Alanine racemization(NFUNC_0063) |
必須 | A | ALR (NRULE_0228) | Alanine racemase | EH105704_21_00080 EH105704_28_00050 |
Ampicillin resistance(NFUNC_0046) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | EH105704_10_00980 |
Anthranilate biosynthesis(NFUNC_0038) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | EH105704_12_00100 EH105704_07_00260 |
TRPE (NRULE_0143) | Anthranilate synthase component I | EH105704_12_00110 |
Aromatic azo compounds degradation(NFUNC_0073) |
必須 | A | AZOR (NRULE_0236) | FMN-dependent NADH-azoreductase | EH105704_12_00760 |
Arsenical resistance(NFUNC_0004) |
必須 | A | ARSB1 (NRULE_0015) | Arsenical pump membrane protein | EH105704_06_01410 EH105704_33_00040 |
ARSC1 (NRULE_0017) | Arsenate reductase | EH105704_06_01400 EH105704_01_08790 EH105704_33_00030 |
任意 | | ARSA (NRULE_0014) | Arsenical pump-driving ATPase | EH105704_33_00050 |
| ARSD (NRULE_0020) | Arsenical resistance operon trans-acting repressor ArsD | EH105704_33_00060 |
Bacitracin resistance(NFUNC_0022) |
必須 | A | UPPP (NRULE_0097) | Undecaprenyl-diphosphatase | EH105704_19_00120 |
Beta-lactam antibiotic resistance(NFUNC_0033) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | EH105704_10_00980 |
Biotin biosynthesis(NFUNC_0051) |
必須 | A | BIOF (NRULE_0182) | 8-amino-7-oxononanoate synthase | EH105704_23_00130 |
BIOA (NRULE_0183) | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | EH105704_23_00150 |
BIOD (NRULE_0184) | ATP-dependent dethiobiotin synthetase BioD | EH105704_23_00110 EH105704_05_02150 |
BIOB (NRULE_0185) | Biotin synthase | EH105704_23_00140 |
Chloramphenicol resistance(NFUNC_0025) |
必須 | A | CAT1 (NRULE_0107) | Chloramphenicol acetyltransferase | EH105704_16_00330 |
Folate biosynthesis(NFUNC_0044) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | EH105704_12_00100 EH105704_07_00260 |
DHPS (NRULE_0144) | Dihydropteroate synthase | EH105704_02_01930 |
FOLM (NRULE_0146) | Dihydrofolate reductase FolM | EH105704_05_00380 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | EH105704_01_07480 EH105704_19_00110 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | EH105704_09_00550 |
FOLC (NRULE_0160) | Bifunctional protein FolC | EH105704_01_07590 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | EH105704_01_03030 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | EH105704_03_02500 |
B | GLAT (NRULE_0142) | Glutamine amidotransferase | EH105704_07_00260 EH105704_12_00100 |
DHPS (NRULE_0144) | Dihydropteroate synthase | EH105704_02_01930 |
FOLA (NRULE_0147) | Dihydrofolate reductase | EH105704_02_03010 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | EH105704_01_07480 EH105704_19_00110 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | EH105704_09_00550 |
FOLC (NRULE_0160) | Bifunctional protein FolC | EH105704_01_07590 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | EH105704_01_03030 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | EH105704_03_02500 |
Macrolide antibiotic resistance(NFUNC_0045) |
必須 | B | RLMA (NRULE_0165) | 23S rRNA (guanine-N(1))-methyltransferase | EH105704_01_03140 |
C | MACA (NRULE_0166) | Macrolide-specific efflux protein MacA | EH105704_01_04950 |
MACB (NRULE_0167) | Macrolide export ATP-binding/permease protein MacB | EH105704_01_06920 EH105704_01_04940 |
Metal-binding protein(NFUNC_0105) |
必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | EH105704_23_00250 EH105704_23_00290 |
B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | EH105704_23_00290 |
C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | EH105704_23_00270 EH105704_21_00250 EH105704_20_00440 EH105704_08_01110 EH105704_01_08330 |
E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | EH105704_29_00210 |
F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | EH105704_02_00080 |
G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR | EH105704_27_00130 |
H | NIKR (NRULE_0331) | Nickel-responsive transcriptional regulator NikR | EH105704_06_01910 |
I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | EH105704_01_09190 |
Molybdate transport (ABC transporter)(NFUNC_0097) |
必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | EH105704_21_00250 EH105704_01_08330 EH105704_20_00440 EH105704_08_01110 EH105704_23_00270 |
任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | EH105704_23_00290 |
| MODB (NRULE_0325) | Molybdate ABC transporter permease protein | EH105704_23_00260 |
| MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | EH105704_23_00250 |
(R)-pantothenate biosynthesis(NFUNC_0030) |
必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | EH105704_09_00510 |
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | EH105704_09_00540 |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | EH105704_01_09730 EH105704_02_04370 |
PANC (NRULE_0118) | Pantothenate synthetase | EH105704_09_00520 |
Penicillin resistance(NFUNC_0047) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | EH105704_10_00980 |
Riboflavin biosynthesis(NFUNC_0058) |
必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | EH105704_19_00190 |
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | EH105704_12_00230 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | EH105704_10_00130 |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | EH105704_10_00120 |
RIBE (NRULE_0204) | Riboflavin synthase | EH105704_01_00320 |
任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | EH105704_02_02700 |
Trehalose biosynthesis (from maltooligosaccharide)(NFUNC_0037) |
必須 | A | TREY (NRULE_0140) | Maltooligosyl trehalose synthase | EH105704_10_00890 |
TREZ (NRULE_0141) | Malto-oligosyltrehalose trehalohydrolase | EH105704_10_00900 |
任意 | | GLGX (NRULE_0139) | Glycogen debranching enzyme | EH105704_10_00880 EH105704_07_00840 |
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031) |
必須 | A | TPS (NRULE_0119) | Trehalose-phosphate synthase | EH105704_01_03970 |
TPP (NRULE_0120) | Trehalose-6-phosphate phosphatase | EH105704_01_03980 |
Uptake of osmoprotectant(NFUNC_0061) |
必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | EH105704_15_00130 |
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | EH105704_15_00140 |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | EH105704_15_00150 EH105704_05_01020 |
C | BCCT (NRULE_0220) | BCCT family transporter | EH105704_06_01920 |
D | PROP (NRULE_0221) | Osmoprotectant transporter | EH105704_12_00830 |
E | OPUE (NRULE_0222) | Sodium/proline symporter | EH105704_01_04060 |
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) |
必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase | EH105704_02_03810 |
PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase | EH105704_01_07640 |
SERC (NRULE_0210) | Phosphoserine aminotransferase | EH105704_01_04740 |
PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | EH105704_02_03050 EH105704_09_00370 |
PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | EH105704_18_00390 |