| ID |
NRULE_0128 |
| Rule name |
TRES |
| Created |
2013-02-06 |
| Protein name |
Protein name
- Full
- Trehalose synthase
- EC
- EC 5.4.99.16
Synonym
- Full
- Maltose alpha-D-glucosyltransferase
|
| Gene name |
treS |
| Rule Trigger |
TIGRFAMs; TIGR02456; hit=1 |
| Cross Reference |
Gene Ontology
- GO
- GO:0047471, F:maltose alpha-D-glucosyltransferase activity, IEA:EC
- GO:0046872, F:metal ion binding, IEA:UniProtKB-KW
- GO:0005975, P:carbohydrate metabolic process, IEA:InterPro
Family and domain databases
- InterPro
- IPR006047, Glyco_hydro_13_cat_dom
- IPR006589, Glyco_hydro_13_sub_cat_dom
- IPR012810, TreS/a-amylase_N
- Pfam
- PF00128, Alpha-amylase, 1
- SMART
- SM00642, Aamy, 1
- TIGRFAMs
- TIGR02456, treS_nterm, 1
|
| Feature |
P72235 Pimelobacter sp. (strain R48).
| CHAIN | 1 - 573 | Trehalose synthase. /FTId=PRO_0000054343. |
| ACT_SITE | 210 | Nucleophile (By similarity). |
| ACT_SITE | 252 | Proton donor (By similarity). |
| METAL | 112 | Calcium (By similarity). |
| METAL | 180 | Calcium (By similarity). |
| METAL | 214 | Calcium; via carbonyl oxygen (By similarity). |
|
| General annotation |
- Function
- Catalyzes the reversible interconversion of maltose and alpha,alpha-trehalose by transglucosylation (By similarity). TreS from Mycobacterium smegmatis and M. tuberculosis have amylase activity in addition to the trehalose synthase activity
- Catalytic activity
- Maltose = alpha,alpha-trehalose
- Sequence similarities
- Belongs to the glycosyl hydrolase 13 family. TreS subfamily
|
| Reference |
- P72235 Pimelobacter sp. (strain R48).
- 8645698
- Cloning and sequencing of trehalose synthase gene from Pimelobacter sp. R48. (Biochim Biophys Acta. 1996)
- A0R6E0 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155).
- 18505459
- Trehalose synthase converts glycogen to trehalose. (FEBS J. 2008)
|
