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Rule : Coenzyme PQQ synthesis protein E (PQQE)

Rule Description

Rule name PQQE
Created 2012-12-13
Protein name
Protein name
Coenzyme PQQ synthesis protein E
Pyrroloquinoline quinone biosynthesis protein E
Gene name pqqE
Rule Trigger HAMAP; MF_00660; hit=1
Cross Reference
Gene Ontology
GO:0051539, F:4 iron, 4 sulfur cluster binding, IEA:UniProtKB-KW
GO:0003824, F:catalytic activity, IEA:InterPro
GO:0046872, F:metal ion binding, IEA:UniProtKB-KW
GO:0018189, P:pyrroloquinoline quinone biosynthetic process, IEA:UniProtKB-KW
Enzyme and pathway databases
UPA00539, -
Family and domain databases
MF_00660, PqqE, 1, -
IPR023885, 4Fe4S-binding_SPASM_dom
IPR013785, Aldolase_TIM
IPR006638, Elp3/MiaB/NifB
IPR000385, MoaA_NifB_PqqE_Fe-S-bd_CS
IPR011843, PQQ_synth_PqqE_bac
IPR007197, rSAM
IPR017200, rSAM_PqqE/NirJ
PF13186, DUF4008, 1
PF04055, Radical_SAM, 1
PIRSF037420, PQQ_syn_pqqE, 1
SM00729, Elp3, 1
TIGR02109, PQQ_syn_pqqE, 1
P27507 Klebsiella pneumoniae.
METAL22Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity).
METAL26Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity).
METAL29Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity).
General annotation
Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity)
Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis
Sequence similarities
Belongs to the radical SAM superfamily. PqqE family
P27507 Klebsiella pneumoniae.
Nucleotide sequence and structure of the Klebsiella pneumoniae pqq operon. (Mol Gen Genet. 1992)
Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection of an intermediate in the biosynthetic pathway. (J Bacteriol. 1995)

Related Function

Function name
Pyrroloquinoline quinone biosynthesis


Data Download
Scientific name NBRC No. CDS Product name
Acetobacter aceti14818AaceN1_010100006248pyrroloquinoline quinone biosynthesis protein PqqE
Acetobacter pasteurianus105190APA32_21290Coenzyme Pyrrolo-quinoline quinone (PQQ) synthesis protein E PqqE
Acetobacter pasteurianus101655APT_1460coenzyme Pyrrolo-quinoline quinone synthesis protein E PqqE
Acetobacter tropicalis101654ATPR_3003coenzyme Pyrrolo-quinoline quinone (PQQ) synthesis protein E PqqE
Acidiphilium multivorum100883ACMV_01060coenzyme PQQ synthesis protein E
Actinoalloteichus cyanogriseus14455G443_01_04440pyrroloquinoline quinone biosynthesis protein PqqE
Actinoalloteichus spitiensis102582ACTIDRAF_06780hypothetical protein
Alteromonas macleodii102226MASE_15520pyrroloquinoline quinone biosynthesis protein PqqE
Amycolatopsis azurea14573C791_3109Coenzyme PQQ synthesis protein E
Amycolatopsis mediterranei13415RAM_40425pyrroloquinoline quinone biosynthesis protein PqqE
Bradyrhizobium diazoefficiens14792blr6739probable pyrroloquinoline quinone synthesis protein E
Chthoniobacter flavusCfE428DRAFT_2147coenzyme PQQ biosynthesis protein E
Chthonomonas calidiroseaCCALI_00346coenzyme PQQ biosynthesis enzyme PqqE
Cystobacter fuscus100088D187_002722Coenzyme PQQ synthesis protein E
Enterobacter aerogenes13534EAE_19575pyrroloquinoline quinone biosynthesis protein PqqE
Enterobacter hormaechei105718HMPREF9086_0392coenzyme PQQ synthesis protein E (pyrroloquinoline quinone biosynthesis protein E)
Frateuria aurantia3245Fraau_0287coenzyme PQQ biosynthesis protein E
Geodermatophilus obscurus13315Gobs_2456coenzyme PQQ biosynthesis protein E
Gluconacetobacter hansenii14816GXY_00893pyrroloquinoline quinone biosynthesis protein PqqE
Gluconobacter frateurii101659GfraN1_010100006401pyrroloquinoline quinone biosynthesis protein PqqE
Klebsiella pneumoniae14438KPR_2416
Klebsiella pneumoniae subsp. rhinoscleromatis105682HMPREF0484_4543coenzyme PQQ biosynthesis protein E
Limnochorda pilosa110152LIP_1139pyrroloquinoline quinone biosynthesis protein PqqE
Magnetospirillum magnetotacticum15272Magn03009729COG0535: Predicted Fe-S oxidoreductases
Methylacidiphilum infernorumMinf_1237Coenzyme PQQ synthesis protein E, radical SAM superfamily enzyme
Methylobacterium radiotolerans15690Mrad2831_0516coenzyme PQQ biosynthesis protein E
Pseudomonas putida100650PP_0376coenzyme PQQ synthesis protein E
Pseudomonas stutzeri14165PSTAB_1970pyrroloquinoline quinone biosynthesis protein PqqE
Rahnella aquatilis105701Rahaq2_4821coenzyme PQQ biosynthesis protein E
Rhizobium sp.101917NGR_b03300coenzyme PQQ synthesis protein E
Rhodobacter sphaeroides12203RSP_0790probable Coenzyme PQQ synthesis protein E
Roseobacter denitrificans15277RD1_1150coenzyme PQQ biosynthesis protein E
Roseobacter litoralis15278RLO149_c036960coenzyme PQQ biosynthesis protein E
Saccharomonospora cyanea14841SaccyDRAFT_2354coenzyme PQQ biosynthesis protein E
Saccharomonospora glauca14831SacglDRAFT_02131coenzyme PQQ biosynthesis protein E
Saccharopolyspora erythraea13426SACE_4425coenzyme PQQ synthesis protein E
Saccharopolyspora spinosa15153SspiN1_010100007105pyrroloquinoline quinone biosynthesis protein PqqE
SspiN1_010100018531pyrroloquinoline quinone biosynthesis protein PqqE
Saccharothrix espanaensis15066BN6_07630Coenzyme PQQ synthesis protein E
Serratia odorifera102598HMPREF0758_3728coenzyme PQQ biosynthesis protein E
Stackebrandtia nassauensis102104Snas_2175coenzyme PQQ biosynthesis protein E
Starkeya novella14993Snov_1057coenzyme PQQ biosynthesis protein E
Streptomyces clavuligerus13307SCLAV_5107pyrroloquinoline quinone biosynthesis protein PqqE
Thauera linaloolentis102519C666_10720pyrroloquinoline quinone biosynthesis protein PqqE