR_0422 |
Ampicillin resistance(NFUNC_0046) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | KPR_2492 |
Anthranilate biosynthesis(NFUNC_0038) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | KPR_0724 KPR_2310 |
TRPE (NRULE_0143) | Anthranilate synthase component I | KPR_2311 |
Aromatic azo compounds degradation(NFUNC_0073) |
必須 | A | AZOR (NRULE_0236) | FMN-dependent NADH-azoreductase | KPR_1296 KPR_2860 |
Arsenical resistance(NFUNC_0004) |
必須 | A | ARSB1 (NRULE_0015) | Arsenical pump membrane protein | KPR_1724 |
ARSC1 (NRULE_0017) | Arsenate reductase | KPR_1887 KPR_1725 |
Bacitracin resistance(NFUNC_0022) |
必須 | A | UPPP (NRULE_0097) | Undecaprenyl-diphosphatase | KPR_4493 |
Beta-lactam antibiotic resistance(NFUNC_0033) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | KPR_2492 |
Betaine biosynthesis (from choline)(NFUNC_0049) |
必須 | A | BETA (NRULE_0175) | Choline dehydrogenase | KPR_3975 |
Chloramphenicol resistance(NFUNC_0025) |
必須 | A | CAT1 (NRULE_0107) | Chloramphenicol acetyltransferase | KPR_3058 |
Folate biosynthesis(NFUNC_0044) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | KPR_0724 KPR_2310 |
DHPS (NRULE_0144) | Dihydropteroate synthase | KPR_4780 |
FOLM (NRULE_0146) | Dihydrofolate reductase FolM | KPR_2820 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | KPR_4494 KPR_2013 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | KPR_1072 |
FOLC (NRULE_0160) | Bifunctional protein FolC | KPR_2001 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | KPR_3240 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | KPR_2134 |
B | GLAT (NRULE_0142) | Glutamine amidotransferase | KPR_0724 KPR_2310 |
DHPS (NRULE_0144) | Dihydropteroate synthase | KPR_4780 |
FOLA (NRULE_0147) | Dihydrofolate reductase | KPR_0969 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | KPR_4494 KPR_2013 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | KPR_1072 |
FOLC (NRULE_0160) | Bifunctional protein FolC | KPR_2001 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | KPR_3240 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | KPR_2134 |
Fosfomycin resistance(NFUNC_0023) |
必須 | A | FOSA (NRULE_0098) | Glutathione transferase FosA | KPR_0833 |
Macrolide antibiotic resistance(NFUNC_0045) |
必須 | B | RLMA (NRULE_0165) | 23S rRNA (guanine-N(1))-methyltransferase | KPR_3250 |
Metal-binding protein(NFUNC_0105) |
必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | KPR_3816 KPR_3820 |
B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | KPR_3820 |
C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | KPR_2673 KPR_1935 KPR_0349 KPR_3818 |
E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | KPR_4221 |
F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | KPR_0446 |
H | NIKR (NRULE_0331) | Nickel-responsive transcriptional regulator NikR | KPR_5062 |
I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | KPR_1412 |
Molybdate transport (ABC transporter)(NFUNC_0097) |
必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | KPR_0349 KPR_1935 KPR_2673 KPR_3818 |
任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | KPR_3820 |
| MODB (NRULE_0325) | Molybdate ABC transporter permease protein | KPR_3817 |
| MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | KPR_3816 |
(R)-pantothenate biosynthesis(NFUNC_0030) |
必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | KPR_1069 |
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | KPR_1071 |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | KPR_4343 |
PANC (NRULE_0118) | Pantothenate synthetase | KPR_1070 |
Penicillin resistance(NFUNC_0047) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | KPR_2492 |
Pyrroloquinoline quinone biosynthesis(NFUNC_0020) |
必須 | A | PQQC (NRULE_0092) | Pyrroloquinoline-quinone synthase | KPR_2418 |
任意 | | PQQB (NRULE_0091) | Coenzyme PQQ synthesis protein B | KPR_2419 |
| PQQD (NRULE_0093) | Coenzyme PQQ synthesis protein D | KPR_2417 |
| PQQE (NRULE_0094) | Coenzyme PQQ synthesis protein E | KPR_2416 |
| PQQF (NRULE_0095) | Coenzyme PQQ synthesis protein F | KPR_2415 |
Riboflavin biosynthesis(NFUNC_0058) |
必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | KPR_4486 |
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | KPR_2325 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | KPR_4355 |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | KPR_4354 |
RIBE (NRULE_0204) | Riboflavin synthase | KPR_3042 |
任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | KPR_0953 |
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031) |
必須 | A | TPS (NRULE_0119) | Trehalose-phosphate synthase | KPR_3305 |
TPP (NRULE_0120) | Trehalose-6-phosphate phosphatase | KPR_3306 |
Uptake of osmoprotectant(NFUNC_0061) |
必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | KPR_1279 |
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | KPR_1280 |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | KPR_1281 |
C | BCCT (NRULE_0220) | BCCT family transporter | pKPR_0129 KPR_3508 KPR_3972 |
D | PROP (NRULE_0221) | Osmoprotectant transporter | KPR_0484 |
E | OPUE (NRULE_0222) | Sodium/proline symporter | KPR_3481 |
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) |
必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase | KPR_4620 |
PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase | KPR_1996 |
SERC (NRULE_0210) | Phosphoserine aminotransferase | KPR_3643 |
PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | KPR_2164 KPR_2528 KPR_0973 |
PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | KPR_1384 |