| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
B6ZK66_STRLS (B6ZK66) |
|
|
0.0 |
2236 |
100% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd13
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
3
|
B6ZK67_STRLS (B6ZK67) |
|
(2 hsp) |
0.0 |
1449 |
82% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd14
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
6
|
B6ZK69_STRLS (B6ZK69) |
|
(2 hsp) |
0.0 |
1300 |
72% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd16
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
8
|
B6ZK65_STRLS (B6ZK65) |
|
(6 hsp) |
0.0 |
1295 |
75% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd12
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|
11
|
D7CC09_STRBB (D7CC09) |
|
(2 hsp) |
0.0 |
1110 |
63% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-3
SBI_01383
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
17
|
E0D203_9ACTO (E0D203) |
|
(6 hsp) |
0.0 |
1100 |
62% |
|
- Product
- Polyketide synthase
- Gene
- gfsB
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
19
|
D3U9Y6_9ACTO (D3U9Y6) |
|
(5 hsp) |
0.0 |
1097 |
59% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaF
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
20
|
D7CC08_STRBB (D7CC08) |
|
(6 hsp) |
0.0 |
1094 |
62% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
21
|
E0D206_9ACTO (E0D206) |
|
(4 hsp) |
0.0 |
1094 |
61% |
|
- Product
- Polyketide synthase
- Gene
- gfsE
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
22
|
Q3S863_9ACTO (Q3S863) |
|
(4 hsp) |
0.0 |
1093 |
62% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
23
|
Q9ALM4_9PSEU (Q9ALM4) |
|
(4 hsp) |
0.0 |
1092 |
62% |
|
- Product
- Polyketide synthase extender modules 3-4
- Gene
- spnC
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
24
|
Q52V51_9ACTO (Q52V51) |
|
(4 hsp) |
0.0 |
1087 |
62% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
25
|
Q0RTS5_FRAAA (Q0RTS5) |
|
(3 hsp) |
0.0 |
1086 |
55% |
|
- Product
- Putative Type I modular polyketide synthase
- Gene
- FRAAL0347
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
26
|
D7CC10_STRBB (D7CC10) |
|
(2 hsp) |
0.0 |
1086 |
62% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-4
SBI_01384
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
29
|
C9YYI2_STRSW (C9YYI2) |
|
(4 hsp) |
0.0 |
1078 |
61% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
33
|
Q70KH4_9ACTO (Q70KH4) |
|
(3 hsp) |
0.0 |
1071 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
- aurC
- Organism
- Streptomyces thioluteus
|
1uniprot[Pubmed] 14700630 Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster.(Chem. Biol.) [2003] |
|
34
|
E4NJF3_KITSK (E4NJF3) |
|
(4 hsp) |
0.0 |
1068 |
61% |
|
- Product
- Modular polyketide synthase BFAS3
- Gene
- bfmA3
KSE_73460
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
40
|
A4FH83_SACEN (A4FH83) |
|
(6 hsp) |
0.0 |
1063 |
61% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
41
|
Q5VKR4_SACER (Q5VKR4) |
|
(6 hsp) |
0.0 |
1063 |
61% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
42
|
D1GLV8_9ACTO (D1GLV8) |
|
(4 hsp) |
0.0 |
1063 |
60% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
43
|
Q52V47_9ACTO (Q52V47) |
|
(2 hsp) |
0.0 |
1063 |
61% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
44
|
Q84G23_STRHY (Q84G23) |
|
(4 hsp) |
0.0 |
1063 |
61% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
45
|
Q1L0T1_STRHY (Q1L0T1) |
|
(4 hsp) |
0.0 |
1061 |
60% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
48
|
D7P611_CHOCO (D7P611) |
|
(7 hsp) |
0.0 |
1060 |
60% |
|
- Product
- TugA
- Gene
- tugA
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|
49
|
Q49BE0_STRHY (Q49BE0) |
|
(4 hsp) |
0.0 |
1060 |
60% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
50
|
B6ZIR2_STRPT (B6ZIR2) |
|
(7 hsp) |
0.0 |
1060 |
63% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
51
|
A4FH82_SACEN (A4FH82) |
|
(2 hsp) |
0.0 |
1059 |
60% |
|
- Product
- Type I PKS modular polyketide synthas
- Gene
- SACE_4138
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
52
|
Q5VKR3_SACER (Q5VKR3) |
|
(2 hsp) |
0.0 |
1059 |
60% |
|
- Product
- Type I PKS
- Gene
-
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
54
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(4 hsp) |
0.0 |
1055 |
59% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
55
|
Q27W59_STRVO (Q27W59) |
|
(2 hsp) |
0.0 |
1055 |
60% |
|
- Product
- NIGAVIII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
56
|
A1YAN1_AMYOR (A1YAN1) |
|
(2 hsp) |
0.0 |
1054 |
61% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
57
|
B6ZIR3_STRPT (B6ZIR3) |
|
(8 hsp) |
0.0 |
1054 |
60% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
58
|
D7CFC9_STRBB (D7CFC9) |
|
(3 hsp) |
0.0 |
1054 |
61% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SBI_01544
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
64
|
Q9S0R3_STRAW (Q9S0R3) |
|
(6 hsp) |
0.0 |
1046 |
57% |
|
- Product
- Type I polyketide synthase AVES 4
- Gene
- aveA4
SAV943 SAV_943
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 10449723 [Medline] 99380548 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999] | 2uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 3uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
67
|
F1DI32_9ACTO (F1DI32) |
|
(4 hsp) |
0.0 |
1045 |
58% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
68
|
C9YYI1_STRSW (C9YYI1) |
|
(6 hsp) |
0.0 |
1043 |
61% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
69
|
Q7WTD6_9ACTO (Q7WTD6) |
|
(4 hsp) |
0.0 |
1043 |
59% |
|
- Product
- NanA8
- Gene
- nanA8
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
70
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(8 hsp) |
0.0 |
1040 |
62% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
71
|
Q27W68_STRVO (Q27W68) |
|
(2 hsp) |
0.0 |
1039 |
60% |
|
- Product
- NigAVI
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
72
|
B1W487_STRGG (B1W487) |
|
(4 hsp) |
0.0 |
1038 |
60% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-3
SGR_6075
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
73
|
A0FCL2_STRVO (A0FCL2) |
|
(8 hsp) |
0.0 |
1038 |
61% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
74
|
Q27W60_STRVO (Q27W60) |
|
(2 hsp) |
0.0 |
1038 |
59% |
|
- Product
- NigAIX
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
75
|
Q9ZGI3_9ACTO (Q9ZGI3) |
|
(2 hsp) |
0.0 |
1038 |
60% |
|
- Product
- Type I polyketide synthase PikAIII
- Gene
- pikAIII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] | 2uniprot[Pubmed] 19146481 Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.(ACS Chem. Biol.) [2009] | [pubmed all]
|
76
|
D7CC07_STRBB (D7CC07) |
|
(5 hsp) |
0.0 |
1037 |
62% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-1
SBI_01381
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
78
|
A1YAM9_AMYOR (A1YAM9) |
|
(4 hsp) |
0.0 |
1036 |
59% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
80
|
Q0S8W4_RHOSR (Q0S8W4) |
|
(4 hsp) |
0.0 |
1036 |
59% |
|
- Product
- Type I polyketide synthase
- Gene
- RHA1_ro04231
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
81
|
D7BSM1_STRBB (D7BSM1) |
|
(4 hsp) |
0.0 |
1036 |
59% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
83
|
Q3S864_9ACTO (Q3S864) |
|
(6 hsp) |
0.0 |
1036 |
61% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
84
|
Q9ZGI4_9ACTO (Q9ZGI4) |
|
(4 hsp) |
0.0 |
1035 |
59% |
|
- Product
- Type I polyketide synthase PikAII
- Gene
- pikAII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
86
|
D7BRE1_STRBB (D7BRE1) |
|
(7 hsp) |
0.0 |
1034 |
61% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
87
|
D1GLV9_9ACTO (D1GLV9) |
|
(7 hsp) |
0.0 |
1033 |
61% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
88
|
D7CDZ6_STRBB (D7CDZ6) |
|
|
0.0 |
1033 |
60% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SBI_01540
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
89
|
Q9ZGI2_9ACTO (Q9ZGI2) |
|
|
0.0 |
1033 |
54% |
|
- Product
- Type I polyketide synthase PikAIV
- Gene
- pikAIV
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] | 2uniprot[Pubmed] 12379102 [Medline] 22266839 Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.(Biochemistry) [2002] | 3uniprot[Pubmed] 16969373 Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.(Nat. Chem. Biol.) [2006] | 4uniprot[Pubmed] 16969372 Structural basis for macrolactonization by the pikromycin thioesterase.(Nat. Chem. Biol.) [2006] | 5uniprot[Pubmed] 19146481 Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.(ACS Chem. Biol.) [2009] | [pubmed all]
|
90
|
B6ZIR4_STRPT (B6ZIR4) |
|
(4 hsp) |
0.0 |
1032 |
59% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
91
|
A1YAM8_AMYOR (A1YAM8) |
|
(2 hsp) |
0.0 |
1032 |
60% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
92
|
Q0R4M3_STRAT (Q0R4M3) |
|
(4 hsp) |
0.0 |
1031 |
61% |
|
- Product
- ChlA5
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
93
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(6 hsp) |
0.0 |
1031 |
58% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
94
|
C9YYI3_STRSW (C9YYI3) |
|
(6 hsp) |
0.0 |
1030 |
61% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
96
|
E4NJF4_KITSK (E4NJF4) |
|
(4 hsp) |
0.0 |
1029 |
60% |
|
- Product
- Modular polyketide synthase BFAS4
- Gene
- bfmA4
KSE_73470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
97
|
A1YAM7_AMYOR (A1YAM7) |
|
(6 hsp) |
0.0 |
1027 |
62% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
98
|
D7CC12_STRBB (D7CC12) |
|
(2 hsp) |
0.0 |
1027 |
59% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-6
SBI_01386
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
100
|
D7P5Z4_SORCE (D7P5Z4) |
|
(4 hsp) |
0.0 |
1026 |
60% |
|
- Product
- TgaB
- Gene
- tgaB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 20416506 Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010] |
|