| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
D6C473_9ACTO (D6C473) |
|
|
0.0 |
12000 |
100% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA2
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
2
|
Q9S0R7_STRAW (Q9S0R7) |
|
|
0.0 |
6114 |
58% |
|
- Product
- Type I polyketide synthase AVES 2
- Gene
- aveA2
SAV939 SAV_939
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 10449723 [Medline] 99380548 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999] | 2uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 3uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
4
|
F1DI31_9ACTO (F1DI31) |
|
(9 hsp) |
0.0 |
5039 |
49% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
5
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(9 hsp) |
0.0 |
5037 |
49% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
6
|
D1GLV9_9ACTO (D1GLV9) |
|
(7 hsp) |
0.0 |
4726 |
46% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
9
|
D7C2J3_STRBB (D7C2J3) |
|
(20 hsp) |
0.0 |
4323 |
77% |
|
- Product
- Type I polyketide synthase
- Gene
- milA2
SBI_00726
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
11
|
Q52V46_9ACTO (Q52V46) |
|
(12 hsp) |
0.0 |
4165 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
12
|
Q52V44_9ACTO (Q52V44) |
|
(15 hsp) |
0.0 |
4130 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
13
|
C9YYI3_STRSW (C9YYI3) |
|
(8 hsp) |
0.0 |
4086 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
14
|
Q3S869_9ACTO (Q3S869) |
|
(8 hsp) |
0.0 |
4065 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
15
|
E0D202_9ACTO (E0D202) |
|
(11 hsp) |
0.0 |
4013 |
47% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
18
|
D6C474_9ACTO (D6C474) |
|
(11 hsp) |
0.0 |
3915 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA4
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
20
|
C9YYI1_STRSW (C9YYI1) |
|
(7 hsp) |
0.0 |
3820 |
47% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
21
|
B6CLY1_9MYCO (B6CLY1) |
|
(24 hsp) |
0.0 |
3710 |
45% |
|
- Product
- Type I modular polyketide synthase, MlsB
- Gene
- mlsB
MULP_051
- Organism
- Mycobacterium liflandii 128FXT
|
1uniprot[Pubmed] 18840298 Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008] |
|
22
|
A0FCL3_STRVO (A0FCL3) |
|
(25 hsp) |
0.0 |
3651 |
46% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
23
|
Q93H84_STRAW (Q93H84) |
|
(13 hsp) |
0.0 |
3640 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA4
SAV416 SAV_416
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
27
|
Q27W58_STRVO (Q27W58) |
|
(10 hsp) |
0.0 |
3576 |
51% |
|
- Product
- NigAVII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
28
|
D7BRE1_STRBB (D7BRE1) |
|
(12 hsp) |
0.0 |
3524 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
29
|
B1W4J2_STRGG (B1W4J2) |
|
(14 hsp) |
0.0 |
3513 |
46% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-2
SGR_6180
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
30
|
D7C2C2_STRBB (D7C2C2) |
|
(11 hsp) |
0.0 |
3423 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-3
SBI_00655
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
31
|
Q1WEK7_9ACTO (Q1WEK7) |
|
(17 hsp) |
0.0 |
3387 |
49% |
|
- Product
- Polyketide synthase
- Gene
- merC
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
32
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(20 hsp) |
0.0 |
3373 |
48% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
34
|
F1CLA9_9ACTO (F1CLA9) |
|
(22 hsp) |
0.0 |
3363 |
48% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
35
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(22 hsp) |
0.0 |
3353 |
49% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
37
|
Q93HJ4_STRAW (Q93HJ4) |
|
(7 hsp) |
0.0 |
3276 |
43% |
|
- Product
- Modular polyketide synthase
OlmA2 protein
- Gene
- olmA2
SAV2898 SAV_2898
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
38
|
Q93NX9_9ACTO (Q93NX9) |
|
(23 hsp) |
0.0 |
3273 |
47% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
39
|
E4NJF1_KITSK (E4NJF1) |
|
(11 hsp) |
0.0 |
3241 |
45% |
|
- Product
- Modular polyketide synthase BFAS1
- Gene
- bfmA1
KSE_73440
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
40
|
Q9L4X3_9ACTO (Q9L4X3) |
|
(22 hsp) |
0.0 |
3239 |
47% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
41
|
A0ACH1_STRAM (A0ACH1) |
|
(20 hsp) |
0.0 |
3211 |
47% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0465
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
42
|
Q3S865_9ACTO (Q3S865) |
|
(11 hsp) |
0.0 |
3199 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
43
|
C9YYI0_STRSW (C9YYI0) |
|
(11 hsp) |
0.0 |
3189 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83891
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
44
|
Q93HJ2_STRAW (Q93HJ2) |
|
(12 hsp) |
0.0 |
3167 |
46% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA6
SAV2896 SAV_2896
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
46
|
A4F5C7_SORCE (A4F5C7) |
|
(7 hsp) |
0.0 |
3162 |
42% |
|
- Product
- Polyketide synthase
- Gene
- spiH
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
49
|
D2CKL5_PSEAH (D2CKL5) |
|
(20 hsp) |
0.0 |
3128 |
46% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
52
|
B6ZIR3_STRPT (B6ZIR3) |
|
(14 hsp) |
0.0 |
3020 |
46% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
53
|
Q82QT4_STRAW (Q82QT4) |
|
(16 hsp) |
0.0 |
3011 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
54
|
Q93H87_STRAW (Q93H87) |
|
(12 hsp) |
0.0 |
3011 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
55
|
A0ACI0_STRAM (A0ACI0) |
|
(17 hsp) |
0.0 |
2975 |
46% |
|
- Product
- Putative modular polyketide synthase
- Gene
- SAMR0474
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
57
|
E0D203_9ACTO (E0D203) |
|
(12 hsp) |
0.0 |
2937 |
47% |
|
- Product
- Polyketide synthase
- Gene
- gfsB
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
58
|
Q9KIV4_STRAT (Q9KIV4) |
|
(9 hsp) |
0.0 |
2890 |
43% |
|
- Product
- 8,8a-deoxyoleandolide synthase 1
- Gene
- oleAI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
59
|
F1DI32_9ACTO (F1DI32) |
|
(8 hsp) |
0.0 |
2867 |
48% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
60
|
Q68BG4_STRHA (Q68BG4) |
|
(18 hsp) |
0.0 |
2845 |
49% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
61
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(8 hsp) |
0.0 |
2831 |
48% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
62
|
Q52V53_9ACTO (Q52V53) |
|
(11 hsp) |
0.0 |
2799 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
63
|
A0ACI3_STRAM (A0ACI3) |
|
(10 hsp) |
0.0 |
2798 |
46% |
|
- Product
- Putative type I modular polyketide synthase
- Gene
- SAMR0477
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
64
|
C0SMW4_9ACTO (C0SMW4) |
|
(27 hsp) |
0.0 |
2777 |
45% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
65
|
Q68BG5_STRHA (Q68BG5) |
|
(11 hsp) |
0.0 |
2774 |
46% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
66
|
B1W485_STRGG (B1W485) |
|
(11 hsp) |
0.0 |
2746 |
45% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
68
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(12 hsp) |
0.0 |
2734 |
49% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
69
|
A0FCL1_STRVO (A0FCL1) |
|
(12 hsp) |
0.0 |
2733 |
48% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
70
|
F1CLC1_9ACTO (F1CLC1) |
|
(17 hsp) |
0.0 |
2728 |
48% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
71
|
B6ZIR2_STRPT (B6ZIR2) |
|
(13 hsp) |
0.0 |
2720 |
47% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
72
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(17 hsp) |
0.0 |
2716 |
46% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
73
|
D6C4C5_9ACTO (D6C4C5) |
|
(12 hsp) |
0.0 |
2706 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA1
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
74
|
D7C488_STRBB (D7C488) |
|
(12 hsp) |
0.0 |
2701 |
51% |
|
- Product
- Type I polyketide synthase
- Gene
- milA1
SBI_00789
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
75
|
D7BSM1_STRBB (D7BSM1) |
|
(7 hsp) |
0.0 |
2700 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
77
|
B6CLY8_9MYCO (B6CLY8) |
|
(37 hsp) |
0.0 |
2692 |
45% |
|
- Product
- Type I modular polyketide synthase, MlsA1
- Gene
- mlsA1
MULP_065
- Organism
- Mycobacterium liflandii 128FXT
|
1uniprot[Pubmed] 18840298 Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008] |
|
78
|
E2Q518_STRCL (E2Q518) |
|
(7 hsp) |
0.0 |
2687 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0012
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
80
|
Q7WTD6_9ACTO (Q7WTD6) |
|
(8 hsp) |
0.0 |
2685 |
47% |
|
- Product
- NanA8
- Gene
- nanA8
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
81
|
Q9X993_9ACTO (Q9X993) |
|
(17 hsp) |
0.0 |
2670 |
48% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
82
|
D3U9Y8_9ACTO (D3U9Y8) |
|
(18 hsp) |
0.0 |
2667 |
46% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaH
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
83
|
A4KCE4_9ACTO (A4KCE4) |
|
(26 hsp) |
0.0 |
2665 |
45% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] |
|
85
|
C6ZCS1_9ACTO (C6ZCS1) |
|
(26 hsp) |
0.0 |
2663 |
45% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnA
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
86
|
Q9L4X2_9ACTO (Q9L4X2) |
|
(10 hsp) |
0.0 |
2651 |
46% |
|
- Product
- NysJ
- Gene
- nysJ
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
89
|
E4NJF4_KITSK (E4NJF4) |
|
(8 hsp) |
0.0 |
2636 |
48% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
90
|
C0SMW3_9ACTO (C0SMW3) |
|
(16 hsp) |
0.0 |
2634 |
46% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmI
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
91
|
Q93HJ5_STRAW (Q93HJ5) |
|
(17 hsp) |
0.0 |
2633 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA1
SAV2899 SAV_2899
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
93
|
B1W4J5_STRGG (B1W4J5) |
|
(9 hsp) |
0.0 |
2630 |
48% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-5
SGR_6183
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
94
|
Q9ALM3_9PSEU (Q9ALM3) |
|
(11 hsp) |
0.0 |
2625 |
48% |
|
- Product
- Polyketide synthase extender modules 5-7
- Gene
- spnD
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
96
|
B2HNF5_MYCMM (B2HNF5) |
|
(10 hsp) |
0.0 |
2620 |
43% |
|
- Product
- Type I modular polyketide synthase
- Gene
- MMAR_3798
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
98
|
Q68BG3_STRHA (Q68BG3) |
|
(8 hsp) |
0.0 |
2610 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsC
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
100
|
Q8KPW5_9ACTO (Q8KPW5) |
|
(9 hsp) |
0.0 |
2607 |
46% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSI
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|