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遺伝子 : Pyrroloquinoline-quinone synthase (PQQC)

遺伝子情報

ID NRULE_0092
遺伝子ID PQQC
作成日 2012/12/13
タンパク質名
Protein name
Full
Pyrroloquinoline-quinone synthase
EC
EC 1.3.3.11
Synonym
Full
Coenzyme PQQ synthesis protein C
Pyrroloquinoline quinone biosynthesis protein C
遺伝子名 pqqC
遺伝子条件 HAMAP; MF_00654; hit=1
参照
Gene Ontology
GO
GO:0033732, F:pyrroloquinoline-quinone synthase activity, IEA:EC
GO:0018189, P:pyrroloquinoline quinone biosynthetic process, IEA:UniProtKB-KW
Enzyme and pathway databases
UniPathway
UPA00539, -
Family and domain databases
HAMAP
MF_00654, PQQ_syn_PqqC, 1, -
InterPro
IPR016084, Haem_Oase-like_multi-hlx
IPR011845, PQQ_synth_PqqC
IPR004305, Thiaminase-2/PQQC
Pfam
PF03070, TENA_THI-4, 1
TIGRFAMs
TIGR02111, PQQ_syn_pqqC, 1
配列の特徴 該当データなし
注釈
Function
Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Catalytic activity
6-(2-amino-2-carboxyethyl)-7,8-dioxo- 1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5- dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O
Pathway
Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis
Subunit structure
Homodimer
Sequence similarities
Belongs to the PqqC family
参考文献
P27505 Klebsiella pneumoniae.
1313537
Nucleotide sequence and structure of the Klebsiella pneumoniae pqq operon. (Mol Gen Genet. 1992)
7665488
Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection of an intermediate in the biosynthetic pathway. (J Bacteriol. 1995)



関与する機能

機能名
Pyrroloquinoline quinone biosynthesis

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acetobacter aceti14818AaceN1_010100006258pyrroloquinoline quinone biosynthesis protein PqqC
Acetobacter pasteurianus105190APA32_21270Coenzyme Pyrrolo-quinoline quinone (PQQ) synthesis protein C PqqC
Acetobacter pasteurianus101655APT_1458coenzyme Pyrrolo-quinoline quinone synthesis protein C PqqC
Acetobacter tropicalis101654ATPR_3027coenzyme Pyrrolo-quinoline quinone (PQQ) synthesis protein C PqqC
Acidiphilium multivorum100883ACMV_01040coenzyme PQQ synthesis protein C
ACMV_03540coenzyme PQQ synthesis protein C
Actinoalloteichus cyanogriseus14455G443_01_04420pyrroloquinoline quinone biosynthesis protein PqqC
Actinoalloteichus spitiensis102582ACTIDRAF_06770hypothetical protein
Alteromonas macleodii102226MASE_15510pyrroloquinoline quinone biosynthesis protein PqqC
Amycolatopsis azurea14573C791_3107Coenzyme PQQ synthesis protein C
Amycolatopsis mediterranei13415RAM_40415pyrroloquinoline quinone biosynthesis protein PqqC
Bradyrhizobium diazoefficiens14792blr6737probable pyrroloquinoline quinone synthesis protein C
Chthoniobacter flavusCfE428DRAFT_2149coenzyme PQQ biosynthesis protein C
Chthonomonas calidiroseaCCALI_00348coenzyme PQQ biosynthesis protein C
Cystobacter fuscus100088D187_002724Coenzyme PQQ synthesis protein C
Enterobacter aerogenes13534EAE_19565pyrroloquinoline quinone biosynthesis protein PqqC
Enterobacter hormaechei105718HMPREF9086_0390coenzyme PQQ synthesis protein C (pyrroloquinoline quinone biosynthesis protein C)
Frateuria aurantia3245Fraau_0285coenzyme PQQ biosynthesis protein C
Geodermatophilus obscurus13315Gobs_2454coenzyme PQQ biosynthesis protein C
Gluconacetobacter hansenii14816GXY_00883pyrroloquinoline quinone biosynthesis protein PqqC
Gluconobacter frateurii101659GfraN1_010100006391pyrroloquinoline quinone biosynthesis protein PqqC
Klebsiella pneumoniae14438KPR_2418
Klebsiella pneumoniae subsp. rhinoscleromatis105682HMPREF0484_4541coenzyme PQQ biosynthesis protein C
Limnochorda pilosa110152LIP_1137pyrroloquinoline quinone biosynthesis protein PqqC
Magnetospirillum magnetotacticum15272Magn03005047COG5424: Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
Magn03006481COG5424: Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
Magn03007676COG5424: Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
Methylacidiphilum infernorumMinf_1235Coenzyme PQQ synthesis protein C
Methylobacterium radiotolerans15690Mrad2831_0517coenzyme PQQ biosynthesis protein C
Pseudomonas putida100650PP_0378coenzyme PQQ synthesis protein C
Pseudomonas stutzeri14165PSTAB_1968pyrroloquinoline quinone biosynthesis protein PqqC
Rahnella aquatilis105701Rahaq2_4823coenzyme PQQ biosynthesis protein C
Rhizobium sp.101917NGR_b03280pyrroloquinoline-quinone synthase
Rhodobacter sphaeroides12203RSP_0792probable pyrroloquinoline quinone synthesis protein C
Roseobacter denitrificans15277RD1_1152coenzyme PQQ biosynthesis protein C
Roseobacter litoralis15278RLO149_c036940coenzyme PQQ biosynthesis protein C
Saccharomonospora cyanea14841SaccyDRAFT_2356coenzyme PQQ biosynthesis protein C
Saccharomonospora glauca14831SacglDRAFT_02133coenzyme PQQ biosynthesis protein C
Saccharopolyspora erythraea13426SACE_4446coenzyme PQQ synthesis protein C
Saccharopolyspora spinosa15153SspiN1_010100007100pyrroloquinoline quinone biosynthesis protein PqqC
SspiN1_010100018521pyrroloquinoline quinone biosynthesis protein PqqC
Saccharothrix espanaensis15066BN6_07650Bifunctional coenzyme PQQ synthesis protein C/D
Serratia odorifera102598HMPREF0758_3730coenzyme PQQ biosynthesis protein C
Stackebrandtia nassauensis102104Snas_2177coenzyme PQQ biosynthesis protein C
Starkeya novella14993Snov_1055coenzyme PQQ biosynthesis protein C
Streptomyces clavuligerus13307SCLAV_5105pyrroloquinoline quinone biosynthesis protein PqqC
Thauera linaloolentis102519C666_10730pyrroloquinoline quinone biosynthesis protein PqqC