| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q5SFB0_STRBI (Q5SFB0) |
|
|
0.0 |
2665 |
100% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGV
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
3
|
Q331Q2_9ACTO (Q331Q2) |
|
|
0.0 |
2358 |
89% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSV
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
14
|
Q52V44_9ACTO (Q52V44) |
|
(8 hsp) |
0.0 |
1042 |
58% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
16
|
D3Y1I5_9ACTO (D3Y1I5) |
|
(3 hsp) |
0.0 |
1038 |
59% |
|
- Product
- TamAIII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
17
|
F1DI33_9ACTO (F1DI33) |
|
(3 hsp) |
0.0 |
1038 |
59% |
|
- Product
- TrdAIII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
18
|
Q83WE6_MICGR (Q83WE6) |
|
(2 hsp) |
0.0 |
1037 |
58% |
|
- Product
- Protomycinolide IV synthase 5
- Gene
- mycAV
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
22
|
Q52V50_9ACTO (Q52V50) |
|
(8 hsp) |
0.0 |
1032 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
23
|
F2R780_STRVP (F2R780) |
|
|
0.0 |
1031 |
47% |
|
- Product
- Malonyl CoA-acyl carrier protein transacylase
- Gene
- SVEN_0485
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
27
|
D3Q135_STANL (D3Q135) |
|
|
0.0 |
1027 |
52% |
|
- Product
- 6-deoxyerythronolide-B synthase
- Gene
- Snas_4134
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
30
|
O30768_9ACTO (O30768) |
|
(2 hsp) |
0.0 |
1021 |
62% |
|
- Product
- Polyketide synthase module 7
- Gene
- nidA5
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
34
|
Q52V46_9ACTO (Q52V46) |
|
(11 hsp) |
0.0 |
1015 |
59% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
36
|
F1CLA9_9ACTO (F1CLA9) |
|
(12 hsp) |
0.0 |
1011 |
58% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
37
|
D7P612_CHOCO (D7P612) |
|
(2 hsp) |
0.0 |
1009 |
57% |
|
- Product
- TugB
- Gene
- tugB
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
38
|
B6ZK70_STRLS (B6ZK70) |
|
|
0.0 |
1009 |
48% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd17
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
42
|
D1GLV7_9ACTO (D1GLV7) |
|
(4 hsp) |
0.0 |
1008 |
60% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA3
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
52
|
Q49BD9_STRHY (Q49BD9) |
|
(4 hsp) |
0.0 |
996 |
55% |
|
- Product
- HbmAIII
- Gene
- hbmAIII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
53
|
D7P614_CHOCO (D7P614) |
|
(5 hsp) |
0.0 |
995 |
56% |
|
- Product
- TugD
- Gene
- tugD
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
57
|
Q84G22_STRHY (Q84G22) |
|
(4 hsp) |
0.0 |
993 |
55% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
58
|
Q52V53_9ACTO (Q52V53) |
|
(6 hsp) |
0.0 |
993 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
60
|
Q1L0T0_STRHY (Q1L0T0) |
|
(4 hsp) |
0.0 |
992 |
55% |
|
- Product
- GelC
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
61
|
F1CLC1_9ACTO (F1CLC1) |
|
(8 hsp) |
0.0 |
992 |
56% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
62
|
D7C2B8_STRBB (D7C2B8) |
|
(8 hsp) |
0.0 |
991 |
57% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
63
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(12 hsp) |
0.0 |
991 |
57% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
65
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(12 hsp) |
0.0 |
990 |
57% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
67
|
Q52V49_9ACTO (Q52V49) |
|
(4 hsp) |
0.0 |
989 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
68
|
D7P5Z3_SORCE (D7P5Z3) |
|
(9 hsp) |
0.0 |
988 |
57% |
|
- Product
- TgaA
- Gene
- tgaA
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
69
|
Q9X993_9ACTO (Q9X993) |
|
(8 hsp) |
0.0 |
988 |
57% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
70
|
Q93NW6_9ACTO (Q93NW6) |
|
(12 hsp) |
0.0 |
988 |
56% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
73
|
D7C2C2_STRBB (D7C2C2) |
|
(7 hsp) |
0.0 |
986 |
57% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-3
SBI_00655
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
74
|
Q70KH5_9ACTO (Q70KH5) |
|
(2 hsp) |
0.0 |
985 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
- aurB
- Organism
- Streptomyces thioluteus
|
1uniprot[Pubmed] 14700630 Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster.(Chem. Biol.) [2003] |
|
75
|
B2HPY9_MYCMM (B2HPY9) |
|
(2 hsp) |
0.0 |
985 |
45% |
|
- Product
- Polyketide synthase Pks6
- Gene
- pks6
MMAR_0707
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
76
|
Q93NX9_9ACTO (Q93NX9) |
|
(12 hsp) |
0.0 |
984 |
55% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
77
|
E4N2D1_KITSK (E4N2D1) |
|
|
0.0 |
982 |
46% |
|
- Product
- Putative modular polyketide synthase
- Gene
- pks2-3
KSE_65560
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
80
|
Q52V52_9ACTO (Q52V52) |
|
(6 hsp) |
0.0 |
981 |
58% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
82
|
F1CT53_9ACTO (F1CT53) |
|
(4 hsp) |
0.0 |
980 |
56% |
|
- Product
- GdmAIII
- Gene
- gdmAIII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
83
|
Q52V45_9ACTO (Q52V45) |
|
(4 hsp) |
0.0 |
980 |
54% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
85
|
D7BRE1_STRBB (D7BRE1) |
|
(7 hsp) |
0.0 |
979 |
56% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
86
|
Q30CS0_STRAU (Q30CS0) |
|
(4 hsp) |
0.0 |
979 |
55% |
|
- Product
- LipPks3
- Gene
- lipPks3
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
87
|
D7P613_CHOCO (D7P613) |
|
(4 hsp) |
0.0 |
979 |
55% |
|
- Product
- TugC
- Gene
- tugC
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
90
|
B6ZIR3_STRPT (B6ZIR3) |
|
(8 hsp) |
0.0 |
977 |
56% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
91
|
D7C2C3_STRBB (D7C2C3) |
|
(5 hsp) |
0.0 |
976 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
92
|
D7C2B7_STRBB (D7C2B7) |
|
(3 hsp) |
0.0 |
976 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-1
SBI_00650
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
93
|
A8L4B0_FRASN (A8L4B0) |
|
(4 hsp) |
0.0 |
976 |
58% |
|
- Product
- Beta-ketoacyl synthase
- Gene
- Franean1_3888
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
95
|
Q8KPW4_9ACTO (Q8KPW4) |
|
(2 hsp) |
0.0 |
975 |
57% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSII
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
96
|
Q30CR9_STRAU (Q30CR9) |
|
(4 hsp) |
0.0 |
975 |
55% |
|
- Product
- LipPks4
- Gene
- lipPks4
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
98
|
Q197Z2_9ACTO (Q197Z2) |
|
(4 hsp) |
0.0 |
974 |
56% |
|
- Product
- SalB
- Gene
-
- Organism
- Streptomyces albus
|
1uniprot[Pubmed] 18062184 Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.(Folia Microbiol. (Praha)) [2007] |
|
100
|
A0FCL3_STRVO (A0FCL3) |
|
(14 hsp) |
0.0 |
973 |
58% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|