BLAST table : Mith_00070

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q194R3_STRAA
(Q194R3)		 
[query] 1 - 331 (331)
[subject] 1 - 331 (331)
 0.0 671   100% dTDP-glucose 4,6-dehydratase mtmE Streptomyces argillaceus 4.2.1.46
2
 D9UBQ9_STRPR
(D9UBQ9)		 
[query] 3 - 322 (331)
[subject] 2 - 321 (335)
 1e-145 519   80% dTDP-glucose 4,6-dehydratase cpp25 Streptomyces pristinaespiralis 4.2.1.46
3
 B5HIU1_STRPR
(B5HIU1)		 
[query] 3 - 322 (331)
[subject] 2 - 321 (335)
 1e-145 519   80% dTDP-glucose 4,6-dehydratase SSDG_05078 Streptomyces pristinaespiralis ATCC 25486 4.2.1.46
4
 C5J046_STRPE
(C5J046)		 
[query] 3 - 322 (331)
[subject] 2 - 322 (328)
 1e-144 516   78% dTDP-glucose 4,6-dehydratase rmbB Streptomyces peucetius ATCC 27952 4.2.1.46
5
 B5H782_STRPR
(B5H782)		 
[query] 3 - 322 (331)
[subject] 2 - 322 (328)
 1e-143 513   79% dTDP-glucose 4,6-dehydratase SSDG_01263 Streptomyces pristinaespiralis ATCC 25486 4.2.1.46
6
 B5HXA7_9ACTO
(B5HXA7)		 
[query] 3 - 322 (331)
[subject] 2 - 322 (328)
 1e-143 513   79% dTDP-glucose 4,6-dehydratase SSEG_09375 Streptomyces sviceus ATCC 29083 4.2.1.46
7
 D1XFK5_9ACTO
(D1XFK5)		 
[query] 3 - 322 (331)
[subject] 2 - 322 (328)
 1e-142 510   79% dTDP-glucose 4,6-dehydratase SACTEDRAFT_1465 Streptomyces sp. SA3_actE 4.2.1.46
8
 D6A3M1_9ACTO
(D6A3M1)		 
[query] 4 - 322 (331)
[subject] 27 - 346 (353)
 1e-142 510   78% dTDP-glucose 4,6-dehydratase SSFG_04776 Streptomyces ghanaensis ATCC 14672 4.2.1.46
9
 D9Y1L8_9ACTO
(D9Y1L8)		 
[query] 6 - 324 (331)
[subject] 13 - 332 (337)
 1e-141 507   78% dTDP-glucose 4,6-dehydratase SSRG_04187 Streptomyces griseoflavus Tu4000 4.2.1.46
10
 D6MSX9_9ACTO
(D6MSX9)		 
[query] 3 - 324 (331)
[subject] 2 - 323 (327)
 1e-139 499   76% dTDP-glucose 4,6-dehydratase ssfS2 Streptomyces sp. SF2575 4.2.1.46
11
 Q7X2H7_9ACTO
(Q7X2H7)		 Jump to Gilvo_00130 
[query] 1 - 322 (331)
[subject] 1 - 325 (336)
 1e-136 488   73% dTDP-glucose 4,6-dehydratase gilE Streptomyces griseoflavus 4.2.1.46
12
 D9I0H4_9ACTO
(D9I0H4)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (326)
 1e-134 483   75% dTDP-glucose 4,6-dehydratase cpzDIII Streptomyces sp. MK730-62F2 4.2.1.46
13
 D1H0B0_9ACTO
(D1H0B0)		 
[query] 1 - 322 (331)
[subject] 1 - 322 (328)
 1e-134 482   74% dTDP-glucose 4,6-dehydratase chryE Streptomyces albaduncus 4.2.1.46
14
 D1GLU6_9ACTO
(D1GLU6)		 Jump to Strply_00180 
[query] 5 - 327 (331)
[subject] 2 - 327 (328)
 1e-133 479   74% dTDP-glucose 4,6-dehydratase slgS2 Streptomyces lydicus 4.2.1.46
15
 D9XDA8_STRVR
(D9XDA8)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (326)
 1e-133 478   75% dTDP-glucose 4,6-dehydratase SSQG_07273 Streptomyces viridochromogenes DSM 40736 4.2.1.46
16
 D1H0J1_9ACTO
(D1H0J1)		 
[query] 1 - 322 (331)
[subject] 1 - 322 (328)
 1e-133 478   73% dTDP-glucose 4,6-dehydratase ravE Streptomyces sp. C23201NS3 4.2.1.46
17
 D9W4I2_9ACTO
(D9W4I2)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (328)
 1e-132 476   72% dTDP-glucose 4,6-dehydratase SSNG_07062 Streptomyces sp. C 4.2.1.46
18
 D3Y166_STRPT
(D3Y166)		 
[query] 3 - 325 (331)
[subject] 41 - 363 (368)
 1e-127 459   70% dTDP-glucose 4,6-dehydratase strE Streptomyces platensis 4.2.1.46
19
 B1W376_STRGG
(B1W376)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (329)
 1e-127 459   70% dTDP-glucose 4,6-dehydratase strE
SGR_5929		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) 4.2.1.46
20
 Q53ID3_STRGR
(Q53ID3)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (329)
 1e-127 459   70% dTDP-glucose 4,6-dehydratase strE
SG7F10.19c		 Streptomyces griseus subsp. griseus 4.2.1.46
21
 Q7WTE5_9ACTO
(Q7WTE5)		 Jump to Nanch_00180 
[query] 5 - 325 (331)
[subject] 2 - 324 (331)
 1e-127 457   71% dTDP-glucose 4,6-dehydratase nanG2 Streptomyces nanchangensis 4.2.1.46
22
 E8S5H3_MICSL
(E8S5H3)		 
[query] 6 - 325 (331)
[subject] 3 - 330 (333)
 1e-126 457   71% dTDP-glucose 4,6-dehydratase ML5_1442 Micromonospora sp. (strain L5) 4.2.1.46
23
 D9TDA3_MICAI
(D9TDA3)		 
[query] 6 - 325 (331)
[subject] 3 - 330 (333)
 1e-126 456   70% dTDP-glucose 4,6-dehydratase Micau_1179 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) 4.2.1.46
24
 D7BSN0_STRBB
(D7BSN0)		 
[query] 5 - 325 (331)
[subject] 2 - 324 (331)
 1e-126 456   71% dTDP-glucose 4,6-dehydratase nanG2
SBI_08409		 Streptomyces bingchenggensis (strain BCW-1) 4.2.1.46
25
 O86866_STRGA
(O86866)		 
[query] 4 - 322 (331)
[subject] 3 - 320 (329)
 1e-126 456   71% dTDP-glucose 4,6-dehydratase strE Streptomyces glaucescens 4.2.1.46
26
 Q8KNI5_MICEC
(Q8KNI5)		 Jump to Calm_00120 
[query] 1 - 324 (331)
[subject] 1 - 326 (343)
 1e-126 455   70% dTDP-glucose 4,6-dehydratase calS3 Micromonospora echinospora
Micromonospora purpurea		 4.2.1.46
27
 F8K053_STRCT
(F8K053)		 
[query] 3 - 321 (331)
[subject] 5 - 323 (328)
 1e-126 455   72% dTDP-glucose 4,6-dehydratase strE
SCAT_2478		 Streptomyces cattleya 4.2.1.46
28
 Q9F5R6_STRSD
(Q9F5R6)		 
[query] 6 - 324 (331)
[subject] 3 - 325 (332)
 1e-126 454   72% dTDP-glucose 4,6-dehydratase Streptomyces sp. (strain ATCC 17920 / DSM 40477 / NCIB 11028)
Streptomyces tenebrarius		 4.2.1.46
29
 RMLB_STRGR
(P29782)		 
[query] 3 - 325 (331)
[subject] 2 - 323 (328)
 1e-124 451   70% dTDP-glucose 4,6-dehydratase strE Streptomyces griseus 4.2.1.46
30
 Q76KZ7_STRHA
(Q76KZ7)		 Jump to Vicen_00030 
[query] 3 - 321 (331)
[subject] 2 - 315 (323)
 1e-124 449   72% dTDP-glucose 4,6-dehydratase vinB Streptomyces halstedii 4.2.1.46
31
 Q2I756_9ACTO
(Q2I756)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (323)
 1e-123 447   71% dTDP-glucose 4,6-dehydratase plaA3
STTU_1455		 Streptomyces sp. Tu6071 4.2.1.46
32
 Q9RN58_STRNO
(Q9RN58)		 Jump to Nogl_00210 
[query] 2 - 328 (331)
[subject] 9 - 338 (350)
 1e-123 447   69% dTDP-glucose 4,6-dehydratase snogK Streptomyces nogalater 4.2.1.46
33
 F4F6Y4_VERMA
(F4F6Y4)		 
[query] 6 - 325 (331)
[subject] 3 - 330 (333)
 1e-123 446   69% dTDP-glucose 4,6-dehydratase VAB18032_22795 Verrucosispora maris (strain AB-18-032) 4.2.1.46
34
 E4NCQ6_KITSK
(E4NCQ6)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (325)
 1e-123 446   69% dTDP-glucose 4,6-dehydratase rmlB1
KSE_31770		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae		 4.2.1.46
35
 Q9RJE3_STRCO
(Q9RJE3)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (324)
 1e-123 445   72% dTDP-glucose 4,6-dehydratase SCO0749 Streptomyces coelicolor 4.2.1.46
36
 D6EYD0_STRLI
(D6EYD0)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (324)
 1e-123 445   72% dTDP-glucose 4,6-dehydratase SSPG_06849 Streptomyces lividans TK24 4.2.1.46
37
 A0ADF0_STRAM
(A0ADF0)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (348)
 1e-123 444   71% dTDP-glucose 4,6-dehydratase SAMR0797 Streptomyces ambofaciens ATCC 23877 4.2.1.46
38
 Q9RR28_STRAT
(Q9RR28)		 
[query] 5 - 331 (331)
[subject] 2 - 328 (335)
 1e-123 444   68% dTDP-glucose 4,6-dehydratase oleE Streptomyces antibioticus 4.2.1.46
39
 Q9L6C3_STRAT
(Q9L6C3)		 
[query] 5 - 324 (331)
[subject] 2 - 321 (335)
 1e-122 444   69% dTDP-glucose 4,6-dehydratase Streptomyces antibioticus 4.2.1.46
40
 Q3S887_9ACTO
(Q3S887)		 Jump to Conca_00140 
[query] 5 - 324 (331)
[subject] 2 - 322 (326)
 1e-122 443   70% dTDP-glucose 4,6-dehydratase Streptomyces neyagawaensis 4.2.1.46
41
 C6WJ73_ACTMD
(C6WJ73)		 
[query] 6 - 324 (331)
[subject] 3 - 324 (330)
 1e-122 442   69% dTDP-glucose 4,6-dehydratase Amir_6347 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) 4.2.1.46
42
 C9YYJ5_STRSW
(C9YYJ5)		 
[query] 5 - 322 (331)
[subject] 2 - 320 (326)
 1e-122 441   70% dTDP-glucose 4,6-dehydratase SCAB_84041 Streptomyces scabies (strain 87.22)
Streptomyces scabiei		 4.2.1.46
43
 E5F142_9ACTO
(E5F142)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (324)
 1e-122 441   69% dTDP-glucose 4,6-dehydratase rmlB Kitasatospora kifunensis 4.2.1.46
44
 F4CKA6_9PSEU
(F4CKA6)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (324)
 1e-122 441   71% dTDP-glucose 4,6-dehydratase Psed_0177 Pseudonocardia dioxanivorans CB1190 4.2.1.46
45
 Q52V54_9ACTO
(Q52V54)		 
[query] 5 - 319 (331)
[subject] 2 - 318 (328)
 1e-121 440   72% dTDP-glucose 4,6-dehydratase Streptomyces aizunensis 4.2.1.46
46
 C7MUW7_SACVD
(C7MUW7)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (330)
 1e-121 440   68% dTDP-glucose 4,6-dehydratase Svir_06090 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) 4.2.1.46
47
 D8I3S0_AMYMU
(D8I3S0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-121 439   70% dTDP-glucose 4,6-dehydratase rfbB
AMED_1007		 Amycolatopsis mediterranei (strain U-32) 4.2.1.46
48
 D9V6R3_9ACTO
(D9V6R3)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (330)
 1e-119 434   69% dTDP-glucose 4,6-dehydratase SSMG_00677 Streptomyces sp. AA4 4.2.1.46
49
 A4FNM4_SACEN
(A4FNM4)		 
[query] 6 - 325 (331)
[subject] 3 - 324 (329)
 1e-119 432   67% dTDP-glucose 4,6-dehydratase aveBII
SACE_6480		 Saccharopolyspora erythraea (strain NRRL 23338) 4.2.1.46
50
 Q54116_SACER
(Q54116)		 
[query] 6 - 325 (331)
[subject] 3 - 324 (329)
 1e-119 432   67% dTDP-glucose 4,6-dehydratase gdh Saccharopolyspora erythraea
Streptomyces erythraeus		 4.2.1.46
51
 A8KQL1_9ACTO
(A8KQL1)		 Jump to Ello_00270 
[query] 5 - 331 (331)
[subject] 2 - 329 (329)
 1e-119 432   65% dTDP-glucose 4,6-dehydratase rhaB Streptomyces olivaceus 4.2.1.46
52
 D6KEK4_9ACTO
(D6KEK4)		 
[query] 3 - 322 (331)
[subject] 2 - 321 (325)
 1e-119 431   68% dTDP-glucose 4,6-dehydratase SSTG_05379 Streptomyces sp. e14 4.2.1.46
53
 D6AXP0_9ACTO
(D6AXP0)		 
[query] 6 - 324 (331)
[subject] 3 - 321 (331)
 1e-119 431   67% dTDP-glucose 4,6-dehydratase SSHG_05332 Streptomyces albus J1074 4.2.1.46
54
 B0B0U9_STRGA
(B0B0U9)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (325)
 1e-118 429   66% dTDP-glucose 4,6-dehydratase gacB Streptomyces glaucescens 4.2.1.46
55
 Q9KK63_STRRY
(Q9KK63)		 
[query] 7 - 319 (331)
[subject] 4 - 315 (317)
 1e-118 429   68% DTDP-glucose 4,6-dehydratase prmE Streptomyces rimosus subsp. paromomycinus
56
 D7C7L5_STRBB
(D7C7L5)		 
[query] 5 - 313 (331)
[subject] 2 - 312 (315)
 1e-118 428   70% Dehydratase SBI_09445 Streptomyces bingchenggensis (strain BCW-1)
57
 E0L0G4_STRVO
(E0L0G4)		 
[query] 6 - 324 (331)
[subject] 3 - 323 (324)
 1e-118 427   68% dTDP-glucose 4,6-dehydratase StrviDRAFT_8392 Streptomyces violaceusniger Tu 4113 4.2.1.46
58
 D6AT92_STRFL
(D6AT92)		 
[query] 6 - 320 (331)
[subject] 3 - 318 (349)
 1e-117 425   69% dTDP-glucose 4,6-dehydratase SSGG_05536 Streptomyces roseosporus NRRL 15998 4.2.1.46
59
 C7QIW6_CATAD
(C7QIW6)		 
[query] 6 - 322 (331)
[subject] 3 - 318 (338)
 1e-116 424   66% dTDP-glucose 4,6-dehydratase Caci_8193 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) 4.2.1.46
60
 A0ACJ2_STRAM
(A0ACJ2)		 
[query] 6 - 324 (331)
[subject] 3 - 323 (329)
 1e-116 422   67% dTDP-glucose 4,6-dehydratase SAMR0486 Streptomyces ambofaciens ATCC 23877 4.2.1.46
61
 E9L1H3_9ZZZZ
(E9L1H3)		 
[query] 6 - 322 (331)
[subject] 3 - 319 (326)
 1e-116 421   69% Putative uncharacterized protein CA37-29 uncultured organism CA37
62
 RMLB_ACTS5
(Q9ZAE8)		 
[query] 5 - 319 (331)
[subject] 2 - 319 (320)
 1e-115 421   64% dTDP-glucose 4,6-dehydratase acbB Actinoplanes sp. (strain 50/110) 4.2.1.46
63
 Q9S1L0_STRNE
(Q9S1L0)		 
[query] 6 - 324 (331)
[subject] 3 - 323 (328)
 1e-115 420   66% dTDP-glucose 4,6-dehydratase spcJ Streptoverticillium netropsis
Streptoverticillium flavopersicus		 4.2.1.46
64
 B5L6K3_MICCH
(B5L6K3)		 
[query] 1 - 329 (331)
[subject] 1 - 332 (332)
 1e-115 419   65% dTDP-glucose 4,6-dehydratase Micromonospora chalcea 4.2.1.46
65
 Q93EK0_9PSEU
(Q93EK0)		 
[query] 6 - 330 (331)
[subject] 3 - 328 (329)
 1e-115 418   66% dTDP-glucose 4,6-dehydratase gdh Saccharopolyspora spinosa 4.2.1.46
66
 Q9RMG0_STRGL
(Q9RMG0)		 Jump to C1027_00240 
[query] 6 - 331 (331)
[subject] 3 - 330 (332)
 1e-115 418   64% dTDP-glucose 4,6-dehydratase sgcA Streptomyces globisporus 4.2.1.46
67
 A8WEY5_STRST
(A8WEY5)		 
[query] 6 - 324 (331)
[subject] 3 - 322 (330)
 1e-114 417   65% dTDP-glucose 4,6-dehydratase spcE Streptomyces spectabilis 4.2.1.46
68
 A0LRX9_ACIC1
(A0LRX9)		 
[query] 8 - 322 (331)
[subject] 1 - 316 (324)
 1e-114 416   65% dTDP-glucose 4,6-dehydratase Acel_0415 Acidothermus cellulolyticus (strain ATCC 43068 / 11B) 4.2.1.46
69
 B0RDV6_CLAMS
(B0RDV6)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-113 414   65% dTDP-glucose 4,6-dehydratase CMS0629 Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) 4.2.1.46
70
 C4NYL8_9ACTO
(C4NYL8)		 
[query] 6 - 325 (331)
[subject] 3 - 322 (326)
 1e-113 414   66% dTDP-glucose 4,6-dehydratase saqH Micromonospora sp. Tu 6368 4.2.1.46
71
 A4AI60_9ACTN
(A4AI60)		 
[query] 5 - 322 (331)
[subject] 2 - 321 (327)
 1e-113 413   65% dTDP-glucose 4,6-dehydratase A20C1_06126 marine actinobacterium PHSC20C1 4.2.1.46
72
 C8XIN5_NAKMY
(C8XIN5)		 
[query] 6 - 322 (331)
[subject] 3 - 323 (331)
 1e-113 412   65% dTDP-glucose 4,6-dehydratase Namu_4211 Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104)
Microsphaera multipartita		 4.2.1.46
73
 Q9S0P5_STRAW
(Q9S0P5)		 Jump to Aver_00120 
[query] 8 - 323 (331)
[subject] 1 - 318 (355)
 1e-113 411   66% dTDP-glucose 4,6-dehydratase aveBII
SAV946
SAV_946		 Streptomyces avermitilis 4.2.1.46
74
 Q83WD7_MICGR
(Q83WD7)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (342)
 1e-113 411   66% dTDP-glucose 4,6-dehydratase mydB Micromonospora griseorubida 4.2.1.46
75
 Q9ZGH3_9ACTO
(Q9ZGH3)		 Jump to Pikro_00130 
[query] 6 - 322 (331)
[subject] 3 - 321 (337)
 1e-112 411   65% dTDP-glucose 4,6-dehydratase desIV Streptomyces venezuelae 4.2.1.46
76
 Q8KRX3_9ACTO
(Q8KRX3)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (344)
 1e-112 409   66% dTDP-glucose 4,6-dehydratase nbmH Streptomyces narbonensis 4.2.1.46
77
 A5CPQ0_CLAM3
(A5CPQ0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-112 409   65% dTDP-glucose 4,6-dehydratase rmlB
CMM_1010		 Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) 4.2.1.46
78
 D9WEH5_9ACTO
(D9WEH5)		 
[query] 6 - 328 (331)
[subject] 3 - 325 (327)
 1e-112 408   65% dTDP-glucose 4,6-dehydratase SSOG_02928 Streptomyces himastatinicus ATCC 53653 4.2.1.46
79
 Q6AGM1_LEIXX
(Q6AGM1)		 
[query] 5 - 322 (331)
[subject] 2 - 321 (329)
 1e-111 407   63% dTDP-glucose 4,6-dehydratase Lxx04910 Leifsonia xyli subsp. xyli 4.2.1.46
80
 Q9F8T0_9ACTO
(Q9F8T0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (336)
 1e-111 406   66% dTDP-glucose 4,6-dehydratase couT Streptomyces rishiriensis 4.2.1.46
81
 E4N8V2_KITSK
(E4N8V2)		 
[query] 6 - 330 (331)
[subject] 3 - 327 (330)
 1e-111 404   65% dTDP-glucose 4,6-dehydratase rmlB2
KSE_18080		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae		 4.2.1.46
82
 Q9L9E8_STRSH
(Q9L9E8)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (336)
 1e-110 404   66% dTDP-glucose 4,6-dehydratase novT Streptomyces spheroides
Streptomyces caeruleus		 4.2.1.46
83
 D2B1Y0_STRRD
(D2B1Y0)		 
[query] 6 - 322 (331)
[subject] 3 - 320 (325)
 1e-110 402   65% dTDP-glucose 4,6-dehydratase Sros_6490 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) 4.2.1.46
84
 D2SG25_GEOOG
(D2SG25)		 
[query] 6 - 325 (331)
[subject] 3 - 325 (331)
 1e-110 401   64% dTDP-glucose 4,6-dehydratase Gobs_4331 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) 4.2.1.46
85
 B3TMR2_9ACTO
(B3TMR2)		 
[query] 3 - 322 (331)
[subject] 4 - 325 (342)
 1e-110 401   62% dTDP-glucose 4,6-dehydratase KijD4 Actinomadura kijaniata 4.2.1.46
86
 C4RP68_9ACTO
(C4RP68)		 
[query] 6 - 324 (331)
[subject] 5 - 322 (330)
 1e-109 400   64% dTDP-glucose 4,6-dehydratase MCAG_03631 Micromonospora sp. ATCC 39149 4.2.1.46
87
 B8Y4F0_STRAU
(B8Y4F0)		 
[query] 6 - 320 (331)
[subject] 3 - 317 (337)
 1e-109 399   65% dTDP-glucose 4,6-dehydratase aur1T Streptomyces aureofaciens 4.2.1.46
88
 D7BZT0_STRBB
(D7BZT0)		 
[query] 6 - 324 (331)
[subject] 3 - 321 (322)
 1e-108 397   64% dTDP-glucose 4,6-dehydratase SBI_06865 Streptomyces bingchenggensis (strain BCW-1) 4.2.1.46
89
 Q2PZR3_9ACTO
(Q2PZR3)		 Jump to Cosmo_00130 
[query] 5 - 320 (331)
[subject] 2 - 317 (327)
 1e-108 397   64% dTDP-glucose 4,6-dehydratase cosH Streptomyces olindensis 4.2.1.46
90
 D1A6U0_THECD
(D1A6U0)		 
[query] 6 - 329 (331)
[subject] 3 - 326 (336)
 1e-108 397   60% dTDP-glucose 4,6-dehydratase Tcur_2799 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081) 4.2.1.46
91
 A8Y8J5_STRAM
(A8Y8J5)		 
[query] 6 - 324 (331)
[subject] 23 - 343 (345)
 1e-108 397   66% dTDP-glucose 4,6-dehydratase srm5 Streptomyces ambofaciens 4.2.1.46
92
 E3T495_9ACTO
(E3T495)		 
[query] 6 - 319 (331)
[subject] 3 - 316 (321)
 1e-108 395   63% dTDP-glucose 4,6-dehydratase gra-orf17 Streptomyces vietnamensis 4.2.1.46
93
 A8M278_SALAI
(A8M278)		 
[query] 6 - 320 (331)
[subject] 3 - 322 (357)
 1e-108 395   62% dTDP-glucose 4,6-dehydratase Sare_2336 Salinispora arenicola (strain CNS-205) 4.2.1.46
94
 Q7WT24_9ACTO
(Q7WT24)		 Jump to Medem_00180 
[query] 6 - 322 (331)
[subject] 3 - 319 (333)
 1e-108 395   61% dTDP-glucose 4,6-dehydratase med-ORF17 Streptomyces sp. AM-7161 4.2.1.46
95
 Q9ZGC7_STRCY
(Q9ZGC7)		 Jump to Lando_00130 
[query] 5 - 320 (331)
[subject] 3 - 318 (326)
 1e-108 395   63% dTDP-glucose 4,6-dehydratase lanH14 Streptomyces cyanogenus 4.2.1.46
96
 Q8RS23_STRVL
(Q8RS23)		 
[query] 5 - 320 (331)
[subject] 2 - 317 (327)
 1e-108 395   64% dTDP-glucose 4,6-dehydratase rhoH Streptomyces violaceus
Streptomyces venezuelae		 4.2.1.46
97
 Q54144_STRFR
(Q54144)		 
[query] 6 - 328 (331)
[subject] 3 - 327 (333)
 1e-108 395   63% dTDP-glucose 4,6-dehydratase Streptomyces fradiae
Streptomyces roseoflavus		 4.2.1.46
98
 Q2HR54_9ACTO
(Q2HR54)		 Jump to Sch475_00260 
[query] 6 - 320 (331)
[subject] 3 - 317 (328)
 1e-107 393   62% dTDP-glucose 4,6-dehydratase schS5 Streptomyces sp. SCC 2136 4.2.1.46
99
 Q0R4N2_STRAT
(Q0R4N2)		 Jump to Chth_00220 
[query] 7 - 322 (331)
[subject] 4 - 319 (327)
 1e-107 393   64% dTDP-glucose 4,6-dehydratase Streptomyces antibioticus 4.2.1.46
100
 Q83NY1_TROW8
(Q83NY1)		 
[query] 4 - 322 (331)
[subject] 2 - 321 (327)
 1e-107 393   59% dTDP-glucose 4,6-dehydratase TW033 Tropheryma whipplei (strain TW08/27)
Whipple's bacillus		 4.2.1.46
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q194R3_STRAA
(Q194R3)		 
[query] 1 - 331 (331)
[subject] 1 - 331 (331)
 0.0 671   100%
Product
dTDP-glucose 4,6-dehydratase
Gene
mtmE
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
2
 D9UBQ9_STRPR
(D9UBQ9)		 
[query] 3 - 322 (331)
[subject] 2 - 321 (335)
 1e-145 519   80%
Product
dTDP-glucose 4,6-dehydratase
Gene
cpp25
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
10
 D6MSX9_9ACTO
(D6MSX9)		 
[query] 3 - 324 (331)
[subject] 2 - 323 (327)
 1e-139 499   76%
Product
dTDP-glucose 4,6-dehydratase
Gene
ssfS2
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
11
 Q7X2H7_9ACTO
(Q7X2H7)		 Jump to Gilvo_00130 
[query] 1 - 322 (331)
[subject] 1 - 325 (336)
 1e-136 488   73%
Product
dTDP-glucose 4,6-dehydratase
Gene
gilE
Organism
Streptomyces griseoflavus
1uniprot[Pubmed] 12822997 [Medline] 22708304
The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003]
12
 D9I0H4_9ACTO
(D9I0H4)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (326)
 1e-134 483   75%
Product
dTDP-glucose 4,6-dehydratase
Gene
cpzDIII
Organism
Streptomyces sp. MK730-62F2
1uniprot[Pubmed] 20418426
Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.(Appl. Environ. Microbiol.) [2010]
14
 D1GLU6_9ACTO
(D1GLU6)		 Jump to Strply_00180 
[query] 5 - 327 (331)
[subject] 2 - 327 (328)
 1e-133 479   74%
Product
dTDP-glucose 4,6-dehydratase
Gene
slgS2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
18
 D3Y166_STRPT
(D3Y166)		 
[query] 3 - 325 (331)
[subject] 41 - 363 (368)
 1e-127 459   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
strE
Organism
Streptomyces platensis
1uniprot[Pubmed] 20067498
Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010]
19
 B1W376_STRGG
(B1W376)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (329)
 1e-127 459   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
strE
SGR_5929
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
21
 Q7WTE5_9ACTO
(Q7WTE5)		 Jump to Nanch_00180 
[query] 5 - 325 (331)
[subject] 2 - 324 (331)
 1e-127 457   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
nanG2
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
24
 D7BSN0_STRBB
(D7BSN0)		 
[query] 5 - 325 (331)
[subject] 2 - 324 (331)
 1e-126 456   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
nanG2
SBI_08409
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
25
 O86866_STRGA
(O86866)		 
[query] 4 - 322 (331)
[subject] 3 - 320 (329)
 1e-126 456   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
strE
Organism
Streptomyces glaucescens
1uniprot[Pubmed] 8628239 [Medline] 96204519
The str gene cluster for the biosynthesis of 5'-hydroxystreptomycin in Streptomyces glaucescens GLA.0 (ETH 22794): new operons and evidence for pathway-specific regulation by StrR.(Mol. Gen. Genet.) [1996]
2uniprot
Streptomycin Production in Streptomycetes: a Progress Report.(INDUSTRIAL MICROORGANISMS. BASIC AND APPLIED MOLECULAR GENETICS) [1993]
26
 Q8KNI5_MICEC
(Q8KNI5)		 Jump to Calm_00120 
[query] 1 - 324 (331)
[subject] 1 - 326 (343)
 1e-126 455   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
calS3
Organism
Micromonospora echinospora
Micromonospora purpurea
1uniprot[Pubmed] 12183629 [Medline] 22171414
The calicheamicin gene cluster and its iterative type I enediyne PKS.(Science) [2002]
28
 Q9F5R6_STRSD
(Q9F5R6)		 
[query] 6 - 324 (331)
[subject] 3 - 325 (332)
 1e-126 454   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces sp. (strain ATCC 17920 / DSM 40477 / NCIB 11028)
Streptomyces tenebrarius
1uniprot[Pubmed] 11517612 [Medline] 21409420
Cloning of the sugar related biosynthesis gene cluster from Streptomyces tenebrarius H6(Sheng Wu Gong Cheng Xue Bao) [2001]
29
 RMLB_STRGR
(P29782)		 
[query] 3 - 325 (331)
[subject] 2 - 323 (328)
 1e-124 451   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
strE
Organism
Streptomyces griseus
1uniprot[Pubmed] 1661369 [Medline] 92092953
Genetics of streptomycin production in Streptomyces griseus: molecular structure and putative function of genes strELMB2N.(Mol. Gen. Genet.) [1991]
30
 Q76KZ7_STRHA
(Q76KZ7)		 Jump to Vicen_00030 
[query] 3 - 321 (331)
[subject] 2 - 315 (323)
 1e-124 449   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
vinB
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
31
 Q2I756_9ACTO
(Q2I756)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (323)
 1e-123 447   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
plaA3
STTU_1455
Organism
Streptomyces sp. Tu6071
1uniprot[Pubmed] 16632249
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives.(Chem. Biol.) [2006]
32
 Q9RN58_STRNO
(Q9RN58)		 Jump to Nogl_00210 
[query] 2 - 328 (331)
[subject] 9 - 338 (350)
 1e-123 447   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
snogK
Organism
Streptomyces nogalater
1uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
2uniprot[Pubmed] 10639368 [Medline] 20106987
Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000]
[pubmed all]
33
 F4F6Y4_VERMA
(F4F6Y4)		 
[query] 6 - 325 (331)
[subject] 3 - 330 (333)
 1e-123 446   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
VAB18032_22795
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
34
 E4NCQ6_KITSK
(E4NCQ6)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (325)
 1e-123 446   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB1
KSE_31770
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
35
 Q9RJE3_STRCO
(Q9RJE3)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (324)
 1e-123 445   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
SCO0749
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
37
 A0ADF0_STRAM
(A0ADF0)		 
[query] 5 - 324 (331)
[subject] 2 - 319 (348)
 1e-123 444   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
SAMR0797
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
38
 Q9RR28_STRAT
(Q9RR28)		 
[query] 5 - 331 (331)
[subject] 2 - 328 (335)
 1e-123 444   68%
Product
dTDP-glucose 4,6-dehydratase
Gene
oleE
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10770761 [Medline] 20233594
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.(Antimicrob. Agents Chemother.) [2000]
39
 Q9L6C3_STRAT
(Q9L6C3)		 
[query] 5 - 324 (331)
[subject] 2 - 321 (335)
 1e-122 444   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces antibioticus
1uniprot
Mechanism of the 2-deoxygenation step in the biosynthesis of the deoxyhexose moieties of the antibiotics granaticin and oleandomycin.(J. Am. Chem. Soc.) [1999]
40
 Q3S887_9ACTO
(Q3S887)		 Jump to Conca_00140 
[query] 5 - 324 (331)
[subject] 2 - 322 (326)
 1e-122 443   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
41
 C6WJ73_ACTMD
(C6WJ73)		 
[query] 6 - 324 (331)
[subject] 3 - 324 (330)
 1e-122 442   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
Amir_6347
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
42
 C9YYJ5_STRSW
(C9YYJ5)		 
[query] 5 - 322 (331)
[subject] 2 - 320 (326)
 1e-122 441   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
SCAB_84041
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
43
 E5F142_9ACTO
(E5F142)		 
[query] 6 - 322 (331)
[subject] 3 - 317 (324)
 1e-122 441   69%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB
Organism
Kitasatospora kifunensis
1uniprot[Pubmed] 20667525
Cloning and in vitro characterization of dTDP-6-deoxy-L-talose biosynthetic genes from Kitasatospora kifunensis featuring the dTDP-6-deoxy-L-lyxo-4-hexulose reductase that synthesizes dTDP-6-deoxy-L-talose.(Carbohydr. Res.) [2010]
45
 Q52V54_9ACTO
(Q52V54)		 
[query] 5 - 319 (331)
[subject] 2 - 318 (328)
 1e-121 440   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
46
 C7MUW7_SACVD
(C7MUW7)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (330)
 1e-121 440   68%
Product
dTDP-glucose 4,6-dehydratase
Gene
Svir_06090
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
47
 D8I3S0_AMYMU
(D8I3S0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-121 439   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
rfbB
AMED_1007
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
49
 A4FNM4_SACEN
(A4FNM4)		 
[query] 6 - 325 (331)
[subject] 3 - 324 (329)
 1e-119 432   67%
Product
dTDP-glucose 4,6-dehydratase
Gene
aveBII
SACE_6480
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
50
 Q54116_SACER
(Q54116)		 
[query] 6 - 325 (331)
[subject] 3 - 324 (329)
 1e-119 432   67%
Product
dTDP-glucose 4,6-dehydratase
Gene
gdh
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 7883182 [Medline] 95189100
Cloning of the genes encoding thymidine diphosphoglucose 4,6-dehydratase and thymidine diphospho-4-keto-6-deoxyglucose 3,5-epimerase from the erythromycin-producing Saccharopolyspora erythraea.(Gene) [1995]
51
 A8KQL1_9ACTO
(A8KQL1)		 Jump to Ello_00270 
[query] 5 - 331 (331)
[subject] 2 - 329 (329)
 1e-119 432   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
rhaB
Organism
Streptomyces olivaceus
1uniprot[Pubmed] 18310024
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008]
54
 B0B0U9_STRGA
(B0B0U9)		 
[query] 3 - 325 (331)
[subject] 2 - 324 (325)
 1e-118 429   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
gacB
Organism
Streptomyces glaucescens
1uniprot[Pubmed] 19059289
The gac-gene cluster for the production of acarbose from Streptomyces glaucescens GLA.O: identification, isolation and characterization.(J. Biotechnol.) [2009]
56
 D7C7L5_STRBB
(D7C7L5)		 
[query] 5 - 313 (331)
[subject] 2 - 312 (315)
 1e-118 428   70%
Product
Dehydratase
Gene
SBI_09445
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
59
 C7QIW6_CATAD
(C7QIW6)		 
[query] 6 - 322 (331)
[subject] 3 - 318 (338)
 1e-116 424   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
Caci_8193
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
60
 A0ACJ2_STRAM
(A0ACJ2)		 
[query] 6 - 324 (331)
[subject] 3 - 323 (329)
 1e-116 422   67%
Product
dTDP-glucose 4,6-dehydratase
Gene
SAMR0486
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
61
 E9L1H3_9ZZZZ
(E9L1H3)		 
[query] 6 - 322 (331)
[subject] 3 - 319 (326)
 1e-116 421   69%
Product
Putative uncharacterized protein
Gene
CA37-29
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
62
 RMLB_ACTS5
(Q9ZAE8)		 
[query] 5 - 319 (331)
[subject] 2 - 319 (320)
 1e-115 421   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
acbB
Organism
Actinoplanes sp. (strain 50/110)
1uniprot[Pubmed] 10196166 [Medline] 99214159
The AcbC protein from Actinoplanes species is a C7-cyclitol synthase related to 3-dehydroquinate synthases and is involved in the biosynthesis of the alpha-glucosidase inhibitor acarbose.(J. Biol. Chem.) [1999]
64
 B5L6K3_MICCH
(B5L6K3)		 
[query] 1 - 329 (331)
[subject] 1 - 332 (332)
 1e-115 419   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
65
 Q93EK0_9PSEU
(Q93EK0)		 
[query] 6 - 330 (331)
[subject] 3 - 328 (329)
 1e-115 418   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
gdh
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11544225 [Medline] 21429236
Rhamnose biosynthesis pathway supplies precursors for primary and secondary metabolism in Saccharopolyspora spinosa.(J. Bacteriol.) [2001]
66
 Q9RMG0_STRGL
(Q9RMG0)		 Jump to C1027_00240 
[query] 6 - 331 (331)
[subject] 3 - 330 (332)
 1e-115 418   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
sgcA
Organism
Streptomyces globisporus
1uniprot[Pubmed] 10639366 [Medline] 20106985
Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.(Antimicrob. Agents Chemother.) [2000]
2uniprot[Pubmed] 12183628 [Medline] 22171413
Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002]
[pubmed all]
67
 A8WEY5_STRST
(A8WEY5)		 
[query] 6 - 324 (331)
[subject] 3 - 322 (330)
 1e-114 417   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
spcE
Organism
Streptomyces spectabilis
1uniprot[Pubmed] 10650224 [Medline] 20117819
An efficient approach for cloning the dNDP-glucose synthase gene from actinomycetes and its application in Streptomyces spectabilis, a spectinomycin producer.(FEMS Microbiol. Lett.) [2000]
2uniprot[Pubmed] 18663525
The Gene Cluster for Spectinomycin Biosynthesis and the Aminoglycoside-Resistance Function of spcM in Streptomyces spectabilis.(Curr. Microbiol.) [2008]
[pubmed all]
69
 B0RDV6_CLAMS
(B0RDV6)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-113 414   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
CMS0629
Organism
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667)
1uniprot[Pubmed] 18192393
Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation.(J. Bacteriol.) [2008]
70
 C4NYL8_9ACTO
(C4NYL8)		 
[query] 6 - 325 (331)
[subject] 3 - 322 (326)
 1e-113 414   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
saqH
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
73
 Q9S0P5_STRAW
(Q9S0P5)		 Jump to Aver_00120 
[query] 8 - 323 (331)
[subject] 1 - 318 (355)
 1e-113 411   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
aveBII
SAV946
SAV_946
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
74
 Q83WD7_MICGR
(Q83WD7)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (342)
 1e-113 411   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
mydB
Organism
Micromonospora griseorubida
1uniprot[Pubmed] 12583909 [Medline] 22472038
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
75
 Q9ZGH3_9ACTO
(Q9ZGH3)		 Jump to Pikro_00130 
[query] 6 - 322 (331)
[subject] 3 - 321 (337)
 1e-112 411   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
desIV
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
2uniprot[Pubmed] 14570895
High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae.(J. Biol. Chem.) [2004]
[pubmed all]
77
 A5CPQ0_CLAM3
(A5CPQ0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (329)
 1e-112 409   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB
CMM_1010
Organism
Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
1uniprot[Pubmed] 18192381
The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity.(J. Bacteriol.) [2008]
79
 Q6AGM1_LEIXX
(Q6AGM1)		 
[query] 5 - 322 (331)
[subject] 2 - 321 (329)
 1e-111 407   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
Lxx04910
Organism
Leifsonia xyli subsp. xyli
1uniprot[Pubmed] 15305603
The genome sequence of the Gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli.(Mol. Plant Microbe Interact.) [2004]
80
 Q9F8T0_9ACTO
(Q9F8T0)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (336)
 1e-111 406   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
couT
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 11036020 [Medline] 20493109
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000]
81
 E4N8V2_KITSK
(E4N8V2)		 
[query] 6 - 330 (331)
[subject] 3 - 327 (330)
 1e-111 404   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB2
KSE_18080
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
82
 Q9L9E8_STRSH
(Q9L9E8)		 
[query] 6 - 322 (331)
[subject] 3 - 321 (336)
 1e-110 404   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
novT
Organism
Streptomyces spheroides
Streptomyces caeruleus
1uniprot[Pubmed] 10770754 [Medline] 20233587
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000]
83
 D2B1Y0_STRRD
(D2B1Y0)		 
[query] 6 - 322 (331)
[subject] 3 - 320 (325)
 1e-110 402   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
Sros_6490
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
85
 B3TMR2_9ACTO
(B3TMR2)		 
[query] 3 - 322 (331)
[subject] 4 - 325 (342)
 1e-110 401   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
KijD4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
87
 B8Y4F0_STRAU
(B8Y4F0)		 
[query] 6 - 320 (331)
[subject] 3 - 317 (337)
 1e-109 399   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
aur1T
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 20490753
Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.(Folia Microbiol. (Praha)) [2010]
88
 D7BZT0_STRBB
(D7BZT0)		 
[query] 6 - 324 (331)
[subject] 3 - 321 (322)
 1e-108 397   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
SBI_06865
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
89
 Q2PZR3_9ACTO
(Q2PZR3)		 Jump to Cosmo_00130 
[query] 5 - 320 (331)
[subject] 2 - 317 (327)
 1e-108 397   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
cosH
Organism
Streptomyces olindensis
1uniprot[Pubmed] 16810496
Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.(Appl. Microbiol. Biotechnol.) [2006]
90
 D1A6U0_THECD
(D1A6U0)		 
[query] 6 - 329 (331)
[subject] 3 - 326 (336)
 1e-108 397   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
Tcur_2799
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
91
 A8Y8J5_STRAM
(A8Y8J5)		 
[query] 6 - 324 (331)
[subject] 23 - 343 (345)
 1e-108 397   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
srm5
Organism
Streptomyces ambofaciens
1uniprot
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
94
 Q7WT24_9ACTO
(Q7WT24)		 Jump to Medem_00180 
[query] 6 - 322 (331)
[subject] 3 - 319 (333)
 1e-108 395   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
med-ORF17
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
95
 Q9ZGC7_STRCY
(Q9ZGC7)		 Jump to Lando_00130 
[query] 5 - 320 (331)
[subject] 3 - 318 (326)
 1e-108 395   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
lanH14
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
97
 Q54144_STRFR
(Q54144)		 
[query] 6 - 328 (331)
[subject] 3 - 327 (333)
 1e-108 395   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7984112 [Medline] 95075319
Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome.(Mol. Microbiol.) [1994]
98
 Q2HR54_9ACTO
(Q2HR54)		 Jump to Sch475_00260 
[query] 6 - 320 (331)
[subject] 3 - 317 (328)
 1e-107 393   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
schS5
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
99
 Q0R4N2_STRAT
(Q0R4N2)		 Jump to Chth_00220 
[query] 7 - 322 (331)
[subject] 4 - 319 (327)
 1e-107 393   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
100
 Q83NY1_TROW8
(Q83NY1)		 
[query] 4 - 322 (331)
[subject] 2 - 321 (327)
 1e-107 393   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
TW033
Organism
Tropheryma whipplei (strain TW08/27)
Whipple's bacillus
1uniprot[Pubmed] 12606174 [Medline] 22495039
Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei.(Lancet) [2003]