| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
2
|
Q2HR55_9ACTO (Q2HR55) |
|
|
1e-114 |
417 |
58% |
|
- Product
- Putative dNDP-glucose synthetase
- Gene
- schS6
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
3
|
D7BZS9_STRBB (D7BZS9) |
|
|
1e-113 |
412 |
57% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- SBI_06864
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
4
|
Q9ZGC8_STRCY (Q9ZGC8) |
|
|
1e-112 |
408 |
56% |
|
- Product
- NDP-hexose synthetase homolog
- Gene
- lanG
- Organism
- Streptomyces cyanogenus
|
1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999] |
|
5
|
Q0R4N1_STRAT (Q0R4N1) |
|
|
1e-110 |
403 |
56% |
|
- Product
- ChlC1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
6
|
B0LJ32_9ACTO (B0LJ32) |
|
|
1e-109 |
400 |
57% |
|
- Product
- Lct49
- Gene
- lct49
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
8
|
Q9RPA6_STRFR (Q9RPA6) |
|
|
1e-107 |
394 |
55% |
|
- Product
- DNDP-glucose synthetase
- Gene
- urdG
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000] |
|
9
|
Q7WT25_9ACTO (Q7WT25) |
|
|
1e-107 |
393 |
56% |
|
- Product
- NDP-1-glucose synthase
- Gene
- med-ORF18
- Organism
- Streptomyces sp. AM-7161
|
1uniprot Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003] |
|
11
|
Q8GMI0_STRGL (Q8GMI0) |
|
|
1e-106 |
389 |
54% |
|
- Product
- DNTP-glucose synthase
- Gene
-
- Organism
- Streptomyces globisporus
|
1uniprot[Pubmed] 12183628 [Medline] 22171413 Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002] |
|
14
|
D9UBR0_STRPR (D9UBR0) |
|
|
1e-104 |
384 |
53% |
|
- Product
- Putative dTDP-glucose synthase
- Gene
- cpp24
- Organism
- Streptomyces pristinaespiralis
|
1uniprot[Pubmed] 21342465 Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011] |
|
17
|
D9I0H3_9ACTO (D9I0H3) |
|
|
1e-104 |
384 |
52% |
|
- Product
- dTDP-glucose synthase
- Gene
- cpzDII
- Organism
- Streptomyces sp. MK730-62F2
|
1uniprot[Pubmed] 20418426 Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.(Appl. Environ. Microbiol.) [2010] |
|
23
|
Q194R4_STRAA (Q194R4) |
|
|
1e-103 |
379 |
53% |
|
- Product
- DTDP-glucose synthase
- Gene
- mtmD
- Organism
- Streptomyces argillaceus
|
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] | 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] | 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] | 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] | 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] | 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] | 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] | 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] | 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] | 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] | 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] | 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] | 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] | 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] | 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] | 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] | 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] | 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] | 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] | 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] | [pubmed all]
|
24
|
D2B4G8_STRRD (D2B4G8) |
|
|
1e-103 |
379 |
53% |
|
- Product
- dTDP-glucose pyrophosphorylase-like protein
- Gene
- Sros_0631
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
25
|
C4NYL7_9ACTO (C4NYL7) |
|
|
1e-103 |
379 |
55% |
|
- Product
- SaqG
- Gene
- saqG
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
28
|
Q400H3_THECA (Q400H3) |
|
|
1e-102 |
376 |
53% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- rmlA
- Organism
- Thermus caldophilus
|
1uniprot Biochemical characterization of a novel thermostable glucose-1-phosphate thymidylyltransferase from Thermuscaldophilus: Probing the molecular basis for its unusual thermostability.(Enzyme Microb. Technol.) [2005] |
|
30
|
Q76KZ8_STRHA (Q76KZ8) |
|
|
1e-102 |
375 |
51% |
|
- Product
- DTDP-glucose synthase
- Gene
- vinA
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
31
|
Q9L6C4_STRAT (Q9L6C4) |
|
|
1e-101 |
374 |
52% |
|
- Product
- DTDP-D-glucose synthase
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot Mechanism of the 2-deoxygenation step in the biosynthesis of the deoxyhexose moieties of the antibiotics granaticin and oleandomycin.(J. Am. Chem. Soc.) [1999] |
|
32
|
D2B1Y1_STRRD (D2B1Y1) |
|
|
1e-101 |
372 |
52% |
|
- Product
- dTDP-glucose pyrophosphorylase-like protein
- Gene
- Sros_6491
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
34
|
Q9RR29_STRAT (Q9RR29) |
|
|
1e-101 |
372 |
52% |
|
- Product
- DTDP-D-glucose synthase
- Gene
- oleS
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10770761 [Medline] 20233594 Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.(Antimicrob. Agents Chemother.) [2000] |
|
35
|
Q9ZA42_STRVN (Q9ZA42) |
|
|
1e-100 |
370 |
57% |
|
- Product
- Putative dTDP-1-glucose synthase
- Gene
- gra-orf16
- Organism
- Streptomyces violaceoruber
|
1uniprot[Pubmed] 2583128 [Medline] 90060034 Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989] | 2uniprot[Pubmed] 7476861 [Medline] 96027933 Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995] | 3uniprot[Pubmed] 9831526 [Medline] 99051446 The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998] | [pubmed all]
|
36
|
Q83WG7_9ACTO (Q83WG7) |
|
|
1e-100 |
370 |
52% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- staA
- Organism
- Streptomyces sp. TP-A0274
|
1uniprot Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006] | 2uniprot Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006] | 3uniprot[Pubmed] 12617516 [Medline] 22504382 Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002] | 4uniprot Characterization of the biosynthetic gene cluster of rebecamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003] | 5uniprot[Pubmed] 16195595 Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.(Biosci. Biotechnol. Biochem.) [2005] | [pubmed all]
|
39
|
C9W344_9ACTO (C9W344) |
|
|
1e-99 |
367 |
54% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- nokF
- Organism
- Nonomuraea longicatena
|
1uniprot[Pubmed] 19756308 Molecular cloning, sequence analysis and functional characterization of the gene cluster for biosynthesis of K-252a and its analogs.(Mol. Biosyst.) [2009] |
|
40
|
C7G1T7_STRGR (C7G1T7) |
|
|
2e-99 |
367 |
51% |
|
- Product
- Putative thymidylyltransferase
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196.(J. Antibiot.) [2009] |
|
41
|
B1W377_STRGG (B1W377) |
|
|
4e-99 |
366 |
51% |
|
- Product
- Putative glucose-1-phosphate thymidylyltransferase
- Gene
- strD
SGR_5930
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
43
|
D1GLU7_9ACTO (D1GLU7) |
|
|
4e-99 |
365 |
51% |
|
- Product
- NDP-glucose synthase
- Gene
- slgS1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
44
|
Q0H2X0_9ACTO (Q0H2X0) |
|
|
7e-99 |
365 |
55% |
|
- Product
- Putative sugar activating enzyme
- Gene
- atS7
- Organism
- Actinomadura melliaura
|
1uniprot[Pubmed] 16873021 Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006] |
|
48
|
D3Y167_STRPT (D3Y167) |
|
|
1e-97 |
361 |
51% |
|
- Product
- Putative glucose-1-phosphate thymidylyltransferase
- Gene
- strD
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 20067498 Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010] |
|
50
|
D6MSX8_9ACTO (D6MSX8) |
|
|
4e-97 |
359 |
50% |
|
- Product
- SsfS1
- Gene
- ssfS1
- Organism
- Streptomyces sp. SF2575
|
1uniprot[Pubmed] 19908837 Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009] |
|
51
|
C0JWC0_9ACTO (C0JWC0) |
|
|
5e-97 |
359 |
51% |
|
- Product
- PokS1
- Gene
- pokS1
- Organism
- Streptomyces diastatochromogenes
|
1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009] |
|
52
|
RMLA_STRGR (P08075) |
|
|
8e-97 |
358 |
50% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
Sugar-nucleotidylation enzyme dTDP-glucose pyrophosphorylase dTDP-glucose synthase
- Gene
- strD
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 3118332 [Medline] 88040426 Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.(Nucleic Acids Res.) [1987] |
|
53
|
Q7X2H1_9ACTO (Q7X2H1) |
|
|
1e-96 |
357 |
51% |
|
- Product
- Putative NDP-glucose synthase
- Gene
- gilD
- Organism
- Streptomyces griseoflavus
|
1uniprot[Pubmed] 12822997 [Medline] 22708304 The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003] |
|
54
|
Q0RRD1_FRAAA (Q0RRD1) |
|
|
2e-96 |
357 |
50% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)
- Gene
- FRAAL1228
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
55
|
D5SL13_STRCL (D5SL13) |
|
|
3e-96 |
356 |
52% |
|
- Product
- Staurosporine biosynthesis glucose-1-phosphate thymidyltransferase StaA
- Gene
- staA
SCLAV_p1120
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
57
|
Q83X52_STRRO (Q83X52) |
|
|
1e-95 |
354 |
54% |
|
- Product
- Putative NDP-glucose synthase
- Gene
- lkmU
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|
58
|
A8L9V7_FRASN (A8L9V7) |
|
|
2e-95 |
353 |
50% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- Franean1_5901
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
59
|
Q2JF45_FRASC (Q2JF45) |
|
|
2e-95 |
353 |
50% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- Francci3_0713
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
60
|
E9L1R0_9ZZZZ (E9L1R0) |
|
|
3e-95 |
353 |
49% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-18
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
61
|
Q56174_STRVN (Q56174) |
|
|
5e-95 |
352 |
55% |
|
- Product
- DTDP-glucose synthetase
- Gene
- graD
- Organism
- Streptomyces violaceoruber
|
1uniprot[Pubmed] 7476861 [Medline] 96027933 Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995] |
|
63
|
O05171_STRVR (O05171) |
|
|
4e-94 |
349 |
49% |
|
- Product
- Putative dTDP glucose synthetase
- Gene
- aviD
- Organism
- Streptomyces viridochromogenes
|
1uniprot[Pubmed] 9335272 [Medline] 97474248 Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tu57.(J. Bacteriol.) [1997] | 2uniprot[Pubmed] 11410376 [Medline] 21303144 Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics.(Chem. Biol.) [2001] | 3uniprot[Pubmed] 15489167 Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.(Chem. Biol.) [2004] | [pubmed all]
|
64
|
E9L1G5_9ZZZZ (E9L1G5) |
|
|
2e-93 |
347 |
48% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-21
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
65
|
D5ML11_9BACT (D5ML11) |
|
|
3e-92 |
343 |
47% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase (DTDP-glucose synthase) (DTDP-glucose pyrophosphorylase) (Sugar-nucleotidylation enzyme)
- Gene
- strD
DAMO_2778
- Organism
- NC10 bacterium 'Dutch sediment'
|
1uniprot Nitrite-driven anaerobic methane oxidation by oxygenic bacteria.(Nature) [2010] |
|
66
|
D7C7L4_STRBB (D7C7L4) |
|
|
6e-92 |
342 |
51% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- SBI_09444
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
67
|
B0B0U8_STRGA (B0B0U8) |
|
|
7e-92 |
342 |
51% |
|
- Product
- dTDP-glucose synthase GacA
- Gene
- gacA
- Organism
- Streptomyces glaucescens
|
1uniprot[Pubmed] 19059289 The gac-gene cluster for the production of acarbose from Streptomyces glaucescens GLA.O: identification, isolation and characterization.(J. Biotechnol.) [2009] |
|
68
|
O86865_STRGA (O86865) |
|
|
2e-91 |
340 |
50% |
|
- Product
- StrD
- Gene
- strD
- Organism
- Streptomyces glaucescens
|
1uniprot[Pubmed] 8628239 [Medline] 96204519 The str gene cluster for the biosynthesis of 5'-hydroxystreptomycin in Streptomyces glaucescens GLA.0 (ETH 22794): new operons and evidence for pathway-specific regulation by StrR.(Mol. Gen. Genet.) [1996] | 2uniprot Streptomycin Production in Streptomycetes: a Progress Report.(INDUSTRIAL MICROORGANISMS. BASIC AND APPLIED MOLECULAR GENETICS) [1993] |
|
69
|
Q4R0L8_STRCX (Q4R0L8) |
|
|
2e-91 |
340 |
53% |
|
- Product
- ChaS1 protein
- Gene
- chaS1
- Organism
- Streptomyces chartreusis
|
1uniprot[Pubmed] 15911378 Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005] |
|
70
|
B5GLJ2_STRCL (B5GLJ2) |
|
|
6e-90 |
335 |
54% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
NDP-1-glucose synthase
- Gene
- SCLAV_p1372
SSCG_00216
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
73
|
B0JFP7_MICAN (B0JFP7) |
|
|
3e-88 |
330 |
46% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- rfbA
MAE_00200
- Organism
- Microcystis aeruginosa (strain NIES-843)
|
1uniprot[Pubmed] 18192279 Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843.(DNA Res.) [2007] |
|
75
|
B1WSB1_CYAA5 (B1WSB1) |
|
|
4e-88 |
329 |
45% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- rfbA
cce_2549
- Organism
- Cyanothece sp. (strain ATCC 51142)
|
1uniprot[Pubmed] 18812508 The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
76
|
C8W2E1_DESAS (C8W2E1) |
|
|
6e-88 |
328 |
46% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- Dtox_2860
- Organism
- Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644)
|
1uniprot[Pubmed] 21304664 Complete genome sequence of Desulfotomaculum acetoxidans type strain (5575).(Stand. Genomic Sci.) [2009] |
|
82
|
Q52V55_9ACTO (Q52V55) |
|
|
2e-87 |
327 |
50% |
|
- Product
- Sugar nucleotidyltransferase
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
84
|
Q2PC36_STRAH (Q2PC36) |
|
|
4e-87 |
326 |
51% |
|
- Product
- Putative TDP-glucose synthase
- Gene
- rubN1
- Organism
- Streptomyces achromogenes subsp. rubradiris
|
1uniprot[Pubmed] 9387157 [Medline] 98048398 Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997] | 2uniprot[Pubmed] 12889805 [Medline] 22771458 Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003] | [pubmed all]
|
89
|
E1IIP0_9CHLR (E1IIP0) |
|
|
1e-86 |
324 |
46% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- OSCT_3191
- Organism
- Oscillochloris trichoides DG-6
|
1uniprot[Pubmed] 21037015 Draft genome sequence of the anoxygenic filamentous phototrophic bacterium Oscillochloris trichoides subsp. DG-6.(J. Bacteriol.) [2011] |
|
91
|
Q8YNS0_NOSS1 (Q8YNS0) |
|
|
3e-86 |
323 |
46% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- alr4491
- Organism
- Nostoc sp. (strain PCC 7120 / UTEX 2576)
|
1uniprot[Pubmed] 11759840 [Medline] 21595285 Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120.(DNA Res.) [2001] |
|
92
|
B0BLL5_9ACTO (B0BLL5) |
|
|
4e-86 |
323 |
53% |
|
- Product
- dTDP-1-glucose synthase
- Gene
- mdpA1
- Organism
- Actinomadura madurae
|
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003] | 2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007] | [pubmed all]
|
94
|
C7LY75_ACIFD (C7LY75) |
|
|
1e-85 |
321 |
51% |
|
- Product
- Glucose-1-phosphate thymidyltransferase
- Gene
- Afer_0733
- Organism
- Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)
|
1uniprot Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICP).(Stand. Genomic Sci.) [2009] |
|
99
|
Q3ADG1_CARHZ (Q3ADG1) |
|
|
3e-85 |
320 |
43% |
|
- Product
- Glucose-1-phosphate thymidylyltransferase
- Gene
- CHY_0976
- Organism
- Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
|
1uniprot[Pubmed] 16311624 Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901.(PLoS Genet.) [2005] |
|