BLAST table : Tauto_00110

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 C0SMW4_9ACTO
(C0SMW4)		 
[query] 1 - 10827 (10827)
[subject] 1 - 10827 (10827)
 0.0 21100   100% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
2
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 3 - 9270 (10827)
[subject] 436 - 9487 (9528)
(17 hsp)		 0.0 10490   64% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
3
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 3 - 9270 (10827)
[subject] 552 - 9607 (9648)
(16 hsp)		 0.0 10490   64% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
4
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 5490 - 10160 (10827)
[subject] 34 - 4680 (5770)
(19 hsp)		 0.0 5909   69% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
5
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 3796 - 10159 (10827)
[subject] 29 - 6452 (10917)
(29 hsp)		 0.0 5395   51% AmphC amphC Streptomyces nodosus
6
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 2283 - 8573 (10827)
[subject] 34 - 6380 (6831)
(19 hsp)		 0.0 5303   51% ScnS1 scnS1 Streptomyces chattanoogensis
7
 Q82QT4_STRAW
(Q82QT4)		 
[query] 2175 - 8572 (10827)
[subject] 941 - 7290 (7746)
(28 hsp)		 0.0 5258   50% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
8
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 2283 - 8576 (10827)
[subject] 34 - 6349 (6797)
(19 hsp)		 0.0 5256   51% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
9
 D9T6W4_MICAI
(D9T6W4)		 
[query] 2281 - 8572 (10827)
[subject] 33 - 6452 (9936)
(31 hsp)		 0.0 5227   51% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
10
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 458 - 7180 (10827)
[subject] 1617 - 8224 (8301)
(27 hsp)		 0.0 5214   51% Type I polyketide synthase sfaH Streptomyces flaveolus
11
 E8S0C5_MICSL
(E8S0C5)		 
[query] 2281 - 8572 (10827)
[subject] 33 - 6452 (9937)
(31 hsp)		 0.0 5212   50% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
12
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 3796 - 10159 (10827)
[subject] 29 - 6452 (10876)
(30 hsp)		 0.0 5144   51% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
13
 E0KFI7_STRVO
(E0KFI7)		 
[query] 552 - 6376 (10827)
[subject] 24 - 6000 (8538)
(26 hsp)		 0.0 5143   51% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
14
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 453 - 6363 (10827)
[subject] 3142 - 9198 (10873)
(37 hsp)		 0.0 5053   51% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
15
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1818 - 8581 (10827)
[subject] 2883 - 9912 (14130)
(38 hsp)		 0.0 4958   44% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
16
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 3791 - 10161 (10827)
[subject] 23 - 6106 (6260)
(21 hsp)		 0.0 4848   48% Polyketide synthase rapC Streptomyces hygroscopicus
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 3784 - 10158 (10827)
[subject] 17 - 6060 (10223)
(29 hsp)		 0.0 4784   48% Polyketide synthase rapB Streptomyces hygroscopicus
18
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1818 - 8378 (10827)
[subject] 2876 - 9714 (12352)
(39 hsp)		 0.0 4772   44% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
19
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 3802 - 10158 (10827)
[subject] 18 - 6646 (16990)
(42 hsp)		 0.0 4590   44% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
20
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 3802 - 10158 (10827)
[subject] 18 - 6644 (17019)
(49 hsp)		 0.0 4554   44% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
21
 D7CC08_STRBB
(D7CC08)		 
[query] 5491 - 10782 (10827)
[subject] 34 - 5431 (5530)
(17 hsp)		 0.0 4519   52% Putative type I polyketide synthase pks5-2
SBI_01382		 Streptomyces bingchenggensis (strain BCW-1)
22
 E0L044_STRVO
(E0L044)		 
[query] 3311 - 8585 (10827)
[subject] 1362 - 6783 (7224)
(27 hsp)		 0.0 4383   50% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
23
 B5M9K9_STRLS
(B5M9K9)		 Jump to Lasal2_00170 
[query] 5491 - 10786 (10827)
[subject] 34 - 5377 (5469)
(15 hsp)		 0.0 4335   49% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
24
 B6ZK65_STRLS
(B6ZK65)		 Jump to Lasal_00140 
[query] 5498 - 10786 (10827)
[subject] 1 - 5337 (5429)
(16 hsp)		 0.0 4329   49% Putative polyketide synthase lsd12 Streptomyces lasaliensis
25
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 5491 - 10160 (10827)
[subject] 63 - 4650 (7488)
(26 hsp)		 0.0 4223   54% ObsC Saccharopolyspora spinosa
26
 D7BRD4_STRBB
(D7BRD4)		 
[query] 3324 - 8572 (10827)
[subject] 4123 - 9497 (9950)
(33 hsp)		 0.0 4221   50% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
27
 E0L075_STRVO
(E0L075)		 
[query] 5491 - 10164 (10827)
[subject] 34 - 4766 (5786)
(24 hsp)		 0.0 4188   52% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
28
 Q52V53_9ACTO
(Q52V53)		 
[query] 2283 - 7181 (10827)
[subject] 34 - 5128 (5207)
(16 hsp)		 0.0 4158   50% Polyketide synthase type I Streptomyces aizunensis
29
 Q93H87_STRAW
(Q93H87)		 
[query] 2175 - 7176 (10827)
[subject] 941 - 5959 (6048)
(24 hsp)		 0.0 4148   50% Modular polyketide synthase pteA1 Streptomyces avermitilis
30
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 1909 - 5131 (10827)
[subject] 1704 - 4948 (5710)
(22 hsp)		 0.0 4137   69% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
31
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 3798 - 8534 (10827)
[subject] 15 - 4851 (4894)
(15 hsp)		 0.0 4130   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
32
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 5142 - 10158 (10827)
[subject] 2928 - 7693 (8563)
(30 hsp)		 0.0 4095   50% Polyketide synthase rapA Streptomyces hygroscopicus
33
 Q52V50_9ACTO
(Q52V50)		 
[query] 5491 - 10160 (10827)
[subject] 39 - 4804 (7510)
(22 hsp)		 0.0 4069   51% Polyketide synthase type I Streptomyces aizunensis
34
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 3324 - 8522 (10827)
[subject] 1327 - 6533 (10625)
(38 hsp)		 0.0 4050   50% FscC fscC Streptomyces sp. FR-008
35
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 448 - 5482 (10827)
[subject] 1727 - 7003 (7026)
(23 hsp)		 0.0 4044   48% Polyketide synthase pldAII Streptomyces platensis
36
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 5480 - 10160 (10827)
[subject] 30 - 4707 (5644)
(21 hsp)		 0.0 4004   51% AmphJ amphJ Streptomyces nodosus
37
 D7P611_CHOCO
(D7P611)		 
[query] 4245 - 9259 (10827)
[subject] 988 - 6154 (6255)
(27 hsp)		 0.0 4003   48% TugA tugA Chondromyces crocatus
38
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 3324 - 8572 (10827)
[subject] 1420 - 6666 (7110)
(25 hsp)		 0.0 3998   49% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
39
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 5491 - 10158 (10827)
[subject] 39 - 4486 (5723)
(23 hsp)		 0.0 3997   52% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
40
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3802 - 8569 (10827)
[subject] 34 - 4917 (5588)
(15 hsp)		 0.0 3979   50% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
41
 A4X8L0_SALTO
(A4X8L0)		 
[query] 3349 - 8569 (10827)
[subject] 1460 - 6752 (7210)
(23 hsp)		 0.0 3976   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
42
 E0KFI9_STRVO
(E0KFI9)		 
[query] 1818 - 6365 (10827)
[subject] 1212 - 5914 (8238)
(29 hsp)		 0.0 3969   52% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
43
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 557 - 5140 (10827)
[subject] 28 - 4623 (7102)
(24 hsp)		 0.0 3968   51% Polyketide synthase merB Streptomyces sp. NRRL 30748
44
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 2283 - 7186 (10827)
[subject] 34 - 5138 (5220)
(19 hsp)		 0.0 3949   49% Type I polyketide synthase hlsC Streptomyces halstedii
45
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 3808 - 8388 (10827)
[subject] 41 - 4673 (11096)
(38 hsp)		 0.0 3942   52% NysC nysC Streptomyces noursei
46
 Q52V46_9ACTO
(Q52V46)		 
[query] 1818 - 6363 (10827)
[subject] 1208 - 5882 (8147)
(31 hsp)		 0.0 3866   51% Polyketide synthase type I Streptomyces aizunensis
47
 A8M6C7_SALAI
(A8M6C7)		 
[query] 3802 - 8591 (10827)
[subject] 35 - 4830 (5255)
(16 hsp)		 0.0 3862   51% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
48
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2283 - 6817 (10827)
[subject] 34 - 4736 (7111)
(25 hsp)		 0.0 3837   51% Type I polyketide synthase hlsB Streptomyces halstedii
49
 B1W485_STRGG
(B1W485)		 
[query] 556 - 5469 (10827)
[subject] 28 - 5049 (5136)
(16 hsp)		 0.0 3834   49% Putative type-I PKS pks1-1
SGR_6073		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
50
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 3681 - 8583 (10827)
[subject] 903 - 5809 (6241)
(24 hsp)		 0.0 3807   49% Polyketide synthase KijS1 Actinomadura kijaniata
51
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 3802 - 8572 (10827)
[subject] 35 - 4886 (5339)
(16 hsp)		 0.0 3798   49% Polyketide synthase natB Streptomyces sp. CS
52
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 6824 - 10160 (10827)
[subject] 1732 - 4990 (7620)
(27 hsp)		 0.0 3796   64% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
53
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 3710 - 8596 (10827)
[subject] 901 - 5625 (6078)
(23 hsp)		 0.0 3790   50% ObsA Saccharopolyspora spinosa
54
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 557 - 5140 (10827)
[subject] 28 - 4699 (7178)
(24 hsp)		 0.0 3789   50% MerB merB Streptomyces violaceoniger
55
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3802 - 8571 (10827)
[subject] 34 - 4658 (5099)
(17 hsp)		 0.0 3782   50% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
56
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 3802 - 8572 (10827)
[subject] 35 - 4643 (5060)
(16 hsp)		 0.0 3780   50% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
57
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 3802 - 8572 (10827)
[subject] 35 - 4643 (5060)
(16 hsp)		 0.0 3778   50% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
58
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 6824 - 10160 (10827)
[subject] 1690 - 4944 (7576)
(27 hsp)		 0.0 3778   64% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
59
 O52789_AMYMD
(O52789)		 
[query] 3802 - 8572 (10827)
[subject] 44 - 4652 (5069)
(16 hsp)		 0.0 3777   50% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
60
 Q52V52_9ACTO
(Q52V52)		 
[query] 3803 - 8572 (10827)
[subject] 35 - 4961 (5432)
(16 hsp)		 0.0 3763   49% Polyketide synthase type I Streptomyces aizunensis
61
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 3796 - 8571 (10827)
[subject] 29 - 4738 (5176)
(17 hsp)		 0.0 3762   49% ObsB Saccharopolyspora spinosa
62
 B5L6K9_MICCH
(B5L6K9)		 
[query] 3136 - 8583 (10827)
[subject] 1086 - 6569 (7007)
(21 hsp)		 0.0 3700   45% Putative type I polyketide synthase Micromonospora chalcea
63
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 3801 - 8574 (10827)
[subject] 30 - 4865 (5321)
(18 hsp)		 0.0 3686   49% Polyketide synthase natC Streptomyces sp. CS
64
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 3795 - 8586 (10827)
[subject] 31 - 5081 (5532)
(17 hsp)		 0.0 3685   48% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
65
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 557 - 4679 (10827)
[subject] 28 - 4214 (9498)
(38 hsp)		 0.0 3684   53% ScnS2 scnS2 Streptomyces chattanoogensis
66
 D7C2B8_STRBB
(D7C2B8)		 
[query] 5138 - 9282 (10827)
[subject] 3258 - 7428 (7498)
(27 hsp)		 0.0 3681   52% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
67
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 557 - 4670 (10827)
[subject] 28 - 4198 (9510)
(39 hsp)		 0.0 3661   53% AmphI amphI Streptomyces nodosus
68
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 3685 - 8572 (10827)
[subject] 900 - 5921 (6383)
(24 hsp)		 0.0 3657   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
69
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 3802 - 8562 (10827)
[subject] 39 - 4733 (5400)
(19 hsp)		 0.0 3639   49% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
70
 E0KBI2_STRVO
(E0KBI2)		 
[query] 552 - 4679 (10827)
[subject] 22 - 4204 (4930)
(21 hsp)		 0.0 3625   52% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
71
 D7C2C3_STRBB
(D7C2C3)		 
[query] 557 - 4677 (10827)
[subject] 28 - 4325 (4868)
(18 hsp)		 0.0 3621   52% Modular polyketide synthase pks3-4
SBI_00656		 Streptomyces bingchenggensis (strain BCW-1)
72
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 2191 - 6363 (10827)
[subject] 971 - 5049 (5712)
(24 hsp)		 0.0 3613   52% Polyketide synthase merA Streptomyces sp. NRRL 30748
73
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 557 - 4677 (10827)
[subject] 28 - 4212 (9507)
(38 hsp)		 0.0 3608   52% PimS2 protein pimS2 Streptomyces natalensis
74
 B5L6K8_MICCH
(B5L6K8)		 
[query] 3701 - 8569 (10827)
[subject] 919 - 5855 (6305)
(21 hsp)		 0.0 3603   45% Putative type I polyketide synthase Micromonospora chalcea
75
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 5000 - 9259 (10827)
[subject] 2050 - 6445 (6532)
(27 hsp)		 0.0 3596   50% Polyketide synthase pldAI Streptomyces platensis
76
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 3802 - 8095 (10827)
[subject] 34 - 4510 (5232)
(16 hsp)		 0.0 3563   50% Type I polyketide synthase hlsF Streptomyces halstedii
77
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 3729 - 8655 (10827)
[subject] 55 - 4969 (5260)
(16 hsp)		 0.0 3561   46% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
78
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 2178 - 6363 (10827)
[subject] 968 - 5051 (5721)
(24 hsp)		 0.0 3554   51% MerA merA Streptomyces violaceoniger
79
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 3796 - 8088 (10827)
[subject] 28 - 4475 (5214)
(20 hsp)		 0.0 3523   50% Polyketide synthase idmN Streptomyces antibioticus
80
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 556 - 4670 (10827)
[subject] 27 - 4242 (9477)
(39 hsp)		 0.0 3516   52% NysI nysI Streptomyces noursei
81
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 3428 - 8397 (10827)
[subject] 2430 - 7109 (7525)
(22 hsp)		 0.0 3508   47% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
82
 A8LUX2_SALAI
(A8LUX2)		 
[query] 448 - 4670 (10827)
[subject] 2552 - 6619 (7279)
(27 hsp)		 0.0 3506   51% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
83
 F8JVX1_STRCT
(F8JVX1)		 
[query] 3703 - 8089 (10827)
[subject] 945 - 5402 (6125)
(21 hsp)		 0.0 3505   48% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
84
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 3802 - 8585 (10827)
[subject] 34 - 4725 (5157)
(17 hsp)		 0.0 3504   48% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
85
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 3425 - 8591 (10827)
[subject] 2792 - 7523 (7938)
(26 hsp)		 0.0 3499   46% Polyketide synthase rapA Actinoplanes sp. N902-109
86
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 557 - 4670 (10827)
[subject] 33 - 4220 (9550)
(39 hsp)		 0.0 3497   52% FscD fscD Streptomyces sp. FR-008
87
 E8WEN5_STRFA
(E8WEN5)		 
[query] 3802 - 8583 (10827)
[subject] 34 - 4726 (5156)
(17 hsp)		 0.0 3488   48% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
88
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 3688 - 8222 (10827)
[subject] 904 - 5577 (5582)
(21 hsp)		 0.0 3488   46% Polyketide synthase type I becA Streptomyces sp. DSM 21069
89
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 557 - 4673 (10827)
[subject] 28 - 4221 (9499)
(37 hsp)		 0.0 3470   52% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
90
 Q52V44_9ACTO
(Q52V44)		 
[query] 557 - 4671 (10827)
[subject] 29 - 4225 (6751)
(25 hsp)		 0.0 3453   51% Polyketide synthase type I Streptomyces aizunensis
91
 F8JUL0_STRCT
(F8JUL0)		 
[query] 3696 - 8220 (10827)
[subject] 927 - 5432 (5950)
(28 hsp)		 0.0 3444   49% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
92
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 3709 - 7858 (10827)
[subject] 892 - 4978 (5113)
(24 hsp)		 0.0 3437   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
93
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 3795 - 8099 (10827)
[subject] 29 - 4409 (5136)
(16 hsp)		 0.0 3413   47% Polyketide synthase tsnAII Streptomyces longisporoflavus
94
 E9KTB8_STRKN
(E9KTB8)		 
[query] 5138 - 10174 (10827)
[subject] 1556 - 6275 (6408)
(23 hsp)		 0.0 3409   45% Polyketide synthase fkbA
Tcs_SK_034		 Streptomyces kanamyceticus
95
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 559 - 4670 (10827)
[subject] 34 - 4209 (4928)
(21 hsp)		 0.0 3407   51% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
96
 E9KTB5_STRKN
(E9KTB5)		 
[query] 3428 - 8379 (10827)
[subject] 2452 - 7145 (7591)
(25 hsp)		 0.0 3407   46% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
97
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 5138 - 10158 (10827)
[subject] 1557 - 6264 (6418)
(25 hsp)		 0.0 3402   45% Polyketide synthase fkbA
Tcs_11604BP_031		 Streptomyces sp. KCTC 11604BP
98
 F1D8Z9_9ACTO
(F1D8Z9)		 
[query] 5138 - 10158 (10827)
[subject] 1557 - 6264 (6418)
(25 hsp)		 0.0 3400   45% FkbA Streptomyces sp. MJM7001
99
 A0ACH3_STRAM
(A0ACH3)		 
[query] 44 - 4672 (10827)
[subject] 473 - 5107 (5771)
(21 hsp)		 0.0 3368   48% Putative type I polyketide synthase SAMR0467 Streptomyces ambofaciens ATCC 23877
100
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 6824 - 10782 (10827)
[subject] 2805 - 6769 (6855)
(23 hsp)		 0.0 3359   50% GelA Streptomyces hygroscopicus subsp. duamyceticus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 C0SMW4_9ACTO
(C0SMW4)		 
[query] 1 - 10827 (10827)
[subject] 1 - 10827 (10827)
 0.0 21100   100%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
2
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 3 - 9270 (10827)
[subject] 436 - 9487 (9528)
(17 hsp)		 0.0 10490   64%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
3
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 3 - 9270 (10827)
[subject] 552 - 9607 (9648)
(16 hsp)		 0.0 10490   64%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
4
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 5490 - 10160 (10827)
[subject] 34 - 4680 (5770)
(19 hsp)		 0.0 5909   69%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
5
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 3796 - 10159 (10827)
[subject] 29 - 6452 (10917)
(29 hsp)		 0.0 5395   51%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
6
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 2283 - 8573 (10827)
[subject] 34 - 6380 (6831)
(19 hsp)		 0.0 5303   51%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
7
 Q82QT4_STRAW
(Q82QT4)		 
[query] 2175 - 8572 (10827)
[subject] 941 - 7290 (7746)
(28 hsp)		 0.0 5258   50%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
8
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 2283 - 8576 (10827)
[subject] 34 - 6349 (6797)
(19 hsp)		 0.0 5256   51%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
10
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 458 - 7180 (10827)
[subject] 1617 - 8224 (8301)
(27 hsp)		 0.0 5214   51%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
12
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 3796 - 10159 (10827)
[subject] 29 - 6452 (10876)
(30 hsp)		 0.0 5144   51%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
15
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1818 - 8581 (10827)
[subject] 2883 - 9912 (14130)
(38 hsp)		 0.0 4958   44%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
16
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 3791 - 10161 (10827)
[subject] 23 - 6106 (6260)
(21 hsp)		 0.0 4848   48%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 3784 - 10158 (10827)
[subject] 17 - 6060 (10223)
(29 hsp)		 0.0 4784   48%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
18
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1818 - 8378 (10827)
[subject] 2876 - 9714 (12352)
(39 hsp)		 0.0 4772   44%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
19
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 3802 - 10158 (10827)
[subject] 18 - 6646 (16990)
(42 hsp)		 0.0 4590   44%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
20
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 3802 - 10158 (10827)
[subject] 18 - 6644 (17019)
(49 hsp)		 0.0 4554   44%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
21
 D7CC08_STRBB
(D7CC08)		 
[query] 5491 - 10782 (10827)
[subject] 34 - 5431 (5530)
(17 hsp)		 0.0 4519   52%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
24
 B6ZK65_STRLS
(B6ZK65)		 Jump to Lasal_00140 
[query] 5498 - 10786 (10827)
[subject] 1 - 5337 (5429)
(16 hsp)		 0.0 4329   49%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
25
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 5491 - 10160 (10827)
[subject] 63 - 4650 (7488)
(26 hsp)		 0.0 4223   54%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
26
 D7BRD4_STRBB
(D7BRD4)		 
[query] 3324 - 8572 (10827)
[subject] 4123 - 9497 (9950)
(33 hsp)		 0.0 4221   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
28
 Q52V53_9ACTO
(Q52V53)		 
[query] 2283 - 7181 (10827)
[subject] 34 - 5128 (5207)
(16 hsp)		 0.0 4158   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
29
 Q93H87_STRAW
(Q93H87)		 
[query] 2175 - 7176 (10827)
[subject] 941 - 5959 (6048)
(24 hsp)		 0.0 4148   50%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
30
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 1909 - 5131 (10827)
[subject] 1704 - 4948 (5710)
(22 hsp)		 0.0 4137   69%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
32
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 5142 - 10158 (10827)
[subject] 2928 - 7693 (8563)
(30 hsp)		 0.0 4095   50%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
33
 Q52V50_9ACTO
(Q52V50)		 
[query] 5491 - 10160 (10827)
[subject] 39 - 4804 (7510)
(22 hsp)		 0.0 4069   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
34
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 3324 - 8522 (10827)
[subject] 1327 - 6533 (10625)
(38 hsp)		 0.0 4050   50%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
35
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 448 - 5482 (10827)
[subject] 1727 - 7003 (7026)
(23 hsp)		 0.0 4044   48%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
36
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 5480 - 10160 (10827)
[subject] 30 - 4707 (5644)
(21 hsp)		 0.0 4004   51%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
37
 D7P611_CHOCO
(D7P611)		 
[query] 4245 - 9259 (10827)
[subject] 988 - 6154 (6255)
(27 hsp)		 0.0 4003   48%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
38
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 3324 - 8572 (10827)
[subject] 1420 - 6666 (7110)
(25 hsp)		 0.0 3998   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
39
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 5491 - 10158 (10827)
[subject] 39 - 4486 (5723)
(23 hsp)		 0.0 3997   52%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
40
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3802 - 8569 (10827)
[subject] 34 - 4917 (5588)
(15 hsp)		 0.0 3979   50%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
43
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 557 - 5140 (10827)
[subject] 28 - 4623 (7102)
(24 hsp)		 0.0 3968   51%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
45
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 3808 - 8388 (10827)
[subject] 41 - 4673 (11096)
(38 hsp)		 0.0 3942   52%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
46
 Q52V46_9ACTO
(Q52V46)		 
[query] 1818 - 6363 (10827)
[subject] 1208 - 5882 (8147)
(31 hsp)		 0.0 3866   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
48
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2283 - 6817 (10827)
[subject] 34 - 4736 (7111)
(25 hsp)		 0.0 3837   51%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
49
 B1W485_STRGG
(B1W485)		 
[query] 556 - 5469 (10827)
[subject] 28 - 5049 (5136)
(16 hsp)		 0.0 3834   49%
Product
Putative type-I PKS
Gene
pks1-1
SGR_6073
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
50
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 3681 - 8583 (10827)
[subject] 903 - 5809 (6241)
(24 hsp)		 0.0 3807   49%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
51
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 3802 - 8572 (10827)
[subject] 35 - 4886 (5339)
(16 hsp)		 0.0 3798   49%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
52
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 6824 - 10160 (10827)
[subject] 1732 - 4990 (7620)
(27 hsp)		 0.0 3796   64%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
53
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 3710 - 8596 (10827)
[subject] 901 - 5625 (6078)
(23 hsp)		 0.0 3790   50%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
54
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 557 - 5140 (10827)
[subject] 28 - 4699 (7178)
(24 hsp)		 0.0 3789   50%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
55
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3802 - 8571 (10827)
[subject] 34 - 4658 (5099)
(17 hsp)		 0.0 3782   50%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
56
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 3802 - 8572 (10827)
[subject] 35 - 4643 (5060)
(16 hsp)		 0.0 3780   50%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
57
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 3802 - 8572 (10827)
[subject] 35 - 4643 (5060)
(16 hsp)		 0.0 3778   50%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
58
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 6824 - 10160 (10827)
[subject] 1690 - 4944 (7576)
(27 hsp)		 0.0 3778   64%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
60
 Q52V52_9ACTO
(Q52V52)		 
[query] 3803 - 8572 (10827)
[subject] 35 - 4961 (5432)
(16 hsp)		 0.0 3763   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
61
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 3796 - 8571 (10827)
[subject] 29 - 4738 (5176)
(17 hsp)		 0.0 3762   49%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
62
 B5L6K9_MICCH
(B5L6K9)		 
[query] 3136 - 8583 (10827)
[subject] 1086 - 6569 (7007)
(21 hsp)		 0.0 3700   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
63
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 3801 - 8574 (10827)
[subject] 30 - 4865 (5321)
(18 hsp)		 0.0 3686   49%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
64
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 3795 - 8586 (10827)
[subject] 31 - 5081 (5532)
(17 hsp)		 0.0 3685   48%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
65
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 557 - 4679 (10827)
[subject] 28 - 4214 (9498)
(38 hsp)		 0.0 3684   53%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
66
 D7C2B8_STRBB
(D7C2B8)		 
[query] 5138 - 9282 (10827)
[subject] 3258 - 7428 (7498)
(27 hsp)		 0.0 3681   52%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
67
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 557 - 4670 (10827)
[subject] 28 - 4198 (9510)
(39 hsp)		 0.0 3661   53%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
68
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 3685 - 8572 (10827)
[subject] 900 - 5921 (6383)
(24 hsp)		 0.0 3657   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
69
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 3802 - 8562 (10827)
[subject] 39 - 4733 (5400)
(19 hsp)		 0.0 3639   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
71
 D7C2C3_STRBB
(D7C2C3)		 
[query] 557 - 4677 (10827)
[subject] 28 - 4325 (4868)
(18 hsp)		 0.0 3621   52%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
72
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 2191 - 6363 (10827)
[subject] 971 - 5049 (5712)
(24 hsp)		 0.0 3613   52%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
73
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 557 - 4677 (10827)
[subject] 28 - 4212 (9507)
(38 hsp)		 0.0 3608   52%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
74
 B5L6K8_MICCH
(B5L6K8)		 
[query] 3701 - 8569 (10827)
[subject] 919 - 5855 (6305)
(21 hsp)		 0.0 3603   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
75
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 5000 - 9259 (10827)
[subject] 2050 - 6445 (6532)
(27 hsp)		 0.0 3596   50%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
78
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 2178 - 6363 (10827)
[subject] 968 - 5051 (5721)
(24 hsp)		 0.0 3554   51%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
79
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 3796 - 8088 (10827)
[subject] 28 - 4475 (5214)
(20 hsp)		 0.0 3523   50%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
80
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 556 - 4670 (10827)
[subject] 27 - 4242 (9477)
(39 hsp)		 0.0 3516   52%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
81
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 3428 - 8397 (10827)
[subject] 2430 - 7109 (7525)
(22 hsp)		 0.0 3508   47%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
86
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 557 - 4670 (10827)
[subject] 33 - 4220 (9550)
(39 hsp)		 0.0 3497   52%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
88
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 3688 - 8222 (10827)
[subject] 904 - 5577 (5582)
(21 hsp)		 0.0 3488   46%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
89
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 557 - 4673 (10827)
[subject] 28 - 4221 (9499)
(37 hsp)		 0.0 3470   52%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
90
 Q52V44_9ACTO
(Q52V44)		 
[query] 557 - 4671 (10827)
[subject] 29 - 4225 (6751)
(25 hsp)		 0.0 3453   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
94
 E9KTB8_STRKN
(E9KTB8)		 
[query] 5138 - 10174 (10827)
[subject] 1556 - 6275 (6408)
(23 hsp)		 0.0 3409   45%
Product
Polyketide synthase
Gene
fkbA
Tcs_SK_034
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
95
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 559 - 4670 (10827)
[subject] 34 - 4209 (4928)
(21 hsp)		 0.0 3407   51%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
96
 E9KTB5_STRKN
(E9KTB5)		 
[query] 3428 - 8379 (10827)
[subject] 2452 - 7145 (7591)
(25 hsp)		 0.0 3407   46%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
97
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 5138 - 10158 (10827)
[subject] 1557 - 6264 (6418)
(25 hsp)		 0.0 3402   45%
Product
Polyketide synthase
Gene
fkbA
Tcs_11604BP_031
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
99
 A0ACH3_STRAM
(A0ACH3)		 
[query] 44 - 4672 (10827)
[subject] 473 - 5107 (5771)
(21 hsp)		 0.0 3368   48%
Product
Putative type I polyketide synthase
Gene
SAMR0467
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
100
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 6824 - 10782 (10827)
[subject] 2805 - 6769 (6855)
(23 hsp)		 0.0 3359   50%
Product
GelA
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]