| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
C5HV14_STRAT (C5HV14) |
|
|
0.0 |
9350 |
100% |
|
- Product
- Polyketide synthase
- Gene
- idmL
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
3
|
A0FCL3_STRVO (A0FCL3) |
|
(23 hsp) |
0.0 |
3123 |
50% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
4
|
A0ACH1_STRAM (A0ACH1) |
|
(15 hsp) |
0.0 |
3110 |
53% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0465
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
5
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(14 hsp) |
0.0 |
3075 |
50% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
6
|
A0FCL2_STRVO (A0FCL2) |
|
(14 hsp) |
0.0 |
3061 |
49% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
7
|
Q53840_SORCE (Q53840) |
|
(15 hsp) |
0.0 |
3058 |
50% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
12
|
A4F5C6_SORCE (A4F5C6) |
|
(9 hsp) |
0.0 |
3007 |
50% |
|
- Product
- Polyketide synthase
- Gene
- spiG
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
13
|
C0SMW3_9ACTO (C0SMW3) |
|
(7 hsp) |
0.0 |
2991 |
49% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmI
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
14
|
D7C2B8_STRBB (D7C2B8) |
|
(11 hsp) |
0.0 |
2983 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
15
|
Q6W5P7_9ACTO (Q6W5P7) |
|
(10 hsp) |
0.0 |
2964 |
49% |
|
- Product
- FscE
- Gene
- fscE
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
16
|
Q93H87_STRAW (Q93H87) |
|
(11 hsp) |
0.0 |
2930 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
17
|
D6C4C5_9ACTO (D6C4C5) |
|
(4 hsp) |
0.0 |
2929 |
45% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA1
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
18
|
Q82QT4_STRAW (Q82QT4) |
|
(15 hsp) |
0.0 |
2928 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
19
|
D7C488_STRBB (D7C488) |
|
(6 hsp) |
0.0 |
2920 |
45% |
|
- Product
- Type I polyketide synthase
- Gene
- milA1
SBI_00789
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
20
|
Q6W5P9_9ACTO (Q6W5P9) |
|
(9 hsp) |
0.0 |
2882 |
49% |
|
- Product
- FscB
- Gene
- fscB
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
21
|
B1W4J2_STRGG (B1W4J2) |
|
(9 hsp) |
0.0 |
2875 |
48% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-2
SGR_6180
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
22
|
Q9ZGI4_9ACTO (Q9ZGI4) |
|
(5 hsp) |
0.0 |
2869 |
49% |
|
- Product
- Type I polyketide synthase PikAII
- Gene
- pikAII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
23
|
B1W4J4_STRGG (B1W4J4) |
|
(5 hsp) |
0.0 |
2787 |
49% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-4
SGR_6182
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
24
|
B1W489_STRGG (B1W489) |
|
(4 hsp) |
0.0 |
2771 |
50% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-5
SGR_6077
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
25
|
B6ZIR4_STRPT (B6ZIR4) |
|
(4 hsp) |
0.0 |
2751 |
49% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
29
|
Q93HJ5_STRAW (Q93HJ5) |
|
(7 hsp) |
0.0 |
2715 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA1
SAV2899 SAV_2899
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
30
|
A0FCL1_STRVO (A0FCL1) |
|
(10 hsp) |
0.0 |
2715 |
45% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
31
|
Q8KPW3_9ACTO (Q8KPW3) |
|
(4 hsp) |
0.0 |
2706 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSIII
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
32
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(10 hsp) |
0.0 |
2690 |
44% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
35
|
B6ZIR2_STRPT (B6ZIR2) |
|
(8 hsp) |
0.0 |
2642 |
44% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
36
|
Q5SFB4_STRBI (Q5SFB4) |
|
(9 hsp) |
0.0 |
2595 |
44% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGI
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
37
|
A4F7P0_SACEN (A4F7P0) |
|
(7 hsp) |
0.0 |
2592 |
46% |
|
- Product
- EryAII Erythromycin polyketide synthase modules 3 and 4
- Gene
- eryAII
SACE_0723
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] | 2uniprot[Pubmed] 17719492 Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.(Chem. Biol.) [2007] | [pubmed all]
|
38
|
Q5UNP5_SACER (Q5UNP5) |
|
(7 hsp) |
0.0 |
2592 |
46% |
|
- Product
- EryAII
- Gene
- eryAII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
39
|
Q8KPW5_9ACTO (Q8KPW5) |
|
(10 hsp) |
0.0 |
2587 |
44% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSI
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
40
|
ERYA2_SACER (Q03132) |
|
(7 hsp) |
0.0 |
2580 |
46% |
|
- Product
- Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II DEBS 2 ORF 2
- Gene
- eryA
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 2024119 [Medline] 91220065 Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991] | 2uniprot[Pubmed] 1740151 [Medline] 92155230 6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992] | 3uniprot[Pubmed] 1618327 Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992] | 4uniprot[Pubmed] 12954331 The structure of docking domains in modular polyketide synthases.(Chem. Biol.) [2003] | [pubmed all]
|
41
|
A0ACI2_STRAM (A0ACI2) |
|
(4 hsp) |
0.0 |
2579 |
48% |
|
- Product
- Putative modular polyketide synthase
- Gene
- SAMR0476
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
42
|
D1GLV9_9ACTO (D1GLV9) |
|
(12 hsp) |
0.0 |
2514 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
44
|
Q68BG4_STRHA (Q68BG4) |
|
(14 hsp) |
0.0 |
2479 |
51% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
45
|
D1GLV8_9ACTO (D1GLV8) |
|
(8 hsp) |
0.0 |
2475 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
46
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(11 hsp) |
0.0 |
2463 |
49% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
48
|
C9YYI3_STRSW (C9YYI3) |
|
(11 hsp) |
0.0 |
2458 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
49
|
Q9ADL6_SORCE (Q9ADL6) |
|
(10 hsp) |
0.0 |
2455 |
47% |
|
- Product
- Soraphen polyketide synthase A
- Gene
- sorA
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] |
|
51
|
F1DI32_9ACTO (F1DI32) |
|
(7 hsp) |
0.0 |
2453 |
49% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
52
|
D3U9Y7_9ACTO (D3U9Y7) |
|
(6 hsp) |
0.0 |
2452 |
48% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaG
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
54
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(7 hsp) |
0.0 |
2445 |
49% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
55
|
F1DI31_9ACTO (F1DI31) |
|
(11 hsp) |
0.0 |
2444 |
49% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
56
|
Q3S869_9ACTO (Q3S869) |
|
(11 hsp) |
0.0 |
2434 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
57
|
Q9KIV4_STRAT (Q9KIV4) |
|
(10 hsp) |
0.0 |
2433 |
46% |
|
- Product
- 8,8a-deoxyoleandolide synthase 1
- Gene
- oleAI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
61
|
Q9ZGI5_9ACTO (Q9ZGI5) |
|
(7 hsp) |
0.0 |
2410 |
42% |
|
- Product
- Type I polyketide synthase PikAI
- Gene
- pikAI
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
62
|
D7CC08_STRBB (D7CC08) |
|
(10 hsp) |
0.0 |
2404 |
56% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
64
|
D7CC07_STRBB (D7CC07) |
|
(10 hsp) |
0.0 |
2385 |
55% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-1
SBI_01381
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
66
|
Q68BG5_STRHA (Q68BG5) |
|
(9 hsp) |
0.0 |
2370 |
44% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
67
|
C5HV17_STRAT (C5HV17) |
|
(4 hsp) |
0.0 |
2368 |
62% |
|
- Product
- Polyketide synthase
- Gene
- idmO
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
68
|
O30764_9ACTO (O30764) |
|
(5 hsp) |
0.0 |
2361 |
41% |
|
- Product
- Polyketide synthase modules 1 and 2
- Gene
- nidA1
- Organism
- Streptomyces caelestis
|
1uniprot[Pubmed] 9393718 [Medline] 98053867 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.(J. Bacteriol.) [1997] |
|
70
|
Q52V44_9ACTO (Q52V44) |
|
(14 hsp) |
0.0 |
2338 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
71
|
Q52V46_9ACTO (Q52V46) |
|
(17 hsp) |
0.0 |
2333 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
72
|
E0D202_9ACTO (E0D202) |
|
(14 hsp) |
0.0 |
2326 |
48% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
73
|
Q83WE8_MICGR (Q83WE8) |
|
(7 hsp) |
0.0 |
2323 |
45% |
|
- Product
- Protomycinolide IV synthase 3
- Gene
- mycAIII
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
75
|
E0D203_9ACTO (E0D203) |
|
(10 hsp) |
0.0 |
2313 |
49% |
|
- Product
- Polyketide synthase
- Gene
- gfsB
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
76
|
E2Q518_STRCL (E2Q518) |
|
(8 hsp) |
0.0 |
2308 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0012
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
77
|
Q7WTD6_9ACTO (Q7WTD6) |
|
(7 hsp) |
0.0 |
2296 |
47% |
|
- Product
- NanA8
- Gene
- nanA8
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
79
|
E4NJF4_KITSK (E4NJF4) |
|
(8 hsp) |
0.0 |
2296 |
49% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
81
|
D7BSM1_STRBB (D7BSM1) |
|
(7 hsp) |
0.0 |
2288 |
47% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
84
|
F1CLC1_9ACTO (F1CLC1) |
|
(16 hsp) |
0.0 |
2284 |
48% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
85
|
D7BRD7_STRBB (D7BRD7) |
|
(5 hsp) |
0.0 |
2283 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01979
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
86
|
Q52V53_9ACTO (Q52V53) |
|
(13 hsp) |
0.0 |
2280 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
87
|
C0SMW4_9ACTO (C0SMW4) |
|
(24 hsp) |
0.0 |
2279 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
88
|
C9YYI2_STRSW (C9YYI2) |
|
(7 hsp) |
0.0 |
2272 |
54% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
89
|
Q9X993_9ACTO (Q9X993) |
|
(16 hsp) |
0.0 |
2266 |
48% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
90
|
B1W485_STRGG (B1W485) |
|
(11 hsp) |
0.0 |
2259 |
48% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
91
|
A8L4A9_FRASN (A8L4A9) |
|
(8 hsp) |
0.0 |
2256 |
49% |
|
- Product
- Erythronolide synthase
- Gene
- Franean1_3887
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
92
|
B6ZIR3_STRPT (B6ZIR3) |
|
(15 hsp) |
0.0 |
2252 |
45% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
93
|
A4KCE4_9ACTO (A4KCE4) |
|
(20 hsp) |
0.0 |
2251 |
47% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] |
|
94
|
C6ZCS1_9ACTO (C6ZCS1) |
|
(20 hsp) |
0.0 |
2249 |
47% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnA
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
96
|
D7C2C3_STRBB (D7C2C3) |
|
(11 hsp) |
0.0 |
2243 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
97
|
Q6MZ72_MYCUA (Q6MZ72) |
|
(30 hsp) |
0.0 |
2242 |
44% |
|
- Product
- Type I modular polyketide synthase
- Gene
- mlsB
MUP032c
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 14736915 Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004] | 2uniprot[Pubmed] 15758215 Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005] | [pubmed all]
|
99
|
C5HV16_STRAT (C5HV16) |
|
(12 hsp) |
0.0 |
2239 |
69% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
100
|
Q93NX9_9ACTO (Q93NX9) |
|
(20 hsp) |
0.0 |
2234 |
51% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|