薬剤耐性

MiFuPへのリンク

マクロライド系抗生物質耐性

NFUNC_0045 Macrolide antibiotic resistance
NRULE_0164 rRNA adenine N-6-methyltransferase
NRULE_0165 23S rRNA (guanine-N(1))-methyltransferase
NRULE_0166 Macrolide-specific efflux protein MacA
NRULE_0167 Macrolide export ATP-binding/permease protein MacB
NRULE_0168 Erythromycin esterase
NRULE_0169 Macrolide 2'-phosphotransferase
NRULE_0170 Macrolide glycosyltransferase

アミノグリコシド系抗生物質耐性

NFUNC_0041 Aminoglycoside resistance (by aminoglycoside N-acetyltransferase)
NRULE_0149 Aminoglycoside N(3')-acetyltransferase
NRULE_0150 Aminoglycoside N(6')-acetyltransferase
NFUNC_0042 Aminoglycoside resistance (by aminoglycoside O-nucleotidyltransferase)
NRULE_0151 Aminoglycoside 6-adenylyltransferase
NRULE_0152 Kanamycin nucleotidyltransferase
NRULE_0153 2''-aminoglycoside nucleotidyltransferase
NRULE_0154 Streptomycin 3''-adenylyltransferase
NFUNC_0043 Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)
NRULE_0155 Streptomycin 6-kinase
NRULE_0156 Aminoglycoside 3'-phosphotransferase
NRULE_0157 Hygromycin-B 7''-O-kinase
NRULE_0174 Hygromycin-B 4-O-kinase
NFUNC_0052 Kanamycin resistance
NRULE_0149 Aminoglycoside N(3')-acetyltransferase
NRULE_0150 Aminoglycoside N(6')-acetyltransferase
NRULE_0152 Kanamycin nucleotidyltransferase
NRULE_0153 2''-aminoglycoside nucleotidyltransferase
NRULE_0156 Aminoglycoside 3'-phosphotransferase
NFUNC_0053 Gentamicin resistance
NRULE_0149 Aminoglycoside N(3')-acetyltransferase
NRULE_0153 2''-aminoglycoside nucleotidyltransferase
NFUNC_0054 Streptomycin resistance
NRULE_0151 Aminoglycoside 6-adenylyltransferase
NRULE_0154 Streptomycin 3''-adenylyltransferase
NRULE_0155 Streptomycin 6-kinase
NRULE_0156 Aminoglycoside 3'-phosphotransferase
NFUNC_0055 Hygromycin resistance
NRULE_0157 Hygromycin-B 7''-O-kinase
NRULE_0174 Hygromycin-B 4-O-kinase

ベータラクタム系抗生物質耐性

NFUNC_0033 Beta-lactam antibiotic resistance
NRULE_0122 Beta-lactamase class A
NRULE_0123 Metallo-beta-lactamase
NRULE_0124 Beta-lactamase class C
NRULE_0125 Beta-lactamase class D
NFUNC_0035 Methicillin resistance
NRULE_0129 Penicillin-binding protein 2'
NRULE_0130 Methicillin resistance MecR1 protein
NRULE_0131 Methicillin resistance regulatory protein MecI
NFUNC_0046 Ampicillin resistance
NRULE_0122 Beta-lactamase class A
NRULE_0123 Metallo-beta-lactamase
NRULE_0125 Beta-lactamase class D
NFUNC_0047 Penicillin resistance
NRULE_0122 Beta-lactamase class A
NRULE_0123 Metallo-beta-lactamase
NRULE_0125 Beta-lactamase class D
NFUNC_0048 Cephalosporin resistance
NRULE_0122 Beta-lactamase class A
NRULE_0123 Metallo-beta-lactamase
NRULE_0124 Beta-lactamase class C

クロラムフェニコール耐性

NFUNC_0025 Chloramphenicol resistance
NRULE_0107 Chloramphenicol acetyltransferase
NRULE_0108 Chloramphenicol acetyltransferase

スルホンアミド耐性

NFUNC_0039 Sulfonamide resistance
NRULE_0145 Sulfonamide-resistant dihydropteroate synthase

トリメトプリム耐性

NFUNC_0040 Trimethoprim resistance
NRULE_0148 Dihydrofolate reductase type 2

ブレオマイシン耐性

NFUNC_0021 Bleomycin resistance
NRULE_0096 Bleomycin resistance protein

ホスホマイシン耐性

NFUNC_0023 Fosfomycin resistance
NRULE_0098 Glutathione transferase FosA
NRULE_0099 Metallothiol transferase FosB
NRULE_0100 Fosfomycin resistance protein FosX

バシトラシン耐性

NFUNC_0022 Bacitracin resistance
NRULE_0097 Undecaprenyl-diphosphatase

ポリミキシン耐性

NFUNC_0036 Polymyxin resistance
NRULE_0132 Bifunctional polymyxin resistance protein ArnA
NRULE_0133 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase
NRULE_0134 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
NRULE_0135 Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
NRULE_0136 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
NRULE_0137 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF
NRULE_0138 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase

ストレプトグラミン系抗生物質耐性

NFUNC_0027 Streptogramin resistance
NRULE_0113 Streptogramin A acetyltransferase
NRULE_0114 Virginiamycin B lyase

バンコマイシン耐性

NFUNC_0089 Vancomycin resistance (via D-Ala-D-Lac precursor)
NRULE_0265 D-alanine--D-lactate ligase
NRULE_0266 D-specific alpha-keto acid dehydrogenase
NRULE_0267 D-alanyl-D-alanine dipeptidase
NRULE_0274 D-alanyl-D-alanine carboxypeptidase
NRULE_0275 D-alanyl-D-alanine carboxypeptidase
NRULE_0276 D-alanyl-D-alanine carboxypeptidase
NRULE_0277 D-alanyl-D-alanine carboxypeptidase
NRULE_0278 D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidase
NRULE_0279 Two-component system response regulator VanR
NRULE_0280 Two-component system response regulator VanR
NRULE_0282 Putative two-component system response regulator VanR
NRULE_0284 Two-component system response regulator VanR
NRULE_0285 Two-component system histidine kinase VanS
NRULE_0286 Two-component system histidine kinase VanS
NRULE_0288 Putative two-component system histidine kinase VanS
NRULE_0289 Putative two-component system histidine kinase VanS
NRULE_0290 Two-component system histidine kinase VanS
NRULE_0291 Teicoplanin resistance protein
NRULE_0292 Putative vancomycin resistance protein
NRULE_0295 Teicoplanin resistance protein
NRULE_0296 Glycyltransferase VanK
NRULE_0297 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-lactate ligase
NFUNC_0090 Vancomycin resistance (via D-Ala-D-Ser precursor)
NRULE_0268 D-alanine--D-serine ligase
NRULE_0269 Serine/alanine racemase
NRULE_0270 D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidase
NRULE_0271 D-alanine--D-serine ligase
NRULE_0272 Serine/alanine racemase
NRULE_0273 D-alanyl-D-alanine dipeptidase
NRULE_0281 Putative two-component system response regulator VanR
NRULE_0283 Putative two-component system response regulator VanR
NRULE_0287 Putative two-component system histidine kinase VanS
NRULE_0293 Putative vancomycin resistance protein
NRULE_0294 Putative transcriptional regulator