BLAST table : Aran_00150

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
A1C183_9ACTO
(A1C183)
[query] 1 - 269 (269)
[subject] 1 - 269 (269)
1e-146 521   100% Pathway specific transcription activator Streptomyces echinatus
2
E3T487_9ACTO
(E3T487)
[query] 5 - 256 (269)
[subject] 1 - 259 (278)
3e-81 306   64% Pathway-specific transcriptional activator gra-orf9 Streptomyces vietnamensis
3
Q9ZA48_STRVN
(Q9ZA48)
Jump to Grana_00030
[query] 3 - 259 (269)
[subject] 1 - 270 (283)
8e-80 301   61% Pathway-specific transcriptional activator gra-orf9 Streptomyces violaceoruber
4
D3U1V5_9BACT
(D3U1V5)
[query] 1 - 257 (269)
[subject] 1 - 260 (272)
3e-73 279   60% Putative pathway-specific transcriptional activator uncultured soil bacterium V167
5
B6SEG7_9ACTO
(B6SEG7)
Jump to Alnu_00220
[query] 3 - 254 (269)
[subject] 1 - 252 (271)
9e-70 268   57% AlnR3 SARP family regulator alnR3 Streptomyces sp. CM020
6
E4NBI0_KITSK
(E4NBI0)
[query] 3 - 259 (269)
[subject] 1 - 255 (269)
5e-65 252   54% Putative AfsR family transcriptional regulator KSE_27490 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
7
D1A6U2_THECD
(D1A6U2)
[query] 3 - 259 (269)
[subject] 2 - 255 (267)
1e-64 251   53% Transcriptional regulator, SARP family Tcur_2801 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
8
D6AAR9_9ACTO
(D6AAR9)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
9e-63 244   51% Putative uncharacterized protein SSFG_07839 Streptomyces ghanaensis ATCC 14672
9
E2Q9D3_STRCL
(E2Q9D3)
[query] 3 - 256 (269)
[subject] 1 - 253 (278)
6e-61 238   54% SARP family pathway specific regulatory protein SCLAV_0477 Streptomyces clavuligerus ATCC 27064
10
A2AXE3_STRCM
(A2AXE3)
[query] 3 - 259 (269)
[subject] 41 - 297 (313)
4e-60 235   51% Putative SARP family pathway-specific regulator fnq4 Streptomyces cinnamonensis
11
E1ARL7_STRAU
(E1ARL7)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
5e-60 235   52% Putative SARP family pathway specific regulatory protein sa35 Streptomyces aureofaciens
12
Q9L4V0_9ACTO
(Q9L4V0)
Jump to Acla_00170
[query] 3 - 259 (269)
[subject] 1 - 257 (272)
5e-60 235   51% Putative activator aknO Streptomyces galilaeus
13
DNRI_STRPE
(P25047)
Jump to Adria_00210
[query] 3 - 262 (269)
[subject] 1 - 260 (272)
8e-60 234   51% Regulatory protein dnrI dnrI Streptomyces peucetius
14
Q67G41_9ACTO
(Q67G41)
Jump to Heda_00170
[query] 3 - 261 (269)
[subject] 1 - 259 (272)
1e-59 234   49% Putative regulatory protein Streptomyces griseoruber
15
D9W573_9ACTO
(D9W573)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
1e-59 234   51% SARP family regulator SSNG_07303 Streptomyces sp. C
16
B5UAT1_STRLA
(B5UAT1)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-59 234   51% SARP family regulator farR3 Streptomyces lavendulae
17
Q8KSZ0_9ACTO
(Q8KSZ0)
Jump to Griseo_00020
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-59 233   50% Putative transcriptional activator GrhR2 grhR2 Streptomyces sp. JP95
18
Q83X33_STRRO
(Q83X33)
[query] 3 - 262 (269)
[subject] 1 - 260 (273)
3e-59 233   51% SARP family regulator SrrZ srrZ Streptomyces rochei
Streptomyces parvullus
19
C9ZCD2_STRSW
(C9ZCD2)
[query] 3 - 256 (269)
[subject] 1 - 253 (278)
3e-59 233   52% Putative regulatory protein SCAB_63171 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
20
Q2PA02_9ACTO
(Q2PA02)
Jump to Stref_00130
[query] 3 - 259 (269)
[subject] 1 - 257 (290)
3e-59 233   51% SARP family regulator stfRI Streptomyces steffisburgensis
21
Q2L6C8_9ACTO
(Q2L6C8)
[query] 2 - 259 (269)
[subject] 70 - 327 (343)
1e-58 230   49% Putative transcriptional regulator Streptomyces sp. KO-3988
22
Q6VMH5_STRAM
(Q6VMH5)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-58 230   51% Putative SARP family pathway specific regulatory protein alpT Streptomyces ambofaciens
23
Q1RQQ6_STRAM
(Q1RQQ6)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-58 230   51% Putative SARP family pathway specific regulatory protein alpT
SAMT0179
SAMT0180
Streptomyces ambofaciens ATCC 23877
24
B5HIW5_STRPR
(B5HIW5)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-58 230   50% Transcriptional activator domain-containing protein SSDG_05102 Streptomyces pristinaespiralis ATCC 25486
25
Q0JW87_STRAM
(Q0JW87)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
4e-58 229   51% Putative SARP family pathway specific regulatory protein DSMT0199 Streptomyces ambofaciens
26
D9WNL0_9ACTO
(D9WNL0)
[query] 3 - 259 (269)
[subject] 1 - 257 (274)
4e-58 229   53% Regulatory protein DnrI SSOG_05581 Streptomyces himastatinicus ATCC 53653
27
B5G8A6_9ACTO
(B5G8A6)
[query] 3 - 259 (269)
[subject] 48 - 304 (319)
5e-58 229   51% Transcriptional regulatory protein, C SSBG_00514 Streptomyces sp. SPB74
28
Q9KWX4_STRAM
(Q9KWX4)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
7e-58 228   51% Regulator (SAR) sar Streptomyces ambofaciens
29
E0KZW2_STRVO
(E0KZW2)
[query] 3 - 259 (269)
[subject] 1 - 257 (274)
3e-57 226   52% Transcriptional regulator, SARP family StrviDRAFT_8190 Streptomyces violaceusniger Tu 4113
30
D7BZQ7_STRBB
(D7BZQ7)
[query] 3 - 259 (269)
[subject] 1 - 257 (274)
2e-55 220   51% SARP family pathway specific regulatory protein SBI_06842 Streptomyces bingchenggensis (strain BCW-1)
31
Q83X49_STRRO
(Q83X49)
[query] 3 - 257 (269)
[subject] 1 - 258 (289)
5e-54 215   52% SARP family regulator SrrW srrW Streptomyces rochei
Streptomyces parvullus
32
A4X6X9_SALTO
(A4X6X9)
[query] 3 - 265 (269)
[subject] 8 - 269 (278)
7e-54 215   48% Transcriptional activator domain Strop_2178 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
33
D9UBT4_STRPR
(D9UBT4)
[query] 19 - 259 (269)
[subject] 2 - 242 (258)
9e-54 214   50% SARP-type regulator cpp1 Streptomyces pristinaespiralis
34
E1ARN1_STRAU
(E1ARN1)
[query] 3 - 259 (269)
[subject] 1 - 252 (268)
2e-53 213   48% Putative SARP family pathway specific regulatory protein sa23 Streptomyces aureofaciens
35
D6AXN0_9ACTO
(D6AXN0)
[query] 7 - 259 (269)
[subject] 18 - 271 (286)
6e-53 212   48% Putative uncharacterized protein SSHG_05322 Streptomyces albus J1074
36
D9UBV4_STRPR
(D9UBV4)
[query] 3 - 257 (269)
[subject] 1 - 256 (285)
8e-52 208   49% SARP-type regulator papR1 Streptomyces pristinaespiralis
37
D6X7H8_STRPR
(D6X7H8)
[query] 3 - 257 (269)
[subject] 1 - 256 (285)
8e-52 208   49% SARP family regulator SSDG_07486 Streptomyces pristinaespiralis ATCC 25486
38
E0KYL3_STRVO
(E0KYL3)
[query] 3 - 260 (269)
[subject] 1 - 259 (271)
2e-51 207   47% Transcriptional regulator, SARP family StrviDRAFT_7741 Streptomyces violaceusniger Tu 4113
39
D9WG83_9ACTO
(D9WG83)
[query] 3 - 265 (269)
[subject] 1 - 264 (271)
4e-51 206   45% Regulatory protein DnrI SSOG_03013 Streptomyces himastatinicus ATCC 53653
40
B5UAT2_STRLA
(B5UAT2)
[query] 3 - 257 (269)
[subject] 1 - 256 (273)
6e-51 205   49% SARP family regulator farR4 Streptomyces lavendulae
41
D6AAS1_9ACTO
(D6AAS1)
[query] 3 - 257 (269)
[subject] 1 - 261 (290)
7e-51 205   49% SARP family pathway specific regulatory protein SSFG_07841 Streptomyces ghanaensis ATCC 14672
42
D9W557_9ACTO
(D9W557)
[query] 14 - 259 (269)
[subject] 13 - 258 (274)
7e-51 205   49% SARP family regulator SSNG_07287 Streptomyces sp. C
43
D7CHH7_STRBB
(D7CHH7)
[query] 3 - 259 (269)
[subject] 1 - 258 (271)
8e-51 205   46% SARP family pathway specific regulatory protein SBI_03913 Streptomyces bingchenggensis (strain BCW-1)
44
E1ARL5_STRAU
(E1ARL5)
[query] 3 - 262 (269)
[subject] 1 - 265 (292)
1e-50 204   48% Putative SARP family pathway specific regulatory protein sa37 Streptomyces aureofaciens
45
Q83X29_STRRO
(Q83X29)
[query] 3 - 257 (269)
[subject] 1 - 259 (276)
2e-50 204   47% SARP family regulator SrrY srrY Streptomyces rochei
Streptomyces parvullus
46
Q9XCC4_STRFR
(Q9XCC4)
[query] 3 - 257 (269)
[subject] 1 - 259 (277)
2e-50 203   48% Hypothetical pathway specific regulatory protein TylS tylS Streptomyces fradiae
Streptomyces roseoflavus
47
E1ARN0_STRAU
(E1ARN0)
[query] 3 - 252 (269)
[subject] 1 - 251 (272)
5e-50 202   50% SARP family pathway specific regulatory protein sa24 Streptomyces aureofaciens
48
C6FX55_STRAS
(C6FX55)
[query] 3 - 264 (269)
[subject] 53 - 317 (323)
1e-49 201   46% NosP nosP Streptomyces actuosus
49
D9W572_9ACTO
(D9W572)
[query] 3 - 258 (269)
[subject] 1 - 257 (274)
1e-49 201   49% SARP family regulator SSNG_07302 Streptomyces sp. C
50
Q0JW85_STRAM
(Q0JW85)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47% Putative SARP family pathway specific regulatory protein DSMT0201 Streptomyces ambofaciens
51
D9UBW9_STRPR
(D9UBW9)
[query] 3 - 257 (269)
[subject] 1 - 283 (300)
2e-49 200   46% SARP-type regulator papR4 Streptomyces pristinaespiralis
52
Q6VMH3_STRAM
(Q6VMH3)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47% Putative SARP family pathway specific regulatory protein alpV Streptomyces ambofaciens
53
Q1RQQ4_STRAM
(Q1RQQ4)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47% Putative SARP family pathway specific regulatory protein alpV
SAMT0181
SAMT0182
Streptomyces ambofaciens ATCC 23877
54
E2EKL8_9ACTO
(E2EKL8)
[query] 3 - 259 (269)
[subject] 2 - 259 (610)
5e-49 199   46% Regulator sanR1 Streptomyces sp. SANK 61196
55
B0LIZ8_9ACTO
(B0LIZ8)
[query] 3 - 252 (269)
[subject] 1 - 253 (276)
4e-48 196   47% Lct15 lct15 Streptomyces rishiriensis
56
C0JWC2_9ACTO
(C0JWC2)
Jump to Polk_00270
[query] 3 - 263 (269)
[subject] 1 - 260 (270)
7e-48 195   45% PokR2 pokR2 Streptomyces diastatochromogenes
57
Q8KSZ1_9ACTO
(Q8KSZ1)
Jump to Griseo_00010
[query] 3 - 252 (269)
[subject] 1 - 254 (273)
4e-47 192   46% Putative transcriptional activator GrhR1 grhR1 Streptomyces sp. JP95
58
D2SZ12_MICEC
(D2SZ12)
[query] 3 - 266 (269)
[subject] 1 - 269 (293)
2e-46 190   44% Transcriptional regulator Micromonospora echinospora subsp. challisensis
59
Q194R8_STRAA
(Q194R8)
Jump to Mith_00020
[query] 5 - 254 (269)
[subject] 1 - 249 (276)
7e-46 188   42% Mithramycin regulator MtmR mtmR Streptomyces argillaceus
60
E8RWU1_MICSL
(E8RWU1)
[query] 3 - 256 (269)
[subject] 1 - 247 (651)
1e-44 184   47% Transcriptional regulator, SARP family ML5_4430 Micromonospora sp. (strain L5)
61
D9T288_MICAI
(D9T288)
[query] 3 - 256 (269)
[subject] 1 - 247 (651)
1e-44 184   47% Transcriptional activator domain Micau_3991 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
62
D2AY68_STRRD
(D2AY68)
[query] 3 - 255 (269)
[subject] 1 - 246 (621)
4e-44 182   43% Transcriptional regulator, SARP family Sros_4174 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
63
E0KYD3_STRVO
(E0KYD3)
[query] 3 - 260 (269)
[subject] 1 - 260 (276)
9e-44 181   45% Transcriptional regulator, SARP family StrviDRAFT_7661 Streptomyces violaceusniger Tu 4113
64
D9XKR3_9ACTO
(D9XKR3)
[query] 3 - 258 (269)
[subject] 1 - 256 (283)
1e-43 181   45% Regulatory protein DnrI SSRG_01305 Streptomyces griseoflavus Tu4000
65
Q9L545_9ACTO
(Q9L545)
Jump to Acla_00140
[query] 3 - 255 (269)
[subject] 1 - 253 (280)
1e-43 181   43% AknI aknI Streptomyces galilaeus
66
B0LJ06_9ACTO
(B0LJ06)
[query] 3 - 262 (269)
[subject] 1 - 258 (625)
1e-43 181   44% Lct23 lct23 Streptomyces rishiriensis
67
Q8VWA7_9ACTO
(Q8VWA7)
[query] 3 - 255 (269)
[subject] 1 - 253 (280)
1e-43 181   43% AclI aclI Streptomyces galilaeus
68
D6AEP3_STRFL
(D6AEP3)
[query] 3 - 265 (269)
[subject] 1 - 259 (262)
2e-43 180   41% Tylosin biosynthesis-specific regulatory protein tylS SSGG_02135 Streptomyces roseosporus NRRL 15998
69
D9W5M6_9ACTO
(D9W5M6)
[query] 3 - 255 (269)
[subject] 1 - 252 (1010)
3e-43 180   45% Predicted protein SSNG_07456 Streptomyces sp. C
70
C9ZCB7_STRSW
(C9ZCB7)
[query] 3 - 259 (269)
[subject] 1 - 249 (919)
4e-43 179   45% Putative transcriptional activator SCAB_63021 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
71
Q2MGB3_STRGR
(Q2MGB3)
Jump to Fred_00260
[query] 3 - 255 (269)
[subject] 2 - 256 (611)
3e-42 176   45% Regulatory protein Streptomyces griseus
72
Q9LBV5_STRVG
(Q9LBV5)
Jump to Virg_00290
[query] 3 - 257 (269)
[subject] 1 - 256 (271)
3e-42 176   45% Orf2 Streptomyces virginiae
73
D8I4K7_AMYMU
(D8I4K7)
[query] 3 - 256 (269)
[subject] 1 - 249 (617)
1e-41 174   43% SARP family transcriptional regulator AMED_5421 Amycolatopsis mediterranei (strain U-32)
74
B5G879_9ACTO
(B5G879)
[query] 3 - 257 (269)
[subject] 2 - 256 (281)
2e-41 173   42% Transcriptional regulatory protein, C SSBG_00487 Streptomyces sp. SPB74
75
Q70J84_STRGR
(Q70J84)
Jump to Chro_00140
[query] 23 - 259 (269)
[subject] 33 - 269 (300)
4e-41 172   44% Transcriptional regulator cmmRI Streptomyces griseus subsp. griseus
76
Q4R0M3_STRCX
(Q4R0M3)
Jump to Chart_00090
[query] 48 - 260 (269)
[subject] 1 - 213 (216)
4e-41 172   46% ChaR1 protein chaR1 Streptomyces chartreusis
77
E8W955_STRFA
(E8W955)
[query] 1 - 254 (269)
[subject] 2 - 250 (268)
2e-40 170   43% Transcriptional regulator, SARP family Sfla_5321 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
78
E5RLL0_9ACTO
(E5RLL0)
[query] 3 - 256 (269)
[subject] 1 - 250 (635)
5e-40 169   41% Putative transcriptional regulator pnxR2 Streptomyces sp. TA-0256
79
Q9KHL3_9ACTO
(Q9KHL3)
Jump to Enter_00020
[query] 3 - 267 (269)
[subject] 1 - 262 (283)
6e-40 169   40% Putative transcriptional regulator EncF encF Streptomyces maritimus
80
A7DWL6_STRTE
(A7DWL6)
[query] 3 - 262 (269)
[subject] 1 - 264 (613)
7e-40 168   42% Putative transcriptional activator, SARP family llpRIV Streptomyces tendae
81
E5DUG1_9NOCA
(E5DUG1)
[query] 3 - 255 (269)
[subject] 2 - 257 (299)
1e-39 167   41% NocP nocP Nocardia sp. ATCC 202099
82
E2Q9B8_STRCL
(E2Q9B8)
[query] 3 - 259 (269)
[subject] 1 - 260 (931)
2e-39 167   44% Putative regulatory protein AfsR-like protein SCLAV_0462 Streptomyces clavuligerus ATCC 27064
83
B1GSM4_9ACTO
(B1GSM4)
Jump to Bena_00140
[query] 3 - 257 (269)
[subject] 7 - 257 (656)
3e-39 166   41% BenR protein benR Streptomyces sp. A2991200
84
D2BBI6_STRRD
(D2BBI6)
[query] 3 - 256 (269)
[subject] 15 - 261 (378)
3e-39 166   43% Transcriptional regulator, SARP family Sros_1211 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
85
D9WRY0_9ACTO
(D9WRY0)
[query] 3 - 252 (269)
[subject] 1 - 250 (265)
8e-39 165   44% Regulatory protein DnrI SSOG_07938 Streptomyces himastatinicus ATCC 53653
86
Q7WT17_9ACTO
(Q7WT17)
Jump to Medem_00250
[query] 3 - 253 (269)
[subject] 1 - 249 (258)
1e-37 160   40% Pathway-specific transcriptional activator (SARP) med-ORF11 Streptomyces sp. AM-7161
87
C7PY63_CATAD
(C7PY63)
[query] 3 - 253 (269)
[subject] 1 - 251 (252)
2e-37 160   39% Transcriptional regulator, SARP family Caci_6503 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
88
D7CH46_STRBB
(D7CH46)
[query] 3 - 259 (269)
[subject] 1 - 252 (617)
2e-37 160   40% Transcriptional regulator, SARP family protein SBI_01760 Streptomyces bingchenggensis (strain BCW-1)
89
D7C811_STRBB
(D7C811)
[query] 3 - 265 (269)
[subject] 1 - 257 (939)
3e-37 159   41% Transcriptional regulator, SARP family protein SBI_01051 Streptomyces bingchenggensis (strain BCW-1)
90
D6MSY0_9ACTO
(D6MSY0)
[query] 3 - 256 (269)
[subject] 1 - 254 (270)
8e-37 158   42% SsfT1 ssfT1 Streptomyces sp. SF2575
91
Q8KY34_STRCU
(Q8KY34)
[query] 3 - 253 (269)
[subject] 16 - 274 (661)
8e-37 158   42% RubS rubS Streptomyces collinus
92
B5H7A5_STRPR
(B5H7A5)
[query] 3 - 259 (269)
[subject] 1 - 247 (993)
1e-36 157   42% Regulatory protein afsR SSDG_01051 Streptomyces pristinaespiralis ATCC 25486
93
Q2PC66_STRAH
(Q2PC66)
Jump to Rubra_00240
[query] 3 - 256 (269)
[subject] 1 - 251 (266)
2e-36 157   41% Putative regulator rubRg1 Streptomyces achromogenes subsp. rubradiris
94
Q2PC40_STRAH
(Q2PC40)
Jump to Rubra_00500
[query] 3 - 254 (269)
[subject] 1 - 249 (290)
5e-36 155   43% Putative transcription activator rubRg3 Streptomyces achromogenes subsp. rubradiris
95
Q1MWN3_STRLA
(Q1MWN3)
[query] 3 - 253 (269)
[subject] 1 - 249 (262)
5e-36 155   41% Putative pathway-specific transcriptional activator bpsB Streptomyces lavendulae subsp. lavendulae
96
D9VWN4_9ACTO
(D9VWN4)
[query] 4 - 254 (269)
[subject] 13 - 260 (264)
9e-36 155   38% Predicted protein SSNG_04494 Streptomyces sp. C
97
D6EWA9_STRLI
(D6EWA9)
[query] 3 - 255 (269)
[subject] 1 - 251 (255)
1e-35 154   41% Actinorhodin cluster activator protein SSPG_02604 Streptomyces lividans TK24
98
ACT24_STRCO
(P46106)
Jump to Actino_00160
[query] 3 - 255 (269)
[subject] 1 - 251 (255)
1e-35 154   41% Probable actinorhodin operon activatory protein actII-4
SCO5085
SCBAC28G1.11
Streptomyces coelicolor
99
C6WF44_ACTMD
(C6WF44)
[query] 2 - 266 (269)
[subject] 4 - 264 (1088)
1e-35 154   41% Transcriptional regulator, SARP family Amir_0205 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
100
Q54494_STRNO
(Q54494)
Jump to Nogl_00360
[query] 2 - 260 (269)
[subject] 27 - 278 (665)
3e-35 153   40% Snora snorA Streptomyces nogalater
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
3
Q9ZA48_STRVN
(Q9ZA48)
Jump to Grana_00030
[query] 3 - 259 (269)
[subject] 1 - 270 (283)
8e-80 301   61%
Product
Pathway-specific transcriptional activator
Gene
gra-orf9
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
5
B6SEG7_9ACTO
(B6SEG7)
Jump to Alnu_00220
[query] 3 - 254 (269)
[subject] 1 - 252 (271)
9e-70 268   57%
Product
AlnR3 SARP family regulator
Gene
alnR3
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
6
E4NBI0_KITSK
(E4NBI0)
[query] 3 - 259 (269)
[subject] 1 - 255 (269)
5e-65 252   54%
Product
Putative AfsR family transcriptional regulator
Gene
KSE_27490
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
7
D1A6U2_THECD
(D1A6U2)
[query] 3 - 259 (269)
[subject] 2 - 255 (267)
1e-64 251   53%
Product
Transcriptional regulator, SARP family
Gene
Tcur_2801
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
9
E2Q9D3_STRCL
(E2Q9D3)
[query] 3 - 256 (269)
[subject] 1 - 253 (278)
6e-61 238   54%
Product
SARP family pathway specific regulatory protein
Gene
SCLAV_0477
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
10
A2AXE3_STRCM
(A2AXE3)
[query] 3 - 259 (269)
[subject] 41 - 297 (313)
4e-60 235   51%
Product
Putative SARP family pathway-specific regulator
Gene
fnq4
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
11
E1ARL7_STRAU
(E1ARL7)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
5e-60 235   52%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa35
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
12
Q9L4V0_9ACTO
(Q9L4V0)
Jump to Acla_00170
[query] 3 - 259 (269)
[subject] 1 - 257 (272)
5e-60 235   51%
Product
Putative activator
Gene
aknO
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 11016846 [Medline] 20469061
A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000]
13
DNRI_STRPE
(P25047)
Jump to Adria_00210
[query] 3 - 262 (269)
[subject] 1 - 260 (272)
8e-60 234   51%
Product
Regulatory protein dnrI
Gene
dnrI
Organism
Streptomyces peucetius
1uniprot[Pubmed] 1729206 [Medline] 92104954
Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius.(J. Bacteriol.) [1992]
14
Q67G41_9ACTO
(Q67G41)
Jump to Heda_00170
[query] 3 - 261 (269)
[subject] 1 - 259 (272)
1e-59 234   49%
Product
Putative regulatory protein
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
16
B5UAT1_STRLA
(B5UAT1)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-59 234   51%
Product
SARP family regulator
Gene
farR3
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
17
Q8KSZ0_9ACTO
(Q8KSZ0)
Jump to Griseo_00020
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-59 233   50%
Product
Putative transcriptional activator GrhR2
Gene
grhR2
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
18
Q83X33_STRRO
(Q83X33)
[query] 3 - 262 (269)
[subject] 1 - 260 (273)
3e-59 233   51%
Product
SARP family regulator SrrZ
Gene
srrZ
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
19
C9ZCD2_STRSW
(C9ZCD2)
[query] 3 - 256 (269)
[subject] 1 - 253 (278)
3e-59 233   52%
Product
Putative regulatory protein
Gene
SCAB_63171
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
20
Q2PA02_9ACTO
(Q2PA02)
Jump to Stref_00130
[query] 3 - 259 (269)
[subject] 1 - 257 (290)
3e-59 233   51%
Product
SARP family regulator
Gene
stfRI
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
21
Q2L6C8_9ACTO
(Q2L6C8)
[query] 2 - 259 (269)
[subject] 70 - 327 (343)
1e-58 230   49%
Product
Putative transcriptional regulator
Gene
 
Organism
Streptomyces sp. KO-3988
1uniprot[Pubmed] 16452404
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.(J. Bacteriol.) [2006]
22
Q6VMH5_STRAM
(Q6VMH5)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-58 230   51%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
23
Q1RQQ6_STRAM
(Q1RQQ6)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
2e-58 230   51%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
SAMT0179
SAMT0180
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
25
Q0JW87_STRAM
(Q0JW87)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
4e-58 229   51%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0199
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
28
Q9KWX4_STRAM
(Q9KWX4)
[query] 3 - 259 (269)
[subject] 1 - 257 (273)
7e-58 228   51%
Product
Regulator (SAR)
Gene
sar
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 10628855 [Medline] 20092477
Cloning and characterization of a regulatory gene of the SARP family and its flanking region from Streptomyces ambofaciens.(Mol. Gen. Genet.) [1999]
30
D7BZQ7_STRBB
(D7BZQ7)
[query] 3 - 259 (269)
[subject] 1 - 257 (274)
2e-55 220   51%
Product
SARP family pathway specific regulatory protein
Gene
SBI_06842
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
31
Q83X49_STRRO
(Q83X49)
[query] 3 - 257 (269)
[subject] 1 - 258 (289)
5e-54 215   52%
Product
SARP family regulator SrrW
Gene
srrW
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
33
D9UBT4_STRPR
(D9UBT4)
[query] 19 - 259 (269)
[subject] 2 - 242 (258)
9e-54 214   50%
Product
SARP-type regulator
Gene
cpp1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
34
E1ARN1_STRAU
(E1ARN1)
[query] 3 - 259 (269)
[subject] 1 - 252 (268)
2e-53 213   48%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa23
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
36
D9UBV4_STRPR
(D9UBV4)
[query] 3 - 257 (269)
[subject] 1 - 256 (285)
8e-52 208   49%
Product
SARP-type regulator
Gene
papR1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
40
B5UAT2_STRLA
(B5UAT2)
[query] 3 - 257 (269)
[subject] 1 - 256 (273)
6e-51 205   49%
Product
SARP family regulator
Gene
farR4
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
43
D7CHH7_STRBB
(D7CHH7)
[query] 3 - 259 (269)
[subject] 1 - 258 (271)
8e-51 205   46%
Product
SARP family pathway specific regulatory protein
Gene
SBI_03913
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
44
E1ARL5_STRAU
(E1ARL5)
[query] 3 - 262 (269)
[subject] 1 - 265 (292)
1e-50 204   48%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa37
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
45
Q83X29_STRRO
(Q83X29)
[query] 3 - 257 (269)
[subject] 1 - 259 (276)
2e-50 204   47%
Product
SARP family regulator SrrY
Gene
srrY
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
46
Q9XCC4_STRFR
(Q9XCC4)
[query] 3 - 257 (269)
[subject] 1 - 259 (277)
2e-50 203   48%
Product
Hypothetical pathway specific regulatory protein TylS
Gene
tylS
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10467127 [Medline] 99398833
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae.(Chem. Biol.) [1999]
47
E1ARN0_STRAU
(E1ARN0)
[query] 3 - 252 (269)
[subject] 1 - 251 (272)
5e-50 202   50%
Product
SARP family pathway specific regulatory protein
Gene
sa24
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
50
Q0JW85_STRAM
(Q0JW85)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0201
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
51
D9UBW9_STRPR
(D9UBW9)
[query] 3 - 257 (269)
[subject] 1 - 283 (300)
2e-49 200   46%
Product
SARP-type regulator
Gene
papR4
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
52
Q6VMH3_STRAM
(Q6VMH3)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
53
Q1RQQ4_STRAM
(Q1RQQ4)
[query] 3 - 257 (269)
[subject] 1 - 259 (279)
2e-49 200   47%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
SAMT0181
SAMT0182
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
54
E2EKL8_9ACTO
(E2EKL8)
[query] 3 - 259 (269)
[subject] 2 - 259 (610)
5e-49 199   46%
Product
Regulator
Gene
sanR1
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
55
B0LIZ8_9ACTO
(B0LIZ8)
[query] 3 - 252 (269)
[subject] 1 - 253 (276)
4e-48 196   47%
Product
Lct15
Gene
lct15
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
56
C0JWC2_9ACTO
(C0JWC2)
Jump to Polk_00270
[query] 3 - 263 (269)
[subject] 1 - 260 (270)
7e-48 195   45%
Product
PokR2
Gene
pokR2
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
57
Q8KSZ1_9ACTO
(Q8KSZ1)
Jump to Griseo_00010
[query] 3 - 252 (269)
[subject] 1 - 254 (273)
4e-47 192   46%
Product
Putative transcriptional activator GrhR1
Gene
grhR1
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
58
D2SZ12_MICEC
(D2SZ12)
[query] 3 - 266 (269)
[subject] 1 - 269 (293)
2e-46 190   44%
Product
Transcriptional regulator
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
59
Q194R8_STRAA
(Q194R8)
Jump to Mith_00020
[query] 5 - 254 (269)
[subject] 1 - 249 (276)
7e-46 188   42%
Product
Mithramycin regulator MtmR
Gene
mtmR
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 9882681 [Medline] 99102230
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.(J. Bacteriol.) [1999]
6uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
7uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
8uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
9uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
10uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
11uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
12uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
13uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
14uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
15uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
16uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
17uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
18uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
19uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
20uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
21uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
62
D2AY68_STRRD
(D2AY68)
[query] 3 - 255 (269)
[subject] 1 - 246 (621)
4e-44 182   43%
Product
Transcriptional regulator, SARP family
Gene
Sros_4174
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
65
Q9L545_9ACTO
(Q9L545)
Jump to Acla_00140
[query] 3 - 255 (269)
[subject] 1 - 253 (280)
1e-43 181   43%
Product
AknI
Gene
aknI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
66
B0LJ06_9ACTO
(B0LJ06)
[query] 3 - 262 (269)
[subject] 1 - 258 (625)
1e-43 181   44%
Product
Lct23
Gene
lct23
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
67
Q8VWA7_9ACTO
(Q8VWA7)
[query] 3 - 255 (269)
[subject] 1 - 253 (280)
1e-43 181   43%
Product
AclI
Gene
aclI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
70
C9ZCB7_STRSW
(C9ZCB7)
[query] 3 - 259 (269)
[subject] 1 - 249 (919)
4e-43 179   45%
Product
Putative transcriptional activator
Gene
SCAB_63021
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
71
Q2MGB3_STRGR
(Q2MGB3)
Jump to Fred_00260
[query] 3 - 255 (269)
[subject] 2 - 256 (611)
3e-42 176   45%
Product
Regulatory protein
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 16305230
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005]
72
Q9LBV5_STRVG
(Q9LBV5)
Jump to Virg_00290
[query] 3 - 257 (269)
[subject] 1 - 256 (271)
3e-42 176   45%
Product
Orf2
Gene
 
Organism
Streptomyces virginiae
1uniprot[Pubmed] 10792718 [Medline] 20253310
Identification of an AfsA homologue (BarX) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis, virginiamycin biosynthesis and virginiamycin M1 resistance.(Mol. Microbiol.) [2000]
73
D8I4K7_AMYMU
(D8I4K7)
[query] 3 - 256 (269)
[subject] 1 - 249 (617)
1e-41 174   43%
Product
SARP family transcriptional regulator
Gene
AMED_5421
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
76
Q4R0M3_STRCX
(Q4R0M3)
Jump to Chart_00090
[query] 48 - 260 (269)
[subject] 1 - 213 (216)
4e-41 172   46%
Product
ChaR1 protein
Gene
chaR1
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
79
Q9KHL3_9ACTO
(Q9KHL3)
Jump to Enter_00020
[query] 3 - 267 (269)
[subject] 1 - 262 (283)
6e-40 169   40%
Product
Putative transcriptional regulator EncF
Gene
encF
Organism
Streptomyces maritimus
1uniprot
Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000]
2uniprot[Pubmed] 11137817 [Medline] 20579517
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000]
3uniprot[Pubmed] 11948863 [Medline] 21942282
A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001]
[pubmed all]
80
A7DWL6_STRTE
(A7DWL6)
[query] 3 - 262 (269)
[subject] 1 - 264 (613)
7e-40 168   42%
Product
Putative transcriptional activator, SARP family
Gene
llpRIV
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
81
E5DUG1_9NOCA
(E5DUG1)
[query] 3 - 255 (269)
[subject] 2 - 257 (299)
1e-39 167   41%
Product
NocP
Gene
nocP
Organism
Nocardia sp. ATCC 202099
1uniprot[Pubmed] 20473441
Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.(Mol. Biosyst.) [2010]
82
E2Q9B8_STRCL
(E2Q9B8)
[query] 3 - 259 (269)
[subject] 1 - 260 (931)
2e-39 167   44%
Product
Putative regulatory protein AfsR-like protein
Gene
SCLAV_0462
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
83
B1GSM4_9ACTO
(B1GSM4)
Jump to Bena_00140
[query] 3 - 257 (269)
[subject] 7 - 257 (656)
3e-39 166   41%
Product
BenR protein
Gene
benR
Organism
Streptomyces sp. A2991200
1uniprot[Pubmed] 17439117
Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007]
84
D2BBI6_STRRD
(D2BBI6)
[query] 3 - 256 (269)
[subject] 15 - 261 (378)
3e-39 166   43%
Product
Transcriptional regulator, SARP family
Gene
Sros_1211
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
86
Q7WT17_9ACTO
(Q7WT17)
Jump to Medem_00250
[query] 3 - 253 (269)
[subject] 1 - 249 (258)
1e-37 160   40%
Product
Pathway-specific transcriptional activator (SARP)
Gene
med-ORF11
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
87
C7PY63_CATAD
(C7PY63)
[query] 3 - 253 (269)
[subject] 1 - 251 (252)
2e-37 160   39%
Product
Transcriptional regulator, SARP family
Gene
Caci_6503
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
88
D7CH46_STRBB
(D7CH46)
[query] 3 - 259 (269)
[subject] 1 - 252 (617)
2e-37 160   40%
Product
Transcriptional regulator, SARP family protein
Gene
SBI_01760
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
89
D7C811_STRBB
(D7C811)
[query] 3 - 265 (269)
[subject] 1 - 257 (939)
3e-37 159   41%
Product
Transcriptional regulator, SARP family protein
Gene
SBI_01051
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
90
D6MSY0_9ACTO
(D6MSY0)
[query] 3 - 256 (269)
[subject] 1 - 254 (270)
8e-37 158   42%
Product
SsfT1
Gene
ssfT1
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
93
Q2PC66_STRAH
(Q2PC66)
Jump to Rubra_00240
[query] 3 - 256 (269)
[subject] 1 - 251 (266)
2e-36 157   41%
Product
Putative regulator
Gene
rubRg1
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
94
Q2PC40_STRAH
(Q2PC40)
Jump to Rubra_00500
[query] 3 - 254 (269)
[subject] 1 - 249 (290)
5e-36 155   43%
Product
Putative transcription activator
Gene
rubRg3
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
95
Q1MWN3_STRLA
(Q1MWN3)
[query] 3 - 253 (269)
[subject] 1 - 249 (262)
5e-36 155   41%
Product
Putative pathway-specific transcriptional activator
Gene
bpsB
Organism
Streptomyces lavendulae subsp. lavendulae
1uniprot[Pubmed] 17237222
Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis.(J. Biol. Chem.) [2007]
98
ACT24_STRCO
(P46106)
Jump to Actino_00160
[query] 3 - 255 (269)
[subject] 1 - 251 (255)
1e-35 154   41%
Product
Probable actinorhodin operon activatory protein
Gene
actII-4
SCO5085
SCBAC28G1.11
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1878971 [Medline] 91347376
The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces.(Cell) [1991]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
99
C6WF44_ACTMD
(C6WF44)
[query] 2 - 266 (269)
[subject] 4 - 264 (1088)
1e-35 154   41%
Product
Transcriptional regulator, SARP family
Gene
Amir_0205
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
100
Q54494_STRNO
(Q54494)
Jump to Nogl_00360
[query] 2 - 260 (269)
[subject] 27 - 278 (665)
3e-35 153   40%
Product
Snora
Gene
snorA
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]