| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
D6C455_9ACTO (D6C455) |
|
|
0.0 |
4533 |
100% |
|
- Product
- Modular polyketide synthase
- Gene
- pks1
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
2
|
D7C2H5_STRBB (D7C2H5) |
|
|
0.0 |
4199 |
98% |
|
- Product
- Modular polyketide synthase
- Gene
- pks4-2
SBI_00708
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
3
|
Q82QT4_STRAW (Q82QT4) |
|
(14 hsp) |
0.0 |
1592 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
5
|
Q93H87_STRAW (Q93H87) |
|
(11 hsp) |
0.0 |
1591 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
6
|
Q93HJ5_STRAW (Q93HJ5) |
|
(10 hsp) |
0.0 |
1481 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA1
SAV2899 SAV_2899
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
8
|
Q9ALM6_9PSEU (Q9ALM6) |
|
(3 hsp) |
0.0 |
1426 |
43% |
|
- Product
- Polyketide synthase loading and extender module 1
- Gene
- spnA
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
15
|
E0D202_9ACTO (E0D202) |
|
(9 hsp) |
0.0 |
1393 |
45% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
18
|
F1DI31_9ACTO (F1DI31) |
|
(8 hsp) |
0.0 |
1379 |
40% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
19
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(8 hsp) |
0.0 |
1376 |
41% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
20
|
D1GLV9_9ACTO (D1GLV9) |
|
(9 hsp) |
0.0 |
1375 |
41% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
21
|
Q93H84_STRAW (Q93H84) |
|
(8 hsp) |
0.0 |
1371 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA4
SAV416 SAV_416
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
23
|
Q9KIV4_STRAT (Q9KIV4) |
|
(4 hsp) |
0.0 |
1368 |
41% |
|
- Product
- 8,8a-deoxyoleandolide synthase 1
- Gene
- oleAI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
29
|
D7C2C2_STRBB (D7C2C2) |
|
(7 hsp) |
0.0 |
1346 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-3
SBI_00655
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
30
|
Q52V46_9ACTO (Q52V46) |
|
(12 hsp) |
0.0 |
1344 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
31
|
A0FCL1_STRVO (A0FCL1) |
|
(8 hsp) |
0.0 |
1343 |
41% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
32
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(14 hsp) |
0.0 |
1343 |
49% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
33
|
Q52V44_9ACTO (Q52V44) |
|
(10 hsp) |
0.0 |
1341 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
34
|
F1CLA9_9ACTO (F1CLA9) |
|
(14 hsp) |
0.0 |
1337 |
49% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
35
|
Q68BG5_STRHA (Q68BG5) |
|
(6 hsp) |
0.0 |
1318 |
41% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
36
|
Q1WEK7_9ACTO (Q1WEK7) |
|
(11 hsp) |
0.0 |
1314 |
49% |
|
- Product
- Polyketide synthase
- Gene
- merC
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
37
|
Q52V45_9ACTO (Q52V45) |
|
(5 hsp) |
0.0 |
1313 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
38
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(14 hsp) |
0.0 |
1310 |
51% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
39
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(11 hsp) |
0.0 |
1308 |
43% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
40
|
D6C473_9ACTO (D6C473) |
|
(9 hsp) |
0.0 |
1305 |
42% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA2
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
41
|
O30764_9ACTO (O30764) |
|
(9 hsp) |
0.0 |
1304 |
44% |
|
- Product
- Polyketide synthase modules 1 and 2
- Gene
- nidA1
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
43
|
Q93NX9_9ACTO (Q93NX9) |
|
(14 hsp) |
0.0 |
1302 |
49% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
45
|
Q9L4X3_9ACTO (Q9L4X3) |
|
(13 hsp) |
0.0 |
1299 |
49% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
46
|
D7C2C3_STRBB (D7C2C3) |
|
(7 hsp) |
0.0 |
1296 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
49
|
Q52V53_9ACTO (Q52V53) |
|
(9 hsp) |
0.0 |
1279 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
50
|
D7BRE1_STRBB (D7BRE1) |
|
(7 hsp) |
0.0 |
1278 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
51
|
A0FCL3_STRVO (A0FCL3) |
|
(16 hsp) |
0.0 |
1277 |
49% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
52
|
A0ACH3_STRAM (A0ACH3) |
|
(8 hsp) |
0.0 |
1276 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SAMR0467
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
53
|
Q27W58_STRVO (Q27W58) |
|
(6 hsp) |
0.0 |
1275 |
47% |
|
- Product
- NigAVII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
54
|
D8HZ82_AMYMU (D8HZ82) |
|
(6 hsp) |
0.0 |
1271 |
42% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifA
AMED_0617
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
55
|
O54666_AMYMD (O54666) |
|
(6 hsp) |
0.0 |
1271 |
42% |
|
- Product
- RifA
Rifamycin polyketide synthase, type 1
- Gene
- rifA
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
57
|
A8L4A9_FRASN (A8L4A9) |
|
(7 hsp) |
0.0 |
1267 |
48% |
|
- Product
- Erythronolide synthase
- Gene
- Franean1_3887
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
59
|
F1CLC1_9ACTO (F1CLC1) |
|
(12 hsp) |
0.0 |
1261 |
51% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
61
|
D7P614_CHOCO (D7P614) |
|
(8 hsp) |
0.0 |
1261 |
49% |
|
- Product
- TugD
- Gene
- tugD
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
63
|
Q9ALM3_9PSEU (Q9ALM3) |
|
(7 hsp) |
0.0 |
1250 |
48% |
|
- Product
- Polyketide synthase extender modules 5-7
- Gene
- spnD
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
65
|
E4N2C9_KITSK (E4N2C9) |
|
(3 hsp) |
0.0 |
1245 |
42% |
|
- Product
- Putative modular polyketide synthase
- Gene
- pks2-1
KSE_65540
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
66
|
C6WNU8_ACTMD (C6WNU8) |
|
(4 hsp) |
0.0 |
1245 |
47% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2682
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
67
|
B6ZIR2_STRPT (B6ZIR2) |
|
(12 hsp) |
0.0 |
1244 |
42% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
68
|
A4F5C5_SORCE (A4F5C5) |
|
(3 hsp) |
0.0 |
1242 |
50% |
|
- Product
- Polyketide synthase
- Gene
- spiF
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
69
|
E0D203_9ACTO (E0D203) |
|
(9 hsp) |
0.0 |
1241 |
48% |
|
- Product
- Polyketide synthase
- Gene
- gfsB
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
70
|
Q93H83_STRAW (Q93H83) |
|
(4 hsp) |
0.0 |
1239 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA5
SAV415 SAV_415
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
72
|
D2CKL5_PSEAH (D2CKL5) |
|
(13 hsp) |
0.0 |
1239 |
48% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
73
|
D7C2B8_STRBB (D7C2B8) |
|
(11 hsp) |
0.0 |
1237 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
74
|
D7P5Z5_SORCE (D7P5Z5) |
|
(8 hsp) |
0.0 |
1236 |
49% |
|
- Product
- TgaC
- Gene
- tgaC
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
75
|
D7C2J3_STRBB (D7C2J3) |
|
(10 hsp) |
0.0 |
1235 |
40% |
|
- Product
- Type I polyketide synthase
- Gene
- milA2
SBI_00726
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
76
|
A0ACH1_STRAM (A0ACH1) |
|
(11 hsp) |
0.0 |
1234 |
49% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0465
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
78
|
D7P613_CHOCO (D7P613) |
|
(6 hsp) |
0.0 |
1229 |
49% |
|
- Product
- TugC
- Gene
- tugC
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
82
|
C0SMW4_9ACTO (C0SMW4) |
|
(17 hsp) |
0.0 |
1225 |
47% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
83
|
Q9X993_9ACTO (Q9X993) |
|
(12 hsp) |
0.0 |
1224 |
50% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
86
|
D7BRD7_STRBB (D7BRD7) |
|
(4 hsp) |
0.0 |
1216 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01979
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
87
|
D3U9Y6_9ACTO (D3U9Y6) |
|
(6 hsp) |
0.0 |
1216 |
50% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaF
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
88
|
Q68BG4_STRHA (Q68BG4) |
|
(11 hsp) |
0.0 |
1213 |
48% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
89
|
A1YBT8_SORCE (A1YBT8) |
|
(4 hsp) |
0.0 |
1212 |
49% |
|
- Product
- JerE
- Gene
- jerE
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17185223 Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.(Chem. Biol.) [2006] |
|
90
|
Q52V51_9ACTO (Q52V51) |
|
(4 hsp) |
0.0 |
1211 |
46% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
91
|
Q70I01_9ACTO (Q70I01) |
|
(3 hsp) |
0.0 |
1208 |
50% |
|
- Product
- Borrelidin polyketide synthase, type I
- Gene
- borA2
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
92
|
Q9L4X2_9ACTO (Q9L4X2) |
|
(9 hsp) |
0.0 |
1207 |
49% |
|
- Product
- NysJ
- Gene
- nysJ
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
95
|
Q53840_SORCE (Q53840) |
|
(14 hsp) |
0.0 |
1204 |
49% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
97
|
B1W4J2_STRGG (B1W4J2) |
|
(7 hsp) |
0.0 |
1201 |
46% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-2
SGR_6180
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
98
|
C0SMW3_9ACTO (C0SMW3) |
|
(8 hsp) |
0.0 |
1199 |
46% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmI
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|