BLAST table : Grana_00280

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
ACPX_STRVN
(P12885)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
2e-38 162   100% Granaticin polyketide synthase acyl carrier protein gra-orf3 Streptomyces violaceoruber
2
E3T4B2_9ACTO
(E3T4B2)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
2e-29 132   80% Acyl carrier protein gra-orf3 Streptomyces vietnamensis
3
D3U1U9_9BACT
(D3U1U9)
[query] 4 - 85 (85)
[subject] 7 - 88 (89)
6e-24 114   71% Acyl carrier protein uncultured soil bacterium V167
4
Q9X463_STRAE
(Q9X463)
Jump to Naphcy_00030
[query] 1 - 80 (85)
[subject] 1 - 80 (86)
4e-22 108   71% Acyl carrier protein ncnC Streptomyces arenae
5
Q9FCM6_STRAT
(Q9FCM6)
[query] 1 - 85 (85)
[subject] 1 - 85 (86)
9e-22 107   66% Putative Acyl carrier protein Streptomyces antibioticus
6
D9W8G0_9ACTO
(D9W8G0)
[query] 1 - 85 (85)
[subject] 1 - 85 (86)
2e-19 99.4 62% Granaticin polyketide synthase acyl carrier protein (ACP) SSOG_02380 Streptomyces himastatinicus ATCC 53653
7
Q54283_SACHI
(Q54283)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
7e-19 97.4 59% Acyl carrier protein Saccharopolyspora hirsuta
8
D6EWA5_STRLI
(D6EWA5)
[query] 4 - 85 (85)
[subject] 5 - 86 (86)
4e-18 94.7 62% Acyl carrier protein SSPG_02600 Streptomyces lividans TK24
9
ACPX_STRCO
(Q02054)
Jump to Actino_00200
[query] 4 - 85 (85)
[subject] 5 - 86 (86)
4e-18 94.7 62% Actinorhodin polyketide synthase acyl carrier protein
actI ORF3
SCO5089
SCBAC28G1.15
Streptomyces coelicolor
10
Q9F6C8_9ACTO
(Q9F6C8)
Jump to R1128_00140
[query] 4 - 74 (85)
[subject] 1 - 71 (82)
1e-16 90.1 63% Acyl carrier protein zhuN Streptomyces sp. R1128
11
D2XDY1_9PSEU
(D2XDY1)
[query] 3 - 79 (85)
[subject] 4 - 80 (86)
1e-16 90.1 55% AzicC azicC Kibdelosporangium sp. MJ126-NF4
12
D7BZR1_STRBB
(D7BZR1)
[query] 1 - 84 (85)
[subject] 4 - 87 (94)
1e-16 89.7 55% Phosphopantetheine-binding protein SBI_06846 Streptomyces bingchenggensis (strain BCW-1)
13
D9UBR7_STRPR
(D9UBR7)
[query] 4 - 77 (85)
[subject] 1 - 74 (84)
3e-16 88.6 64% Putative acyl carrier protein cpp17 Streptomyces pristinaespiralis
14
B5HIU9_STRPR
(B5HIU9)
[query] 4 - 77 (85)
[subject] 1 - 74 (84)
3e-16 88.6 64% Acyl carrier protein SSDG_05086 Streptomyces pristinaespiralis ATCC 25486
15
E8W950_STRFA
(E8W950)
[query] 1 - 81 (85)
[subject] 1 - 81 (81)
2e-15 85.9 56% Phosphopantetheine-binding protein Sfla_5316 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
16
Q84CJ5_9ACTO
(Q84CJ5)
[query] 4 - 85 (85)
[subject] 27 - 107 (110)
4e-15 84.7 56% Putative acyl carrier protein kinC Streptomyces murayamaensis
17
Q4R0M0_STRCX
(Q4R0M0)
Jump to Chart_00120
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
5e-15 84.3 53% ChaC protein chaC Streptomyces chartreusis
18
D3CXU1_9ACTO
(D3CXU1)
[query] 1 - 81 (85)
[subject] 1 - 81 (94)
7e-15 84.3 59% Phosphopantetheine-binding protein FrEUN1fDRAFT_2361 Frankia sp. EUN1f
19
Q84CI0_9ACTO
(Q84CI0)
[query] 4 - 85 (85)
[subject] 6 - 87 (90)
9e-15 83.6 51% Putative acyl carrier protein pd2C Streptomyces sp. WP 4669
20
Q93LY2_9ACTO
(Q93LY2)
[query] 4 - 83 (85)
[subject] 6 - 85 (89)
2e-14 82.8 53% Acyl carrier protein PgaC pgaC Streptomyces sp. PGA64
21
C4NYK1_9ACTO
(C4NYK1)
[query] 4 - 79 (85)
[subject] 5 - 80 (90)
2e-14 82.8 57% SaqC saqC Micromonospora sp. Tu 6368
22
Q0MRN3_9ACTO
(Q0MRN3)
[query] 1 - 85 (85)
[subject] 1 - 85 (87)
2e-14 82.8 52% Putative acyl carrier protein Streptomyces toxytricini
23
F4FBT5_VERMA
(F4FBT5)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
7e-14 80.9 52% Putative uncharacterized protein VAB18032_18165 Verrucosispora maris (strain AB-18-032)
24
Q9AMJ1_STRAT
(Q9AMJ1)
[query] 4 - 78 (85)
[subject] 6 - 80 (88)
9e-14 80.5 55% Putative acyl carrier protein SimA3
Sim4
simA3
sim4
Streptomyces antibioticus
25
D1XRF1_9ACTO
(D1XRF1)
[query] 4 - 78 (85)
[subject] 7 - 81 (92)
1e-13 80.1 55% Phosphopantetheine-binding protein SACTEDRAFT_5261 Streptomyces sp. SA3_actE
26
Q54219_STRGR
(Q54219)
Jump to Griseu_00030
[query] 4 - 80 (85)
[subject] 6 - 82 (89)
2e-13 79.3 55% Acyl carrier protein Streptomyces griseus
27
F2RC17_STRVP
(F2RC17)
[query] 4 - 79 (85)
[subject] 6 - 81 (89)
2e-13 79   55% Acyl carrier protein SVEN_5982 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
28
Q56165_9ACTO
(Q56165)
Jump to Jado_00100
[query] 4 - 79 (85)
[subject] 6 - 81 (89)
2e-13 79   55% Acyl carrier protein acp Streptomyces venezuelae
29
B5HT06_9ACTO
(B5HT06)
[query] 3 - 84 (85)
[subject] 5 - 91 (91)
2e-13 79   51% Phosphopantetheine-binding protein SSEG_02723 Streptomyces sviceus ATCC 29083
30
Q7WT30_9ACTO
(Q7WT30)
Jump to Medem_00120
[query] 6 - 78 (85)
[subject] 10 - 82 (91)
3e-13 79   55% Acyl carrier protein (ACP) med-ORF23 Streptomyces sp. AM-7161
31
D5MRI6_9ACTO
(D5MRI6)
[query] 4 - 79 (85)
[subject] 6 - 81 (87)
3e-13 78.6 55% Putative acyl carrier protein hrbM Streptomyces sp. 2238-SVT4
32
D6MSY3_9ACTO
(D6MSY3)
[query] 1 - 78 (85)
[subject] 1 - 78 (85)
3e-13 78.6 51% SsfC ssfC Streptomyces sp. SF2575
33
E3J3P9_FRASU
(E3J3P9)
[query] 1 - 79 (85)
[subject] 1 - 79 (84)
3e-13 78.6 48% Phosphopantetheine-binding protein FraEuI1c_1319 Frankia sp. (strain EuI1c)
34
Q2HR22_9ACTO
(Q2HR22)
Jump to Sch475_00360
[query] 4 - 78 (85)
[subject] 6 - 80 (89)
3e-13 78.6 55% Putative acyl carrier protein schP6 Streptomyces sp. SCC 2136
35
D9W584_9ACTO
(D9W584)
[query] 4 - 78 (85)
[subject] 6 - 80 (89)
6e-13 77.8 53% Aur1F SSNG_07314 Streptomyces sp. C
36
Q54175_STRFR
(Q54175)
Jump to Urd_00140
[query] 4 - 78 (85)
[subject] 6 - 80 (89)
1e-12 76.6 52% Putative acyl carrier protein UrdC Streptomyces fradiae
Streptomyces roseoflavus
37
D2AY46_STRRD
(D2AY46)
[query] 4 - 78 (85)
[subject] 7 - 81 (86)
1e-12 76.6 53% Putative uncharacterized protein Sros_4152 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
38
Q56HA0_STRAU
(Q56HA0)
[query] 2 - 78 (85)
[subject] 9 - 85 (94)
2e-12 76.3 52% Aur1F aur1F Streptomyces aureofaciens
39
D1H0K3_9ACTO
(D1H0K3)
[query] 4 - 80 (85)
[subject] 6 - 82 (82)
2e-12 76.3 53% Putative acyl carrier protein ravC1 Streptomyces sp. C23201NS3
40
Q47QL1_THEFY
(Q47QL1)
[query] 4 - 84 (85)
[subject] 6 - 86 (86)
2e-12 76.3 53% Actinorhodin polyketide synthase acyl carrier protein / 3-oxoacyl-ACP synthase acyl carrier protein Tfu_1220 Thermobifida fusca (strain YX)
41
D9UBS9_STRPR
(D9UBS9)
[query] 1 - 80 (85)
[subject] 1 - 80 (87)
2e-12 76.3 51% Putative acyl carrier protein cpp5 Streptomyces pristinaespiralis
42
E5RLL9_9ACTO
(E5RLL9)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
2e-12 76.3 51% Putative acyl carrier protein pnxC Streptomyces sp. TA-0256
43
Q2J5E7_FRASC
(Q2J5E7)
[query] 4 - 76 (85)
[subject] 6 - 78 (98)
2e-12 75.9 55% Phosphopantetheine-binding Francci3_4147 Frankia sp. (strain CcI3)
44
C7PWQ7_CATAD
(C7PWQ7)
[query] 4 - 79 (85)
[subject] 6 - 81 (102)
2e-12 75.5 53% Phosphopantetheine-binding Caci_6487 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
45
E2D2I6_9BACT
(E2D2I6)
[query] 4 - 78 (85)
[subject] 1 - 72 (145)
3e-12 75.5 52% Acyl carrier protein uncultured soil bacterium
46
Q9ZGD5_STRCY
(Q9ZGD5)
Jump to Lando_00050
[query] 1 - 78 (85)
[subject] 3 - 80 (89)
3e-12 75.5 53% Acyl carrier protein homolog lanC Streptomyces cyanogenus
47
Q9FD17_STRCU
(Q9FD17)
[query] 1 - 84 (85)
[subject] 1 - 85 (87)
4e-12 75.1 48% Acyl carrier protein rubC Streptomyces collinus
48
A1C177_9ACTO
(A1C177)
Jump to Aran_00090
[query] 1 - 85 (85)
[subject] 1 - 85 (88)
4e-12 74.7 46% Acyl carrier protein Streptomyces echinatus
49
Q9XDZ8_9ACTO
(Q9XDZ8)
[query] 1 - 78 (85)
[subject] 1 - 78 (88)
6e-12 74.3 49% Polyketide synthase Actinomadura verrucosospora
50
Q70J95_STRGR
(Q70J95)
Jump to Chro_00030
[query] 4 - 78 (85)
[subject] 2 - 76 (83)
6e-12 74.3 51% Acyl carrier protein cmmS Streptomyces griseus subsp. griseus
51
B6SEF3_9ACTO
(B6SEF3)
Jump to Alnu_00080
[query] 4 - 85 (85)
[subject] 3 - 84 (84)
7e-12 73.9 49% AlnN acyl carrier protein alnN Streptomyces sp. CM020
52
Q54996_9ACTO
(Q54996)
Jump to Fren_00140
[query] 1 - 84 (85)
[subject] 1 - 83 (83)
9e-12 73.9 50% Acyl carrier protein frnN Streptomyces roseofulvus
53
Q6VMI9_STRAM
(Q6VMI9)
[query] 4 - 85 (85)
[subject] 6 - 89 (89)
1e-11 73.6 50% Putative acyl carrier protein alpC
DSMT0183
Streptomyces ambofaciens
54
Q1RQS2_STRAM
(Q1RQS2)
[query] 4 - 85 (85)
[subject] 6 - 89 (89)
1e-11 73.6 50% Putative acyl carrier protein alpC
SAMT0163
SAMT0164
Streptomyces ambofaciens ATCC 23877
55
A8KQY0_9ACTO
(A8KQY0)
Jump to Ello_00130
[query] 4 - 78 (85)
[subject] 2 - 76 (83)
1e-11 73.2 48% Acyl carrier protein elmM Streptomyces olivaceus
56
F6K0W3_9BACT
(F6K0W3)
[query] 1 - 79 (85)
[subject] 3 - 81 (91)
2e-11 73.2 48% Acyl carrier protein uncultured bacterium BAC AB649/1850
57
Q48377_KIBAR
(Q48377)
[query] 4 - 83 (85)
[subject] 3 - 82 (82)
2e-11 72.8 48% ArdIorf3 ardIorf3 Kibdelosporangium aridum
58
Q6ZZW0_STRAT
(Q6ZZW0)
Jump to Ovied_00130
[query] 4 - 78 (85)
[subject] 6 - 81 (90)
2e-11 72.8 51% Acyl carrier protein ovmS Streptomyces antibioticus
59
D1A6T5_THECD
(D1A6T5)
[query] 1 - 78 (85)
[subject] 1 - 77 (82)
2e-11 72.8 54% Phosphopantetheine-binding protein Tcur_2794 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
60
D1H098_9ACTO
(D1H098)
[query] 1 - 80 (85)
[subject] 3 - 82 (83)
2e-11 72.8 50% Putative acyl carrier protein chryC1 Streptomyces albaduncus
61
Q67G32_9ACTO
(Q67G32)
Jump to Heda_00260
[query] 1 - 85 (85)
[subject] 235 - 319 (319)
2e-11 72.4 48% Putative bifunctional cyclase dehydratase and ACP fusion Streptomyces griseoruber
62
Q8VWB1_9ACTO
(Q8VWB1)
[query] 1 - 85 (85)
[subject] 1 - 84 (91)
3e-11 72   47% AknD aknD Streptomyces galilaeus
63
D2SZ01_MICEC
(D2SZ01)
[query] 4 - 85 (85)
[subject] 1 - 82 (82)
3e-11 72   48% Acyl carrier protein Micromonospora echinospora subsp. challisensis
64
Q3S8R2_STRRM
(Q3S8R2)
Jump to Oxtet_00040
[query] 16 - 78 (85)
[subject] 16 - 78 (95)
5e-11 71.2 49% OxyC oxyC Streptomyces rimosus
65
ACPX_STRRM
(P43677)
[query] 16 - 78 (85)
[subject] 16 - 78 (95)
5e-11 71.2 49% Oxytetracycline polyketide synthase acyl carrier protein Streptomyces rimosus
66
Q9FAR3_STRAU
(Q9FAR3)
[query] 1 - 78 (85)
[subject] 1 - 77 (84)
9e-11 70.5 53% Acyl carrier protein tcsF Streptomyces aureofaciens
67
C7QAF4_CATAD
(C7QAF4)
[query] 1 - 80 (85)
[subject] 6 - 85 (92)
1e-10 70.1 49% Phosphopantetheine-binding Caci_3548 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
68
Q9L549_9ACTO
(Q9L549)
Jump to Acla_00090
[query] 1 - 85 (85)
[subject] 1 - 84 (91)
2e-10 69.3 46% AknD aknD Streptomyces galilaeus
69
ACPX_STRGA
(P12884)
[query] 1 - 82 (85)
[subject] 1 - 79 (83)
3e-10 68.9 47% Tetracenomycin C polyketide synthase acyl carrier protein tcmM Streptomyces glaucescens
70
Q93H99_STRAW
(Q93H99)
[query] 1 - 78 (85)
[subject] 1 - 79 (86)
4e-10 68.2 47% Acyl carrier protein
Putative acyl carrier protein
pks9-1
SAV2373
SAV_2373
Streptomyces avermitilis
71
A4X726_SALTO
(A4X726)
[query] 1 - 78 (85)
[subject] 1 - 78 (84)
4e-10 68.2 45% Phosphopantetheine-binding Strop_2225 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
72
Q2PA09_9ACTO
(Q2PA09)
Jump to Stref_00060
[query] 16 - 83 (85)
[subject] 16 - 84 (86)
5e-10 68.2 57% Acyl carrier protein stfS Streptomyces steffisburgensis
73
D3U9Z5_9ACTO
(D3U9Z5)
[query] 1 - 84 (85)
[subject] 51 - 134 (134)
6e-10 67.8 46% Acyl carrier protein sfaO Streptomyces flaveolus
74
A7DWI7_STRTE
(A7DWI7)
[query] 1 - 84 (85)
[subject] 1 - 84 (86)
1e-09 66.2 46% Putative acyl carrier protein (ACP) llpD Streptomyces tendae
75
D1H0A3_9ACTO
(D1H0A3)
[query] 2 - 78 (85)
[subject] 3 - 77 (87)
2e-09 65.9 48% Putative acyl carrier protein chryC Streptomyces albaduncus
76
B5G884_9ACTO
(B5G884)
[query] 1 - 79 (85)
[subject] 1 - 79 (92)
3e-09 65.5 43% Oxytetracycline polyketide synthase acyl carrier protein (ACP) SSBG_00492 Streptomyces sp. SPB74
77
C0JWB6_9ACTO
(C0JWB6)
Jump to Polk_00210
[query] 1 - 78 (85)
[subject] 1 - 78 (85)
3e-09 65.1 46% PokP3 pokP3 Streptomyces diastatochromogenes
78
Q2J5J5_FRASC
(Q2J5J5)
[query] 1 - 81 (85)
[subject] 1 - 81 (87)
4e-09 65.1 46% Phosphopantetheine-binding Francci3_4099 Frankia sp. (strain CcI3)
79
Q2MGC9_STRGR
(Q2MGC9)
Jump to Fred_00100
[query] 1 - 82 (85)
[subject] 1 - 82 (84)
5e-09 64.3 40% ACP Streptomyces griseus
80
B0LJ41_9ACTO
(B0LJ41)
[query] 1 - 79 (85)
[subject] 1 - 79 (93)
8e-09 63.9 42% Lcz24 lcz24 Streptomyces sanglieri
81
ACPX_STRCM
(P41174)
[query] 4 - 78 (85)
[subject] 6 - 79 (88)
9e-09 63.5 51% Monensin polyketide synthase acyl carrier protein Streptomyces cinnamonensis
82
D1XHA1_9ACTO
(D1XHA1)
[query] 1 - 78 (85)
[subject] 1 - 79 (86)
1e-08 63.2 44% Phosphopantetheine-binding protein SACTEDRAFT_2152 Streptomyces sp. SA3_actE
83
E2EKK1_9ACTO
(E2EKK1)
[query] 2 - 80 (85)
[subject] 3 - 81 (85)
1e-08 63.2 42% Acyl carrier protein sanH Streptomyces sp. SANK 61196
84
Q54497_STRNO
(Q54497)
Jump to Nogl_00390
[query] 3 - 85 (85)
[subject] 4 - 86 (86)
2e-08 62.8 47% Snoa3 snoa3 Streptomyces nogalater
85
D1H0J8_9ACTO
(D1H0J8)
[query] 1 - 78 (85)
[subject] 1 - 76 (86)
3e-08 62.4 46% Putative acyl carrier protein ravC Streptomyces sp. C23201NS3
86
D7RFJ7_AMYOR
(D7RFJ7)
[query] 4 - 78 (85)
[subject] 6 - 78 (86)
3e-08 62   48% Putative acyl carrier protein bexC Amycolatopsis orientalis subsp. vinearia
87
Q7X2H6_9ACTO
(Q7X2H6)
Jump to Gilvo_00200
[query] 2 - 85 (85)
[subject] 3 - 86 (89)
3e-08 62   45% Putative acyl carrier protein gilC Streptomyces griseoflavus
88
D8I4L9_AMYMU
(D8I4L9)
[query] 4 - 80 (85)
[subject] 2 - 77 (81)
8e-08 60.8 44% 3-oxoacyl-ACP synthase acylcarrier protein actI
AMED_5433
Amycolatopsis mediterranei (strain U-32)
89
Q9F6D5_9ACTO
(Q9F6D5)
Jump to R1128_00070
[query] 1 - 85 (85)
[subject] 1 - 85 (86)
9e-08 60.5 44% Acyl carrier protein zhuG Streptomyces sp. R1128
90
E8SDG6_MICSL
(E8SDG6)
[query] 3 - 78 (85)
[subject] 6 - 82 (89)
1e-07 60.1 44% Phosphopantetheine-binding protein ML5_4404 Micromonospora sp. (strain L5)
91
D9W574_9ACTO
(D9W574)
[query] 2 - 78 (85)
[subject] 5 - 81 (90)
2e-07 59.7 43% Putative uncharacterized protein SSNG_07304 Streptomyces sp. C
92
D9T2B4_MICAI
(D9T2B4)
[query] 3 - 78 (85)
[subject] 6 - 82 (89)
2e-07 59.7 44% Phosphopantetheine-binding Micau_4017 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
93
B0LJ07_9ACTO
(B0LJ07)
[query] 1 - 78 (85)
[subject] 1 - 78 (92)
2e-07 59.3 44% Lct24 lct24 Streptomyces rishiriensis
94
Q9ZAU0_STRPE
(Q9ZAU0)
Jump to Adria_00040
[query] 1 - 78 (85)
[subject] 1 - 77 (84)
4e-07 58.5 45% Daunorubicin acyl carrier protein dpsG Streptomyces peucetius
95
C7N0D3_SACVD
(C7N0D3)
[query] 1 - 84 (85)
[subject] 1 - 84 (89)
4e-07 58.2 37% Acyl carrier protein Svir_33710 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
96
Q53878_STRS5
(Q53878)
Jump to Dauno_00020
[query] 1 - 78 (85)
[subject] 1 - 77 (84)
5e-07 57.8 45% Acyl carrier protein dauA(g) Streptomyces sp. (strain C5)
97
Q53673_STRAA
(Q53673)
Jump to Mith_00160
[query] 4 - 83 (85)
[subject] 1 - 80 (85)
6e-07 57.8 41% Acyl carrier protein mtmS Streptomyces argillaceus
98
E1ARN2_STRAU
(E1ARN2)
[query] 1 - 78 (85)
[subject] 1 - 78 (89)
1e-06 56.2 48% Putative acyl carrier protein sa22 Streptomyces aureofaciens
99
O32453_9ACTO
(O32453)
[query] 5 - 79 (85)
[subject] 7 - 81 (87)
2e-06 55.8 53% ORF 3
PdmC
pdmC Actinomadura hibisca
100
Q8KSY8_9ACTO
(Q8KSY8)
Jump to Griseo_00040
[query] 13 - 78 (85)
[subject] 12 - 77 (86)
3e-06 55.5 45% Putative acyl carrier protein GrhC grhC Streptomyces sp. JP95
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
ACPX_STRVN
(P12885)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
2e-38 162   100%
Product
Granaticin polyketide synthase acyl carrier protein
Gene
gra-orf3
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
3uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
[pubmed all]
4
Q9X463_STRAE
(Q9X463)
Jump to Naphcy_00030
[query] 1 - 80 (85)
[subject] 1 - 80 (86)
4e-22 108   71%
Product
Acyl carrier protein
Gene
ncnC
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]
5
Q9FCM6_STRAT
(Q9FCM6)
[query] 1 - 85 (85)
[subject] 1 - 85 (86)
9e-22 107   66%
Product
Putative Acyl carrier protein
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11700358 [Medline] 21557167
A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001]
7
Q54283_SACHI
(Q54283)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
7e-19 97.4 59%
Product
Acyl carrier protein
Gene
 
Organism
Saccharopolyspora hirsuta
1uniprot[Pubmed] 8341260 [Medline] 93341453
Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993]
9
ACPX_STRCO
(Q02054)
Jump to Actino_00200
[query] 4 - 85 (85)
[subject] 5 - 86 (86)
4e-18 94.7 62%
Product
Actinorhodin polyketide synthase acyl carrier protein
actI ORF3
Gene
SCO5089
SCBAC28G1.15
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1527048 [Medline] 92406871
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
3uniprot[Pubmed] 9166770 [Medline] 97309355
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).(Biochemistry) [1997]
[pubmed all]
10
Q9F6C8_9ACTO
(Q9F6C8)
Jump to R1128_00140
[query] 4 - 74 (85)
[subject] 1 - 71 (82)
1e-16 90.1 63%
Product
Acyl carrier protein
Gene
zhuN
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
11
D2XDY1_9PSEU
(D2XDY1)
[query] 3 - 79 (85)
[subject] 4 - 80 (86)
1e-16 90.1 55%
Product
AzicC
Gene
azicC
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
12
D7BZR1_STRBB
(D7BZR1)
[query] 1 - 84 (85)
[subject] 4 - 87 (94)
1e-16 89.7 55%
Product
Phosphopantetheine-binding protein
Gene
SBI_06846
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
13
D9UBR7_STRPR
(D9UBR7)
[query] 4 - 77 (85)
[subject] 1 - 74 (84)
3e-16 88.6 64%
Product
Putative acyl carrier protein
Gene
cpp17
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
17
Q4R0M0_STRCX
(Q4R0M0)
Jump to Chart_00120
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
5e-15 84.3 53%
Product
ChaC protein
Gene
chaC
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
20
Q93LY2_9ACTO
(Q93LY2)
[query] 4 - 83 (85)
[subject] 6 - 85 (89)
2e-14 82.8 53%
Product
Acyl carrier protein PgaC
Gene
pgaC
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
21
C4NYK1_9ACTO
(C4NYK1)
[query] 4 - 79 (85)
[subject] 5 - 80 (90)
2e-14 82.8 57%
Product
SaqC
Gene
saqC
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
22
Q0MRN3_9ACTO
(Q0MRN3)
[query] 1 - 85 (85)
[subject] 1 - 85 (87)
2e-14 82.8 52%
Product
Putative acyl carrier protein
Gene
 
Organism
Streptomyces toxytricini
1uniprot[Pubmed] 17205043
Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.(J. Microbiol.) [2006]
23
F4FBT5_VERMA
(F4FBT5)
[query] 1 - 85 (85)
[subject] 1 - 85 (85)
7e-14 80.9 52%
Product
Putative uncharacterized protein
Gene
VAB18032_18165
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
24
Q9AMJ1_STRAT
(Q9AMJ1)
[query] 4 - 78 (85)
[subject] 6 - 80 (88)
9e-14 80.5 55%
Product
Putative acyl carrier protein SimA3
Sim4
Gene
simA3
sim4
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
26
Q54219_STRGR
(Q54219)
Jump to Griseu_00030
[query] 4 - 80 (85)
[subject] 6 - 82 (89)
2e-13 79.3 55%
Product
Acyl carrier protein
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
27
F2RC17_STRVP
(F2RC17)
[query] 4 - 79 (85)
[subject] 6 - 81 (89)
2e-13 79   55%
Product
Acyl carrier protein
Gene
SVEN_5982
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
28
Q56165_9ACTO
(Q56165)
Jump to Jado_00100
[query] 4 - 79 (85)
[subject] 6 - 81 (89)
2e-13 79   55%
Product
Acyl carrier protein
Gene
acp
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
30
Q7WT30_9ACTO
(Q7WT30)
Jump to Medem_00120
[query] 6 - 78 (85)
[subject] 10 - 82 (91)
3e-13 79   55%
Product
Acyl carrier protein (ACP)
Gene
med-ORF23
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
31
D5MRI6_9ACTO
(D5MRI6)
[query] 4 - 79 (85)
[subject] 6 - 81 (87)
3e-13 78.6 55%
Product
Putative acyl carrier protein
Gene
hrbM
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
32
D6MSY3_9ACTO
(D6MSY3)
[query] 1 - 78 (85)
[subject] 1 - 78 (85)
3e-13 78.6 51%
Product
SsfC
Gene
ssfC
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
34
Q2HR22_9ACTO
(Q2HR22)
Jump to Sch475_00360
[query] 4 - 78 (85)
[subject] 6 - 80 (89)
3e-13 78.6 55%
Product
Putative acyl carrier protein
Gene
schP6
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
36
Q54175_STRFR
(Q54175)
Jump to Urd_00140
[query] 4 - 78 (85)
[subject] 6 - 80 (89)
1e-12 76.6 52%
Product
Putative acyl carrier protein
Gene
UrdC
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
37
D2AY46_STRRD
(D2AY46)
[query] 4 - 78 (85)
[subject] 7 - 81 (86)
1e-12 76.6 53%
Product
Putative uncharacterized protein
Gene
Sros_4152
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
38
Q56HA0_STRAU
(Q56HA0)
[query] 2 - 78 (85)
[subject] 9 - 85 (94)
2e-12 76.3 52%
Product
Aur1F
Gene
aur1F
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
40
Q47QL1_THEFY
(Q47QL1)
[query] 4 - 84 (85)
[subject] 6 - 86 (86)
2e-12 76.3 53%
Product
Actinorhodin polyketide synthase acyl carrier protein / 3-oxoacyl-ACP synthase acyl carrier protein
Gene
Tfu_1220
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
41
D9UBS9_STRPR
(D9UBS9)
[query] 1 - 80 (85)
[subject] 1 - 80 (87)
2e-12 76.3 51%
Product
Putative acyl carrier protein
Gene
cpp5
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
43
Q2J5E7_FRASC
(Q2J5E7)
[query] 4 - 76 (85)
[subject] 6 - 78 (98)
2e-12 75.9 55%
Product
Phosphopantetheine-binding
Gene
Francci3_4147
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
44
C7PWQ7_CATAD
(C7PWQ7)
[query] 4 - 79 (85)
[subject] 6 - 81 (102)
2e-12 75.5 53%
Product
Phosphopantetheine-binding
Gene
Caci_6487
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
45
E2D2I6_9BACT
(E2D2I6)
[query] 4 - 78 (85)
[subject] 1 - 72 (145)
3e-12 75.5 52%
Product
Acyl carrier protein
Gene
 
Organism
uncultured soil bacterium
1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]
46
Q9ZGD5_STRCY
(Q9ZGD5)
Jump to Lando_00050
[query] 1 - 78 (85)
[subject] 3 - 80 (89)
3e-12 75.5 53%
Product
Acyl carrier protein homolog
Gene
lanC
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
49
Q9XDZ8_9ACTO
(Q9XDZ8)
[query] 1 - 78 (85)
[subject] 1 - 78 (88)
6e-12 74.3 49%
Product
Polyketide synthase
Gene
 
Organism
Actinomadura verrucosospora
1uniprot[Pubmed] 10347064 [Medline] 99278093
Development of a self-cloning system for Actinomadura verrucosospora and identification of polyketide synthase genes essential for production of the angucyclic antibiotic pradimicin.(Appl. Environ. Microbiol.) [1999]
51
B6SEF3_9ACTO
(B6SEF3)
Jump to Alnu_00080
[query] 4 - 85 (85)
[subject] 3 - 84 (84)
7e-12 73.9 49%
Product
AlnN acyl carrier protein
Gene
alnN
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
52
Q54996_9ACTO
(Q54996)
Jump to Fren_00140
[query] 1 - 84 (85)
[subject] 1 - 83 (83)
9e-12 73.9 50%
Product
Acyl carrier protein
Gene
frnN
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
2uniprot[Pubmed] 12705828 [Medline] 22592266
Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein.(Biochemistry) [2003]
[pubmed all]
53
Q6VMI9_STRAM
(Q6VMI9)
[query] 4 - 85 (85)
[subject] 6 - 89 (89)
1e-11 73.6 50%
Product
Putative acyl carrier protein
Gene
alpC
DSMT0183
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
54
Q1RQS2_STRAM
(Q1RQS2)
[query] 4 - 85 (85)
[subject] 6 - 89 (89)
1e-11 73.6 50%
Product
Putative acyl carrier protein
Gene
alpC
SAMT0163
SAMT0164
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
55
A8KQY0_9ACTO
(A8KQY0)
Jump to Ello_00130
[query] 4 - 78 (85)
[subject] 2 - 76 (83)
1e-11 73.2 48%
Product
Acyl carrier protein
Gene
elmM
Organism
Streptomyces olivaceus
1uniprot[Pubmed] 18310024
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008]
57
Q48377_KIBAR
(Q48377)
[query] 4 - 83 (85)
[subject] 3 - 82 (82)
2e-11 72.8 48%
Product
ArdIorf3
Gene
ardIorf3
Organism
Kibdelosporangium aridum
1uniprot[Pubmed] 7987007 [Medline] 95078455
Cloning and nucleotide sequence of a region of the Kibdelosporangium aridum genome homologous to polyketide biosynthetic genes.(DNA Seq.) [1994]
59
D1A6T5_THECD
(D1A6T5)
[query] 1 - 78 (85)
[subject] 1 - 77 (82)
2e-11 72.8 54%
Product
Phosphopantetheine-binding protein
Gene
Tcur_2794
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
61
Q67G32_9ACTO
(Q67G32)
Jump to Heda_00260
[query] 1 - 85 (85)
[subject] 235 - 319 (319)
2e-11 72.4 48%
Product
Putative bifunctional cyclase dehydratase and ACP fusion
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
62
Q8VWB1_9ACTO
(Q8VWB1)
[query] 1 - 85 (85)
[subject] 1 - 84 (91)
3e-11 72   47%
Product
AknD
Gene
aknD
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
63
D2SZ01_MICEC
(D2SZ01)
[query] 4 - 85 (85)
[subject] 1 - 82 (82)
3e-11 72   48%
Product
Acyl carrier protein
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
64
Q3S8R2_STRRM
(Q3S8R2)
Jump to Oxtet_00040
[query] 16 - 78 (85)
[subject] 16 - 78 (95)
5e-11 71.2 49%
Product
OxyC
Gene
oxyC
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
65
ACPX_STRRM
(P43677)
[query] 16 - 78 (85)
[subject] 16 - 78 (95)
5e-11 71.2 49%
Product
Oxytetracycline polyketide synthase acyl carrier protein
Gene
 
Organism
Streptomyces rimosus
1uniprot[Pubmed] 8163168 [Medline] 94215879
Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus.(Gene) [1994]
67
C7QAF4_CATAD
(C7QAF4)
[query] 1 - 80 (85)
[subject] 6 - 85 (92)
1e-10 70.1 49%
Product
Phosphopantetheine-binding
Gene
Caci_3548
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
68
Q9L549_9ACTO
(Q9L549)
Jump to Acla_00090
[query] 1 - 85 (85)
[subject] 1 - 84 (91)
2e-10 69.3 46%
Product
AknD
Gene
aknD
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
69
ACPX_STRGA
(P12884)
[query] 1 - 82 (85)
[subject] 1 - 79 (83)
3e-10 68.9 47%
Product
Tetracenomycin C polyketide synthase acyl carrier protein
Gene
tcmM
Organism
Streptomyces glaucescens
1uniprot[Pubmed] 2684656 [Medline] 90060035
Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.(EMBO J.) [1989]
2uniprot[Pubmed] 1548230 [Medline] 92193265
Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.(J. Bacteriol.) [1992]
[pubmed all]
70
Q93H99_STRAW
(Q93H99)
[query] 1 - 78 (85)
[subject] 1 - 79 (86)
4e-10 68.2 47%
Product
Acyl carrier protein
Putative acyl carrier protein
Gene
pks9-1
SAV2373
SAV_2373
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
72
Q2PA09_9ACTO
(Q2PA09)
Jump to Stref_00060
[query] 16 - 83 (85)
[subject] 16 - 84 (86)
5e-10 68.2 57%
Product
Acyl carrier protein
Gene
stfS
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
73
D3U9Z5_9ACTO
(D3U9Z5)
[query] 1 - 84 (85)
[subject] 51 - 134 (134)
6e-10 67.8 46%
Product
Acyl carrier protein
Gene
sfaO
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
74
A7DWI7_STRTE
(A7DWI7)
[query] 1 - 84 (85)
[subject] 1 - 84 (86)
1e-09 66.2 46%
Product
Putative acyl carrier protein (ACP)
Gene
llpD
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
77
C0JWB6_9ACTO
(C0JWB6)
Jump to Polk_00210
[query] 1 - 78 (85)
[subject] 1 - 78 (85)
3e-09 65.1 46%
Product
PokP3
Gene
pokP3
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
78
Q2J5J5_FRASC
(Q2J5J5)
[query] 1 - 81 (85)
[subject] 1 - 81 (87)
4e-09 65.1 46%
Product
Phosphopantetheine-binding
Gene
Francci3_4099
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
79
Q2MGC9_STRGR
(Q2MGC9)
Jump to Fred_00100
[query] 1 - 82 (85)
[subject] 1 - 82 (84)
5e-09 64.3 40%
Product
ACP
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 16305230
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005]
80
B0LJ41_9ACTO
(B0LJ41)
[query] 1 - 79 (85)
[subject] 1 - 79 (93)
8e-09 63.9 42%
Product
Lcz24
Gene
lcz24
Organism
Streptomyces sanglieri
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
81
ACPX_STRCM
(P41174)
[query] 4 - 78 (85)
[subject] 6 - 79 (88)
9e-09 63.5 51%
Product
Monensin polyketide synthase acyl carrier protein
Gene
 
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 1508151 [Medline] 92374994
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992]
83
E2EKK1_9ACTO
(E2EKK1)
[query] 2 - 80 (85)
[subject] 3 - 81 (85)
1e-08 63.2 42%
Product
Acyl carrier protein
Gene
sanH
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
84
Q54497_STRNO
(Q54497)
Jump to Nogl_00390
[query] 3 - 85 (85)
[subject] 4 - 86 (86)
2e-08 62.8 47%
Product
Snoa3
Gene
snoa3
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
86
D7RFJ7_AMYOR
(D7RFJ7)
[query] 4 - 78 (85)
[subject] 6 - 78 (86)
3e-08 62   48%
Product
Putative acyl carrier protein
Gene
bexC
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
87
Q7X2H6_9ACTO
(Q7X2H6)
Jump to Gilvo_00200
[query] 2 - 85 (85)
[subject] 3 - 86 (89)
3e-08 62   45%
Product
Putative acyl carrier protein
Gene
gilC
Organism
Streptomyces griseoflavus
1uniprot[Pubmed] 12822997 [Medline] 22708304
The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003]
88
D8I4L9_AMYMU
(D8I4L9)
[query] 4 - 80 (85)
[subject] 2 - 77 (81)
8e-08 60.8 44%
Product
3-oxoacyl-ACP synthase acylcarrier protein
Gene
actI
AMED_5433
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
89
Q9F6D5_9ACTO
(Q9F6D5)
Jump to R1128_00070
[query] 1 - 85 (85)
[subject] 1 - 85 (86)
9e-08 60.5 44%
Product
Acyl carrier protein
Gene
zhuG
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
93
B0LJ07_9ACTO
(B0LJ07)
[query] 1 - 78 (85)
[subject] 1 - 78 (92)
2e-07 59.3 44%
Product
Lct24
Gene
lct24
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
94
Q9ZAU0_STRPE
(Q9ZAU0)
Jump to Adria_00040
[query] 1 - 78 (85)
[subject] 1 - 77 (84)
4e-07 58.5 45%
Product
Daunorubicin acyl carrier protein
Gene
dpsG
Organism
Streptomyces peucetius
1uniprot[Pubmed] 9864344 [Medline] 99084971
Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene.(J. Bacteriol.) [1999]
95
C7N0D3_SACVD
(C7N0D3)
[query] 1 - 84 (85)
[subject] 1 - 84 (89)
4e-07 58.2 37%
Product
Acyl carrier protein
Gene
Svir_33710
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
96
Q53878_STRS5
(Q53878)
Jump to Dauno_00020
[query] 1 - 78 (85)
[subject] 1 - 77 (84)
5e-07 57.8 45%
Product
Acyl carrier protein
Gene
dauA(g)
Organism
Streptomyces sp. (strain C5)
1uniprot[Pubmed] 8655529 [Medline] 96236066
Cloning, sequencing, and analysis of aklaviketone reductase from Streptomyces sp. strain C5.(J. Bacteriol.) [1996]
97
Q53673_STRAA
(Q53673)
Jump to Mith_00160
[query] 4 - 83 (85)
[subject] 1 - 80 (85)
6e-07 57.8 41%
Product
Acyl carrier protein
Gene
mtmS
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
98
E1ARN2_STRAU
(E1ARN2)
[query] 1 - 78 (85)
[subject] 1 - 78 (89)
1e-06 56.2 48%
Product
Putative acyl carrier protein
Gene
sa22
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
99
O32453_9ACTO
(O32453)
[query] 5 - 79 (85)
[subject] 7 - 81 (87)
2e-06 55.8 53%
Product
ORF 3
PdmC
Gene
pdmC
Organism
Actinomadura hibisca
1uniprot[Pubmed] 9339544 [Medline] 97480928
Cloning and nucleotide sequence of the putative polyketide synthase genes for pradimicin biosynthesis from Actinomadura hibisca.(Biosci. Biotechnol. Biochem.) [1997]
100
Q8KSY8_9ACTO
(Q8KSY8)
Jump to Griseo_00040
[query] 13 - 78 (85)
[subject] 12 - 77 (86)
3e-06 55.5 45%
Product
Putative acyl carrier protein GrhC
Gene
grhC
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]