BLAST table : Rever_00240

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 E8S0C5_MICSL
(E8S0C5)		 
[query] 5 - 5907 (7030)
[subject] 3323 - 9261 (9937)
(14 hsp)		 0.0 4837   51% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
2
 D9T6W4_MICAI
(D9T6W4)		 
[query] 5 - 5907 (7030)
[subject] 3323 - 9260 (9936)
(14 hsp)		 0.0 4836   51% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
3
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 6732 (7030)
[subject] 1 - 6503 (8301)
(6 hsp)		 0.0 4801   49% Type I polyketide synthase sfaH Streptomyces flaveolus
4
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 1300 - 6733 (7030)
[subject] 1367 - 6978 (7026)
(7 hsp)		 0.0 4446   49% Polyketide synthase pldAII Streptomyces platensis
5
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 1307 - 6737 (7030)
[subject] 2781 - 8305 (10873)
(17 hsp)		 0.0 4373   50% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
6
 A8LUX2_SALAI
(A8LUX2)		 
[query] 35 - 5905 (7030)
[subject] 991 - 6625 (7279)
(15 hsp)		 0.0 4330   48% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
7
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 35 - 4405 (7030)
[subject] 4257 - 8454 (9648)
(17 hsp)		 0.0 4328   57% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
8
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 4403 (7030)
[subject] 3796 - 8095 (10827)
(25 hsp)		 0.0 4327   58% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
9
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 35 - 4405 (7030)
[subject] 4141 - 8334 (9528)
(17 hsp)		 0.0 4323   57% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
10
 E0KFI7_STRVO
(E0KFI7)		 
[query] 1774 - 6729 (7030)
[subject] 35 - 5090 (8538)
(13 hsp)		 0.0 4142   50% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
11
 E0KFI9_STRVO
(E0KFI9)		 
[query] 1302 - 5904 (7030)
[subject] 2750 - 7499 (8238)
(16 hsp)		 0.0 3950   51% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
12
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 4 - 4997 (7030)
[subject] 3 - 5128 (5214)
(7 hsp)		 0.0 3920   49% Polyketide synthase idmN Streptomyces antibioticus
13
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 4 - 5007 (7030)
[subject] 3 - 5161 (5232)
(5 hsp)		 0.0 3914   49% Type I polyketide synthase hlsF Streptomyces halstedii
14
 B1W485_STRGG
(B1W485)		 
[query] 1772 - 6729 (7030)
[subject] 36 - 5045 (5136)
(4 hsp)		 0.0 3867   50% Putative type-I PKS pks1-1
SGR_6073		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
15
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 35 - 4405 (7030)
[subject] 19 - 4383 (4894)
(7 hsp)		 0.0 3848   52% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
16
 Q52V46_9ACTO
(Q52V46)		 
[query] 1307 - 5904 (7030)
[subject] 2740 - 7406 (8147)
(15 hsp)		 0.0 3800   50% Polyketide synthase type I Streptomyces aizunensis
17
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 4 - 5012 (7030)
[subject] 5 - 5066 (5136)
(5 hsp)		 0.0 3798   46% Polyketide synthase tsnAII Streptomyces longisporoflavus
18
 E0KBI2_STRVO
(E0KBI2)		 
[query] 1768 - 5903 (7030)
[subject] 27 - 4199 (4930)
(9 hsp)		 0.0 3768   54% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
19
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1774 - 6373 (7030)
[subject] 34 - 4618 (7102)
(11 hsp)		 0.0 3758   50% Polyketide synthase merB Streptomyces sp. NRRL 30748
20
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 30 - 4400 (7030)
[subject] 1573 - 5924 (6831)
(12 hsp)		 0.0 3746   51% ScnS1 scnS1 Streptomyces chattanoogensis
21
 F8JVX1_STRCT
(F8JVX1)		 
[query] 29 - 5015 (7030)
[subject] 1037 - 6056 (6125)
(12 hsp)		 0.0 3739   47% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
22
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1 - 4405 (7030)
[subject] 1 - 4382 (10917)
(11 hsp)		 0.0 3721   51% AmphC amphC Streptomyces nodosus
23
 E0L044_STRVO
(E0L044)		 
[query] 35 - 4403 (7030)
[subject] 1854 - 6247 (7224)
(11 hsp)		 0.0 3719   51% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
24
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4410 (7030)
[subject] 1 - 4393 (11096)
(16 hsp)		 0.0 3704   51% NysC nysC Streptomyces noursei
25
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1 - 4398 (7030)
[subject] 1 - 4402 (10625)
(14 hsp)		 0.0 3691   52% FscC fscC Streptomyces sp. FR-008
26
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 4396 (7030)
[subject] 2816 - 7221 (9950)
(16 hsp)		 0.0 3689   52% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
27
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 32 - 4400 (7030)
[subject] 1559 - 5888 (6797)
(9 hsp)		 0.0 3685   52% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
28
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 4394 (7030)
[subject] 2552 - 6826 (7746)
(12 hsp)		 0.0 3682   51% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
29
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 1774 - 6373 (7030)
[subject] 34 - 4694 (7178)
(12 hsp)		 0.0 3625   49% MerB merB Streptomyces violaceoniger
30
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 4400 (7030)
[subject] 3 - 4445 (5588)
(6 hsp)		 0.0 3605   50% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
31
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1 - 4404 (7030)
[subject] 1 - 4398 (10876)
(13 hsp)		 0.0 3596   51% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 35 - 4394 (7030)
[subject] 1022 - 5332 (6241)
(10 hsp)		 0.0 3571   51% Polyketide synthase KijS1 Actinomadura kijaniata
33
 F8JUL0_STRCT
(F8JUL0)		 
[query] 35 - 5006 (7030)
[subject] 1030 - 5949 (5950)
(12 hsp)		 0.0 3555   48% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
34
 Q52V44_9ACTO
(Q52V44)		 
[query] 1774 - 5899 (7030)
[subject] 35 - 4224 (6751)
(8 hsp)		 0.0 3539   51% Polyketide synthase type I Streptomyces aizunensis
35
 A4X8L0_SALTO
(A4X8L0)		 
[query] 30 - 4394 (7030)
[subject] 1906 - 6278 (7210)
(9 hsp)		 0.0 3538   50% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
36
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 23 - 4403 (7030)
[subject] 122 - 4500 (7110)
(8 hsp)		 0.0 3506   50% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
37
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 4403 (7030)
[subject] 8 - 4277 (5400)
(5 hsp)		 0.0 3506   50% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
38
 Q52V52_9ACTO
(Q52V52)		 
[query] 36 - 4394 (7030)
[subject] 35 - 4441 (5432)
(9 hsp)		 0.0 3500   49% Polyketide synthase type I Streptomyces aizunensis
39
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 4405 (7030)
[subject] 1 - 4290 (5176)
(5 hsp)		 0.0 3495   50% ObsB Saccharopolyspora spinosa
40
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 4403 (7030)
[subject] 3 - 4190 (5099)
(6 hsp)		 0.0 3493   49% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
41
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 4396 (7030)
[subject] 5251 - 9345 (10223)
(13 hsp)		 0.0 3489   50% Polyketide synthase rapB Streptomyces hygroscopicus
42
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 35 - 4402 (7030)
[subject] 992 - 5145 (6078)
(11 hsp)		 0.0 3482   51% ObsA Saccharopolyspora spinosa
43
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1 - 4399 (7030)
[subject] 1 - 4355 (5255)
(8 hsp)		 0.0 3472   50% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
44
 C0Z477_STRVN
(C0Z477)		 
[query] 32 - 5001 (7030)
[subject] 1058 - 6049 (6130)
(10 hsp)		 0.0 3471   47% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
45
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 4405 (7030)
[subject] 1 - 4198 (5060)
(5 hsp)		 0.0 3465   49% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
46
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 4405 (7030)
[subject] 1 - 4198 (5060)
(5 hsp)		 0.0 3465   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
47
 O52789_AMYMD
(O52789)		 
[query] 1 - 4405 (7030)
[subject] 10 - 4207 (5069)
(5 hsp)		 0.0 3461   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
48
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 4406 (7030)
[subject] 1 - 4421 (5339)
(6 hsp)		 0.0 3454   49% Polyketide synthase natB Streptomyces sp. CS
49
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 1774 - 5941 (7030)
[subject] 34 - 4235 (9498)
(21 hsp)		 0.0 3449   50% ScnS2 scnS2 Streptomyces chattanoogensis
50
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1768 - 5900 (7030)
[subject] 28 - 4199 (9510)
(24 hsp)		 0.0 3439   50% AmphI amphI Streptomyces nodosus
51
 D9T6W1_MICAI
(D9T6W1)		 
[query] 1768 - 5904 (7030)
[subject] 25 - 4184 (6415)
(13 hsp)		 0.0 3430   52% Beta-ketoacyl synthase Micau_2461 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
52
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 35 - 4394 (7030)
[subject] 4895 - 9390 (14130)
(15 hsp)		 0.0 3423   46% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
53
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1770 - 5899 (7030)
[subject] 34 - 4209 (4928)
(9 hsp)		 0.0 3408   51% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
54
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 37 - 4186 (7030)
[subject] 984 - 4993 (5113)
(12 hsp)		 0.0 3398   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
55
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1774 - 5941 (7030)
[subject] 34 - 4242 (9507)
(22 hsp)		 0.0 3387   50% PimS2 protein pimS2 Streptomyces natalensis
56
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1768 - 5899 (7030)
[subject] 28 - 4242 (9477)
(21 hsp)		 0.0 3383   50% NysI nysI Streptomyces noursei
57
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4 - 4406 (7030)
[subject] 3 - 4418 (5321)
(6 hsp)		 0.0 3362   49% Polyketide synthase natC Streptomyces sp. CS
58
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 35 - 4405 (7030)
[subject] 1027 - 5452 (5582)
(11 hsp)		 0.0 3352   46% Polyketide synthase type I becA Streptomyces sp. DSM 21069
59
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 35 - 4399 (7030)
[subject] 1026 - 5444 (6383)
(12 hsp)		 0.0 3343   46% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
60
 D7C2C3_STRBB
(D7C2C3)		 
[query] 1774 - 5902 (7030)
[subject] 34 - 4322 (4868)
(12 hsp)		 0.0 3339   49% Modular polyketide synthase pks3-4
SBI_00656		 Streptomyces bingchenggensis (strain BCW-1)
61
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 30 - 4403 (7030)
[subject] 121 - 4425 (5260)
(6 hsp)		 0.0 3334   48% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
62
 B5L6K8_MICCH
(B5L6K8)		 
[query] 36 - 4330 (7030)
[subject] 1023 - 5323 (6305)
(12 hsp)		 0.0 3329   47% Putative type I polyketide synthase Micromonospora chalcea
63
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 4 - 4394 (7030)
[subject] 3 - 4252 (5157)
(8 hsp)		 0.0 3320   48% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
64
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1768 - 5907 (7030)
[subject] 33 - 4231 (9550)
(22 hsp)		 0.0 3308   50% FscD fscD Streptomyces sp. FR-008
65
 E8WEN5_STRFA
(E8WEN5)		 
[query] 19 - 4394 (7030)
[subject] 22 - 4252 (5156)
(7 hsp)		 0.0 3299   49% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
66
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1768 - 5905 (7030)
[subject] 28 - 4224 (9499)
(22 hsp)		 0.0 3288   50% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
67
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6 - 4394 (7030)
[subject] 5 - 4056 (6260)
(14 hsp)		 0.0 3278   48% Polyketide synthase rapC Streptomyces hygroscopicus
68
 B5L6K9_MICCH
(B5L6K9)		 
[query] 12 - 4405 (7030)
[subject] 1716 - 6112 (7007)
(8 hsp)		 0.0 3278   47% Putative type I polyketide synthase Micromonospora chalcea
69
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 35 - 4394 (7030)
[subject] 4890 - 9405 (12352)
(13 hsp)		 0.0 3276   45% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
70
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4394 (7030)
[subject] 1 - 4335 (5066)
(8 hsp)		 0.0 3201   47% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
71
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 1403 - 4989 (7030)
[subject] 3759 - 7303 (7620)
(15 hsp)		 0.0 3193   54% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
72
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 1403 - 4989 (7030)
[subject] 3716 - 7259 (7576)
(15 hsp)		 0.0 3185   54% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
73
 E9KTB5_STRKN
(E9KTB5)		 
[query] 29 - 4427 (7030)
[subject] 2775 - 6894 (7591)
(11 hsp)		 0.0 3169   48% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
74
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 35 - 4399 (7030)
[subject] 2821 - 6929 (7655)
(13 hsp)		 0.0 3167   48% FkbB Streptomyces sp. MJM7001
75
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 4399 (7030)
[subject] 2812 - 6920 (7646)
(13 hsp)		 0.0 3155   48% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
76
 D9WG07_9ACTO
(D9WG07)		 
[query] 1508 - 5015 (7030)
[subject] 1 - 3593 (3668)
(6 hsp)		 0.0 3149   53% Modular polyketide synthase SSOG_02937 Streptomyces himastatinicus ATCC 53653
77
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 2 - 4394 (7030)
[subject] 3 - 4313 (6872)
(9 hsp)		 0.0 3107   46% Polyketide synthase KijS2 Actinomadura kijaniata
78
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 29 - 4425 (7030)
[subject] 2777 - 6884 (7576)
(11 hsp)		 0.0 3106   47% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
79
 E0L379_STRVO
(E0L379)		 
[query] 3406 - 5257 (7030)
[subject] 1 - 1834 (1834)
(9 hsp)		 0.0 3070   86% 6-deoxyerythronolide-B synthase StrviDRAFT_9357 Streptomyces violaceusniger Tu 4113 2.3.1.94
80
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 29 - 4394 (7030)
[subject] 16 - 4525 (16990)
(20 hsp)		 0.0 3066   43% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
81
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 35 - 3487 (7030)
[subject] 3768 - 7196 (7488)
(10 hsp)		 0.0 3034   53% ObsC Saccharopolyspora spinosa
82
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 29 - 4394 (7030)
[subject] 16 - 4523 (17019)
(24 hsp)		 0.0 3031   43% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
83
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 34 - 4394 (7030)
[subject] 1011 - 5450 (6432)
(14 hsp)		 0.0 3007   46% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
84
 E0KBI1_STRVO
(E0KBI1)		 
[query] 3507 - 6779 (7030)
[subject] 34 - 3406 (3456)
(6 hsp)		 0.0 3006   52% Acyl transferase StrviDRAFT_0196 Streptomyces violaceusniger Tu 4113
85
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 24 - 4410 (7030)
[subject] 3139 - 7119 (7938)
(14 hsp)		 0.0 3001   46% Polyketide synthase rapA Actinoplanes sp. N902-109
86
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 4394 (7030)
[subject] 955 - 4985 (5781)
(15 hsp)		 0.0 2999   45% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
87
 D7P611_CHOCO
(D7P611)		 
[query] 482 - 4394 (7030)
[subject] 985 - 4966 (6255)
(14 hsp)		 0.0 2989   47% TugA tugA Chondromyces crocatus
88
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 4 - 3487 (7030)
[subject] 6 - 3294 (3377)
(5 hsp)		 0.0 2986   51% Polyketide synthase type I becF Streptomyces sp. DSM 21069
89
 A4FH83_SACEN
(A4FH83)		 
[query] 1380 - 5008 (7030)
[subject] 1646 - 5290 (5359)
(10 hsp)		 0.0 2981   50% Type I modular polyketide synthase SACE_4139 Saccharopolyspora erythraea (strain NRRL 23338)
90
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 1380 - 5008 (7030)
[subject] 1646 - 5290 (5359)
(10 hsp)		 0.0 2981   50% Type I PKS pkeAIII Saccharopolyspora erythraea
Streptomyces erythraeus
91
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 3507 - 7022 (7030)
[subject] 33 - 3608 (3613)
(6 hsp)		 0.0 2975   51% Modular polyketide synthase olmA7
SAV2895
SAV_2895		 Streptomyces avermitilis
92
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 3041 - 7022 (7030)
[subject] 1112 - 5269 (5277)
(10 hsp)		 0.0 2974   47% Modular polyketide synthase meiA4 Streptomyces nanchangensis
93
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 4 - 3493 (7030)
[subject] 6 - 3295 (3373)
(5 hsp)		 0.0 2974   51% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
94
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 6 - 3491 (7030)
[subject] 5 - 3507 (3582)
(5 hsp)		 0.0 2960   52% LipPks2 lipPks2 Streptomyces aureofaciens
95
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 4405 (7030)
[subject] 1161 - 5194 (7525)
(10 hsp)		 0.0 2941   46% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
96
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 3042 - 6738 (7030)
[subject] 1095 - 4896 (4970)
(8 hsp)		 0.0 2941   49% Nodular polyketide synthase Streptomyces neyagawaensis
97
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 3140 - 6372 (7030)
[subject] 1706 - 4951 (5710)
(17 hsp)		 0.0 2919   53% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
98
 E0D203_9ACTO
(E0D203)		 Jump to FD891_00020 
[query] 3141 - 6735 (7030)
[subject] 1787 - 5487 (5571)
(11 hsp)		 0.0 2904   50% Polyketide synthase gfsB Streptomyces graminofaciens
99
 Q52V53_9ACTO
(Q52V53)		 
[query] 35 - 3488 (7030)
[subject] 1601 - 5128 (5207)
(9 hsp)		 0.0 2897   50% Polyketide synthase type I Streptomyces aizunensis
100
 C9YYI1_STRSW
(C9YYI1)		 
[query] 3042 - 6780 (7030)
[subject] 1099 - 4937 (4970)
(8 hsp)		 0.0 2893   49% Putative type I polyketide synthase SCAB_83901 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
3
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 6732 (7030)
[subject] 1 - 6503 (8301)
(6 hsp)		 0.0 4801   49%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
4
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 1300 - 6733 (7030)
[subject] 1367 - 6978 (7026)
(7 hsp)		 0.0 4446   49%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
7
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 35 - 4405 (7030)
[subject] 4257 - 8454 (9648)
(17 hsp)		 0.0 4328   57%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
8
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 4403 (7030)
[subject] 3796 - 8095 (10827)
(25 hsp)		 0.0 4327   58%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
9
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 35 - 4405 (7030)
[subject] 4141 - 8334 (9528)
(17 hsp)		 0.0 4323   57%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
12
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 4 - 4997 (7030)
[subject] 3 - 5128 (5214)
(7 hsp)		 0.0 3920   49%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
14
 B1W485_STRGG
(B1W485)		 
[query] 1772 - 6729 (7030)
[subject] 36 - 5045 (5136)
(4 hsp)		 0.0 3867   50%
Product
Putative type-I PKS
Gene
pks1-1
SGR_6073
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
16
 Q52V46_9ACTO
(Q52V46)		 
[query] 1307 - 5904 (7030)
[subject] 2740 - 7406 (8147)
(15 hsp)		 0.0 3800   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
19
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1774 - 6373 (7030)
[subject] 34 - 4618 (7102)
(11 hsp)		 0.0 3758   50%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
20
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 30 - 4400 (7030)
[subject] 1573 - 5924 (6831)
(12 hsp)		 0.0 3746   51%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
22
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1 - 4405 (7030)
[subject] 1 - 4382 (10917)
(11 hsp)		 0.0 3721   51%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
24
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4410 (7030)
[subject] 1 - 4393 (11096)
(16 hsp)		 0.0 3704   51%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
25
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1 - 4398 (7030)
[subject] 1 - 4402 (10625)
(14 hsp)		 0.0 3691   52%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
26
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 4396 (7030)
[subject] 2816 - 7221 (9950)
(16 hsp)		 0.0 3689   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
27
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 32 - 4400 (7030)
[subject] 1559 - 5888 (6797)
(9 hsp)		 0.0 3685   52%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
28
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 4394 (7030)
[subject] 2552 - 6826 (7746)
(12 hsp)		 0.0 3682   51%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
29
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 1774 - 6373 (7030)
[subject] 34 - 4694 (7178)
(12 hsp)		 0.0 3625   49%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
30
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 4400 (7030)
[subject] 3 - 4445 (5588)
(6 hsp)		 0.0 3605   50%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
31
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1 - 4404 (7030)
[subject] 1 - 4398 (10876)
(13 hsp)		 0.0 3596   51%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 35 - 4394 (7030)
[subject] 1022 - 5332 (6241)
(10 hsp)		 0.0 3571   51%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
34
 Q52V44_9ACTO
(Q52V44)		 
[query] 1774 - 5899 (7030)
[subject] 35 - 4224 (6751)
(8 hsp)		 0.0 3539   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
36
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 23 - 4403 (7030)
[subject] 122 - 4500 (7110)
(8 hsp)		 0.0 3506   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
37
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 4403 (7030)
[subject] 8 - 4277 (5400)
(5 hsp)		 0.0 3506   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
38
 Q52V52_9ACTO
(Q52V52)		 
[query] 36 - 4394 (7030)
[subject] 35 - 4441 (5432)
(9 hsp)		 0.0 3500   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
39
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 4405 (7030)
[subject] 1 - 4290 (5176)
(5 hsp)		 0.0 3495   50%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
40
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 4403 (7030)
[subject] 3 - 4190 (5099)
(6 hsp)		 0.0 3493   49%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
41
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 4396 (7030)
[subject] 5251 - 9345 (10223)
(13 hsp)		 0.0 3489   50%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
42
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 35 - 4402 (7030)
[subject] 992 - 5145 (6078)
(11 hsp)		 0.0 3482   51%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
45
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 4405 (7030)
[subject] 1 - 4198 (5060)
(5 hsp)		 0.0 3465   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
46
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 4405 (7030)
[subject] 1 - 4198 (5060)
(5 hsp)		 0.0 3465   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
48
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 4406 (7030)
[subject] 1 - 4421 (5339)
(6 hsp)		 0.0 3454   49%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
49
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 1774 - 5941 (7030)
[subject] 34 - 4235 (9498)
(21 hsp)		 0.0 3449   50%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
50
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1768 - 5900 (7030)
[subject] 28 - 4199 (9510)
(24 hsp)		 0.0 3439   50%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
52
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 35 - 4394 (7030)
[subject] 4895 - 9390 (14130)
(15 hsp)		 0.0 3423   46%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
53
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1770 - 5899 (7030)
[subject] 34 - 4209 (4928)
(9 hsp)		 0.0 3408   51%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
55
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1774 - 5941 (7030)
[subject] 34 - 4242 (9507)
(22 hsp)		 0.0 3387   50%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
56
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1768 - 5899 (7030)
[subject] 28 - 4242 (9477)
(21 hsp)		 0.0 3383   50%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
57
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4 - 4406 (7030)
[subject] 3 - 4418 (5321)
(6 hsp)		 0.0 3362   49%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
58
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 35 - 4405 (7030)
[subject] 1027 - 5452 (5582)
(11 hsp)		 0.0 3352   46%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
59
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 35 - 4399 (7030)
[subject] 1026 - 5444 (6383)
(12 hsp)		 0.0 3343   46%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
60
 D7C2C3_STRBB
(D7C2C3)		 
[query] 1774 - 5902 (7030)
[subject] 34 - 4322 (4868)
(12 hsp)		 0.0 3339   49%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
62
 B5L6K8_MICCH
(B5L6K8)		 
[query] 36 - 4330 (7030)
[subject] 1023 - 5323 (6305)
(12 hsp)		 0.0 3329   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
64
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1768 - 5907 (7030)
[subject] 33 - 4231 (9550)
(22 hsp)		 0.0 3308   50%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
66
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1768 - 5905 (7030)
[subject] 28 - 4224 (9499)
(22 hsp)		 0.0 3288   50%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
67
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6 - 4394 (7030)
[subject] 5 - 4056 (6260)
(14 hsp)		 0.0 3278   48%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
68
 B5L6K9_MICCH
(B5L6K9)		 
[query] 12 - 4405 (7030)
[subject] 1716 - 6112 (7007)
(8 hsp)		 0.0 3278   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
69
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 35 - 4394 (7030)
[subject] 4890 - 9405 (12352)
(13 hsp)		 0.0 3276   45%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
70
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4394 (7030)
[subject] 1 - 4335 (5066)
(8 hsp)		 0.0 3201   47%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
71
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 1403 - 4989 (7030)
[subject] 3759 - 7303 (7620)
(15 hsp)		 0.0 3193   54%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
72
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 1403 - 4989 (7030)
[subject] 3716 - 7259 (7576)
(15 hsp)		 0.0 3185   54%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
73
 E9KTB5_STRKN
(E9KTB5)		 
[query] 29 - 4427 (7030)
[subject] 2775 - 6894 (7591)
(11 hsp)		 0.0 3169   48%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
75
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 4399 (7030)
[subject] 2812 - 6920 (7646)
(13 hsp)		 0.0 3155   48%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
77
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 2 - 4394 (7030)
[subject] 3 - 4313 (6872)
(9 hsp)		 0.0 3107   46%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
78
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 29 - 4425 (7030)
[subject] 2777 - 6884 (7576)
(11 hsp)		 0.0 3106   47%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
80
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 29 - 4394 (7030)
[subject] 16 - 4525 (16990)
(20 hsp)		 0.0 3066   43%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
81
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 35 - 3487 (7030)
[subject] 3768 - 7196 (7488)
(10 hsp)		 0.0 3034   53%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
82
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 29 - 4394 (7030)
[subject] 16 - 4523 (17019)
(24 hsp)		 0.0 3031   43%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
83
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 34 - 4394 (7030)
[subject] 1011 - 5450 (6432)
(14 hsp)		 0.0 3007   46%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
86
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 4394 (7030)
[subject] 955 - 4985 (5781)
(15 hsp)		 0.0 2999   45%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
87
 D7P611_CHOCO
(D7P611)		 
[query] 482 - 4394 (7030)
[subject] 985 - 4966 (6255)
(14 hsp)		 0.0 2989   47%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
88
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 4 - 3487 (7030)
[subject] 6 - 3294 (3377)
(5 hsp)		 0.0 2986   51%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
89
 A4FH83_SACEN
(A4FH83)		 
[query] 1380 - 5008 (7030)
[subject] 1646 - 5290 (5359)
(10 hsp)		 0.0 2981   50%
Product
Type I modular polyketide synthase
Gene
SACE_4139
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
90
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 1380 - 5008 (7030)
[subject] 1646 - 5290 (5359)
(10 hsp)		 0.0 2981   50%
Product
Type I PKS
Gene
pkeAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
91
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 3507 - 7022 (7030)
[subject] 33 - 3608 (3613)
(6 hsp)		 0.0 2975   51%
Product
Modular polyketide synthase
Gene
olmA7
SAV2895
SAV_2895
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
92
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 3041 - 7022 (7030)
[subject] 1112 - 5269 (5277)
(10 hsp)		 0.0 2974   47%
Product
Modular polyketide synthase
Gene
meiA4
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
93
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 4 - 3493 (7030)
[subject] 6 - 3295 (3373)
(5 hsp)		 0.0 2974   51%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
94
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 6 - 3491 (7030)
[subject] 5 - 3507 (3582)
(5 hsp)		 0.0 2960   52%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
95
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 4405 (7030)
[subject] 1161 - 5194 (7525)
(10 hsp)		 0.0 2941   46%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
96
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 3042 - 6738 (7030)
[subject] 1095 - 4896 (4970)
(8 hsp)		 0.0 2941   49%
Product
Nodular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
97
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 3140 - 6372 (7030)
[subject] 1706 - 4951 (5710)
(17 hsp)		 0.0 2919   53%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
98
 E0D203_9ACTO
(E0D203)		 Jump to FD891_00020 
[query] 3141 - 6735 (7030)
[subject] 1787 - 5487 (5571)
(11 hsp)		 0.0 2904   50%
Product
Polyketide synthase
Gene
gfsB
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
99
 Q52V53_9ACTO
(Q52V53)		 
[query] 35 - 3488 (7030)
[subject] 1601 - 5128 (5207)
(9 hsp)		 0.0 2897   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
100
 C9YYI1_STRSW
(C9YYI1)		 
[query] 3042 - 6780 (7030)
[subject] 1099 - 4937 (4970)
(8 hsp)		 0.0 2893   49%
Product
Putative type I polyketide synthase
Gene
SCAB_83901
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]