Acid resistance (by GABA antiporter) (NFUNC_0071)
必須 A GAD
(NRULE_0231)
Glutamate decarboxylase WFL_18460 WFL_07935
GADC
(NRULE_0234)
Glutamate/gamma-aminobutyrate antiporter WFL_07930
Alanine racemization (NFUNC_0063)
必須 A ALR
(NRULE_0228)
Alanine racemase WFL_21485 WFL_06245
Anthranilate biosynthesis (NFUNC_0038)
必須 A GLAT
(NRULE_0142)
Glutamine amidotransferase WFL_06605 WFL_17660
TRPE
(NRULE_0143)
Anthranilate synthase component I WFL_06610
Aromatic azo compounds degradation (NFUNC_0073)
必須 A AZOR
(NRULE_0236)
FMN-dependent NADH-azoreductase WFL_07530
Arsenical resistance (NFUNC_0004)
必須 A ARSB1
(NRULE_0015)
Arsenical pump membrane protein WFL_18375
ARSC1
(NRULE_0017)
Arsenate reductase WFL_13315 WFL_18380
Bacitracin resistance (NFUNC_0022)
必須 A UPPP
(NRULE_0097)
Undecaprenyl-diphosphatase WFL_16240
Beta-lactam antibiotic resistance (NFUNC_0033)
必須 C BLAC
(NRULE_0124)
Beta-lactamase class C WFL_21965
Betaine biosynthesis (from choline) (NFUNC_0049)
必須 A BETA
(NRULE_0175)
Choline dehydrogenase WFL_01890
Biotin biosynthesis (NFUNC_0051)
必須 A BIOF
(NRULE_0182)
8-amino-7-oxononanoate synthase WFL_04030
BIOA
(NRULE_0183)
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase WFL_04020
BIOD
(NRULE_0184)
ATP-dependent dethiobiotin synthetase BioD WFL_04040 WFL_08610
BIOB
(NRULE_0185)
Biotin synthase WFL_04025
Cephalosporin resistance (NFUNC_0048)
必須 A BLAC
(NRULE_0124)
Beta-lactamase class C WFL_21965
Dihydroxy aromatic compounds degradation (via meta-cleavage pathway) (NFUNC_0011)
必須 A EDIO
(NRULE_0058)
extradiol dioxygenase WFL_02095 WFL_16155 WFL_22950
METAH
(NRULE_0059)
meta-cleavage compound hydrolase WFL_02100
HPDH
(NRULE_0063)
2-hydroxypent-2,4-dienoate hydratase WFL_02105
HOA
(NRULE_0064)
4-hydroxy-2-oxovalerate aldolase WFL_02115
ACDH
(NRULE_0065)
Acetaldehyde dehydrogenase WFL_02110
Folate biosynthesis (NFUNC_0044)
必須 A GLAT
(NRULE_0142)
Glutamine amidotransferase WFL_06605 WFL_17660
DHPS
(NRULE_0144)
Dihydropteroate synthase WFL_16870
FOLM
(NRULE_0146)
Dihydrofolate reductase FolM WFL_08675
FOLB
(NRULE_0158)
Dihydroneopterin aldolase WFL_12200 WFL_16245
FOLK
(NRULE_0159)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase WFL_00685
FOLC
(NRULE_0160)
Bifunctional protein FolC WFL_12260
PABB
(NRULE_0161)
Para-aminobenzoate synthase component I WFL_09735
PABC
(NRULE_0162)
Aminodeoxychorismate lyase WFL_05880
B GLAT
(NRULE_0142)
Glutamine amidotransferase WFL_06605 WFL_17660
DHPS
(NRULE_0144)
Dihydropteroate synthase WFL_16870
FOLA
(NRULE_0147)
Dihydrofolate reductase WFL_00240
FOLB
(NRULE_0158)
Dihydroneopterin aldolase WFL_16245 WFL_12200
FOLK
(NRULE_0159)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase WFL_00685
FOLC
(NRULE_0160)
Bifunctional protein FolC WFL_12260
PABB
(NRULE_0161)
Para-aminobenzoate synthase component I WFL_09735
PABC
(NRULE_0162)
Aminodeoxychorismate lyase WFL_05880
GABA biosynthesis (NFUNC_0066)
必須 A GAD
(NRULE_0231)
Glutamate decarboxylase WFL_07935 WFL_18460
4-hydroxyphenylacetate degradation (NFUNC_0068)
必須 A HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component WFL_22920
HPAC
(NRULE_0102)
4-hydroxyphenylacetate 3-monooxygenase reductase component WFL_22915
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase WFL_22950
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase WFL_22955
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase WFL_22945
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase WFL_22960
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase WFL_22940
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase WFL_22935
C HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component WFL_22920
FADR1
(NRULE_0101)
NADH-dependent flavin reductase WFL_07780 WFL_05450 WFL_22915
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase WFL_22950
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase WFL_22955
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase WFL_22945
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase WFL_22960
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase WFL_22940
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase WFL_22935
Macrolide antibiotic resistance (NFUNC_0045)
必須 B RLMA
(NRULE_0165)
23S rRNA (guanine-N(1))-methyltransferase WFL_09785
C MACA
(NRULE_0166)
Macrolide-specific efflux protein MacA WFL_04805
MACB
(NRULE_0167)
Macrolide export ATP-binding/permease protein MacB WFL_04810
Metal-binding protein (NFUNC_0105)
必須 A MOP
(NRULE_0322)
Putative molybdenum-binding protein WFL_03975 WFL_03955 WFL_06895
B MODE
(NRULE_0323)
Putative molybdate-dependent transcriptional regulator WFL_03955
C MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding protein WFL_03965 WFL_21385 WFL_12990 WFL_20815
E CUER
(NRULE_0328)
Copper-responsive transcriptional regulator CueR WFL_02775
F SOXR
(NRULE_0329)
Redox-sensitive transcriptional activator SoxR WFL_21535
G ZNTR
(NRULE_0330)
Zinc-responsive transcriptional regulator ZntR WFL_17385
H NIKR
(NRULE_0331)
Nickel-responsive transcriptional regulator NikR WFL_18280
I ISCR
(NRULE_0332)
Rrf2 family transcriptional regulator IscR WFL_13500
Molybdate transport (ABC transporter) (NFUNC_0097)
必須 A MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding protein WFL_20815 WFL_21385 WFL_12990 WFL_03965
任意 MODE
(NRULE_0323)
Putative molybdate-dependent transcriptional regulator WFL_03955
MODB
(NRULE_0325)
Molybdate ABC transporter permease protein WFL_03970
MODC
(NRULE_0326)
Molybdate ABC transporter ATP-binding protein WFL_03975
(R)-pantothenate biosynthesis (NFUNC_0030)
必須 A PAND
(NRULE_0115)
Aspartate 1-decarboxylase WFL_00630
PANB
(NRULE_0116)
3-methyl-2-oxobutanoate hydroxymethyltransferase WFL_00645
PANE
(NRULE_0117)
2-dehydropantoate 2-reductase WFL_02445
PANC
(NRULE_0118)
Pantothenate synthetase WFL_00640
Phenol degradation (NFUNC_0028)
必須 B PHEA1
(NRULE_0083)
Aromatic ring hydroxylase WFL_22920
C PHEA2
(NRULE_0084)
Aromatic ring hydroxylase WFL_02090
任意 FDR2
(NRULE_0057)
Ferredoxin reductase WFL_13555
FDR1
(NRULE_0032)
Oxygenase electron transfer component WFL_04775 WFL_07455 WFL_09690
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxin WFL_13535 WFL_09685 WFL_13545
FADR1
(NRULE_0101)
NADH-dependent flavin reductase WFL_07780 WFL_22915 WFL_05450
Phytic acid hydrolysis (NFUNC_0085)
必須 B APPA
(NRULE_0259)
Periplasmic AppA protein WFL_05315
Polymyxin resistance (NFUNC_0036)
必須 A ARNA
(NRULE_0132)
Bifunctional polymyxin resistance protein ArnA WFL_11970
ARNB
(NRULE_0133)
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase WFL_11960
ARNC
(NRULE_0134)
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase WFL_11965
ARND
(NRULE_0135)
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD WFL_11975
ARNE
(NRULE_0136)
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE WFL_11985
ARNF
(NRULE_0137)
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF WFL_11990
ARNT
(NRULE_0138)
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase WFL_11980
Riboflavin biosynthesis (NFUNC_0058)
必須 A RIBB
(NRULE_0200)
3,4-dihydroxy-2-butanone 4-phosphate synthase WFL_16170
RIBA
(NRULE_0201)
GTP cyclohydrolase-2 WFL_06680
RIBD
(NRULE_0202)
Riboflavin biosynthesis protein RibD WFL_02390
RIBH
(NRULE_0203)
6,7-dimethyl-8-ribityllumazine synthase WFL_02395
RIBE
(NRULE_0204)
Riboflavin synthase WFL_08970
任意 RIBF
(NRULE_0205)
Riboflavin biosynthesis protein RibF WFL_00125
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate) (NFUNC_0031)
必須 A TPS
(NRULE_0119)
Trehalose-phosphate synthase WFL_10160
TPP
(NRULE_0120)
Trehalose-6-phosphate phosphatase WFL_10165
Uptake of osmoprotectant (NFUNC_0061)
必須 A OPUAC
(NRULE_0213)
Osmoprotectant ABC transporter substrate-binding protein WFL_14055
OPUAB
(NRULE_0214)
Osmoprotectant ABC transporter permease protein WFL_14050
OPUAA
(NRULE_0215)
Osmoprotectant ABC transporter ATP-binding protein WFL_14045
C BCCT
(NRULE_0220)
BCCT family transporter WFL_09680 WFL_00200 WFL_01905
D PROP
(NRULE_0221)
Osmoprotectant transporter WFL_21750
E OPUE
(NRULE_0222)
Sodium/proline symporter WFL_05495
Vitamin B6 biosynthesis (PdxA/PdxJ pathway) (NFUNC_0060)
必須 A EPD
(NRULE_0208)
D-erythrose-4-phosphate dehydrogenase WFL_15535
PDXB
(NRULE_0209)
Erythronate-4-phosphate dehydrogenase WFL_12285
SERC
(NRULE_0210)
Phosphoserine aminotransferase WFL_04945
PDXA
(NRULE_0211)
4-hydroxythreonine-4-phosphate dehydrogenase WFL_00260
PDXJ
(NRULE_0212)
Pyridoxine 5'-phosphate synthase WFL_13665