BLAST table : R1128_00090

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q9F6D3_9ACTO
(Q9F6D3)		 
[query] 1 - 169 (169)
[subject] 1 - 169 (169)
 1e-90 335   100% Cyclase zhuI Streptomyces sp. R1128
2
 D9W8F6_9ACTO
(D9W8F6)		 
[query] 1 - 156 (169)
[subject] 1 - 155 (163)
 9e-48 193   63% Granaticin polyketide synthase bifunctional cyclase/dehydratase SSOG_02377 Streptomyces himastatinicus ATCC 53653
3
 E2D2J7_9BACT
(E2D2J7)		 
[query] 1 - 159 (169)
[subject] 114 - 266 (272)
 1e-39 166   53% Cyclase uncultured soil bacterium
4
 D9W8F0_9ACTO
(D9W8F0)		 
[query] 1 - 160 (169)
[subject] 6 - 166 (166)
 3e-35 152   51% Polyketide cyclase/dehydrase superfamily protein SSOG_02371 Streptomyces himastatinicus ATCC 53653
5
 Q47QK9_THEFY
(Q47QK9)		 
[query] 2 - 150 (169)
[subject] 7 - 144 (314)
 2e-18 95.9 39% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Tfu_1222 Thermobifida fusca (strain YX)
6
 C7QAF6_CATAD
(C7QAF6)		 
[query] 1 - 158 (169)
[subject] 6 - 152 (316)
 3e-18 95.1 37% Cyclase/dehydrase Caci_3550 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
7
 Q56H98_STRAU
(Q56H98)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (320)
 1e-17 93.2 37% Aur1H aur1H Streptomyces aureofaciens
8
 CYPK_STRCO
(Q02055)		 Jump to Actino_00210 
[query] 4 - 157 (169)
[subject] 9 - 148 (316)
 1e-17 93.2 40% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
ACTVII
actI ORF4		 SCO5090
SCBAC28G1.16		 Streptomyces coelicolor
9
 D7RFJ9_AMYOR
(D7RFJ9)		 
[query] 1 - 119 (169)
[subject] 1 - 117 (309)
 1e-17 92.8 42% Putative cyclase bexL Amycolatopsis orientalis subsp. vinearia
10
 D6EWA4_STRLI
(D6EWA4)		 
[query] 4 - 157 (169)
[subject] 9 - 148 (316)
 1e-17 92.8 40% Cyclase/dehydrase SSPG_02599 Streptomyces lividans TK24
11
 Q93M00_STRAU
(Q93M00)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (316)
 1e-17 92.8 37% Cyclase/dehydratase-like protein aur2F Streptomyces aureofaciens
12
 Q2HR24_9ACTO
(Q2HR24)		 Jump to Sch475_00340 
[query] 1 - 156 (169)
[subject] 3 - 147 (312)
 7e-17 90.9 38% Putative aromatase schP4 Streptomyces sp. SCC 2136
13
 D9UBK6_STRPR
(D9UBK6)		 
[query] 6 - 156 (169)
[subject] 11 - 150 (318)
(2 hsp)		 9e-17 90.1 39% Putative cyclase c104_07c Streptomyces pristinaespiralis
14
 B5HJY1_STRPR
(B5HJY1)		 
[query] 6 - 156 (169)
[subject] 11 - 150 (318)
(2 hsp)		 9e-17 90.1 39% Cyclase SSDG_05478 Streptomyces pristinaespiralis ATCC 25486
15
 Q93LY0_9ACTO
(Q93LY0)		 
[query] 1 - 150 (169)
[subject] 6 - 144 (314)
 1e-16 90.1 39% Putative bifunctional aromatase PgaL pgaL Streptomyces sp. PGA64
16
 Q4R0M7_STRCX
(Q4R0M7)		 Jump to Chart_00050 
[query] 1 - 111 (169)
[subject] 6 - 116 (322)
 1e-16 89.7 41% ChaF protein chaF Streptomyces chartreusis
17
 D1XRF3_9ACTO
(D1XRF3)		 
[query] 2 - 147 (169)
[subject] 7 - 141 (314)
 1e-16 89.7 39% Cyclase/dehydrase SACTEDRAFT_5263 Streptomyces sp. SA3_actE
18
 Q2J5J6_FRASC
(Q2J5J6)		 
[query] 6 - 155 (169)
[subject] 9 - 147 (319)
 1e-16 89.7 38% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Francci3_4098 Frankia sp. (strain CcI3)
19
 Q2J5F1_FRASC
(Q2J5F1)		 
[query] 2 - 155 (169)
[subject] 10 - 152 (318)
 1e-16 89.7 38% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Francci3_4143 Frankia sp. (strain CcI3)
20
 D6XAX1_9ACTO
(D6XAX1)		 
[query] 2 - 156 (169)
[subject] 9 - 152 (391)
 2e-16 89   38% Cyclase SSEG_11170 Streptomyces sviceus ATCC 29083
21
 Q54490_STRNO
(Q54490)		 Jump to Nogl_00320 
[query] 4 - 150 (169)
[subject] 13 - 148 (323)
 3e-16 89   36% SnoaE snoaE Streptomyces nogalater
22
 Q9RPB1_STRFR
(Q9RPB1)		 Jump to Urd_00160 
[query] 2 - 155 (169)
[subject] 4 - 146 (311)
 3e-16 88.6 36% Cyclase urdL Streptomyces fradiae
Streptomyces roseoflavus
23
 A1C174_9ACTO
(A1C174)		 Jump to Aran_00060 
[query] 3 - 167 (169)
[subject] 6 - 172 (314)
 5e-16 87.8 36% Cyclase Streptomyces echinatus
24
 E3T4B3_9ACTO
(E3T4B3)		 
[query] 5 - 155 (169)
[subject] 16 - 155 (328)
 6e-16 87.8 37% Aromatase gra-orf4 Streptomyces vietnamensis
25
 Q6ZZV8_STRAT
(Q6ZZV8)		 Jump to Ovied_00150 
[query] 2 - 155 (169)
[subject] 4 - 146 (315)
 8e-16 87   39% Aromatase ovmA Streptomyces antibioticus
26
 Q54221_STRGR
(Q54221)		 Jump to Griseu_00050 
[query] 1 - 156 (169)
[subject] 6 - 150 (319)
 1e-15 87   36% Putative cyclase/dehydrase Streptomyces griseus
27
 Q54999_9ACTO
(Q54999)		 Jump to Fren_00170 
[query] 4 - 164 (169)
[subject] 14 - 161 (331)
 2e-15 86.3 35% Aromatase frnQ Streptomyces roseofulvus
28
 CYPK_STRVN
(P16560)		 Jump to Grana_00290 
[query] 5 - 155 (169)
[subject] 20 - 159 (324)
 2e-15 85.9 37% Granaticin polyketide synthase bifunctional cyclase/dehydratase gra-orf4 Streptomyces violaceoruber
29
 D7BZR8_STRBB
(D7BZR8)		 
[query] 6 - 155 (169)
[subject] 11 - 149 (324)
 2e-15 85.9 38% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase SBI_06853 Streptomyces bingchenggensis (strain BCW-1)
30
 C4NYK3_9ACTO
(C4NYK3)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (314)
 3e-15 85.1 34% SaqL saqL Micromonospora sp. Tu 6368
31
 F6K0W1_9BACT
(F6K0W1)		 
[query] 2 - 150 (169)
[subject] 7 - 144 (316)
 5e-15 84.7 35% Aromatase uncultured bacterium BAC AB649/1850
32
 Q84CJ3_9ACTO
(Q84CJ3)		 
[query] 2 - 155 (169)
[subject] 4 - 146 (311)
 5e-15 84.7 35% Cyclase/dehydratase-like protein kinD Streptomyces murayamaensis
33
 Q6VMJ1_STRAM
(Q6VMJ1)		 
[query] 2 - 150 (169)
[subject] 4 - 141 (314)
 9e-15 83.6 38% Putative bifunctional cyclase/dehydrase
Putative cyclase/dehydratase		 alpE
DSMT0181		 Streptomyces ambofaciens
34
 Q1RQS4_STRAM
(Q1RQS4)		 
[query] 2 - 150 (169)
[subject] 4 - 141 (314)
 9e-15 83.6 38% Putative cyclase/dehydratase alpE
SAMT0161
SAMT0162		 Streptomyces ambofaciens ATCC 23877
35
 D1H099_9ACTO
(D1H099)		 
[query] 5 - 155 (169)
[subject] 10 - 149 (314)
 1e-14 83.6 37% Putative bifunctional cyclase/dehydratase chryK Streptomyces albaduncus
36
 D9W5A6_9ACTO
(D9W5A6)		 
[query] 1 - 150 (169)
[subject] 6 - 144 (314)
 1e-14 83.2 35% Aur1H SSNG_07336 Streptomyces sp. C
37
 C7PWQ8_CATAD
(C7PWQ8)		 
[query] 6 - 148 (169)
[subject] 20 - 156 (330)
 1e-14 83.2 33% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Caci_6488 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
38
 D6MSV2_9ACTO
(D6MSV2)		 
[query] 2 - 159 (169)
[subject] 7 - 153 (314)
 1e-14 83.2 37% SsfY1 ssfY1 Streptomyces sp. SF2575
39
 D5MRI9_9ACTO
(D5MRI9)		 
[query] 2 - 156 (169)
[subject] 4 - 147 (311)
 1e-14 83.2 37% Putative aromatase hrbP Streptomyces sp. 2238-SVT4
40
 Q7WT27_9ACTO
(Q7WT27)		 Jump to Medem_00150 
[query] 2 - 156 (169)
[subject] 7 - 150 (318)
 3e-14 81.6 35% First ring aromatase (ARO) med-ORF19 Streptomyces sp. AM-7161
41
 D9UKN8_9ACTO
(D9UKN8)		 
[query] 4 - 164 (169)
[subject] 14 - 161 (331)
 4e-14 81.6 34% Aromatase SSLG_05754 Streptomyces sp. SPB78
42
 Q55220_STRSQ
(Q55220)		 Jump to Dauno_00130 
[query] 1 - 150 (169)
[subject] 6 - 144 (315)
 4e-14 81.6 36% Cyclase/dehydrase dauA Streptomyces sp
43
 D2XDY3_9PSEU
(D2XDY3)		 
[query] 1 - 156 (169)
[subject] 6 - 150 (316)
 4e-14 81.3 35% AzicE azicE Kibdelosporangium sp. MJ126-NF4
44
 Q9FCM5_STRAT
(Q9FCM5)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (318)
 5e-14 81.3 35% Putative aromatase Streptomyces antibioticus
45
 D9T2A8_MICAI
(D9T2A8)		 
[query] 2 - 119 (169)
[subject] 4 - 119 (310)
 7e-14 80.9 39% Polyketide cyclase/dehydrase Micau_4011 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
46
 E8RWS1_MICSL
(E8RWS1)		 
[query] 2 - 119 (169)
[subject] 4 - 119 (310)
 7e-14 80.9 39% Polyketide cyclase/dehydrase ML5_4410 Micromonospora sp. (strain L5)
47
 D1H0K2_9ACTO
(D1H0K2)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (315)
 1e-13 79.7 35% Putative aromatase/cyclase ravK Streptomyces sp. C23201NS3
48
 Q9AMI9_STRAT
(Q9AMI9)		 
[query] 1 - 161 (169)
[subject] 6 - 155 (315)
 1e-13 79.7 36% Putative cyclase/dehydrase SimA5
Sim6		 simA5
sim6		 Streptomyces antibioticus
49
 D3U1V0_9BACT
(D3U1V0)		 
[query] 5 - 111 (169)
[subject] 8 - 114 (316)
 2e-13 79.3 40% Aromatase uncultured soil bacterium V167
50
 Q9X464_STRAE
(Q9X464)		 Jump to Naphcy_00040 
[query] 3 - 150 (169)
[subject] 9 - 145 (315)
 2e-13 79   34% Aromatase ncnD Streptomyces arenae
51
 Q54811_STRPE
(Q54811)		 Jump to Adria_00240 
[query] 1 - 156 (169)
[subject] 6 - 150 (315)
 2e-13 79   35% Daunorubicin-doxorubicin polyketide synthase dpsF Streptomyces peucetius
52
 E3J3Q0_FRASU
(E3J3Q0)		 
[query] 6 - 150 (169)
[subject] 20 - 153 (341)
 4e-13 78.2 36% Polyketide cyclase/dehydrase FraEuI1c_1320 Frankia sp. (strain EuI1c)
53
 B3VNY8_9ACTO
(B3VNY8)		 
[query] 30 - 155 (169)
[subject] 1 - 115 (214)
 8e-13 77.4 39% Putative cyclase/dehydratase Micromonospora sp. 8g107
54
 A4X6Z8_SALTO
(A4X6Z8)		 
[query] 5 - 155 (169)
[subject] 10 - 149 (319)
 9e-13 77   35% Cyclase/dehydrase Strop_2197 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
55
 Q84CH8_9ACTO
(Q84CH8)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (314)
 1e-12 77   35% Cyclase-like protein pd2D Streptomyces sp. WP 4669
56
 E8W959_STRFA
(E8W959)		 
[query] 4 - 126 (169)
[subject] 38 - 160 (347)
 1e-12 76.6 41% Polyketide cyclase/dehydrase Sfla_5325 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
57
 F2RC19_STRVP
(F2RC19)		 
[query] 2 - 155 (169)
[subject] 4 - 146 (311)
 2e-12 76.3 35% Bifunctional cyclase or dehydrase SVEN_5984 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
58
 B3VP10_9BACT
(B3VP10)		 
[query] 31 - 155 (169)
[subject] 1 - 114 (213)
 7e-12 73.9 38% Putative cyclase/dehydratase uncultured bacterium
59
 CYPK_STRCM
(P41178)		 
[query] 2 - 110 (169)
[subject] 4 - 112 (304)
 9e-12 73.6 39% Granaticin polyketide synthase bifunctional cyclase/dehydratase
ORF4		 Streptomyces cinnamonensis
60
 D6K4Q8_9ACTO
(D6K4Q8)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (161)
 1e-11 73.2 32% Putative uncharacterized protein SSTG_02039 Streptomyces sp. e14
61
 Q9ZGD3_STRCY
(Q9ZGD3)		 Jump to Lando_00070 
[query] 1 - 155 (169)
[subject] 3 - 153 (319)
 6e-11 71.2 35% Cyclase homolog lanL Streptomyces cyanogenus
62
 Q7X2H2_9ACTO
(Q7X2H2)		 Jump to Gilvo_00220 
[query] 6 - 168 (169)
[subject] 10 - 161 (316)
 1e-10 70.1 30% Putative cyclase/dehydratase gilK Streptomyces griseoflavus
63
 D9W5B3_9ACTO
(D9W5B3)		 
[query] 1 - 155 (169)
[subject] 1 - 144 (317)
 2e-10 69.3 33% Cyclase SSNG_07343 Streptomyces sp. C
64
 Q8VWB6_9ACTO
(Q8VWB6)		 
[query] 4 - 111 (169)
[subject] 8 - 115 (450)
 6e-10 67.8 36% AknE1 aknE1 Streptomyces galilaeus
65
 Q3S8Q5_STRRM
(Q3S8Q5)		 Jump to Oxtet_00110 
[query] 6 - 155 (169)
[subject] 11 - 149 (317)
 6e-10 67.8 33% OxyK oxyK Streptomyces rimosus
66
 Q56167_9ACTO
(Q56167)		 Jump to Jado_00120 
[query] 2 - 155 (169)
[subject] 4 - 145 (310)
 7e-10 67.4 34% Bifunctional cyclase/dehydrase Streptomyces venezuelae
67
 Q9ZG83_STRRM
(Q9ZG83)		 
[query] 6 - 155 (169)
[subject] 11 - 149 (297)
 7e-10 67.4 33% Cyclase/aromatase otcD1 Streptomyces rimosus
68
 B5G889_9ACTO
(B5G889)		 
[query] 4 - 111 (169)
[subject] 8 - 115 (450)
 1e-09 67   37% Granaticin polyketide synthase bifunctional cyclase/dehydratase SSBG_00497 Streptomyces sp. SPB74
69
 Q9L554_9ACTO
(Q9L554)		 Jump to Acla_00040 
[query] 4 - 111 (169)
[subject] 8 - 115 (450)
 1e-09 66.6 36% AknE1 aknE1 Streptomyces galilaeus
70
 Q9F6E5_STRCU
(Q9F6E5)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (159)
 2e-09 65.9 32% PKSA putative cyclase I Streptomyces collinus
71
 B7TX58_9ACTO
(B7TX58)		 
[query] 30 - 161 (169)
[subject] 1 - 120 (216)
 3e-09 65.1 37% Putative cyclase/dehydratase Streptomyces sp. MS7-1
72
 Q935Z5_9ACTO
(Q935Z5)		 
[query] 6 - 112 (169)
[subject] 11 - 117 (452)
 4e-09 64.7 36% RdmK rdmK Streptomyces purpurascens
73
 D1A6S1_THECD
(D1A6S1)		 
[query] 1 - 156 (169)
[subject] 25 - 169 (340)
 6e-09 64.3 30% Cyclase/dehydrase Tcur_2780 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
74
 D9XXA4_9ACTO
(D9XXA4)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (160)
 9e-09 63.5 30% Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN SSRG_00594 Streptomyces griseoflavus Tu4000
75
 E8S3J6_MICSL
(E8S3J6)		 
[query] 3 - 114 (169)
[subject] 86 - 197 (235)
 1e-08 63.5 36% Cyclase/dehydrase ML5_4897 Micromonospora sp. (strain L5)
76
 D6AV06_STRFL
(D6AV06)		 
[query] 3 - 111 (169)
[subject] 4 - 113 (293)
 1e-08 63.5 33% Cyclase I SSGG_03668 Streptomyces roseosporus NRRL 15998
77
 Q93HL9_STRAW
(Q93HL9)		 
[query] 3 - 159 (169)
[subject] 4 - 149 (159)
 1e-08 63.2 26% Cyclase I
Putative cyclase I		 sppD
SAV2841
SAV_2841		 Streptomyces avermitilis
78
 A4X7U8_SALTO
(A4X7U8)		 
[query] 3 - 165 (169)
[subject] 86 - 237 (239)
 1e-08 63.2 31% Cyclase/dehydrase Strop_2502 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
79
 D5ZY73_9ACTO
(D5ZY73)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (160)
 2e-08 63.2 29% Cyclase I SSFG_06311 Streptomyces ghanaensis ATCC 14672
80
 Q83X42_STRRO
(Q83X42)		 
[query] 6 - 159 (169)
[subject] 14 - 156 (321)
 2e-08 62.4 32% Cyclase/aromatase rocH Streptomyces rochei
Streptomyces parvullus
81
 D9SXY1_MICAI
(D9SXY1)		 
[query] 3 - 114 (169)
[subject] 86 - 197 (235)
 2e-08 62.4 36% Cyclase/dehydrase Micau_3498 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
82
 Q8KSW2_9ACTO
(Q8KSW2)		 Jump to Griseo_00300 
[query] 3 - 111 (169)
[subject] 4 - 112 (402)
 3e-08 62   34% Putative bifunctional cyclase/3-oxoacyl-ACP reductase GrhT grhT Streptomyces sp. JP95
83
 Q2J931_FRASC
(Q2J931)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (162)
 3e-08 62   32% Cyclase/dehydrase Francci3_2853 Frankia sp. (strain CcI3)
84
 F2RIV3_STRVP
(F2RIV3)		 
[query] 3 - 93 (169)
[subject] 4 - 95 (159)
 5e-08 61.2 32% Aromatase WhiE VI SVEN_6793 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
85
 A2AXE4_STRCM
(A2AXE4)		 
[query] 6 - 138 (169)
[subject] 12 - 145 (373)
 7e-08 60.8 29% Putative polyketide cyclase/aromatase fnq5 Streptomyces cinnamonensis
86
 F4F9S5_VERMA
(F4F9S5)		 
[query] 3 - 114 (169)
[subject] 86 - 197 (244)
 7e-08 60.8 33% Cyclase/dehydrase VAB18032_23765 Verrucosispora maris (strain AB-18-032)
87
 A8M4V5_SALAI
(A8M4V5)		 
[query] 3 - 114 (169)
[subject] 86 - 197 (239)
 9e-08 60.5 37% Cyclase/dehydrase Sare_2686 Salinispora arenicola (strain CNS-205)
88
 E2PW01_STRCL
(E2PW01)		 
[query] 3 - 93 (169)
[subject] 4 - 95 (161)
 1e-07 60.1 37% Polyketide cyclase sppD
SCLAV_4918		 Streptomyces clavuligerus ATCC 27064 4.2.1.-
89
 D6EUH4_STRLI
(D6EUH4)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (159)
 2e-07 59.7 29% Polyketide cyclase SSPG_02368 Streptomyces lividans TK24
90
 CYPC_STRCO
(P23154)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (159)
 2e-07 59.7 29% Putative polyketide cyclase
WhiE ORF VI		 SCO5315
SC6G9.18		 Streptomyces coelicolor
91
 D3CRU2_9ACTO
(D3CRU2)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (162)
 3e-07 58.5 32% Cyclase/dehydrase FrEUN1fDRAFT_0259 Frankia sp. EUN1f
92
 Q0RHJ5_FRAAA
(Q0RHJ5)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (164)
 3e-07 58.5 29% Putative polyketide cyclase FRAAL4389 Frankia alni (strain ACN14a)
93
 B5HJN9_STRPR
(B5HJN9)		 
[query] 3 - 159 (169)
[subject] 4 - 149 (164)
 3e-07 58.5 28% Cyclase I SSDG_05411 Streptomyces pristinaespiralis ATCC 25486
94
 A7DWI6_STRTE
(A7DWI6)		 
[query] 3 - 141 (169)
[subject] 4 - 143 (155)
 4e-07 58.2 29% Putative polyketide cyclase llpCI Streptomyces tendae
95
 D7C2K5_STRBB
(D7C2K5)		 
[query] 3 - 161 (169)
[subject] 4 - 151 (154)
 4e-07 58.2 28% Putative polyketide cyclase I sppD
SBI_02767		 Streptomyces bingchenggensis (strain BCW-1)
96
 B3VNY6_9ACTO
(B3VNY6)		 
[query] 30 - 150 (169)
[subject] 1 - 110 (213)
 4e-07 58.2 35% Putative cyclase/dehydratase Streptomyces sp. 15MN1
97
 B7TX46_9ACTO
(B7TX46)		 
[query] 30 - 155 (169)
[subject] 1 - 115 (214)
 4e-07 58.2 33% Putative cyclase/dehydratase Streptomyces sp. 6G13
98
 B6SEF5_9ACTO
(B6SEF5)		 Jump to Alnu_00100 
[query] 2 - 156 (169)
[subject] 15 - 158 (331)
 6e-07 57.8 31% AlnQ aromatase alnQ Streptomyces sp. CM020
99
 D2AY47_STRRD
(D2AY47)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (160)
 6e-07 57.8 29% Putative uncharacterized protein Sros_4153 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
100
 D3CXU7_9ACTO
(D3CXU7)		 
[query] 3 - 147 (169)
[subject] 4 - 147 (498)
 6e-07 57.8 27% Cyclase/dehydrase FrEUN1fDRAFT_2367 Frankia sp. EUN1f
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q9F6D3_9ACTO
(Q9F6D3)		 
[query] 1 - 169 (169)
[subject] 1 - 169 (169)
 1e-90 335   100%
Product
Cyclase
Gene
zhuI
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
3
 E2D2J7_9BACT
(E2D2J7)		 
[query] 1 - 159 (169)
[subject] 114 - 266 (272)
 1e-39 166   53%
Product
Cyclase
Gene
 
Organism
uncultured soil bacterium
1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]
5
 Q47QK9_THEFY
(Q47QK9)		 
[query] 2 - 150 (169)
[subject] 7 - 144 (314)
 2e-18 95.9 39%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Tfu_1222
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
6
 C7QAF6_CATAD
(C7QAF6)		 
[query] 1 - 158 (169)
[subject] 6 - 152 (316)
 3e-18 95.1 37%
Product
Cyclase/dehydrase
Gene
Caci_3550
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
7
 Q56H98_STRAU
(Q56H98)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (320)
 1e-17 93.2 37%
Product
Aur1H
Gene
aur1H
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
8
 CYPK_STRCO
(Q02055)		 Jump to Actino_00210 
[query] 4 - 157 (169)
[subject] 9 - 148 (316)
 1e-17 93.2 40%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
ACTVII
actI ORF4
Gene
SCO5090
SCBAC28G1.16
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1527048 [Medline] 92406871
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
9
 D7RFJ9_AMYOR
(D7RFJ9)		 
[query] 1 - 119 (169)
[subject] 1 - 117 (309)
 1e-17 92.8 42%
Product
Putative cyclase
Gene
bexL
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
11
 Q93M00_STRAU
(Q93M00)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (316)
 1e-17 92.8 37%
Product
Cyclase/dehydratase-like protein
Gene
aur2F
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 15497441
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004]
12
 Q2HR24_9ACTO
(Q2HR24)		 Jump to Sch475_00340 
[query] 1 - 156 (169)
[subject] 3 - 147 (312)
 7e-17 90.9 38%
Product
Putative aromatase
Gene
schP4
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
13
 D9UBK6_STRPR
(D9UBK6)		 
[query] 6 - 156 (169)
[subject] 11 - 150 (318)
(2 hsp)		 9e-17 90.1 39%
Product
Putative cyclase
Gene
c104_07c
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
15
 Q93LY0_9ACTO
(Q93LY0)		 
[query] 1 - 150 (169)
[subject] 6 - 144 (314)
 1e-16 90.1 39%
Product
Putative bifunctional aromatase PgaL
Gene
pgaL
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
16
 Q4R0M7_STRCX
(Q4R0M7)		 Jump to Chart_00050 
[query] 1 - 111 (169)
[subject] 6 - 116 (322)
 1e-16 89.7 41%
Product
ChaF protein
Gene
chaF
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
18
 Q2J5J6_FRASC
(Q2J5J6)		 
[query] 6 - 155 (169)
[subject] 9 - 147 (319)
 1e-16 89.7 38%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Francci3_4098
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
19
 Q2J5F1_FRASC
(Q2J5F1)		 
[query] 2 - 155 (169)
[subject] 10 - 152 (318)
 1e-16 89.7 38%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Francci3_4143
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
21
 Q54490_STRNO
(Q54490)		 Jump to Nogl_00320 
[query] 4 - 150 (169)
[subject] 13 - 148 (323)
 3e-16 89   36%
Product
SnoaE
Gene
snoaE
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
22
 Q9RPB1_STRFR
(Q9RPB1)		 Jump to Urd_00160 
[query] 2 - 155 (169)
[subject] 4 - 146 (311)
 3e-16 88.6 36%
Product
Cyclase
Gene
urdL
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
26
 Q54221_STRGR
(Q54221)		 Jump to Griseu_00050 
[query] 1 - 156 (169)
[subject] 6 - 150 (319)
 1e-15 87   36%
Product
Putative cyclase/dehydrase
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
27
 Q54999_9ACTO
(Q54999)		 Jump to Fren_00170 
[query] 4 - 164 (169)
[subject] 14 - 161 (331)
 2e-15 86.3 35%
Product
Aromatase
Gene
frnQ
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
28
 CYPK_STRVN
(P16560)		 Jump to Grana_00290 
[query] 5 - 155 (169)
[subject] 20 - 159 (324)
 2e-15 85.9 37%
Product
Granaticin polyketide synthase bifunctional cyclase/dehydratase
Gene
gra-orf4
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
29
 D7BZR8_STRBB
(D7BZR8)		 
[query] 6 - 155 (169)
[subject] 11 - 149 (324)
 2e-15 85.9 38%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
SBI_06853
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
30
 C4NYK3_9ACTO
(C4NYK3)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (314)
 3e-15 85.1 34%
Product
SaqL
Gene
saqL
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
33
 Q6VMJ1_STRAM
(Q6VMJ1)		 
[query] 2 - 150 (169)
[subject] 4 - 141 (314)
 9e-15 83.6 38%
Product
Putative bifunctional cyclase/dehydrase
Putative cyclase/dehydratase
Gene
alpE
DSMT0181
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
34
 Q1RQS4_STRAM
(Q1RQS4)		 
[query] 2 - 150 (169)
[subject] 4 - 141 (314)
 9e-15 83.6 38%
Product
Putative cyclase/dehydratase
Gene
alpE
SAMT0161
SAMT0162
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
37
 C7PWQ8_CATAD
(C7PWQ8)		 
[query] 6 - 148 (169)
[subject] 20 - 156 (330)
 1e-14 83.2 33%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Caci_6488
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
38
 D6MSV2_9ACTO
(D6MSV2)		 
[query] 2 - 159 (169)
[subject] 7 - 153 (314)
 1e-14 83.2 37%
Product
SsfY1
Gene
ssfY1
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
39
 D5MRI9_9ACTO
(D5MRI9)		 
[query] 2 - 156 (169)
[subject] 4 - 147 (311)
 1e-14 83.2 37%
Product
Putative aromatase
Gene
hrbP
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
40
 Q7WT27_9ACTO
(Q7WT27)		 Jump to Medem_00150 
[query] 2 - 156 (169)
[subject] 7 - 150 (318)
 3e-14 81.6 35%
Product
First ring aromatase (ARO)
Gene
med-ORF19
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
42
 Q55220_STRSQ
(Q55220)		 Jump to Dauno_00130 
[query] 1 - 150 (169)
[subject] 6 - 144 (315)
 4e-14 81.6 36%
Product
Cyclase/dehydrase
Gene
dauA
Organism
Streptomyces sp
1uniprot[Pubmed] 7928998 [Medline] 95014072
Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.(J. Bacteriol.) [1994]
43
 D2XDY3_9PSEU
(D2XDY3)		 
[query] 1 - 156 (169)
[subject] 6 - 150 (316)
 4e-14 81.3 35%
Product
AzicE
Gene
azicE
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
44
 Q9FCM5_STRAT
(Q9FCM5)		 
[query] 1 - 155 (169)
[subject] 6 - 149 (318)
 5e-14 81.3 35%
Product
Putative aromatase
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11700358 [Medline] 21557167
A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001]
48
 Q9AMI9_STRAT
(Q9AMI9)		 
[query] 1 - 161 (169)
[subject] 6 - 155 (315)
 1e-13 79.7 36%
Product
Putative cyclase/dehydrase SimA5
Sim6
Gene
simA5
sim6
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
50
 Q9X464_STRAE
(Q9X464)		 Jump to Naphcy_00040 
[query] 3 - 150 (169)
[subject] 9 - 145 (315)
 2e-13 79   34%
Product
Aromatase
Gene
ncnD
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]
51
 Q54811_STRPE
(Q54811)		 Jump to Adria_00240 
[query] 1 - 156 (169)
[subject] 6 - 150 (315)
 2e-13 79   35%
Product
Daunorubicin-doxorubicin polyketide synthase
Gene
dpsF
Organism
Streptomyces peucetius
1uniprot[Pubmed] 7828855 [Medline] 95129838
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994]
53
 B3VNY8_9ACTO
(B3VNY8)		 
[query] 30 - 155 (169)
[subject] 1 - 115 (214)
 8e-13 77.4 39%
Product
Putative cyclase/dehydratase
Gene
 
Organism
Micromonospora sp. 8g107
1uniprot[Pubmed] 21287404
A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011]
57
 F2RC19_STRVP
(F2RC19)		 
[query] 2 - 155 (169)
[subject] 4 - 146 (311)
 2e-12 76.3 35%
Product
Bifunctional cyclase or dehydrase
Gene
SVEN_5984
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
59
 CYPK_STRCM
(P41178)		 
[query] 2 - 110 (169)
[subject] 4 - 112 (304)
 9e-12 73.6 39%
Product
Granaticin polyketide synthase bifunctional cyclase/dehydratase
ORF4
Gene
 
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 1508151 [Medline] 92374994
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992]
61
 Q9ZGD3_STRCY
(Q9ZGD3)		 Jump to Lando_00070 
[query] 1 - 155 (169)
[subject] 3 - 153 (319)
 6e-11 71.2 35%
Product
Cyclase homolog
Gene
lanL
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
62
 Q7X2H2_9ACTO
(Q7X2H2)		 Jump to Gilvo_00220 
[query] 6 - 168 (169)
[subject] 10 - 161 (316)
 1e-10 70.1 30%
Product
Putative cyclase/dehydratase
Gene
gilK
Organism
Streptomyces griseoflavus
1uniprot[Pubmed] 12822997 [Medline] 22708304
The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003]
64
 Q8VWB6_9ACTO
(Q8VWB6)		 
[query] 4 - 111 (169)
[subject] 8 - 115 (450)
 6e-10 67.8 36%
Product
AknE1
Gene
aknE1
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
65
 Q3S8Q5_STRRM
(Q3S8Q5)		 Jump to Oxtet_00110 
[query] 6 - 155 (169)
[subject] 11 - 149 (317)
 6e-10 67.8 33%
Product
OxyK
Gene
oxyK
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
66
 Q56167_9ACTO
(Q56167)		 Jump to Jado_00120 
[query] 2 - 155 (169)
[subject] 4 - 145 (310)
 7e-10 67.4 34%
Product
Bifunctional cyclase/dehydrase
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
67
 Q9ZG83_STRRM
(Q9ZG83)		 
[query] 6 - 155 (169)
[subject] 11 - 149 (297)
 7e-10 67.4 33%
Product
Cyclase/aromatase
Gene
otcD1
Organism
Streptomyces rimosus
1uniprot[Pubmed] 10551844 [Medline] 20020252
Disruption of an aromatase/cyclase from the oxytetracycline gene cluster of Streptomyces rimosus results in production of novel polyketides with shorter chain lengths.(J. Biol. Chem.) [1999]
2uniprot
Characterisation of some genes involved in the early steps of the biosynthetic pathway for oxytetracycline in Streptomyces rimosus. [1994]
69
 Q9L554_9ACTO
(Q9L554)		 Jump to Acla_00040 
[query] 4 - 111 (169)
[subject] 8 - 115 (450)
 1e-09 66.6 36%
Product
AknE1
Gene
aknE1
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
73
 D1A6S1_THECD
(D1A6S1)		 
[query] 1 - 156 (169)
[subject] 25 - 169 (340)
 6e-09 64.3 30%
Product
Cyclase/dehydrase
Gene
Tcur_2780
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
77
 Q93HL9_STRAW
(Q93HL9)		 
[query] 3 - 159 (169)
[subject] 4 - 149 (159)
 1e-08 63.2 26%
Product
Cyclase I
Putative cyclase I
Gene
sppD
SAV2841
SAV_2841
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
80
 Q83X42_STRRO
(Q83X42)		 
[query] 6 - 159 (169)
[subject] 14 - 156 (321)
 2e-08 62.4 32%
Product
Cyclase/aromatase
Gene
rocH
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
82
 Q8KSW2_9ACTO
(Q8KSW2)		 Jump to Griseo_00300 
[query] 3 - 111 (169)
[subject] 4 - 112 (402)
 3e-08 62   34%
Product
Putative bifunctional cyclase/3-oxoacyl-ACP reductase GrhT
Gene
grhT
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
83
 Q2J931_FRASC
(Q2J931)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (162)
 3e-08 62   32%
Product
Cyclase/dehydrase
Gene
Francci3_2853
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
84
 F2RIV3_STRVP
(F2RIV3)		 
[query] 3 - 93 (169)
[subject] 4 - 95 (159)
 5e-08 61.2 32%
Product
Aromatase WhiE VI
Gene
SVEN_6793
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
85
 A2AXE4_STRCM
(A2AXE4)		 
[query] 6 - 138 (169)
[subject] 12 - 145 (373)
 7e-08 60.8 29%
Product
Putative polyketide cyclase/aromatase
Gene
fnq5
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
86
 F4F9S5_VERMA
(F4F9S5)		 
[query] 3 - 114 (169)
[subject] 86 - 197 (244)
 7e-08 60.8 33%
Product
Cyclase/dehydrase
Gene
VAB18032_23765
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
88
 E2PW01_STRCL
(E2PW01)		 
[query] 3 - 93 (169)
[subject] 4 - 95 (161)
 1e-07 60.1 37%
Product
Polyketide cyclase
Gene
sppD
SCLAV_4918
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
90
 CYPC_STRCO
(P23154)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (159)
 2e-07 59.7 29%
Product
Putative polyketide cyclase
WhiE ORF VI
Gene
SCO5315
SC6G9.18
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 2077356 [Medline] 91171868
Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics.(Mol. Microbiol.) [1990]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
92
 Q0RHJ5_FRAAA
(Q0RHJ5)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (164)
 3e-07 58.5 29%
Product
Putative polyketide cyclase
Gene
FRAAL4389
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
94
 A7DWI6_STRTE
(A7DWI6)		 
[query] 3 - 141 (169)
[subject] 4 - 143 (155)
 4e-07 58.2 29%
Product
Putative polyketide cyclase
Gene
llpCI
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
95
 D7C2K5_STRBB
(D7C2K5)		 
[query] 3 - 161 (169)
[subject] 4 - 151 (154)
 4e-07 58.2 28%
Product
Putative polyketide cyclase I
Gene
sppD
SBI_02767
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
96
 B3VNY6_9ACTO
(B3VNY6)		 
[query] 30 - 150 (169)
[subject] 1 - 110 (213)
 4e-07 58.2 35%
Product
Putative cyclase/dehydratase
Gene
 
Organism
Streptomyces sp. 15MN1
1uniprot[Pubmed] 21287404
A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011]
97
 B7TX46_9ACTO
(B7TX46)		 
[query] 30 - 155 (169)
[subject] 1 - 115 (214)
 4e-07 58.2 33%
Product
Putative cyclase/dehydratase
Gene
 
Organism
Streptomyces sp. 6G13
1uniprot[Pubmed] 21287404
A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.(Antonie Van Leeuwenhoek) [2011]
98
 B6SEF5_9ACTO
(B6SEF5)		 Jump to Alnu_00100 
[query] 2 - 156 (169)
[subject] 15 - 158 (331)
 6e-07 57.8 31%
Product
AlnQ aromatase
Gene
alnQ
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
99
 D2AY47_STRRD
(D2AY47)		 
[query] 3 - 134 (169)
[subject] 4 - 137 (160)
 6e-07 57.8 29%
Product
Putative uncharacterized protein
Gene
Sros_4153
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]