BLAST table : Tatmc_00080

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 A4KCE4_9ACTO
(A4KCE4)		 
[query] 1 - 9648 (9648)
[subject] 1 - 9648 (9648)
 0.0 18850   100% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
2
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 117 - 9648 (9648)
[subject] 1 - 9528 (9528)
(3 hsp)		 0.0 17970   99% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
3
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 552 - 9607 (9648)
[subject] 3 - 9270 (10827)
(17 hsp)		 0.0 10400   63% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
4
 Q82QT4_STRAW
(Q82QT4)		 
[query] 2652 - 8902 (9648)
[subject] 938 - 7289 (7746)
(23 hsp)		 0.0 5207   50% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
5
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 2757 - 8902 (9648)
[subject] 34 - 6378 (6831)
(15 hsp)		 0.0 5187   50% ScnS1 scnS1 Streptomyces chattanoogensis
6
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 983 - 7563 (9648)
[subject] 1616 - 8224 (8301)
(17 hsp)		 0.0 5133   50% Type I polyketide synthase sfaH Streptomyces flaveolus
7
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 2757 - 8907 (9648)
[subject] 34 - 6349 (6797)
(15 hsp)		 0.0 5130   50% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
8
 D9T6W4_MICAI
(D9T6W4)		 
[query] 2755 - 8902 (9648)
[subject] 33 - 6451 (9936)
(27 hsp)		 0.0 5066   50% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
9
 E8S0C5_MICSL
(E8S0C5)		 
[query] 2755 - 8902 (9648)
[subject] 33 - 6451 (9937)
(27 hsp)		 0.0 5053   50% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
10
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 984 - 6741 (9648)
[subject] 3143 - 9198 (10873)
(33 hsp)		 0.0 4919   50% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
11
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 5885 - 9606 (9648)
[subject] 30 - 3803 (5770)
(16 hsp)		 0.0 4628   67% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
12
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 991 - 4224 (9648)
[subject] 4023 - 7302 (7620)
(25 hsp)		 0.0 4326   72% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
13
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 4253 - 9625 (9648)
[subject] 31 - 5584 (10876)
(26 hsp)		 0.0 4310   51% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
14
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 991 - 4224 (9648)
[subject] 3980 - 7258 (7576)
(25 hsp)		 0.0 4285   71% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
15
 E0L044_STRVO
(E0L044)		 
[query] 3784 - 8930 (9648)
[subject] 1378 - 6798 (7224)
(22 hsp)		 0.0 4208   48% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
16
 D7BRD4_STRBB
(D7BRD4)		 
[query] 3781 - 8916 (9648)
[subject] 4122 - 9506 (9950)
(25 hsp)		 0.0 4112   50% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
17
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 3902 - 8902 (9648)
[subject] 5220 - 10453 (10917)
(26 hsp)		 0.0 4097   49% AmphC amphC Streptomyces nodosus
18
 Q93H87_STRAW
(Q93H87)		 
[query] 2652 - 7559 (9648)
[subject] 938 - 5959 (6048)
(20 hsp)		 0.0 4096   49% Modular polyketide synthase pteA1 Streptomyces avermitilis
19
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 4252 - 9596 (9648)
[subject] 29 - 5185 (6260)
(20 hsp)		 0.0 4059   48% Polyketide synthase rapC Streptomyces hygroscopicus
20
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 4253 - 9605 (9648)
[subject] 29 - 5240 (10223)
(24 hsp)		 0.0 4007   47% Polyketide synthase rapB Streptomyces hygroscopicus
21
 Q52V53_9ACTO
(Q52V53)		 
[query] 2757 - 7567 (9648)
[subject] 34 - 5131 (5207)
(17 hsp)		 0.0 4002   49% Polyketide synthase type I Streptomyces aizunensis
22
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 4242 - 8880 (9648)
[subject] 3 - 4854 (4894)
(11 hsp)		 0.0 3977   50% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
23
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 983 - 5866 (9648)
[subject] 1736 - 6978 (7026)
(17 hsp)		 0.0 3966   48% Polyketide synthase pldAII Streptomyces platensis
24
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 3784 - 8902 (9648)
[subject] 1422 - 6665 (7110)
(15 hsp)		 0.0 3961   49% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
25
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 2387 - 5562 (9648)
[subject] 1703 - 4968 (5710)
(20 hsp)		 0.0 3953   66% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
26
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 3769 - 8915 (9648)
[subject] 1299 - 6587 (10625)
(28 hsp)		 0.0 3902   48% FscC fscC Streptomyces sp. FR-008
27
 A4X8L0_SALTO
(A4X8L0)		 
[query] 3800 - 8900 (9648)
[subject] 1453 - 6752 (7210)
(17 hsp)		 0.0 3880   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
28
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1083 - 5582 (9648)
[subject] 34 - 4659 (7102)
(21 hsp)		 0.0 3867   51% Polyketide synthase merB Streptomyces sp. NRRL 30748
29
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 2757 - 7567 (9648)
[subject] 34 - 5138 (5220)
(14 hsp)		 0.0 3854   48% Type I polyketide synthase hlsC Streptomyces halstedii
30
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 4263 - 8728 (9648)
[subject] 41 - 4661 (11096)
(36 hsp)		 0.0 3789   51% NysC nysC Streptomyces noursei
31
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4257 - 8903 (9648)
[subject] 34 - 4920 (5588)
(14 hsp)		 0.0 3756   48% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 4152 - 8906 (9648)
[subject] 914 - 5801 (6241)
(20 hsp)		 0.0 3752   48% Polyketide synthase KijS1 Actinomadura kijaniata
33
 A8M6C7_SALAI
(A8M6C7)		 
[query] 4257 - 8912 (9648)
[subject] 35 - 4821 (5255)
(13 hsp)		 0.0 3733   50% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
34
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 1083 - 5567 (9648)
[subject] 34 - 4714 (7178)
(21 hsp)		 0.0 3731   50% MerB merB Streptomyces violaceoniger
35
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4257 - 8902 (9648)
[subject] 34 - 4658 (5099)
(12 hsp)		 0.0 3719   49% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
36
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 4257 - 8902 (9648)
[subject] 35 - 4642 (5060)
(12 hsp)		 0.0 3697   49% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
37
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 4257 - 8902 (9648)
[subject] 35 - 4642 (5060)
(12 hsp)		 0.0 3694   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
38
 O52789_AMYMD
(O52789)		 
[query] 4257 - 8902 (9648)
[subject] 44 - 4651 (5069)
(12 hsp)		 0.0 3691   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
39
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2757 - 7046 (9648)
[subject] 34 - 4553 (7111)
(25 hsp)		 0.0 3685   51% Type I polyketide synthase hlsB Streptomyces halstedii
40
 Q52V46_9ACTO
(Q52V46)		 
[query] 2303 - 6748 (9648)
[subject] 1208 - 5886 (8147)
(28 hsp)		 0.0 3683   50% Polyketide synthase type I Streptomyces aizunensis
41
 Q52V52_9ACTO
(Q52V52)		 
[query] 4258 - 8729 (9648)
[subject] 35 - 4733 (5432)
(17 hsp)		 0.0 3660   49% Polyketide synthase type I Streptomyces aizunensis
42
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 2391 - 7215 (9648)
[subject] 9289 - 14421 (16990)
(43 hsp)		 0.0 3659   45% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
43
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 4228 - 8903 (9648)
[subject] 7 - 4739 (5176)
(13 hsp)		 0.0 3659   48% ObsB Saccharopolyspora spinosa
44
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 4257 - 8904 (9648)
[subject] 35 - 4887 (5339)
(14 hsp)		 0.0 3654   48% Polyketide synthase natB Streptomyces sp. CS
45
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 4165 - 8928 (9648)
[subject] 901 - 5625 (6078)
(17 hsp)		 0.0 3653   48% ObsA Saccharopolyspora spinosa
46
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4257 - 8894 (9648)
[subject] 39 - 4734 (5400)
(13 hsp)		 0.0 3649   50% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
47
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4256 - 8906 (9648)
[subject] 30 - 4866 (5321)
(13 hsp)		 0.0 3633   49% Polyketide synthase natC Streptomyces sp. CS
48
 E0KFI7_STRVO
(E0KFI7)		 
[query] 1075 - 5405 (9648)
[subject] 27 - 4483 (8538)
(27 hsp)		 0.0 3632   49% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
49
 D7C2B8_STRBB
(D7C2B8)		 
[query] 5569 - 9613 (9648)
[subject] 3278 - 7420 (7498)
(24 hsp)		 0.0 3591   51% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
50
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 1083 - 5125 (9648)
[subject] 34 - 4214 (9498)
(39 hsp)		 0.0 3580   52% ScnS2 scnS2 Streptomyces chattanoogensis
51
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1083 - 5116 (9648)
[subject] 34 - 4198 (9510)
(39 hsp)		 0.0 3555   52% AmphI amphI Streptomyces nodosus
52
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 4152 - 8908 (9648)
[subject] 918 - 5927 (6383)
(21 hsp)		 0.0 3547   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
53
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1083 - 5125 (9648)
[subject] 34 - 4221 (9507)
(38 hsp)		 0.0 3543   52% PimS2 protein pimS2 Streptomyces natalensis
54
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 2658 - 6744 (9648)
[subject] 952 - 5052 (5712)
(22 hsp)		 0.0 3526   52% Polyketide synthase merA Streptomyces sp. NRRL 30748
55
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 2658 - 6744 (9648)
[subject] 968 - 5054 (5721)
(22 hsp)		 0.0 3524   52% MerA merA Streptomyces violaceoniger
56
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 4184 - 8915 (9648)
[subject] 55 - 4872 (5260)
(13 hsp)		 0.0 3518   46% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
57
 E0KBI2_STRVO
(E0KBI2)		 
[query] 1079 - 5125 (9648)
[subject] 29 - 4204 (4930)
(19 hsp)		 0.0 3517   52% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
58
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 4255 - 8903 (9648)
[subject] 36 - 5067 (5532)
(11 hsp)		 0.0 3491   47% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
59
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1083 - 5121 (9648)
[subject] 34 - 4223 (9499)
(37 hsp)		 0.0 3484   52% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
60
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 4257 - 8902 (9648)
[subject] 34 - 4716 (5157)
(12 hsp)		 0.0 3479   48% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
61
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 3882 - 8915 (9648)
[subject] 2792 - 7519 (7938)
(20 hsp)		 0.0 3478   46% Polyketide synthase rapA Actinoplanes sp. N902-109
62
 E8WEN5_STRFA
(E8WEN5)		 
[query] 4257 - 8902 (9648)
[subject] 34 - 4715 (5156)
(12 hsp)		 0.0 3477   48% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
63
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 3884 - 8758 (9648)
[subject] 2429 - 7118 (7525)
(21 hsp)		 0.0 3472   47% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
64
 D7C2C3_STRBB
(D7C2C3)		 
[query] 1083 - 5123 (9648)
[subject] 34 - 4325 (4868)
(18 hsp)		 0.0 3466   50% Modular polyketide synthase pks3-4
SBI_00656		 Streptomyces bingchenggensis (strain BCW-1)
65
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1083 - 5116 (9648)
[subject] 34 - 4242 (9477)
(38 hsp)		 0.0 3458   51% NysI nysI Streptomyces noursei
66
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1083 - 5116 (9648)
[subject] 39 - 4220 (9550)
(38 hsp)		 0.0 3454   51% FscD fscD Streptomyces sp. FR-008
67
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 5750 - 9605 (9648)
[subject] 2445 - 6455 (6532)
(21 hsp)		 0.0 3443   52% Polyketide synthase pldAI Streptomyces platensis
68
 B5L6K8_MICCH
(B5L6K8)		 
[query] 4158 - 8900 (9648)
[subject] 921 - 5855 (6305)
(17 hsp)		 0.0 3441   45% Putative type I polyketide synthase Micromonospora chalcea
69
 B1W485_STRGG
(B1W485)		 
[query] 1083 - 5419 (9648)
[subject] 38 - 4487 (5136)
(15 hsp)		 0.0 3425   50% Putative type-I PKS pks1-1
SGR_6073		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
70
 F8JUL0_STRCT
(F8JUL0)		 
[query] 4150 - 8576 (9648)
[subject] 925 - 5432 (5950)
(21 hsp)		 0.0 3416   49% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
71
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 4152 - 8578 (9648)
[subject] 919 - 5577 (5582)
(17 hsp)		 0.0 3416   45% Polyketide synthase type I becA Streptomyces sp. DSM 21069
72
 F8JVX1_STRCT
(F8JVX1)		 
[query] 4159 - 8451 (9648)
[subject] 945 - 5407 (6125)
(20 hsp)		 0.0 3403   47% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
73
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 4225 - 8452 (9648)
[subject] 6 - 4510 (5232)
(17 hsp)		 0.0 3399   49% Type I polyketide synthase hlsF Streptomyces halstedii
74
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 4155 - 8226 (9648)
[subject] 883 - 4978 (5113)
(19 hsp)		 0.0 3397   49% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
75
 A8LUX2_SALAI
(A8LUX2)		 
[query] 981 - 5116 (9648)
[subject] 2560 - 6619 (7279)
(24 hsp)		 0.0 3358   50% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
76
 Q52V44_9ACTO
(Q52V44)		 
[query] 1075 - 5117 (9648)
[subject] 27 - 4225 (6751)
(22 hsp)		 0.0 3350   50% Polyketide synthase type I Streptomyces aizunensis
77
 E0L075_STRVO
(E0L075)		 
[query] 5890 - 9596 (9648)
[subject] 34 - 3850 (5786)
(20 hsp)		 0.0 3342   52% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
78
 D7P611_CHOCO
(D7P611)		 
[query] 5466 - 9604 (9648)
[subject] 1832 - 6162 (6255)
(21 hsp)		 0.0 3327   48% TugA tugA Chondromyces crocatus
79
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 3884 - 8900 (9648)
[subject] 2482 - 7348 (7655)
(20 hsp)		 0.0 3316   45% FkbB Streptomyces sp. MJM7001
80
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 3884 - 8900 (9648)
[subject] 2473 - 7339 (7646)
(20 hsp)		 0.0 3314   45% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
81
 E9LIP4_9ACTO
(E9LIP4)		 
[query] 2640 - 7563 (9648)
[subject] 441 - 5144 (5229)
(20 hsp)		 0.0 3294   46% Putative modular polyketide synthase tiaA1 Dactylosporangium aurantiacum subsp. hamdenensis
82
 E0KBI0_STRVO
(E0KBI0)		 
[query] 5888 - 9596 (9648)
[subject] 35 - 3854 (3955)
(13 hsp)		 0.0 3293   52% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
83
 D9T6W1_MICAI
(D9T6W1)		 
[query] 1083 - 5120 (9648)
[subject] 34 - 4183 (6415)
(24 hsp)		 0.0 3273   50% Beta-ketoacyl synthase Micau_2461 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
84
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1083 - 5125 (9648)
[subject] 38 - 4215 (4928)
(20 hsp)		 0.0 3266   49% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
85
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 4257 - 8443 (9648)
[subject] 36 - 4393 (5136)
(15 hsp)		 0.0 3260   46% Polyketide synthase tsnAII Streptomyces longisporoflavus
86
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 3941 - 8900 (9648)
[subject] 2494 - 7275 (7576)
(23 hsp)		 0.0 3251   45% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
87
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 4256 - 8914 (9648)
[subject] 35 - 4768 (6872)
(19 hsp)		 0.0 3243   45% Polyketide synthase KijS2 Actinomadura kijaniata
88
 A4FH85_SACEN
(A4FH85)		 
[query] 123 - 4237 (9648)
[subject] 17 - 4248 (4327)
(13 hsp)		 0.0 3234   49% Type I modular polyketide synthase SACE_4141 Saccharopolyspora erythraea (strain NRRL 23338)
89
 Q5VKQ3_SACER
(Q5VKQ3)		 
[query] 123 - 4237 (9648)
[subject] 17 - 4248 (4327)
(13 hsp)		 0.0 3234   49% Type I PKS pkeAI Saccharopolyspora erythraea
Streptomyces erythraeus
90
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 4253 - 8713 (9648)
[subject] 31 - 4568 (5066)
(14 hsp)		 0.0 3227   47% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
91
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 5890 - 9601 (9648)
[subject] 63 - 3753 (7488)
(20 hsp)		 0.0 3212   52% ObsC Saccharopolyspora spinosa
92
 F4F7F4_VERMA
(F4F7F4)		 
[query] 4161 - 8915 (9648)
[subject] 863 - 5407 (5781)
(19 hsp)		 0.0 3200   45% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
93
 B1W5P4_STRGG
(B1W5P4)		 
[query] 4253 - 8900 (9648)
[subject] 30 - 4408 (4843)
(14 hsp)		 0.0 3195   45% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
94
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 5885 - 9596 (9648)
[subject] 34 - 3825 (5644)
(16 hsp)		 0.0 3192   51% AmphJ amphJ Streptomyces nodosus
95
 A1YAM6_AMYOR
(A1YAM6)		 
[query] 5788 - 9610 (9648)
[subject] 33 - 3771 (3834)
(13 hsp)		 0.0 3162   51% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
96
 C9YYI2_STRSW
(C9YYI2)		 
[query] 5890 - 9596 (9648)
[subject] 38 - 3836 (3919)
(11 hsp)		 0.0 3159   51% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
97
 Q52V50_9ACTO
(Q52V50)		 
[query] 5890 - 9596 (9648)
[subject] 39 - 3906 (7510)
(19 hsp)		 0.0 3155   51% Polyketide synthase type I Streptomyces aizunensis
98
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 5553 - 9606 (9648)
[subject] 2922 - 6841 (8563)
(24 hsp)		 0.0 3151   48% Polyketide synthase rapA Streptomyces hygroscopicus
99
 D7CC07_STRBB
(D7CC07)		 
[query] 5777 - 9609 (9648)
[subject] 941 - 4907 (4979)
(13 hsp)		 0.0 3140   50% Putative type I polyketide synthase pks5-1
SBI_01381		 Streptomyces bingchenggensis (strain BCW-1)
100
 D3U9Y6_9ACTO
(D3U9Y6)		 
[query] 126 - 4224 (9648)
[subject] 36 - 4112 (4206)
(17 hsp)		 0.0 3138   48% Type I polyketide synthase sfaF Streptomyces flaveolus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 A4KCE4_9ACTO
(A4KCE4)		 
[query] 1 - 9648 (9648)
[subject] 1 - 9648 (9648)
 0.0 18850   100%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 117 - 9648 (9648)
[subject] 1 - 9528 (9528)
(3 hsp)		 0.0 17970   99%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
3
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 552 - 9607 (9648)
[subject] 3 - 9270 (10827)
(17 hsp)		 0.0 10400   63%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
4
 Q82QT4_STRAW
(Q82QT4)		 
[query] 2652 - 8902 (9648)
[subject] 938 - 7289 (7746)
(23 hsp)		 0.0 5207   50%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
5
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 2757 - 8902 (9648)
[subject] 34 - 6378 (6831)
(15 hsp)		 0.0 5187   50%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
6
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 983 - 7563 (9648)
[subject] 1616 - 8224 (8301)
(17 hsp)		 0.0 5133   50%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
7
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 2757 - 8907 (9648)
[subject] 34 - 6349 (6797)
(15 hsp)		 0.0 5130   50%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
11
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 5885 - 9606 (9648)
[subject] 30 - 3803 (5770)
(16 hsp)		 0.0 4628   67%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
12
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 991 - 4224 (9648)
[subject] 4023 - 7302 (7620)
(25 hsp)		 0.0 4326   72%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
13
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 4253 - 9625 (9648)
[subject] 31 - 5584 (10876)
(26 hsp)		 0.0 4310   51%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
14
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 991 - 4224 (9648)
[subject] 3980 - 7258 (7576)
(25 hsp)		 0.0 4285   71%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
16
 D7BRD4_STRBB
(D7BRD4)		 
[query] 3781 - 8916 (9648)
[subject] 4122 - 9506 (9950)
(25 hsp)		 0.0 4112   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
17
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 3902 - 8902 (9648)
[subject] 5220 - 10453 (10917)
(26 hsp)		 0.0 4097   49%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
18
 Q93H87_STRAW
(Q93H87)		 
[query] 2652 - 7559 (9648)
[subject] 938 - 5959 (6048)
(20 hsp)		 0.0 4096   49%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
19
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 4252 - 9596 (9648)
[subject] 29 - 5185 (6260)
(20 hsp)		 0.0 4059   48%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
20
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 4253 - 9605 (9648)
[subject] 29 - 5240 (10223)
(24 hsp)		 0.0 4007   47%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
21
 Q52V53_9ACTO
(Q52V53)		 
[query] 2757 - 7567 (9648)
[subject] 34 - 5131 (5207)
(17 hsp)		 0.0 4002   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
23
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 983 - 5866 (9648)
[subject] 1736 - 6978 (7026)
(17 hsp)		 0.0 3966   48%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
24
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 3784 - 8902 (9648)
[subject] 1422 - 6665 (7110)
(15 hsp)		 0.0 3961   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
25
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 2387 - 5562 (9648)
[subject] 1703 - 4968 (5710)
(20 hsp)		 0.0 3953   66%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
26
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 3769 - 8915 (9648)
[subject] 1299 - 6587 (10625)
(28 hsp)		 0.0 3902   48%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
28
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1083 - 5582 (9648)
[subject] 34 - 4659 (7102)
(21 hsp)		 0.0 3867   51%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
30
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 4263 - 8728 (9648)
[subject] 41 - 4661 (11096)
(36 hsp)		 0.0 3789   51%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
31
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4257 - 8903 (9648)
[subject] 34 - 4920 (5588)
(14 hsp)		 0.0 3756   48%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
32
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 4152 - 8906 (9648)
[subject] 914 - 5801 (6241)
(20 hsp)		 0.0 3752   48%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
34
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 1083 - 5567 (9648)
[subject] 34 - 4714 (7178)
(21 hsp)		 0.0 3731   50%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
35
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4257 - 8902 (9648)
[subject] 34 - 4658 (5099)
(12 hsp)		 0.0 3719   49%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
36
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 4257 - 8902 (9648)
[subject] 35 - 4642 (5060)
(12 hsp)		 0.0 3697   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
37
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 4257 - 8902 (9648)
[subject] 35 - 4642 (5060)
(12 hsp)		 0.0 3694   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
39
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2757 - 7046 (9648)
[subject] 34 - 4553 (7111)
(25 hsp)		 0.0 3685   51%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
40
 Q52V46_9ACTO
(Q52V46)		 
[query] 2303 - 6748 (9648)
[subject] 1208 - 5886 (8147)
(28 hsp)		 0.0 3683   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
41
 Q52V52_9ACTO
(Q52V52)		 
[query] 4258 - 8729 (9648)
[subject] 35 - 4733 (5432)
(17 hsp)		 0.0 3660   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
42
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 2391 - 7215 (9648)
[subject] 9289 - 14421 (16990)
(43 hsp)		 0.0 3659   45%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
43
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 4228 - 8903 (9648)
[subject] 7 - 4739 (5176)
(13 hsp)		 0.0 3659   48%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
44
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 4257 - 8904 (9648)
[subject] 35 - 4887 (5339)
(14 hsp)		 0.0 3654   48%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
45
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 4165 - 8928 (9648)
[subject] 901 - 5625 (6078)
(17 hsp)		 0.0 3653   48%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
46
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4257 - 8894 (9648)
[subject] 39 - 4734 (5400)
(13 hsp)		 0.0 3649   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
47
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4256 - 8906 (9648)
[subject] 30 - 4866 (5321)
(13 hsp)		 0.0 3633   49%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
49
 D7C2B8_STRBB
(D7C2B8)		 
[query] 5569 - 9613 (9648)
[subject] 3278 - 7420 (7498)
(24 hsp)		 0.0 3591   51%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
50
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 1083 - 5125 (9648)
[subject] 34 - 4214 (9498)
(39 hsp)		 0.0 3580   52%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
51
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1083 - 5116 (9648)
[subject] 34 - 4198 (9510)
(39 hsp)		 0.0 3555   52%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
52
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 4152 - 8908 (9648)
[subject] 918 - 5927 (6383)
(21 hsp)		 0.0 3547   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
53
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1083 - 5125 (9648)
[subject] 34 - 4221 (9507)
(38 hsp)		 0.0 3543   52%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
54
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 2658 - 6744 (9648)
[subject] 952 - 5052 (5712)
(22 hsp)		 0.0 3526   52%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
55
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 2658 - 6744 (9648)
[subject] 968 - 5054 (5721)
(22 hsp)		 0.0 3524   52%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
58
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 4255 - 8903 (9648)
[subject] 36 - 5067 (5532)
(11 hsp)		 0.0 3491   47%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
59
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1083 - 5121 (9648)
[subject] 34 - 4223 (9499)
(37 hsp)		 0.0 3484   52%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
63
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 3884 - 8758 (9648)
[subject] 2429 - 7118 (7525)
(21 hsp)		 0.0 3472   47%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
64
 D7C2C3_STRBB
(D7C2C3)		 
[query] 1083 - 5123 (9648)
[subject] 34 - 4325 (4868)
(18 hsp)		 0.0 3466   50%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
65
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1083 - 5116 (9648)
[subject] 34 - 4242 (9477)
(38 hsp)		 0.0 3458   51%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
66
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1083 - 5116 (9648)
[subject] 39 - 4220 (9550)
(38 hsp)		 0.0 3454   51%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
67
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 5750 - 9605 (9648)
[subject] 2445 - 6455 (6532)
(21 hsp)		 0.0 3443   52%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
68
 B5L6K8_MICCH
(B5L6K8)		 
[query] 4158 - 8900 (9648)
[subject] 921 - 5855 (6305)
(17 hsp)		 0.0 3441   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
69
 B1W485_STRGG
(B1W485)		 
[query] 1083 - 5419 (9648)
[subject] 38 - 4487 (5136)
(15 hsp)		 0.0 3425   50%
Product
Putative type-I PKS
Gene
pks1-1
SGR_6073
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
71
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 4152 - 8578 (9648)
[subject] 919 - 5577 (5582)
(17 hsp)		 0.0 3416   45%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
76
 Q52V44_9ACTO
(Q52V44)		 
[query] 1075 - 5117 (9648)
[subject] 27 - 4225 (6751)
(22 hsp)		 0.0 3350   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
78
 D7P611_CHOCO
(D7P611)		 
[query] 5466 - 9604 (9648)
[subject] 1832 - 6162 (6255)
(21 hsp)		 0.0 3327   48%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
80
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 3884 - 8900 (9648)
[subject] 2473 - 7339 (7646)
(20 hsp)		 0.0 3314   45%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
81
 E9LIP4_9ACTO
(E9LIP4)		 
[query] 2640 - 7563 (9648)
[subject] 441 - 5144 (5229)
(20 hsp)		 0.0 3294   46%
Product
Putative modular polyketide synthase
Gene
tiaA1
Organism
Dactylosporangium aurantiacum subsp. hamdenensis
1uniprot[Pubmed] 21186805
Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011]
84
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1083 - 5125 (9648)
[subject] 38 - 4215 (4928)
(20 hsp)		 0.0 3266   49%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
86
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 3941 - 8900 (9648)
[subject] 2494 - 7275 (7576)
(23 hsp)		 0.0 3251   45%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
87
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 4256 - 8914 (9648)
[subject] 35 - 4768 (6872)
(19 hsp)		 0.0 3243   45%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
88
 A4FH85_SACEN
(A4FH85)		 
[query] 123 - 4237 (9648)
[subject] 17 - 4248 (4327)
(13 hsp)		 0.0 3234   49%
Product
Type I modular polyketide synthase
Gene
SACE_4141
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
89
 Q5VKQ3_SACER
(Q5VKQ3)		 
[query] 123 - 4237 (9648)
[subject] 17 - 4248 (4327)
(13 hsp)		 0.0 3234   49%
Product
Type I PKS
Gene
pkeAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
90
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 4253 - 8713 (9648)
[subject] 31 - 4568 (5066)
(14 hsp)		 0.0 3227   47%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
91
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 5890 - 9601 (9648)
[subject] 63 - 3753 (7488)
(20 hsp)		 0.0 3212   52%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
92
 F4F7F4_VERMA
(F4F7F4)		 
[query] 4161 - 8915 (9648)
[subject] 863 - 5407 (5781)
(19 hsp)		 0.0 3200   45%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
93
 B1W5P4_STRGG
(B1W5P4)		 
[query] 4253 - 8900 (9648)
[subject] 30 - 4408 (4843)
(14 hsp)		 0.0 3195   45%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
94
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 5885 - 9596 (9648)
[subject] 34 - 3825 (5644)
(16 hsp)		 0.0 3192   51%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
95
 A1YAM6_AMYOR
(A1YAM6)		 
[query] 5788 - 9610 (9648)
[subject] 33 - 3771 (3834)
(13 hsp)		 0.0 3162   51%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
96
 C9YYI2_STRSW
(C9YYI2)		 
[query] 5890 - 9596 (9648)
[subject] 38 - 3836 (3919)
(11 hsp)		 0.0 3159   51%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
97
 Q52V50_9ACTO
(Q52V50)		 
[query] 5890 - 9596 (9648)
[subject] 39 - 3906 (7510)
(19 hsp)		 0.0 3155   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
98
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 5553 - 9606 (9648)
[subject] 2922 - 6841 (8563)
(24 hsp)		 0.0 3151   48%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
99
 D7CC07_STRBB
(D7CC07)		 
[query] 5777 - 9609 (9648)
[subject] 941 - 4907 (4979)
(13 hsp)		 0.0 3140   50%
Product
Putative type I polyketide synthase
Gene
pks5-1
SBI_01381
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
100
 D3U9Y6_9ACTO
(D3U9Y6)		 
[query] 126 - 4224 (9648)
[subject] 36 - 4112 (4206)
(17 hsp)		 0.0 3138   48%
Product
Type I polyketide synthase
Gene
sfaF
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]