BLAST table : Jado_00250

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q939Q5_9ACTO
(Q939Q5)		 
[query] 1 - 312 (312)
[subject] 1 - 312 (312)
 0.0 639   100% NDP-hexose 4,6-dehydratase jadT Streptomyces venezuelae
2
 F2RC33_STRVP
(F2RC33)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (322)
 1e-165 584   97% dTDP-glucose 4,6-dehydratase SVEN_5998 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) 4.2.1.46
3
 B8Y4F0_STRAU
(B8Y4F0)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (337)
 1e-132 474   75% dTDP-glucose 4,6-dehydratase aur1T Streptomyces aureofaciens 4.2.1.46
4
 A8M278_SALAI
(A8M278)		 
[query] 3 - 310 (312)
[subject] 13 - 325 (357)
 1e-131 471   73% dTDP-glucose 4,6-dehydratase Sare_2336 Salinispora arenicola (strain CNS-205) 4.2.1.46
5
 C4NYL8_9ACTO
(C4NYL8)		 
[query] 3 - 308 (312)
[subject] 13 - 318 (326)
 1e-129 465   74% dTDP-glucose 4,6-dehydratase saqH Micromonospora sp. Tu 6368 4.2.1.46
6
 Q7WT24_9ACTO
(Q7WT24)		 Jump to Medem_00180 
[query] 3 - 312 (312)
[subject] 13 - 322 (333)
 1e-129 464   72% dTDP-glucose 4,6-dehydratase med-ORF17 Streptomyces sp. AM-7161 4.2.1.46
7
 Q2HR54_9ACTO
(Q2HR54)		 Jump to Sch475_00260 
[query] 3 - 310 (312)
[subject] 13 - 320 (328)
 1e-128 462   72% dTDP-glucose 4,6-dehydratase schS5 Streptomyces sp. SCC 2136 4.2.1.46
8
 B1VRP9_STRGG
(B1VRP9)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (324)
 1e-126 454   70% dTDP-glucose 4,6-dehydratase SGR_638 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) 4.2.1.46
9
 Q9X5W0_STRGR
(Q9X5W0)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (324)
 1e-126 454   70% dTDP-glucose 4,6-dehydratase grsE Streptomyces griseus 4.2.1.46
10
 Q9ZGC7_STRCY
(Q9ZGC7)		 Jump to Lando_00130 
[query] 3 - 310 (312)
[subject] 14 - 321 (326)
 1e-125 453   72% dTDP-glucose 4,6-dehydratase lanH14 Streptomyces cyanogenus 4.2.1.46
11
 B0LJ31_9ACTO
(B0LJ31)		 
[query] 3 - 310 (312)
[subject] 13 - 320 (326)
 1e-123 445   72% dTDP-glucose 4,6-dehydratase lct48 Streptomyces rishiriensis 4.2.1.46
12
 D7BZT0_STRBB
(D7BZT0)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (322)
 1e-122 443   71% dTDP-glucose 4,6-dehydratase SBI_06865 Streptomyces bingchenggensis (strain BCW-1) 4.2.1.46
13
 Q2PC88_STRAH
(Q2PC88)		 Jump to Rubra_00020 
[query] 3 - 307 (312)
[subject] 13 - 317 (338)
 1e-121 441   73% dTDP-glucose 4,6-dehydratase rubN2 Streptomyces achromogenes subsp. rubradiris 4.2.1.46
14
 Q9RPA5_STRFR
(Q9RPA5)		 Jump to Urd_00220 
[query] 3 - 308 (312)
[subject] 13 - 318 (328)
 1e-121 439   71% dTDP-glucose 4,6-dehydratase urdH Streptomyces fradiae
Streptomyces roseoflavus		 4.2.1.46
15
 D9WEH5_9ACTO
(D9WEH5)		 
[query] 3 - 311 (312)
[subject] 13 - 321 (327)
 1e-119 432   68% dTDP-glucose 4,6-dehydratase SSOG_02928 Streptomyces himastatinicus ATCC 53653 4.2.1.46
16
 E3T495_9ACTO
(E3T495)		 
[query] 3 - 308 (312)
[subject] 13 - 318 (321)
 1e-117 424   67% dTDP-glucose 4,6-dehydratase gra-orf17 Streptomyces vietnamensis 4.2.1.46
17
 D1A6U0_THECD
(D1A6U0)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (336)
 1e-116 422   65% dTDP-glucose 4,6-dehydratase Tcur_2799 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081) 4.2.1.46
18
 B5GLJ1_STRCL
(B5GLJ1)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (324)
 1e-115 419   65% dTDP-glucose 4,6-dehydratase SCLAV_p1371
SSCG_00215		 Streptomyces clavuligerus ATCC 27064 4.2.1.46
19
 Q8RS23_STRVL
(Q8RS23)		 
[query] 3 - 311 (312)
[subject] 13 - 321 (327)
 1e-113 414   66% dTDP-glucose 4,6-dehydratase rhoH Streptomyces violaceus
Streptomyces venezuelae		 4.2.1.46
20
 Q2PZR3_9ACTO
(Q2PZR3)		 Jump to Cosmo_00130 
[query] 3 - 311 (312)
[subject] 13 - 321 (327)
 1e-113 413   66% dTDP-glucose 4,6-dehydratase cosH Streptomyces olindensis 4.2.1.46
21
 Q70J87_STRGR
(Q70J87)		 Jump to Chro_00110 
[query] 3 - 307 (312)
[subject] 13 - 316 (326)
 1e-110 404   65% dTDP-glucose 4,6-dehydratase cmmE Streptomyces griseus subsp. griseus 4.2.1.46
22
 B5G8A3_9ACTO
(B5G8A3)		 
[query] 3 - 303 (312)
[subject] 10 - 310 (328)
 1e-110 403   68% dTDP-glucose 4,6-dehydratase SSBG_00511 Streptomyces sp. SPB74 4.2.1.46
23
 Q56173_STRVN
(Q56173)		 Jump to Grana_00110 
[query] 3 - 308 (312)
[subject] 13 - 318 (321)
 1e-110 402   65% dTDP-glucose 4,6-dehydratase graE
gra-orf17		 Streptomyces violaceoruber 4.2.1.46
24
 Q0R4N2_STRAT
(Q0R4N2)		 Jump to Chth_00220 
[query] 3 - 312 (312)
[subject] 13 - 322 (327)
 1e-110 401   65% dTDP-glucose 4,6-dehydratase Streptomyces antibioticus 4.2.1.46
25
 Q9L4U7_9ACTO
(Q9L4U7)		 Jump to Acla_00200 
[query] 3 - 301 (312)
[subject] 13 - 311 (323)
 1e-109 400   68% dTDP-glucose 4,6-dehydratase aknR Streptomyces galilaeus 4.2.1.46
26
 Q9F5R6_STRSD
(Q9F5R6)		 
[query] 3 - 312 (312)
[subject] 13 - 326 (332)
 1e-109 400   64% dTDP-glucose 4,6-dehydratase Streptomyces sp. (strain ATCC 17920 / DSM 40477 / NCIB 11028)
Streptomyces tenebrarius		 4.2.1.46
27
 A0ACJ2_STRAM
(A0ACJ2)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 1e-108 395   63% dTDP-glucose 4,6-dehydratase SAMR0486 Streptomyces ambofaciens ATCC 23877 4.2.1.46
28
 D7RFL0_AMYOR
(D7RFL0)		 
[query] 3 - 306 (312)
[subject] 14 - 317 (327)
 1e-107 394   66% dTDP-glucose 4,6-dehydratase bexS Amycolatopsis orientalis subsp. vinearia 4.2.1.46
29
 Q83X80_STRRO
(Q83X80)		 
[query] 3 - 307 (312)
[subject] 13 - 318 (328)
 1e-106 388   64% dTDP-glucose 4,6-dehydratase lkmD Streptomyces rochei
Streptomyces parvullus		 4.2.1.46
30
 E0L0G4_STRVO
(E0L0G4)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (324)
 1e-106 388   63% dTDP-glucose 4,6-dehydratase StrviDRAFT_8392 Streptomyces violaceusniger Tu 4113 4.2.1.46
31
 E9L1H3_9ZZZZ
(E9L1H3)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (326)
 1e-105 386   62% Putative uncharacterized protein CA37-29 uncultured organism CA37
32
 Q83WD7_MICGR
(Q83WD7)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (342)
 1e-105 384   63% dTDP-glucose 4,6-dehydratase mydB Micromonospora griseorubida 4.2.1.46
33
 D9I0H4_9ACTO
(D9I0H4)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (326)
 1e-104 382   62% dTDP-glucose 4,6-dehydratase cpzDIII Streptomyces sp. MK730-62F2 4.2.1.46
34
 D8I3S0_AMYMU
(D8I3S0)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (329)
 1e-104 382   64% dTDP-glucose 4,6-dehydratase rfbB
AMED_1007		 Amycolatopsis mediterranei (strain U-32) 4.2.1.46
35
 A1YZ53_9ACTO
(A1YZ53)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (330)
 1e-104 382   62% dTDP-glucose 4,6-dehydratase pdmY Actinomadura hibisca 4.2.1.46
36
 A0LRX9_ACIC1
(A0LRX9)		 
[query] 3 - 312 (312)
[subject] 9 - 319 (324)
 1e-104 381   60% dTDP-glucose 4,6-dehydratase Acel_0415 Acidothermus cellulolyticus (strain ATCC 43068 / 11B) 4.2.1.46
37
 C7MUW7_SACVD
(C7MUW7)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (330)
 1e-104 381   62% dTDP-glucose 4,6-dehydratase Svir_06090 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) 4.2.1.46
38
 C6WJ73_ACTMD
(C6WJ73)		 
[query] 3 - 312 (312)
[subject] 13 - 325 (330)
 1e-103 378   61% dTDP-glucose 4,6-dehydratase Amir_6347 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) 4.2.1.46
39
 D9V6R3_9ACTO
(D9V6R3)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (330)
 1e-102 377   62% dTDP-glucose 4,6-dehydratase SSMG_00677 Streptomyces sp. AA4 4.2.1.46
40
 A4X723_SALTO
(A4X723)		 
[query] 3 - 306 (312)
[subject] 13 - 316 (335)
 1e-102 376   65% dTDP-glucose 4,6-dehydratase Strop_2222 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) 4.2.1.46
41
 Q9ZGH3_9ACTO
(Q9ZGH3)		 Jump to Pikro_00130 
[query] 3 - 307 (312)
[subject] 13 - 319 (337)
 1e-102 376   65% dTDP-glucose 4,6-dehydratase desIV Streptomyces venezuelae 4.2.1.46
42
 D9XDA8_STRVR
(D9XDA8)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (326)
 1e-102 375   62% dTDP-glucose 4,6-dehydratase SSQG_07273 Streptomyces viridochromogenes DSM 40736 4.2.1.46
43
 E5F142_9ACTO
(E5F142)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (324)
 1e-102 375   60% dTDP-glucose 4,6-dehydratase rmlB Kitasatospora kifunensis 4.2.1.46
44
 Q9S0P5_STRAW
(Q9S0P5)		 Jump to Aver_00120 
[query] 3 - 307 (312)
[subject] 9 - 315 (355)
 1e-102 374   63% dTDP-glucose 4,6-dehydratase aveBII
SAV946
SAV_946		 Streptomyces avermitilis 4.2.1.46
45
 B3TMR2_9ACTO
(B3TMR2)		 
[query] 3 - 312 (312)
[subject] 17 - 328 (342)
 1e-102 374   60% dTDP-glucose 4,6-dehydratase KijD4 Actinomadura kijaniata 4.2.1.46
46
 B5L6K3_MICCH
(B5L6K3)		 
[query] 3 - 307 (312)
[subject] 17 - 323 (332)
 1e-101 372   62% dTDP-glucose 4,6-dehydratase Micromonospora chalcea 4.2.1.46
47
 Q8KRX3_9ACTO
(Q8KRX3)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (344)
 1e-101 372   63% dTDP-glucose 4,6-dehydratase nbmH Streptomyces narbonensis 4.2.1.46
48
 C4RP68_9ACTO
(C4RP68)		 
[query] 3 - 312 (312)
[subject] 15 - 323 (330)
 1e-101 372   60% dTDP-glucose 4,6-dehydratase MCAG_03631 Micromonospora sp. ATCC 39149 4.2.1.46
49
 D9TDA3_MICAI
(D9TDA3)		 
[query] 3 - 310 (312)
[subject] 13 - 328 (333)
 1e-100 370   61% dTDP-glucose 4,6-dehydratase Micau_1179 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) 4.2.1.46
50
 B5HXA7_9ACTO
(B5HXA7)		 
[query] 3 - 312 (312)
[subject] 15 - 325 (328)
 1e-100 370   60% dTDP-glucose 4,6-dehydratase SSEG_09375 Streptomyces sviceus ATCC 29083 4.2.1.46
51
 A8KQL1_9ACTO
(A8KQL1)		 Jump to Ello_00270 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 1e-100 369   61% dTDP-glucose 4,6-dehydratase rhaB Streptomyces olivaceus 4.2.1.46
52
 E8S5H3_MICSL
(E8S5H3)		 
[query] 3 - 307 (312)
[subject] 13 - 325 (333)
 1e-100 369   61% dTDP-glucose 4,6-dehydratase ML5_1442 Micromonospora sp. (strain L5) 4.2.1.46
53
 D6A3M1_9ACTO
(D6A3M1)		 
[query] 3 - 312 (312)
[subject] 39 - 349 (353)
 1e-100 368   59% dTDP-glucose 4,6-dehydratase SSFG_04776 Streptomyces ghanaensis ATCC 14672 4.2.1.46
54
 D2SG25_GEOOG
(D2SG25)		 
[query] 3 - 307 (312)
[subject] 13 - 320 (331)
 1e-100 367   62% dTDP-glucose 4,6-dehydratase Gobs_4331 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) 4.2.1.46
55
 Q54144_STRFR
(Q54144)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (333)
 1e-99 367   61% dTDP-glucose 4,6-dehydratase Streptomyces fradiae
Streptomyces roseoflavus		 4.2.1.46
56
 D9UBQ9_STRPR
(D9UBQ9)		 
[query] 3 - 312 (312)
[subject] 15 - 324 (335)
 1e-99 367   62% dTDP-glucose 4,6-dehydratase cpp25 Streptomyces pristinaespiralis 4.2.1.46
57
 B5HIU1_STRPR
(B5HIU1)		 
[query] 3 - 312 (312)
[subject] 15 - 324 (335)
 1e-99 367   62% dTDP-glucose 4,6-dehydratase SSDG_05078 Streptomyces pristinaespiralis ATCC 25486 4.2.1.46
58
 B5H782_STRPR
(B5H782)		 
[query] 3 - 312 (312)
[subject] 15 - 325 (328)
 1e-99 367   60% dTDP-glucose 4,6-dehydratase SSDG_01263 Streptomyces pristinaespiralis ATCC 25486 4.2.1.46
59
 Q9KK63_STRRY
(Q9KK63)		 
[query] 3 - 307 (312)
[subject] 13 - 316 (317)
 2e-99 367   61% DTDP-glucose 4,6-dehydratase prmE Streptomyces rimosus subsp. paromomycinus
60
 Q9RN58_STRNO
(Q9RN58)		 Jump to Nogl_00210 
[query] 3 - 310 (312)
[subject] 23 - 333 (350)
 3e-99 365   62% dTDP-glucose 4,6-dehydratase snogK Streptomyces nogalater 4.2.1.46
61
 A4FNM4_SACEN
(A4FNM4)		 
[query] 3 - 310 (312)
[subject] 13 - 322 (329)
 4e-99 365   59% dTDP-glucose 4,6-dehydratase aveBII
SACE_6480		 Saccharopolyspora erythraea (strain NRRL 23338) 4.2.1.46
62
 Q54116_SACER
(Q54116)		 
[query] 3 - 310 (312)
[subject] 13 - 322 (329)
 4e-99 365   59% dTDP-glucose 4,6-dehydratase gdh Saccharopolyspora erythraea
Streptomyces erythraeus		 4.2.1.46
63
 D9Y1L8_9ACTO
(D9Y1L8)		 
[query] 3 - 312 (312)
[subject] 23 - 333 (337)
 5e-99 365   60% dTDP-glucose 4,6-dehydratase SSRG_04187 Streptomyces griseoflavus Tu4000 4.2.1.46
64
 D6AXP0_9ACTO
(D6AXP0)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (331)
 5e-99 365   61% dTDP-glucose 4,6-dehydratase SSHG_05332 Streptomyces albus J1074 4.2.1.46
65
 E4N8V2_KITSK
(E4N8V2)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (330)
 8e-99 364   62% dTDP-glucose 4,6-dehydratase rmlB2
KSE_18080		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae		 4.2.1.46
66
 E1CG47_9ACTO
(E1CG47)		 
[query] 3 - 307 (312)
[subject] 13 - 316 (321)
 9e-99 364   61% dTDP-glucose 4,6-dehydratase capQ Streptomyces sp. SANK 62799 4.2.1.46
67
 C5J046_STRPE
(C5J046)		 
[query] 3 - 312 (312)
[subject] 15 - 325 (328)
 1e-98 364   59% dTDP-glucose 4,6-dehydratase rmbB Streptomyces peucetius ATCC 27952 4.2.1.46
68
 F4F6Y4_VERMA
(F4F6Y4)		 
[query] 3 - 307 (312)
[subject] 13 - 325 (333)
 2e-98 363   61% dTDP-glucose 4,6-dehydratase VAB18032_22795 Verrucosispora maris (strain AB-18-032) 4.2.1.46
69
 Q93EK0_9PSEU
(Q93EK0)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 3e-98 363   59% dTDP-glucose 4,6-dehydratase gdh Saccharopolyspora spinosa 4.2.1.46
70
 Q9RMG0_STRGL
(Q9RMG0)		 Jump to C1027_00240 
[query] 3 - 311 (312)
[subject] 13 - 323 (332)
 3e-98 363   59% dTDP-glucose 4,6-dehydratase sgcA Streptomyces globisporus 4.2.1.46
71
 A4AI60_9ACTN
(A4AI60)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (327)
 3e-98 363   60% dTDP-glucose 4,6-dehydratase A20C1_06126 marine actinobacterium PHSC20C1 4.2.1.46
72
 D2B1Y0_STRRD
(D2B1Y0)		 
[query] 3 - 307 (312)
[subject] 13 - 318 (325)
 3e-98 362   60% dTDP-glucose 4,6-dehydratase Sros_6490 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) 4.2.1.46
73
 Q76KZ7_STRHA
(Q76KZ7)		 Jump to Vicen_00030 
[query] 3 - 310 (312)
[subject] 15 - 317 (323)
 4e-98 362   61% dTDP-glucose 4,6-dehydratase vinB Streptomyces halstedii 4.2.1.46
74
 D1XFK5_9ACTO
(D1XFK5)		 
[query] 3 - 312 (312)
[subject] 15 - 325 (328)
 4e-98 362   59% dTDP-glucose 4,6-dehydratase SACTEDRAFT_1465 Streptomyces sp. SA3_actE 4.2.1.46
75
 Q194R3_STRAA
(Q194R3)		 Jump to Mith_00070 
[query] 3 - 307 (312)
[subject] 16 - 320 (331)
 6e-98 362   62% dTDP-glucose 4,6-dehydratase mtmE Streptomyces argillaceus 4.2.1.46
76
 Q5SFD3_STRBI
(Q5SFD3)		 Jump to Chalc_00110 
[query] 3 - 308 (312)
[subject] 13 - 320 (323)
 8e-98 361   60% dTDP-glucose 4,6-dehydratase chmAII Streptomyces bikiniensis 4.2.1.46
77
 E4NCQ6_KITSK
(E4NCQ6)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (325)
 9e-98 361   58% dTDP-glucose 4,6-dehydratase rmlB1
KSE_31770		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae		 4.2.1.46
78
 D2B4G9_STRRD
(D2B4G9)		 
[query] 3 - 308 (312)
[subject] 13 - 309 (340)
 2e-97 360   60% dTDP-glucose 4,6-dehydratase Sros_0632 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) 4.2.1.46
79
 F8K053_STRCT
(F8K053)		 
[query] 3 - 307 (312)
[subject] 18 - 322 (328)
 2e-97 360   61% dTDP-glucose 4,6-dehydratase strE
SCAT_2478		 Streptomyces cattleya 4.2.1.46
80
 B4VAI6_9ACTO
(B4VAI6)		 
[query] 3 - 310 (312)
[subject] 13 - 322 (323)
 3e-97 359   60% dTDP-glucose 4,6-dehydratase SSAG_04825 Streptomyces sp. Mg1 4.2.1.46
81
 Q3S887_9ACTO
(Q3S887)		 Jump to Conca_00140 
[query] 3 - 312 (312)
[subject] 13 - 323 (326)
 4e-97 359   60% dTDP-glucose 4,6-dehydratase Streptomyces neyagawaensis 4.2.1.46
82
 D1H0B0_9ACTO
(D1H0B0)		 
[query] 3 - 312 (312)
[subject] 16 - 325 (328)
 6e-97 358   60% dTDP-glucose 4,6-dehydratase chryE Streptomyces albaduncus 4.2.1.46
83
 A0ADF0_STRAM
(A0ADF0)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (348)
 8e-97 358   61% dTDP-glucose 4,6-dehydratase SAMR0797 Streptomyces ambofaciens ATCC 23877 4.2.1.46
84
 Q331R3_9ACTO
(Q331R3)		 
[query] 3 - 310 (312)
[subject] 10 - 319 (320)
 2e-96 357   60% dTDP-glucose 4,6-dehydratase gerE Streptomyces sp. KCTC 0041BP 4.2.1.46
85
 Q7WTE5_9ACTO
(Q7WTE5)		 Jump to Nanch_00180 
[query] 3 - 307 (312)
[subject] 13 - 319 (331)
 2e-96 357   60% dTDP-glucose 4,6-dehydratase nanG2 Streptomyces nanchangensis 4.2.1.46
86
 F4CKA6_9PSEU
(F4CKA6)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (324)
 2e-96 357   60% dTDP-glucose 4,6-dehydratase Psed_0177 Pseudonocardia dioxanivorans CB1190 4.2.1.46
87
 Q9RJE3_STRCO
(Q9RJE3)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (324)
 2e-96 357   61% dTDP-glucose 4,6-dehydratase SCO0749 Streptomyces coelicolor 4.2.1.46
88
 D6EYD0_STRLI
(D6EYD0)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (324)
 2e-96 357   61% dTDP-glucose 4,6-dehydratase SSPG_06849 Streptomyces lividans TK24 4.2.1.46
89
 A5CPQ0_CLAM3
(A5CPQ0)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 3e-96 356   60% dTDP-glucose 4,6-dehydratase rmlB
CMM_1010		 Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) 4.2.1.46
90
 D7BSN0_STRBB
(D7BSN0)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (331)
 3e-96 356   60% dTDP-glucose 4,6-dehydratase nanG2
SBI_08409		 Streptomyces bingchenggensis (strain BCW-1) 4.2.1.46
91
 C7G1T6_STRGR
(C7G1T6)		 
[query] 3 - 307 (312)
[subject] 13 - 316 (321)
 4e-96 355   60% dTDP-glucose 4,6-dehydratase Streptomyces griseus 4.2.1.46
92
 B0RDV6_CLAMS
(B0RDV6)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 5e-96 355   59% dTDP-glucose 4,6-dehydratase CMS0629 Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) 4.2.1.46
93
 C9YYJ5_STRSW
(C9YYJ5)		 
[query] 3 - 312 (312)
[subject] 13 - 323 (326)
 7e-96 355   59% dTDP-glucose 4,6-dehydratase SCAB_84041 Streptomyces scabies (strain 87.22)
Streptomyces scabiei		 4.2.1.46
94
 A8CAC2_9ACTO
(A8CAC2)		 
[query] 3 - 311 (312)
[subject] 13 - 323 (332)
 7e-96 355   59% dTDP-glucose 4,6-dehydratase Streptomyces eurythermus 4.2.1.46
95
 B5H2M7_STRCL
(B5H2M7)		 
[query] 3 - 311 (312)
[subject] 13 - 313 (324)
 1e-95 354   60% dTDP-glucose 4,6-dehydratase staB
SCLAV_p1121
SSCG_05850		 Streptomyces clavuligerus ATCC 27064 4.2.1.46
96
 C0JWC1_9ACTO
(C0JWC1)		 Jump to Polk_00260 
[query] 3 - 305 (312)
[subject] 16 - 315 (329)
 1e-95 354   59% dTDP-glucose 4,6-dehydratase pokS2 Streptomyces diastatochromogenes 4.2.1.46
97
 Q2I756_9ACTO
(Q2I756)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (323)
 1e-95 354   61% dTDP-glucose 4,6-dehydratase plaA3
STTU_1455		 Streptomyces sp. Tu6071 4.2.1.46
98
 C8XIN5_NAKMY
(C8XIN5)		 
[query] 3 - 312 (312)
[subject] 13 - 326 (331)
 3e-95 353   57% dTDP-glucose 4,6-dehydratase Namu_4211 Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104)
Microsphaera multipartita		 4.2.1.46
99
 Q9L6C3_STRAT
(Q9L6C3)		 
[query] 3 - 311 (312)
[subject] 13 - 321 (335)
 4e-95 352   60% dTDP-glucose 4,6-dehydratase Streptomyces antibioticus 4.2.1.46
100
 C7QIW6_CATAD
(C7QIW6)		 
[query] 3 - 312 (312)
[subject] 13 - 321 (338)
 1e-94 350   58% dTDP-glucose 4,6-dehydratase Caci_8193 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) 4.2.1.46
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q939Q5_9ACTO
(Q939Q5)		 
[query] 1 - 312 (312)
[subject] 1 - 312 (312)
 0.0 639   100%
Product
NDP-hexose 4,6-dehydratase
Gene
jadT
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 11932454 [Medline] 21930291
Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone.(Microbiology) [2002]
2
 F2RC33_STRVP
(F2RC33)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (322)
 1e-165 584   97%
Product
dTDP-glucose 4,6-dehydratase
Gene
SVEN_5998
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
3
 B8Y4F0_STRAU
(B8Y4F0)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (337)
 1e-132 474   75%
Product
dTDP-glucose 4,6-dehydratase
Gene
aur1T
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 20490753
Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.(Folia Microbiol. (Praha)) [2010]
5
 C4NYL8_9ACTO
(C4NYL8)		 
[query] 3 - 308 (312)
[subject] 13 - 318 (326)
 1e-129 465   74%
Product
dTDP-glucose 4,6-dehydratase
Gene
saqH
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
6
 Q7WT24_9ACTO
(Q7WT24)		 Jump to Medem_00180 
[query] 3 - 312 (312)
[subject] 13 - 322 (333)
 1e-129 464   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
med-ORF17
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
7
 Q2HR54_9ACTO
(Q2HR54)		 Jump to Sch475_00260 
[query] 3 - 310 (312)
[subject] 13 - 320 (328)
 1e-128 462   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
schS5
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
8
 B1VRP9_STRGG
(B1VRP9)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (324)
 1e-126 454   70%
Product
dTDP-glucose 4,6-dehydratase
Gene
SGR_638
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
10
 Q9ZGC7_STRCY
(Q9ZGC7)		 Jump to Lando_00130 
[query] 3 - 310 (312)
[subject] 14 - 321 (326)
 1e-125 453   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
lanH14
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
11
 B0LJ31_9ACTO
(B0LJ31)		 
[query] 3 - 310 (312)
[subject] 13 - 320 (326)
 1e-123 445   72%
Product
dTDP-glucose 4,6-dehydratase
Gene
lct48
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
12
 D7BZT0_STRBB
(D7BZT0)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (322)
 1e-122 443   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
SBI_06865
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
13
 Q2PC88_STRAH
(Q2PC88)		 Jump to Rubra_00020 
[query] 3 - 307 (312)
[subject] 13 - 317 (338)
 1e-121 441   73%
Product
dTDP-glucose 4,6-dehydratase
Gene
rubN2
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
14
 Q9RPA5_STRFR
(Q9RPA5)		 Jump to Urd_00220 
[query] 3 - 308 (312)
[subject] 13 - 318 (328)
 1e-121 439   71%
Product
dTDP-glucose 4,6-dehydratase
Gene
urdH
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
17
 D1A6U0_THECD
(D1A6U0)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (336)
 1e-116 422   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
Tcur_2799
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
18
 B5GLJ1_STRCL
(B5GLJ1)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (324)
 1e-115 419   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
SCLAV_p1371
SSCG_00215
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
20
 Q2PZR3_9ACTO
(Q2PZR3)		 Jump to Cosmo_00130 
[query] 3 - 311 (312)
[subject] 13 - 321 (327)
 1e-113 413   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
cosH
Organism
Streptomyces olindensis
1uniprot[Pubmed] 16810496
Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.(Appl. Microbiol. Biotechnol.) [2006]
23
 Q56173_STRVN
(Q56173)		 Jump to Grana_00110 
[query] 3 - 308 (312)
[subject] 13 - 318 (321)
 1e-110 402   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
graE
gra-orf17
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
2uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
24
 Q0R4N2_STRAT
(Q0R4N2)		 Jump to Chth_00220 
[query] 3 - 312 (312)
[subject] 13 - 322 (327)
 1e-110 401   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
25
 Q9L4U7_9ACTO
(Q9L4U7)		 Jump to Acla_00200 
[query] 3 - 301 (312)
[subject] 13 - 311 (323)
 1e-109 400   68%
Product
dTDP-glucose 4,6-dehydratase
Gene
aknR
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 11016846 [Medline] 20469061
A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000]
26
 Q9F5R6_STRSD
(Q9F5R6)		 
[query] 3 - 312 (312)
[subject] 13 - 326 (332)
 1e-109 400   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces sp. (strain ATCC 17920 / DSM 40477 / NCIB 11028)
Streptomyces tenebrarius
1uniprot[Pubmed] 11517612 [Medline] 21409420
Cloning of the sugar related biosynthesis gene cluster from Streptomyces tenebrarius H6(Sheng Wu Gong Cheng Xue Bao) [2001]
27
 A0ACJ2_STRAM
(A0ACJ2)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 1e-108 395   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
SAMR0486
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
28
 D7RFL0_AMYOR
(D7RFL0)		 
[query] 3 - 306 (312)
[subject] 14 - 317 (327)
 1e-107 394   66%
Product
dTDP-glucose 4,6-dehydratase
Gene
bexS
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
29
 Q83X80_STRRO
(Q83X80)		 
[query] 3 - 307 (312)
[subject] 13 - 318 (328)
 1e-106 388   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
lkmD
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
31
 E9L1H3_9ZZZZ
(E9L1H3)		 
[query] 3 - 312 (312)
[subject] 13 - 322 (326)
 1e-105 386   62%
Product
Putative uncharacterized protein
Gene
CA37-29
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
32
 Q83WD7_MICGR
(Q83WD7)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (342)
 1e-105 384   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
mydB
Organism
Micromonospora griseorubida
1uniprot[Pubmed] 12583909 [Medline] 22472038
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
33
 D9I0H4_9ACTO
(D9I0H4)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (326)
 1e-104 382   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
cpzDIII
Organism
Streptomyces sp. MK730-62F2
1uniprot[Pubmed] 20418426
Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.(Appl. Environ. Microbiol.) [2010]
34
 D8I3S0_AMYMU
(D8I3S0)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (329)
 1e-104 382   64%
Product
dTDP-glucose 4,6-dehydratase
Gene
rfbB
AMED_1007
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
37
 C7MUW7_SACVD
(C7MUW7)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (330)
 1e-104 381   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
Svir_06090
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
38
 C6WJ73_ACTMD
(C6WJ73)		 
[query] 3 - 312 (312)
[subject] 13 - 325 (330)
 1e-103 378   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
Amir_6347
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
41
 Q9ZGH3_9ACTO
(Q9ZGH3)		 Jump to Pikro_00130 
[query] 3 - 307 (312)
[subject] 13 - 319 (337)
 1e-102 376   65%
Product
dTDP-glucose 4,6-dehydratase
Gene
desIV
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
2uniprot[Pubmed] 14570895
High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae.(J. Biol. Chem.) [2004]
[pubmed all]
43
 E5F142_9ACTO
(E5F142)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (324)
 1e-102 375   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB
Organism
Kitasatospora kifunensis
1uniprot[Pubmed] 20667525
Cloning and in vitro characterization of dTDP-6-deoxy-L-talose biosynthetic genes from Kitasatospora kifunensis featuring the dTDP-6-deoxy-L-lyxo-4-hexulose reductase that synthesizes dTDP-6-deoxy-L-talose.(Carbohydr. Res.) [2010]
44
 Q9S0P5_STRAW
(Q9S0P5)		 Jump to Aver_00120 
[query] 3 - 307 (312)
[subject] 9 - 315 (355)
 1e-102 374   63%
Product
dTDP-glucose 4,6-dehydratase
Gene
aveBII
SAV946
SAV_946
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
45
 B3TMR2_9ACTO
(B3TMR2)		 
[query] 3 - 312 (312)
[subject] 17 - 328 (342)
 1e-102 374   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
KijD4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
46
 B5L6K3_MICCH
(B5L6K3)		 
[query] 3 - 307 (312)
[subject] 17 - 323 (332)
 1e-101 372   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
51
 A8KQL1_9ACTO
(A8KQL1)		 Jump to Ello_00270 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 1e-100 369   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
rhaB
Organism
Streptomyces olivaceus
1uniprot[Pubmed] 18310024
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008]
55
 Q54144_STRFR
(Q54144)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (333)
 1e-99 367   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7984112 [Medline] 95075319
Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome.(Mol. Microbiol.) [1994]
56
 D9UBQ9_STRPR
(D9UBQ9)		 
[query] 3 - 312 (312)
[subject] 15 - 324 (335)
 1e-99 367   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
cpp25
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
60
 Q9RN58_STRNO
(Q9RN58)		 Jump to Nogl_00210 
[query] 3 - 310 (312)
[subject] 23 - 333 (350)
 3e-99 365   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
snogK
Organism
Streptomyces nogalater
1uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
2uniprot[Pubmed] 10639368 [Medline] 20106987
Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000]
[pubmed all]
61
 A4FNM4_SACEN
(A4FNM4)		 
[query] 3 - 310 (312)
[subject] 13 - 322 (329)
 4e-99 365   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
aveBII
SACE_6480
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
62
 Q54116_SACER
(Q54116)		 
[query] 3 - 310 (312)
[subject] 13 - 322 (329)
 4e-99 365   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
gdh
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 7883182 [Medline] 95189100
Cloning of the genes encoding thymidine diphosphoglucose 4,6-dehydratase and thymidine diphospho-4-keto-6-deoxyglucose 3,5-epimerase from the erythromycin-producing Saccharopolyspora erythraea.(Gene) [1995]
65
 E4N8V2_KITSK
(E4N8V2)		 
[query] 3 - 307 (312)
[subject] 13 - 317 (330)
 8e-99 364   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB2
KSE_18080
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
68
 F4F6Y4_VERMA
(F4F6Y4)		 
[query] 3 - 307 (312)
[subject] 13 - 325 (333)
 2e-98 363   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
VAB18032_22795
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
69
 Q93EK0_9PSEU
(Q93EK0)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 3e-98 363   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
gdh
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11544225 [Medline] 21429236
Rhamnose biosynthesis pathway supplies precursors for primary and secondary metabolism in Saccharopolyspora spinosa.(J. Bacteriol.) [2001]
70
 Q9RMG0_STRGL
(Q9RMG0)		 Jump to C1027_00240 
[query] 3 - 311 (312)
[subject] 13 - 323 (332)
 3e-98 363   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
sgcA
Organism
Streptomyces globisporus
1uniprot[Pubmed] 10639366 [Medline] 20106985
Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.(Antimicrob. Agents Chemother.) [2000]
2uniprot[Pubmed] 12183628 [Medline] 22171413
Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002]
[pubmed all]
72
 D2B1Y0_STRRD
(D2B1Y0)		 
[query] 3 - 307 (312)
[subject] 13 - 318 (325)
 3e-98 362   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
Sros_6490
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
73
 Q76KZ7_STRHA
(Q76KZ7)		 Jump to Vicen_00030 
[query] 3 - 310 (312)
[subject] 15 - 317 (323)
 4e-98 362   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
vinB
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
75
 Q194R3_STRAA
(Q194R3)		 Jump to Mith_00070 
[query] 3 - 307 (312)
[subject] 16 - 320 (331)
 6e-98 362   62%
Product
dTDP-glucose 4,6-dehydratase
Gene
mtmE
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
76
 Q5SFD3_STRBI
(Q5SFD3)		 Jump to Chalc_00110 
[query] 3 - 308 (312)
[subject] 13 - 320 (323)
 8e-98 361   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
chmAII
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
77
 E4NCQ6_KITSK
(E4NCQ6)		 
[query] 3 - 312 (312)
[subject] 13 - 320 (325)
 9e-98 361   58%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB1
KSE_31770
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
78
 D2B4G9_STRRD
(D2B4G9)		 
[query] 3 - 308 (312)
[subject] 13 - 309 (340)
 2e-97 360   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
Sros_0632
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
81
 Q3S887_9ACTO
(Q3S887)		 Jump to Conca_00140 
[query] 3 - 312 (312)
[subject] 13 - 323 (326)
 4e-97 359   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
83
 A0ADF0_STRAM
(A0ADF0)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (348)
 8e-97 358   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
SAMR0797
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
84
 Q331R3_9ACTO
(Q331R3)		 
[query] 3 - 310 (312)
[subject] 10 - 319 (320)
 2e-96 357   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
gerE
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
85
 Q7WTE5_9ACTO
(Q7WTE5)		 Jump to Nanch_00180 
[query] 3 - 307 (312)
[subject] 13 - 319 (331)
 2e-96 357   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
nanG2
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
87
 Q9RJE3_STRCO
(Q9RJE3)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (324)
 2e-96 357   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
SCO0749
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
89
 A5CPQ0_CLAM3
(A5CPQ0)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 3e-96 356   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
rmlB
CMM_1010
Organism
Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
1uniprot[Pubmed] 18192381
The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity.(J. Bacteriol.) [2008]
90
 D7BSN0_STRBB
(D7BSN0)		 
[query] 3 - 307 (312)
[subject] 13 - 319 (331)
 3e-96 356   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
nanG2
SBI_08409
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
91
 C7G1T6_STRGR
(C7G1T6)		 
[query] 3 - 307 (312)
[subject] 13 - 316 (321)
 4e-96 355   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces griseus
1uniprot
Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196.(J. Antibiot.) [2009]
92
 B0RDV6_CLAMS
(B0RDV6)		 
[query] 3 - 312 (312)
[subject] 13 - 324 (329)
 5e-96 355   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
CMS0629
Organism
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667)
1uniprot[Pubmed] 18192393
Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation.(J. Bacteriol.) [2008]
93
 C9YYJ5_STRSW
(C9YYJ5)		 
[query] 3 - 312 (312)
[subject] 13 - 323 (326)
 7e-96 355   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
SCAB_84041
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
95
 B5H2M7_STRCL
(B5H2M7)		 
[query] 3 - 311 (312)
[subject] 13 - 313 (324)
 1e-95 354   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
staB
SCLAV_p1121
SSCG_05850
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
96
 C0JWC1_9ACTO
(C0JWC1)		 Jump to Polk_00260 
[query] 3 - 305 (312)
[subject] 16 - 315 (329)
 1e-95 354   59%
Product
dTDP-glucose 4,6-dehydratase
Gene
pokS2
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
97
 Q2I756_9ACTO
(Q2I756)		 
[query] 3 - 307 (312)
[subject] 13 - 315 (323)
 1e-95 354   61%
Product
dTDP-glucose 4,6-dehydratase
Gene
plaA3
STTU_1455
Organism
Streptomyces sp. Tu6071
1uniprot[Pubmed] 16632249
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives.(Chem. Biol.) [2006]
99
 Q9L6C3_STRAT
(Q9L6C3)		 
[query] 3 - 311 (312)
[subject] 13 - 321 (335)
 4e-95 352   60%
Product
dTDP-glucose 4,6-dehydratase
Gene
 
Organism
Streptomyces antibioticus
1uniprot
Mechanism of the 2-deoxygenation step in the biosynthesis of the deoxyhexose moieties of the antibiotics granaticin and oleandomycin.(J. Am. Chem. Soc.) [1999]
100
 C7QIW6_CATAD
(C7QIW6)		 
[query] 3 - 312 (312)
[subject] 13 - 321 (338)
 1e-94 350   58%
Product
dTDP-glucose 4,6-dehydratase
Gene
Caci_8193
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]