BLAST table : Megalo_00130

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q9F829_9ACTO
(Q9F829)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3562 (3562)
 0.0 6928   100% Megalomicin 6-deoxyerythronolide B synthase 2 megAII Micromonospora megalomicea subsp. nigra
2
 A4F7P0_SACEN
(A4F7P0)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5086   76% EryAII Erythromycin polyketide synthase modules 3 and 4 eryAII
SACE_0723		 Saccharopolyspora erythraea (strain NRRL 23338)
3
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5086   76% EryAII eryAII Saccharopolyspora erythraea
Streptomyces erythraeus
4
 ERYA2_SACER
(Q03132)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5064   76% Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II
DEBS 2
ORF 2		 eryA Saccharopolyspora erythraea
Streptomyces erythraeus		 2.3.1.94
5
 Q83X70_STRRO
(Q83X70)		 
[query] 1 - 3561 (3562)
[subject] 1 - 3654 (3656)
 0.0 3640   59% Lankamycin synthase LkmAII lkmAII Streptomyces rochei
Streptomyces parvullus
6
 Q5Y9G5_9ACTO
(Q5Y9G5)		 
[query] 4 - 3561 (3562)
[subject] 7 - 3571 (3574)
 0.0 3287   56% Polyketide synthase modules 3 and 4 eryAII Aeromicrobium erythreum
7
 E0KRC7_STRVO
(E0KRC7)		 
[query] 31 - 3486 (3562)
[subject] 191 - 3757 (5559)
(8 hsp)		 0.0 2863   50% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
8
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 31 - 3483 (3562)
[subject] 1734 - 5374 (7178)
(11 hsp)		 0.0 2833   49% MerB merB Streptomyces violaceoniger
9
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 31 - 3483 (3562)
[subject] 1729 - 5298 (7102)
(11 hsp)		 0.0 2821   50% Polyketide synthase merB Streptomyces sp. NRRL 30748
10
 B4VEL0_9ACTO
(B4VEL0)		 
[query] 2 - 3557 (3562)
[subject] 13 - 3759 (3761)
 0.0 2760   48% Polyketide synthase subunit SSAG_06220 Streptomyces sp. Mg1
11
 O33956_STRFR
(O33956)		 
[query] 4 - 3556 (3562)
[subject] 13 - 3729 (3729)
 0.0 2754   48% Tylactone synthase modules 4 & 5 tylG Streptomyces fradiae
Streptomyces roseoflavus
12
 E0KBI4_STRVO
(E0KBI4)		 
[query] 31 - 3557 (3562)
[subject] 4507 - 8273 (8275)
(8 hsp)		 0.0 2743   46% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
13
 A9YLB4_9ACTO
(A9YLB4)		 
[query] 2 - 3556 (3562)
[subject] 14 - 3850 (3850)
 0.0 2741   47% AngAIII angAIII Streptomyces eurythermus
14
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 17 - 3557 (3562)
[subject] 3 - 3732 (3734)
 0.0 2732   48% Putative type I polyketide synthase gerSIII Streptomyces sp. KCTC 0041BP
15
 E0KRC6_STRVO
(E0KRC6)		 
[query] 28 - 3482 (3562)
[subject] 5917 - 9411 (11118)
(14 hsp)		 0.0 2697   48% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
16
 Q9ZGI4_9ACTO
(Q9ZGI4)		 Jump to Pikro_00040 
[query] 3 - 3557 (3562)
[subject] 5 - 3735 (3739)
 0.0 2676   48% Type I polyketide synthase PikAII pikAII Streptomyces venezuelae
17
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 28 - 3482 (3562)
[subject] 5941 - 9538 (11604)
(17 hsp)		 0.0 2662   47% MerC merC Streptomyces violaceoniger
18
 A0ACH1_STRAM
(A0ACH1)		 
[query] 2 - 3482 (3562)
[subject] 3 - 3570 (8154)
(9 hsp)		 0.0 2613   48% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
19
 Q0ILD4_9ACTO
(Q0ILD4)		 
[query] 29 - 3471 (3562)
[subject] 2477 - 6054 (6148)
(7 hsp)		 0.0 2474   47% NlmA1 nlmA1 Streptomyces nanchangensis
20
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 30 - 3478 (3562)
[subject] 2077 - 5632 (5710)
(5 hsp)		 0.0 2444   46% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
21
 D7C2B8_STRBB
(D7C2B8)		 
[query] 2 - 3483 (3562)
[subject] 3 - 3621 (7498)
(5 hsp)		 0.0 2444   46% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
22
 B1W4J4_STRGG
(B1W4J4)		 
[query] 1 - 3557 (3562)
[subject] 7 - 3721 (3723)
 0.0 2443   45% Putative type-I PKS pks2-4
SGR_6182		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
23
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 29 - 3557 (3562)
[subject] 2465 - 6143 (6146)
(7 hsp)		 0.0 2430   46% Modular polyketide synthase olmA1
SAV2899
SAV_2899		 Streptomyces avermitilis
24
 B1W489_STRGG
(B1W489)		 
[query] 9 - 3482 (3562)
[subject] 18 - 3654 (3734)
 0.0 2429   46% Putative type-I PKS pks1-5
SGR_6077		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
25
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 7 - 3562 (3562)
[subject] 4088 - 7771 (7771)
(6 hsp)		 0.0 2368   44% FscE fscE Streptomyces sp. FR-008
26
 B1W4J2_STRGG
(B1W4J2)		 
[query] 31 - 3484 (3562)
[subject] 1580 - 5252 (5343)
(4 hsp)		 0.0 2363   45% Putative type-I PKS pks2-2
SGR_6180		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
27
 A0ACI2_STRAM
(A0ACI2)		 
[query] 4 - 3556 (3562)
[subject] 6 - 3562 (3565)
 0.0 2338   46% Putative modular polyketide synthase SAMR0476 Streptomyces ambofaciens ATCC 23877
28
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 1 - 2656 (3562)
[subject] 1 - 2790 (3816)
(4 hsp)		 0.0 2315   51% 8,8a-deoxyoleandolide synthase 2 oleAII Streptomyces antibioticus
29
 Q83WE8_MICGR
(Q83WE8)		 
[query] 1 - 3556 (3562)
[subject] 1 - 3646 (3649)
 0.0 2312   45% Protomycinolide IV synthase 3 mycAIII Micromonospora griseorubida
30
 C9YYI3_STRSW
(C9YYI3)		 
[query] 31 - 2801 (3562)
[subject] 1624 - 4544 (5001)
(7 hsp)		 0.0 2278   49% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
31
 D5ZU03_9ACTO
(D5ZU03)		 
[query] 31 - 2800 (3562)
[subject] 1474 - 4203 (4652)
(8 hsp)		 0.0 2250   51% Type I modular polyketide synthase SSFG_00092 Streptomyces ghanaensis ATCC 14672
32
 D7BSM1_STRBB
(D7BSM1)		 
[query] 3 - 2800 (3562)
[subject] 4 - 2975 (3439)
(4 hsp)		 0.0 2247   48% Type I polyketide synthase nanA8
SBI_08400		 Streptomyces bingchenggensis (strain BCW-1)
33
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 3 - 2800 (3562)
[subject] 17 - 2991 (3455)
(4 hsp)		 0.0 2246   48% NanA8 nanA8 Streptomyces nanchangensis
34
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 31 - 2801 (3562)
[subject] 1625 - 4547 (5006)
(7 hsp)		 0.0 2245   49% Modular polyketide synthase Streptomyces neyagawaensis
35
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 31 - 2800 (3562)
[subject] 1067 - 3812 (5721)
(10 hsp)		 0.0 2241   50% MerA merA Streptomyces violaceoniger
36
 F1DI32_9ACTO
(F1DI32)		 
[query] 1 - 2825 (3562)
[subject] 14 - 2983 (3378)
(4 hsp)		 0.0 2233   46% TrdAII Streptomyces sp. SCSIO1666
37
 E0KN03_STRVO
(E0KN03)		 
[query] 31 - 2773 (3562)
[subject] 1018 - 3731 (3735)
(6 hsp)		 0.0 2232   50% 6-deoxyerythronolide-B synthase., Mycocerosate synthase StrviDRAFT_3962 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
38
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 31 - 2800 (3562)
[subject] 1061 - 3805 (5712)
(10 hsp)		 0.0 2230   50% Polyketide synthase merA Streptomyces sp. NRRL 30748
39
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 1 - 2825 (3562)
[subject] 1 - 2970 (3365)
(4 hsp)		 0.0 2212   46% TamAII Streptomyces sp. 307-9
40
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 1 - 2773 (3562)
[subject] 19 - 3013 (3479)
(4 hsp)		 0.0 2199   47% Polyketide synthase type I slgA2 Streptomyces lydicus
41
 E0KBI6_STRVO
(E0KBI6)		 
[query] 31 - 2800 (3562)
[subject] 1601 - 4546 (4996)
(8 hsp)		 0.0 2192   46% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
42
 B1W4J5_STRGG
(B1W4J5)		 
[query] 1 - 2811 (3562)
[subject] 1 - 2919 (3579)
(4 hsp)		 0.0 2167   48% Putative type-I PKS pks2-5
SGR_6183		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
43
 Q5SFB2_STRBI
(Q5SFB2)		 Jump to Chalc_00230 
[query] 2 - 2661 (3562)
[subject] 8 - 2770 (3788)
(4 hsp)		 0.0 2153   49% Polyketide synthase subunit chmGIII Streptomyces bikiniensis
44
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 31 - 2806 (3562)
[subject] 1063 - 3957 (4441)
(8 hsp)		 0.0 2145   48% Polyketide synthase subunit chmGI Streptomyces bikiniensis
45
 E4NJF4_KITSK
(E4NJF4)		 
[query] 9 - 2801 (3562)
[subject] 3 - 2965 (3436)
(4 hsp)		 0.0 2121   47% Modular polyketide synthase BFAS4 bfmA4
KSE_73470		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
46
 F1DI31_9ACTO
(F1DI31)		 
[query] 29 - 2800 (3562)
[subject] 2531 - 5366 (5829)
(10 hsp)		 0.0 2120   47% TrdAI Streptomyces sp. SCSIO1666
47
 A8L4B1_FRASN
(A8L4B1)		 
[query] 1 - 2626 (3562)
[subject] 1 - 2853 (3493)
(4 hsp)		 0.0 2116   48% Beta-ketoacyl synthase Franean1_3889 Frankia sp. (strain EAN1pec)
48
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 31 - 2806 (3562)
[subject] 1008 - 3900 (4387)
(8 hsp)		 0.0 2115   47% Putative type I polyketide synthase gerSI Streptomyces sp. KCTC 0041BP
49
 F1ADM1_9ACTO
(F1ADM1)		 
[query] 4 - 2801 (3562)
[subject] 29 - 3040 (3511)
(4 hsp)		 0.0 2114   47% BafAIV Streptomyces lohii
50
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 29 - 2800 (3562)
[subject] 2531 - 5365 (5828)
(10 hsp)		 0.0 2114   47% TamAI Streptomyces sp. 307-9
51
 E2Q518_STRCL
(E2Q518)		 
[query] 3 - 2812 (3562)
[subject] 16 - 3121 (3596)
(4 hsp)		 0.0 2100   46% Modular polyketide synthase SCLAV_0012 Streptomyces clavuligerus ATCC 27064
52
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1 - 2800 (3562)
[subject] 1 - 2959 (7111)
(10 hsp)		 0.0 2092   46% Type I polyketide synthase hlsB Streptomyces halstedii
53
 A9YLB2_9ACTO
(A9YLB2)		 
[query] 14 - 2801 (3562)
[subject] 1054 - 3917 (4436)
(8 hsp)		 0.0 2080   48% AngAI angAI Streptomyces eurythermus
54
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 26 - 2825 (3562)
[subject] 3657 - 6632 (7026)
(11 hsp)		 0.0 2078   45% Polyketide synthase pldAII Streptomyces platensis
55
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 1 - 2828 (3562)
[subject] 1 - 2954 (3613)
(4 hsp)		 0.0 2076   46% Modular polyketide synthase olmA7
SAV2895
SAV_2895		 Streptomyces avermitilis
56
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 25 - 2808 (3562)
[subject] 1583 - 4572 (5277)
(6 hsp)		 0.0 2063   45% Modular polyketide synthase meiA4 Streptomyces nanchangensis
57
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 1 - 2828 (3562)
[subject] 1 - 2854 (3264)
(4 hsp)		 0.0 2060   46% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
58
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 31 - 2363 (3562)
[subject] 1038 - 3425 (7480)
(14 hsp)		 0.0 2059   51% Polyketide synthase gfsA Streptomyces graminofaciens
59
 D6C473_9ACTO
(D6C473)		 Jump to Meili_00240 
[query] 31 - 2800 (3562)
[subject] 2581 - 5484 (5987)
(11 hsp)		 0.0 2057   45% Modular polyketide synthase meiA2 Streptomyces nanchangensis
60
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 29 - 2775 (3562)
[subject] 2620 - 5586 (6171)
(10 hsp)		 0.0 2055   46% Polyketide synthase type I slgA1 Streptomyces lydicus
61
 B4VB12_9ACTO
(B4VB12)		 
[query] 1 - 2357 (3562)
[subject] 1 - 2473 (3203)
(4 hsp)		 0.0 2045   50% Polyketide synthase type I SSAG_04922 Streptomyces sp. Mg1
62
 D9WQ82_9ACTO
(D9WQ82)		 
[query] 1 - 2357 (3562)
[subject] 2 - 2460 (3199)
(4 hsp)		 0.0 2043   50% Erythronolide synthase, modules 1 and 2 SSOG_05756 Streptomyces himastatinicus ATCC 53653
63
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 4 - 2357 (3562)
[subject] 12 - 2466 (3192)
(4 hsp)		 0.0 2025   51% NysB nysB Streptomyces noursei
64
 B4VAJ6_9ACTO
(B4VAJ6)		 
[query] 31 - 2511 (3562)
[subject] 1016 - 3546 (3605)
(6 hsp)		 0.0 2018   50% Polyketide synthase subunit SSAG_04835 Streptomyces sp. Mg1
65
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 25 - 2355 (3562)
[subject] 1561 - 3963 (4685)
(7 hsp)		 0.0 2017   51% Modular polyketide synthase olmA6
SAV2896
SAV_2896		 Streptomyces avermitilis
66
 E0KFI7_STRVO
(E0KFI7)		 
[query] 28 - 2656 (3562)
[subject] 1819 - 4500 (8538)
(15 hsp)		 0.0 2016   47% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
67
 B1W487_STRGG
(B1W487)		 
[query] 2 - 2355 (3562)
[subject] 3 - 2445 (3188)
(4 hsp)		 0.0 2006   50% Putative type-I PKS pks1-3
SGR_6075		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
68
 Q0ILD0_9ACTO
(Q0ILD0)		 
[query] 1 - 2828 (3562)
[subject] 1 - 2941 (3593)
(4 hsp)		 0.0 1996   44% NlmA7 nlmA7 Streptomyces nanchangensis
69
 D5ZU01_9ACTO
(D5ZU01)		 
[query] 31 - 2800 (3562)
[subject] 1577 - 4341 (4790)
(6 hsp)		 0.0 1992   46% Nodular polyketide synthase SSFG_00090 Streptomyces ghanaensis ATCC 14672
70
 D9WQ74_9ACTO
(D9WQ74)		 
[query] 1 - 2819 (3562)
[subject] 1 - 2963 (3286)
(4 hsp)		 0.0 1991   44% Modular polyketide synthase SSOG_05748 Streptomyces himastatinicus ATCC 53653
71
 D9WQ70_9ACTO
(D9WQ70)		 
[query] 28 - 2664 (3562)
[subject] 820 - 3499 (5483)
(11 hsp)		 0.0 1987   46% Modular polyketide synthase SSOG_05744 Streptomyces himastatinicus ATCC 53653
72
 Q82QT4_STRAW
(Q82QT4)		 
[query] 31 - 2806 (3562)
[subject] 1046 - 3897 (7746)
(15 hsp)		 0.0 1986   45% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
73
 Q93H87_STRAW
(Q93H87)		 
[query] 31 - 2806 (3562)
[subject] 1046 - 3897 (6048)
(12 hsp)		 0.0 1986   45% Modular polyketide synthase pteA1 Streptomyces avermitilis
74
 Q52V46_9ACTO
(Q52V46)		 
[query] 31 - 2801 (3562)
[subject] 1689 - 4594 (8147)
(14 hsp)		 0.0 1977   46% Polyketide synthase type I Streptomyces aizunensis
75
 A0ACI3_STRAM
(A0ACI3)		 
[query] 27 - 2808 (3562)
[subject] 2067 - 4998 (5447)
(7 hsp)		 0.0 1976   45% Putative type I modular polyketide synthase SAMR0477 Streptomyces ambofaciens ATCC 23877
76
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 31 - 2355 (3562)
[subject] 1062 - 3420 (4150)
(8 hsp)		 0.0 1971   52% 8,8a-deoxyoleandolide synthase 1 oleAI Streptomyces antibioticus
77
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 1 - 2411 (3562)
[subject] 6 - 2527 (3190)
(4 hsp)		 0.0 1969   48% AmphB amphB Streptomyces nodosus
78
 Q52V53_9ACTO
(Q52V53)		 
[query] 1 - 2800 (3562)
[subject] 1 - 2962 (5207)
(7 hsp)		 0.0 1968   44% Polyketide synthase type I Streptomyces aizunensis
79
 Q9ZGI5_9ACTO
(Q9ZGI5)		 Jump to Pikro_00030 
[query] 31 - 2800 (3562)
[subject] 1109 - 4082 (4613)
(8 hsp)		 0.0 1951   45% Type I polyketide synthase PikAI pikAI Streptomyces venezuelae
80
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 27 - 2800 (3562)
[subject] 5031 - 7914 (10873)
(16 hsp)		 0.0 1951   44% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
81
 A8L4A9_FRASN
(A8L4A9)		 
[query] 33 - 2626 (3562)
[subject] 136 - 2938 (3158)
(5 hsp)		 0.0 1950   47% Erythronolide synthase Franean1_3887 Frankia sp. (strain EAN1pec) 2.3.1.94
82
 B4VB01_9ACTO
(B4VB01)		 
[query] 28 - 2676 (3562)
[subject] 973 - 3635 (3636)
(6 hsp)		 0.0 1945   46% Polyketide synthase type I SSAG_04911 Streptomyces sp. Mg1
83
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 4 - 2365 (3562)
[subject] 8 - 2457 (3175)
(4 hsp)		 0.0 1944   50% CppB cppB Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
84
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 6 - 2805 (3562)
[subject] 2252 - 5133 (10827)
(17 hsp)		 0.0 1944   45% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
85
 B1W485_STRGG
(B1W485)		 
[query] 31 - 2803 (3562)
[subject] 1776 - 4668 (5136)
(9 hsp)		 0.0 1935   45% Putative type-I PKS pks1-1
SGR_6073		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
86
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 6 - 2800 (3562)
[subject] 2732 - 5542 (9648)
(14 hsp)		 0.0 1934   46% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
87
 Q52V44_9ACTO
(Q52V44)		 
[query] 26 - 2800 (3562)
[subject] 3355 - 6275 (6751)
(11 hsp)		 0.0 1933   45% Polyketide synthase type I Streptomyces aizunensis
88
 Q0ILD1_9ACTO
(Q0ILD1)		 
[query] 6 - 2355 (3562)
[subject] 3 - 2419 (4635)
(7 hsp)		 0.0 1931   50% NlmA6 nlmA6 Streptomyces nanchangensis
89
 E4NJF2_KITSK
(E4NJF2)		 
[query] 1 - 2355 (3562)
[subject] 1 - 2474 (5004)
(8 hsp)		 0.0 1930   50% Modular polyketide synthase BFAS2 bfmA2
KSE_73450		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
90
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1027 - 3503 (3562)
[subject] 3889 - 6471 (6532)
(10 hsp)		 0.0 1929   47% Polyketide synthase pldAI Streptomyces platensis
91
 C5HV14_STRAT
(C5HV14)		 Jump to Indano_00160 
[query] 920 - 3496 (3562)
[subject] 2037 - 4712 (4779)
(6 hsp)		 0.0 1928   47% Polyketide synthase idmL Streptomyces antibioticus
92
 Q93HJ4_STRAW
(Q93HJ4)		 Jump to Oligo_00090 
[query] 29 - 2800 (3562)
[subject] 1466 - 4380 (4840)
(6 hsp)		 0.0 1922   46% Modular polyketide synthase
OlmA2 protein		 olmA2
SAV2898
SAV_2898		 Streptomyces avermitilis
93
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 31 - 2801 (3562)
[subject] 9662 - 12603 (16990)
(20 hsp)		 0.0 1922   43% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
94
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 6 - 2800 (3562)
[subject] 2616 - 5426 (9528)
(14 hsp)		 0.0 1919   46% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
95
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 31 - 2363 (3562)
[subject] 1789 - 4206 (9498)
(16 hsp)		 0.0 1914   51% ScnS2 scnS2 Streptomyces chattanoogensis
96
 Q0ILD3_9ACTO
(Q0ILD3)		 
[query] 29 - 2825 (3562)
[subject] 1466 - 4368 (4799)
(6 hsp)		 0.0 1913   45% NlmA2 nlmA2 Streptomyces nanchangensis
97
 O33954_STRFR
(O33954)		 
[query] 7 - 2825 (3562)
[subject] 1031 - 4028 (4472)
(8 hsp)		 0.0 1913   46% Tylactone synthase starter module and modules 1 & 2 tylG Streptomyces fradiae
Streptomyces roseoflavus
98
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 31 - 2801 (3562)
[subject] 3356 - 6303 (14130)
(22 hsp)		 0.0 1912   43% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
99
 Q93H83_STRAW
(Q93H83)		 
[query] 2 - 2355 (3562)
[subject] 3 - 2414 (3352)
(4 hsp)		 0.0 1912   48% Modular polyketide synthase pteA5
SAV415
SAV_415		 Streptomyces avermitilis
100
 E0KBI2_STRVO
(E0KBI2)		 
[query] 31 - 2355 (3562)
[subject] 1760 - 4195 (4930)
(9 hsp)		 0.0 1907   48% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q9F829_9ACTO
(Q9F829)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3562 (3562)
 0.0 6928   100%
Product
Megalomicin 6-deoxyerythronolide B synthase 2
Gene
megAII
Organism
Micromonospora megalomicea subsp. nigra
1uniprot[Pubmed] 10972798 [Medline] 20430101
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
2
 A4F7P0_SACEN
(A4F7P0)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5086   76%
Product
EryAII Erythromycin polyketide synthase modules 3 and 4
Gene
eryAII
SACE_0723
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
2uniprot[Pubmed] 17719492
Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.(Chem. Biol.) [2007]
[pubmed all]
3
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5086   76%
Product
EryAII
Gene
eryAII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
4
 ERYA2_SACER
(Q03132)		 
[query] 1 - 3562 (3562)
[subject] 1 - 3567 (3567)
 0.0 5064   76%
Product
Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II
DEBS 2
ORF 2
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
2uniprot[Pubmed] 1740151 [Medline] 92155230
6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992]
3uniprot[Pubmed] 1618327
Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992]
4uniprot[Pubmed] 12954331
The structure of docking domains in modular polyketide synthases.(Chem. Biol.) [2003]
[pubmed all]
5
 Q83X70_STRRO
(Q83X70)		 
[query] 1 - 3561 (3562)
[subject] 1 - 3654 (3656)
 0.0 3640   59%
Product
Lankamycin synthase LkmAII
Gene
lkmAII
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
6
 Q5Y9G5_9ACTO
(Q5Y9G5)		 
[query] 4 - 3561 (3562)
[subject] 7 - 3571 (3574)
 0.0 3287   56%
Product
Polyketide synthase modules 3 and 4
Gene
eryAII
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
8
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 31 - 3483 (3562)
[subject] 1734 - 5374 (7178)
(11 hsp)		 0.0 2833   49%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
9
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 31 - 3483 (3562)
[subject] 1729 - 5298 (7102)
(11 hsp)		 0.0 2821   50%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
14
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 17 - 3557 (3562)
[subject] 3 - 3732 (3734)
 0.0 2732   48%
Product
Putative type I polyketide synthase
Gene
gerSIII
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
16
 Q9ZGI4_9ACTO
(Q9ZGI4)		 Jump to Pikro_00040 
[query] 3 - 3557 (3562)
[subject] 5 - 3735 (3739)
 0.0 2676   48%
Product
Type I polyketide synthase PikAII
Gene
pikAII
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
17
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 28 - 3482 (3562)
[subject] 5941 - 9538 (11604)
(17 hsp)		 0.0 2662   47%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
18
 A0ACH1_STRAM
(A0ACH1)		 
[query] 2 - 3482 (3562)
[subject] 3 - 3570 (8154)
(9 hsp)		 0.0 2613   48%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
20
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 30 - 3478 (3562)
[subject] 2077 - 5632 (5710)
(5 hsp)		 0.0 2444   46%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
21
 D7C2B8_STRBB
(D7C2B8)		 
[query] 2 - 3483 (3562)
[subject] 3 - 3621 (7498)
(5 hsp)		 0.0 2444   46%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
22
 B1W4J4_STRGG
(B1W4J4)		 
[query] 1 - 3557 (3562)
[subject] 7 - 3721 (3723)
 0.0 2443   45%
Product
Putative type-I PKS
Gene
pks2-4
SGR_6182
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
23
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 29 - 3557 (3562)
[subject] 2465 - 6143 (6146)
(7 hsp)		 0.0 2430   46%
Product
Modular polyketide synthase
Gene
olmA1
SAV2899
SAV_2899
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
24
 B1W489_STRGG
(B1W489)		 
[query] 9 - 3482 (3562)
[subject] 18 - 3654 (3734)
 0.0 2429   46%
Product
Putative type-I PKS
Gene
pks1-5
SGR_6077
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
25
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 7 - 3562 (3562)
[subject] 4088 - 7771 (7771)
(6 hsp)		 0.0 2368   44%
Product
FscE
Gene
fscE
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
26
 B1W4J2_STRGG
(B1W4J2)		 
[query] 31 - 3484 (3562)
[subject] 1580 - 5252 (5343)
(4 hsp)		 0.0 2363   45%
Product
Putative type-I PKS
Gene
pks2-2
SGR_6180
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
27
 A0ACI2_STRAM
(A0ACI2)		 
[query] 4 - 3556 (3562)
[subject] 6 - 3562 (3565)
 0.0 2338   46%
Product
Putative modular polyketide synthase
Gene
SAMR0476
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
28
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 1 - 2656 (3562)
[subject] 1 - 2790 (3816)
(4 hsp)		 0.0 2315   51%
Product
8,8a-deoxyoleandolide synthase 2
Gene
oleAII
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
29
 Q83WE8_MICGR
(Q83WE8)		 
[query] 1 - 3556 (3562)
[subject] 1 - 3646 (3649)
 0.0 2312   45%
Product
Protomycinolide IV synthase 3
Gene
mycAIII
Organism
Micromonospora griseorubida
1uniprot[Pubmed] 12583909 [Medline] 22472038
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
30
 C9YYI3_STRSW
(C9YYI3)		 
[query] 31 - 2801 (3562)
[subject] 1624 - 4544 (5001)
(7 hsp)		 0.0 2278   49%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
32
 D7BSM1_STRBB
(D7BSM1)		 
[query] 3 - 2800 (3562)
[subject] 4 - 2975 (3439)
(4 hsp)		 0.0 2247   48%
Product
Type I polyketide synthase
Gene
nanA8
SBI_08400
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
33
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 3 - 2800 (3562)
[subject] 17 - 2991 (3455)
(4 hsp)		 0.0 2246   48%
Product
NanA8
Gene
nanA8
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
34
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 31 - 2801 (3562)
[subject] 1625 - 4547 (5006)
(7 hsp)		 0.0 2245   49%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
35
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 31 - 2800 (3562)
[subject] 1067 - 3812 (5721)
(10 hsp)		 0.0 2241   50%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
36
 F1DI32_9ACTO
(F1DI32)		 
[query] 1 - 2825 (3562)
[subject] 14 - 2983 (3378)
(4 hsp)		 0.0 2233   46%
Product
TrdAII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
38
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 31 - 2800 (3562)
[subject] 1061 - 3805 (5712)
(10 hsp)		 0.0 2230   50%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
39
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 1 - 2825 (3562)
[subject] 1 - 2970 (3365)
(4 hsp)		 0.0 2212   46%
Product
TamAII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
40
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 1 - 2773 (3562)
[subject] 19 - 3013 (3479)
(4 hsp)		 0.0 2199   47%
Product
Polyketide synthase type I
Gene
slgA2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
42
 B1W4J5_STRGG
(B1W4J5)		 
[query] 1 - 2811 (3562)
[subject] 1 - 2919 (3579)
(4 hsp)		 0.0 2167   48%
Product
Putative type-I PKS
Gene
pks2-5
SGR_6183
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
43
 Q5SFB2_STRBI
(Q5SFB2)		 Jump to Chalc_00230 
[query] 2 - 2661 (3562)
[subject] 8 - 2770 (3788)
(4 hsp)		 0.0 2153   49%
Product
Polyketide synthase subunit
Gene
chmGIII
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
44
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 31 - 2806 (3562)
[subject] 1063 - 3957 (4441)
(8 hsp)		 0.0 2145   48%
Product
Polyketide synthase subunit
Gene
chmGI
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
45
 E4NJF4_KITSK
(E4NJF4)		 
[query] 9 - 2801 (3562)
[subject] 3 - 2965 (3436)
(4 hsp)		 0.0 2121   47%
Product
Modular polyketide synthase BFAS4
Gene
bfmA4
KSE_73470
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
46
 F1DI31_9ACTO
(F1DI31)		 
[query] 29 - 2800 (3562)
[subject] 2531 - 5366 (5829)
(10 hsp)		 0.0 2120   47%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
47
 A8L4B1_FRASN
(A8L4B1)		 
[query] 1 - 2626 (3562)
[subject] 1 - 2853 (3493)
(4 hsp)		 0.0 2116   48%
Product
Beta-ketoacyl synthase
Gene
Franean1_3889
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
48
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 31 - 2806 (3562)
[subject] 1008 - 3900 (4387)
(8 hsp)		 0.0 2115   47%
Product
Putative type I polyketide synthase
Gene
gerSI
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
50
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 29 - 2800 (3562)
[subject] 2531 - 5365 (5828)
(10 hsp)		 0.0 2114   47%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
51
 E2Q518_STRCL
(E2Q518)		 
[query] 3 - 2812 (3562)
[subject] 16 - 3121 (3596)
(4 hsp)		 0.0 2100   46%
Product
Modular polyketide synthase
Gene
SCLAV_0012
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
52
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1 - 2800 (3562)
[subject] 1 - 2959 (7111)
(10 hsp)		 0.0 2092   46%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
54
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 26 - 2825 (3562)
[subject] 3657 - 6632 (7026)
(11 hsp)		 0.0 2078   45%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
55
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 1 - 2828 (3562)
[subject] 1 - 2954 (3613)
(4 hsp)		 0.0 2076   46%
Product
Modular polyketide synthase
Gene
olmA7
SAV2895
SAV_2895
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
56
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 25 - 2808 (3562)
[subject] 1583 - 4572 (5277)
(6 hsp)		 0.0 2063   45%
Product
Modular polyketide synthase
Gene
meiA4
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
57
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 1 - 2828 (3562)
[subject] 1 - 2854 (3264)
(4 hsp)		 0.0 2060   46%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
58
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 31 - 2363 (3562)
[subject] 1038 - 3425 (7480)
(14 hsp)		 0.0 2059   51%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
59
 D6C473_9ACTO
(D6C473)		 Jump to Meili_00240 
[query] 31 - 2800 (3562)
[subject] 2581 - 5484 (5987)
(11 hsp)		 0.0 2057   45%
Product
Modular polyketide synthase
Gene
meiA2
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
60
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 29 - 2775 (3562)
[subject] 2620 - 5586 (6171)
(10 hsp)		 0.0 2055   46%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
63
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 4 - 2357 (3562)
[subject] 12 - 2466 (3192)
(4 hsp)		 0.0 2025   51%
Product
NysB
Gene
nysB
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
65
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 25 - 2355 (3562)
[subject] 1561 - 3963 (4685)
(7 hsp)		 0.0 2017   51%
Product
Modular polyketide synthase
Gene
olmA6
SAV2896
SAV_2896
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
67
 B1W487_STRGG
(B1W487)		 
[query] 2 - 2355 (3562)
[subject] 3 - 2445 (3188)
(4 hsp)		 0.0 2006   50%
Product
Putative type-I PKS
Gene
pks1-3
SGR_6075
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
72
 Q82QT4_STRAW
(Q82QT4)		 
[query] 31 - 2806 (3562)
[subject] 1046 - 3897 (7746)
(15 hsp)		 0.0 1986   45%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
73
 Q93H87_STRAW
(Q93H87)		 
[query] 31 - 2806 (3562)
[subject] 1046 - 3897 (6048)
(12 hsp)		 0.0 1986   45%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
74
 Q52V46_9ACTO
(Q52V46)		 
[query] 31 - 2801 (3562)
[subject] 1689 - 4594 (8147)
(14 hsp)		 0.0 1977   46%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
75
 A0ACI3_STRAM
(A0ACI3)		 
[query] 27 - 2808 (3562)
[subject] 2067 - 4998 (5447)
(7 hsp)		 0.0 1976   45%
Product
Putative type I modular polyketide synthase
Gene
SAMR0477
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
76
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 31 - 2355 (3562)
[subject] 1062 - 3420 (4150)
(8 hsp)		 0.0 1971   52%
Product
8,8a-deoxyoleandolide synthase 1
Gene
oleAI
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
77
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 1 - 2411 (3562)
[subject] 6 - 2527 (3190)
(4 hsp)		 0.0 1969   48%
Product
AmphB
Gene
amphB
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
3uniprot[Pubmed] 20696392
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010]
[pubmed all]
78
 Q52V53_9ACTO
(Q52V53)		 
[query] 1 - 2800 (3562)
[subject] 1 - 2962 (5207)
(7 hsp)		 0.0 1968   44%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
79
 Q9ZGI5_9ACTO
(Q9ZGI5)		 Jump to Pikro_00030 
[query] 31 - 2800 (3562)
[subject] 1109 - 4082 (4613)
(8 hsp)		 0.0 1951   45%
Product
Type I polyketide synthase PikAI
Gene
pikAI
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
81
 A8L4A9_FRASN
(A8L4A9)		 
[query] 33 - 2626 (3562)
[subject] 136 - 2938 (3158)
(5 hsp)		 0.0 1950   47%
Product
Erythronolide synthase
Gene
Franean1_3887
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
83
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 4 - 2365 (3562)
[subject] 8 - 2457 (3175)
(4 hsp)		 0.0 1944   50%
Product
CppB
Gene
cppB
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
84
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 6 - 2805 (3562)
[subject] 2252 - 5133 (10827)
(17 hsp)		 0.0 1944   45%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
85
 B1W485_STRGG
(B1W485)		 
[query] 31 - 2803 (3562)
[subject] 1776 - 4668 (5136)
(9 hsp)		 0.0 1935   45%
Product
Putative type-I PKS
Gene
pks1-1
SGR_6073
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
86
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 6 - 2800 (3562)
[subject] 2732 - 5542 (9648)
(14 hsp)		 0.0 1934   46%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
87
 Q52V44_9ACTO
(Q52V44)		 
[query] 26 - 2800 (3562)
[subject] 3355 - 6275 (6751)
(11 hsp)		 0.0 1933   45%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
89
 E4NJF2_KITSK
(E4NJF2)		 
[query] 1 - 2355 (3562)
[subject] 1 - 2474 (5004)
(8 hsp)		 0.0 1930   50%
Product
Modular polyketide synthase BFAS2
Gene
bfmA2
KSE_73450
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
90
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1027 - 3503 (3562)
[subject] 3889 - 6471 (6532)
(10 hsp)		 0.0 1929   47%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
91
 C5HV14_STRAT
(C5HV14)		 Jump to Indano_00160 
[query] 920 - 3496 (3562)
[subject] 2037 - 4712 (4779)
(6 hsp)		 0.0 1928   47%
Product
Polyketide synthase
Gene
idmL
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
92
 Q93HJ4_STRAW
(Q93HJ4)		 Jump to Oligo_00090 
[query] 29 - 2800 (3562)
[subject] 1466 - 4380 (4840)
(6 hsp)		 0.0 1922   46%
Product
Modular polyketide synthase
OlmA2 protein
Gene
olmA2
SAV2898
SAV_2898
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
93
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 31 - 2801 (3562)
[subject] 9662 - 12603 (16990)
(20 hsp)		 0.0 1922   43%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
94
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 6 - 2800 (3562)
[subject] 2616 - 5426 (9528)
(14 hsp)		 0.0 1919   46%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
95
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 31 - 2363 (3562)
[subject] 1789 - 4206 (9498)
(16 hsp)		 0.0 1914   51%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
97
 O33954_STRFR
(O33954)		 
[query] 7 - 2825 (3562)
[subject] 1031 - 4028 (4472)
(8 hsp)		 0.0 1913   46%
Product
Tylactone synthase starter module and modules 1 & 2
Gene
tylG
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 17719489
A tylosin ketoreductase reveals how chirality is determined in polyketides.(Chem. Biol.) [2007]
98
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 31 - 2801 (3562)
[subject] 3356 - 6303 (14130)
(22 hsp)		 0.0 1912   43%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
99
 Q93H83_STRAW
(Q93H83)		 
[query] 2 - 2355 (3562)
[subject] 3 - 2414 (3352)
(4 hsp)		 0.0 1912   48%
Product
Modular polyketide synthase
Gene
pteA5
SAV415
SAV_415
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]