BLAST table : Heda_00170

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q67G41_9ACTO
(Q67G41)		 
[query] 1 - 272 (272)
[subject] 1 - 272 (272)
 1e-152 541   100% Putative regulatory protein Streptomyces griseoruber
2
 D1A6U2_THECD
(D1A6U2)		 
[query] 1 - 258 (272)
[subject] 2 - 256 (267)
 2e-72 276   55% Transcriptional regulator, SARP family Tcur_2801 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
3
 E4NBI0_KITSK
(E4NBI0)		 
[query] 1 - 257 (272)
[subject] 1 - 255 (269)
 5e-70 268   56% Putative AfsR family transcriptional regulator KSE_27490 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
4
 Q2PA02_9ACTO
(Q2PA02)		 Jump to Stref_00130 
[query] 1 - 272 (272)
[subject] 1 - 264 (290)
 9e-70 268   54% SARP family regulator stfRI Streptomyces steffisburgensis
5
 DNRI_STRPE
(P25047)		 Jump to Adria_00210 
[query] 1 - 257 (272)
[subject] 1 - 257 (272)
 4e-68 262   53% Regulatory protein dnrI dnrI Streptomyces peucetius
6
 D9W573_9ACTO
(D9W573)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 2e-67 260   55% SARP family regulator SSNG_07303 Streptomyces sp. C
7
 B5UAT1_STRLA
(B5UAT1)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 8e-67 258   55% SARP family regulator farR3 Streptomyces lavendulae
8
 D6AAR9_9ACTO
(D6AAR9)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 5e-66 255   52% Putative uncharacterized protein SSFG_07839 Streptomyces ghanaensis ATCC 14672
9
 E1ARL7_STRAU
(E1ARL7)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 2e-65 253   53% Putative SARP family pathway specific regulatory protein sa35 Streptomyces aureofaciens
10
 Q8KSZ0_9ACTO
(Q8KSZ0)		 Jump to Griseo_00020 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 6e-65 251   53% Putative transcriptional activator GrhR2 grhR2 Streptomyces sp. JP95
11
 B5HIW5_STRPR
(B5HIW5)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 1e-64 251   54% Transcriptional activator domain-containing protein SSDG_05102 Streptomyces pristinaespiralis ATCC 25486
12
 Q9L4V0_9ACTO
(Q9L4V0)		 Jump to Acla_00170 
[query] 1 - 257 (272)
[subject] 1 - 257 (272)
 1e-64 250   54% Putative activator aknO Streptomyces galilaeus
13
 B5G8A6_9ACTO
(B5G8A6)		 
[query] 1 - 257 (272)
[subject] 48 - 304 (319)
 7e-64 248   56% Transcriptional regulatory protein, C SSBG_00514 Streptomyces sp. SPB74
14
 Q83X33_STRRO
(Q83X33)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 9e-64 248   52% SARP family regulator SrrZ srrZ Streptomyces rochei
Streptomyces parvullus
15
 B5UAT2_STRLA
(B5UAT2)		 
[query] 1 - 252 (272)
[subject] 1 - 253 (273)
 1e-63 247   54% SARP family regulator farR4 Streptomyces lavendulae
16
 Q2L6C8_9ACTO
(Q2L6C8)		 
[query] 1 - 262 (272)
[subject] 71 - 332 (343)
 5e-63 245   51% Putative transcriptional regulator Streptomyces sp. KO-3988
17
 C9ZCD2_STRSW
(C9ZCD2)		 
[query] 1 - 267 (272)
[subject] 1 - 261 (278)
 7e-63 244   51% Putative regulatory protein SCAB_63171 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
18
 Q6VMH5_STRAM
(Q6VMH5)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 3e-62 242   52% Putative SARP family pathway specific regulatory protein alpT Streptomyces ambofaciens
19
 Q1RQQ6_STRAM
(Q1RQQ6)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 3e-62 242   52% Putative SARP family pathway specific regulatory protein alpT
SAMT0179
SAMT0180		 Streptomyces ambofaciens ATCC 23877
20
 Q83X49_STRRO
(Q83X49)		 
[query] 1 - 268 (272)
[subject] 1 - 274 (289)
 5e-62 242   51% SARP family regulator SrrW srrW Streptomyces rochei
Streptomyces parvullus
21
 D9UBV4_STRPR
(D9UBV4)		 
[query] 1 - 250 (272)
[subject] 1 - 251 (285)
 6e-62 241   53% SARP-type regulator papR1 Streptomyces pristinaespiralis
22
 D6X7H8_STRPR
(D6X7H8)		 
[query] 1 - 250 (272)
[subject] 1 - 251 (285)
 6e-62 241   53% SARP family regulator SSDG_07486 Streptomyces pristinaespiralis ATCC 25486
23
 Q0JW87_STRAM
(Q0JW87)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 8e-62 241   52% Putative SARP family pathway specific regulatory protein DSMT0199 Streptomyces ambofaciens
24
 A2AXE3_STRCM
(A2AXE3)		 
[query] 1 - 262 (272)
[subject] 41 - 302 (313)
 8e-62 241   50% Putative SARP family pathway-specific regulator fnq4 Streptomyces cinnamonensis
25
 Q9KWX4_STRAM
(Q9KWX4)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 1e-61 240   52% Regulator (SAR) sar Streptomyces ambofaciens
26
 D9W572_9ACTO
(D9W572)		 
[query] 1 - 252 (272)
[subject] 1 - 253 (274)
 2e-61 240   53% SARP family regulator SSNG_07302 Streptomyces sp. C
27
 Q8KSZ1_9ACTO
(Q8KSZ1)		 Jump to Griseo_00010 
[query] 1 - 269 (272)
[subject] 1 - 272 (273)
 4e-61 239   50% Putative transcriptional activator GrhR1 grhR1 Streptomyces sp. JP95
28
 D9UBT4_STRPR
(D9UBT4)		 
[query] 16 - 262 (272)
[subject] 1 - 247 (258)
 4e-61 239   55% SARP-type regulator cpp1 Streptomyces pristinaespiralis
29
 B0LIZ8_9ACTO
(B0LIZ8)		 
[query] 1 - 255 (272)
[subject] 1 - 258 (276)
 7e-61 238   51% Lct15 lct15 Streptomyces rishiriensis
30
 E2Q9D3_STRCL
(E2Q9D3)		 
[query] 1 - 269 (272)
[subject] 1 - 270 (278)
 1e-60 237   50% SARP family pathway specific regulatory protein SCLAV_0477 Streptomyces clavuligerus ATCC 27064
31
 D9WNL0_9ACTO
(D9WNL0)		 
[query] 1 - 261 (272)
[subject] 1 - 261 (274)
 1e-60 237   52% Regulatory protein DnrI SSOG_05581 Streptomyces himastatinicus ATCC 53653
32
 D6AAS1_9ACTO
(D6AAS1)		 
[query] 1 - 272 (272)
[subject] 1 - 274 (290)
 1e-60 237   51% SARP family pathway specific regulatory protein SSFG_07841 Streptomyces ghanaensis ATCC 14672
33
 E1ARL5_STRAU
(E1ARL5)		 
[query] 1 - 250 (272)
[subject] 1 - 255 (292)
 1e-60 237   52% Putative SARP family pathway specific regulatory protein sa37 Streptomyces aureofaciens
34
 E1ARN1_STRAU
(E1ARN1)		 
[query] 1 - 262 (272)
[subject] 1 - 257 (268)
 3e-60 236   51% Putative SARP family pathway specific regulatory protein sa23 Streptomyces aureofaciens
35
 C6FX55_STRAS
(C6FX55)		 
[query] 1 - 259 (272)
[subject] 53 - 314 (323)
 4e-60 236   50% NosP nosP Streptomyces actuosus
36
 E0KZW2_STRVO
(E0KZW2)		 
[query] 1 - 261 (272)
[subject] 1 - 261 (274)
 1e-59 234   51% Transcriptional regulator, SARP family StrviDRAFT_8190 Streptomyces violaceusniger Tu 4113
37
 D7BZQ7_STRBB
(D7BZQ7)		 
[query] 1 - 258 (272)
[subject] 1 - 258 (274)
 1e-59 234   52% SARP family pathway specific regulatory protein SBI_06842 Streptomyces bingchenggensis (strain BCW-1)
38
 Q9XCC4_STRFR
(Q9XCC4)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (277)
 1e-59 234   50% Hypothetical pathway specific regulatory protein TylS tylS Streptomyces fradiae
Streptomyces roseoflavus
39
 A1C183_9ACTO
(A1C183)		 Jump to Aran_00150 
[query] 1 - 259 (272)
[subject] 3 - 261 (269)
 1e-59 234   49% Pathway specific transcription activator Streptomyces echinatus
40
 B6SEG7_9ACTO
(B6SEG7)		 Jump to Alnu_00220 
[query] 1 - 255 (272)
[subject] 1 - 255 (271)
 2e-59 234   51% AlnR3 SARP family regulator alnR3 Streptomyces sp. CM020
41
 D9W557_9ACTO
(D9W557)		 
[query] 17 - 262 (272)
[subject] 18 - 263 (274)
 2e-59 233   54% SARP family regulator SSNG_07287 Streptomyces sp. C
42
 E3T487_9ACTO
(E3T487)		 
[query] 5 - 258 (272)
[subject] 3 - 263 (278)
 2e-58 230   51% Pathway-specific transcriptional activator gra-orf9 Streptomyces vietnamensis
43
 Q6VMH3_STRAM
(Q6VMH3)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 3e-58 229   50% Putative SARP family pathway specific regulatory protein alpV Streptomyces ambofaciens
44
 Q1RQQ4_STRAM
(Q1RQQ4)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 3e-58 229   50% Putative SARP family pathway specific regulatory protein alpV
SAMT0181
SAMT0182		 Streptomyces ambofaciens ATCC 23877
45
 Q0JW85_STRAM
(Q0JW85)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 4e-58 229   50% Putative SARP family pathway specific regulatory protein DSMT0201 Streptomyces ambofaciens
46
 D3U1V5_9BACT
(D3U1V5)		 
[query] 1 - 258 (272)
[subject] 3 - 263 (272)
 6e-58 228   50% Putative pathway-specific transcriptional activator uncultured soil bacterium V167
47
 D6AXN0_9ACTO
(D6AXN0)		 
[query] 3 - 258 (272)
[subject] 16 - 272 (286)
 9e-58 228   49% Putative uncharacterized protein SSHG_05322 Streptomyces albus J1074
48
 Q83X29_STRRO
(Q83X29)		 
[query] 1 - 263 (272)
[subject] 1 - 266 (276)
 9e-58 228   49% SARP family regulator SrrY srrY Streptomyces rochei
Streptomyces parvullus
49
 D9UBW9_STRPR
(D9UBW9)		 
[query] 1 - 264 (272)
[subject] 1 - 290 (300)
 4e-57 226   47% SARP-type regulator papR4 Streptomyces pristinaespiralis
50
 E1ARN0_STRAU
(E1ARN0)		 
[query] 1 - 252 (272)
[subject] 1 - 253 (272)
 4e-57 226   51% SARP family pathway specific regulatory protein sa24 Streptomyces aureofaciens
51
 Q9ZA48_STRVN
(Q9ZA48)		 Jump to Grana_00030 
[query] 1 - 257 (272)
[subject] 1 - 270 (283)
 1e-56 224   48% Pathway-specific transcriptional activator gra-orf9 Streptomyces violaceoruber
52
 A4X6X9_SALTO
(A4X6X9)		 
[query] 1 - 257 (272)
[subject] 8 - 262 (278)
 2e-56 223   50% Transcriptional activator domain Strop_2178 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
53
 Q9LBV5_STRVG
(Q9LBV5)		 Jump to Virg_00290 
[query] 1 - 263 (272)
[subject] 1 - 263 (271)
 6e-55 218   49% Orf2 Streptomyces virginiae
54
 D2AY68_STRRD
(D2AY68)		 
[query] 1 - 270 (272)
[subject] 1 - 263 (621)
 3e-53 213   46% Transcriptional regulator, SARP family Sros_4174 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
55
 D2SZ12_MICEC
(D2SZ12)		 
[query] 1 - 266 (272)
[subject] 1 - 268 (293)
 9e-53 211   46% Transcriptional regulator Micromonospora echinospora subsp. challisensis
56
 E0KYL3_STRVO
(E0KYL3)		 
[query] 1 - 257 (272)
[subject] 1 - 258 (271)
 2e-52 210   48% Transcriptional regulator, SARP family StrviDRAFT_7741 Streptomyces violaceusniger Tu 4113
57
 A7DWL6_STRTE
(A7DWL6)		 
[query] 1 - 257 (272)
[subject] 1 - 261 (613)
 3e-52 209   47% Putative transcriptional activator, SARP family llpRIV Streptomyces tendae
58
 D7CHH7_STRBB
(D7CHH7)		 
[query] 1 - 257 (272)
[subject] 1 - 258 (271)
 4e-52 209   47% SARP family pathway specific regulatory protein SBI_03913 Streptomyces bingchenggensis (strain BCW-1)
59
 Q9KHL3_9ACTO
(Q9KHL3)		 Jump to Enter_00020 
[query] 1 - 258 (272)
[subject] 1 - 255 (283)
 1e-50 204   45% Putative transcriptional regulator EncF encF Streptomyces maritimus
60
 E5DUG1_9NOCA
(E5DUG1)		 
[query] 1 - 253 (272)
[subject] 2 - 257 (299)
 2e-50 204   43% NocP nocP Nocardia sp. ATCC 202099
61
 E8W955_STRFA
(E8W955)		 
[query] 5 - 252 (272)
[subject] 8 - 250 (268)
 2e-50 203   47% Transcriptional regulator, SARP family Sfla_5321 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
62
 D9XKR3_9ACTO
(D9XKR3)		 
[query] 1 - 254 (272)
[subject] 1 - 254 (283)
 1e-49 201   49% Regulatory protein DnrI SSRG_01305 Streptomyces griseoflavus Tu4000
63
 D9WG83_9ACTO
(D9WG83)		 
[query] 1 - 257 (272)
[subject] 1 - 258 (271)
 1e-49 201   47% Regulatory protein DnrI SSOG_03013 Streptomyces himastatinicus ATCC 53653
64
 D8I4K7_AMYMU
(D8I4K7)		 
[query] 1 - 256 (272)
[subject] 1 - 251 (617)
 3e-49 199   46% SARP family transcriptional regulator AMED_5421 Amycolatopsis mediterranei (strain U-32)
65
 D9W5M6_9ACTO
(D9W5M6)		 
[query] 1 - 256 (272)
[subject] 1 - 255 (1010)
 2e-47 194   46% Predicted protein SSNG_07456 Streptomyces sp. C
66
 E2EKL8_9ACTO
(E2EKL8)		 
[query] 1 - 258 (272)
[subject] 2 - 260 (610)
 3e-47 193   45% Regulator sanR1 Streptomyces sp. SANK 61196
67
 C0JWC2_9ACTO
(C0JWC2)		 Jump to Polk_00270 
[query] 1 - 250 (272)
[subject] 1 - 249 (270)
 3e-47 193   46% PokR2 pokR2 Streptomyces diastatochromogenes
68
 Q194R8_STRAA
(Q194R8)		 Jump to Mith_00020 
[query] 3 - 252 (272)
[subject] 1 - 249 (276)
 3e-47 193   45% Mithramycin regulator MtmR mtmR Streptomyces argillaceus
69
 E5RLL0_9ACTO
(E5RLL0)		 
[query] 1 - 258 (272)
[subject] 1 - 254 (635)
 7e-47 192   43% Putative transcriptional regulator pnxR2 Streptomyces sp. TA-0256
70
 Q70J84_STRGR
(Q70J84)		 Jump to Chro_00140 
[query] 21 - 257 (272)
[subject] 33 - 269 (300)
 2e-46 190   45% Transcriptional regulator cmmRI Streptomyces griseus subsp. griseus
71
 Q8VWA7_9ACTO
(Q8VWA7)		 
[query] 1 - 257 (272)
[subject] 1 - 257 (280)
 5e-46 189   43% AclI aclI Streptomyces galilaeus
72
 E0KYD3_STRVO
(E0KYD3)		 
[query] 1 - 258 (272)
[subject] 1 - 258 (276)
 6e-46 189   43% Transcriptional regulator, SARP family StrviDRAFT_7661 Streptomyces violaceusniger Tu 4113
73
 Q9L545_9ACTO
(Q9L545)		 Jump to Acla_00140 
[query] 1 - 262 (272)
[subject] 1 - 258 (280)
 8e-46 188   43% AknI aknI Streptomyces galilaeus
74
 Q4R0M3_STRCX
(Q4R0M3)		 Jump to Chart_00090 
[query] 48 - 257 (272)
[subject] 3 - 212 (216)
 1e-45 187   50% ChaR1 protein chaR1 Streptomyces chartreusis
75
 C9ZCB7_STRSW
(C9ZCB7)		 
[query] 1 - 257 (272)
[subject] 1 - 249 (919)
 4e-45 186   45% Putative transcriptional activator SCAB_63021 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
76
 D6AEP3_STRFL
(D6AEP3)		 
[query] 1 - 258 (272)
[subject] 1 - 254 (262)
 4e-45 186   40% Tylosin biosynthesis-specific regulatory protein tylS SSGG_02135 Streptomyces roseosporus NRRL 15998
77
 B5G879_9ACTO
(B5G879)		 
[query] 1 - 255 (272)
[subject] 2 - 256 (281)
 8e-45 185   42% Transcriptional regulatory protein, C SSBG_00487 Streptomyces sp. SPB74
78
 C7PY63_CATAD
(C7PY63)		 
[query] 1 - 252 (272)
[subject] 1 - 252 (252)
 2e-44 184   40% Transcriptional regulator, SARP family Caci_6503 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
79
 F2R3G1_STRVP
(F2R3G1)		 
[query] 1 - 250 (272)
[subject] 1 - 260 (293)
 1e-43 181   45% Putative SARP family pathway specific regulatory protein SVEN_2517 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
80
 D7CH46_STRBB
(D7CH46)		 
[query] 1 - 257 (272)
[subject] 1 - 252 (617)
 5e-43 179   42% Transcriptional regulator, SARP family protein SBI_01760 Streptomyces bingchenggensis (strain BCW-1)
81
 B1GSM4_9ACTO
(B1GSM4)		 Jump to Bena_00140 
[query] 1 - 256 (272)
[subject] 7 - 258 (656)
 8e-43 178   41% BenR protein benR Streptomyces sp. A2991200
82
 Q2MGB3_STRGR
(Q2MGB3)		 Jump to Fred_00260 
[query] 1 - 258 (272)
[subject] 2 - 261 (611)
 1e-42 177   44% Regulatory protein Streptomyces griseus
83
 Q54494_STRNO
(Q54494)		 Jump to Nogl_00360 
[query] 1 - 250 (272)
[subject] 28 - 269 (665)
 2e-42 177   42% Snora snorA Streptomyces nogalater
84
 E3J3Q3_FRASU
(E3J3Q3)		 
[query] 2 - 252 (272)
[subject] 74 - 321 (322)
 3e-42 176   42% Transcriptional regulator, SARP family FraEuI1c_1323 Frankia sp. (strain EuI1c)
85
 E8RWU1_MICSL
(E8RWU1)		 
[query] 1 - 268 (272)
[subject] 1 - 258 (651)
 6e-42 175   42% Transcriptional regulator, SARP family ML5_4430 Micromonospora sp. (strain L5)
86
 D9T288_MICAI
(D9T288)		 
[query] 1 - 268 (272)
[subject] 1 - 258 (651)
 6e-42 175   42% Transcriptional activator domain Micau_3991 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
87
 Q8KY34_STRCU
(Q8KY34)		 
[query] 1 - 272 (272)
[subject] 16 - 292 (661)
 1e-41 174   42% RubS rubS Streptomyces collinus
88
 D6AEN6_STRFL
(D6AEN6)		 
[query] 1 - 262 (272)
[subject] 13 - 275 (304)
 5e-41 172   39% Regulatory protein dnrI SSGG_02128 Streptomyces roseosporus NRRL 15998
89
 D2S8X8_GEOOG
(D2S8X8)		 
[query] 1 - 265 (272)
[subject] 1 - 260 (1000)
 1e-40 171   40% Transcriptional regulator, SARP family Gobs_0857 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
90
 E2Q9B8_STRCL
(E2Q9B8)		 
[query] 1 - 257 (272)
[subject] 1 - 260 (931)
 1e-40 171   41% Putative regulatory protein AfsR-like protein SCLAV_0462 Streptomyces clavuligerus ATCC 27064
91
 E2D2K1_9BACT
(E2D2K1)		 
[query] 1 - 250 (272)
[subject] 6 - 255 (258)
 3e-40 169   40% Pathway specific transcriptional regulator uncultured soil bacterium
92
 C7N0E0_SACVD
(C7N0E0)		 
[query] 1 - 253 (272)
[subject] 1 - 250 (631)
 3e-40 169   41% DNA-binding transcriptional activator of the SARP family Svir_33780 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
93
 B0LJ06_9ACTO
(B0LJ06)		 
[query] 1 - 263 (272)
[subject] 1 - 261 (625)
 3e-40 169   43% Lct23 lct23 Streptomyces rishiriensis
94
 O68913_9ACTO
(O68913)		 Jump to Fren_00070 
[query] 1 - 250 (272)
[subject] 1 - 251 (282)
 1e-39 167   44% Pathway specific regulator frnG Streptomyces roseofulvus
95
 D9UKN0_9ACTO
(D9UKN0)		 
[query] 1 - 250 (272)
[subject] 1 - 251 (282)
 1e-39 167   43% Pathway specific regulator SSLG_05746 Streptomyces sp. SPB78
96
 D2BBI6_STRRD
(D2BBI6)		 
[query] 1 - 256 (272)
[subject] 15 - 263 (378)
 2e-39 167   39% Transcriptional regulator, SARP family Sros_1211 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
97
 D9WMS0_9ACTO
(D9WMS0)		 
[query] 1 - 252 (272)
[subject] 29 - 273 (279)
 3e-39 166   40% Regulatory protein DnrI SSOG_07650 Streptomyces himastatinicus ATCC 53653
98
 D9W8G2_9ACTO
(D9W8G2)		 
[query] 1 - 258 (272)
[subject] 1 - 258 (260)
 8e-39 165   40% Regulatory protein DnrI SSOG_02383 Streptomyces himastatinicus ATCC 53653
99
 Q7WT17_9ACTO
(Q7WT17)		 Jump to Medem_00250 
[query] 1 - 250 (272)
[subject] 1 - 248 (258)
 2e-38 164   41% Pathway-specific transcriptional activator (SARP) med-ORF11 Streptomyces sp. AM-7161
100
 Q0RI37_FRAAA
(Q0RI37)		 
[query] 1 - 256 (272)
[subject] 4 - 256 (456)
 2e-38 163   39% Putative transcriptional regulator FRAAL4193 Frankia alni (strain ACN14a)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q67G41_9ACTO
(Q67G41)		 
[query] 1 - 272 (272)
[subject] 1 - 272 (272)
 1e-152 541   100%
Product
Putative regulatory protein
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
2
 D1A6U2_THECD
(D1A6U2)		 
[query] 1 - 258 (272)
[subject] 2 - 256 (267)
 2e-72 276   55%
Product
Transcriptional regulator, SARP family
Gene
Tcur_2801
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
3
 E4NBI0_KITSK
(E4NBI0)		 
[query] 1 - 257 (272)
[subject] 1 - 255 (269)
 5e-70 268   56%
Product
Putative AfsR family transcriptional regulator
Gene
KSE_27490
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
4
 Q2PA02_9ACTO
(Q2PA02)		 Jump to Stref_00130 
[query] 1 - 272 (272)
[subject] 1 - 264 (290)
 9e-70 268   54%
Product
SARP family regulator
Gene
stfRI
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
5
 DNRI_STRPE
(P25047)		 Jump to Adria_00210 
[query] 1 - 257 (272)
[subject] 1 - 257 (272)
 4e-68 262   53%
Product
Regulatory protein dnrI
Gene
dnrI
Organism
Streptomyces peucetius
1uniprot[Pubmed] 1729206 [Medline] 92104954
Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius.(J. Bacteriol.) [1992]
7
 B5UAT1_STRLA
(B5UAT1)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 8e-67 258   55%
Product
SARP family regulator
Gene
farR3
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
9
 E1ARL7_STRAU
(E1ARL7)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 2e-65 253   53%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa35
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
10
 Q8KSZ0_9ACTO
(Q8KSZ0)		 Jump to Griseo_00020 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 6e-65 251   53%
Product
Putative transcriptional activator GrhR2
Gene
grhR2
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
12
 Q9L4V0_9ACTO
(Q9L4V0)		 Jump to Acla_00170 
[query] 1 - 257 (272)
[subject] 1 - 257 (272)
 1e-64 250   54%
Product
Putative activator
Gene
aknO
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 11016846 [Medline] 20469061
A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000]
14
 Q83X33_STRRO
(Q83X33)		 
[query] 1 - 262 (272)
[subject] 1 - 262 (273)
 9e-64 248   52%
Product
SARP family regulator SrrZ
Gene
srrZ
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
15
 B5UAT2_STRLA
(B5UAT2)		 
[query] 1 - 252 (272)
[subject] 1 - 253 (273)
 1e-63 247   54%
Product
SARP family regulator
Gene
farR4
Organism
Streptomyces lavendulae
1uniprot
Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008]
16
 Q2L6C8_9ACTO
(Q2L6C8)		 
[query] 1 - 262 (272)
[subject] 71 - 332 (343)
 5e-63 245   51%
Product
Putative transcriptional regulator
Gene
 
Organism
Streptomyces sp. KO-3988
1uniprot[Pubmed] 16452404
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.(J. Bacteriol.) [2006]
17
 C9ZCD2_STRSW
(C9ZCD2)		 
[query] 1 - 267 (272)
[subject] 1 - 261 (278)
 7e-63 244   51%
Product
Putative regulatory protein
Gene
SCAB_63171
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
18
 Q6VMH5_STRAM
(Q6VMH5)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 3e-62 242   52%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
19
 Q1RQQ6_STRAM
(Q1RQQ6)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 3e-62 242   52%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpT
SAMT0179
SAMT0180
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
20
 Q83X49_STRRO
(Q83X49)		 
[query] 1 - 268 (272)
[subject] 1 - 274 (289)
 5e-62 242   51%
Product
SARP family regulator SrrW
Gene
srrW
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
21
 D9UBV4_STRPR
(D9UBV4)		 
[query] 1 - 250 (272)
[subject] 1 - 251 (285)
 6e-62 241   53%
Product
SARP-type regulator
Gene
papR1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
23
 Q0JW87_STRAM
(Q0JW87)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 8e-62 241   52%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0199
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
24
 A2AXE3_STRCM
(A2AXE3)		 
[query] 1 - 262 (272)
[subject] 41 - 302 (313)
 8e-62 241   50%
Product
Putative SARP family pathway-specific regulator
Gene
fnq4
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
25
 Q9KWX4_STRAM
(Q9KWX4)		 
[query] 1 - 259 (272)
[subject] 1 - 259 (273)
 1e-61 240   52%
Product
Regulator (SAR)
Gene
sar
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 10628855 [Medline] 20092477
Cloning and characterization of a regulatory gene of the SARP family and its flanking region from Streptomyces ambofaciens.(Mol. Gen. Genet.) [1999]
27
 Q8KSZ1_9ACTO
(Q8KSZ1)		 Jump to Griseo_00010 
[query] 1 - 269 (272)
[subject] 1 - 272 (273)
 4e-61 239   50%
Product
Putative transcriptional activator GrhR1
Gene
grhR1
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
28
 D9UBT4_STRPR
(D9UBT4)		 
[query] 16 - 262 (272)
[subject] 1 - 247 (258)
 4e-61 239   55%
Product
SARP-type regulator
Gene
cpp1
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
29
 B0LIZ8_9ACTO
(B0LIZ8)		 
[query] 1 - 255 (272)
[subject] 1 - 258 (276)
 7e-61 238   51%
Product
Lct15
Gene
lct15
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
30
 E2Q9D3_STRCL
(E2Q9D3)		 
[query] 1 - 269 (272)
[subject] 1 - 270 (278)
 1e-60 237   50%
Product
SARP family pathway specific regulatory protein
Gene
SCLAV_0477
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
33
 E1ARL5_STRAU
(E1ARL5)		 
[query] 1 - 250 (272)
[subject] 1 - 255 (292)
 1e-60 237   52%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa37
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
34
 E1ARN1_STRAU
(E1ARN1)		 
[query] 1 - 262 (272)
[subject] 1 - 257 (268)
 3e-60 236   51%
Product
Putative SARP family pathway specific regulatory protein
Gene
sa23
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
37
 D7BZQ7_STRBB
(D7BZQ7)		 
[query] 1 - 258 (272)
[subject] 1 - 258 (274)
 1e-59 234   52%
Product
SARP family pathway specific regulatory protein
Gene
SBI_06842
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
38
 Q9XCC4_STRFR
(Q9XCC4)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (277)
 1e-59 234   50%
Product
Hypothetical pathway specific regulatory protein TylS
Gene
tylS
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10467127 [Medline] 99398833
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae.(Chem. Biol.) [1999]
40
 B6SEG7_9ACTO
(B6SEG7)		 Jump to Alnu_00220 
[query] 1 - 255 (272)
[subject] 1 - 255 (271)
 2e-59 234   51%
Product
AlnR3 SARP family regulator
Gene
alnR3
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
43
 Q6VMH3_STRAM
(Q6VMH3)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 3e-58 229   50%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
44
 Q1RQQ4_STRAM
(Q1RQQ4)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 3e-58 229   50%
Product
Putative SARP family pathway specific regulatory protein
Gene
alpV
SAMT0181
SAMT0182
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
45
 Q0JW85_STRAM
(Q0JW85)		 
[query] 1 - 250 (272)
[subject] 1 - 254 (279)
 4e-58 229   50%
Product
Putative SARP family pathway specific regulatory protein
Gene
DSMT0201
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
48
 Q83X29_STRRO
(Q83X29)		 
[query] 1 - 263 (272)
[subject] 1 - 266 (276)
 9e-58 228   49%
Product
SARP family regulator SrrY
Gene
srrY
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
49
 D9UBW9_STRPR
(D9UBW9)		 
[query] 1 - 264 (272)
[subject] 1 - 290 (300)
 4e-57 226   47%
Product
SARP-type regulator
Gene
papR4
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
50
 E1ARN0_STRAU
(E1ARN0)		 
[query] 1 - 252 (272)
[subject] 1 - 253 (272)
 4e-57 226   51%
Product
SARP family pathway specific regulatory protein
Gene
sa24
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
51
 Q9ZA48_STRVN
(Q9ZA48)		 Jump to Grana_00030 
[query] 1 - 257 (272)
[subject] 1 - 270 (283)
 1e-56 224   48%
Product
Pathway-specific transcriptional activator
Gene
gra-orf9
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
53
 Q9LBV5_STRVG
(Q9LBV5)		 Jump to Virg_00290 
[query] 1 - 263 (272)
[subject] 1 - 263 (271)
 6e-55 218   49%
Product
Orf2
Gene
 
Organism
Streptomyces virginiae
1uniprot[Pubmed] 10792718 [Medline] 20253310
Identification of an AfsA homologue (BarX) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis, virginiamycin biosynthesis and virginiamycin M1 resistance.(Mol. Microbiol.) [2000]
54
 D2AY68_STRRD
(D2AY68)		 
[query] 1 - 270 (272)
[subject] 1 - 263 (621)
 3e-53 213   46%
Product
Transcriptional regulator, SARP family
Gene
Sros_4174
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
55
 D2SZ12_MICEC
(D2SZ12)		 
[query] 1 - 266 (272)
[subject] 1 - 268 (293)
 9e-53 211   46%
Product
Transcriptional regulator
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
57
 A7DWL6_STRTE
(A7DWL6)		 
[query] 1 - 257 (272)
[subject] 1 - 261 (613)
 3e-52 209   47%
Product
Putative transcriptional activator, SARP family
Gene
llpRIV
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
58
 D7CHH7_STRBB
(D7CHH7)		 
[query] 1 - 257 (272)
[subject] 1 - 258 (271)
 4e-52 209   47%
Product
SARP family pathway specific regulatory protein
Gene
SBI_03913
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
59
 Q9KHL3_9ACTO
(Q9KHL3)		 Jump to Enter_00020 
[query] 1 - 258 (272)
[subject] 1 - 255 (283)
 1e-50 204   45%
Product
Putative transcriptional regulator EncF
Gene
encF
Organism
Streptomyces maritimus
1uniprot
Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000]
2uniprot[Pubmed] 11137817 [Medline] 20579517
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000]
3uniprot[Pubmed] 11948863 [Medline] 21942282
A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001]
[pubmed all]
60
 E5DUG1_9NOCA
(E5DUG1)		 
[query] 1 - 253 (272)
[subject] 2 - 257 (299)
 2e-50 204   43%
Product
NocP
Gene
nocP
Organism
Nocardia sp. ATCC 202099
1uniprot[Pubmed] 20473441
Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.(Mol. Biosyst.) [2010]
64
 D8I4K7_AMYMU
(D8I4K7)		 
[query] 1 - 256 (272)
[subject] 1 - 251 (617)
 3e-49 199   46%
Product
SARP family transcriptional regulator
Gene
AMED_5421
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
66
 E2EKL8_9ACTO
(E2EKL8)		 
[query] 1 - 258 (272)
[subject] 2 - 260 (610)
 3e-47 193   45%
Product
Regulator
Gene
sanR1
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
67
 C0JWC2_9ACTO
(C0JWC2)		 Jump to Polk_00270 
[query] 1 - 250 (272)
[subject] 1 - 249 (270)
 3e-47 193   46%
Product
PokR2
Gene
pokR2
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
68
 Q194R8_STRAA
(Q194R8)		 Jump to Mith_00020 
[query] 3 - 252 (272)
[subject] 1 - 249 (276)
 3e-47 193   45%
Product
Mithramycin regulator MtmR
Gene
mtmR
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 9882681 [Medline] 99102230
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.(J. Bacteriol.) [1999]
6uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
7uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
8uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
9uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
10uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
11uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
12uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
13uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
14uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
15uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
16uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
17uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
18uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
19uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
20uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
21uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
71
 Q8VWA7_9ACTO
(Q8VWA7)		 
[query] 1 - 257 (272)
[subject] 1 - 257 (280)
 5e-46 189   43%
Product
AclI
Gene
aclI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
73
 Q9L545_9ACTO
(Q9L545)		 Jump to Acla_00140 
[query] 1 - 262 (272)
[subject] 1 - 258 (280)
 8e-46 188   43%
Product
AknI
Gene
aknI
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
74
 Q4R0M3_STRCX
(Q4R0M3)		 Jump to Chart_00090 
[query] 48 - 257 (272)
[subject] 3 - 212 (216)
 1e-45 187   50%
Product
ChaR1 protein
Gene
chaR1
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
75
 C9ZCB7_STRSW
(C9ZCB7)		 
[query] 1 - 257 (272)
[subject] 1 - 249 (919)
 4e-45 186   45%
Product
Putative transcriptional activator
Gene
SCAB_63021
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
78
 C7PY63_CATAD
(C7PY63)		 
[query] 1 - 252 (272)
[subject] 1 - 252 (252)
 2e-44 184   40%
Product
Transcriptional regulator, SARP family
Gene
Caci_6503
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
79
 F2R3G1_STRVP
(F2R3G1)		 
[query] 1 - 250 (272)
[subject] 1 - 260 (293)
 1e-43 181   45%
Product
Putative SARP family pathway specific regulatory protein
Gene
SVEN_2517
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
80
 D7CH46_STRBB
(D7CH46)		 
[query] 1 - 257 (272)
[subject] 1 - 252 (617)
 5e-43 179   42%
Product
Transcriptional regulator, SARP family protein
Gene
SBI_01760
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
81
 B1GSM4_9ACTO
(B1GSM4)		 Jump to Bena_00140 
[query] 1 - 256 (272)
[subject] 7 - 258 (656)
 8e-43 178   41%
Product
BenR protein
Gene
benR
Organism
Streptomyces sp. A2991200
1uniprot[Pubmed] 17439117
Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007]
82
 Q2MGB3_STRGR
(Q2MGB3)		 Jump to Fred_00260 
[query] 1 - 258 (272)
[subject] 2 - 261 (611)
 1e-42 177   44%
Product
Regulatory protein
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 16305230
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005]
83
 Q54494_STRNO
(Q54494)		 Jump to Nogl_00360 
[query] 1 - 250 (272)
[subject] 28 - 269 (665)
 2e-42 177   42%
Product
Snora
Gene
snorA
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
90
 E2Q9B8_STRCL
(E2Q9B8)		 
[query] 1 - 257 (272)
[subject] 1 - 260 (931)
 1e-40 171   41%
Product
Putative regulatory protein AfsR-like protein
Gene
SCLAV_0462
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
91
 E2D2K1_9BACT
(E2D2K1)		 
[query] 1 - 250 (272)
[subject] 6 - 255 (258)
 3e-40 169   40%
Product
Pathway specific transcriptional regulator
Gene
 
Organism
uncultured soil bacterium
1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]
92
 C7N0E0_SACVD
(C7N0E0)		 
[query] 1 - 253 (272)
[subject] 1 - 250 (631)
 3e-40 169   41%
Product
DNA-binding transcriptional activator of the SARP family
Gene
Svir_33780
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
93
 B0LJ06_9ACTO
(B0LJ06)		 
[query] 1 - 263 (272)
[subject] 1 - 261 (625)
 3e-40 169   43%
Product
Lct23
Gene
lct23
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
94
 O68913_9ACTO
(O68913)		 Jump to Fren_00070 
[query] 1 - 250 (272)
[subject] 1 - 251 (282)
 1e-39 167   44%
Product
Pathway specific regulator
Gene
frnG
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
96
 D2BBI6_STRRD
(D2BBI6)		 
[query] 1 - 256 (272)
[subject] 15 - 263 (378)
 2e-39 167   39%
Product
Transcriptional regulator, SARP family
Gene
Sros_1211
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
99
 Q7WT17_9ACTO
(Q7WT17)		 Jump to Medem_00250 
[query] 1 - 250 (272)
[subject] 1 - 248 (258)
 2e-38 164   41%
Product
Pathway-specific transcriptional activator (SARP)
Gene
med-ORF11
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
100
 Q0RI37_FRAAA
(Q0RI37)		 
[query] 1 - 256 (272)
[subject] 4 - 256 (456)
 2e-38 163   39%
Product
Putative transcriptional regulator
Gene
FRAAL4193
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]