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遺伝子 : Acetoacetyl-CoA reductase (PHAB)

遺伝子情報

ID NRULE_0011
遺伝子ID PHAB
作成日 2012/07/10
タンパク質名
Protein name
Full
Acetoacetyl-CoA reductase
EC
EC 1.1.1.36
遺伝子名 該当データなし
遺伝子条件 TIGRFAMs; TIGR01829; hit=1
参照
Gene Ontology
GO
GO:0005737, C:cytoplasm, IEA:UniProtKB-SubCell
GO:0018454, F:acetoacetyl-CoA reductase activity, IEA:EC
GO:0042619, P:poly-hydroxybutyrate biosynthetic process, IEA:UniProtKB-KW
Phylogenomic databases
KO
K00023, -
Enzyme and pathway databases
UniPathway
UPA00917, -
Family and domain databases
InterPro
IPR011283, Acetoacetyl-CoA_reductase
IPR002198, DH_sc/Rdtase_SDR
IPR002347, Glc/ribitol_DH
IPR016040, NAD(P)-bd_dom
IPR020904, Sc_DH/Rdtase_CS
Pfam
PF00106, adh_short, 1
PRINTS
PR00081, GDHRDH
PR00080, SDRFAMILY
TIGRFAMs
TIGR01829, AcAcCoA_reduct, 1
PROSITE
PS00061, ADH_SHORT, 1
配列の特徴
P45375 Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum).
NP_BIND7 - 31NADP (By similarity).
ACT_SITE153Proton acceptor (By similarity).
BINDING140Substrate (By similarity).
P14697 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha).
NP_BIND8 - 32NADP (By similarity).
ACT_SITE153Proton acceptor (By similarity).
BINDING140Substrate (By similarity).
注釈
Catalytic activity
(R)-3-hydroxyacyl-CoA + NADP(+) = 3-oxoacyl- CoA + NADPH
Pathway
Biopolymer metabolism; poly-(R)-3-hydroxybutanoate biosynthesis
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family
参考文献
P45375 Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum).
1396692
Cloning and nucleotide sequences of genes relevant for biosynthesis of poly(3-hydroxybutyric acid) in Chromatium vinosum strain D. (Eur J Biochem. 1992)
P14697 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha).
2670935
Poly-beta-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding beta-ketothiolase and acetoacetyl-CoA reductase. (J Biol Chem. 1989)



関与する機能

機能名
Bioplastic synthesis

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acidiphilium multivorum100883ACMV_30830acetoacetyl-CoA reductase
Azorhizobium caulinodans14845AZC_0305acetoacetyl-CoA reductase
Bacillus cereus15305BC_1317Acetoacetyl-CoA reductase
Bacillus mycoides101228bmyco0001_116603-oxoacyl-[acyl-carrier-protein] reductase
Bacillus pseudomycoides101232bpmyx0001_118003-oxoacyl-[acyl-carrier-protein] reductase
Bacillus thuringiensis101235bthur0008_119503-oxoacyl-[acyl-carrier-protein] reductase
Bradyrhizobium diazoefficiens14792bll0225acetoacetyl CoA reductase
blr3725acetoacetyl CoA reductase
Brevundimonas diminuta12697BDIM_03840acetoacetyl-CoA reductase
Brevundimonas subvibrioides16000Bresu_0821acetoacetyl-CoA reductase
Caulobacter segnis15250Cseg_0393acetoacetyl-CoA reductase
Chromobacterium violaceum12614CV_2364acetoacetyl-CoA reductase
Cupriavidus metallidurans102507Rmet_13333-oxoacyl-(acyl-carrier-protein) reductase (protein belongs to CMGI-2)
Rmet_1358Acetoacetyl-CoA reductase
Rmet_5123acetoacetyl-CoA reductase
Flexibacter litoralis15988Fleli_31863-oxoacyl-(acyl-carrier-protein) reductase
Frateuria aurantia3245Fraau_0742acetoacetyl-CoA reductase
Halomonas elongata15536HELO_3876acetoacetyl-CoA reductase
Hylemonella gracilis14920HGR_130893-ketoacyl-(acyl-carrier-protein) reductase
Hyphomonas neptunium14232HNE_3404acetoacetyl-CoA reductase
Kyrpidia tusciae15312Btus_15903-oxoacyl-(acyl-carrier-protein) reductase
Labrenzia aggregata16684SIAM614_26693Short-chain dehydrogenase/reductase
Magnetospirillum gryphiswaldense15271MGR_4242Acetoacetyl-CoA reductase
Magnetospirillum magnetotacticum15272Magn03010791COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Methylobacterium radiotolerans15690Mrad2831_5119acetoacetyl-CoA reductase
Microscilla marina16560M23134_00128acetoacetyl-CoA reductase
Phaeobacter gallaeciensis16654PGA1_c03390acetoacetyl-CoA reductase PhaB
Photobacterium damselae subsp. damselae corrig.15633VDA_002425acetoacetyl-CoA reductase
Rhizobium etli15573RHE_CH04019acetoacetyl-CoA reductase protein
Rhizobium sp.101917NGR_c32710acetoacetyl-CoA reductase
Rhizobium tropici15247RTCIAT899_CH18010acetoacetyl-CoA reductase
Rhodobacter capsulatus16581RCAP_rcc03179acetoacetyl-CoA reductase
Rhodobacter sphaeroides12203RSP_07473-oxoacyl-[acyl-carrier-protein] reductase
Roseobacter denitrificans15277RD1_3395acetoacetyl-CoA reductase, putative
Roseobacter litoralis15278RLO149_c027530acetoacetyl-CoA reductase PhaB
Sphingobium japonicum101211SJA_C1-10300acetoacetyl-CoA reductase
Sphingobium sp.103272SLG_38730acetoacetyl-CoA reductase
Sphingomonas echinoides15742SechA1_010100013831acetoacetyl-CoA reductase
Sphingomonas wittichii105917Swit_45993-oxoacyl-[acyl-carrier-protein] reductase
Starkeya novella14993Snov_2736acetoacetyl-CoA reductase
Thauera linaloolentis102519C666_02960acetoacetyl-CoA reductase
C666_02965acetoacetyl-CoA reductase
Thermodesulfobacterium communeHL41_057553-oxoacyl-ACP synthase
Vibrio alginolyticus15630N646_3908acetoacetyl-CoA reductase
Vibrio ichthyoenteri15847VII00023_20232acetoacetyl-CoA reductase
Vibrio metschnikovii103153VIB_001812acetoacetyl-CoA reductase
Vibrio orientalis15638VIOR3934_13857acetoacetyl-CoA reductase
Vibrio tubiashii15644VITU9109_01907acetoacetyl-CoA reductase
Vibrio vulnificus15645B736_159203-ketoacyl-ACP reductase