BLAST table : Fren_00070

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
O68913_9ACTO
(O68913)
[query] 1 - 282 (282)
[subject] 1 - 282 (282)
1e-159 563   100% Pathway specific regulator frnG Streptomyces roseofulvus
2
D9UKN0_9ACTO
(D9UKN0)
[query] 1 - 282 (282)
[subject] 1 - 282 (282)
1e-157 558   99% Pathway specific regulator SSLG_05746 Streptomyces sp. SPB78
3
B5UAT2_STRLA
(B5UAT2)
[query] 1 - 255 (282)
[subject] 1 - 255 (273)
7e-54 215   49% SARP family regulator farR4 Streptomyces lavendulae
4
D9W572_9ACTO
(D9W572)
[query] 1 - 255 (282)
[subject] 1 - 255 (274)
4e-53 213   48% SARP family regulator SSNG_07302 Streptomyces sp. C
5
D7CHH7_STRBB
(D7CHH7)
[query] 1 - 263 (282)
[subject] 1 - 267 (271)
7e-52 208   47% SARP family pathway specific regulatory protein SBI_03913 Streptomyces bingchenggensis (strain BCW-1)
6
E1ARL5_STRAU
(E1ARL5)
[query] 1 - 255 (282)
[subject] 1 - 259 (292)
8e-52 208   49% Putative SARP family pathway specific regulatory protein sa37 Streptomyces aureofaciens
7
E1ARN0_STRAU
(E1ARN0)
[query] 1 - 258 (282)
[subject] 1 - 258 (272)
2e-51 207   49% SARP family pathway specific regulatory protein sa24 Streptomyces aureofaciens
8
E0KYL3_STRVO
(E0KYL3)
[query] 1 - 263 (282)
[subject] 1 - 267 (271)
3e-51 206   47% Transcriptional regulator, SARP family StrviDRAFT_7741 Streptomyces violaceusniger Tu 4113
9
Q83X49_STRRO
(Q83X49)
[query] 1 - 261 (282)
[subject] 1 - 263 (289)
1e-50 204   48% SARP family regulator SrrW srrW Streptomyces rochei
Streptomyces parvullus
10
Q9KHL3_9ACTO
(Q9KHL3)
Jump to Enter_00020
[query] 1 - 255 (282)
[subject] 1 - 251 (283)
3e-50 203   46% Putative transcriptional regulator EncF encF Streptomyces maritimus
11
Q9XCC4_STRFR
(Q9XCC4)
[query] 1 - 257 (282)
[subject] 1 - 260 (277)
3e-50 203   48% Hypothetical pathway specific regulatory protein TylS tylS Streptomyces fradiae
Streptomyces roseoflavus
12
D9WG83_9ACTO
(D9WG83)
[query] 1 - 263 (282)
[subject] 1 - 267 (271)
4e-50 202   47% Regulatory protein DnrI SSOG_03013 Streptomyces himastatinicus ATCC 53653
13
D6AAR9_9ACTO
(D6AAR9)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
5e-50 202   44% Putative uncharacterized protein SSFG_07839 Streptomyces ghanaensis ATCC 14672
14
Q9L4V0_9ACTO
(Q9L4V0)
Jump to Acla_00170
[query] 1 - 265 (282)
[subject] 1 - 264 (272)
1e-49 201   45% Putative activator aknO Streptomyces galilaeus
15
B5HIW5_STRPR
(B5HIW5)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
1e-49 201   45% Transcriptional activator domain-containing protein SSDG_05102 Streptomyces pristinaespiralis ATCC 25486
16
A2AXE3_STRCM
(A2AXE3)
[query] 1 - 255 (282)
[subject] 41 - 294 (313)
1e-49 201   44% Putative SARP family pathway-specific regulator fnq4 Streptomyces cinnamonensis
17
E8RWU1_MICSL
(E8RWU1)
[query] 1 - 267 (282)
[subject] 1 - 268 (651)
3e-49 199   45% Transcriptional regulator, SARP family ML5_4430 Micromonospora sp. (strain L5)
18
D9T288_MICAI
(D9T288)
[query] 1 - 267 (282)
[subject] 1 - 268 (651)
3e-49 199   45% Transcriptional activator domain Micau_3991 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
19
Q8KSZ0_9ACTO
(Q8KSZ0)
Jump to Griseo_00020
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
5e-49 199   45% Putative transcriptional activator GrhR2 grhR2 Streptomyces sp. JP95
20
Q0JW85_STRAM
(Q0JW85)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
9e-49 198   48% Putative SARP family pathway specific regulatory protein DSMT0201 Streptomyces ambofaciens
21
Q6VMH3_STRAM
(Q6VMH3)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
1e-48 197   48% Putative SARP family pathway specific regulatory protein alpV Streptomyces ambofaciens
22
Q1RQQ4_STRAM
(Q1RQQ4)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
1e-48 197   48% Putative SARP family pathway specific regulatory protein alpV
SAMT0181
SAMT0182
Streptomyces ambofaciens ATCC 23877
23
B5G8A6_9ACTO
(B5G8A6)
[query] 1 - 266 (282)
[subject] 48 - 312 (319)
5e-48 196   44% Transcriptional regulatory protein, C SSBG_00514 Streptomyces sp. SPB74
24
D9UBW9_STRPR
(D9UBW9)
[query] 1 - 257 (282)
[subject] 1 - 284 (300)
7e-48 195   44% SARP-type regulator papR4 Streptomyces pristinaespiralis
25
Q2L6C8_9ACTO
(Q2L6C8)
[query] 1 - 255 (282)
[subject] 71 - 324 (343)
8e-48 195   44% Putative transcriptional regulator Streptomyces sp. KO-3988
26
Q2PA02_9ACTO
(Q2PA02)
Jump to Stref_00130
[query] 1 - 259 (282)
[subject] 1 - 258 (290)
9e-48 194   46% SARP family regulator stfRI Streptomyces steffisburgensis
27
Q83X33_STRRO
(Q83X33)
[query] 1 - 259 (282)
[subject] 1 - 262 (273)
2e-47 194   43% SARP family regulator SrrZ srrZ Streptomyces rochei
Streptomyces parvullus
28
D6AAS1_9ACTO
(D6AAS1)
[query] 1 - 264 (282)
[subject] 1 - 283 (290)
2e-47 194   44% SARP family pathway specific regulatory protein SSFG_07841 Streptomyces ghanaensis ATCC 14672
29
D9UBT4_STRPR
(D9UBT4)
[query] 19 - 255 (282)
[subject] 4 - 239 (258)
3e-47 193   46% SARP-type regulator cpp1 Streptomyces pristinaespiralis
30
D9UBV4_STRPR
(D9UBV4)
[query] 1 - 255 (282)
[subject] 1 - 255 (285)
2e-46 191   47% SARP-type regulator papR1 Streptomyces pristinaespiralis
31
D6X7H8_STRPR
(D6X7H8)
[query] 1 - 255 (282)
[subject] 1 - 255 (285)
2e-46 191   47% SARP family regulator SSDG_07486 Streptomyces pristinaespiralis ATCC 25486
32
DNRI_STRPE
(P25047)
Jump to Adria_00210
[query] 1 - 275 (282)
[subject] 1 - 272 (272)
2e-46 191   44% Regulatory protein dnrI dnrI Streptomyces peucetius
33
D7BZQ7_STRBB
(D7BZQ7)
[query] 1 - 255 (282)
[subject] 1 - 254 (274)
2e-46 190   48% SARP family pathway specific regulatory protein SBI_06842 Streptomyces bingchenggensis (strain BCW-1)
34
Q6VMH5_STRAM
(Q6VMH5)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
2e-46 190   44% Putative SARP family pathway specific regulatory protein alpT Streptomyces ambofaciens
35
Q1RQQ6_STRAM
(Q1RQQ6)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
2e-46 190   44% Putative SARP family pathway specific regulatory protein alpT
SAMT0179
SAMT0180
Streptomyces ambofaciens ATCC 23877
36
D1A6U2_THECD
(D1A6U2)
[query] 1 - 269 (282)
[subject] 2 - 266 (267)
3e-46 189   43% Transcriptional regulator, SARP family Tcur_2801 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
37
Q0JW87_STRAM
(Q0JW87)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
8e-46 188   44% Putative SARP family pathway specific regulatory protein DSMT0199 Streptomyces ambofaciens
38
E2Q9D3_STRCL
(E2Q9D3)
[query] 1 - 264 (282)
[subject] 1 - 265 (278)
8e-46 188   44% SARP family pathway specific regulatory protein SCLAV_0477 Streptomyces clavuligerus ATCC 27064
39
Q9KWX4_STRAM
(Q9KWX4)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
8e-46 188   44% Regulator (SAR) sar Streptomyces ambofaciens
40
C9ZCD2_STRSW
(C9ZCD2)
[query] 1 - 267 (282)
[subject] 1 - 268 (278)
1e-45 187   43% Putative regulatory protein SCAB_63171 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
41
D9W573_9ACTO
(D9W573)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
1e-45 187   44% SARP family regulator SSNG_07303 Streptomyces sp. C
42
D9WNL0_9ACTO
(D9WNL0)
[query] 1 - 255 (282)
[subject] 1 - 254 (274)
2e-45 187   48% Regulatory protein DnrI SSOG_05581 Streptomyces himastatinicus ATCC 53653
43
E8W955_STRFA
(E8W955)
[query] 1 - 272 (282)
[subject] 4 - 268 (268)
2e-45 187   44% Transcriptional regulator, SARP family Sfla_5321 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
44
B0LIZ8_9ACTO
(B0LIZ8)
[query] 1 - 251 (282)
[subject] 1 - 253 (276)
3e-45 186   44% Lct15 lct15 Streptomyces rishiriensis
45
E0KZW2_STRVO
(E0KZW2)
[query] 1 - 255 (282)
[subject] 1 - 254 (274)
3e-45 186   47% Transcriptional regulator, SARP family StrviDRAFT_8190 Streptomyces violaceusniger Tu 4113
46
A7DWL6_STRTE
(A7DWL6)
[query] 1 - 263 (282)
[subject] 1 - 266 (613)
4e-45 186   43% Putative transcriptional activator, SARP family llpRIV Streptomyces tendae
47
E1ARL7_STRAU
(E1ARL7)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
4e-45 186   43% Putative SARP family pathway specific regulatory protein sa35 Streptomyces aureofaciens
48
B5UAT1_STRLA
(B5UAT1)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
4e-45 186   44% SARP family regulator farR3 Streptomyces lavendulae
49
Q54494_STRNO
(Q54494)
Jump to Nogl_00360
[query] 1 - 259 (282)
[subject] 28 - 277 (665)
5e-45 185   43% Snora snorA Streptomyces nogalater
50
Q83X29_STRRO
(Q83X29)
[query] 1 - 257 (282)
[subject] 1 - 260 (276)
7e-45 185   44% SARP family regulator SrrY srrY Streptomyces rochei
Streptomyces parvullus
51
E2EKL8_9ACTO
(E2EKL8)
[query] 1 - 272 (282)
[subject] 2 - 274 (610)
9e-45 185   43% Regulator sanR1 Streptomyces sp. SANK 61196
52
Q70J84_STRGR
(Q70J84)
Jump to Chro_00140
[query] 1 - 255 (282)
[subject] 10 - 266 (300)
1e-44 184   43% Transcriptional regulator cmmRI Streptomyces griseus subsp. griseus
53
Q4R0M3_STRCX
(Q4R0M3)
Jump to Chart_00090
[query] 46 - 255 (282)
[subject] 1 - 209 (216)
1e-44 184   46% ChaR1 protein chaR1 Streptomyces chartreusis
54
C6FX55_STRAS
(C6FX55)
[query] 1 - 254 (282)
[subject] 53 - 308 (323)
6e-44 182   43% NosP nosP Streptomyces actuosus
55
E5DUG1_9NOCA
(E5DUG1)
[query] 1 - 257 (282)
[subject] 2 - 260 (299)
1e-43 181   43% NocP nocP Nocardia sp. ATCC 202099
56
E4NBI0_KITSK
(E4NBI0)
[query] 1 - 263 (282)
[subject] 1 - 260 (269)
2e-43 180   43% Putative AfsR family transcriptional regulator KSE_27490 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
57
D2AY68_STRRD
(D2AY68)
[query] 1 - 260 (282)
[subject] 1 - 258 (621)
3e-43 179   42% Transcriptional regulator, SARP family Sros_4174 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
58
Q8KSZ1_9ACTO
(Q8KSZ1)
Jump to Griseo_00010
[query] 1 - 251 (282)
[subject] 1 - 254 (273)
4e-43 179   45% Putative transcriptional activator GrhR1 grhR1 Streptomyces sp. JP95
59
B5G879_9ACTO
(B5G879)
[query] 1 - 254 (282)
[subject] 2 - 254 (281)
5e-43 179   43% Transcriptional regulatory protein, C SSBG_00487 Streptomyces sp. SPB74
60
Q8VWA7_9ACTO
(Q8VWA7)
[query] 1 - 254 (282)
[subject] 1 - 253 (280)
5e-43 179   44% AclI aclI Streptomyces galilaeus
61
D8I4K7_AMYMU
(D8I4K7)
[query] 1 - 255 (282)
[subject] 1 - 249 (617)
5e-43 179   42% SARP family transcriptional regulator AMED_5421 Amycolatopsis mediterranei (strain U-32)
62
Q9L545_9ACTO
(Q9L545)
Jump to Acla_00140
[query] 1 - 254 (282)
[subject] 1 - 253 (280)
6e-43 179   44% AknI aknI Streptomyces galilaeus
63
Q9LBV5_STRVG
(Q9LBV5)
Jump to Virg_00290
[query] 1 - 255 (282)
[subject] 1 - 255 (271)
1e-42 177   46% Orf2 Streptomyces virginiae
64
D6AXN0_9ACTO
(D6AXN0)
[query] 2 - 255 (282)
[subject] 15 - 268 (286)
3e-42 176   40% Putative uncharacterized protein SSHG_05322 Streptomyces albus J1074
65
D2SZ12_MICEC
(D2SZ12)
[query] 1 - 265 (282)
[subject] 1 - 272 (293)
3e-42 176   42% Transcriptional regulator Micromonospora echinospora subsp. challisensis
66
C7PY63_CATAD
(C7PY63)
[query] 1 - 252 (282)
[subject] 1 - 251 (252)
8e-42 175   42% Transcriptional regulator, SARP family Caci_6503 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
67
D9W8G2_9ACTO
(D9W8G2)
[query] 1 - 254 (282)
[subject] 1 - 253 (260)
9e-42 175   41% Regulatory protein DnrI SSOG_02383 Streptomyces himastatinicus ATCC 53653
68
C9ZCB7_STRSW
(C9ZCB7)
[query] 1 - 255 (282)
[subject] 1 - 246 (919)
1e-41 174   44% Putative transcriptional activator SCAB_63021 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
69
B6SEG7_9ACTO
(B6SEG7)
Jump to Alnu_00220
[query] 1 - 253 (282)
[subject] 1 - 252 (271)
2e-41 174   43% AlnR3 SARP family regulator alnR3 Streptomyces sp. CM020
70
D7CH46_STRBB
(D7CH46)
[query] 1 - 255 (282)
[subject] 1 - 249 (617)
4e-41 172   42% Transcriptional regulator, SARP family protein SBI_01760 Streptomyces bingchenggensis (strain BCW-1)
71
D6AEP3_STRFL
(D6AEP3)
[query] 1 - 255 (282)
[subject] 1 - 250 (262)
4e-41 172   41% Tylosin biosynthesis-specific regulatory protein tylS SSGG_02135 Streptomyces roseosporus NRRL 15998
72
E3T487_9ACTO
(E3T487)
[query] 3 - 255 (282)
[subject] 1 - 259 (278)
1e-40 171   44% Pathway-specific transcriptional activator gra-orf9 Streptomyces vietnamensis
73
C7N0E0_SACVD
(C7N0E0)
[query] 1 - 254 (282)
[subject] 1 - 250 (631)
1e-40 171   43% DNA-binding transcriptional activator of the SARP family Svir_33780 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
74
Q8KY34_STRCU
(Q8KY34)
[query] 1 - 252 (282)
[subject] 16 - 274 (661)
2e-40 170   42% RubS rubS Streptomyces collinus
75
D9W557_9ACTO
(D9W557)
[query] 14 - 255 (282)
[subject] 15 - 255 (274)
2e-40 170   44% SARP family regulator SSNG_07287 Streptomyces sp. C
76
Q67G41_9ACTO
(Q67G41)
Jump to Heda_00170
[query] 1 - 259 (282)
[subject] 1 - 266 (272)
2e-40 170   43% Putative regulatory protein Streptomyces griseoruber
77
Q7WT17_9ACTO
(Q7WT17)
Jump to Medem_00250
[query] 1 - 252 (282)
[subject] 1 - 249 (258)
3e-40 170   42% Pathway-specific transcriptional activator (SARP) med-ORF11 Streptomyces sp. AM-7161
78
D9W5M6_9ACTO
(D9W5M6)
[query] 1 - 254 (282)
[subject] 1 - 252 (1010)
6e-40 169   42% Predicted protein SSNG_07456 Streptomyces sp. C
79
D9WWT9_9ACTO
(D9WWT9)
[query] 1 - 254 (282)
[subject] 1 - 247 (256)
1e-39 168   41% Activator protein SSOG_08429 Streptomyces himastatinicus ATCC 53653
80
C0JWC2_9ACTO
(C0JWC2)
Jump to Polk_00270
[query] 1 - 256 (282)
[subject] 1 - 254 (270)
2e-39 167   42% PokR2 pokR2 Streptomyces diastatochromogenes
81
E2Q9B8_STRCL
(E2Q9B8)
[query] 1 - 276 (282)
[subject] 1 - 273 (931)
3e-38 163   40% Putative regulatory protein AfsR-like protein SCLAV_0462 Streptomyces clavuligerus ATCC 27064
82
E5RLL0_9ACTO
(E5RLL0)
[query] 1 - 255 (282)
[subject] 1 - 250 (635)
3e-38 163   43% Putative transcriptional regulator pnxR2 Streptomyces sp. TA-0256
83
C7QAG9_CATAD
(C7QAG9)
[query] 14 - 254 (282)
[subject] 13 - 249 (261)
4e-38 163   42% Transcriptional regulator, SARP family Caci_3563 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
84
E3JBV0_FRASU
(E3JBV0)
[query] 1 - 258 (282)
[subject] 22 - 272 (282)
6e-38 162   39% Transcriptional regulator, SARP family FraEuI1c_4261 Frankia sp. (strain EuI1c)
85
E0KYD3_STRVO
(E0KYD3)
[query] 1 - 251 (282)
[subject] 1 - 250 (276)
9e-38 161   42% Transcriptional regulator, SARP family StrviDRAFT_7661 Streptomyces violaceusniger Tu 4113
86
F4FBT2_VERMA
(F4FBT2)
[query] 1 - 256 (282)
[subject] 2 - 250 (260)
1e-37 161   41% SARP family transcriptional regulator VAB18032_18150 Verrucosispora maris (strain AB-18-032)
87
Q194R8_STRAA
(Q194R8)
Jump to Mith_00020
[query] 3 - 252 (282)
[subject] 1 - 248 (276)
1e-37 161   40% Mithramycin regulator MtmR mtmR Streptomyces argillaceus
88
Q9ZA48_STRVN
(Q9ZA48)
Jump to Grana_00030
[query] 1 - 266 (282)
[subject] 1 - 278 (283)
4e-37 159   41% Pathway-specific transcriptional activator gra-orf9 Streptomyces violaceoruber
89
D9WMS0_9ACTO
(D9WMS0)
[query] 3 - 258 (282)
[subject] 23 - 278 (279)
4e-37 159   38% Regulatory protein DnrI SSOG_07650 Streptomyces himastatinicus ATCC 53653
90
E1ARN1_STRAU
(E1ARN1)
[query] 1 - 255 (282)
[subject] 1 - 249 (268)
6e-37 159   39% Putative SARP family pathway specific regulatory protein sa23 Streptomyces aureofaciens
91
E3J3Q3_FRASU
(E3J3Q3)
[query] 3 - 251 (282)
[subject] 75 - 319 (322)
6e-37 159   40% Transcriptional regulator, SARP family FraEuI1c_1323 Frankia sp. (strain EuI1c)
92
E0KNB9_STRVO
(E0KNB9)
[query] 14 - 254 (282)
[subject] 17 - 251 (260)
9e-37 158   41% Transcriptional regulator, SARP family StrviDRAFT_4146 Streptomyces violaceusniger Tu 4113
93
D9XDJ2_STRVR
(D9XDJ2)
[query] 1 - 259 (282)
[subject] 1 - 259 (287)
1e-36 157   39% SARP family pathway specific regulatory protein SSQG_00889 Streptomyces viridochromogenes DSM 40736
94
D2AQB1_STRRD
(D2AQB1)
[query] 1 - 254 (282)
[subject] 1 - 242 (950)
2e-36 157   42% Transcriptional regulator, SARP family Sros_1461 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
95
Q1MX65_9ACTO
(Q1MX65)
Jump to Tetrn_00240
[query] 18 - 254 (282)
[subject] 18 - 247 (256)
5e-36 155   40% Putative pathway specific activator tmn18 Streptomyces sp. NRRL 11266
96
Q2MGB3_STRGR
(Q2MGB3)
Jump to Fred_00260
[query] 1 - 273 (282)
[subject] 2 - 275 (611)
1e-35 154   41% Regulatory protein Streptomyces griseus
97
Q2PC66_STRAH
(Q2PC66)
Jump to Rubra_00240
[query] 1 - 269 (282)
[subject] 1 - 265 (266)
1e-35 154   39% Putative regulator rubRg1 Streptomyces achromogenes subsp. rubradiris
98
B8Y4G5_STRAU
(B8Y4G5)
[query] 14 - 266 (282)
[subject] 15 - 267 (278)
1e-35 154   40% SARP-family transcriptional regulator sa9 Streptomyces aureofaciens
99
D6MSY0_9ACTO
(D6MSY0)
[query] 1 - 255 (282)
[subject] 1 - 254 (270)
4e-35 152   41% SsfT1 ssfT1 Streptomyces sp. SF2575
100
E2D2K1_9BACT
(E2D2K1)
[query] 21 - 253 (282)
[subject] 29 - 257 (258)
4e-35 152   42% Pathway specific transcriptional regulator uncultured soil bacterium
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
O68913_9ACTO
(O68913)
[query] 1 - 282 (282)
[subject] 1 - 282 (282)
1e-159 563   100%
Product
Pathway specific regulator
Gene
frnG
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
3
B5UAT2_STRLA
(B5UAT2)
[query] 1 - 255 (282)
[subject] 1 - 255 (273)
7e-54 215   49%
Product
SARP family regulator
Gene
farR4
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
5
D7CHH7_STRBB
(D7CHH7)
[query] 1 - 263 (282)
[subject] 1 - 267 (271)
7e-52 208   47%
Product
SARP family pathway specific regulatory protein
Gene
SBI_03913
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
E1ARL5_STRAU
(E1ARL5)
[query] 1 - 255 (282)
[subject] 1 - 259 (292)
8e-52 208   49%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa37
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
7
E1ARN0_STRAU
(E1ARN0)
[query] 1 - 258 (282)
[subject] 1 - 258 (272)
2e-51 207   49%
Product
SARP family pathway specific regulatory protein
Gene
sa24
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
9
Q83X49_STRRO
(Q83X49)
[query] 1 - 261 (282)
[subject] 1 - 263 (289)
1e-50 204   48%
Product
SARP family regulator SrrW
Gene
srrW
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
10
Q9KHL3_9ACTO
(Q9KHL3)
Jump to Enter_00020
[query] 1 - 255 (282)
[subject] 1 - 251 (283)
3e-50 203   46%
Product
Putative transcriptional regulator EncF
Gene
encF
Organism
Streptomyces maritimus
1uniprot
Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000]
2uniprot[Pubmed] 11137817 [Medline] 20579517
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000]
3uniprot[Pubmed] 11948863 [Medline] 21942282
A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001]
[pubmed all]
11
Q9XCC4_STRFR
(Q9XCC4)
[query] 1 - 257 (282)
[subject] 1 - 260 (277)
3e-50 203   48%
Product
Hypothetical pathway specific regulatory protein TylS
Gene
tylS
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10467127 [Medline] 99398833
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae.(Chem. Biol.) [1999]
14
Q9L4V0_9ACTO
(Q9L4V0)
Jump to Acla_00170
[query] 1 - 265 (282)
[subject] 1 - 264 (272)
1e-49 201   45%
Product
Putative activator
Gene
aknO
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 11016846 [Medline] 20469061
A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000]
16
A2AXE3_STRCM
(A2AXE3)
[query] 1 - 255 (282)
[subject] 41 - 294 (313)
1e-49 201   44%
Product
Putative SARP family pathway-specific regulator
Gene
fnq4
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
19
Q8KSZ0_9ACTO
(Q8KSZ0)
Jump to Griseo_00020
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
5e-49 199   45%
Product
Putative transcriptional activator GrhR2
Gene
grhR2
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
20
Q0JW85_STRAM
(Q0JW85)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
9e-49 198   48%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0201
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
21
Q6VMH3_STRAM
(Q6VMH3)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
1e-48 197   48%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
22
Q1RQQ4_STRAM
(Q1RQQ4)
[query] 1 - 255 (282)
[subject] 1 - 258 (279)
1e-48 197   48%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
SAMT0181
SAMT0182
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
24
D9UBW9_STRPR
(D9UBW9)
[query] 1 - 257 (282)
[subject] 1 - 284 (300)
7e-48 195   44%
Product
SARP-type regulator
Gene
papR4
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
25
Q2L6C8_9ACTO
(Q2L6C8)
[query] 1 - 255 (282)
[subject] 71 - 324 (343)
8e-48 195   44%
Product
Putative transcriptional regulator
Gene
 
Organism
Streptomyces sp. KO-3988
1uniprot[Pubmed] 16452404
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.(J. Bacteriol.) [2006]
26
Q2PA02_9ACTO
(Q2PA02)
Jump to Stref_00130
[query] 1 - 259 (282)
[subject] 1 - 258 (290)
9e-48 194   46%
Product
SARP family regulator
Gene
stfRI
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
27
Q83X33_STRRO
(Q83X33)
[query] 1 - 259 (282)
[subject] 1 - 262 (273)
2e-47 194   43%
Product
SARP family regulator SrrZ
Gene
srrZ
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
29
D9UBT4_STRPR
(D9UBT4)
[query] 19 - 255 (282)
[subject] 4 - 239 (258)
3e-47 193   46%
Product
SARP-type regulator
Gene
cpp1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
30
D9UBV4_STRPR
(D9UBV4)
[query] 1 - 255 (282)
[subject] 1 - 255 (285)
2e-46 191   47%
Product
SARP-type regulator
Gene
papR1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
32
DNRI_STRPE
(P25047)
Jump to Adria_00210
[query] 1 - 275 (282)
[subject] 1 - 272 (272)
2e-46 191   44%
Product
Regulatory protein dnrI
Gene
dnrI
Organism
Streptomyces peucetius
1uniprot[Pubmed] 1729206 [Medline] 92104954
Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius.(J. Bacteriol.) [1992]
33
D7BZQ7_STRBB
(D7BZQ7)
[query] 1 - 255 (282)
[subject] 1 - 254 (274)
2e-46 190   48%
Product
SARP family pathway specific regulatory protein
Gene
SBI_06842
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
34
Q6VMH5_STRAM
(Q6VMH5)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
2e-46 190   44%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
35
Q1RQQ6_STRAM
(Q1RQQ6)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
2e-46 190   44%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
SAMT0179
SAMT0180
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
36
D1A6U2_THECD
(D1A6U2)
[query] 1 - 269 (282)
[subject] 2 - 266 (267)
3e-46 189   43%
Product
Transcriptional regulator, SARP family
Gene
Tcur_2801
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
37
Q0JW87_STRAM
(Q0JW87)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
8e-46 188   44%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0199
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
38
E2Q9D3_STRCL
(E2Q9D3)
[query] 1 - 264 (282)
[subject] 1 - 265 (278)
8e-46 188   44%
Product
SARP family pathway specific regulatory protein
Gene
SCLAV_0477
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
39
Q9KWX4_STRAM
(Q9KWX4)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
8e-46 188   44%
Product
Regulator (SAR)
Gene
sar
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 10628855 [Medline] 20092477
Cloning and characterization of a regulatory gene of the SARP family and its flanking region from Streptomyces ambofaciens.(Mol. Gen. Genet.) [1999]
40
C9ZCD2_STRSW
(C9ZCD2)
[query] 1 - 267 (282)
[subject] 1 - 268 (278)
1e-45 187   43%
Product
Putative regulatory protein
Gene
SCAB_63171
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
44
B0LIZ8_9ACTO
(B0LIZ8)
[query] 1 - 251 (282)
[subject] 1 - 253 (276)
3e-45 186   44%
Product
Lct15
Gene
lct15
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
46
A7DWL6_STRTE
(A7DWL6)
[query] 1 - 263 (282)
[subject] 1 - 266 (613)
4e-45 186   43%
Product
Putative transcriptional activator, SARP family
Gene
llpRIV
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
47
E1ARL7_STRAU
(E1ARL7)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
4e-45 186   43%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa35
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
48
B5UAT1_STRLA
(B5UAT1)
[query] 1 - 255 (282)
[subject] 1 - 254 (273)
4e-45 186   44%
Product
SARP family regulator
Gene
farR3
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
49
Q54494_STRNO
(Q54494)
Jump to Nogl_00360
[query] 1 - 259 (282)
[subject] 28 - 277 (665)
5e-45 185   43%
Product
Snora
Gene
snorA
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
50
Q83X29_STRRO
(Q83X29)
[query] 1 - 257 (282)
[subject] 1 - 260 (276)
7e-45 185   44%
Product
SARP family regulator SrrY
Gene
srrY
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
51
E2EKL8_9ACTO
(E2EKL8)
[query] 1 - 272 (282)
[subject] 2 - 274 (610)
9e-45 185   43%
Product
Regulator
Gene
sanR1
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
53
Q4R0M3_STRCX
(Q4R0M3)
Jump to Chart_00090
[query] 46 - 255 (282)
[subject] 1 - 209 (216)
1e-44 184   46%
Product
ChaR1 protein
Gene
chaR1
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
55
E5DUG1_9NOCA
(E5DUG1)
[query] 1 - 257 (282)
[subject] 2 - 260 (299)
1e-43 181   43%
Product
NocP
Gene
nocP
Organism
Nocardia sp. ATCC 202099
1uniprot[Pubmed] 20473441
Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.(Mol. Biosyst.) [2010]
56
E4NBI0_KITSK
(E4NBI0)
[query] 1 - 263 (282)
[subject] 1 - 260 (269)
2e-43 180   43%
Product
Putative AfsR family transcriptional regulator
Gene
KSE_27490
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
57
D2AY68_STRRD
(D2AY68)
[query] 1 - 260 (282)
[subject] 1 - 258 (621)
3e-43 179   42%
Product
Transcriptional regulator, SARP family
Gene
Sros_4174
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
58
Q8KSZ1_9ACTO
(Q8KSZ1)
Jump to Griseo_00010
[query] 1 - 251 (282)
[subject] 1 - 254 (273)
4e-43 179   45%
Product
Putative transcriptional activator GrhR1
Gene
grhR1
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
60
Q8VWA7_9ACTO
(Q8VWA7)
[query] 1 - 254 (282)
[subject] 1 - 253 (280)
5e-43 179   44%
Product
AclI
Gene
aclI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
61
D8I4K7_AMYMU
(D8I4K7)
[query] 1 - 255 (282)
[subject] 1 - 249 (617)
5e-43 179   42%
Product
SARP family transcriptional regulator
Gene
AMED_5421
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
62
Q9L545_9ACTO
(Q9L545)
Jump to Acla_00140
[query] 1 - 254 (282)
[subject] 1 - 253 (280)
6e-43 179   44%
Product
AknI
Gene
aknI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
63
Q9LBV5_STRVG
(Q9LBV5)
Jump to Virg_00290
[query] 1 - 255 (282)
[subject] 1 - 255 (271)
1e-42 177   46%
Product
Orf2
Gene
 
Organism
Streptomyces virginiae
1uniprot[Pubmed] 10792718 [Medline] 20253310
Identification of an AfsA homologue (BarX) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis, virginiamycin biosynthesis and virginiamycin M1 resistance.(Mol. Microbiol.) [2000]
65
D2SZ12_MICEC
(D2SZ12)
[query] 1 - 265 (282)
[subject] 1 - 272 (293)
3e-42 176   42%
Product
Transcriptional regulator
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
66
C7PY63_CATAD
(C7PY63)
[query] 1 - 252 (282)
[subject] 1 - 251 (252)
8e-42 175   42%
Product
Transcriptional regulator, SARP family
Gene
Caci_6503
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
68
C9ZCB7_STRSW
(C9ZCB7)
[query] 1 - 255 (282)
[subject] 1 - 246 (919)
1e-41 174   44%
Product
Putative transcriptional activator
Gene
SCAB_63021
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
69
B6SEG7_9ACTO
(B6SEG7)
Jump to Alnu_00220
[query] 1 - 253 (282)
[subject] 1 - 252 (271)
2e-41 174   43%
Product
AlnR3 SARP family regulator
Gene
alnR3
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
70
D7CH46_STRBB
(D7CH46)
[query] 1 - 255 (282)
[subject] 1 - 249 (617)
4e-41 172   42%
Product
Transcriptional regulator, SARP family protein
Gene
SBI_01760
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
73
C7N0E0_SACVD
(C7N0E0)
[query] 1 - 254 (282)
[subject] 1 - 250 (631)
1e-40 171   43%
Product
DNA-binding transcriptional activator of the SARP family
Gene
Svir_33780
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
76
Q67G41_9ACTO
(Q67G41)
Jump to Heda_00170
[query] 1 - 259 (282)
[subject] 1 - 266 (272)
2e-40 170   43%
Product
Putative regulatory protein
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
77
Q7WT17_9ACTO
(Q7WT17)
Jump to Medem_00250
[query] 1 - 252 (282)
[subject] 1 - 249 (258)
3e-40 170   42%
Product
Pathway-specific transcriptional activator (SARP)
Gene
med-ORF11
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
80
C0JWC2_9ACTO
(C0JWC2)
Jump to Polk_00270
[query] 1 - 256 (282)
[subject] 1 - 254 (270)
2e-39 167   42%
Product
PokR2
Gene
pokR2
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
81
E2Q9B8_STRCL
(E2Q9B8)
[query] 1 - 276 (282)
[subject] 1 - 273 (931)
3e-38 163   40%
Product
Putative regulatory protein AfsR-like protein
Gene
SCLAV_0462
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
83
C7QAG9_CATAD
(C7QAG9)
[query] 14 - 254 (282)
[subject] 13 - 249 (261)
4e-38 163   42%
Product
Transcriptional regulator, SARP family
Gene
Caci_3563
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
86
F4FBT2_VERMA
(F4FBT2)
[query] 1 - 256 (282)
[subject] 2 - 250 (260)
1e-37 161   41%
Product
SARP family transcriptional regulator
Gene
VAB18032_18150
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
87
Q194R8_STRAA
(Q194R8)
Jump to Mith_00020
[query] 3 - 252 (282)
[subject] 1 - 248 (276)
1e-37 161   40%
Product
Mithramycin regulator MtmR
Gene
mtmR
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 9882681 [Medline] 99102230
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.(J. Bacteriol.) [1999]
6uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
7uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
8uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
9uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
10uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
11uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
12uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
13uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
14uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
15uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
16uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
17uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
18uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
19uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
20uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
21uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
88
Q9ZA48_STRVN
(Q9ZA48)
Jump to Grana_00030
[query] 1 - 266 (282)
[subject] 1 - 278 (283)
4e-37 159   41%
Product
Pathway-specific transcriptional activator
Gene
gra-orf9
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
90
E1ARN1_STRAU
(E1ARN1)
[query] 1 - 255 (282)
[subject] 1 - 249 (268)
6e-37 159   39%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa23
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
94
D2AQB1_STRRD
(D2AQB1)
[query] 1 - 254 (282)
[subject] 1 - 242 (950)
2e-36 157   42%
Product
Transcriptional regulator, SARP family
Gene
Sros_1461
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
96
Q2MGB3_STRGR
(Q2MGB3)
Jump to Fred_00260
[query] 1 - 273 (282)
[subject] 2 - 275 (611)
1e-35 154   41%
Product
Regulatory protein
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 16305230
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005]
97
Q2PC66_STRAH
(Q2PC66)
Jump to Rubra_00240
[query] 1 - 269 (282)
[subject] 1 - 265 (266)
1e-35 154   39%
Product
Putative regulator
Gene
rubRg1
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
98
B8Y4G5_STRAU
(B8Y4G5)
[query] 14 - 266 (282)
[subject] 15 - 267 (278)
1e-35 154   40%
Product
SARP-family transcriptional regulator
Gene
sa9
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 20490753
Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.(Folia Microbiol. (Praha)) [2010]
99
D6MSY0_9ACTO
(D6MSY0)
[query] 1 - 255 (282)
[subject] 1 - 254 (270)
4e-35 152   41%
Product
SsfT1
Gene
ssfT1
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
100
E2D2K1_9BACT
(E2D2K1)
[query] 21 - 253 (282)
[subject] 29 - 257 (258)
4e-35 152   42%
Product
Pathway specific transcriptional regulator
Gene
 
Organism
uncultured soil bacterium
1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]