Function : Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)

Function Description

ID	NFUNC_0043
Created	2013-03-06
Description	Resistance to aminoglycoside antibiotics by phosphorylation of aminoglycoside catalyzed by aminoglycoside O-phosphotransferase.
Comment	Not assigned
Cross Reference	PMID 20833577 Wikipedia Streptomycin 6-kinase Wikipedia Aminoglycoside Wikipedia Kanamycin kinase

Function Constitution


Type	Pattern	Component Gene
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043)
Require	A	APH6 (NRULE_0155)	Streptomycin 6-kinase
	B	APH3 (NRULE_0156)	Aminoglycoside 3'-phosphotransferase
	C	APH7 (NRULE_0157)	Hygromycin-B 7''-O-kinase
	D	HPH (NRULE_0174)	Hygromycin-B 4-O-kinase

Potential Functional Microbe

Scientific name	NBRC No.	Scientific name	NBRC No.	Scientific name	NBRC No.
Acaricomes phytoseiuli	107788	Acidithiobacillus ferrooxidans		Actinoalloteichus cyanogriseus	14455
Actinoalloteichus spitiensis	102582	Actinopolyspora iraqiensis	103187	Actinosynnema mirum	14064
Alloiococcus otitis	15545	Amycolatopsis azurea	14573	Amycolatopsis mediterranei	13415
Anoxybacillus flavithermus	15317	Arcanobacterium haemolyticum	15585	Arthrobacter globiformis	12137
Bacillus atrophaeus	13721	Bacillus cereus	15305	Bacillus licheniformis	12200
Bacillus licheniformis	12195	Bacillus mycoides	101228	Bacillus pseudomycoides	101232
Bacillus psychrosaccharolyticus	101233	Bacillus thuringiensis	101235	Beutenbergia cavernae	16432
Bradyrhizobium diazoefficiens	14792	Brevibacillus brevis	100599	Brevibacterium linens	12170
Brevundimonas diminuta	12697	Catenulispora acidiphila	102108	Cellulomonas flavigena	3775
Chthoniobacter flavus		Conexibacter woesei	100937	Coprobacillus sp.
Cystobacter fuscus	100088	Deinococcus proteolyticus	101906	Enterococcus gilvus	100696
Escherichia fergusonii	102419	Fimbriimonas ginsengisoli		Gordonia alkanivorans	16433
Gordonia amicalis	100051	Gordonia araii	100433	Gordonia bronchialis	16047
Gordonia effusa	100432	Gordonia hirsuta	16056	Gordonia namibiensis	108229
Gordonia rubripertincta	101908	Gordonia soli	108243	Gordonia terrae	100016
Halobacillus halophilus	102448	Intrasporangium calvum	12989	Kineococcus radiotolerans	101839
Kineosphaera limosa	100340	Kitasatospora setae	14216	Kocuria rhizophila	103217
Kribbella flavida	14399	Ktedonobacter racemifer		Labrenzia aggregata	16684
Lactobacillus helveticus	15019	Lactobacillus reuteri	15892	Magnetospirillum magnetotacticum	15272
Meiothermus silvanus	106475	Microlunatus phosphovorus	101784	Micromonospora aurantiaca	16155
Mobilicoccus pelagius	104925	Nocardiopsis dassonvillei	14626	Ochrobactrum anthropi	15819
Ochrobactrum intermedium	15820	Oscillibacter valericigenes	101213	Paenibacillus alvei	3343
Paenibacillus polymyxa	15309	Renibacterium salmoninarum	15589	Rhizobium etli	15573
Rhizobium tropici	15247	Rhodobacter capsulatus	16581	Rubrobacter xylanophilus	100952
Saccharomonospora azurea	14651	Saccharomonospora cyanea	14841	Saccharomonospora glauca	14831
Saccharopolyspora erythraea	13426	Saccharopolyspora spinosa	15153	Saccharothrix espanaensis	15066
Salinispora tropica	105044	Sanguibacter keddieii	16158	Serratia odorifera	102598
Sphingobium japonicum	101211	Sphingomonas wittichii	105917	Sporichthya polymorpha	12702
Stackebrandtia nassauensis	102104	Streptomyces avermitilis	14893	Streptomyces cattleya	14057
Streptomyces clavuligerus	13307	Streptomyces ghanaensis	15414	Streptomyces mobaraensis	13819
Streptomyces pristinaespiralis	13074	Streptomyces purpureus	13925	Streptomyces sviceus	13980
Streptomyces venezuelae	13096	Streptosporangium roseum	3776	Tetragenococcus halophilus	12172
Thermobispora bispora	14880	Thermus thermophilus	101085	Thermus thermophilus	101084
Tsukamurella paurometabola	16120	Vibrio tubiashii	15644	Xylanimonas cellulosilytica	107835
Yersinia bercovieri	105717