| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q56167_9ACTO (Q56167) |
|
|
1e-180 |
635 |
100% |
|
- Product
- Bifunctional cyclase/dehydrase
- Gene
-
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 7881555 [Medline] 95187308 Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994] | 2uniprot Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999] |
|
2
|
F2RC19_STRVP (F2RC19) |
|
|
1e-167 |
592 |
98% |
|
- Product
- Bifunctional cyclase or dehydrase
- Gene
- SVEN_5984
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
3
|
Q9RPB1_STRFR (Q9RPB1) |
|
|
1e-152 |
540 |
85% |
|
- Product
- Cyclase
- Gene
- urdL
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000] |
|
4
|
D5MRI9_9ACTO (D5MRI9) |
|
|
1e-140 |
503 |
78% |
|
- Product
- Putative aromatase
- Gene
- hrbP
- Organism
- Streptomyces sp. 2238-SVT4
|
1uniprot[Pubmed] 20453135 Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010] |
|
6
|
Q93LY0_9ACTO (Q93LY0) |
|
|
1e-140 |
501 |
79% |
|
- Product
- Putative bifunctional aromatase PgaL
- Gene
- pgaL
- Organism
- Streptomyces sp. PGA64
|
1uniprot[Pubmed] 12654660 [Medline] 22540650 Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003] | 2uniprot[Pubmed] 15515887 Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004] | [pubmed all]
|
9
|
Q93M00_STRAU (Q93M00) |
|
|
1e-137 |
493 |
79% |
|
- Product
- Cyclase/dehydratase-like protein
- Gene
- aur2F
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 15497441 Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004] |
|
10
|
Q56H98_STRAU (Q56H98) |
|
|
1e-137 |
493 |
80% |
|
- Product
- Aur1H
- Gene
- aur1H
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 12384301 [Medline] 22271582 Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002] | 2uniprot[Pubmed] 16079347 Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005] | 3uniprot[Pubmed] 20466770 The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010] | [pubmed all]
|
11
|
Q9ZGD3_STRCY (Q9ZGD3) |
|
|
1e-135 |
484 |
76% |
|
- Product
- Cyclase homolog
- Gene
- lanL
- Organism
- Streptomyces cyanogenus
|
1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999] |
|
12
|
Q54221_STRGR (Q54221) |
|
|
1e-133 |
480 |
77% |
|
- Product
- Putative cyclase/dehydrase
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 8169211 [Medline] 94222841 Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994] |
|
15
|
Q2HR24_9ACTO (Q2HR24) |
|
|
1e-124 |
449 |
69% |
|
- Product
- Putative aromatase
- Gene
- schP4
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
16
|
Q9AMI9_STRAT (Q9AMI9) |
|
|
1e-120 |
434 |
70% |
|
- Product
- Putative cyclase/dehydrase SimA5
Sim6
- Gene
- simA5
sim6
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 11959542 [Medline] 21955989 Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002] | 2uniprot[Pubmed] 12115055 [Medline] 22109063 Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002] | [pubmed all]
|
17
|
Q6VMJ1_STRAM (Q6VMJ1) |
|
|
1e-119 |
432 |
69% |
|
- Product
- Putative bifunctional cyclase/dehydrase
Putative cyclase/dehydratase
- Gene
- alpE
DSMT0181
- Organism
- Streptomyces ambofaciens
|
1uniprot[Pubmed] 14742212 Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004] | 2uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] | [pubmed all]
|
18
|
Q1RQS4_STRAM (Q1RQS4) |
|
|
1e-119 |
432 |
69% |
|
- Product
- Putative cyclase/dehydratase
- Gene
- alpE
SAMT0161 SAMT0162
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 3uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] | [pubmed all]
|
19
|
D7RFJ9_AMYOR (D7RFJ9) |
|
|
1e-119 |
432 |
70% |
|
- Product
- Putative cyclase
- Gene
- bexL
- Organism
- Amycolatopsis orientalis subsp. vinearia
|
1uniprot[Pubmed] 20443562 A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010] |
|
21
|
D2XDY3_9PSEU (D2XDY3) |
|
|
1e-118 |
430 |
70% |
|
- Product
- AzicE
- Gene
- azicE
- Organism
- Kibdelosporangium sp. MJ126-NF4
|
1uniprot[Pubmed] 19928906 Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009] |
|
22
|
C7QAF6_CATAD (C7QAF6) |
|
|
1e-113 |
414 |
65% |
|
- Product
- Cyclase/dehydrase
- Gene
- Caci_3550
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
23
|
C4NYK3_9ACTO (C4NYK3) |
|
|
1e-113 |
413 |
66% |
|
- Product
- SaqL
- Gene
- saqL
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
25
|
Q47QK9_THEFY (Q47QK9) |
|
|
1e-104 |
384 |
60% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- Tfu_1222
- Organism
- Thermobifida fusca (strain YX)
|
1uniprot[Pubmed] 17209016 Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007] |
|
26
|
Q2J5F1_FRASC (Q2J5F1) |
|
|
1e-102 |
377 |
58% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- Francci3_4143
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
29
|
CYPK_STRCM (P41178) |
|
|
9e-91 |
338 |
60% |
|
- Product
- Granaticin polyketide synthase bifunctional cyclase/dehydratase
ORF4
- Gene
-
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 1508151 [Medline] 92374994 Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992] |
|
30
|
B7TX46_9ACTO (B7TX46) |
|
|
5e-90 |
335 |
75% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 6G13
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
33
|
Q7WT27_9ACTO (Q7WT27) |
|
|
3e-87 |
326 |
53% |
|
- Product
- First ring aromatase (ARO)
- Gene
- med-ORF19
- Organism
- Streptomyces sp. AM-7161
|
1uniprot Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003] |
|
35
|
Q54490_STRNO (Q54490) |
|
|
3e-85 |
319 |
50% |
|
- Product
- SnoaE
- Gene
- snoaE
- Organism
- Streptomyces nogalater
|
1uniprot[Pubmed] 8668120 [Medline] 96242142 A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996] | 2uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] | 3uniprot[Pubmed] 8760909 [Medline] 96349102 Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996] | [pubmed all]
|
36
|
D7BZR8_STRBB (D7BZR8) |
|
|
3e-85 |
319 |
54% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- SBI_06853
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
38
|
B3VNY8_9ACTO (B3VNY8) |
|
|
5e-83 |
312 |
70% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Micromonospora sp. 8g107
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
39
|
D6MSV2_9ACTO (D6MSV2) |
|
|
3e-81 |
306 |
50% |
|
- Product
- SsfY1
- Gene
- ssfY1
- Organism
- Streptomyces sp. SF2575
|
1uniprot[Pubmed] 19908837 Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009] |
|
40
|
Q8VWB6_9ACTO (Q8VWB6) |
|
|
3e-81 |
306 |
51% |
|
- Product
- AknE1
- Gene
- aknE1
- Organism
- Streptomyces galilaeus
|
1uniprot[Pubmed] 12399480 [Medline] 22286521 Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002] |
|
41
|
Q9L554_9ACTO (Q9L554) |
|
|
1e-80 |
304 |
51% |
|
- Product
- AknE1
- Gene
- aknE1
- Organism
- Streptomyces galilaeus
|
1uniprot[Pubmed] 12137949 [Medline] 22133312 Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002] |
|
42
|
Q4R0M7_STRCX (Q4R0M7) |
|
|
2e-80 |
303 |
50% |
|
- Product
- ChaF protein
- Gene
- chaF
- Organism
- Streptomyces chartreusis
|
1uniprot[Pubmed] 15911378 Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005] |
|
45
|
B3VNY6_9ACTO (B3VNY6) |
|
|
6e-78 |
295 |
70% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 15MN1
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
54
|
B7TX44_9ACTO (B7TX44) |
|
|
1e-76 |
291 |
67% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 6G6
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
55
|
B7TX48_9ACTO (B7TX48) |
|
|
1e-76 |
290 |
67% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 6G17
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
56
|
B7TX47_9ACTO (B7TX47) |
|
|
1e-76 |
290 |
67% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 6G8
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
59
|
B3VNY7_9ACTO (B3VNY7) |
|
|
1e-76 |
290 |
68% |
|
- Product
- Putative cyclase/dehydratase
- Gene
-
- Organism
- Streptomyces sp. 4MN1
|
1uniprot[Pubmed] 21287404 A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011] |
|
71
|
Q9X464_STRAE (Q9X464) |
|
|
2e-75 |
286 |
48% |
|
- Product
- Aromatase
- Gene
- ncnD
- Organism
- Streptomyces arenae
|
1uniprot[Pubmed] 10206788 [Medline] 99217421 Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999] |
|
73
|
D9UBK6_STRPR (D9UBK6) |
|
|
5e-75 |
285 |
48% |
|
- Product
- Putative cyclase
- Gene
- c104_07c
- Organism
- Streptomyces pristinaespiralis
|
1uniprot[Pubmed] 21342465 Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011] |
|
77
|
Q54811_STRPE (Q54811) |
|
|
2e-73 |
280 |
47% |
|
- Product
- Daunorubicin-doxorubicin polyketide synthase
- Gene
- dpsF
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 7828855 [Medline] 95129838 Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994] |
|
78
|
Q9FCM5_STRAT (Q9FCM5) |
|
|
3e-73 |
279 |
47% |
|
- Product
- Putative aromatase
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 11700358 [Medline] 21557167 A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001] |
|
79
|
Q55220_STRSQ (Q55220) |
|
|
9e-73 |
278 |
48% |
|
- Product
- Cyclase/dehydrase
- Gene
- dauA
- Organism
- Streptomyces sp
|
1uniprot[Pubmed] 7928998 [Medline] 95014072 Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.(J. Bacteriol.) [1994] |
|
80
|
D1A6S1_THECD (D1A6S1) |
|
|
4e-70 |
269 |
47% |
|
- Product
- Cyclase/dehydrase
- Gene
- Tcur_2780
- Organism
- Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
|
1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011] |
|
81
|
Q2J5J6_FRASC (Q2J5J6) |
|
|
1e-69 |
268 |
44% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- Francci3_4098
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
83
|
Q3S8Q5_STRRM (Q3S8Q5) |
|
|
6e-68 |
262 |
48% |
|
- Product
- OxyK
- Gene
- oxyK
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 16597959 Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006] |
|
85
|
CYPK_STRVN (P16560) |
|
|
8e-67 |
258 |
44% |
|
- Product
- Granaticin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- gra-orf4
- Organism
- Streptomyces violaceoruber
|
1uniprot[Pubmed] 2583128 [Medline] 90060034 Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989] | 2uniprot[Pubmed] 7476861 [Medline] 96027933 Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995] | 3uniprot[Pubmed] 9831526 [Medline] 99051446 The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998] | [pubmed all]
|
87
|
Q9ZG83_STRRM (Q9ZG83) |
|
|
1e-65 |
254 |
47% |
|
- Product
- Cyclase/aromatase
- Gene
- otcD1
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 10551844 [Medline] 20020252 Disruption of an aromatase/cyclase from the oxytetracycline gene cluster of Streptomyces rimosus results in production of novel polyketides with shorter chain lengths.(J. Biol. Chem.) [1999] | 2uniprot Characterisation of some genes involved in the early steps of the biosynthetic pathway for oxytetracycline in Streptomyces rimosus. [1994] |
|
88
|
CYPK_STRCO (Q02055) |
|
|
1e-62 |
244 |
43% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
ACTVII actI ORF4
- Gene
- SCO5090
SCBAC28G1.16
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 1527048 [Medline] 92406871 Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992] | 2uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | [pubmed all]
|
89
|
Q83X42_STRRO (Q83X42) |
|
|
2e-62 |
243 |
45% |
|
- Product
- Cyclase/aromatase
- Gene
- rocH
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|
91
|
Q79CP1_9ACTO (Q79CP1) |
|
|
7e-59 |
232 |
100% |
|
- Product
- Bifunctional cyclase/dehydrase
- Gene
-
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 8581159 [Medline] 96146057 Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae.(Microbiology) |
|
92
|
Q7X2H2_9ACTO (Q7X2H2) |
|
|
6e-56 |
222 |
41% |
|
- Product
- Putative cyclase/dehydratase
- Gene
- gilK
- Organism
- Streptomyces griseoflavus
|
1uniprot[Pubmed] 12822997 [Medline] 22708304 The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003] |
|
94
|
C7PWQ8_CATAD (C7PWQ8) |
|
|
5e-54 |
216 |
40% |
|
- Product
- Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
- Gene
- Caci_6488
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
96
|
Q54999_9ACTO (Q54999) |
|
|
1e-52 |
211 |
39% |
|
- Product
- Aromatase
- Gene
- frnQ
- Organism
- Streptomyces roseofulvus
|
1uniprot[Pubmed] 8181754 [Medline] 94237486 Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994] |
|
99
|
B6SEF5_9ACTO (B6SEF5) |
|
|
2e-49 |
200 |
36% |
|
- Product
- AlnQ aromatase
- Gene
- alnQ
- Organism
- Streptomyces sp. CM020
|
1uniprot[Pubmed] 18940666 Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008] |
|