| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
B1GSN3_9ACTO (B1GSN3) |
|
|
3e-41 |
171 |
100% |
|
- Product
- BenC protein
- Gene
- benC
- Organism
- Streptomyces sp. A2991200
|
1uniprot[Pubmed] 17439117 Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007] |
|
2
|
Q2MGC9_STRGR (Q2MGC9) |
|
|
5e-13 |
77.8 |
51% |
|
- Product
- ACP
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 16305230 Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005] |
|
3
|
F4FBT5_VERMA (F4FBT5) |
|
|
3e-12 |
75.5 |
49% |
|
- Product
- Putative uncharacterized protein
- Gene
- VAB18032_18165
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
4
|
E2EKK1_9ACTO (E2EKK1) |
|
|
4e-11 |
71.6 |
48% |
|
- Product
- Acyl carrier protein
- Gene
- sanH
- Organism
- Streptomyces sp. SANK 61196
|
1uniprot[Pubmed] 20550125 Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010] |
|
5
|
C7N0D3_SACVD (C7N0D3) |
|
|
1e-09 |
66.2 |
38% |
|
- Product
- Acyl carrier protein
- Gene
- Svir_33710
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
6
|
D2AY46_STRRD (D2AY46) |
|
|
3e-09 |
65.5 |
42% |
|
- Product
- Putative uncharacterized protein
- Gene
- Sros_4152
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
8
|
D2SZ01_MICEC (D2SZ01) |
|
|
5e-09 |
64.7 |
40% |
|
- Product
- Acyl carrier protein
- Gene
-
- Organism
- Micromonospora echinospora subsp. challisensis
|
1uniprot[Pubmed] 19680283 TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009] |
|
11
|
D7BZR1_STRBB (D7BZR1) |
|
|
3e-08 |
62 |
41% |
|
- Product
- Phosphopantetheine-binding protein
- Gene
- SBI_06846
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
12
|
A8KQY0_9ACTO (A8KQY0) |
|
|
3e-08 |
62 |
37% |
|
- Product
- Acyl carrier protein
- Gene
- elmM
- Organism
- Streptomyces olivaceus
|
1uniprot[Pubmed] 18310024 Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008] |
|
15
|
Q9K3G8_STRCO (Q9K3G8) |
|
|
2e-07 |
58.9 |
39% |
|
- Product
- Putative acyl carrier protein
- Gene
- SCO1272
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
17
|
Q54283_SACHI (Q54283) |
|
|
3e-07 |
58.5 |
42% |
|
- Product
- Acyl carrier protein
- Gene
-
- Organism
- Saccharopolyspora hirsuta
|
1uniprot[Pubmed] 8341260 [Medline] 93341453 Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993] |
|
18
|
Q9F6D5_9ACTO (Q9F6D5) |
|
|
3e-07 |
58.5 |
42% |
|
- Product
- Acyl carrier protein
- Gene
- zhuG
- Organism
- Streptomyces sp. R1128
|
1uniprot[Pubmed] 10931852 [Medline] 20517899 Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000] |
|
21
|
Q9ZAU0_STRPE (Q9ZAU0) |
|
|
6e-07 |
57.8 |
40% |
|
- Product
- Daunorubicin acyl carrier protein
- Gene
- dpsG
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 9864344 [Medline] 99084971 Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene.(J. Bacteriol.) [1999] |
|
22
|
C7PWQ7_CATAD (C7PWQ7) |
|
|
6e-07 |
57.8 |
40% |
|
- Product
- Phosphopantetheine-binding
- Gene
- Caci_6487
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
23
|
O68916_9ACTO (O68916) |
|
|
6e-07 |
57.8 |
43% |
|
- Product
- Acyl carrier protein
- Gene
- frnJ
- Organism
- Streptomyces roseofulvus
|
1uniprot[Pubmed] 8181754 [Medline] 94237486 Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994] |
|
25
|
Q9FCM6_STRAT (Q9FCM6) |
|
|
6e-07 |
57.8 |
40% |
|
- Product
- Putative Acyl carrier protein
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 11700358 [Medline] 21557167 A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001] |
|
26
|
Q9XDZ8_9ACTO (Q9XDZ8) |
|
|
7e-07 |
57.4 |
40% |
|
- Product
- Polyketide synthase
- Gene
-
- Organism
- Actinomadura verrucosospora
|
1uniprot[Pubmed] 10347064 [Medline] 99278093 Development of a self-cloning system for Actinomadura verrucosospora and identification of polyketide synthase genes essential for production of the angucyclic antibiotic pradimicin.(Appl. Environ. Microbiol.) [1999] |
|
27
|
B6SEF3_9ACTO (B6SEF3) |
|
|
9e-07 |
57 |
38% |
|
- Product
- AlnN acyl carrier protein
- Gene
- alnN
- Organism
- Streptomyces sp. CM020
|
1uniprot[Pubmed] 18940666 Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008] |
|
28
|
O32453_9ACTO (O32453) |
|
|
1e-06 |
56.6 |
47% |
|
- Product
- ORF 3
PdmC
- Gene
- pdmC
- Organism
- Actinomadura hibisca
|
1uniprot[Pubmed] 9339544 [Medline] 97480928 Cloning and nucleotide sequence of the putative polyketide synthase genes for pradimicin biosynthesis from Actinomadura hibisca.(Biosci. Biotechnol. Biochem.) [1997] |
|
29
|
Q53878_STRS5 (Q53878) |
|
|
2e-06 |
56.2 |
39% |
|
- Product
- Acyl carrier protein
- Gene
- dauA(g)
- Organism
- Streptomyces sp. (strain C5)
|
1uniprot[Pubmed] 8655529 [Medline] 96236066 Cloning, sequencing, and analysis of aklaviketone reductase from Streptomyces sp. strain C5.(J. Bacteriol.) [1996] |
|
30
|
D9UBR7_STRPR (D9UBR7) |
|
|
2e-06 |
56.2 |
40% |
|
- Product
- Putative acyl carrier protein
- Gene
- cpp17
- Organism
- Streptomyces pristinaespiralis
|
1uniprot[Pubmed] 21342465 Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011] |
|
32
|
B0LJ41_9ACTO (B0LJ41) |
|
|
4e-06 |
54.7 |
33% |
|
- Product
- Lcz24
- Gene
- lcz24
- Organism
- Streptomyces sanglieri
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
34
|
Q9F6C8_9ACTO (Q9F6C8) |
|
|
5e-06 |
54.7 |
41% |
|
- Product
- Acyl carrier protein
- Gene
- zhuN
- Organism
- Streptomyces sp. R1128
|
1uniprot[Pubmed] 10931852 [Medline] 20517899 Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000] |
|
35
|
B6SEE9_9ACTO (B6SEE9) |
|
|
5e-06 |
54.7 |
33% |
|
- Product
- AlnJ starter unit acyl carrier protein
- Gene
- alnJ
- Organism
- Streptomyces sp. CM020
|
1uniprot[Pubmed] 18940666 Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008] |
|
37
|
Q9X463_STRAE (Q9X463) |
|
|
7e-06 |
54.3 |
35% |
|
- Product
- Acyl carrier protein
- Gene
- ncnC
- Organism
- Streptomyces arenae
|
1uniprot[Pubmed] 10206788 [Medline] 99217421 Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999] |
|
38
|
Q9KHK4_9ACTO (Q9KHK4) |
|
|
9e-06 |
53.9 |
39% |
|
- Product
- Putative acyl carrier protein EncC
- Gene
- encC
- Organism
- Streptomyces maritimus
|
1uniprot Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000] | 2uniprot[Pubmed] 11137817 [Medline] 20579517 Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000] | 3uniprot[Pubmed] 11948863 [Medline] 21942282 A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001] | [pubmed all]
|
40
|
ACPX_STRCO (Q02054) |
|
|
1e-05 |
53.5 |
35% |
|
- Product
- Actinorhodin polyketide synthase acyl carrier protein
actI ORF3
- Gene
- SCO5089
SCBAC28G1.15
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 1527048 [Medline] 92406871 Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992] | 2uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | 3uniprot[Pubmed] 9166770 [Medline] 97309355 Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).(Biochemistry) [1997] | [pubmed all]
|
41
|
C4NYK1_9ACTO (C4NYK1) |
|
|
1e-05 |
53.5 |
39% |
|
- Product
- SaqC
- Gene
- saqC
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
42
|
Q54996_9ACTO (Q54996) |
|
|
1e-05 |
53.1 |
40% |
|
- Product
- Acyl carrier protein
- Gene
- frnN
- Organism
- Streptomyces roseofulvus
|
1uniprot[Pubmed] 8181754 [Medline] 94237486 Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994] | 2uniprot[Pubmed] 12705828 [Medline] 22592266 Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein.(Biochemistry) [2003] | [pubmed all]
|
44
|
D1A6T5_THECD (D1A6T5) |
|
|
2e-05 |
52.8 |
38% |
|
- Product
- Phosphopantetheine-binding protein
- Gene
- Tcur_2794
- Organism
- Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
|
1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011] |
|
45
|
D2XDY1_9PSEU (D2XDY1) |
|
|
2e-05 |
52.4 |
35% |
|
- Product
- AzicC
- Gene
- azicC
- Organism
- Kibdelosporangium sp. MJ126-NF4
|
1uniprot[Pubmed] 19928906 Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009] |
|
46
|
B0LJ07_9ACTO (B0LJ07) |
|
|
2e-05 |
52.4 |
33% |
|
- Product
- Lct24
- Gene
- lct24
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
47
|
E5KJA4_STRCX (E5KJA4) |
|
|
4e-05 |
51.6 |
37% |
|
- Product
- TunK
- Gene
- tunK
- Organism
- Streptomyces chartreusis
|
1uniprot Dissecting tunicamycin biosynthesis by genome mining: cloning and heterologous expression of a minimal gene cluster.(Chem Sci) [2010] |
|
48
|
D6MSY3_9ACTO (D6MSY3) |
|
|
7e-05 |
50.8 |
33% |
|
- Product
- SsfC
- Gene
- ssfC
- Organism
- Streptomyces sp. SF2575
|
1uniprot[Pubmed] 19908837 Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009] |
|
49
|
D7RFJ7_AMYOR (D7RFJ7) |
|
|
7e-05 |
50.8 |
35% |
|
- Product
- Putative acyl carrier protein
- Gene
- bexC
- Organism
- Amycolatopsis orientalis subsp. vinearia
|
1uniprot[Pubmed] 20443562 A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010] |
|
52
|
Q0MRN3_9ACTO (Q0MRN3) |
|
|
9e-05 |
50.4 |
37% |
|
- Product
- Putative acyl carrier protein
- Gene
-
- Organism
- Streptomyces toxytricini
|
1uniprot[Pubmed] 17205043 Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.(J. Microbiol.) [2006] |
|
54
|
Q8KSY8_9ACTO (Q8KSY8) |
|
|
0.0001 |
50.1 |
36% |
|
- Product
- Putative acyl carrier protein GrhC
- Gene
- grhC
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
55
|
Q53673_STRAA (Q53673) |
|
|
0.0001 |
50.1 |
38% |
|
- Product
- Acyl carrier protein
- Gene
- mtmS
- Organism
- Streptomyces argillaceus
|
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] | 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] | 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] | 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] | 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] | 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] | 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] | 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] | 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] | 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] | 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] | 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] | 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] | 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] | 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] | 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] | 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] | 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] | 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] | 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] | [pubmed all]
|
57
|
Q2PA09_9ACTO (Q2PA09) |
|
|
0.0001 |
49.7 |
40% |
|
- Product
- Acyl carrier protein
- Gene
- stfS
- Organism
- Streptomyces steffisburgensis
|
1uniprot[Pubmed] 16751529 Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006] |
|
58
|
B5GL46_STRCL (B5GL46) |
|
|
0.0002 |
49.7 |
43% |
|
- Product
- Polyketide synthase
Putative uncharacterized protein
- Gene
- SCLAV_4277
SSCG_00070
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
59
|
ACPX_STRVN (P12885) |
|
|
0.0002 |
49.7 |
37% |
|
- Product
- Granaticin polyketide synthase acyl carrier protein
- Gene
- gra-orf3
- Organism
- Streptomyces violaceoruber
|
1uniprot[Pubmed] 2583128 [Medline] 90060034 Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989] | 2uniprot[Pubmed] 9831526 [Medline] 99051446 The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998] | 3uniprot[Pubmed] 7476861 [Medline] 96027933 Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995] | [pubmed all]
|
61
|
A8P8G0_BRUMA (A8P8G0) |
|
|
0.0002 |
49.7 |
46% |
|
- Product
- Acyl carrier protein
- Gene
- Bm1_19045
- Organism
- Brugia malayi
Filarial nematode worm
|
1uniprot[Pubmed] 17885136 Draft genome of the filarial nematode parasite Brugia malayi.(Science) [2007] |
|
63
|
Q4R0M0_STRCX (Q4R0M0) |
|
|
0.0002 |
48.9 |
35% |
|
- Product
- ChaC protein
- Gene
- chaC
- Organism
- Streptomyces chartreusis
|
1uniprot[Pubmed] 15911378 Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005] |
|
67
|
Q54497_STRNO (Q54497) |
|
|
0.0004 |
48.1 |
35% |
|
- Product
- Snoa3
- Gene
- snoa3
- Organism
- Streptomyces nogalater
|
1uniprot[Pubmed] 8668120 [Medline] 96242142 A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996] | 2uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] | 3uniprot[Pubmed] 8760909 [Medline] 96349102 Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996] | [pubmed all]
|
68
|
ACPX_STRGA (P12884) |
|
|
0.0005 |
48.1 |
34% |
|
- Product
- Tetracenomycin C polyketide synthase acyl carrier protein
- Gene
- tcmM
- Organism
- Streptomyces glaucescens
|
1uniprot[Pubmed] 2684656 [Medline] 90060035 Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.(EMBO J.) [1989] | 2uniprot[Pubmed] 1548230 [Medline] 92193265 Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.(J. Bacteriol.) [1992] | [pubmed all]
|
69
|
ACPX_STRCM (P41174) |
|
|
0.0005 |
48.1 |
38% |
|
- Product
- Monensin polyketide synthase acyl carrier protein
- Gene
-
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 1508151 [Medline] 92374994 Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992] |
|
70
|
Q2J5J5_FRASC (Q2J5J5) |
|
|
0.0006 |
47.8 |
38% |
|
- Product
- Phosphopantetheine-binding
- Gene
- Francci3_4099
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
72
|
Q3K404_STRA1 (Q3K404) |
|
|
0.0007 |
47.4 |
37% |
|
- Product
- Acyl carrier protein 1
- Gene
- acpP1
SAK_0056
- Organism
- Streptococcus agalactiae serotype Ia
|
1uniprot[Pubmed] 16172379 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
73
|
Q3D3V8_STRAG (Q3D3V8) |
|
|
0.0007 |
47.4 |
37% |
|
- Product
- Acyl carrier protein 2
- Gene
- acpP2
SAI_0011
- Organism
- Streptococcus agalactiae H36B
|
1uniprot[Pubmed] 16172379 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
74
|
Q67G32_9ACTO (Q67G32) |
|
|
0.0008 |
47.4 |
33% |
|
- Product
- Putative bifunctional cyclase dehydratase and ACP fusion
- Gene
-
- Organism
- Streptomyces griseoruber
|
1uniprot[Pubmed] 15271354 The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004] |
|
75
|
Q8E7X3_STRA3 (Q8E7X3) |
|
|
0.0009 |
47.4 |
35% |
|
- Product
- Acyl carrier protein 1
- Gene
- acpP1
gbs0022
- Organism
- Streptococcus agalactiae serotype III
|
1uniprot[Pubmed] 12354221 [Medline] 22242508 Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease.(Mol. Microbiol.) [2002] |
|
76
|
Q8E2G5_STRA5 (Q8E2G5) |
|
|
0.0009 |
47.4 |
35% |
|
- Product
- Acyl carrier protein 1
- Gene
- acpP-1
acpP1 SAG0023
- Organism
- Streptococcus agalactiae serotype V
|
1uniprot[Pubmed] 12200547 [Medline] 22222988 Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae.(Proc. Natl. Acad. Sci. U.S.A.) [2002] |
|
77
|
Q3DSB7_STRAG (Q3DSB7) |
|
|
0.0009 |
47.4 |
35% |
|
- Product
- Acyl carrier protein 1
- Gene
- acpP1
SAJ_0077
- Organism
- Streptococcus agalactiae 18RS21
|
1uniprot[Pubmed] 16172379 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
78
|
Q3DJT4_STRAG (Q3DJT4) |
|
|
0.0009 |
47.4 |
35% |
|
- Product
- Acyl carrier protein 2
- Gene
- acpP2
SAL_0023
- Organism
- Streptococcus agalactiae 515
|
1uniprot[Pubmed] 16172379 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
79
|
Q3D8G2_STRAG (Q3D8G2) |
|
|
0.0009 |
47.4 |
35% |
|
- Product
- Acyl carrier protein 2
- Gene
- acpP2
SAN_0031
- Organism
- Streptococcus agalactiae COH1
|
1uniprot[Pubmed] 16172379 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|