| Alanine racemization(NFUNC_0063) | 
| 必須 | A | ALR (NRULE_0228) | Alanine racemase | AagaZ_020100013449 | 
|---|
| n-alkane hydroxylation(NFUNC_0008) | 
| 必須 | A | CYP153 (NRULE_0041) | Cytochrome P450 CYP153 |  | 
|---|
| B | ALKB (NRULE_0024) | Alkane 1-monooxygenase |  | 
| C | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit |  | 
| MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit |  | 
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100007854 AagaZ_020100004835 AagaZ_020100012424 | 
| MME (NRULE_0033) | Multicomponent monooxygenase effector protein |  | 
| 任意 |  | RUBA (NRULE_0039) | Rubredoxin | AagaZ_020100005825 | 
|---|
|  | RUBB (NRULE_0040) | Rubredoxin reductase |  | 
|  | MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit |  | 
|  | MMG2 (NRULE_0030) | Multicomponent monooxygenase gamma subunit |  | 
|  | MMG3 (NRULE_0031) | Multicomponent monooxygenase gamma subunit |  | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
| Aniline degradation (conversion into catechol)(NFUNC_0075) | 
| 必須 | A | ATDA1 (NRULE_0240) | Gamma-glutamylanilide synthetase |  | 
|---|
| ATDA3 (NRULE_0357) | Aniline dioxygenase large subunit |  | 
| ATDA4 (NRULE_0358) | Aniline dioxygenase small subunit |  | 
| 任意 |  | ATDA2 (NRULE_0241) | Putative gamma-glutamylanilide hydrolase |  | 
|---|
|  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100007854 AagaZ_020100012424 AagaZ_020100004835 | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
| Anthranilate biosynthesis(NFUNC_0038) | 
| 必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | AagaZ_020100007020 | 
|---|
| TRPE (NRULE_0143) | Anthranilate synthase component I |  | 
| Anthranilate degradation (via hydroxylation)(NFUNC_0018) | 
| 必須 | A | ANTA (NRULE_0044) | Anthranilate 1,2-dioxygenase large subunit |  | 
|---|
| ANTB (NRULE_0045) | Anthranilate 1,2-dioxygenase small subunit |  | 
| 任意 |  | ANTC (NRULE_0081) | Anthranilate 1,2-dioxygenase electron transfer component |  | 
|---|
|  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100004835 AagaZ_020100012424 AagaZ_020100007854 | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
| Aromatic hydrocarbon degradation (via hydroxylation by dioxygenase)(NFUNC_0016) | 
| 必須 | A | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit |  | 
|---|
| RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit |  | 
| CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase |  | 
| 任意 |  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100007854 AagaZ_020100012424 AagaZ_020100004835 | 
|---|
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
| Artificial lacto-N-biose biosynthesis(NFUNC_0026) | 
| 必須 | A | SP (NRULE_0109) | Sucrose phosphorylase |  | 
|---|
| GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | AagaZ_020100000592 | 
| GALE (NRULE_0111) | UDP-glucose 4-epimerase | AagaZ_020100000607 | 
| LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase |  | 
| Bacitracin resistance(NFUNC_0022) | 
| 必須 | A | UPPP (NRULE_0097) | Undecaprenyl-diphosphatase | AagaZ_020100013734 | 
|---|
| Benzoate degradation (via hydroxylation by dioxygenase)(NFUNC_0017) | 
| 必須 | A | BENA (NRULE_0046) | Benzoate 1,2-dioxygenase alpha subunit |  | 
|---|
| BENB (NRULE_0047) | Benzoate 1,2-dioxygenase beta subunit |  | 
| BEND (NRULE_0082) | 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase |  | 
| 任意 |  | BENC (NRULE_0055) | Benzoate 1,2-dioxygenase electron transfer component |  | 
|---|
|  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100007854 AagaZ_020100004835 AagaZ_020100012424 | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
| Biotin biosynthesis(NFUNC_0051) | 
| 必須 | A | BIOF (NRULE_0182) | 8-amino-7-oxononanoate synthase |  | 
|---|
| BIOA (NRULE_0183) | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | AagaZ_020100005635 | 
| BIOD (NRULE_0184) | ATP-dependent dethiobiotin synthetase BioD | AagaZ_020100005630 | 
| BIOB (NRULE_0185) | Biotin synthase |  | 
| Chlorocatechol degradation (beta-ketoadipate pathway)(NFUNC_0104) | 
| 必須 | A | PCAI (NRULE_0072) | 3-oxoadipate CoA-transferase subunit A |  | 
|---|
| PCAJ (NRULE_0073) | 3-oxoadipate CoA-transferase subunit B |  | 
| PCAF (NRULE_0074) | Beta-ketoadipyl-CoA thiolase |  | 
| CLCA (NRULE_0382) | Chlorocatechol 1,2-dioxygenase |  | 
| CLCD (NRULE_0383) | Dienelactone hydrolase | AagaZ_020100004530 AagaZ_020100013124 | 
| CLCE (NRULE_0384) | Maleylacetate reductase |  | 
| CLCB (NRULE_0387) | Chloromuconate cycloisomerase |  | 
| B | CATB2 (NRULE_0053) | (Chloro)muconate cycloisomerase |  | 
| PCAI (NRULE_0072) | 3-oxoadipate CoA-transferase subunit A |  | 
| PCAJ (NRULE_0073) | 3-oxoadipate CoA-transferase subunit B |  | 
| PCAF (NRULE_0074) | Beta-ketoadipyl-CoA thiolase |  | 
| CLCA (NRULE_0382) | Chlorocatechol 1,2-dioxygenase |  | 
| CLCD (NRULE_0383) | Dienelactone hydrolase | AagaZ_020100004530 AagaZ_020100013124 | 
| CLCE (NRULE_0384) | Maleylacetate reductase |  | 
| 任意 |  | CLCF (NRULE_0385) | Chloromuconolactone dehalogenase |  | 
|---|
| Dibenzothiophene degradation (via desulfurization)(NFUNC_0029) | 
| 必須 | A | DSZA (NRULE_0103) | Dibenzothiophene-5,5-dioxide monooxygenase |  | 
|---|
| DSZB (NRULE_0104) | 2'-hydroxybiphenyl-2-sulfinate desulfinase |  | 
| DSZC (NRULE_0105) | Dibenzothiophene monooxygenase |  | 
| 任意 |  | FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100005780 AagaZ_020100009873 | 
|---|
| Folate biosynthesis(NFUNC_0044) | 
| 必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | AagaZ_020100007020 | 
|---|
| DHPS (NRULE_0144) | Dihydropteroate synthase | AagaZ_020100011944 | 
| FOLM (NRULE_0146) | Dihydrofolate reductase FolM |  | 
| FOLB (NRULE_0158) | Dihydroneopterin aldolase | AagaZ_020100012579 | 
| FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | AagaZ_020100007220 | 
| FOLC (NRULE_0160) | Bifunctional protein FolC | AagaZ_020100000657 | 
| PABB (NRULE_0161) | Para-aminobenzoate synthase component I | AagaZ_020100007729 | 
| PABC (NRULE_0162) | Aminodeoxychorismate lyase |  | 
| B | GLAT (NRULE_0142) | Glutamine amidotransferase | AagaZ_020100007020 | 
| DHPS (NRULE_0144) | Dihydropteroate synthase | AagaZ_020100011944 | 
| FOLA (NRULE_0147) | Dihydrofolate reductase | AagaZ_020100001547 | 
| FOLB (NRULE_0158) | Dihydroneopterin aldolase | AagaZ_020100012579 | 
| FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | AagaZ_020100007220 | 
| FOLC (NRULE_0160) | Bifunctional protein FolC | AagaZ_020100000657 | 
| PABB (NRULE_0161) | Para-aminobenzoate synthase component I | AagaZ_020100007729 | 
| PABC (NRULE_0162) | Aminodeoxychorismate lyase |  | 
| C | GLAT (NRULE_0142) | Glutamine amidotransferase | AagaZ_020100007020 | 
| DHPS (NRULE_0144) | Dihydropteroate synthase | AagaZ_020100011944 | 
| DFR2 (NRULE_0148) | Dihydrofolate reductase type 2 |  | 
| FOLB (NRULE_0158) | Dihydroneopterin aldolase | AagaZ_020100012579 | 
| FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | AagaZ_020100007220 | 
| FOLC (NRULE_0160) | Bifunctional protein FolC | AagaZ_020100000657 | 
| PABB (NRULE_0161) | Para-aminobenzoate synthase component I | AagaZ_020100007729 | 
| PABC (NRULE_0162) | Aminodeoxychorismate lyase |  | 
| Human milk oligosaccharides metabolism(NFUNC_0083) | 
| 必須 | A | LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase |  | 
|---|
| 任意 |  | NAHK (NRULE_0256) | N-acetylhexosamine 1-kinase |  | 
|---|
|  | GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | AagaZ_020100000592 | 
|  | GALE (NRULE_0111) | UDP-glucose 4-epimerase | AagaZ_020100000607 | 
| 4-hydroxyphenylacetate degradation(NFUNC_0068) | 
| 必須 | A | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
|---|
| HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component |  | 
| HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| B | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component |  | 
| HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| C | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100005780 AagaZ_020100009873 | 
| HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| D | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100009873 AagaZ_020100005780 | 
| HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| E | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100009873 AagaZ_020100005780 | 
| HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| F | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100009873 AagaZ_020100005780 | 
| HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| G | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component |  | 
| HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| H | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component |  | 
| HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component |  | 
| HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase |  | 
| HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |  | 
| HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |  | 
| HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase |  | 
| HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase |  | 
| HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase |  | 
| Metal-binding protein(NFUNC_0105) | 
| 必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein |  | 
|---|
| B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator |  | 
| C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | AagaZ_020100015405 | 
| D | MNTR (NRULE_0327) | DtxR family transcriptional regulator MntR |  | 
| E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR |  | 
| F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR |  | 
| G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR |  | 
| H | NIKR (NRULE_0331) | Nickel-responsive transcriptional regulator NikR |  | 
| I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR |  | 
| J | SMTA (NRULE_0009) | Metallothionein |  | 
| Molybdate transport (ABC transporter)(NFUNC_0097) | 
| 必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | AagaZ_020100015405 | 
|---|
| 任意 |  | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator |  | 
|---|
|  | MODB (NRULE_0325) | Molybdate ABC transporter permease protein | AagaZ_020100015400 | 
|  | MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein |  | 
| Mycosamine biosynthesis(NFUNC_0095) | 
| 必須 | A | AMPHDII (NRULE_0342) | GDP-3-keto-6-deoxy-D-mannose C-3 aminotransferase |  | 
|---|
| GMD (NRULE_0343) | GDP-mannose 4,6-dehydratase | AagaZ_020100006010 | 
| 任意 |  | AMPHDI (NRULE_0341) | GDP-mycosamine glycosyltransferase |  | 
|---|
| Naphthalene degradation (via hydroxylation by dioxygenase)(NFUNC_0067) | 
| 必須 | A | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit |  | 
|---|
| RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit |  | 
| CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase |  | 
| EDIO (NRULE_0058) | extradiol dioxygenase |  | 
| NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase |  | 
| NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase |  | 
| NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase |  | 
| NAHG (NRULE_0190) | Salicylate hydroxylase |  | 
| B | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit |  | 
| RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit |  | 
| CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase |  | 
| EDIO (NRULE_0058) | extradiol dioxygenase |  | 
| NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase |  | 
| NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase |  | 
| NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase |  | 
| NAGG (NRULE_0191) | Salicylate 5-hydroxylase alpha subunit |  | 
| NAGH (NRULE_0192) | Salicylate 5-hydroxylase beta subunit |  | 
| 任意 |  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100007854 AagaZ_020100012424 AagaZ_020100004835 | 
|---|
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
| (R)-pantothenate biosynthesis(NFUNC_0030) | 
| 必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | AagaZ_020100013824 | 
|---|
| PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | AagaZ_020100005800 | 
| PANE (NRULE_0117) | 2-dehydropantoate 2-reductase |  | 
| PANC (NRULE_0118) | Pantothenate synthetase | AagaZ_020100013829 | 
| Phenol degradation(NFUNC_0028) | 
| 必須 | A | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit |  | 
|---|
| MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit |  | 
| MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit |  | 
| B | PHEA1 (NRULE_0083) | Aromatic ring hydroxylase |  | 
| C | PHEA2 (NRULE_0084) | Aromatic ring hydroxylase |  | 
| 任意 |  | FDR2 (NRULE_0057) | Ferredoxin reductase | AagaZ_020100002359 | 
|---|
|  | FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100012424 AagaZ_020100007854 AagaZ_020100004835 | 
|  | MME (NRULE_0033) | Multicomponent monooxygenase effector protein |  | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
|  | FADR1 (NRULE_0101) | NADH-dependent flavin reductase | AagaZ_020100005780 AagaZ_020100009873 | 
| Riboflavin biosynthesis(NFUNC_0058) | 
| 必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | AagaZ_020100007969 | 
|---|
| RIBA (NRULE_0201) | GTP cyclohydrolase-2 | AagaZ_020100007969 | 
| RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD |  | 
| RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | AagaZ_020100014074 | 
| RIBE (NRULE_0204) | Riboflavin synthase | AagaZ_020100005310 | 
| 任意 |  | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | AagaZ_020100011635 | 
|---|
| Toluene degradation (conversion into protocatechuate via p-cresol)(NFUNC_0007) | 
| 必須 | A | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit |  | 
|---|
| MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit |  | 
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | AagaZ_020100012424 AagaZ_020100004835 AagaZ_020100007854 | 
| MME (NRULE_0033) | Multicomponent monooxygenase effector protein |  | 
| PCHF (NRULE_0035) | 4-cresol dehydrogenase flavoprotein subunit |  | 
| PCHC (NRULE_0036) | 4-cresol dehydrogenase cytochrome c subunit |  | 
| PCHA (NRULE_0037) | p-hydroxybenzaldehyde dehydrogenase |  | 
| POBA (NRULE_0038) | p-hydroxybenzoate hydroxylase |  | 
| 任意 |  | MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit |  | 
|---|
|  | MMG2 (NRULE_0030) | Multicomponent monooxygenase gamma subunit |  | 
|  | MMG3 (NRULE_0031) | Multicomponent monooxygenase gamma subunit |  | 
|  | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | AagaZ_020100007804 | 
| Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) | 
| 必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase |  | 
|---|
| PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase |  | 
| SERC (NRULE_0210) | Phosphoserine aminotransferase | AagaZ_020100010178 | 
| PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | AagaZ_020100005305 | 
| PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | AagaZ_020100009226 |