BLAST table : Polk_00050

	accession	DB	alignment	Evalue	Score	Ident.	link	product	gene	organism	ec
1	C0JWA0_9ACTO (C0JWA0)			0.0	722	100%	UniProt GenBank	PokGT2	pokGT2	Streptomyces diastatochromogenes
2	D7BZS5_STRBB (D7BZS5)			5e-60	236	43%	UniProt GenBank	IroB	SBI_06860	Streptomyces bingchenggensis (strain BCW-1)
3	E5RLN7_9ACTO (E5RLN7)			8e-57	225	37%	UniProt GenBank	Putative glycosyltransferase	pnxGT2	Streptomyces sp. TA-0256
4	D7BZS3_STRBB (D7BZS3)			1e-54	218	40%	UniProt GenBank	Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B	SBI_06858	Streptomyces bingchenggensis (strain BCW-1)
5	D7BZR2_STRBB (D7BZR2)			4e-54	216	44%	UniProt GenBank	Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B	SBI_06847	Streptomyces bingchenggensis (strain BCW-1)
6	A4GV88_9ACTO (A4GV88)			1e-52	212	38%	UniProt GenBank	Glycosyltransferase	holL	Streptomyces sp. Tu1156
7	Q2HR28_9ACTO (Q2HR28)			5e-52	209	39%	UniProt GenBank	Putative O-glycosyltransferase	schS9	Streptomyces sp. SCC 2136
8	Q9ZGB8_STRCY (Q9ZGB8)			9e-51	205	39%	UniProt GenBank	Glycosyl transferase homolog	lanGT1	Streptomyces cyanogenus
9	C4NYL0_9ACTO (C4NYL0)			6e-50	202	38%	UniProt GenBank	SaqGT3	saqGT3	Micromonospora sp. Tu 6368
10	C4NYL1_9ACTO (C4NYL1)			8e-48	196	39%	UniProt GenBank	SaqGT4	saqGT4	Micromonospora sp. Tu 6368
11	Q4JHR2_9PSEU (Q4JHR2)			1e-47	195	37%	UniProt GenBank	BusG	busG	Saccharopolyspora pogona
12	Q9ALM8_9PSEU (Q9ALM8)			2e-47	194	37%	UniProt GenBank	Probable NDP-rhamnosyltransferase	spnG	Saccharopolyspora spinosa
13	Q9RP99_STRFR (Q9RP99)			2e-47	194	38%	UniProt GenBank	Glycosyl transferase	urdGT1c	Streptomyces fradiae Streptomyces roseoflavus
14	Q9RPA1_STRFR (Q9RPA1)			3e-46	190	37%	UniProt GenBank	Glycosyl transferase	urdGT1b	Streptomyces fradiae Streptomyces roseoflavus
15	Q6QR18_STRGL (Q6QR18)			1e-45	188	41%	UniProt GenBank	Glycosyl transferase		Streptomyces globisporus
16	A4GV86_9ACTO (A4GV86)			2e-42	177	36%	UniProt GenBank	Glycosyltransferase	holA	Streptomyces sp. FU107
17	D8I4K4_AMYMU (D8I4K4)			2e-40	171	35%	UniProt GenBank	Putative glycosyl transferase	AMED_5418	Amycolatopsis mediterranei (strain U-32)
18	A4FK43_SACEN (A4FK43)			3e-40	171	37%	UniProt GenBank	Putative glycosyl transferase, related to UDP-glucuronosyltransferase	iroB SACE_5174	Saccharopolyspora erythraea (strain NRRL 23338)
19	Q9ZGB4_STRCY (Q9ZGB4)			7e-40	169	38%	UniProt GenBank	Glycosyl transferase homolog	lanGT3	Streptomyces cyanogenus
20	E8S036_MICSL (E8S036)			6e-39	166	39%	UniProt GenBank	Putative uncharacterized protein	ML5_4680	Micromonospora sp. (strain L5)
21	Q70J67_STRGR (Q70J67)			1e-38	165	37%	UniProt GenBank	Glycosyltransferase	cmmGII	Streptomyces griseus subsp. griseus
22	D8I4I4_AMYMU (D8I4I4)			2e-38	164	33%	UniProt GenBank	Putative glycosyl transferase	AMED_5398	Amycolatopsis mediterranei (strain U-32)
23	D9SZA9_MICAI (D9SZA9)			5e-38	163	39%	UniProt GenBank	Putative uncharacterized protein	Micau_3719	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
24	B5L6L8_MICCH (B5L6L8)			4e-37	160	33%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
25	D1GLU2_9ACTO (D1GLU2)			4e-37	160	34%	UniProt GenBank	Glycosyltransferase	slgG	Streptomyces lydicus
26	Q4R0L9_STRCX (Q4R0L9)			4e-37	160	37%	UniProt GenBank	ChaGT1 protein	chaGT1	Streptomyces chartreusis
27	C0JWA3_9ACTO (C0JWA3)			4e-37	160	36%	UniProt GenBank	PokGT1	pokGT1	Streptomyces diastatochromogenes
28	B3TMP7_9ACTO (B3TMP7)			3e-36	157	35%	UniProt GenBank	Glycosyltransferase	KijC3	Actinomadura kijaniata
29	D2AY79_STRRD (D2AY79)			3e-36	157	38%	UniProt GenBank	IroB	Sros_4185	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
30	D8I4K0_AMYMU (D8I4K0)			6e-36	156	34%	UniProt GenBank	Putative glycosyl transferase	AMED_5414	Amycolatopsis mediterranei (strain U-32)
31	D7BZR5_STRBB (D7BZR5)			9e-36	155	36%	UniProt GenBank	Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B	SBI_06850	Streptomyces bingchenggensis (strain BCW-1)
32	Q194P9_STRAA (Q194P9)			2e-35	155	35%	UniProt GenBank	Glycosyltransferase	mtmGIII	Streptomyces argillaceus
33	B5L6J8_MICCH (B5L6J8)			3e-35	154	34%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
34	D8HZA4_AMYMU (D8HZA4)			6e-35	153	35%	UniProt GenBank	DNTP-hexose glycosyl transferase	AMED_0639	Amycolatopsis mediterranei (strain U-32)
35	O52563_AMYMD (O52563)			6e-35	153	35%	UniProt GenBank	Putative dNTP-hexose glycosyltransferase		Amycolatopsis mediterranei Nocardia mediterranei
36	Q70J70_STRGR (Q70J70)			2e-34	151	37%	UniProt GenBank	Glycosyltransferase	cmmGIII	Streptomyces griseus subsp. griseus
37	A4F7H2_SACEN (A4F7H2)			3e-34	150	34%	UniProt GenBank	Putative glucosyltransferase	iroB SACE_0652	Saccharopolyspora erythraea (strain NRRL 23338)	2.4.1.- niceE keggE
38	Q70J68_STRGR (Q70J68)			5e-34	150	33%	UniProt GenBank	Glycosyltransferase	cmmGIV	Streptomyces griseus subsp. griseus
39	Q0H2X6_9ACTO (Q0H2X6)			7e-34	149	33%	UniProt GenBank	Putative O-glycosyltransferase	atG1	Actinomadura melliaura
40	Q2P9Y9_9ACTO (Q2P9Y9)			7e-34	149	33%	UniProt GenBank	Glycosyl transferase	stfG	Streptomyces steffisburgensis
41	Q2HR56_9ACTO (Q2HR56)			1e-33	148	33%	UniProt GenBank	Putative C-glycosyltransferase	schS7	Streptomyces sp. SCC 2136
42	A4F7N6_SACEN (A4F7N6)			8e-33	146	33%	UniProt GenBank	6-DEB TDP-mycarosyl glycosyltransferase	eryBV SACE_0719	Saccharopolyspora erythraea (strain NRRL 23338)
43	O33939_SACER (O33939)			8e-33	146	33%	UniProt GenBank	EryBV Putative glycosyltransferase	eryBV EryBV	Saccharopolyspora erythraea Streptomyces erythraeus
44	B3TMP5_9ACTO (B3TMP5)			3e-32	144	32%	UniProt GenBank	Glycosyltransferase	KijC1	Actinomadura kijaniata
45	E8RWS4_MICSL (E8RWS4)			3e-32	144	31%	UniProt GenBank	Putative uncharacterized protein	ML5_4413	Micromonospora sp. (strain L5)
46	D9T2A5_MICAI (D9T2A5)			3e-32	144	31%	UniProt GenBank	Putative uncharacterized protein	Micau_4008	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
47	Q194Q0_STRAA (Q194Q0)			4e-32	143	32%	UniProt GenBank	Glycosyltransferase	mtmGIV	Streptomyces argillaceus
48	D9VBX2_9ACTO (D9VBX2)			6e-32	143	32%	UniProt GenBank	Putative uncharacterized protein	SSMG_03360	Streptomyces sp. AA4
49	B3TMN6_9ACTO (B3TMN6)			6e-32	143	32%	UniProt GenBank	Glycosyltransferase	KijA4	Actinomadura kijaniata
50	Q8GHC2_9ACTO (Q8GHC2)			1e-31	142	36%	UniProt GenBank	Glycosyltransferase	cloM	Streptomyces roseochromogenes subsp. oscitans
51	Q70J80_STRGR (Q70J80)			2e-31	141	32%	UniProt GenBank	Glycosyltransferase	cmmGI	Streptomyces griseus subsp. griseus
52	Q0R4P9_STRAT (Q0R4P9)			2e-31	141	33%	UniProt GenBank	ChlC7		Streptomyces antibioticus
53	D6AXN2_9ACTO (D6AXN2)			6e-31	139	30%	UniProt GenBank	RdmH	SSHG_05324	Streptomyces albus J1074
54	B5G890_9ACTO (B5G890)			7e-31	139	29%	UniProt GenBank	Glycosyltransferase family 28 domain-containing protein	SSBG_00498	Streptomyces sp. SPB74
55	E5L4T5_9ACTO (E5L4T5)			8e-31	139	29%	UniProt GenBank	Glycosyltransferase		Streptomyces sp. SCSIO 01934
56	D1H0I8_9ACTO (D1H0I8)			1e-30	139	34%	UniProt GenBank	Putative C-glycosyltransferase	ravGT	Streptomyces sp. C23201NS3
57	D7AZA6_NOCDD (D7AZA6)			1e-30	138	33%	UniProt GenBank	Putative uncharacterized protein	Ndas_4700	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
58	E3IZG9_FRASU (E3IZG9)			1e-30	138	34%	UniProt GenBank	Putative uncharacterized protein	FraEuI1c_4748	Frankia sp. (strain EuI1c)
59	A8WDM7_9ACTO (A8WDM7)			3e-30	137	32%	UniProt GenBank	Glycosyltransferase		Streptomyces eurythermus
60	B5L6L9_MICCH (B5L6L9)			5e-30	136	36%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
61	Q52V43_9ACTO (Q52V43)			7e-30	136	37%	UniProt GenBank	Glycosyltransferase		Streptomyces aizunensis
62	E3IV35_FRASU (E3IV35)			7e-30	136	32%	UniProt GenBank	Putative uncharacterized protein	FraEuI1c_2005	Frankia sp. (strain EuI1c)
63	A8Y8I2_STRAM (A8Y8I2)			8e-30	136	37%	UniProt GenBank	Putative glycosyltransferase	srm18	Streptomyces ambofaciens
64	C4NYM1_9ACTO (C4NYM1)			1e-29	135	33%	UniProt GenBank	SaqGT6	saqGT6	Micromonospora sp. Tu 6368
65	D6MSX4_9ACTO (D6MSX4)			1e-29	135	33%	UniProt GenBank	SsfS6	ssfS6	Streptomyces sp. SF2575
66	D7AZB3_NOCDD (D7AZB3)			1e-29	135	32%	UniProt GenBank	Putative uncharacterized protein	Ndas_4707	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
67	E0KQM6_STRVO (E0KQM6)			2e-29	135	29%	UniProt GenBank	Putative uncharacterized protein	StrviDRAFT_4953	Streptomyces violaceusniger Tu 4113
68	Q9F832_9ACTO (Q9F832)			2e-29	134	32%	UniProt GenBank	TDP-mycarose glycosyltransferase	megBV	Micromonospora megalomicea subsp. nigra
69	Q9L555_9ACTO (Q9L555)			5e-29	133	27%	UniProt GenBank	AknK	aknK	Streptomyces galilaeus
70	A7DWJ3_STRTE (A7DWJ3)			7e-29	132	37%	UniProt GenBank	Putative inactive gylcosyltransferase	llpG	Streptomyces tendae
71	Q8VWB7_9ACTO (Q8VWB7)			8e-29	132	28%	UniProt GenBank	AclK	aclK	Streptomyces galilaeus
72	Q9F839_9ACTO (Q9F839)			1e-28	132	28%	UniProt GenBank	TDP-megosamine glycosyltransferase	megDI	Micromonospora megalomicea subsp. nigra
73	Q194P5_STRAA (Q194P5)			1e-28	132	36%	UniProt GenBank	Glycosyltransferase	mtmGI	Streptomyces argillaceus
74	Q93KW3_STRVR (Q93KW3)			2e-28	131	32%	UniProt GenBank	Putative glycosyltransferase	aviGT1	Streptomyces viridochromogenes
75	Q0R4N0_STRAT (Q0R4N0)			3e-28	130	32%	UniProt GenBank	ChlC6		Streptomyces antibioticus
76	D9T2A9_MICAI (D9T2A9)			3e-28	130	29%	UniProt GenBank	Putative uncharacterized protein	Micau_4012	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
77	O87831_STRAT (O87831)			4e-28	130	30%	UniProt GenBank	Glycosyltransferase	oleG2	Streptomyces antibioticus
78	C4NCL8_9ACTO (C4NCL8)			8e-28	129	33%	UniProt GenBank	Rhamnosyltransferase	cpz31	Streptomyces sp. MK730-62F2
79	B0LJ53_9ACTO (B0LJ53)			9e-28	129	30%	UniProt GenBank	Lcz36	lcz36	Streptomyces sanglieri
80	D6AXP3_9ACTO (D6AXP3)			9e-28	129	32%	UniProt GenBank	C-glycosyltransferase SaqGT5	SSHG_05335	Streptomyces albus J1074
81	Q194P6_STRAA (Q194P6)			1e-27	129	32%	UniProt GenBank	Glycosyltransferase	mtmGII	Streptomyces argillaceus
82	A1C188_9ACTO (A1C188)			1e-27	128	31%	UniProt GenBank	L-rhamnosyltransferase		Streptomyces echinatus
83	P95747_STRFR (P95747)			1e-27	128	33%	UniProt GenBank	Glycosyltransferase	tylMII(orf2*)	Streptomyces fradiae Streptomyces roseoflavus
84	Q2I780_9ACTO (Q2I780)			2e-27	128	33%	UniProt GenBank	PlaA6	plaA6 STTU_1431	Streptomyces sp. Tu6071
85	E8RWS3_MICSL (E8RWS3)			2e-27	128	30%	UniProt GenBank	Putative uncharacterized protein	ML5_4412	Micromonospora sp. (strain L5)
86	Q76KZ6_STRHA (Q76KZ6)			2e-27	128	29%	UniProt GenBank	Glycosyltransferase	vinC	Streptomyces halstedii
87	A4GV85_9ACTO (A4GV85)			2e-27	128	30%	UniProt GenBank	Glycosyltransferase	holC	Streptomyces rufochromogenes
88	B0LJ19_9ACTO (B0LJ19)			2e-27	128	28%	UniProt GenBank	Lct36	lct36	Streptomyces rishiriensis
89	C4RP72_9ACTO (C4RP72)			2e-27	127	31%	UniProt GenBank	Glycosyl transferase	MCAG_03635	Micromonospora sp. ATCC 39149
90	C4NYL6_9ACTO (C4NYL6)			2e-27	127	32%	UniProt GenBank	SaqGT5	saqGT5	Micromonospora sp. Tu 6368
91	Q9RIP9_STRNO (Q9RIP9)			3e-27	127	33%	UniProt GenBank	SnogZ	snogZ	Streptomyces nogalater
92	D7B009_NOCDD (D7B009)			3e-27	127	32%	UniProt GenBank	Putative uncharacterized protein	Ndas_4711	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
93	D9T2A6_MICAI (D9T2A6)			4e-27	127	30%	UniProt GenBank	Putative uncharacterized protein	Micau_4009	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
94	D6AT98_STRFL (D6AT98)			4e-27	127	30%	UniProt GenBank	AknK	SSGG_05542	Streptomyces roseosporus NRRL 15998
95	D5UX47_TSUPD (D5UX47)			6e-27	126	31%	UniProt GenBank	Putative uncharacterized protein	Tpau_3487	Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) Corynebacterium paurometabolum
96	D8I4J7_AMYMU (D8I4J7)			6e-27	126	35%	UniProt GenBank	Putative glycosyl transferase	AMED_5411	Amycolatopsis mediterranei (strain U-32)
97	A8M6E3_SALAI (A8M6E3)			7e-27	126	31%	UniProt GenBank	Putative uncharacterized protein	Sare_1263	Salinispora arenicola (strain CNS-205)
98	Q9L9F5_STRSH (Q9L9F5)			7e-27	126	34%	UniProt GenBank	NovM	novM	Streptomyces spheroides Streptomyces caeruleus
99	Q83X73_STRRO (Q83X73)			7e-27	126	29%	UniProt GenBank	Glycosyltransferase LkmI	lkmI	Streptomyces rochei Streptomyces parvullus
100	D7BZT2_STRBB (D7BZT2)			2e-26	125	33%	UniProt GenBank	IroB	SBI_06867	Streptomyces bingchenggensis (strain BCW-1)

	accession	DB	alignment	Evalue	Score	Ident.	link	information	pubmed
1	C0JWA0_9ACTO (C0JWA0)			0.0	722	100%	UniProt GenBank	Product PokGT2 Gene pokGT2 Organism Streptomyces diastatochromogenes	1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
2	D7BZS5_STRBB (D7BZS5)			5e-60	236	43%	UniProt GenBank	Product IroB Gene SBI_06860 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
4	D7BZS3_STRBB (D7BZS3)			1e-54	218	40%	UniProt GenBank	Product Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B Gene SBI_06858 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
5	D7BZR2_STRBB (D7BZR2)			4e-54	216	44%	UniProt GenBank	Product Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B Gene SBI_06847 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6	A4GV88_9ACTO (A4GV88)			1e-52	212	38%	UniProt GenBank	Product Glycosyltransferase Gene holL Organism Streptomyces sp. Tu1156	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
7	Q2HR28_9ACTO (Q2HR28)			5e-52	209	39%	UniProt GenBank	Product Putative O-glycosyltransferase Gene schS9 Organism Streptomyces sp. SCC 2136	1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
8	Q9ZGB8_STRCY (Q9ZGB8)			9e-51	205	39%	UniProt GenBank	Product Glycosyl transferase homolog Gene lanGT1 Organism Streptomyces cyanogenus	1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
9	C4NYL0_9ACTO (C4NYL0)			6e-50	202	38%	UniProt GenBank	Product SaqGT3 Gene saqGT3 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
10	C4NYL1_9ACTO (C4NYL1)			8e-48	196	39%	UniProt GenBank	Product SaqGT4 Gene saqGT4 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
11	Q4JHR2_9PSEU (Q4JHR2)			1e-47	195	37%	UniProt GenBank	Product BusG Gene busG Organism Saccharopolyspora pogona	1uniprot[Pubmed] 16179985 Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
12	Q9ALM8_9PSEU (Q9ALM8)			2e-47	194	37%	UniProt GenBank	Product Probable NDP-rhamnosyltransferase Gene spnG Organism Saccharopolyspora spinosa	1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
13	Q9RP99_STRFR (Q9RP99)			2e-47	194	38%	UniProt GenBank	Product Glycosyl transferase Gene urdGT1c Organism Streptomyces fradiae Streptomyces roseoflavus	1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
14	Q9RPA1_STRFR (Q9RPA1)			3e-46	190	37%	UniProt GenBank	Product Glycosyl transferase Gene urdGT1b Organism Streptomyces fradiae Streptomyces roseoflavus	1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
15	Q6QR18_STRGL (Q6QR18)			1e-45	188	41%	UniProt GenBank	Product Glycosyl transferase Gene   Organism Streptomyces globisporus	1uniprot[Pubmed] 15123249 Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004]
16	A4GV86_9ACTO (A4GV86)			2e-42	177	36%	UniProt GenBank	Product Glycosyltransferase Gene holA Organism Streptomyces sp. FU107	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
17	D8I4K4_AMYMU (D8I4K4)			2e-40	171	35%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5418 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
18	A4FK43_SACEN (A4FK43)			3e-40	171	37%	UniProt GenBank	Product Putative glycosyl transferase, related to UDP-glucuronosyltransferase Gene iroB SACE_5174 Organism Saccharopolyspora erythraea (strain NRRL 23338)	1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
19	Q9ZGB4_STRCY (Q9ZGB4)			7e-40	169	38%	UniProt GenBank	Product Glycosyl transferase homolog Gene lanGT3 Organism Streptomyces cyanogenus	1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
22	D8I4I4_AMYMU (D8I4I4)			2e-38	164	33%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5398 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
24	B5L6L8_MICCH (B5L6L8)			4e-37	160	33%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
25	D1GLU2_9ACTO (D1GLU2)			4e-37	160	34%	UniProt GenBank	Product Glycosyltransferase Gene slgG Organism Streptomyces lydicus	1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
26	Q4R0L9_STRCX (Q4R0L9)			4e-37	160	37%	UniProt GenBank	Product ChaGT1 protein Gene chaGT1 Organism Streptomyces chartreusis	1uniprot[Pubmed] 15911378 Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
27	C0JWA3_9ACTO (C0JWA3)			4e-37	160	36%	UniProt GenBank	Product PokGT1 Gene pokGT1 Organism Streptomyces diastatochromogenes	1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
28	B3TMP7_9ACTO (B3TMP7)			3e-36	157	35%	UniProt GenBank	Product Glycosyltransferase Gene KijC3 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
29	D2AY79_STRRD (D2AY79)			3e-36	157	38%	UniProt GenBank	Product IroB Gene Sros_4185 Organism Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)	1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
30	D8I4K0_AMYMU (D8I4K0)			6e-36	156	34%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5414 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
31	D7BZR5_STRBB (D7BZR5)			9e-36	155	36%	UniProt GenBank	Product Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B Gene SBI_06850 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
32	Q194P9_STRAA (Q194P9)			2e-35	155	35%	UniProt GenBank	Product Glycosyltransferase Gene mtmGIII Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
33	B5L6J8_MICCH (B5L6J8)			3e-35	154	34%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
34	D8HZA4_AMYMU (D8HZA4)			6e-35	153	35%	UniProt GenBank	Product DNTP-hexose glycosyl transferase Gene AMED_0639 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
35	O52563_AMYMD (O52563)			6e-35	153	35%	UniProt GenBank	Product Putative dNTP-hexose glycosyltransferase Gene   Organism Amycolatopsis mediterranei Nocardia mediterranei	1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] [pubmed all]
37	A4F7H2_SACEN (A4F7H2)			3e-34	150	34%	UniProt GenBank	Product Putative glucosyltransferase Gene iroB SACE_0652 Organism Saccharopolyspora erythraea (strain NRRL 23338)	1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
39	Q0H2X6_9ACTO (Q0H2X6)			7e-34	149	33%	UniProt GenBank	Product Putative O-glycosyltransferase Gene atG1 Organism Actinomadura melliaura	1uniprot[Pubmed] 16873021 Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]
40	Q2P9Y9_9ACTO (Q2P9Y9)			7e-34	149	33%	UniProt GenBank	Product Glycosyl transferase Gene stfG Organism Streptomyces steffisburgensis	1uniprot[Pubmed] 16751529 Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
41	Q2HR56_9ACTO (Q2HR56)			1e-33	148	33%	UniProt GenBank	Product Putative C-glycosyltransferase Gene schS7 Organism Streptomyces sp. SCC 2136	1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
42	A4F7N6_SACEN (A4F7N6)			8e-33	146	33%	UniProt GenBank	Product 6-DEB TDP-mycarosyl glycosyltransferase Gene eryBV SACE_0719 Organism Saccharopolyspora erythraea (strain NRRL 23338)	1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
43	O33939_SACER (O33939)			8e-33	146	33%	UniProt GenBank	Product EryBV Putative glycosyltransferase Gene eryBV EryBV Organism Saccharopolyspora erythraea Streptomyces erythraeus	1uniprot[Pubmed] 9353926 [Medline] 98015410 Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.(Microbiology) 2uniprot[Pubmed] 9393448 [Medline] 98055166 Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.(Mol. Gen. Genet.) [1997] [pubmed all]
44	B3TMP5_9ACTO (B3TMP5)			3e-32	144	32%	UniProt GenBank	Product Glycosyltransferase Gene KijC1 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
47	Q194Q0_STRAA (Q194Q0)			4e-32	143	32%	UniProt GenBank	Product Glycosyltransferase Gene mtmGIV Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
49	B3TMN6_9ACTO (B3TMN6)			6e-32	143	32%	UniProt GenBank	Product Glycosyltransferase Gene KijA4 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
50	Q8GHC2_9ACTO (Q8GHC2)			1e-31	142	36%	UniProt GenBank	Product Glycosyltransferase Gene cloM Organism Streptomyces roseochromogenes subsp. oscitans	1uniprot[Pubmed] 12480894 [Medline] 22368916 Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002]
52	Q0R4P9_STRAT (Q0R4P9)			2e-31	141	33%	UniProt GenBank	Product ChlC7 Gene   Organism Streptomyces antibioticus	1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
57	D7AZA6_NOCDD (D7AZA6)			1e-30	138	33%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4700 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
60	B5L6L9_MICCH (B5L6L9)			5e-30	136	36%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
61	Q52V43_9ACTO (Q52V43)			7e-30	136	37%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Streptomyces aizunensis	1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
63	A8Y8I2_STRAM (A8Y8I2)			8e-30	136	37%	UniProt GenBank	Product Putative glycosyltransferase Gene srm18 Organism Streptomyces ambofaciens	1uniprot Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
64	C4NYM1_9ACTO (C4NYM1)			1e-29	135	33%	UniProt GenBank	Product SaqGT6 Gene saqGT6 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
65	D6MSX4_9ACTO (D6MSX4)			1e-29	135	33%	UniProt GenBank	Product SsfS6 Gene ssfS6 Organism Streptomyces sp. SF2575	1uniprot[Pubmed] 19908837 Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
66	D7AZB3_NOCDD (D7AZB3)			1e-29	135	32%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4707 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
68	Q9F832_9ACTO (Q9F832)			2e-29	134	32%	UniProt GenBank	Product TDP-mycarose glycosyltransferase Gene megBV Organism Micromonospora megalomicea subsp. nigra	1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
69	Q9L555_9ACTO (Q9L555)			5e-29	133	27%	UniProt GenBank	Product AknK Gene aknK Organism Streptomyces galilaeus	1uniprot[Pubmed] 12137949 [Medline] 22133312 Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
70	A7DWJ3_STRTE (A7DWJ3)			7e-29	132	37%	UniProt GenBank	Product Putative inactive gylcosyltransferase Gene llpG Organism Streptomyces tendae	1uniprot Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
71	Q8VWB7_9ACTO (Q8VWB7)			8e-29	132	28%	UniProt GenBank	Product AclK Gene aclK Organism Streptomyces galilaeus	1uniprot[Pubmed] 12399480 [Medline] 22286521 Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
72	Q9F839_9ACTO (Q9F839)			1e-28	132	28%	UniProt GenBank	Product TDP-megosamine glycosyltransferase Gene megDI Organism Micromonospora megalomicea subsp. nigra	1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
73	Q194P5_STRAA (Q194P5)			1e-28	132	36%	UniProt GenBank	Product Glycosyltransferase Gene mtmGI Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
74	Q93KW3_STRVR (Q93KW3)			2e-28	131	32%	UniProt GenBank	Product Putative glycosyltransferase Gene aviGT1 Organism Streptomyces viridochromogenes	1uniprot[Pubmed] 11410376 [Medline] 21303144 Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics.(Chem. Biol.) [2001] 2uniprot[Pubmed] 15489167 Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.(Chem. Biol.) [2004] [pubmed all]
75	Q0R4N0_STRAT (Q0R4N0)			3e-28	130	32%	UniProt GenBank	Product ChlC6 Gene   Organism Streptomyces antibioticus	1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
77	O87831_STRAT (O87831)			4e-28	130	30%	UniProt GenBank	Product Glycosyltransferase Gene oleG2 Organism Streptomyces antibioticus	1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998]
78	C4NCL8_9ACTO (C4NCL8)			8e-28	129	33%	UniProt GenBank	Product Rhamnosyltransferase Gene cpz31 Organism Streptomyces sp. MK730-62F2	1uniprot[Pubmed] 19351877 Identification and manipulation of the caprazamycin gene cluster leads to new simplified liponucleoside antibiotics and gives insights into the biosynthetic pathway.(J. Biol. Chem.) [2009]
79	B0LJ53_9ACTO (B0LJ53)			9e-28	129	30%	UniProt GenBank	Product Lcz36 Gene lcz36 Organism Streptomyces sanglieri	1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
81	Q194P6_STRAA (Q194P6)			1e-27	129	32%	UniProt GenBank	Product Glycosyltransferase Gene mtmGII Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
83	P95747_STRFR (P95747)			1e-27	128	33%	UniProt GenBank	Product Glycosyltransferase Gene tylMII(orf2*) Organism Streptomyces fradiae Streptomyces roseoflavus	1uniprot[Pubmed] 9031628 [Medline] 97183662 Analysis of four tylosin biosynthetic genes from the tylLM region of Streptomyces fradiae.(Gene) [1997]
84	Q2I780_9ACTO (Q2I780)			2e-27	128	33%	UniProt GenBank	Product PlaA6 Gene plaA6 STTU_1431 Organism Streptomyces sp. Tu6071	1uniprot[Pubmed] 16632249 Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives.(Chem. Biol.) [2006]
86	Q76KZ6_STRHA (Q76KZ6)			2e-27	128	29%	UniProt GenBank	Product Glycosyltransferase Gene vinC Organism Streptomyces halstedii	1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
87	A4GV85_9ACTO (A4GV85)			2e-27	128	30%	UniProt GenBank	Product Glycosyltransferase Gene holC Organism Streptomyces rufochromogenes	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
88	B0LJ19_9ACTO (B0LJ19)			2e-27	128	28%	UniProt GenBank	Product Lct36 Gene lct36 Organism Streptomyces rishiriensis	1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
90	C4NYL6_9ACTO (C4NYL6)			2e-27	127	32%	UniProt GenBank	Product SaqGT5 Gene saqGT5 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
91	Q9RIP9_STRNO (Q9RIP9)			3e-27	127	33%	UniProt GenBank	Product SnogZ Gene snogZ Organism Streptomyces nogalater	1uniprot[Pubmed] 8668120 [Medline] 96242142 A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996] 2uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] 3uniprot[Pubmed] 8760909 [Medline] 96349102 Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996] [pubmed all]
92	D7B009_NOCDD (D7B009)			3e-27	127	32%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4711 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
96	D8I4J7_AMYMU (D8I4J7)			6e-27	126	35%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5411 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
98	Q9L9F5_STRSH (Q9L9F5)			7e-27	126	34%	UniProt GenBank	Product NovM Gene novM Organism Streptomyces spheroides Streptomyces caeruleus	1uniprot[Pubmed] 10770754 [Medline] 20233587 Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000]
99	Q83X73_STRRO (Q83X73)			7e-27	126	29%	UniProt GenBank	Product Glycosyltransferase LkmI Gene lkmI Organism Streptomyces rochei Streptomyces parvullus	1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] [pubmed all]
100	D7BZT2_STRBB (D7BZT2)			2e-26	125	33%	UniProt GenBank	Product IroB Gene SBI_06867 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]