BLAST table : Medem_00250

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q7WT17_9ACTO
(Q7WT17)		 
[query] 1 - 258 (258)
[subject] 1 - 258 (258)
 1e-147 525   100% Pathway-specific transcriptional activator (SARP) med-ORF11 Streptomyces sp. AM-7161
2
 B8Y4G5_STRAU
(B8Y4G5)		 
[query] 1 - 256 (258)
[subject] 1 - 259 (278)
 1e-71 274   54% SARP-family transcriptional regulator sa9 Streptomyces aureofaciens
3
 Q1MWN3_STRLA
(Q1MWN3)		 
[query] 1 - 250 (258)
[subject] 1 - 250 (262)
 8e-68 261   53% Putative pathway-specific transcriptional activator bpsB Streptomyces lavendulae subsp. lavendulae
4
 Q93RY4_STRCO
(Q93RY4)		 
[query] 6 - 250 (258)
[subject] 1 - 245 (276)
 2e-62 243   50% Putative regulatory protein SCO6288 Streptomyces coelicolor
5
 D6EJL1_STRLI
(D6EJL1)		 
[query] 6 - 250 (258)
[subject] 1 - 245 (276)
 2e-62 243   50% Regulatory protein SSPG_01343 Streptomyces lividans TK24
6
 D9W5A7_9ACTO
(D9W5A7)		 
[query] 1 - 253 (258)
[subject] 1 - 253 (261)
 5e-62 242   52% SARP-family transcriptional regulator SSNG_07337 Streptomyces sp. C
7
 D9XDJ2_STRVR
(D9XDJ2)		 
[query] 1 - 249 (258)
[subject] 1 - 249 (287)
 1e-57 227   44% SARP family pathway specific regulatory protein SSQG_00889 Streptomyces viridochromogenes DSM 40736
8
 D3CXU3_9ACTO
(D3CXU3)		 
[query] 1 - 248 (258)
[subject] 1 - 247 (248)
 2e-55 219   47% Transcriptional regulator, SARP family FrEUN1fDRAFT_2363 Frankia sp. EUN1f
9
 B1W5Q7_STRGG
(B1W5Q7)		 
[query] 1 - 249 (258)
[subject] 1 - 249 (280)
 1e-54 217   44% Putative SARP-family pathway specific regulatory protein SGR_6385 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
10
 E3J3Q3_FRASU
(E3J3Q3)		 
[query] 2 - 248 (258)
[subject] 74 - 319 (322)
 6e-52 208   45% Transcriptional regulator, SARP family FraEuI1c_1323 Frankia sp. (strain EuI1c)
11
 D2AY68_STRRD
(D2AY68)		 
[query] 1 - 249 (258)
[subject] 1 - 244 (621)
 3e-50 202   46% Transcriptional regulator, SARP family Sros_4174 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
12
 D9VWN5_9ACTO
(D9VWN5)		 
[query] 1 - 250 (258)
[subject] 1 - 251 (276)
 3e-49 199   44% SARP family pathway specific regulatory protein SSNG_04495 Streptomyces sp. C
13
 D6EWA9_STRLI
(D6EWA9)		 
[query] 1 - 249 (258)
[subject] 1 - 249 (255)
 4e-49 199   44% Actinorhodin cluster activator protein SSPG_02604 Streptomyces lividans TK24
14
 ACT24_STRCO
(P46106)		 Jump to Actino_00160 
[query] 1 - 249 (258)
[subject] 1 - 249 (255)
 4e-49 199   44% Probable actinorhodin operon activatory protein actII-4
SCO5085
SCBAC28G1.11		 Streptomyces coelicolor
15
 Q2PC40_STRAH
(Q2PC40)		 Jump to Rubra_00500 
[query] 1 - 248 (258)
[subject] 1 - 247 (290)
 2e-48 197   49% Putative transcription activator rubRg3 Streptomyces achromogenes subsp. rubradiris
16
 D8I4K7_AMYMU
(D8I4K7)		 
[query] 1 - 249 (258)
[subject] 1 - 246 (617)
 1e-47 194   44% SARP family transcriptional regulator AMED_5421 Amycolatopsis mediterranei (strain U-32)
17
 Q9XCC4_STRFR
(Q9XCC4)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (277)
 1e-47 194   44% Hypothetical pathway specific regulatory protein TylS tylS Streptomyces fradiae
Streptomyces roseoflavus
18
 D7CH46_STRBB
(D7CH46)		 
[query] 1 - 248 (258)
[subject] 1 - 245 (617)
 2e-45 186   45% Transcriptional regulator, SARP family protein SBI_01760 Streptomyces bingchenggensis (strain BCW-1)
19
 E8RWU1_MICSL
(E8RWU1)		 
[query] 1 - 249 (258)
[subject] 1 - 244 (651)
 6e-45 185   43% Transcriptional regulator, SARP family ML5_4430 Micromonospora sp. (strain L5)
20
 D9T288_MICAI
(D9T288)		 
[query] 1 - 249 (258)
[subject] 1 - 244 (651)
 6e-45 185   43% Transcriptional activator domain Micau_3991 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
21
 B0LIZ8_9ACTO
(B0LIZ8)		 
[query] 1 - 258 (258)
[subject] 1 - 263 (276)
 8e-45 184   41% Lct15 lct15 Streptomyces rishiriensis
22
 D1A6U2_THECD
(D1A6U2)		 
[query] 1 - 249 (258)
[subject] 2 - 249 (267)
 1e-44 184   41% Transcriptional regulator, SARP family Tcur_2801 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
23
 D9VWN4_9ACTO
(D9VWN4)		 
[query] 2 - 248 (258)
[subject] 13 - 258 (264)
 3e-44 183   41% Predicted protein SSNG_04494 Streptomyces sp. C
24
 Q933S1_STRAW
(Q933S1)		 
[query] 1 - 248 (258)
[subject] 2 - 248 (270)
 6e-44 182   44% Putative regulatory protein
Putative regulatory protein protein
Regulatory protein		 putative regulatory protein
SAV2369
SAV_2369		 Streptomyces avermitilis
25
 D9W572_9ACTO
(D9W572)		 
[query] 1 - 248 (258)
[subject] 1 - 251 (274)
 6e-44 182   44% SARP family regulator SSNG_07302 Streptomyces sp. C
26
 Q6VMH3_STRAM
(Q6VMH3)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 6e-44 182   43% Putative SARP family pathway specific regulatory protein alpV Streptomyces ambofaciens
27
 Q1RQQ4_STRAM
(Q1RQQ4)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 6e-44 182   43% Putative SARP family pathway specific regulatory protein alpV
SAMT0181
SAMT0182		 Streptomyces ambofaciens ATCC 23877
28
 Q0JW85_STRAM
(Q0JW85)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 7e-44 181   43% Putative SARP family pathway specific regulatory protein DSMT0201 Streptomyces ambofaciens
29
 D6MSY0_9ACTO
(D6MSY0)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (270)
 7e-44 181   44% SsfT1 ssfT1 Streptomyces sp. SF2575
30
 D1XHA5_9ACTO
(D1XHA5)		 
[query] 1 - 248 (258)
[subject] 2 - 248 (270)
 8e-44 181   44% Transcriptional regulator, SARP family SACTEDRAFT_2156 Streptomyces sp. SA3_actE
31
 Q2PC66_STRAH
(Q2PC66)		 Jump to Rubra_00240 
[query] 1 - 251 (258)
[subject] 1 - 250 (266)
 9e-44 181   41% Putative regulator rubRg1 Streptomyces achromogenes subsp. rubradiris
32
 B5HIW5_STRPR
(B5HIW5)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 1e-43 181   43% Transcriptional activator domain-containing protein SSDG_05102 Streptomyces pristinaespiralis ATCC 25486
33
 E1ARL5_STRAU
(E1ARL5)		 
[query] 1 - 248 (258)
[subject] 1 - 255 (292)
 1e-43 181   42% Putative SARP family pathway specific regulatory protein sa37 Streptomyces aureofaciens
34
 B5UAT2_STRLA
(B5UAT2)		 
[query] 1 - 248 (258)
[subject] 1 - 251 (273)
 1e-43 181   44% SARP family regulator farR4 Streptomyces lavendulae
35
 D9W5M6_9ACTO
(D9W5M6)		 
[query] 1 - 249 (258)
[subject] 1 - 250 (1010)
 2e-43 180   44% Predicted protein SSNG_07456 Streptomyces sp. C
36
 D8I3B2_AMYMU
(D8I3B2)		 
[query] 1 - 249 (258)
[subject] 19 - 266 (271)
 3e-43 179   41% SARP family transcriptional regulator AMED_6875 Amycolatopsis mediterranei (strain U-32)
37
 Q9L545_9ACTO
(Q9L545)		 Jump to Acla_00140 
[query] 1 - 249 (258)
[subject] 1 - 251 (280)
 3e-43 179   41% AknI aknI Streptomyces galilaeus
38
 Q83X49_STRRO
(Q83X49)		 
[query] 1 - 249 (258)
[subject] 1 - 254 (289)
 3e-43 179   42% SARP family regulator SrrW srrW Streptomyces rochei
Streptomyces parvullus
39
 Q8VWA7_9ACTO
(Q8VWA7)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (280)
 3e-43 179   41% AclI aclI Streptomyces galilaeus
40
 B6SEG7_9ACTO
(B6SEG7)		 Jump to Alnu_00220 
[query] 1 - 249 (258)
[subject] 1 - 251 (271)
 1e-42 177   42% AlnR3 SARP family regulator alnR3 Streptomyces sp. CM020
41
 E4NBI0_KITSK
(E4NBI0)		 
[query] 1 - 248 (258)
[subject] 1 - 248 (269)
 2e-42 177   44% Putative AfsR family transcriptional regulator KSE_27490 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
42
 Q83X33_STRRO
(Q83X33)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 2e-42 176   41% SARP family regulator SrrZ srrZ Streptomyces rochei
Streptomyces parvullus
43
 D9W573_9ACTO
(D9W573)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 4e-42 176   41% SARP family regulator SSNG_07303 Streptomyces sp. C
44
 D6AAS1_9ACTO
(D6AAS1)		 
[query] 1 - 252 (258)
[subject] 1 - 260 (290)
 4e-42 176   42% SARP family pathway specific regulatory protein SSFG_07841 Streptomyces ghanaensis ATCC 14672
45
 F4FBT2_VERMA
(F4FBT2)		 
[query] 1 - 248 (258)
[subject] 2 - 245 (260)
 4e-42 176   40% SARP family transcriptional regulator VAB18032_18150 Verrucosispora maris (strain AB-18-032)
46
 C7N0E0_SACVD
(C7N0E0)		 
[query] 1 - 248 (258)
[subject] 1 - 247 (631)
 6e-42 175   43% DNA-binding transcriptional activator of the SARP family Svir_33780 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
47
 E2Q9D3_STRCL
(E2Q9D3)		 
[query] 1 - 249 (258)
[subject] 1 - 250 (278)
 7e-42 175   43% SARP family pathway specific regulatory protein SCLAV_0477 Streptomyces clavuligerus ATCC 27064
48
 D9UBV4_STRPR
(D9UBV4)		 
[query] 1 - 249 (258)
[subject] 1 - 252 (285)
 1e-41 174   42% SARP-type regulator papR1 Streptomyces pristinaespiralis
49
 D6X7H8_STRPR
(D6X7H8)		 
[query] 1 - 249 (258)
[subject] 1 - 252 (285)
 1e-41 174   42% SARP family regulator SSDG_07486 Streptomyces pristinaespiralis ATCC 25486
50
 E1ARL7_STRAU
(E1ARL7)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (273)
 2e-41 173   41% Putative SARP family pathway specific regulatory protein sa35 Streptomyces aureofaciens
51
 D9UBT4_STRPR
(D9UBT4)		 
[query] 18 - 248 (258)
[subject] 2 - 235 (258)
 2e-41 173   43% SARP-type regulator cpp1 Streptomyces pristinaespiralis
52
 B5G879_9ACTO
(B5G879)		 
[query] 1 - 249 (258)
[subject] 2 - 252 (281)
 3e-41 172   40% Transcriptional regulatory protein, C SSBG_00487 Streptomyces sp. SPB74
53
 Q2L6C8_9ACTO
(Q2L6C8)		 
[query] 1 - 248 (258)
[subject] 71 - 320 (343)
 6e-41 172   40% Putative transcriptional regulator Streptomyces sp. KO-3988
54
 D6AAR9_9ACTO
(D6AAR9)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 6e-41 172   39% Putative uncharacterized protein SSFG_07839 Streptomyces ghanaensis ATCC 14672
55
 Q54494_STRNO
(Q54494)		 Jump to Nogl_00360 
[query] 1 - 249 (258)
[subject] 28 - 270 (665)
 1e-40 171   41% Snora snorA Streptomyces nogalater
56
 O68913_9ACTO
(O68913)		 Jump to Fren_00070 
[query] 1 - 249 (258)
[subject] 1 - 252 (282)
 1e-40 171   42% Pathway specific regulator frnG Streptomyces roseofulvus
57
 Q9LBV5_STRVG
(Q9LBV5)		 Jump to Virg_00290 
[query] 1 - 248 (258)
[subject] 1 - 251 (271)
 1e-40 171   42% Orf2 Streptomyces virginiae
58
 C9ZCB7_STRSW
(C9ZCB7)		 
[query] 1 - 249 (258)
[subject] 1 - 243 (919)
 2e-40 170   42% Putative transcriptional activator SCAB_63021 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
59
 E2EKL8_9ACTO
(E2EKL8)		 
[query] 1 - 248 (258)
[subject] 2 - 252 (610)
 2e-40 170   41% Regulator sanR1 Streptomyces sp. SANK 61196
60
 D9UKN0_9ACTO
(D9UKN0)		 
[query] 1 - 249 (258)
[subject] 1 - 252 (282)
 2e-40 170   42% Pathway specific regulator SSLG_05746 Streptomyces sp. SPB78
61
 E1ARN0_STRAU
(E1ARN0)		 
[query] 1 - 248 (258)
[subject] 1 - 251 (272)
 2e-40 170   42% SARP family pathway specific regulatory protein sa24 Streptomyces aureofaciens
62
 Q8KSZ0_9ACTO
(Q8KSZ0)		 Jump to Griseo_00020 
[query] 1 - 249 (258)
[subject] 1 - 251 (273)
 3e-40 169   40% Putative transcriptional activator GrhR2 grhR2 Streptomyces sp. JP95
63
 D9UBW9_STRPR
(D9UBW9)		 
[query] 1 - 248 (258)
[subject] 1 - 278 (300)
 4e-40 169   38% SARP-type regulator papR4 Streptomyces pristinaespiralis
64
 B5UAT1_STRLA
(B5UAT1)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 7e-40 168   40% SARP family regulator farR3 Streptomyces lavendulae
65
 A7DWL6_STRTE
(A7DWL6)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (613)
 7e-40 168   42% Putative transcriptional activator, SARP family llpRIV Streptomyces tendae
66
 Q83X29_STRRO
(Q83X29)		 
[query] 1 - 252 (258)
[subject] 1 - 262 (276)
 8e-40 168   40% SARP family regulator SrrY srrY Streptomyces rochei
Streptomyces parvullus
67
 A2AXE3_STRCM
(A2AXE3)		 
[query] 1 - 248 (258)
[subject] 41 - 290 (313)
 9e-40 168   39% Putative SARP family pathway-specific regulator fnq4 Streptomyces cinnamonensis
68
 Q6VMH5_STRAM
(Q6VMH5)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 9e-40 168   40% Putative SARP family pathway specific regulatory protein alpT Streptomyces ambofaciens
69
 Q1RQQ6_STRAM
(Q1RQQ6)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 9e-40 168   40% Putative SARP family pathway specific regulatory protein alpT
SAMT0179
SAMT0180		 Streptomyces ambofaciens ATCC 23877
70
 Q0JW87_STRAM
(Q0JW87)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 1e-39 168   40% Putative SARP family pathway specific regulatory protein DSMT0199 Streptomyces ambofaciens
71
 E2D2K1_9BACT
(E2D2K1)		 
[query] 1 - 248 (258)
[subject] 6 - 255 (258)
 1e-39 167   38% Pathway specific transcriptional regulator uncultured soil bacterium
72
 DNRI_STRPE
(P25047)		 Jump to Adria_00210 
[query] 1 - 248 (258)
[subject] 1 - 250 (272)
 3e-39 166   38% Regulatory protein dnrI dnrI Streptomyces peucetius
73
 E8W955_STRFA
(E8W955)		 
[query] 19 - 252 (258)
[subject] 21 - 252 (268)
 3e-39 166   41% Transcriptional regulator, SARP family Sfla_5321 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
74
 Q9KWX4_STRAM
(Q9KWX4)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 4e-39 166   40% Regulator (SAR) sar Streptomyces ambofaciens
75
 D2SZ12_MICEC
(D2SZ12)		 
[query] 1 - 249 (258)
[subject] 1 - 256 (293)
 5e-39 165   40% Transcriptional regulator Micromonospora echinospora subsp. challisensis
76
 Q8KY34_STRCU
(Q8KY34)		 
[query] 1 - 248 (258)
[subject] 16 - 273 (661)
 9e-39 164   41% RubS rubS Streptomyces collinus
77
 E5RLL0_9ACTO
(E5RLL0)		 
[query] 1 - 248 (258)
[subject] 1 - 246 (635)
 1e-38 164   42% Putative transcriptional regulator pnxR2 Streptomyces sp. TA-0256
78
 Q8KSZ1_9ACTO
(Q8KSZ1)		 Jump to Griseo_00010 
[query] 1 - 257 (258)
[subject] 1 - 272 (273)
 2e-38 164   39% Putative transcriptional activator GrhR1 grhR1 Streptomyces sp. JP95
79
 Q67G41_9ACTO
(Q67G41)		 Jump to Heda_00170 
[query] 1 - 248 (258)
[subject] 1 - 250 (272)
 2e-38 164   41% Putative regulatory protein Streptomyces griseoruber
80
 Q70J84_STRGR
(Q70J84)		 Jump to Chro_00140 
[query] 1 - 248 (258)
[subject] 10 - 262 (300)
 2e-38 163   40% Transcriptional regulator cmmRI Streptomyces griseus subsp. griseus
81
 E3T487_9ACTO
(E3T487)		 
[query] 5 - 249 (258)
[subject] 3 - 256 (278)
 3e-38 163   39% Pathway-specific transcriptional activator gra-orf9 Streptomyces vietnamensis
82
 B1GSM4_9ACTO
(B1GSM4)		 Jump to Bena_00140 
[query] 1 - 248 (258)
[subject] 7 - 252 (656)
 3e-38 163   42% BenR protein benR Streptomyces sp. A2991200
83
 E5DUG1_9NOCA
(E5DUG1)		 
[query] 1 - 248 (258)
[subject] 2 - 254 (299)
 4e-38 162   38% NocP nocP Nocardia sp. ATCC 202099
84
 Q9KHL3_9ACTO
(Q9KHL3)		 Jump to Enter_00020 
[query] 1 - 249 (258)
[subject] 1 - 248 (283)
 1e-37 161   39% Putative transcriptional regulator EncF encF Streptomyces maritimus
85
 A1C183_9ACTO
(A1C183)		 Jump to Aran_00150 
[query] 1 - 249 (258)
[subject] 3 - 253 (269)
 1e-37 160   40% Pathway specific transcription activator Streptomyces echinatus
86
 E2Q9B8_STRCL
(E2Q9B8)		 
[query] 1 - 249 (258)
[subject] 1 - 254 (931)
 1e-37 160   40% Putative regulatory protein AfsR-like protein SCLAV_0462 Streptomyces clavuligerus ATCC 27064
87
 Q194R8_STRAA
(Q194R8)		 Jump to Mith_00020 
[query] 5 - 252 (258)
[subject] 3 - 251 (276)
 1e-37 160   40% Mithramycin regulator MtmR mtmR Streptomyces argillaceus
88
 C7PY63_CATAD
(C7PY63)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (252)
 1e-37 160   38% Transcriptional regulator, SARP family Caci_6503 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
89
 B0LJ06_9ACTO
(B0LJ06)		 
[query] 1 - 248 (258)
[subject] 1 - 248 (625)
 2e-37 160   41% Lct23 lct23 Streptomyces rishiriensis
90
 D9W557_9ACTO
(D9W557)		 
[query] 1 - 249 (258)
[subject] 1 - 252 (274)
 3e-37 159   40% SARP family regulator SSNG_07287 Streptomyces sp. C
91
 D6AXN0_9ACTO
(D6AXN0)		 
[query] 3 - 248 (258)
[subject] 16 - 264 (286)
 4e-37 159   38% Putative uncharacterized protein SSHG_05322 Streptomyces albus J1074
92
 E3JBV0_FRASU
(E3JBV0)		 
[query] 1 - 249 (258)
[subject] 22 - 266 (282)
 4e-37 159   38% Transcriptional regulator, SARP family FraEuI1c_4261 Frankia sp. (strain EuI1c)
93
 F2RDR4_STRVP
(F2RDR4)		 
[query] 1 - 249 (258)
[subject] 5 - 255 (1018)
 5e-37 159   40% Putative uncharacterized protein SVEN_6270 SVEN_6270 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
94
 Q0RI37_FRAAA
(Q0RI37)		 
[query] 1 - 249 (258)
[subject] 4 - 251 (456)
 7e-37 158   40% Putative transcriptional regulator FRAAL4193 Frankia alni (strain ACN14a)
95
 Q4R0M3_STRCX
(Q4R0M3)		 Jump to Chart_00090 
[query] 47 - 258 (258)
[subject] 1 - 215 (216)
 7e-37 158   42% ChaR1 protein chaR1 Streptomyces chartreusis
96
 A8M887_SALAI
(A8M887)		 
[query] 1 - 248 (258)
[subject] 1 - 241 (654)
 8e-37 158   36% Transcriptional regulator, SARP family Sare_3099 Salinispora arenicola (strain CNS-205)
97
 D9VBL6_9ACTO
(D9VBL6)		 
[query] 2 - 249 (258)
[subject] 59 - 303 (331)
 1e-36 157   37% Predicted protein SSMG_01149 Streptomyces sp. AA4
98
 C6FX55_STRAS
(C6FX55)		 
[query] 1 - 248 (258)
[subject] 53 - 305 (323)
 2e-36 157   36% NosP nosP Streptomyces actuosus
99
 C9ZCD2_STRSW
(C9ZCD2)		 
[query] 1 - 249 (258)
[subject] 1 - 250 (278)
 3e-36 156   41% Putative regulatory protein SCAB_63171 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
100
 E3JAP5_FRASU
(E3JAP5)		 
[query] 1 - 248 (258)
[subject] 1 - 245 (258)
 4e-36 155   37% Transcriptional regulator, SARP family FraEuI1c_4238 Frankia sp. (strain EuI1c)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q7WT17_9ACTO
(Q7WT17)		 
[query] 1 - 258 (258)
[subject] 1 - 258 (258)
 1e-147 525   100%
Product
Pathway-specific transcriptional activator (SARP)
Gene
med-ORF11
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
2
 B8Y4G5_STRAU
(B8Y4G5)		 
[query] 1 - 256 (258)
[subject] 1 - 259 (278)
 1e-71 274   54%
Product
SARP-family transcriptional regulator
Gene
sa9
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 20490753
Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.(Folia Microbiol. (Praha)) [2010]
3
 Q1MWN3_STRLA
(Q1MWN3)		 
[query] 1 - 250 (258)
[subject] 1 - 250 (262)
 8e-68 261   53%
Product
Putative pathway-specific transcriptional activator
Gene
bpsB
Organism
Streptomyces lavendulae subsp. lavendulae
1uniprot[Pubmed] 17237222
Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis.(J. Biol. Chem.) [2007]
4
 Q93RY4_STRCO
(Q93RY4)		 
[query] 6 - 250 (258)
[subject] 1 - 245 (276)
 2e-62 243   50%
Product
Putative regulatory protein
Gene
SCO6288
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
9
 B1W5Q7_STRGG
(B1W5Q7)		 
[query] 1 - 249 (258)
[subject] 1 - 249 (280)
 1e-54 217   44%
Product
Putative SARP-family pathway specific regulatory protein
Gene
SGR_6385
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
11
 D2AY68_STRRD
(D2AY68)		 
[query] 1 - 249 (258)
[subject] 1 - 244 (621)
 3e-50 202   46%
Product
Transcriptional regulator, SARP family
Gene
Sros_4174
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
14
 ACT24_STRCO
(P46106)		 Jump to Actino_00160 
[query] 1 - 249 (258)
[subject] 1 - 249 (255)
 4e-49 199   44%
Product
Probable actinorhodin operon activatory protein
Gene
actII-4
SCO5085
SCBAC28G1.11
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1878971 [Medline] 91347376
The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces.(Cell) [1991]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
15
 Q2PC40_STRAH
(Q2PC40)		 Jump to Rubra_00500 
[query] 1 - 248 (258)
[subject] 1 - 247 (290)
 2e-48 197   49%
Product
Putative transcription activator
Gene
rubRg3
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
16
 D8I4K7_AMYMU
(D8I4K7)		 
[query] 1 - 249 (258)
[subject] 1 - 246 (617)
 1e-47 194   44%
Product
SARP family transcriptional regulator
Gene
AMED_5421
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
17
 Q9XCC4_STRFR
(Q9XCC4)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (277)
 1e-47 194   44%
Product
Hypothetical pathway specific regulatory protein TylS
Gene
tylS
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10467127 [Medline] 99398833
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae.(Chem. Biol.) [1999]
18
 D7CH46_STRBB
(D7CH46)		 
[query] 1 - 248 (258)
[subject] 1 - 245 (617)
 2e-45 186   45%
Product
Transcriptional regulator, SARP family protein
Gene
SBI_01760
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
21
 B0LIZ8_9ACTO
(B0LIZ8)		 
[query] 1 - 258 (258)
[subject] 1 - 263 (276)
 8e-45 184   41%
Product
Lct15
Gene
lct15
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
22
 D1A6U2_THECD
(D1A6U2)		 
[query] 1 - 249 (258)
[subject] 2 - 249 (267)
 1e-44 184   41%
Product
Transcriptional regulator, SARP family
Gene
Tcur_2801
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
24
 Q933S1_STRAW
(Q933S1)		 
[query] 1 - 248 (258)
[subject] 2 - 248 (270)
 6e-44 182   44%
Product
Putative regulatory protein
Putative regulatory protein protein
Regulatory protein
Gene
putative regulatory protein
SAV2369
SAV_2369
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
26
 Q6VMH3_STRAM
(Q6VMH3)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 6e-44 182   43%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
27
 Q1RQQ4_STRAM
(Q1RQQ4)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 6e-44 182   43%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
SAMT0181
SAMT0182
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
28
 Q0JW85_STRAM
(Q0JW85)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (279)
 7e-44 181   43%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0201
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
29
 D6MSY0_9ACTO
(D6MSY0)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (270)
 7e-44 181   44%
Product
SsfT1
Gene
ssfT1
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
31
 Q2PC66_STRAH
(Q2PC66)		 Jump to Rubra_00240 
[query] 1 - 251 (258)
[subject] 1 - 250 (266)
 9e-44 181   41%
Product
Putative regulator
Gene
rubRg1
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
33
 E1ARL5_STRAU
(E1ARL5)		 
[query] 1 - 248 (258)
[subject] 1 - 255 (292)
 1e-43 181   42%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa37
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
34
 B5UAT2_STRLA
(B5UAT2)		 
[query] 1 - 248 (258)
[subject] 1 - 251 (273)
 1e-43 181   44%
Product
SARP family regulator
Gene
farR4
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
36
 D8I3B2_AMYMU
(D8I3B2)		 
[query] 1 - 249 (258)
[subject] 19 - 266 (271)
 3e-43 179   41%
Product
SARP family transcriptional regulator
Gene
AMED_6875
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
37
 Q9L545_9ACTO
(Q9L545)		 Jump to Acla_00140 
[query] 1 - 249 (258)
[subject] 1 - 251 (280)
 3e-43 179   41%
Product
AknI
Gene
aknI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
38
 Q83X49_STRRO
(Q83X49)		 
[query] 1 - 249 (258)
[subject] 1 - 254 (289)
 3e-43 179   42%
Product
SARP family regulator SrrW
Gene
srrW
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
39
 Q8VWA7_9ACTO
(Q8VWA7)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (280)
 3e-43 179   41%
Product
AclI
Gene
aclI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
40
 B6SEG7_9ACTO
(B6SEG7)		 Jump to Alnu_00220 
[query] 1 - 249 (258)
[subject] 1 - 251 (271)
 1e-42 177   42%
Product
AlnR3 SARP family regulator
Gene
alnR3
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
41
 E4NBI0_KITSK
(E4NBI0)		 
[query] 1 - 248 (258)
[subject] 1 - 248 (269)
 2e-42 177   44%
Product
Putative AfsR family transcriptional regulator
Gene
KSE_27490
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
42
 Q83X33_STRRO
(Q83X33)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 2e-42 176   41%
Product
SARP family regulator SrrZ
Gene
srrZ
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
45
 F4FBT2_VERMA
(F4FBT2)		 
[query] 1 - 248 (258)
[subject] 2 - 245 (260)
 4e-42 176   40%
Product
SARP family transcriptional regulator
Gene
VAB18032_18150
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
46
 C7N0E0_SACVD
(C7N0E0)		 
[query] 1 - 248 (258)
[subject] 1 - 247 (631)
 6e-42 175   43%
Product
DNA-binding transcriptional activator of the SARP family
Gene
Svir_33780
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
47
 E2Q9D3_STRCL
(E2Q9D3)		 
[query] 1 - 249 (258)
[subject] 1 - 250 (278)
 7e-42 175   43%
Product
SARP family pathway specific regulatory protein
Gene
SCLAV_0477
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
48
 D9UBV4_STRPR
(D9UBV4)		 
[query] 1 - 249 (258)
[subject] 1 - 252 (285)
 1e-41 174   42%
Product
SARP-type regulator
Gene
papR1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
50
 E1ARL7_STRAU
(E1ARL7)		 
[query] 1 - 249 (258)
[subject] 1 - 251 (273)
 2e-41 173   41%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa35
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
51
 D9UBT4_STRPR
(D9UBT4)		 
[query] 18 - 248 (258)
[subject] 2 - 235 (258)
 2e-41 173   43%
Product
SARP-type regulator
Gene
cpp1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
53
 Q2L6C8_9ACTO
(Q2L6C8)		 
[query] 1 - 248 (258)
[subject] 71 - 320 (343)
 6e-41 172   40%
Product
Putative transcriptional regulator
Gene
 
Organism
Streptomyces sp. KO-3988
1uniprot[Pubmed] 16452404
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.(J. Bacteriol.) [2006]
55
 Q54494_STRNO
(Q54494)		 Jump to Nogl_00360 
[query] 1 - 249 (258)
[subject] 28 - 270 (665)
 1e-40 171   41%
Product
Snora
Gene
snorA
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
56
 O68913_9ACTO
(O68913)		 Jump to Fren_00070 
[query] 1 - 249 (258)
[subject] 1 - 252 (282)
 1e-40 171   42%
Product
Pathway specific regulator
Gene
frnG
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
57
 Q9LBV5_STRVG
(Q9LBV5)		 Jump to Virg_00290 
[query] 1 - 248 (258)
[subject] 1 - 251 (271)
 1e-40 171   42%
Product
Orf2
Gene
 
Organism
Streptomyces virginiae
1uniprot[Pubmed] 10792718 [Medline] 20253310
Identification of an AfsA homologue (BarX) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis, virginiamycin biosynthesis and virginiamycin M1 resistance.(Mol. Microbiol.) [2000]
58
 C9ZCB7_STRSW
(C9ZCB7)		 
[query] 1 - 249 (258)
[subject] 1 - 243 (919)
 2e-40 170   42%
Product
Putative transcriptional activator
Gene
SCAB_63021
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
59
 E2EKL8_9ACTO
(E2EKL8)		 
[query] 1 - 248 (258)
[subject] 2 - 252 (610)
 2e-40 170   41%
Product
Regulator
Gene
sanR1
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
61
 E1ARN0_STRAU
(E1ARN0)		 
[query] 1 - 248 (258)
[subject] 1 - 251 (272)
 2e-40 170   42%
Product
SARP family pathway specific regulatory protein
Gene
sa24
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
62
 Q8KSZ0_9ACTO
(Q8KSZ0)		 Jump to Griseo_00020 
[query] 1 - 249 (258)
[subject] 1 - 251 (273)
 3e-40 169   40%
Product
Putative transcriptional activator GrhR2
Gene
grhR2
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
63
 D9UBW9_STRPR
(D9UBW9)		 
[query] 1 - 248 (258)
[subject] 1 - 278 (300)
 4e-40 169   38%
Product
SARP-type regulator
Gene
papR4
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
64
 B5UAT1_STRLA
(B5UAT1)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 7e-40 168   40%
Product
SARP family regulator
Gene
farR3
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
65
 A7DWL6_STRTE
(A7DWL6)		 
[query] 1 - 248 (258)
[subject] 1 - 254 (613)
 7e-40 168   42%
Product
Putative transcriptional activator, SARP family
Gene
llpRIV
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
66
 Q83X29_STRRO
(Q83X29)		 
[query] 1 - 252 (258)
[subject] 1 - 262 (276)
 8e-40 168   40%
Product
SARP family regulator SrrY
Gene
srrY
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
67
 A2AXE3_STRCM
(A2AXE3)		 
[query] 1 - 248 (258)
[subject] 41 - 290 (313)
 9e-40 168   39%
Product
Putative SARP family pathway-specific regulator
Gene
fnq4
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
68
 Q6VMH5_STRAM
(Q6VMH5)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 9e-40 168   40%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
69
 Q1RQQ6_STRAM
(Q1RQQ6)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 9e-40 168   40%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
SAMT0179
SAMT0180
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
70
 Q0JW87_STRAM
(Q0JW87)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 1e-39 168   40%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0199
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
71
 E2D2K1_9BACT
(E2D2K1)		 
[query] 1 - 248 (258)
[subject] 6 - 255 (258)
 1e-39 167   38%
Product
Pathway specific transcriptional regulator
Gene
 
Organism
uncultured soil bacterium
1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]
72
 DNRI_STRPE
(P25047)		 Jump to Adria_00210 
[query] 1 - 248 (258)
[subject] 1 - 250 (272)
 3e-39 166   38%
Product
Regulatory protein dnrI
Gene
dnrI
Organism
Streptomyces peucetius
1uniprot[Pubmed] 1729206 [Medline] 92104954
Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius.(J. Bacteriol.) [1992]
74
 Q9KWX4_STRAM
(Q9KWX4)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (273)
 4e-39 166   40%
Product
Regulator (SAR)
Gene
sar
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 10628855 [Medline] 20092477
Cloning and characterization of a regulatory gene of the SARP family and its flanking region from Streptomyces ambofaciens.(Mol. Gen. Genet.) [1999]
75
 D2SZ12_MICEC
(D2SZ12)		 
[query] 1 - 249 (258)
[subject] 1 - 256 (293)
 5e-39 165   40%
Product
Transcriptional regulator
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
78
 Q8KSZ1_9ACTO
(Q8KSZ1)		 Jump to Griseo_00010 
[query] 1 - 257 (258)
[subject] 1 - 272 (273)
 2e-38 164   39%
Product
Putative transcriptional activator GrhR1
Gene
grhR1
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
79
 Q67G41_9ACTO
(Q67G41)		 Jump to Heda_00170 
[query] 1 - 248 (258)
[subject] 1 - 250 (272)
 2e-38 164   41%
Product
Putative regulatory protein
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
82
 B1GSM4_9ACTO
(B1GSM4)		 Jump to Bena_00140 
[query] 1 - 248 (258)
[subject] 7 - 252 (656)
 3e-38 163   42%
Product
BenR protein
Gene
benR
Organism
Streptomyces sp. A2991200
1uniprot[Pubmed] 17439117
Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007]
83
 E5DUG1_9NOCA
(E5DUG1)		 
[query] 1 - 248 (258)
[subject] 2 - 254 (299)
 4e-38 162   38%
Product
NocP
Gene
nocP
Organism
Nocardia sp. ATCC 202099
1uniprot[Pubmed] 20473441
Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.(Mol. Biosyst.) [2010]
84
 Q9KHL3_9ACTO
(Q9KHL3)		 Jump to Enter_00020 
[query] 1 - 249 (258)
[subject] 1 - 248 (283)
 1e-37 161   39%
Product
Putative transcriptional regulator EncF
Gene
encF
Organism
Streptomyces maritimus
1uniprot
Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000]
2uniprot[Pubmed] 11137817 [Medline] 20579517
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000]
3uniprot[Pubmed] 11948863 [Medline] 21942282
A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001]
[pubmed all]
86
 E2Q9B8_STRCL
(E2Q9B8)		 
[query] 1 - 249 (258)
[subject] 1 - 254 (931)
 1e-37 160   40%
Product
Putative regulatory protein AfsR-like protein
Gene
SCLAV_0462
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
87
 Q194R8_STRAA
(Q194R8)		 Jump to Mith_00020 
[query] 5 - 252 (258)
[subject] 3 - 251 (276)
 1e-37 160   40%
Product
Mithramycin regulator MtmR
Gene
mtmR
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 9882681 [Medline] 99102230
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.(J. Bacteriol.) [1999]
6uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
7uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
8uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
9uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
10uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
11uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
12uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
13uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
14uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
15uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
16uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
17uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
18uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
19uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
20uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
21uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
88
 C7PY63_CATAD
(C7PY63)		 
[query] 1 - 248 (258)
[subject] 1 - 250 (252)
 1e-37 160   38%
Product
Transcriptional regulator, SARP family
Gene
Caci_6503
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
89
 B0LJ06_9ACTO
(B0LJ06)		 
[query] 1 - 248 (258)
[subject] 1 - 248 (625)
 2e-37 160   41%
Product
Lct23
Gene
lct23
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
93
 F2RDR4_STRVP
(F2RDR4)		 
[query] 1 - 249 (258)
[subject] 5 - 255 (1018)
 5e-37 159   40%
Product
Putative uncharacterized protein SVEN_6270
Gene
SVEN_6270
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
94
 Q0RI37_FRAAA
(Q0RI37)		 
[query] 1 - 249 (258)
[subject] 4 - 251 (456)
 7e-37 158   40%
Product
Putative transcriptional regulator
Gene
FRAAL4193
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
95
 Q4R0M3_STRCX
(Q4R0M3)		 Jump to Chart_00090 
[query] 47 - 258 (258)
[subject] 1 - 215 (216)
 7e-37 158   42%
Product
ChaR1 protein
Gene
chaR1
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
99
 C9ZCD2_STRSW
(C9ZCD2)		 
[query] 1 - 249 (258)
[subject] 1 - 250 (278)
 3e-36 156   41%
Product
Putative regulatory protein
Gene
SCAB_63171
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]