| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
O30766_9ACTO (O30766) |
|
|
0.0 |
7091 |
100% |
|
- Product
- Polyketide synthase modules 4 and 5
- Gene
- nidA3
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
6
|
D7CC08_STRBB (D7CC08) |
|
(9 hsp) |
0.0 |
2067 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
7
|
D7CC07_STRBB (D7CC07) |
|
(8 hsp) |
0.0 |
2066 |
51% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-1
SBI_01381
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
8
|
B6ZIR2_STRPT (B6ZIR2) |
|
(11 hsp) |
0.0 |
2055 |
51% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
9
|
C5HV14_STRAT (C5HV14) |
|
(8 hsp) |
0.0 |
2048 |
50% |
|
- Product
- Polyketide synthase
- Gene
- idmL
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
10
|
Q9KIV3_STRAT (Q9KIV3) |
|
(5 hsp) |
0.0 |
2035 |
49% |
|
- Product
- 8,8a-deoxyoleandolide synthase 2
- Gene
- oleAII
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
13
|
C9YYI2_STRSW (C9YYI2) |
|
(4 hsp) |
0.0 |
2021 |
50% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
14
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(13 hsp) |
0.0 |
2002 |
51% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
16
|
A0FCL3_STRVO (A0FCL3) |
|
(20 hsp) |
0.0 |
1981 |
50% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
17
|
Q9ZGI4_9ACTO (Q9ZGI4) |
|
(4 hsp) |
0.0 |
1974 |
50% |
|
- Product
- Type I polyketide synthase PikAII
- Gene
- pikAII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
20
|
A0ACH1_STRAM (A0ACH1) |
|
(14 hsp) |
0.0 |
1942 |
51% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0465
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
21
|
A1YAM7_AMYOR (A1YAM7) |
|
(8 hsp) |
0.0 |
1922 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
22
|
Q6W5P9_9ACTO (Q6W5P9) |
|
(9 hsp) |
0.0 |
1915 |
50% |
|
- Product
- FscB
- Gene
- fscB
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
25
|
D7BUT1_STRBB (D7BUT1) |
|
(5 hsp) |
0.0 |
1881 |
53% |
|
- Product
- Putative type-I PKS
- Gene
- SBI_00151
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
26
|
Q83WE8_MICGR (Q83WE8) |
|
(4 hsp) |
0.0 |
1877 |
49% |
|
- Product
- Protomycinolide IV synthase 3
- Gene
- mycAIII
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
28
|
Q9ADL6_SORCE (Q9ADL6) |
|
(9 hsp) |
0.0 |
1865 |
46% |
|
- Product
- Soraphen polyketide synthase A
- Gene
- sorA
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] |
|
29
|
E0D203_9ACTO (E0D203) |
|
(9 hsp) |
0.0 |
1865 |
54% |
|
- Product
- Polyketide synthase
- Gene
- gfsB
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
30
|
ERYA2_SACER (Q03132) |
|
(5 hsp) |
0.0 |
1863 |
47% |
|
- Product
- Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II DEBS 2 ORF 2
- Gene
- eryA
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 2024119 [Medline] 91220065 Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991] | 2uniprot[Pubmed] 1740151 [Medline] 92155230 6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992] | 3uniprot[Pubmed] 1618327 Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992] | 4uniprot[Pubmed] 12954331 The structure of docking domains in modular polyketide synthases.(Chem. Biol.) [2003] | [pubmed all]
|
31
|
F1CT51_9ACTO (F1CT51) |
|
(9 hsp) |
0.0 |
1862 |
48% |
|
- Product
- GdmAI
- Gene
- gdmAI
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
32
|
Q27W72_STRVO (Q27W72) |
|
(4 hsp) |
0.0 |
1853 |
48% |
|
- Product
- NigAIII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
34
|
A1YAM6_AMYOR (A1YAM6) |
|
(8 hsp) |
0.0 |
1853 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
35
|
Q9F829_9ACTO (Q9F829) |
|
(6 hsp) |
0.0 |
1847 |
47% |
|
- Product
- Megalomicin 6-deoxyerythronolide B synthase 2
- Gene
- megAII
- Organism
- Micromonospora megalomicea subsp. nigra
|
1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000] |
|
37
|
B6ZK64_STRLS (B6ZK64) |
|
(7 hsp) |
0.0 |
1842 |
48% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd11
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
38
|
A4FDM8_SACEN (A4FDM8) |
|
(6 hsp) |
0.0 |
1836 |
49% |
|
- Product
- Modular polyketide synthase-
- Gene
- SACE_2875
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
39
|
Q53840_SORCE (Q53840) |
|
(16 hsp) |
0.0 |
1835 |
47% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
40
|
Q1L0T2_STRHY (Q1L0T2) |
|
(8 hsp) |
0.0 |
1833 |
48% |
|
- Product
- GelA
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
42
|
Q84G24_STRHY (Q84G24) |
|
(8 hsp) |
0.0 |
1825 |
47% |
|
- Product
- GdmAI
- Gene
- gdmAI
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
44
|
C0SMW3_9ACTO (C0SMW3) |
|
(8 hsp) |
0.0 |
1817 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmI
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
45
|
D2SZ11_MICEC (D2SZ11) |
|
(5 hsp) |
0.0 |
1816 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Micromonospora echinospora subsp. challisensis
|
1uniprot[Pubmed] 19680283 TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009] |
|
49
|
Q0R4M7_STRAT (Q0R4M7) |
|
(6 hsp) |
0.0 |
1808 |
45% |
|
- Product
- ChlA2
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
50
|
Q49BE1_STRHY (Q49BE1) |
|
(9 hsp) |
0.0 |
1805 |
47% |
|
- Product
- HbmAI
- Gene
- hbmAI
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
52
|
Q846X4_STRCM (Q846X4) |
|
(6 hsp) |
0.0 |
1801 |
47% |
|
- Product
- Monensin polyketide synthase modules 3 and 4
- Gene
- monAIII
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
53
|
Q93HJ3_STRAW (Q93HJ3) |
|
(6 hsp) |
0.0 |
1800 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA3
SAV2897 SAV_2897
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
54
|
Q7WTF3_9ACTO (Q7WTF3) |
|
(4 hsp) |
0.0 |
1799 |
47% |
|
- Product
- NanA3
- Gene
- nanA3
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
55
|
B6ZIR4_STRPT (B6ZIR4) |
|
(4 hsp) |
0.0 |
1799 |
48% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
56
|
Q27W59_STRVO (Q27W59) |
|
(3 hsp) |
0.0 |
1796 |
51% |
|
- Product
- NIGAVIII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
58
|
C0SMW2_9ACTO (C0SMW2) |
|
(9 hsp) |
0.0 |
1791 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmH
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
59
|
Q6JHN6_9PSEU (Q6JHN6) |
|
(11 hsp) |
0.0 |
1790 |
47% |
|
- Product
- ObsC
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
60
|
D7C2B8_STRBB (D7C2B8) |
|
(12 hsp) |
0.0 |
1787 |
47% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
61
|
Q27W69_STRVO (Q27W69) |
|
(5 hsp) |
0.0 |
1785 |
51% |
|
- Product
- NigAV
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
62
|
B5L6M3_MICCH (B5L6M3) |
|
(6 hsp) |
0.0 |
1780 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
63
|
E2Q519_STRCL (E2Q519) |
|
(5 hsp) |
0.0 |
1773 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0013
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
64
|
Q7VES2_MYCBO (Q7VES2) |
|
(5 hsp) |
0.0 |
1773 |
46% |
|
- Product
- Probable polyketide synthase pks12
- Gene
- pks12
Mb2074c
- Organism
- Mycobacterium bovis
|
1uniprot[Pubmed] 12788972 [Medline] 22709107 The complete genome sequence of Mycobacterium bovis.(Proc. Natl. Acad. Sci. U.S.A.) [2003] |
|
66
|
Q73Z07_MYCPA (Q73Z07) |
|
(4 hsp) |
0.0 |
1768 |
46% |
|
- Product
- Pks12
- Gene
- pks12
MAP_1796c
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
67
|
D6C477_9ACTO (D6C477) |
|
(9 hsp) |
0.0 |
1767 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA3
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
69
|
C1APW8_MYCBT (C1APW8) |
|
(5 hsp) |
0.0 |
1766 |
46% |
|
- Product
- Putative polyketide synthase
- Gene
- pks12
JTY_2062
- Organism
- Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
|
1uniprot[Pubmed] 19200449 Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009] |
|
70
|
A1KK94_MYCBP (A1KK94) |
|
(5 hsp) |
0.0 |
1766 |
46% |
|
- Product
- Probable polyketide synthase pks12
- Gene
- pks12
BCG_2067c
- Organism
- Mycobacterium bovis (strain BCG / Pasteur 1173P2)
|
1uniprot[Pubmed] 17372194 Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007] |
|
71
|
A0PQM7_MYCUA (A0PQM7) |
|
(6 hsp) |
0.0 |
1766 |
45% |
|
- Product
- Polyketide synthase, Pks12
- Gene
- pks12
MUL_2266
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 17210928 Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007] |
|
81
|
D7C432_STRBB (D7C432) |
|
(11 hsp) |
0.0 |
1761 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- milA3
SBI_00733
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
82
|
Q70HZ8_9ACTO (Q70HZ8) |
|
(3 hsp) |
0.0 |
1761 |
50% |
|
- Product
- Borrelidin polyketide synthase, type I
- Gene
- borA5
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
83
|
O53490_MYCTU (O53490) |
|
(5 hsp) |
0.0 |
1760 |
45% |
|
- Product
- Probable polyketide synthase pks12
- Gene
- pks12
Rv2048c
- Organism
- Mycobacterium tuberculosis
|
1uniprot[Pubmed] 9634230 [Medline] 98295987 Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.(Nature) [1998] |
|
84
|
B2HF44_MYCMM (B2HF44) |
|
(5 hsp) |
0.0 |
1759 |
45% |
|
- Product
- Polyketide synthase, Pks12
- Gene
- pks12
MMAR_3025
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
85
|
Q93NX8_9ACTO (Q93NX8) |
|
(10 hsp) |
0.0 |
1759 |
47% |
|
- Product
- AmphJ
- Gene
- amphJ
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
86
|
D7BSM2_STRBB (D7BSM2) |
|
(3 hsp) |
0.0 |
1758 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- nanA11
SBI_08401
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
88
|
Q7D7J7_MYCTU (Q7D7J7) |
|
(5 hsp) |
0.0 |
1756 |
45% |
|
- Product
- Polyketide synthase
- Gene
- MT2108
- Organism
- Mycobacterium tuberculosis
|
1uniprot[Pubmed] 12218036 [Medline] 22206494 Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.(J. Bacteriol.) [2002] |
|
90
|
Q93NW6_9ACTO (Q93NW6) |
|
(17 hsp) |
0.0 |
1753 |
48% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
92
|
B3TMP1_9ACTO (B3TMP1) |
|
(6 hsp) |
0.0 |
1748 |
52% |
|
- Product
- Polyketide synthase
- Gene
- KijS4
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
93
|
Q54299_STRHY (Q54299) |
|
(12 hsp) |
0.0 |
1748 |
45% |
|
- Product
- Polyketide synthase
- Gene
- rapC
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995] | 2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996] | 3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996] | [pubmed all]
|
94
|
C0SMW4_9ACTO (C0SMW4) |
|
(21 hsp) |
0.0 |
1743 |
47% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
95
|
Q7WTD7_9ACTO (Q7WTD7) |
|
(3 hsp) |
0.0 |
1741 |
51% |
|
- Product
- NanA11
- Gene
- nanA11
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
98
|
B1W4J4_STRGG (B1W4J4) |
|
(4 hsp) |
0.0 |
1736 |
46% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-4
SGR_6182
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
99
|
Q83X70_STRRO (Q83X70) |
|
(5 hsp) |
0.0 |
1735 |
46% |
|
- Product
- Lankamycin synthase LkmAII
- Gene
- lkmAII
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|