| ID |
NRULE_0233 |
| 遺伝子ID |
MLE |
| 作成日 |
2013/07/23 |
| タンパク質名 |
Protein name
- Full
- Malolactic enzyme
|
| 遺伝子名 |
該当データなし |
| 遺伝子条件 |
BLASTP; Q48796; hit=1; score=1500; pid=50 |
| 参照 |
Gene Ontology
- GO
- GO:0016619, F:malate dehydrogenase (oxaloacetate-decarboxylating) activity, IEA:InterPro
- GO:0046872, F:metal ion binding, IEA:UniProtKB-KW
- GO:0051287, F:NAD binding, IEA:InterPro
- GO:0006108, P:malate metabolic process, IEA:InterPro
Family and domain databases
- InterPro
- IPR015884, Malic_enzyme_CS
- IPR012301, Malic_N
- IPR012302, Malic_NAD-bd
- IPR001891, Malic_OxRdtase
- Pfam
- PF00390, malic, 1
- PF03949, Malic_M, 1
- PIRSF
- PIRSF000106, ME, 1
- PRINTS
- PR00072, MALOXRDTASE
- SMART
- SM00919, Malic_M, 1
- PROSITE
- PS00331, MALIC_ENZYMES;
|
| 配列の特徴 |
Q48796 Oenococcus oeni (Leuconostoc oenos).
| ACT_SITE | 91 | Proton donor (By similarity). |
| ACT_SITE | 164 | Proton acceptor (By similarity). |
| METAL | 235 | Divalent metal cation (By similarity). |
| METAL | 236 | Divalent metal cation (By similarity). |
| METAL | 259 | Divalent metal cation (By similarity). |
| BINDING | 259 | NAD (By similarity). |
| BINDING | 404 | NAD (By similarity). |
|
| 注釈 |
- Function
- Key enzyme in the degradation of L-malic acid by lactic acid bacteria
- Catalytic activity
- (S)-malate + NAD(+) = lactate + CO(2) + NADH
- Cofactor
- Divalent metal cations. Prefers magnesium or manganese (By similarity)
- Sequence similarities
- Belongs to the malic enzymes family
|
| 参考文献 |
- Q48796 Oenococcus oeni (Leuconostoc oenos).
- 8919788
- Cloning and characterization of the genes encoding the malolactic enzyme and the malate permease of Leuconostoc oenos. (Appl Environ Microbiol. 1996)
- Q48662 Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
- 8132158
- Cloning and sequence analysis of the gene encoding Lactococcus lactis malolactic enzyme: relationships with malic enzymes. (FEMS Microbiol Lett. 1994)
|
