| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
D8HZ84_AMYMU (D8HZ84) |
|
|
0.0 |
3431 |
100% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifC
AMED_0619
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
2
|
O52790_AMYMD (O52790) |
|
|
0.0 |
3431 |
100% |
|
- Product
- RifC
Rifamycin polyketide synthase, type 1
- Gene
- rifC
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
4
|
D8HZ83_AMYMU (D8HZ83) |
|
(3 hsp) |
0.0 |
2153 |
69% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifB
AMED_0618
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
6
|
O52545_AMYMD (O52545) |
|
(3 hsp) |
0.0 |
2150 |
71% |
|
- Product
- RifB
- Gene
- rifB
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
7
|
D8HZ86_AMYMU (D8HZ86) |
|
(2 hsp) |
0.0 |
2132 |
69% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifE
AMED_0621
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
8
|
O54593_AMYMD (O54593) |
|
(2 hsp) |
0.0 |
2132 |
69% |
|
- Product
- RifE
Rifamycin polyketide synthase, type 1
- Gene
- rifE
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
11
|
D8HZ85_AMYMU (D8HZ85) |
|
|
0.0 |
2058 |
66% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifD
AMED_0620
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
12
|
O54591_AMYMD (O54591) |
|
|
0.0 |
2058 |
66% |
|
- Product
- RifD
Rifamycin polyketide synthase, type 1
- Gene
- rifD
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
14
|
F8QPG0_9ACTO (F8QPG0) |
|
(3 hsp) |
0.0 |
1997 |
65% |
|
- Product
- Polyketide synthase
- Gene
- natC
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
15
|
F8QPG1_9ACTO (F8QPG1) |
|
(2 hsp) |
0.0 |
1941 |
62% |
|
- Product
- Polyketide synthase
- Gene
- natD
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
16
|
F8QPF9_9ACTO (F8QPF9) |
|
(3 hsp) |
0.0 |
1934 |
61% |
|
- Product
- Polyketide synthase
- Gene
- natB
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
17
|
F8QPG2_9ACTO (F8QPG2) |
|
(2 hsp) |
0.0 |
1854 |
62% |
|
- Product
- Polyketide synthase
- Gene
- natE
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
19
|
Q2PC52_STRAH (Q2PC52) |
|
(3 hsp) |
0.0 |
1669 |
55% |
|
- Product
- Putative polyketide synthase
- Gene
- rubB
- Organism
- Streptomyces achromogenes subsp. rubradiris
|
1uniprot[Pubmed] 9387157 [Medline] 98048398 Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997] | 2uniprot[Pubmed] 12889805 [Medline] 22771458 Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003] | [pubmed all]
|
20
|
F8QPF8_9ACTO (F8QPF8) |
|
(6 hsp) |
0.0 |
1619 |
57% |
|
- Product
- Polyketide synthase
- Gene
- natA
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
23
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(7 hsp) |
0.0 |
1592 |
52% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
24
|
F1DI31_9ACTO (F1DI31) |
|
(7 hsp) |
0.0 |
1591 |
52% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
31
|
Q1L0T1_STRHY (Q1L0T1) |
|
(3 hsp) |
0.0 |
1555 |
51% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
32
|
C9YYI3_STRSW (C9YYI3) |
|
(5 hsp) |
0.0 |
1555 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
34
|
Q84G23_STRHY (Q84G23) |
|
(3 hsp) |
0.0 |
1553 |
51% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
35
|
Q3S863_9ACTO (Q3S863) |
|
(4 hsp) |
0.0 |
1550 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
37
|
Q1L0T0_STRHY (Q1L0T0) |
|
(3 hsp) |
0.0 |
1546 |
51% |
|
- Product
- GelC
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
39
|
C9YYI2_STRSW (C9YYI2) |
|
(3 hsp) |
0.0 |
1537 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
40
|
C5HV16_STRAT (C5HV16) |
|
(5 hsp) |
0.0 |
1536 |
54% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
41
|
C6WNW1_ACTMD (C6WNW1) |
|
(5 hsp) |
0.0 |
1535 |
54% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2695
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
43
|
F1DI32_9ACTO (F1DI32) |
|
(3 hsp) |
0.0 |
1534 |
51% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
44
|
Q84G22_STRHY (Q84G22) |
|
(3 hsp) |
0.0 |
1533 |
51% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
46
|
Q93H86_STRAW (Q93H86) |
|
(2 hsp) |
0.0 |
1528 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
47
|
Q3S869_9ACTO (Q3S869) |
|
(5 hsp) |
0.0 |
1528 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
48
|
Q82QT5_STRAW (Q82QT5) |
|
(2 hsp) |
0.0 |
1527 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
SAV418 SAV_418
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
49
|
Q06BM4_STRHY (Q06BM4) |
|
(3 hsp) |
0.0 |
1526 |
51% |
|
- Product
- GdmPKS
- Gene
- gdmPKS
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 18214443 The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.(Arch. Microbiol.) [2008] |
|
51
|
C3VLZ7_9ACTO (C3VLZ7) |
|
(2 hsp) |
0.0 |
1526 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaF
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
52
|
F1CT53_9ACTO (F1CT53) |
|
(3 hsp) |
0.0 |
1525 |
51% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
53
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(3 hsp) |
0.0 |
1525 |
51% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
54
|
Q49BE0_STRHY (Q49BE0) |
|
(3 hsp) |
0.0 |
1524 |
50% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
55
|
A4FH85_SACEN (A4FH85) |
|
(5 hsp) |
0.0 |
1521 |
53% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
56
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(5 hsp) |
0.0 |
1521 |
53% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
57
|
F1CT52_9ACTO (F1CT52) |
|
(3 hsp) |
0.0 |
1521 |
50% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
59
|
E0D205_9ACTO (E0D205) |
|
(2 hsp) |
0.0 |
1516 |
50% |
|
- Product
- Polyketide synthase
- Gene
- gfsD
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
62
|
C3VLW9_9ACTO (C3VLW9) |
|
(2 hsp) |
0.0 |
1513 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- becF
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
63
|
Q54297_STRHY (Q54297) |
|
(8 hsp) |
0.0 |
1511 |
52% |
|
- Product
- Polyketide synthase
- Gene
- rapA
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995] | 2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996] | 3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996] | [pubmed all]
|
64
|
C3VLV8_9ACTO (C3VLV8) |
|
(3 hsp) |
0.0 |
1510 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
- becB
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
65
|
Q30CS1_STRAU (Q30CS1) |
|
(2 hsp) |
0.0 |
1508 |
52% |
|
- Product
- LipPks2
- Gene
- lipPks2
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
67
|
A0FCL2_STRVO (A0FCL2) |
|
(6 hsp) |
0.0 |
1506 |
51% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
68
|
C3VLY6_9ACTO (C3VLY6) |
|
(2 hsp) |
0.0 |
1504 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaB
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
69
|
A1YAM8_AMYOR (A1YAM8) |
|
|
0.0 |
1503 |
53% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
70
|
Q0R4M3_STRAT (Q0R4M3) |
|
(3 hsp) |
0.0 |
1502 |
51% |
|
- Product
- ChlA5
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
71
|
D7CC08_STRBB (D7CC08) |
|
(5 hsp) |
0.0 |
1501 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
74
|
Q93NW6_9ACTO (Q93NW6) |
|
(7 hsp) |
0.0 |
1495 |
50% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
76
|
Q54296_STRHY (Q54296) |
|
(7 hsp) |
0.0 |
1490 |
51% |
|
- Product
- Polyketide synthase
- Gene
- rapB
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995] | 2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996] | 3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996] | [pubmed all]
|
77
|
E0D206_9ACTO (E0D206) |
|
(2 hsp) |
0.0 |
1489 |
51% |
|
- Product
- Polyketide synthase
- Gene
- gfsE
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
80
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(6 hsp) |
0.0 |
1488 |
50% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
81
|
B6ZIR3_STRPT (B6ZIR3) |
|
(5 hsp) |
0.0 |
1486 |
52% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
82
|
Q49BD9_STRHY (Q49BD9) |
|
(3 hsp) |
0.0 |
1486 |
50% |
|
- Product
- HbmAIII
- Gene
- hbmAIII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
83
|
Q0R4M8_STRAT (Q0R4M8) |
|
(4 hsp) |
0.0 |
1485 |
51% |
|
- Product
- ChlA1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
84
|
B3TMQ8_9ACTO (B3TMQ8) |
|
(5 hsp) |
0.0 |
1484 |
52% |
|
- Product
- Polyketide synthase
- Gene
- KijS1
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
87
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(4 hsp) |
0.0 |
1478 |
50% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
88
|
C5HV15_STRAT (C5HV15) |
|
(2 hsp) |
0.0 |
1476 |
52% |
|
- Product
- Polyketide synthase
- Gene
- idmM
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
92
|
Q70KH8_9ACTO (Q70KH8) |
|
(2 hsp) |
0.0 |
1474 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
- aurA
- Organism
- Streptomyces thioluteus
|
1uniprot[Pubmed] 14700630 Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster.(Chem. Biol.) [2003] |
|
95
|
A1YAN1_AMYOR (A1YAN1) |
|
|
0.0 |
1472 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
96
|
Q6JHN8_9PSEU (Q6JHN8) |
|
(5 hsp) |
0.0 |
1471 |
52% |
|
- Product
- ObsA
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
97
|
D7BSM1_STRBB (D7BSM1) |
|
(3 hsp) |
0.0 |
1469 |
50% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
98
|
Q2PC83_STRAH (Q2PC83) |
|
(6 hsp) |
0.0 |
1467 |
53% |
|
- Product
- Putative polyketide synthase
- Gene
- rubA
- Organism
- Streptomyces achromogenes subsp. rubradiris
|
1uniprot[Pubmed] 9387157 [Medline] 98048398 Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997] | 2uniprot[Pubmed] 12889805 [Medline] 22771458 Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003] | [pubmed all]
|