BLAST table : Adria_00080

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q54819_STRPE (Q54819)	0.0	702	100%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	dnrL	Streptomyces peucetius
2	C6K8M0_STRPE (C6K8M0)	1e-168	594	88%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	dnmL	Streptomyces peucetius ATCC 27952
3	D9UBR0_STRPR (D9UBR0)	1e-129	467	69%	UniProt GenBank	Putative dTDP-glucose synthase	cpp24	Streptomyces pristinaespiralis	2.7.7.24 niceE keggE
4	B5HIU2_STRPR (B5HIU2)	1e-129	467	69%	UniProt GenBank	dTDP-glucose synthase	SSDG_05079	Streptomyces pristinaespiralis ATCC 25486
5	Q194R4_STRAA (Q194R4)	1e-126	457	67%	UniProt GenBank	DTDP-glucose synthase	mtmD	Streptomyces argillaceus
6	D9Y1L7_9ACTO (D9Y1L7)	1e-126	457	67%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSRG_04186	Streptomyces griseoflavus Tu4000
7	B5HXA6_9ACTO (B5HXA6)	1e-123	447	65%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSEG_09374	Streptomyces sviceus ATCC 29083
8	D6A3M0_9ACTO (D6A3M0)	1e-123	445	65%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSFG_04775	Streptomyces ghanaensis ATCC 14672
9	C5J045_STRPE (C5J045)	1e-122	443	63%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rmbA	Streptomyces peucetius ATCC 27952
10	B5H783_STRPR (B5H783)	1e-122	443	63%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSDG_01264	Streptomyces pristinaespiralis ATCC 25486
11	D1H0J0_9ACTO (D1H0J0)	1e-122	443	65%	UniProt GenBank	Putative NDP-glucose synthase	ravD	Streptomyces sp. C23201NS3
12	D1XFK6_9ACTO (D1XFK6)	1e-120	434	63%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	SACTEDRAFT_1466	Streptomyces sp. SA3_actE
13	Q7X2H1_9ACTO (Q7X2H1)	1e-119	432	64%	UniProt GenBank	Putative NDP-glucose synthase	gilD	Streptomyces griseoflavus
14	D1H0B1_9ACTO (D1H0B1)	1e-117	426	62%	UniProt GenBank	Putative glucose-1-phosphate thymidylyltransferase	chryD	Streptomyces albaduncus
15	D6MSX8_9ACTO (D6MSX8)	1e-115	420	61%	UniProt GenBank	SsfS1	ssfS1	Streptomyces sp. SF2575
16	D1GLU7_9ACTO (D1GLU7)	1e-114	417	62%	UniProt GenBank	NDP-glucose synthase	slgS1	Streptomyces lydicus
17	D3Y167_STRPT (D3Y167)	1e-114	416	62%	UniProt GenBank	Putative glucose-1-phosphate thymidylyltransferase	strD	Streptomyces platensis
18	B1W377_STRGG (B1W377)	1e-113	414	60%	UniProt GenBank	Putative glucose-1-phosphate thymidylyltransferase	strD SGR_5930	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
19	Q53ID2_STRGR (Q53ID2)	1e-113	414	60%	UniProt GenBank	DTTP:alpha-D-glucose-1-phosphate thymidylyltransferase StrD	strD SG7F10.20c	Streptomyces griseus subsp. griseus	2.7.7.24 niceE keggE
20	D9I0H3_9ACTO (D9I0H3)	1e-113	412	58%	UniProt GenBank	dTDP-glucose synthase	cpzDII	Streptomyces sp. MK730-62F2
21	D9XDA7_STRVR (D9XDA7)	1e-112	410	60%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSQG_07272	Streptomyces viridochromogenes DSM 40736
22	RMLA_STRGR (P08075)	1e-112	409	59%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase Sugar-nucleotidylation enzyme dTDP-glucose pyrophosphorylase dTDP-glucose synthase	strD	Streptomyces griseus	2.7.7.24 niceE keggE
23	D9W4I3_9ACTO (D9W4I3)	1e-112	409	62%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSNG_07063	Streptomyces sp. C
24	D9Y261_9ACTO (D9Y261)	1e-111	405	59%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSRG_05858	Streptomyces griseoflavus Tu4000
25	Q9X5K7_9ACTO (Q9X5K7)	1e-110	404	60%	UniProt GenBank	BlmD	blmD	Streptomyces bluensis
26	Q400H3_THECA (Q400H3)	1e-109	400	58%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rmlA	Thermus caldophilus	2.7.7.24 niceE keggE
27	Q83WG7_9ACTO (Q83WG7)	1e-109	399	62%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	staA	Streptomyces sp. TP-A0274
28	C4RP67_9ACTO (C4RP67)	1e-109	398	58%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	MCAG_03630	Micromonospora sp. ATCC 39149
29	C9W344_9ACTO (C9W344)	1e-108	396	60%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	nokF	Nonomuraea longicatena
30	Q76KZ8_STRHA (Q76KZ8)	1e-108	396	57%	UniProt GenBank	DTDP-glucose synthase	vinA	Streptomyces halstedii
31	O86865_STRGA (O86865)	1e-107	394	60%	UniProt GenBank	StrD	strD	Streptomyces glaucescens
32	D2B4G8_STRRD (D2B4G8)	1e-107	393	59%	UniProt GenBank	dTDP-glucose pyrophosphorylase-like protein	Sros_0631	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
33	C7G1T7_STRGR (C7G1T7)	1e-106	389	58%	UniProt GenBank	Putative thymidylyltransferase		Streptomyces griseus
34	Q9L6C4_STRAT (Q9L6C4)	1e-105	385	58%	UniProt GenBank	DTDP-D-glucose synthase		Streptomyces antibioticus
35	Q9RR29_STRAT (Q9RR29)	1e-104	382	57%	UniProt GenBank	DTDP-D-glucose synthase	oleS	Streptomyces antibioticus
36	E1CG48_9ACTO (E1CG48)	1e-104	381	58%	UniProt GenBank	Putative glucose-1-phosphate thymidylyltransferase	capR	Streptomyces sp. SANK 62799
37	Q0RRD1_FRAAA (Q0RRD1)	1e-103	381	57%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)	FRAAL1228	Frankia alni (strain ACN14a)	2.7.7.24 niceE keggE
38	E9L1G5_9ZZZZ (E9L1G5)	1e-103	379	55%	UniProt GenBank	Putative uncharacterized protein	CA37-21	uncultured organism CA37
39	A0LRX7_ACIC1 (A0LRX7)	1e-103	378	56%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Acel_0413	Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
40	F8AY39_9ACTO (F8AY39)	1e-102	376	57%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	FsymDg_1038	Frankia symbiont of Datisca glomerata	2.7.7.24 niceE keggE
41	E9L1R0_9ZZZZ (E9L1R0)	1e-102	375	55%	UniProt GenBank	Putative uncharacterized protein	CA915-18	uncultured organism CA915
42	A8L9V7_FRASN (A8L9V7)	1e-101	373	55%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Franean1_5901	Frankia sp. (strain EAN1pec)
43	D2B1Y1_STRRD (D2B1Y1)	1e-101	372	55%	UniProt GenBank	dTDP-glucose pyrophosphorylase-like protein	Sros_6491	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
44	D5SL13_STRCL (D5SL13)	1e-100	371	57%	UniProt GenBank	Staurosporine biosynthesis glucose-1-phosphate thymidyltransferase StaA	staA SCLAV_p1120	Streptomyces clavuligerus ATCC 27064	2.7.7.24 niceE keggE
45	B5H2M6_STRCL (B5H2M6)	1e-98	364	57%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	SSCG_05849	Streptomyces clavuligerus ATCC 27064
46	Q2JF45_FRASC (Q2JF45)	2e-98	363	54%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Francci3_0713	Frankia sp. (strain CcI3)
47	D6AT91_STRFL (D6AT91)	3e-98	363	53%	UniProt GenBank	dTDP-glucose synthase	SSGG_05535	Streptomyces roseosporus NRRL 15998
48	E5RLM7_9ACTO (E5RLM7)	9e-98	361	53%	UniProt GenBank	Putative glucose-1-phosphate thymidylyltransferase	pnxS1	Streptomyces sp. TA-0256
49	O05171_STRVR (O05171)	2e-94	350	53%	UniProt GenBank	Putative dTDP glucose synthetase	aviD	Streptomyces viridochromogenes
50	Q52V55_9ACTO (Q52V55)	4e-94	349	56%	UniProt GenBank	Sugar nucleotidyltransferase		Streptomyces aizunensis
51	D7C7L4_STRBB (D7C7L4)	6e-94	348	56%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	SBI_09444	Streptomyces bingchenggensis (strain BCW-1)
52	B0B0U8_STRGA (B0B0U8)	3e-93	346	52%	UniProt GenBank	dTDP-glucose synthase GacA	gacA	Streptomyces glaucescens
53	C0JWC0_9ACTO (C0JWC0)	3e-92	343	54%	UniProt GenBank	PokS1	pokS1	Streptomyces diastatochromogenes
54	B9LGS0_CHLSY (B9LGS0)	2e-90	337	51%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Chy400_2122	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)
55	A9WE24_CHLAA (A9WE24)	2e-90	337	51%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Caur_1968	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
56	B8GB86_CHLAD (B8GB86)	4e-90	336	51%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Cagg_1817	Chloroflexus aggregans (strain MD-66 / DSM 9485)
57	Q0R4N1_STRAT (Q0R4N1)	1e-89	334	50%	UniProt GenBank	ChlC1		Streptomyces antibioticus
58	Q2HR55_9ACTO (Q2HR55)	2e-89	334	49%	UniProt GenBank	Putative dNDP-glucose synthetase	schS6	Streptomyces sp. SCC 2136
59	E3T494_9ACTO (E3T494)	2e-89	333	52%	UniProt GenBank	Putative dTDP-1-glucose synthase	gra-orf16	Streptomyces vietnamensis
60	B0LJ32_9ACTO (B0LJ32)	3e-89	333	50%	UniProt GenBank	Lct49	lct49	Streptomyces rishiriensis
61	D5ML11_9BACT (D5ML11)	3e-88	330	51%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)	strD DAMO_2778	NC10 bacterium 'Dutch sediment'	2.7.7.24 niceE keggE
62	Q0H2X0_9ACTO (Q0H2X0)	1e-87	328	54%	UniProt GenBank	Putative sugar activating enzyme	atS7	Actinomadura melliaura
63	E1IIP0_9CHLR (E1IIP0)	1e-87	328	51%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	OSCT_3191	Oscillochloris trichoides DG-6
64	Q9ZGC8_STRCY (Q9ZGC8)	1e-87	327	46%	UniProt GenBank	NDP-hexose synthetase homolog	lanG	Streptomyces cyanogenus
65	D9WEH6_9ACTO (D9WEH6)	2e-87	327	49%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	SSOG_02929	Streptomyces himastatinicus ATCC 53653
66	A9AWN8_HERA2 (A9AWN8)	3e-87	326	49%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Haur_4165	Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
67	A1YZ54_9ACTO (A1YZ54)	9e-86	322	52%	UniProt GenBank	PdmX	pdmX	Actinomadura hibisca
68	Q9RPA6_STRFR (Q9RPA6)	7e-85	318	48%	UniProt GenBank	DNDP-glucose synthetase	urdG	Streptomyces fradiae Streptomyces roseoflavus
69	D7BZS9_STRBB (D7BZS9)	8e-84	315	48%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	SBI_06864	Streptomyces bingchenggensis (strain BCW-1)
70	Q70J86_STRGR (Q70J86)	9e-83	311	48%	UniProt GenBank	NDP-glucose synthase	cmmD	Streptomyces griseus subsp. griseus
71	Q7WT25_9ACTO (Q7WT25)	1e-82	311	47%	UniProt GenBank	NDP-1-glucose synthase	med-ORF18	Streptomyces sp. AM-7161
72	Q8GMI0_STRGL (Q8GMI0)	3e-82	310	49%	UniProt GenBank	DNTP-glucose synthase		Streptomyces globisporus
73	Q9ZA42_STRVN (Q9ZA42)	3e-82	310	51%	UniProt GenBank	Putative dTDP-1-glucose synthase	gra-orf16	Streptomyces violaceoruber
74	D1Z268_METPS (D1Z268)	4e-82	309	46%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rfbA MCP_2718	Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE)
75	O58150_PYRHO (O58150)	4e-82	309	46%	UniProt GenBank	356aa long hypothetical glucose-1-phosphate thymidylyltransferase	PH0413	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
76	D3F2Q7_CONWI (D3F2Q7)	6e-82	308	50%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Cwoe_5787	Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)
77	A5V0R9_ROSS1 (A5V0R9)	1e-81	308	49%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	RoseRS_4128	Roseiflexus sp. (strain RS-1)
78	B7R2B2_9EURY (B7R2B2)	2e-81	307	45%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	TAM4_299	Thermococcus sp. AM4	2.7.7.24 niceE keggE
79	Q27IF8_9ACTO (Q27IF8)	4e-81	306	56%	UniProt GenBank	InkA	inkA	Nonomuraea longicatena
80	Q5QT16_9ACTO (Q5QT16)	4e-81	306	74%	UniProt GenBank	Putative NDP-hexose synthase	staA	Streptomyces longisporoflavus
81	A7NIL1_ROSCS (A7NIL1)	3e-80	303	48%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Rcas_1214	Roseiflexus castenholzii (strain DSM 13941 / HLO8)
82	C4NYL7_9ACTO (C4NYL7)	6e-80	302	47%	UniProt GenBank	SaqG	saqG	Micromonospora sp. Tu 6368
83	F0LLV4_THEBM (F0LLV4)	2e-79	301	45%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	TERMP_02079	Thermococcus barophilus (strain DSM 11836 / MP)
84	Q9UZH3_PYRAB (Q9UZH3)	9e-79	298	45%	UniProt GenBank	Nucleotidyltransferase	graD-3 PYRAB11750 PAB0784	Pyrococcus abyssi (strain GE5 / Orsay)
85	F2KQD5_ARCVS (F2KQD5)	1e-78	298	44%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Arcve_0544	Archaeoglobus veneficus (strain DSM 11195 / SNP6)	2.7.7.24 niceE keggE
86	B7K8G9_CYAP7 (B7K8G9)	1e-78	297	45%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	PCC7424_1488	Cyanothece sp. (strain PCC 7424) Synechococcus sp. (strain ATCC 29155)
87	E0U7Z2_CYAP2 (E0U7Z2)	2e-78	297	44%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Cyan7822_4161	Cyanothece sp. (strain PCC 7822)
88	F8AHY0_9EURY (F8AHY0)	3e-78	296	43%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	PYCH_17780	Pyrococcus yayanosii CH1
89	B5GLJ2_STRCL (B5GLJ2)	3e-78	296	57%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase NDP-1-glucose synthase	SCLAV_p1372 SSCG_00216	Streptomyces clavuligerus ATCC 27064	2.7.7.24 niceE keggE
90	B0BLL5_9ACTO (B0BLL5)	1e-77	295	56%	UniProt GenBank	dTDP-1-glucose synthase	mdpA1	Actinomadura madurae
91	C6A0B0_THESM (C6A0B0)	1e-77	295	46%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	TSIB_2044	Thermococcus sibiricus (strain MM 739 / DSM 12597)	2.7.7.24 niceE keggE
92	Q56174_STRVN (Q56174)	1e-77	294	49%	UniProt GenBank	DTDP-glucose synthetase	graD	Streptomyces violaceoruber
93	Q55689_SYNY3 (Q55689)	2e-77	293	44%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rfbA sll0207	Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1)
94	F7US89_SYNY3 (F7US89)	3e-77	293	44%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rfbA SYNGTS_2253	Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1)
95	D2RDQ5_ARCPA (D2RDQ5)	6e-77	292	43%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Arcpr_1197	Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)
96	D3S215_FERPA (D3S215)	9e-77	291	44%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	Ferp_2391	Ferroglobus placidus (strain DSM 10642 / AEDII12DO)
97	B4W1K2_9CYAN (B4W1K2)	1e-76	291	43%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	MC7420_5159	Microcoleus chthonoplastes PCC 7420	2.7.7.24 niceE keggE
98	B0JFP7_MICAN (B0JFP7)	3e-76	290	44%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	rfbA MAE_00200	Microcystis aeruginosa (strain NIES-843)	2.7.7.24 niceE keggE
99	F4XJ53_9CYAN (F4XJ53)	5e-76	289	44%	UniProt GenBank	Glucose-1-phosphate thymidylyltransferase	LYNGBM3L_08160	Lyngbya majuscula 3L	2.7.7.24 niceE keggE
100	B7JVK5_CYAP8 (B7JVK5)	5e-76	289	44%	UniProt GenBank	Glucose-1-phosphate thymidyltransferase	PCC8801_0480	Cyanothece sp. (strain PCC 8801) Synechococcus sp. (strain PCC 8801 / RF-1)

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q54819_STRPE
(Q54819)

0.0

702

100%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: dnrL
Organism: Streptomyces peucetius

1uniprot[Pubmed] 8932700 [Medline] 97086506
The dnrM gene in Streptomyces peucetius contains a naturally occurring frameshift mutation that is suppressed by another locus outside of the daunorubicin-production gene cluster.(Microbiology)

D9UBR0_STRPR
(D9UBR0)

1e-129

467

69%

Product: Putative dTDP-glucose synthase
Gene: cpp24
Organism: Streptomyces pristinaespiralis

1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]

Q194R4_STRAA
(Q194R4)

1e-126

457

67%

Product: DTDP-glucose synthase
Gene: mtmD
Organism: Streptomyces argillaceus

[pubmed all]
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]

Q7X2H1_9ACTO
(Q7X2H1)

1e-119

432

64%

Product: Putative NDP-glucose synthase
Gene: gilD
Organism: Streptomyces griseoflavus

1uniprot[Pubmed] 12822997 [Medline] 22708304
The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003]

D6MSX8_9ACTO
(D6MSX8)

1e-115

420

61%

Product: SsfS1
Gene: ssfS1
Organism: Streptomyces sp. SF2575

1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]

D1GLU7_9ACTO
(D1GLU7)

1e-114

417

62%

Product: NDP-glucose synthase
Gene: slgS1
Organism: Streptomyces lydicus

1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]

D3Y167_STRPT
(D3Y167)

1e-114

416

62%

Product: Putative glucose-1-phosphate thymidylyltransferase
Gene: strD
Organism: Streptomyces platensis

1uniprot[Pubmed] 20067498
Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010]

B1W377_STRGG
(B1W377)

1e-113

414

60%

Product: Putative glucose-1-phosphate thymidylyltransferase
Gene: strD
SGR_5930
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

D9I0H3_9ACTO
(D9I0H3)

1e-113

412

58%

Product: dTDP-glucose synthase
Gene: cpzDII
Organism: Streptomyces sp. MK730-62F2

1uniprot[Pubmed] 20418426
Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.(Appl. Environ. Microbiol.) [2010]

RMLA_STRGR
(P08075)

1e-112

409

59%

Product: Glucose-1-phosphate thymidylyltransferase
Sugar-nucleotidylation enzyme
dTDP-glucose pyrophosphorylase
dTDP-glucose synthase
Gene: strD
Organism: Streptomyces griseus

1uniprot[Pubmed] 3118332 [Medline] 88040426
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.(Nucleic Acids Res.) [1987]

Q400H3_THECA
(Q400H3)

1e-109

400

58%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: rmlA
Organism: Thermus caldophilus

1uniprot
Biochemical characterization of a novel thermostable glucose-1-phosphate thymidylyltransferase from Thermuscaldophilus: Probing the molecular basis for its unusual thermostability.(Enzyme Microb. Technol.) [2005]

Q83WG7_9ACTO
(Q83WG7)

1e-109

399

62%

Product: Glucose-1-phosphate thymidyltransferase
Gene: staA
Organism: Streptomyces sp. TP-A0274

[pubmed all]
1uniprot Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006]
2uniprot Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006]
3uniprot[Pubmed] 12617516 [Medline] 22504382 Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002]
4uniprot Characterization of the biosynthetic gene cluster of rebecamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003]
5uniprot[Pubmed] 16195595 Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.(Biosci. Biotechnol. Biochem.) [2005]

C9W344_9ACTO
(C9W344)

1e-108

396

60%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: nokF
Organism: Nonomuraea longicatena

1uniprot[Pubmed] 19756308
Molecular cloning, sequence analysis and functional characterization of the gene cluster for biosynthesis of K-252a and its analogs.(Mol. Biosyst.) [2009]

Q76KZ8_STRHA
(Q76KZ8)

1e-108

396

57%

Product: DTDP-glucose synthase
Gene: vinA
Organism: Streptomyces halstedii

1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]

O86865_STRGA
(O86865)

1e-107

394

60%

Product: StrD
Gene: strD
Organism: Streptomyces glaucescens

1uniprot[Pubmed] 8628239 [Medline] 96204519
The str gene cluster for the biosynthesis of 5'-hydroxystreptomycin in Streptomyces glaucescens GLA.0 (ETH 22794): new operons and evidence for pathway-specific regulation by StrR.(Mol. Gen. Genet.) [1996]

2uniprot
Streptomycin Production in Streptomycetes: a Progress Report.(INDUSTRIAL MICROORGANISMS. BASIC AND APPLIED MOLECULAR GENETICS) [1993]

D2B4G8_STRRD
(D2B4G8)

1e-107

393

59%

Product: dTDP-glucose pyrophosphorylase-like protein
Gene: Sros_0631
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

C7G1T7_STRGR
(C7G1T7)

1e-106

389

58%

Product: Putative thymidylyltransferase
Gene
Organism: Streptomyces griseus

1uniprot
Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196.(J. Antibiot.) [2009]

Q9L6C4_STRAT
(Q9L6C4)

1e-105

385

58%

Product: DTDP-D-glucose synthase
Gene
Organism: Streptomyces antibioticus

1uniprot
Mechanism of the 2-deoxygenation step in the biosynthesis of the deoxyhexose moieties of the antibiotics granaticin and oleandomycin.(J. Am. Chem. Soc.) [1999]

Q9RR29_STRAT
(Q9RR29)

1e-104

382

57%

Product: DTDP-D-glucose synthase
Gene: oleS
Organism: Streptomyces antibioticus

1uniprot[Pubmed] 10770761 [Medline] 20233594
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.(Antimicrob. Agents Chemother.) [2000]

Q0RRD1_FRAAA
(Q0RRD1)

1e-103

381

57%

Product: Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)
Gene: FRAAL1228
Organism: Frankia alni (strain ACN14a)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

E9L1G5_9ZZZZ
(E9L1G5)

1e-103

379

55%

Product: Putative uncharacterized protein
Gene: CA37-21
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E9L1R0_9ZZZZ
(E9L1R0)

1e-102

375

55%

Product: Putative uncharacterized protein
Gene: CA915-18
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

A8L9V7_FRASN
(A8L9V7)

1e-101

373

55%

Product: Glucose-1-phosphate thymidyltransferase
Gene: Franean1_5901
Organism: Frankia sp. (strain EAN1pec)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

D2B1Y1_STRRD
(D2B1Y1)

1e-101

372

55%

Product: dTDP-glucose pyrophosphorylase-like protein
Gene: Sros_6491
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

D5SL13_STRCL
(D5SL13)

1e-100

371

57%

Product: Staurosporine biosynthesis glucose-1-phosphate thymidyltransferase StaA
Gene: staA
SCLAV_p1120
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

Q2JF45_FRASC
(Q2JF45)

2e-98

363

54%

Product: Glucose-1-phosphate thymidyltransferase
Gene: Francci3_0713
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

O05171_STRVR
(O05171)

2e-94

350

53%

Product: Putative dTDP glucose synthetase
Gene: aviD
Organism: Streptomyces viridochromogenes

[pubmed all]
1uniprot[Pubmed] 9335272 [Medline] 97474248 Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tu57.(J. Bacteriol.) [1997]
2uniprot[Pubmed] 11410376 [Medline] 21303144 Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics.(Chem. Biol.) [2001]
3uniprot[Pubmed] 15489167 Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.(Chem. Biol.) [2004]

Q52V55_9ACTO
(Q52V55)

4e-94

349

56%

Product: Sugar nucleotidyltransferase
Gene
Organism: Streptomyces aizunensis

1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]

D7C7L4_STRBB
(D7C7L4)

6e-94

348

56%

Product: Glucose-1-phosphate thymidyltransferase
Gene: SBI_09444
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

B0B0U8_STRGA
(B0B0U8)

3e-93

346

52%

Product: dTDP-glucose synthase GacA
Gene: gacA
Organism: Streptomyces glaucescens

1uniprot[Pubmed] 19059289
The gac-gene cluster for the production of acarbose from Streptomyces glaucescens GLA.O: identification, isolation and characterization.(J. Biotechnol.) [2009]

C0JWC0_9ACTO
(C0JWC0)

3e-92

343

54%

Product: PokS1
Gene: pokS1
Organism: Streptomyces diastatochromogenes

1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]

Q0R4N1_STRAT
(Q0R4N1)

1e-89

334

50%

Product: ChlC1
Gene
Organism: Streptomyces antibioticus

1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]

Q2HR55_9ACTO
(Q2HR55)

2e-89

334

49%

Product: Putative dNDP-glucose synthetase
Gene: schS6
Organism: Streptomyces sp. SCC 2136

1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]

2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]

B0LJ32_9ACTO
(B0LJ32)

3e-89

333

50%

Product: Lct49
Gene: lct49
Organism: Streptomyces rishiriensis

1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]

D5ML11_9BACT
(D5ML11)

3e-88

330

51%

Product: Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)
Gene: strD
DAMO_2778
Organism: NC10 bacterium 'Dutch sediment'

1uniprot
Nitrite-driven anaerobic methane oxidation by oxygenic bacteria.(Nature) [2010]

Q0H2X0_9ACTO
(Q0H2X0)

1e-87

328

54%

Product: Putative sugar activating enzyme
Gene: atS7
Organism: Actinomadura melliaura

1uniprot[Pubmed] 16873021
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]

E1IIP0_9CHLR
(E1IIP0)

1e-87

328

51%

Product: Glucose-1-phosphate thymidyltransferase
Gene: OSCT_3191
Organism: Oscillochloris trichoides DG-6

1uniprot[Pubmed] 21037015
Draft genome sequence of the anoxygenic filamentous phototrophic bacterium Oscillochloris trichoides subsp. DG-6.(J. Bacteriol.) [2011]

Q9ZGC8_STRCY
(Q9ZGC8)

1e-87

327

46%

Product: NDP-hexose synthetase homolog
Gene: lanG
Organism: Streptomyces cyanogenus

1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]

Q9RPA6_STRFR
(Q9RPA6)

7e-85

318

48%

Product: DNDP-glucose synthetase
Gene: urdG
Organism: Streptomyces fradiae
Streptomyces roseoflavus

1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]

D7BZS9_STRBB
(D7BZS9)

8e-84

315

48%

Product: Glucose-1-phosphate thymidyltransferase
Gene: SBI_06864
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

Q7WT25_9ACTO
(Q7WT25)

1e-82

311

47%

Product: NDP-1-glucose synthase
Gene: med-ORF18
Organism: Streptomyces sp. AM-7161

1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]

Q8GMI0_STRGL
(Q8GMI0)

3e-82

310

49%

Product: DNTP-glucose synthase
Gene
Organism: Streptomyces globisporus

1uniprot[Pubmed] 12183628 [Medline] 22171413
Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002]

Q9ZA42_STRVN
(Q9ZA42)

3e-82

310

51%

Product: Putative dTDP-1-glucose synthase
Gene: gra-orf16
Organism: Streptomyces violaceoruber

[pubmed all]
1uniprot[Pubmed] 2583128 [Medline] 90060034 Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933 Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446 The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]

O58150_PYRHO
(O58150)

4e-82

309

46%

Product: 356aa long hypothetical glucose-1-phosphate thymidylyltransferase
Gene: PH0413
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

1uniprot[Pubmed] 9679194 [Medline] 98344137
Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.(DNA Res.) [1998]

Q27IF8_9ACTO
(Q27IF8)

4e-81

306

56%

Product: InkA
Gene: inkA
Organism: Nonomuraea longicatena

1uniprot[Pubmed] 17396254
Genetic organization of the biosynthetic gene cluster for the indolocarbazole K-252a in Nonomuraea longicatena JCM 11136.(Appl. Microbiol. Biotechnol.) [2007]

Q5QT16_9ACTO
(Q5QT16)

4e-81

306

74%

Product: Putative NDP-hexose synthase
Gene: staA
Organism: Streptomyces longisporoflavus

1uniprot
Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase.(Mol. Microbiol.) [2005]

C4NYL7_9ACTO
(C4NYL7)

6e-80

302

47%

Product: SaqG
Gene: saqG
Organism: Micromonospora sp. Tu 6368

[pubmed all]
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]

F0LLV4_THEBM
(F0LLV4)

2e-79

301

45%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: TERMP_02079
Organism: Thermococcus barophilus (strain DSM 11836 / MP)

1uniprot[Pubmed] 21217005
Complete genome sequence of the hyperthermophilic, piezophilic, heterotrophic, and carboxydotrophic archaeon Thermococcus barophilus MP.(J. Bacteriol.) [2011]

Q9UZH3_PYRAB
(Q9UZH3)

9e-79

298

45%

Product: Nucleotidyltransferase
Gene: graD-3
PYRAB11750
PAB0784
Organism: Pyrococcus abyssi (strain GE5 / Orsay)

1uniprot[Pubmed] 12622808 [Medline] 22511545
An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi.(Mol. Microbiol.) [2003]

B5GLJ2_STRCL
(B5GLJ2)

3e-78

296

57%

Product: Glucose-1-phosphate thymidyltransferase
NDP-1-glucose synthase
Gene: SCLAV_p1372
SSCG_00216
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

B0BLL5_9ACTO
(B0BLL5)

1e-77

295

56%

Product: dTDP-1-glucose synthase
Gene: mdpA1
Organism: Actinomadura madurae

[pubmed all]
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007]

C6A0B0_THESM
(C6A0B0)

1e-77

295

46%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: TSIB_2044
Organism: Thermococcus sibiricus (strain MM 739 / DSM 12597)

1uniprot[Pubmed] 19447963
Metabolic versatility and indigenous origin of the archaeon Thermococcus sibiricus, isolated from a siberian oil reservoir, as revealed by genome analysis.(Appl. Environ. Microbiol.) [2009]

Q56174_STRVN
(Q56174)

1e-77

294

49%

Product: DTDP-glucose synthetase
Gene: graD
Organism: Streptomyces violaceoruber

1uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]

Q55689_SYNY3
(Q55689)

2e-77

293

44%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: rfbA
sll0207
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1)

1uniprot[Pubmed] 8905231 [Medline] 97061201
Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.(DNA Res.) [1996]

F7US89_SYNY3
(F7US89)

3e-77

293

44%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: rfbA
SYNGTS_2253
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1)

D2RDQ5_ARCPA
(D2RDQ5)

6e-77

292

43%

Product: Glucose-1-phosphate thymidyltransferase
Gene: Arcpr_1197
Organism: Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)

1uniprot
Complete genome sequence of Archaeoglobus profundus type strain (AV18).(Stand. Genomic Sci.) [2010]

B0JFP7_MICAN
(B0JFP7)

3e-76

290

44%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: rfbA
MAE_00200
Organism: Microcystis aeruginosa (strain NIES-843)

1uniprot[Pubmed] 18192279
Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843.(DNA Res.) [2007]

F4XJ53_9CYAN
(F4XJ53)

5e-76

289

44%

Product: Glucose-1-phosphate thymidylyltransferase
Gene: LYNGBM3L_08160
Organism: Lyngbya majuscula 3L

1uniprot
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]