| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q3S868_9ACTO (Q3S868) |
|
|
0.0 |
4005 |
100% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
2
|
C9YYI4_STRSW (C9YYI4) |
|
|
0.0 |
3446 |
92% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83931
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
4
|
E2Q517_STRCL (E2Q517) |
|
|
0.0 |
2143 |
61% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0011
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
5
|
E4NJF5_KITSK (E4NJF5) |
|
|
0.0 |
2031 |
61% |
|
- Product
- Modular polyketide synthase BFAS5
- Gene
- bfmA5
KSE_73480
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
7
|
E0D206_9ACTO (E0D206) |
|
(2 hsp) |
0.0 |
1790 |
53% |
|
- Product
- Polyketide synthase
- Gene
- gfsE
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
9
|
Q52V49_9ACTO (Q52V49) |
|
(2 hsp) |
0.0 |
1699 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
10
|
B1W4J5_STRGG (B1W4J5) |
|
(3 hsp) |
0.0 |
1696 |
50% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-5
SGR_6183
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
11
|
Q3S863_9ACTO (Q3S863) |
|
(3 hsp) |
0.0 |
1677 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
12
|
A1YAN1_AMYOR (A1YAN1) |
|
|
0.0 |
1666 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
14
|
C9YYI2_STRSW (C9YYI2) |
|
(3 hsp) |
0.0 |
1652 |
55% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
16
|
Q70KH8_9ACTO (Q70KH8) |
|
(2 hsp) |
0.0 |
1640 |
53% |
|
- Product
- Polyketide synthase type I
- Gene
- aurA
- Organism
- Streptomyces thioluteus
|
1uniprot[Pubmed] 14700630 Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster.(Chem. Biol.) [2003] |
|
18
|
D7CFC9_STRBB (D7CFC9) |
|
(3 hsp) |
0.0 |
1639 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SBI_01544
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
19
|
Q76KZ3_STRHA (Q76KZ3) |
|
(3 hsp) |
0.0 |
1638 |
50% |
|
- Product
- Polyketide synthase modules 7-8
- Gene
- vinP4
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
21
|
D7AWH7_NOCDD (D7AWH7) |
|
|
0.0 |
1635 |
50% |
|
- Product
- Acyl transferase
- Gene
- Ndas_0496
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
22
|
B6ZK69_STRLS (B6ZK69) |
|
|
0.0 |
1630 |
53% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd16
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
23
|
E2Q519_STRCL (E2Q519) |
|
(3 hsp) |
0.0 |
1628 |
56% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0013
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
24
|
C9YYI3_STRSW (C9YYI3) |
|
(5 hsp) |
0.0 |
1626 |
56% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
27
|
Q0R4M3_STRAT (Q0R4M3) |
|
(3 hsp) |
0.0 |
1618 |
54% |
|
- Product
- ChlA5
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
28
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(3 hsp) |
0.0 |
1617 |
49% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
31
|
F1DI31_9ACTO (F1DI31) |
|
(7 hsp) |
0.0 |
1605 |
55% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
33
|
A4FH85_SACEN (A4FH85) |
|
(5 hsp) |
0.0 |
1600 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
34
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(5 hsp) |
0.0 |
1600 |
54% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
35
|
Q3S869_9ACTO (Q3S869) |
|
(5 hsp) |
0.0 |
1598 |
56% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
36
|
A0FCL2_STRVO (A0FCL2) |
|
(6 hsp) |
0.0 |
1598 |
54% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
37
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(7 hsp) |
0.0 |
1595 |
55% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
38
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(6 hsp) |
0.0 |
1592 |
53% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
39
|
E4NJF3_KITSK (E4NJF3) |
|
(3 hsp) |
0.0 |
1582 |
55% |
|
- Product
- Modular polyketide synthase BFAS3
- Gene
- bfmA3
KSE_73460
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
42
|
Q68BG4_STRHA (Q68BG4) |
|
(7 hsp) |
0.0 |
1577 |
52% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
46
|
D6C473_9ACTO (D6C473) |
|
(7 hsp) |
0.0 |
1573 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA2
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
48
|
Q82QT5_STRAW (Q82QT5) |
|
(2 hsp) |
0.0 |
1565 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
SAV418 SAV_418
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
49
|
F8QPF9_9ACTO (F8QPF9) |
|
(3 hsp) |
0.0 |
1563 |
52% |
|
- Product
- Polyketide synthase
- Gene
- natB
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
50
|
Q84G23_STRHY (Q84G23) |
|
(3 hsp) |
0.0 |
1563 |
51% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
51
|
C3VLZ6_9ACTO (C3VLZ6) |
|
|
0.0 |
1563 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaG
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
52
|
Q93H86_STRAW (Q93H86) |
|
(2 hsp) |
0.0 |
1563 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
53
|
B6ZIR3_STRPT (B6ZIR3) |
|
(5 hsp) |
0.0 |
1562 |
53% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
55
|
Q1L0T1_STRHY (Q1L0T1) |
|
(3 hsp) |
0.0 |
1559 |
51% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
56
|
Q93HJ1_STRAW (Q93HJ1) |
|
(3 hsp) |
0.0 |
1558 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA7
SAV2895 SAV_2895
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
57
|
D7C428_STRBB (D7C428) |
|
(7 hsp) |
0.0 |
1557 |
46% |
|
- Product
- Modular polyketide synthase
- Gene
- milA4
SBI_00729
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
58
|
Q6JHN8_9PSEU (Q6JHN8) |
|
(5 hsp) |
0.0 |
1555 |
53% |
|
- Product
- ObsA
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
60
|
D7P611_CHOCO (D7P611) |
|
(5 hsp) |
0.0 |
1552 |
53% |
|
- Product
- TugA
- Gene
- tugA
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
61
|
D6C474_9ACTO (D6C474) |
|
(5 hsp) |
0.0 |
1549 |
46% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA4
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
62
|
E0D205_9ACTO (E0D205) |
|
(2 hsp) |
0.0 |
1548 |
52% |
|
- Product
- Polyketide synthase
- Gene
- gfsD
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
63
|
E4NJF4_KITSK (E4NJF4) |
|
(3 hsp) |
0.0 |
1546 |
55% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
65
|
D6C477_9ACTO (D6C477) |
|
(4 hsp) |
0.0 |
1545 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA3
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
66
|
Q49BE0_STRHY (Q49BE0) |
|
(3 hsp) |
0.0 |
1545 |
51% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
69
|
Q6JHN6_9PSEU (Q6JHN6) |
|
(5 hsp) |
0.0 |
1540 |
54% |
|
- Product
- ObsC
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
72
|
E2Q518_STRCL (E2Q518) |
|
(3 hsp) |
0.0 |
1536 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0012
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
73
|
A1YAM8_AMYOR (A1YAM8) |
|
|
0.0 |
1535 |
54% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
74
|
C6WNW1_ACTMD (C6WNW1) |
|
(5 hsp) |
0.0 |
1535 |
53% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2695
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
75
|
Q84G22_STRHY (Q84G22) |
|
(3 hsp) |
0.0 |
1534 |
51% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
76
|
B2HNF4_MYCMM (B2HNF4) |
|
|
0.0 |
1531 |
52% |
|
- Product
- Type I modular polyketide synthase
- Gene
- MMAR_3797
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
78
|
Q1L0T0_STRHY (Q1L0T0) |
|
(3 hsp) |
0.0 |
1530 |
51% |
|
- Product
- GelC
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
80
|
Q93HI9_STRAW (Q93HI9) |
|
|
0.0 |
1528 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA5
SAV2893 SAV_2893
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
81
|
Q0R4M8_STRAT (Q0R4M8) |
|
(4 hsp) |
0.0 |
1526 |
52% |
|
- Product
- ChlA1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
82
|
F1CT52_9ACTO (F1CT52) |
|
(3 hsp) |
0.0 |
1524 |
51% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
83
|
C3VLW9_9ACTO (C3VLW9) |
|
(2 hsp) |
0.0 |
1524 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- becF
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
84
|
C3VLZ7_9ACTO (C3VLZ7) |
|
(2 hsp) |
0.0 |
1523 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaF
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
87
|
O30482_STRHY (O30482) |
|
|
0.0 |
1521 |
47% |
|
- Product
- PKS module 4
- Gene
-
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 9426000 [Medline] 98085969 A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain.(Gene) [1997] |
|
91
|
D1GLV9_9ACTO (D1GLV9) |
|
(6 hsp) |
0.0 |
1517 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
92
|
D7CDZ7_STRBB (D7CDZ7) |
|
(2 hsp) |
0.0 |
1516 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SBI_01541
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
93
|
C3VLV8_9ACTO (C3VLV8) |
|
(2 hsp) |
0.0 |
1516 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- becB
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
95
|
F1DI32_9ACTO (F1DI32) |
|
(3 hsp) |
0.0 |
1516 |
51% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
98
|
F1CT53_9ACTO (F1CT53) |
|
(3 hsp) |
0.0 |
1514 |
51% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
100
|
Q06BM4_STRHY (Q06BM4) |
|
(3 hsp) |
0.0 |
1513 |
51% |
|
- Product
- GdmPKS
- Gene
- gdmPKS
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 18214443 The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.(Arch. Microbiol.) [2008] |
|