| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q9L8C6_SORCE (Q9L8C6) |
|
|
0.0 |
7490 |
100% |
|
- Product
- Polyketide synthase
- Gene
- epoD
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 10662695 [Medline] 20130945 The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90.(Chem. Biol.) [2000] |
|
2
|
Q9KIZ6_SORCE (Q9KIZ6) |
|
|
0.0 |
7380 |
98% |
|
- Product
- EpoE
- Gene
- epoE
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 10649995 [Medline] 20115953 Cloning and heterologous expression of the epothilone gene cluster.(Science) [2000] | 2uniprot[Pubmed] 10831849 [Medline] 20293058 Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum.(Gene) [2000] | [pubmed all]
|
5
|
Q9KIZ7_SORCE (Q9KIZ7) |
|
(15 hsp) |
0.0 |
2790 |
65% |
|
- Product
- EpoD
- Gene
- epoD
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 10649995 [Medline] 20115953 Cloning and heterologous expression of the epothilone gene cluster.(Science) [2000] | 2uniprot[Pubmed] 10831849 [Medline] 20293058 Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum.(Gene) [2000] | [pubmed all]
|
6
|
Q9L8C7_SORCE (Q9L8C7) |
|
(15 hsp) |
0.0 |
2771 |
65% |
|
- Product
- Polyketide synthase
- Gene
- epoC
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 10662695 [Medline] 20130945 The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90.(Chem. Biol.) [2000] |
|
9
|
Q93TW9_STIAU (Q93TW9) |
|
(9 hsp) |
0.0 |
2052 |
46% |
|
- Product
- MxaC
- Gene
- mxaC
- Organism
- Stigmatella aurantiaca
|
1uniprot[Pubmed] 11182319 [Medline] 21110452 Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15.(Chem. Biol.) [2001] |
|
10
|
Q1D3S8_MYXXD (Q1D3S8) |
|
(9 hsp) |
0.0 |
1996 |
46% |
|
- Product
- Polyketide synthase
- Gene
- MXAN_4527
- Organism
- Myxococcus xanthus (strain DK 1622)
|
1uniprot[Pubmed] 17015832 Evolution of sensory complexity recorded in a myxobacterial genome.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
11
|
Q3LRL4_9DELT (Q3LRL4) |
|
(5 hsp) |
0.0 |
1950 |
47% |
|
- Product
- MmxC
- Gene
- mmxC
- Organism
- Cystobacter fuscus
|
1uniprot[Pubmed] 16556988 Biosynthesis of 2'-O-methylmyxalamide D in the myxobacterium Cystobacter fuscus: a polyketide synthase-nonribosomal peptide synthetase system for the myxalamide D skeleton and a methyltransferase for the final O-methylation.(Biosci. Biotechnol. Biochem.) [2006] |
|
13
|
Q53840_SORCE (Q53840) |
|
(10 hsp) |
0.0 |
1857 |
45% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
14
|
A4D934_9NOSO (A4D934) |
|
(4 hsp) |
0.0 |
1846 |
39% |
|
- Product
- CrpB
- Gene
- crpB
- Organism
- Nostoc sp. ATCC 53789
|
1uniprot[Pubmed] 17240975 Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.(ACS Chem. Biol.) [2006] |
|
16
|
A4F5D7_SORCE (A4F5D7) |
|
(4 hsp) |
0.0 |
1776 |
45% |
|
- Product
- Polyketide synthase
- Gene
- spiE
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
17
|
A4F5C6_SORCE (A4F5C6) |
|
(6 hsp) |
0.0 |
1761 |
44% |
|
- Product
- Polyketide synthase
- Gene
- spiG
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
18
|
A1YBT8_SORCE (A1YBT8) |
|
(4 hsp) |
0.0 |
1721 |
45% |
|
- Product
- JerE
- Gene
- jerE
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17185223 Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.(Chem. Biol.) [2006] |
|
19
|
Q7WTD6_9ACTO (Q7WTD6) |
|
(4 hsp) |
0.0 |
1721 |
42% |
|
- Product
- NanA8
- Gene
- nanA8
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
21
|
D7BSM1_STRBB (D7BSM1) |
|
(4 hsp) |
0.0 |
1712 |
42% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
23
|
D7P614_CHOCO (D7P614) |
|
(8 hsp) |
0.0 |
1693 |
45% |
|
- Product
- TugD
- Gene
- tugD
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
24
|
A4F5C7_SORCE (A4F5C7) |
|
(8 hsp) |
0.0 |
1691 |
45% |
|
- Product
- Polyketide synthase
- Gene
- spiH
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
26
|
C9YYI3_STRSW (C9YYI3) |
|
(6 hsp) |
0.0 |
1684 |
41% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
28
|
Q93HJ1_STRAW (Q93HJ1) |
|
(4 hsp) |
0.0 |
1681 |
42% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA7
SAV2895 SAV_2895
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
29
|
E0D202_9ACTO (E0D202) |
|
(11 hsp) |
0.0 |
1676 |
45% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
30
|
Q3S869_9ACTO (Q3S869) |
|
(6 hsp) |
0.0 |
1667 |
41% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
31
|
Q846W6_STRCM (Q846W6) |
|
(4 hsp) |
0.0 |
1660 |
42% |
|
- Product
- Monensin polyketide synthase modules 11 and 12
- Gene
- monAVIII
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
32
|
F1DI32_9ACTO (F1DI32) |
|
(4 hsp) |
0.0 |
1659 |
41% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
33
|
A1YBQ3_SORCE (A1YBQ3) |
|
(4 hsp) |
0.0 |
1658 |
43% |
|
- Product
- AmbB
- Gene
- ambB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17185223 Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.(Chem. Biol.) [2006] |
|
34
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(9 hsp) |
0.0 |
1657 |
42% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
36
|
Q93HJ2_STRAW (Q93HJ2) |
|
(8 hsp) |
0.0 |
1651 |
44% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA6
SAV2896 SAV_2896
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
37
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(4 hsp) |
0.0 |
1650 |
41% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
38
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(9 hsp) |
0.0 |
1650 |
41% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
39
|
F1DI31_9ACTO (F1DI31) |
|
(9 hsp) |
0.0 |
1649 |
41% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
41
|
D1GLV8_9ACTO (D1GLV8) |
|
(4 hsp) |
0.0 |
1648 |
41% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
42
|
A0FCL1_STRVO (A0FCL1) |
|
(9 hsp) |
0.0 |
1647 |
42% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
43
|
E9LIP5_9ACTO (E9LIP5) |
|
(4 hsp) |
0.0 |
1645 |
42% |
|
- Product
- Putative modular polyketide synthase
- Gene
- tiaA2
- Organism
- Dactylosporangium aurantiacum subsp. hamdenensis
|
1uniprot[Pubmed] 21186805 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011] |
|
44
|
Q5SFB4_STRBI (Q5SFB4) |
|
(7 hsp) |
0.0 |
1642 |
43% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGI
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
46
|
Q6W5P9_9ACTO (Q6W5P9) |
|
(7 hsp) |
0.0 |
1639 |
41% |
|
- Product
- FscB
- Gene
- fscB
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
47
|
Q9KIV3_STRAT (Q9KIV3) |
|
(4 hsp) |
0.0 |
1638 |
41% |
|
- Product
- 8,8a-deoxyoleandolide synthase 2
- Gene
- oleAII
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
48
|
A4F7P0_SACEN (A4F7P0) |
|
(4 hsp) |
0.0 |
1637 |
42% |
|
- Product
- EryAII Erythromycin polyketide synthase modules 3 and 4
- Gene
- eryAII
SACE_0723
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] | 2uniprot[Pubmed] 17719492 Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.(Chem. Biol.) [2007] | [pubmed all]
|
49
|
Q5UNP5_SACER (Q5UNP5) |
|
(4 hsp) |
0.0 |
1637 |
42% |
|
- Product
- EryAII
- Gene
- eryAII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
50
|
Q52V51_9ACTO (Q52V51) |
|
(4 hsp) |
0.0 |
1636 |
43% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
52
|
B1W487_STRGG (B1W487) |
|
(4 hsp) |
0.0 |
1634 |
43% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-3
SGR_6075
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
53
|
B6ZIR3_STRPT (B6ZIR3) |
|
(11 hsp) |
0.0 |
1632 |
40% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
54
|
Q68BG4_STRHA (Q68BG4) |
|
(10 hsp) |
0.0 |
1630 |
41% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
55
|
C5HV14_STRAT (C5HV14) |
|
(8 hsp) |
0.0 |
1627 |
42% |
|
- Product
- Polyketide synthase
- Gene
- idmL
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
56
|
ERYA2_SACER (Q03132) |
|
(4 hsp) |
0.0 |
1626 |
42% |
|
- Product
- Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II DEBS 2 ORF 2
- Gene
- eryA
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 2024119 [Medline] 91220065 Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991] | 2uniprot[Pubmed] 1740151 [Medline] 92155230 6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992] | 3uniprot[Pubmed] 1618327 Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992] | 4uniprot[Pubmed] 12954331 The structure of docking domains in modular polyketide synthases.(Chem. Biol.) [2003] | [pubmed all]
|
57
|
Q9F829_9ACTO (Q9F829) |
|
(4 hsp) |
0.0 |
1625 |
41% |
|
- Product
- Megalomicin 6-deoxyerythronolide B synthase 2
- Gene
- megAII
- Organism
- Micromonospora megalomicea subsp. nigra
|
1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000] |
|
59
|
Q8KPW5_9ACTO (Q8KPW5) |
|
(7 hsp) |
0.0 |
1623 |
43% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSI
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
61
|
Q68BG5_STRHA (Q68BG5) |
|
(7 hsp) |
0.0 |
1618 |
43% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
67
|
E4NJF2_KITSK (E4NJF2) |
|
(8 hsp) |
0.0 |
1613 |
44% |
|
- Product
- Modular polyketide synthase BFAS2
- Gene
- bfmA2
KSE_73450
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
70
|
E2Q518_STRCL (E2Q518) |
|
(4 hsp) |
0.0 |
1605 |
40% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0012
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
71
|
C6ZCS1_9ACTO (C6ZCS1) |
|
(16 hsp) |
0.0 |
1604 |
42% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnA
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
73
|
E4NJF4_KITSK (E4NJF4) |
|
(4 hsp) |
0.0 |
1600 |
41% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
75
|
A4KCE4_9ACTO (A4KCE4) |
|
(16 hsp) |
0.0 |
1599 |
42% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] |
|
78
|
Q68BG3_STRHA (Q68BG3) |
|
(4 hsp) |
0.0 |
1598 |
40% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsC
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
80
|
D1GLV9_9ACTO (D1GLV9) |
|
(9 hsp) |
0.0 |
1597 |
41% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
81
|
Q8GBX5_SORCE (Q8GBX5) |
|
(4 hsp) |
0.0 |
1593 |
42% |
|
- Product
- Polyketide synthase
- Gene
- spiI
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
84
|
Q3S864_9ACTO (Q3S864) |
|
(7 hsp) |
0.0 |
1589 |
44% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
87
|
A0ACI3_STRAM (A0ACI3) |
|
(8 hsp) |
0.0 |
1586 |
41% |
|
- Product
- Putative type I modular polyketide synthase
- Gene
- SAMR0477
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
88
|
B1W4J5_STRGG (B1W4J5) |
|
(4 hsp) |
0.0 |
1585 |
41% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-5
SGR_6183
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
89
|
A4F7P1_SACEN (A4F7P1) |
|
(4 hsp) |
0.0 |
1583 |
44% |
|
- Product
- EryAIII Erythromycin polyketide synthase modules 5 and 6
- Gene
- eryAIII
SACE_0724
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
90
|
Q5UNP4_SACER (Q5UNP4) |
|
(4 hsp) |
0.0 |
1583 |
44% |
|
- Product
- EryAIII
- Gene
- eryAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] | 2uniprot[Pubmed] 16844787 The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.(Proc. Natl. Acad. Sci. U.S.A.) [2006] | [pubmed all]
|
92
|
C0SMW4_9ACTO (C0SMW4) |
|
(18 hsp) |
0.0 |
1582 |
42% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
93
|
B6ZIR2_STRPT (B6ZIR2) |
|
(11 hsp) |
0.0 |
1580 |
42% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
95
|
Q93H87_STRAW (Q93H87) |
|
(10 hsp) |
0.0 |
1576 |
40% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
96
|
Q9L4W4_9ACTO (Q9L4W4) |
|
(5 hsp) |
0.0 |
1575 |
43% |
|
- Product
- NysB
- Gene
- nysB
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
97
|
Q82QT4_STRAW (Q82QT4) |
|
(13 hsp) |
0.0 |
1574 |
40% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
99
|
A8L4A9_FRASN (A8L4A9) |
|
(6 hsp) |
0.0 |
1574 |
41% |
|
- Product
- Erythronolide synthase
- Gene
- Franean1_3887
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
100
|
C9YYI1_STRSW (C9YYI1) |
|
(7 hsp) |
0.0 |
1573 |
44% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|