遺伝子 : Trehalose-phosphate synthase (TPS)

遺伝子情報

ID	NRULE_0119
遺伝子ID	TPS
作成日	2013/01/22
タンパク質名	Protein name Full Trehalose-phosphate synthase EC EC 2.4.1.- Synonym Full Trehalose-6-phosphate synthase
遺伝子名	otsA
遺伝子条件	TIGRFAMs; TIGR02400; hit=1 OR BLASTP; O06353; hit=1; score=1000; pid=50
参照	Gene Ontology GO GO:0005618, C:cell wall, IDA:MTBBASE GO:0005829, C:cytosol, TAS:Reactome GO:0005886, C:plasma membrane, IDA:MTBBASE GO:0047260, F:alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity, IDA:MTBBASE GO:0003825, F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, IDA:MTBBASE GO:0030145, F:manganese ion binding, IDA:MTBBASE GO:0040007, P:growth, IMP:MTBBASE GO:0051289, P:protein homotetramerization, IPI:MTBBASE GO:0005992, P:trehalose biosynthetic process, IDA:MTBBASE Phylogenomic databases eggNOG COG0380, - HOGENOM HOG000191477, - KO K00697, - ProtClustDB CLSK872185, - Enzyme and pathway databases UniPathway UPA00299, - Family and domain databases InterPro IPR001830, Glyco_trans_20 Pfam PF00982, Glyco_transf_20, 1
配列の特徴	該当データなし
注釈	Function Catalyzes the transfer of glucose from a nucleoside diphosphate-glucose to glucose-6-phosphate to form trehalose-6- phosphate and nucleoside diphosphate. TPS is specific for the glucosyl acceptor but not for the glucosyl donor Catalytic activity Nucleoside diphosphate-glucose + D-glucose 6- phosphate = trehalose 6-phosphate + nucleoside diphosphate Pathway Glycan biosynthesis; trehalose biosynthesis Subunit structure Homotetramer Sequence similarities Belongs to the glycosyltransferase 20 family
参考文献	O06353 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). 12473104 Trehalose-phosphate synthase of Mycobacterium tuberculosis. Cloning, expression and properties of the recombinant enzyme. (Eur J Biochem. 2002) P31677 Escherichia coli (strain K12). 3131312 Biochemical and genetic characterization of osmoregulatory trehalose synthesis in Escherichia coli. (J Bacteriol. 1988)

関与する機能

機能名
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acaricomes phytoseiuli	107788	C501_00405	trehalose-phosphate synthase
Actinoalloteichus cyanogriseus	14455	G443_01_06900	alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Actinoalloteichus spitiensis	102582	ACTIDRAF_13575	trehalose-phosphate synthase
Actinoplanes missouriensis	102363	AMIS_10890	putative trehalose-6-phosphate synthase
Actinopolyspora iraqiensis	103187	ACTIR_430_00020	alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Actinosynnema mirum	14064	Amir_0371	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Amycolatopsis azurea	14573	C791_1271	Alpha,alpha-trehalose-phosphate synthase
		C791_7147	Alpha,alpha-trehalose-phosphate synthase
Amycolatopsis mediterranei	13415	RAM_44490	trehalose-6-phosphate synthase
Archaeoglobus profundus	100127	Arcpr_1593	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Arthrobacter globiformis	12137	ARGLB_012_00090	alpha,alpha-trehalose-phosphate synthase
Austwickia chelonae	105200	AUCHE_08_00860	alpha,alpha-trehalose-phosphate synthase
Azorhizobium caulinodans	14845	AZC_0482	OtsA trehalose-6-phosphate synthase
Beutenbergia cavernae	16432	Bcav_0796	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Brevibacterium linens	12170	BlinB_010200014950	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Catenulispora acidiphila	102108	Caci_2546	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
		Caci_2644	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
		Caci_3724	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Caulobacter segnis	15250	Cseg_1575	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Cellulomonas fimi	15513	Celf_0618	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Cellulomonas flavigena	3775	Cfla_0676	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Cellulophaga lytica	14961	Celly_2540	trehalose-phosphatase
Corynebacterium ammoniagenes	12612	HMPREF0281_01450	putative alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Corynebacterium callunae	15359	H924_11075	alpha,alpha-trehalose-phosphate synthase
Corynebacterium efficiens	100395	CE2508	putative trehalose-6-phosphate synthase
Corynebacterium glutamicum	12168	Cgl2624	Trehalose-6-phosphate synthase
Corynebacterium glutamicum	12153	KIQ_12590	alpha,alpha-trehalose-phosphate synthase
Corynebacterium matruchotii	15360	HMPREF0299_7568	putative alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Corynebacterium striatum	15291	HMPREF0308_2618	putative alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Corynebacterium terpenotabidum	14764	A606_02185	alpha,alpha-trehalose-phosphate synthase
Cupriavidus metallidurans	102507	Rmet_0357	trehalose-6-phosphate synthase
Enterobacter aerogenes	13534	EAE_22940	trehalose-6-phosphate synthase
Enterobacter cloacae subsp. cloacae	13535	ECL_01398	trehalose-6-phosphate synthase
Enterobacter hormaechei	105718	HMPREF9086_2897	alpha,alpha-trehalose-phosphate synthase
Escherichia coli	3972	EcolC_1738	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Escherichia coli	13500	WFL_10160	trehalose-6-phosphate synthase
Escherichia coli	12713	Y75_1893	trehalose-6-phosphate synthase
Escherichia fergusonii	102419	EFER_1127	trehalose-6-phosphate synthase
Escherichia hermannii	105704	EH105704_01_03970	alpha,alpha-trehalose-phosphate synthase
Geodermatophilus obscurus	13315	Gobs_5012	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Gordonia aichiensis	108223	GOACH_04_03210	alpha,alpha-trehalose-phosphate synthase
Gordonia alkanivorans	16433	GOALK_050_00720	alpha,alpha-trehalose-phosphate synthase
Gordonia amarae	15530	GOAMR_26_00160	alpha,alpha-trehalose-phosphate synthase
Gordonia amicalis	100051	GOAMI_14_01950	alpha,alpha-trehalose-phosphate synthase
Gordonia araii	100433	GOARA_082_00320	alpha,alpha-trehalose-phosphate synthase
Gordonia bronchialis	16047	Gbro_0808	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Gordonia effusa	100432	GOEFS_035_00070	alpha,alpha-trehalose-phosphate synthase
Gordonia hirsuta	16056	GOHSU_14_00880	alpha,alpha-trehalose-phosphate synthase
Gordonia namibiensis	108229	GONAM_22_00270	alpha,alpha-trehalose-phosphate synthase
Gordonia otitidis	100426	GOOTI_130_00600	alpha,alpha-trehalose-phosphate synthase
Gordonia polyisoprenivorans	16320	GOPIP_087_02380	alpha,alpha-trehalose-phosphate synthase
Gordonia rhizosphera	16068	GORHZ_046_00700	alpha,alpha-trehalose-phosphate synthase
Gordonia rubripertincta	101908	GORBP_100_00140	alpha,alpha-trehalose-phosphate synthase
Gordonia sihwensis	108236	GSI01S_25_00850	alpha,alpha-trehalose-phosphate synthase
Gordonia soli	108243	GS4_32_01300	alpha,alpha-trehalose-phosphate synthase
Gordonia sputi	100414	GOSPT_142_00060	alpha,alpha-trehalose-phosphate synthase
Gordonia terrae	100016	GOTRE_136_00600	alpha,alpha-trehalose-phosphate synthase
Intrasporangium calvum	12989	Intca_2909	trehalose 6-phosphate synthase
Jonesia denitrificans	15587	Jden_2063	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Kineococcus radiotolerans	101839	Krad_0920	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Kineosphaera limosa	100340	KILIM_027_00020	alpha,alpha-trehalose-phosphate synthase
Klebsiella pneumoniae	14438	KPR_3305
Klebsiella pneumoniae subsp. rhinoscleromatis	105682	HMPREF0484_2194	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Kocuria rhizophila	103217	KRH_18540	alpha,alpha-trehalose-phosphate synthase
Kribbella flavida	14399	Kfla_1215	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Kytococcus sedentarius	15357	Ksed_03840	trehalose 6-phosphate synthase
Microlunatus phosphovorus	101784	MLP_33530	alpha,alpha-trehalose-phosphate synthase
Micromonospora aurantiaca	16155	Micau_4541	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
		Micau_4956	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Microscilla marina	16560	M23134_00593	trehalose-6-phosphate synthase-phosphatase
Mobilicoccus pelagius	104925	MOPEL_005_00420	alpha,alpha-trehalose-phosphate synthase
Nakamurella multipartita	105858	Namu_4915	trehalose-phosphatase
Ochrobactrum anthropi	15819	Oant_2713	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Ochrobactrum intermedium	15820	OINT_1000603	alpha,alpha-trehalose-phosphate synthase [UDP-forming]
Propionibacterium acidipropionici	12425	PACID_18560	Alpha,alpha-trehalose-phosphate synthase
Propionibacterium avidum	15671	HMPREF9153_2002	alpha,alpha-trehalose-phosphate synthase
Pseudomonas stutzeri	14165	PSTAB_3283	alpha,alpha-trehalose-phosphate synthase
Rahnella aquatilis	105701	Rahaq2_4935	UDP-forming alpha,alpha-trehalose-phosphate synthase
Renibacterium salmoninarum	15589	RSal33209_0446	trehalose-6-phosphate synthase
Rhizobium etli	15573	RHE_CH00476	trehalose-6-phosphate synthase protein
Rhizobium sp.	101917	NGR_a02090	putative alpha,alpha-trehalose-6-phosphate synthase OtsA
Rhizobium tropici	15247	RTCIAT899_CH02085	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Rhodobacter sphaeroides	12203	RSP_0948	probable OtsA trehalose-6-phosphate synthase
Rhodococcus erythropolis	100887	RER_09680	alpha,alpha-trehalose-phosphate synthase
		RER_12840	alpha,alpha-trehalose-phosphate synthase
Rhodococcus opacus	108011	ROP_02140	putative alpha,alpha-trehalose-phosphate synthase
		ROP_48060	putative alpha,alpha-trehalose-phosphate synthase
Saccharomonospora azurea	14651	SacazDRAFT_02276	Trehalose-6-phosphate synthase
Saccharomonospora cyanea	14841	SaccyDRAFT_4624	Trehalose-6-phosphate synthase
Saccharomonospora glauca	14831	SacglDRAFT_03893	Trehalose-6-phosphate synthase
Saccharomonospora viridis	12207	Svir_35050	trehalose 6-phosphate synthase
Saccharopolyspora erythraea	13426	SACE_0462	trehalose-6-phosphate synthase
Saccharopolyspora spinosa	15153	SspiN1_010100021438	trehalose-phosphate synthase
Saccharothrix espanaensis	15066	BN6_04110	alpha,alpha-trehalose-phosphate synthase
Salinispora arenicola	105043	Q5S_2331_00060	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
		Q5S_2542_00040	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Salinispora tropica	105044	Strop_3271	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
		Strop_3543	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Sanguibacter keddieii	16158	Sked_31700	trehalose 6-phosphate synthase
Shimwellia blattae	105725	EB105725_04_03540	alpha,alpha-trehalose-phosphate synthase
Solitalea canadensis	15130	Solca_2056	UDP-forming alpha,alpha-trehalose-phosphate synthase
Sphingobacterium spiritivorum	14948	HMPREF0766_13135	trehalose-phosphatase
Sphingobium japonicum	101211	SJA_C1-14720	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Stackebrandtia nassauensis	102104	Snas_4642	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Streptosporangium roseum	3776	Sros_6769	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Thermobispora bispora	14880	Tbis_2294	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Thermomonospora curvata	15933	Tcur_1967	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Thermoproteus neutrophilus	100436	Tneu_0273	alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Tsukamurella paurometabola	16120	Tpau_3642	Alpha,alpha-trehalose-phosphate synthase (UDP- forming)
Xylanimonas cellulosilytica	107835	Xcel_2949	trehalose-phosphatase