| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
O30767_9ACTO (O30767) |
|
|
0.0 |
3116 |
100% |
|
- Product
- Polyketide synthase module 6
- Gene
- nidA4
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
2
|
O30768_9ACTO (O30768) |
|
|
0.0 |
1547 |
63% |
|
- Product
- Polyketide synthase module 7
- Gene
- nidA5
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
3
|
Q5SFB1_STRBI (Q5SFB1) |
|
|
0.0 |
1308 |
50% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGIV
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
5
|
Q331Q3_9ACTO (Q331Q3) |
|
|
0.0 |
1290 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSIV
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
8
|
Q9ZGI3_9ACTO (Q9ZGI3) |
|
|
0.0 |
1285 |
50% |
|
- Product
- Type I polyketide synthase PikAIII
- Gene
- pikAIII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] | 2uniprot[Pubmed] 19146481 Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.(ACS Chem. Biol.) [2009] | [pubmed all]
|
9
|
Q3S864_9ACTO (Q3S864) |
|
(4 hsp) |
0.0 |
1281 |
49% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
12
|
C9YYI1_STRSW (C9YYI1) |
|
(4 hsp) |
0.0 |
1267 |
50% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
14
|
Q52V51_9ACTO (Q52V51) |
|
(2 hsp) |
0.0 |
1262 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
15
|
E4NJF2_KITSK (E4NJF2) |
|
(4 hsp) |
0.0 |
1258 |
51% |
|
- Product
- Modular polyketide synthase BFAS2
- Gene
- bfmA2
KSE_73450
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
17
|
D7CC08_STRBB (D7CC08) |
|
(5 hsp) |
0.0 |
1254 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
19
|
Q93HJ1_STRAW (Q93HJ1) |
|
(3 hsp) |
0.0 |
1248 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA7
SAV2895 SAV_2895
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
20
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(6 hsp) |
0.0 |
1247 |
49% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
22
|
A0FCL1_STRVO (A0FCL1) |
|
(6 hsp) |
0.0 |
1245 |
49% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
23
|
Q93H83_STRAW (Q93H83) |
|
(2 hsp) |
0.0 |
1241 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA5
SAV415 SAV_415
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
26
|
E0D202_9ACTO (E0D202) |
|
(7 hsp) |
0.0 |
1239 |
49% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
28
|
B1W487_STRGG (B1W487) |
|
(2 hsp) |
0.0 |
1235 |
49% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-3
SGR_6075
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
29
|
Q68BG5_STRHA (Q68BG5) |
|
(4 hsp) |
0.0 |
1234 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
30
|
E9LIP5_9ACTO (E9LIP5) |
|
(3 hsp) |
0.0 |
1233 |
48% |
|
- Product
- Putative modular polyketide synthase
- Gene
- tiaA2
- Organism
- Dactylosporangium aurantiacum subsp. hamdenensis
|
1uniprot[Pubmed] 21186805 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011] |
|
35
|
B1W488_STRGG (B1W488) |
|
|
0.0 |
1220 |
47% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-4
SGR_6076
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
36
|
Q52V47_9ACTO (Q52V47) |
|
|
0.0 |
1219 |
47% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
37
|
Q5SFB4_STRBI (Q5SFB4) |
|
(5 hsp) |
0.0 |
1216 |
48% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGI
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
38
|
Q3S869_9ACTO (Q3S869) |
|
(4 hsp) |
0.0 |
1214 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
40
|
D7BRE1_STRBB (D7BRE1) |
|
(4 hsp) |
0.0 |
1214 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
41
|
Q8KPW5_9ACTO (Q8KPW5) |
|
(5 hsp) |
0.0 |
1211 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSI
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
42
|
A4FH85_SACEN (A4FH85) |
|
(5 hsp) |
0.0 |
1211 |
47% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
43
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(5 hsp) |
0.0 |
1211 |
47% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
44
|
Q0QMN7_9ACTO (Q0QMN7) |
|
(4 hsp) |
0.0 |
1210 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces sp. Eco86
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
45
|
B6ZIR3_STRPT (B6ZIR3) |
|
(7 hsp) |
0.0 |
1210 |
47% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
50
|
C9YYI3_STRSW (C9YYI3) |
|
(4 hsp) |
0.0 |
1203 |
46% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
51
|
Q9ALM4_9PSEU (Q9ALM4) |
|
(2 hsp) |
0.0 |
1202 |
47% |
|
- Product
- Polyketide synthase extender modules 3-4
- Gene
- spnC
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
52
|
Q93NX9_9ACTO (Q93NX9) |
|
(7 hsp) |
0.0 |
1202 |
47% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
53
|
D2CKL5_PSEAH (D2CKL5) |
|
(7 hsp) |
0.0 |
1201 |
48% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
55
|
A4FH83_SACEN (A4FH83) |
|
(5 hsp) |
0.0 |
1197 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
56
|
Q5VKR4_SACER (Q5VKR4) |
|
(5 hsp) |
0.0 |
1197 |
48% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
57
|
D3U9Y9_9ACTO (D3U9Y9) |
|
(3 hsp) |
0.0 |
1194 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaI
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
58
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(7 hsp) |
0.0 |
1193 |
47% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
59
|
F1DI31_9ACTO (F1DI31) |
|
(6 hsp) |
0.0 |
1192 |
47% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
62
|
B1W490_STRGG (B1W490) |
|
(2 hsp) |
0.0 |
1189 |
47% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-6
SGR_6078
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
63
|
A4F7N8_SACEN (A4F7N8) |
|
(3 hsp) |
0.0 |
1187 |
47% |
|
- Product
- EryAI Erythromycin polyketide synthase modules 1 and 2
- Gene
- eryAI
SACE_0721
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
64
|
Q5UNP6_SACER (Q5UNP6) |
|
(3 hsp) |
0.0 |
1187 |
47% |
|
- Product
- EryAI
- Gene
- eryAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
65
|
C5HV16_STRAT (C5HV16) |
|
(5 hsp) |
0.0 |
1186 |
47% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
66
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(6 hsp) |
0.0 |
1186 |
47% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
69
|
ERYA1_SACER (Q03131) |
|
(3 hsp) |
0.0 |
1184 |
47% |
|
- Product
- Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I DEBS 1 ORF 1
- Gene
- eryA
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 2024119 [Medline] 91220065 Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991] | 2uniprot[Pubmed] 8386127 [Medline] 93231529 IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea.(Gene) [1993] | [pubmed all]
|
72
|
A4F7P1_SACEN (A4F7P1) |
|
(2 hsp) |
0.0 |
1179 |
48% |
|
- Product
- EryAIII Erythromycin polyketide synthase modules 5 and 6
- Gene
- eryAIII
SACE_0724
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
73
|
Q5UNP4_SACER (Q5UNP4) |
|
(2 hsp) |
0.0 |
1179 |
48% |
|
- Product
- EryAIII
- Gene
- eryAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] | 2uniprot[Pubmed] 16844787 The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.(Proc. Natl. Acad. Sci. U.S.A.) [2006] | [pubmed all]
|
74
|
Q68BG3_STRHA (Q68BG3) |
|
(3 hsp) |
0.0 |
1179 |
45% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsC
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
75
|
A0FCL2_STRVO (A0FCL2) |
|
(7 hsp) |
0.0 |
1178 |
46% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
76
|
E2Q520_STRCL (E2Q520) |
|
(5 hsp) |
0.0 |
1178 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0014
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
78
|
Q93NW7_9ACTO (Q93NW7) |
|
(2 hsp) |
0.0 |
1177 |
45% |
|
- Product
- AmphB
- Gene
- amphB
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | 3uniprot[Pubmed] 20696392 Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010] | [pubmed all]
|
79
|
Q84G23_STRHY (Q84G23) |
|
(3 hsp) |
0.0 |
1176 |
47% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
80
|
Q49BE0_STRHY (Q49BE0) |
|
(3 hsp) |
0.0 |
1175 |
47% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
81
|
D7P5Z4_SORCE (D7P5Z4) |
|
(3 hsp) |
0.0 |
1174 |
47% |
|
- Product
- TgaB
- Gene
- tgaB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
82
|
Q1L0T1_STRHY (Q1L0T1) |
|
(3 hsp) |
0.0 |
1172 |
47% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
83
|
D7C488_STRBB (D7C488) |
|
(5 hsp) |
0.0 |
1171 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- milA1
SBI_00789
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
86
|
D1GLV8_9ACTO (D1GLV8) |
|
(3 hsp) |
0.0 |
1169 |
45% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
89
|
E4NJF4_KITSK (E4NJF4) |
|
(3 hsp) |
0.0 |
1166 |
47% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
90
|
B1W485_STRGG (B1W485) |
|
(5 hsp) |
0.0 |
1166 |
48% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
91
|
Q30CS2_STRAU (Q30CS2) |
|
(3 hsp) |
0.0 |
1166 |
47% |
|
- Product
- LipPks1
- Gene
- lipPks1
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
92
|
B6ZIR4_STRPT (B6ZIR4) |
|
(3 hsp) |
0.0 |
1166 |
48% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
93
|
Q9L4X3_9ACTO (Q9L4X3) |
|
(7 hsp) |
0.0 |
1165 |
47% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
94
|
Q6W5P9_9ACTO (Q6W5P9) |
|
(5 hsp) |
0.0 |
1165 |
45% |
|
- Product
- FscB
- Gene
- fscB
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
95
|
Q9L4W4_9ACTO (Q9L4W4) |
|
(2 hsp) |
0.0 |
1165 |
45% |
|
- Product
- NysB
- Gene
- nysB
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
96
|
Q9ZGI5_9ACTO (Q9ZGI5) |
|
(4 hsp) |
0.0 |
1163 |
48% |
|
- Product
- Type I polyketide synthase PikAI
- Gene
- pikAI
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
97
|
B6ZIR2_STRPT (B6ZIR2) |
|
(7 hsp) |
0.0 |
1163 |
48% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
98
|
OL56_STRAT (Q07017) |
|
(2 hsp) |
0.0 |
1162 |
46% |
|
- Product
- Oleandomycin polyketide synthase, modules 5 and 6
- Gene
- orfB
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 8107683 [Medline] 94150470 Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence.(Mol. Gen. Genet.) [1994] |
|
99
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(7 hsp) |
0.0 |
1162 |
45% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
100
|
A4FH82_SACEN (A4FH82) |
|
|
0.0 |
1161 |
45% |
|
- Product
- Type I PKS modular polyketide synthas
- Gene
- SACE_4138
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|