BLAST table : Meili_00310

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 D6C477_9ACTO
(D6C477)		 
[query] 1 - 5822 (5822)
[subject] 1 - 5822 (5822)
 0.0 11530   100% Modular polyketide synthase meiA3 Streptomyces nanchangensis
2
 A8J704_9ACTO
(A8J704)		 
[query] 5 - 5818 (5822)
[subject] 1 - 5670 (5674)
 0.0 5838   58% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
3
 D7C432_STRBB
(D7C432)		 
[query] 2825 - 5822 (5822)
[subject] 2832 - 5826 (5826)
(9 hsp)		 0.0 5217   94% Modular polyketide synthase milA3
SBI_00733		 Streptomyces bingchenggensis (strain BCW-1)
4
 Q52V50_9ACTO
(Q52V50)		 
[query] 16 - 5818 (5822)
[subject] 1811 - 7506 (7510)
(5 hsp)		 0.0 5017   52% Polyketide synthase type I Streptomyces aizunensis
5
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 39 - 5822 (5822)
[subject] 137 - 5826 (5826)
(4 hsp)		 0.0 4810   50% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
6
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 7 - 5822 (5822)
[subject] 2 - 5706 (5718)
 0.0 4709   49% ChlA3 Streptomyces antibioticus
7
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 11 - 5819 (5822)
[subject] 6 - 5628 (5630)
 0.0 4697   49% Polyketide synthase tsnAIII Streptomyces longisporoflavus
8
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 39 - 5734 (5822)
[subject] 3501 - 9061 (10917)
(9 hsp)		 0.0 4648   51% AmphC amphC Streptomyces nodosus
9
 E3JBU2_FRASU
(E3JBU2)		 
[query] 36 - 5819 (5822)
[subject] 1810 - 7679 (7679)
(6 hsp)		 0.0 4616   50% Acyl transferase FraEuI1c_4253 Frankia sp. (strain EuI1c)
10
 D7C2B8_STRBB
(D7C2B8)		 
[query] 43 - 5361 (5822)
[subject] 1581 - 6737 (7498)
(12 hsp)		 0.0 4542   51% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
11
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 27 - 5734 (5822)
[subject] 3489 - 9193 (11096)
(8 hsp)		 0.0 4539   50% NysC nysC Streptomyces noursei
12
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5741 (5822)
[subject] 3262 - 8493 (10223)
(8 hsp)		 0.0 4533   49% Polyketide synthase rapB Streptomyces hygroscopicus
13
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 36 - 5734 (5822)
[subject] 1764 - 7196 (7488)
(5 hsp)		 0.0 4516   49% ObsC Saccharopolyspora spinosa
14
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 39 - 5734 (5822)
[subject] 3524 - 9027 (10876)
(9 hsp)		 0.0 4501   51% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
15
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 11 - 5805 (5822)
[subject] 6 - 5636 (5657)
 0.0 4377   47% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
16
 A4FH83_SACEN
(A4FH83)		 
[query] 7 - 4841 (5822)
[subject] 2 - 4647 (5359)
(7 hsp)		 0.0 4375   53% Type I modular polyketide synthase SACE_4139 Saccharopolyspora erythraea (strain NRRL 23338)
17
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 7 - 4841 (5822)
[subject] 2 - 4647 (5359)
(7 hsp)		 0.0 4375   53% Type I PKS pkeAIII Saccharopolyspora erythraea
Streptomyces erythraeus
18
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 39 - 5362 (5822)
[subject] 1308 - 6165 (8563)
(11 hsp)		 0.0 4214   49% Polyketide synthase rapA Streptomyces hygroscopicus
19
 D9T6W3_MICAI
(D9T6W3)		 
[query] 33 - 4849 (5822)
[subject] 2095 - 6815 (7520)
(10 hsp)		 0.0 4177   52% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
20
 E8S0C6_MICSL
(E8S0C6)		 
[query] 33 - 4849 (5822)
[subject] 2095 - 6815 (7520)
(10 hsp)		 0.0 4169   52% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
21
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 34 - 5749 (5822)
[subject] 1212 - 6265 (7938)
(6 hsp)		 0.0 4103   47% Polyketide synthase rapA Actinoplanes sp. N902-109
22
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 38 - 5354 (5822)
[subject] 3621 - 8962 (16990)
(19 hsp)		 0.0 4015   46% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
23
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 38 - 5354 (5822)
[subject] 3619 - 8962 (17019)
(20 hsp)		 0.0 4006   46% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
24
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1789 - 5819 (5822)
[subject] 1488 - 5527 (5532)
(6 hsp)		 0.0 3796   57% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
25
 E0L044_STRVO
(E0L044)		 
[query] 1786 - 5807 (5822)
[subject] 3235 - 7209 (7224)
(8 hsp)		 0.0 3670   53% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
26
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 9 - 5356 (5822)
[subject] 4 - 4704 (6396)
(11 hsp)		 0.0 3669   46% FkbA fkbA Streptomyces hygroscopicus subsp. ascomyceticus
27
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 39 - 4853 (5822)
[subject] 2109 - 6698 (7620)
(15 hsp)		 0.0 3639   48% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
28
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 39 - 4853 (5822)
[subject] 2067 - 6654 (7576)
(15 hsp)		 0.0 3616   48% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
29
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1789 - 5818 (5822)
[subject] 3909 - 7742 (7746)
(13 hsp)		 0.0 3438   51% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
30
 B4VB11_9ACTO
(B4VB11)		 
[query] 1845 - 5789 (5822)
[subject] 2 - 3893 (3928)
(6 hsp)		 0.0 3414   53% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
31
 Q0QMN5_9ACTO
(Q0QMN5)		 
[query] 608 - 4847 (5822)
[subject] 651 - 4705 (5393)
(7 hsp)		 0.0 3403   51% Polyketide synthase type I Streptomyces sp. Eco86
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1785 - 5819 (5822)
[subject] 2386 - 6238 (6241)
(9 hsp)		 0.0 3392   52% Polyketide synthase KijS1 Actinomadura kijaniata
33
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1784 - 5819 (5822)
[subject] 2954 - 6828 (6831)
(9 hsp)		 0.0 3390   51% ScnS1 scnS1 Streptomyces chattanoogensis
34
 Q52V52_9ACTO
(Q52V52)		 
[query] 1786 - 5819 (5822)
[subject] 1422 - 5429 (5432)
(8 hsp)		 0.0 3388   52% Polyketide synthase type I Streptomyces aizunensis
35
 Q52V53_9ACTO
(Q52V53)		 
[query] 1789 - 5819 (5822)
[subject] 1221 - 5204 (5207)
(8 hsp)		 0.0 3382   52% Polyketide synthase type I Streptomyces aizunensis
36
 Q93H87_STRAW
(Q93H87)		 
[query] 1787 - 5818 (5822)
[subject] 2175 - 6044 (6048)
(11 hsp)		 0.0 3361   51% Modular polyketide synthase pteA1 Streptomyces avermitilis
37
 D7BRD4_STRBB
(D7BRD4)		 
[query] 1786 - 5741 (5822)
[subject] 2440 - 6336 (9950)
(11 hsp)		 0.0 3354   52% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
38
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1804 - 5819 (5822)
[subject] 2943 - 6794 (6797)
(10 hsp)		 0.0 3324   51% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
39
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1784 - 5819 (5822)
[subject] 2404 - 6380 (6383)
(9 hsp)		 0.0 3317   49% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
40
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1784 - 5741 (5822)
[subject] 1399 - 5298 (5588)
(6 hsp)		 0.0 3316   51% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
41
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 39 - 3931 (5822)
[subject] 3277 - 7021 (7102)
(10 hsp)		 0.0 3311   51% Polyketide synthase merB Streptomyces sp. NRRL 30748
42
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 39 - 3931 (5822)
[subject] 3322 - 7097 (7178)
(11 hsp)		 0.0 3298   51% MerB merB Streptomyces violaceoniger
43
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1786 - 5819 (5822)
[subject] 1322 - 5096 (5099)
(7 hsp)		 0.0 3285   51% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
44
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 25 - 3927 (5822)
[subject] 20 - 3856 (3939)
(3 hsp)		 0.0 3283   52% Modular polyketide synthase olmA3
SAV2897
SAV_2897		 Streptomyces avermitilis
45
 E0KRC7_STRVO
(E0KRC7)		 
[query] 39 - 3932 (5822)
[subject] 1731 - 5479 (5559)
(10 hsp)		 0.0 3271   51% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
46
 D9T6W4_MICAI
(D9T6W4)		 
[query] 1799 - 5746 (5822)
[subject] 2988 - 6831 (9936)
(18 hsp)		 0.0 3269   50% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
47
 E8S0C5_MICSL
(E8S0C5)		 
[query] 1799 - 5735 (5822)
[subject] 2988 - 6820 (9937)
(18 hsp)		 0.0 3261   50% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
48
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 9 - 3935 (5822)
[subject] 3 - 3865 (3936)
(4 hsp)		 0.0 3256   50% ChlA5 Streptomyces antibioticus
49
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 39 - 3931 (5822)
[subject] 7422 - 11206 (11604)
(24 hsp)		 0.0 3246   51% MerC merC Streptomyces violaceoniger
50
 D7F1M2_9ACTO
(D7F1M2)		 
[query] 39 - 3931 (5822)
[subject] 2139 - 5941 (6036)
(8 hsp)		 0.0 3241   50% Polyketide synthase tsnAIV Streptomyces longisporoflavus
51
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1802 - 5723 (5822)
[subject] 1522 - 5296 (7110)
(7 hsp)		 0.0 3237   51% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
52
 B5L6M3_MICCH
(B5L6M3)		 
[query] 2 - 3931 (5822)
[subject] 7 - 3873 (3953)
(4 hsp)		 0.0 3233   50% Putative type I polyketide synthase Micromonospora chalcea
53
 E0KRC6_STRVO
(E0KRC6)		 
[query] 39 - 3931 (5822)
[subject] 7379 - 11065 (11118)
(25 hsp)		 0.0 3232   51% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
54
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1788 - 5820 (5822)
[subject] 1206 - 5217 (5220)
(7 hsp)		 0.0 3226   49% Type I polyketide synthase hlsC Streptomyces halstedii
55
 C0Z473_STRVN
(C0Z473)		 
[query] 24 - 3932 (5822)
[subject] 2 - 3860 (3973)
(5 hsp)		 0.0 3209   51% Type I polyketide synthase, modules 4-5 ken12 Streptomyces violaceoruber
56
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 1786 - 5312 (5822)
[subject] 1396 - 4847 (4894)
(6 hsp)		 0.0 3207   53% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
57
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1805 - 5819 (5822)
[subject] 2421 - 6302 (6305)
(9 hsp)		 0.0 3205   49% Putative type I polyketide synthase Micromonospora chalcea
58
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 2 - 3932 (5822)
[subject] 7 - 3847 (3921)
(4 hsp)		 0.0 3201   50% Polyketide synthase KijS4 Actinomadura kijaniata
59
 F8JUL0_STRCT
(F8JUL0)		 
[query] 2048 - 5735 (5822)
[subject] 918 - 4426 (5950)
(13 hsp)		 0.0 3192   53% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
60
 Q52V49_9ACTO
(Q52V49)		 
[query] 2160 - 5749 (5822)
[subject] 26 - 3591 (3872)
(5 hsp)		 0.0 3181   53% Polyketide synthase type I Streptomyces aizunensis
61
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1804 - 5754 (5822)
[subject] 1432 - 5252 (10625)
(13 hsp)		 0.0 3175   50% FscC fscC Streptomyces sp. FR-008
62
 Q82QT5_STRAW
(Q82QT5)		 
[query] 2165 - 5819 (5822)
[subject] 32 - 3561 (3564)
(5 hsp)		 0.0 3173   52% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
63
 E0L075_STRVO
(E0L075)		 
[query] 39 - 3434 (5822)
[subject] 1801 - 5123 (5786)
(11 hsp)		 0.0 3167   54% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
64
 Q93H86_STRAW
(Q93H86)		 
[query] 2174 - 5819 (5822)
[subject] 1 - 3521 (3524)
(4 hsp)		 0.0 3165   52% Modular polyketide synthase pteA2 Streptomyces avermitilis
65
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1827 - 5740 (5822)
[subject] 2267 - 5980 (6078)
(11 hsp)		 0.0 3163   49% ObsA Saccharopolyspora spinosa
66
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 5 - 3932 (5822)
[subject] 1 - 3863 (3888)
(4 hsp)		 0.0 3161   50% GelC Streptomyces hygroscopicus subsp. duamyceticus
67
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 5 - 3932 (5822)
[subject] 1 - 3871 (3896)
(4 hsp)		 0.0 3160   49% GdmAIII gdmAIII Streptomyces hygroscopicus
68
 A4X8L0_SALTO
(A4X8L0)		 
[query] 1789 - 5819 (5822)
[subject] 3270 - 7206 (7210)
(8 hsp)		 0.0 3149   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
69
 F1CT53_9ACTO
(F1CT53)		 
[query] 5 - 3943 (5822)
[subject] 1 - 3859 (3872)
(4 hsp)		 0.0 3140   50% GdmAIII gdmAIII Streptomyces autolyticus
70
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 2169 - 5734 (5822)
[subject] 40 - 3605 (7026)
(11 hsp)		 0.0 3139   52% Polyketide synthase pldAII Streptomyces platensis
71
 Q49BD9_STRHY
(Q49BD9)		 Jump to Herb_00190 
[query] 5 - 3932 (5822)
[subject] 1 - 3863 (3868)
(4 hsp)		 0.0 3115   49% HbmAIII hbmAIII Streptomyces hygroscopicus
72
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 2167 - 5734 (5822)
[subject] 34 - 3534 (3612)
(5 hsp)		 0.0 3113   51% LipPks3 lipPks3 Streptomyces aureofaciens
73
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1787 - 5819 (5822)
[subject] 1405 - 5336 (5339)
(6 hsp)		 0.0 3106   48% Polyketide synthase natB Streptomyces sp. CS
74
 D7P611_CHOCO
(D7P611)		 
[query] 1788 - 5358 (5822)
[subject] 1929 - 5472 (6255)
(11 hsp)		 0.0 3104   51% TugA tugA Chondromyces crocatus
75
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1782 - 5360 (5822)
[subject] 2194 - 5765 (6532)
(14 hsp)		 0.0 3104   52% Polyketide synthase pldAI Streptomyces platensis
76
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1789 - 5734 (5822)
[subject] 1367 - 5110 (5400)
(6 hsp)		 0.0 3102   50% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
77
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 2160 - 5735 (5822)
[subject] 27 - 3579 (5214)
(8 hsp)		 0.0 3095   51% Polyketide synthase idmN Streptomyces antibioticus
78
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 30 - 3918 (5822)
[subject] 1746 - 5460 (5770)
(8 hsp)		 0.0 3093   49% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
79
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 39 - 3931 (5822)
[subject] 1598 - 5460 (5541)
(9 hsp)		 0.0 3092   50% FscB fscB Streptomyces sp. FR-008
80
 E0KLD7_STRVO
(E0KLD7)		 
[query] 5 - 3932 (5822)
[subject] 1 - 3862 (3867)
(4 hsp)		 0.0 3089   49% (Acyl-carrier-protein) S-malonyltransferase., 6-deoxyerythronolide-B synthase StrviDRAFT_3410 Streptomyces violaceusniger Tu 4113 2.3.1.39

2.3.1.94
81
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 2160 - 5819 (5822)
[subject] 27 - 3636 (3639)
(4 hsp)		 0.0 3089   50% Polyketide synthase gfsD Streptomyces graminofaciens
82
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 39 - 3949 (5822)
[subject] 1798 - 5575 (5644)
(7 hsp)		 0.0 3080   49% AmphJ amphJ Streptomyces nodosus
83
 A0PQM7_MYCUA
(A0PQM7)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3408 (4191)
(7 hsp)		 0.0 3072   51% Polyketide synthase, Pks12 pks12
MUL_2266		 Mycobacterium ulcerans (strain Agy99)
84
 B2HF44_MYCMM
(B2HF44)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3404 (4187)
(7 hsp)		 0.0 3070   51% Polyketide synthase, Pks12 pks12
MMAR_3025		 Mycobacterium marinum (strain ATCC BAA-535 / M)
85
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1786 - 5735 (5822)
[subject] 3098 - 6934 (7007)
(7 hsp)		 0.0 3066   49% Putative type I polyketide synthase Micromonospora chalcea
86
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1767 - 5818 (5822)
[subject] 1330 - 5176 (5176)
(5 hsp)		 0.0 3060   47% ObsB Saccharopolyspora spinosa
87
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1762 - 5734 (5822)
[subject] 6294 - 10272 (14130)
(19 hsp)		 0.0 3041   47% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
88
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1805 - 5818 (5822)
[subject] 1409 - 5318 (5321)
(5 hsp)		 0.0 3038   48% Polyketide synthase natC Streptomyces sp. CS
89
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 2073 - 5816 (5822)
[subject] 925 - 4554 (4557)
(8 hsp)		 0.0 3021   49% Putative type I polyketide synthase SCO6275 Streptomyces coelicolor
90
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 2044 - 5735 (5822)
[subject] 905 - 4545 (5582)
(8 hsp)		 0.0 3019   49% Polyketide synthase type I becA Streptomyces sp. DSM 21069
91
 D6EJM4_STRLI
(D6EJM4)		 
[query] 2073 - 5816 (5822)
[subject] 969 - 4596 (4599)
(8 hsp)		 0.0 3008   49% Type I polyketide synthase SSPG_01356 Streptomyces lividans TK24
92
 Q7VES2_MYCBO
(Q7VES2)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 3007   51% Probable polyketide synthase pks12 pks12
Mb2074c		 Mycobacterium bovis
93
 Q0ILD2_9ACTO
(Q0ILD2)		 
[query] 293 - 3927 (5822)
[subject] 194 - 3748 (3835)
(5 hsp)		 0.0 3006   51% NlmA3 nlmA3 Streptomyces nanchangensis
94
 F1CT51_9ACTO
(F1CT51)		 
[query] 22 - 3554 (5822)
[subject] 1104 - 4528 (6840)
(12 hsp)		 0.0 3004   51% GdmAI gdmAI Streptomyces autolyticus
95
 C1APW8_MYCBT
(C1APW8)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 2999   51% Putative polyketide synthase pks12
JTY_2062		 Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
96
 A5WP27_MYCTF
(A5WP27)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 2999   51% Putative uncharacterized protein TBFG_12085 Mycobacterium tuberculosis (strain F11)
97
 A1KK94_MYCBP
(A1KK94)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 2999   51% Probable polyketide synthase pks12 pks12
BCG_2067c		 Mycobacterium bovis (strain BCG / Pasteur 1173P2)
98
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1787 - 5745 (5822)
[subject] 1380 - 5192 (5255)
(6 hsp)		 0.0 2998   48% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
99
 C6DQ18_MYCTK
(C6DQ18)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3370 (4152)
(7 hsp)		 0.0 2994   51% Putative uncharacterized protein TBMG_01933 Mycobacterium tuberculosis (strain KZN 1435 / MDR)
100
 F2GDY9_MYCTU
(F2GDY9)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3370 (4152)
(7 hsp)		 0.0 2994   51% Polyketide synthase pks12 TBSG_01946 Mycobacterium tuberculosis KZN 4207
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 D6C477_9ACTO
(D6C477)		 
[query] 1 - 5822 (5822)
[subject] 1 - 5822 (5822)
 0.0 11530   100%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
3
 D7C432_STRBB
(D7C432)		 
[query] 2825 - 5822 (5822)
[subject] 2832 - 5826 (5826)
(9 hsp)		 0.0 5217   94%
Product
Modular polyketide synthase
Gene
milA3
SBI_00733
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
4
 Q52V50_9ACTO
(Q52V50)		 
[query] 16 - 5818 (5822)
[subject] 1811 - 7506 (7510)
(5 hsp)		 0.0 5017   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
5
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 39 - 5822 (5822)
[subject] 137 - 5826 (5826)
(4 hsp)		 0.0 4810   50%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
6
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 7 - 5822 (5822)
[subject] 2 - 5706 (5718)
 0.0 4709   49%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
8
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 39 - 5734 (5822)
[subject] 3501 - 9061 (10917)
(9 hsp)		 0.0 4648   51%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
10
 D7C2B8_STRBB
(D7C2B8)		 
[query] 43 - 5361 (5822)
[subject] 1581 - 6737 (7498)
(12 hsp)		 0.0 4542   51%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
11
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 27 - 5734 (5822)
[subject] 3489 - 9193 (11096)
(8 hsp)		 0.0 4539   50%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
12
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5741 (5822)
[subject] 3262 - 8493 (10223)
(8 hsp)		 0.0 4533   49%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
13
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 36 - 5734 (5822)
[subject] 1764 - 7196 (7488)
(5 hsp)		 0.0 4516   49%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
14
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 39 - 5734 (5822)
[subject] 3524 - 9027 (10876)
(9 hsp)		 0.0 4501   51%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
16
 A4FH83_SACEN
(A4FH83)		 
[query] 7 - 4841 (5822)
[subject] 2 - 4647 (5359)
(7 hsp)		 0.0 4375   53%
Product
Type I modular polyketide synthase
Gene
SACE_4139
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
17
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 7 - 4841 (5822)
[subject] 2 - 4647 (5359)
(7 hsp)		 0.0 4375   53%
Product
Type I PKS
Gene
pkeAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
18
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 39 - 5362 (5822)
[subject] 1308 - 6165 (8563)
(11 hsp)		 0.0 4214   49%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
22
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 38 - 5354 (5822)
[subject] 3621 - 8962 (16990)
(19 hsp)		 0.0 4015   46%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
23
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 38 - 5354 (5822)
[subject] 3619 - 8962 (17019)
(20 hsp)		 0.0 4006   46%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
24
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1789 - 5819 (5822)
[subject] 1488 - 5527 (5532)
(6 hsp)		 0.0 3796   57%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
26
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 9 - 5356 (5822)
[subject] 4 - 4704 (6396)
(11 hsp)		 0.0 3669   46%
Product
FkbA
Gene
fkbA
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
27
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 39 - 4853 (5822)
[subject] 2109 - 6698 (7620)
(15 hsp)		 0.0 3639   48%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
28
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 39 - 4853 (5822)
[subject] 2067 - 6654 (7576)
(15 hsp)		 0.0 3616   48%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
29
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1789 - 5818 (5822)
[subject] 3909 - 7742 (7746)
(13 hsp)		 0.0 3438   51%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
31
 Q0QMN5_9ACTO
(Q0QMN5)		 
[query] 608 - 4847 (5822)
[subject] 651 - 4705 (5393)
(7 hsp)		 0.0 3403   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces sp. Eco86
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1785 - 5819 (5822)
[subject] 2386 - 6238 (6241)
(9 hsp)		 0.0 3392   52%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
33
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1784 - 5819 (5822)
[subject] 2954 - 6828 (6831)
(9 hsp)		 0.0 3390   51%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
34
 Q52V52_9ACTO
(Q52V52)		 
[query] 1786 - 5819 (5822)
[subject] 1422 - 5429 (5432)
(8 hsp)		 0.0 3388   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
35
 Q52V53_9ACTO
(Q52V53)		 
[query] 1789 - 5819 (5822)
[subject] 1221 - 5204 (5207)
(8 hsp)		 0.0 3382   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
36
 Q93H87_STRAW
(Q93H87)		 
[query] 1787 - 5818 (5822)
[subject] 2175 - 6044 (6048)
(11 hsp)		 0.0 3361   51%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
37
 D7BRD4_STRBB
(D7BRD4)		 
[query] 1786 - 5741 (5822)
[subject] 2440 - 6336 (9950)
(11 hsp)		 0.0 3354   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
38
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1804 - 5819 (5822)
[subject] 2943 - 6794 (6797)
(10 hsp)		 0.0 3324   51%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
39
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1784 - 5819 (5822)
[subject] 2404 - 6380 (6383)
(9 hsp)		 0.0 3317   49%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
40
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1784 - 5741 (5822)
[subject] 1399 - 5298 (5588)
(6 hsp)		 0.0 3316   51%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
41
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 39 - 3931 (5822)
[subject] 3277 - 7021 (7102)
(10 hsp)		 0.0 3311   51%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
42
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 39 - 3931 (5822)
[subject] 3322 - 7097 (7178)
(11 hsp)		 0.0 3298   51%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
43
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1786 - 5819 (5822)
[subject] 1322 - 5096 (5099)
(7 hsp)		 0.0 3285   51%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
44
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 25 - 3927 (5822)
[subject] 20 - 3856 (3939)
(3 hsp)		 0.0 3283   52%
Product
Modular polyketide synthase
Gene
olmA3
SAV2897
SAV_2897
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
48
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 9 - 3935 (5822)
[subject] 3 - 3865 (3936)
(4 hsp)		 0.0 3256   50%
Product
ChlA5
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
49
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 39 - 3931 (5822)
[subject] 7422 - 11206 (11604)
(24 hsp)		 0.0 3246   51%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
51
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1802 - 5723 (5822)
[subject] 1522 - 5296 (7110)
(7 hsp)		 0.0 3237   51%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
52
 B5L6M3_MICCH
(B5L6M3)		 
[query] 2 - 3931 (5822)
[subject] 7 - 3873 (3953)
(4 hsp)		 0.0 3233   50%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
57
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1805 - 5819 (5822)
[subject] 2421 - 6302 (6305)
(9 hsp)		 0.0 3205   49%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
58
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 2 - 3932 (5822)
[subject] 7 - 3847 (3921)
(4 hsp)		 0.0 3201   50%
Product
Polyketide synthase
Gene
KijS4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
60
 Q52V49_9ACTO
(Q52V49)		 
[query] 2160 - 5749 (5822)
[subject] 26 - 3591 (3872)
(5 hsp)		 0.0 3181   53%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
61
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 1804 - 5754 (5822)
[subject] 1432 - 5252 (10625)
(13 hsp)		 0.0 3175   50%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
62
 Q82QT5_STRAW
(Q82QT5)		 
[query] 2165 - 5819 (5822)
[subject] 32 - 3561 (3564)
(5 hsp)		 0.0 3173   52%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
64
 Q93H86_STRAW
(Q93H86)		 
[query] 2174 - 5819 (5822)
[subject] 1 - 3521 (3524)
(4 hsp)		 0.0 3165   52%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
65
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1827 - 5740 (5822)
[subject] 2267 - 5980 (6078)
(11 hsp)		 0.0 3163   49%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
66
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 5 - 3932 (5822)
[subject] 1 - 3863 (3888)
(4 hsp)		 0.0 3161   50%
Product
GelC
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
67
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 5 - 3932 (5822)
[subject] 1 - 3871 (3896)
(4 hsp)		 0.0 3160   49%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
69
 F1CT53_9ACTO
(F1CT53)		 
[query] 5 - 3943 (5822)
[subject] 1 - 3859 (3872)
(4 hsp)		 0.0 3140   50%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
70
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 2169 - 5734 (5822)
[subject] 40 - 3605 (7026)
(11 hsp)		 0.0 3139   52%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
71
 Q49BD9_STRHY
(Q49BD9)		 Jump to Herb_00190 
[query] 5 - 3932 (5822)
[subject] 1 - 3863 (3868)
(4 hsp)		 0.0 3115   49%
Product
HbmAIII
Gene
hbmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
72
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 2167 - 5734 (5822)
[subject] 34 - 3534 (3612)
(5 hsp)		 0.0 3113   51%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
73
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1787 - 5819 (5822)
[subject] 1405 - 5336 (5339)
(6 hsp)		 0.0 3106   48%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
74
 D7P611_CHOCO
(D7P611)		 
[query] 1788 - 5358 (5822)
[subject] 1929 - 5472 (6255)
(11 hsp)		 0.0 3104   51%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
75
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1782 - 5360 (5822)
[subject] 2194 - 5765 (6532)
(14 hsp)		 0.0 3104   52%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
76
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1789 - 5734 (5822)
[subject] 1367 - 5110 (5400)
(6 hsp)		 0.0 3102   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
77
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 2160 - 5735 (5822)
[subject] 27 - 3579 (5214)
(8 hsp)		 0.0 3095   51%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
78
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 30 - 3918 (5822)
[subject] 1746 - 5460 (5770)
(8 hsp)		 0.0 3093   49%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
79
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 39 - 3931 (5822)
[subject] 1598 - 5460 (5541)
(9 hsp)		 0.0 3092   50%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
81
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 2160 - 5819 (5822)
[subject] 27 - 3636 (3639)
(4 hsp)		 0.0 3089   50%
Product
Polyketide synthase
Gene
gfsD
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
82
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 39 - 3949 (5822)
[subject] 1798 - 5575 (5644)
(7 hsp)		 0.0 3080   49%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
83
 A0PQM7_MYCUA
(A0PQM7)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3408 (4191)
(7 hsp)		 0.0 3072   51%
Product
Polyketide synthase, Pks12
Gene
pks12
MUL_2266
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 17210928
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007]
84
 B2HF44_MYCMM
(B2HF44)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3404 (4187)
(7 hsp)		 0.0 3070   51%
Product
Polyketide synthase, Pks12
Gene
pks12
MMAR_3025
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
85
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1786 - 5735 (5822)
[subject] 3098 - 6934 (7007)
(7 hsp)		 0.0 3066   49%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
86
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1767 - 5818 (5822)
[subject] 1330 - 5176 (5176)
(5 hsp)		 0.0 3060   47%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
87
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1762 - 5734 (5822)
[subject] 6294 - 10272 (14130)
(19 hsp)		 0.0 3041   47%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
88
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1805 - 5818 (5822)
[subject] 1409 - 5318 (5321)
(5 hsp)		 0.0 3038   48%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
89
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 2073 - 5816 (5822)
[subject] 925 - 4554 (4557)
(8 hsp)		 0.0 3021   49%
Product
Putative type I polyketide synthase
Gene
SCO6275
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
90
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 2044 - 5735 (5822)
[subject] 905 - 4545 (5582)
(8 hsp)		 0.0 3019   49%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
92
 Q7VES2_MYCBO
(Q7VES2)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 3007   51%
Product
Probable polyketide synthase pks12
Gene
pks12
Mb2074c
Organism
Mycobacterium bovis
1uniprot[Pubmed] 12788972 [Medline] 22709107
The complete genome sequence of Mycobacterium bovis.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
94
 F1CT51_9ACTO
(F1CT51)		 
[query] 22 - 3554 (5822)
[subject] 1104 - 4528 (6840)
(12 hsp)		 0.0 3004   51%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
95
 C1APW8_MYCBT
(C1APW8)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 2999   51%
Product
Putative polyketide synthase
Gene
pks12
JTY_2062
Organism
Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
1uniprot[Pubmed] 19200449
Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009]
97
 A1KK94_MYCBP
(A1KK94)		 
[query] 14 - 3554 (5822)
[subject] 10 - 3369 (4151)
(7 hsp)		 0.0 2999   51%
Product
Probable polyketide synthase pks12
Gene
pks12
BCG_2067c
Organism
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
1uniprot[Pubmed] 17372194
Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007]