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Rule : Glycogen debranching enzyme (GLGX)

Rule Description

ID NRULE_0139
Rule name GLGX
Created 2013-02-14
Protein name
Protein name
Full
Glycogen debranching enzyme
EC
EC 3.2.1.-
Synonym
Full
Glycogen operon protein GlgX
Gene name glgX
Rule Trigger TIGRFAMs; TIGR02100; hit=1
Cross Reference
Gene Ontology
GO
GO:0004135, F:amylo-alpha-1,6-glucosidase activity, IDA:EcoCyc
GO:0043169, F:cation binding, IEA:InterPro
GO:0005980, P:glycogen catabolic process, IEA:UniProtKB-UniPathway
GO:0006974, P:response to DNA damage stimulus, IEP:EcoliWiki
Phylogenomic databases
eggNOG
COG1523, -
HOGENOM
HOG000239197, -
KO
K02438, -
Enzyme and pathway databases
UniPathway
UPA00165, -
Family and domain databases
InterPro
IPR006047, Glyco_hydro_13_cat_dom
IPR004193, Glyco_hydro_13_N
IPR011837, Glycogen_debranch_debranch
Pfam
PF00128, Alpha-amylase, 1
PF02922, CBM_48, 1
TIGRFAMs
TIGR02100, glgX_debranch, 1
Feature
P15067 Escherichia coli (strain K12).
ACT_SITE336Nucleophile (By similarity).
ACT_SITE371Proton donor (By similarity).
SITE443Transition state stabilizer (By similarity).
General annotation
Function
Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen
Pathway
Glycan degradation; glycogen degradation
Sequence similarities
Belongs to the glycosyl hydrolase 13 family
Reference
P15067 Escherichia coli (strain K12).
8576033
Coordinate genetic regulation of glycogen catabolism and biosynthesis in Escherichia coli via the CsrA gene product. (J Bacteriol. 1996)
Q9LC80 Arthrobacter sp. (strain Q36).
10669803
Cloning and nucleotide sequence of a gene encoding a glycogen debranching enzyme in the trehalose operon from Arthrobacter sp. Q36. (Biochim Biophys Acta. 2000)



Related Function

Function name
Trehalose biosynthesis (from maltooligosaccharide)

CDS

Data Download
Scientific name NBRC No. CDS Product name
Acetobacter pasteurianus105190APA32_20830Glycogen debranching enzyme GlgX
Acetobacter pasteurianus101655APT_1916glycogen debranching enzyme GlgX
Acetobacter tropicalis101654ATPR_1604glycogen debranching enzyme GlgX
Acidiphilium multivorum100883ACMV_32760glycogen debranching enzyme
Acidobacterium capsulatum15755ACP_0709glycogen debranching enzyme GlgX
Actinoplanes missouriensis102363AMIS_48070putative glycogen debranching enzyme
AMIS_60130putative glycogen debranching enzyme
AMIS_63900putative glycogen debranching enzyme
Actinosynnema mirum14064Amir_5114glycogen debranching enzyme GlgX
Amir_6067glycogen debranching enzyme GlgX
Alteromonas macleodii102226MASE_11145glycogen debranching protein GlgX
Amycolatopsis mediterranei13415RAM_13170glycogen debranching enzyme GlgX
RAM_13185glycogen debranching enzyme GlgX
RAM_15565glycogen debranching enzyme GlgX
Anaerolinea thermophila100420ANT_05210glycogen debranching enzyme
Arcanobacterium haemolyticum15585Arch_0391glycogen debranching enzyme GlgX
Arch_0802glycogen debranching enzyme GlgX
Arthrobacter globiformis12137ARGLB_047_00070glycogen debranching enzyme
ARGLB_080_00680glycogen debranching enzyme
ARGLB_085_03220glycogen debranching enzyme
Austwickia chelonae105200AUCHE_02_00130glycogen debranching enzyme
AUCHE_05_01990glycogen debranching enzyme
Azorhizobium caulinodans14845AZC_2750glycogen debranching protein
Beutenbergia cavernae16432Bcav_1345glycogen debranching enzyme GlgX
Bcav_1973glycogen debranching enzyme GlgX
Bradyrhizobium diazoefficiens14792blr6769glycogen debranching enzyme
Candidatus Solibacter usitatusAcid_0219glycogen debranching enzyme GlgX
Acid_2891glycogen debranching enzyme GlgX
Acid_7170glycogen debranching enzyme GlgX
Cellulomonas fimi15513Celf_2110glycogen debranching enzyme GlgX
Celf_2759glycogen debranching enzyme GlgX
Cellulomonas flavigena3775Cfla_1101glycogen debranching enzyme GlgX
Cfla_1743glycogen debranching enzyme GlgX
Chitinispirillum alkaliphilumCHISP_3327Glycogen debranching enzyme
Chitinophaga pinensis15968Cpin_2576glycogen debranching enzyme GlgX
Chthoniobacter flavusCfE428DRAFT_1822glycogen debranching enzyme GlgX
CfE428DRAFT_4836glycogen debranching enzyme GlgX
CfE428DRAFT_5239glycogen debranching enzyme GlgX
CfE428DRAFT_6123glycogen debranching enzyme GlgX
Corynebacterium ammoniagenes12612HMPREF0281_00079glycogen debranching enzyme GlgX
Corynebacterium callunae15359H924_08870hypothetical protein
Corynebacterium efficiens100395CE2010putative glycogen debranching enzyme
Corynebacterium glutamicum12168Cgl2107Pullulanase and related glycosidases
Corynebacterium glutamicum12153KIQ_09011hypothetical protein
Corynebacterium matruchotii15360HMPREF0299_6786glycogen debranching enzyme GlgX
Corynebacterium striatum15291HMPREF0308_0996glycogen debranching enzyme GlgX
Corynebacterium terpenotabidum14764A606_02980glycogen debranching protein
Cystobacter fuscus100088D187_000195Glycogen debranching enzyme
D187_010281Glycogen debranching enzyme
Deinococcus proteolyticus101906Deipr_0622glycogen debranching enzyme GlgX
Edwardsiella tarda105688ET1_13_00230glycogen debranching enzyme
Enterobacter aerogenes13534EAE_05390glycogen debranching enzyme
Enterobacter cloacae subsp. cloacae13535ECL_01951glycogen debranching enzyme GlgX
ECL_04793glycogen debranching enzyme
Enterobacter hormaechei105718HMPREF9086_2406glycogen debranching enzyme GlgX
HMPREF9086_4261glycogen debranching enzyme GlgX
Escherichia coli3972EcolC_0281glycogen debranching enzyme GlgX
Escherichia coli13500WFL_18035glycogen debranching enzyme
Escherichia coli12713Y75_3790glycogen debranching enzyme
Escherichia fergusonii102419EFER_3408glycogen debranching enzyme
Escherichia hermannii105704EH105704_07_00840glycogen debranching enzyme
EH105704_10_00880glycogen debranching enzyme
Fischerella sp.PCC9339_RS0107460hypothetical protein
PCC9339_RS0119465hypothetical protein
PCC9339_RS0133210glycogen debranching protein
Gemmata obscuriglobusGEMOB_RS12450glycogen debranching protein
GEMOB_RS28385glycogen-debranching protein
Geodermatophilus obscurus13315Gobs_1958glycogen debranching enzyme GlgX
Gobs_4097glycogen debranching enzyme GlgX
Gluconacetobacter hansenii14816GXY_08055glycogen debranching enzyme GlgX
GXY_09794glycogen debranching enzyme GlgX
Gluconobacter frateurii101659GfraN1_010100009262glycogen debranching protein GlgX
Gordonia aichiensis108223GOACH_16_01140glycogen debranching enzyme
GOACH_58_01030glycogen debranching enzyme
Gordonia alkanivorans16433GOALK_084_00170glycogen debranching enzyme
Gordonia amarae15530GOAMR_40_00010glycogen debranching enzyme
Gordonia amicalis100051GOAMI_54_00170glycogen debranching enzyme
Gordonia bronchialis16047Gbro_2978glycogen debranching enzyme GlgX
Gordonia effusa100432GOEFS_065_00060glycogen debranching enzyme
Gordonia namibiensis108229GONAM_46_00180glycogen debranching enzyme
Gordonia otitidis100426GOOTI_065_00610glycogen debranching enzyme
GOOTI_099_00100glycogen debranching enzyme
Gordonia polyisoprenivorans16320GOPIP_059_00020glycogen debranching enzyme
Gordonia rhizosphera16068GORHZ_053_00330glycogen debranching enzyme
GORHZ_073_00200glycogen debranching enzyme TreX
Gordonia rubripertincta101908GORBP_068_00520glycogen debranching enzyme
Gordonia soli108243GS4_30_00690glycogen debranching enzyme
Gordonia sputi100414GOSPT_058_00850glycogen debranching enzyme
GOSPT_072_00120glycogen debranching enzyme
Gordonia terrae100016GOTRE_063_00300glycogen debranching enzyme
Intrasporangium calvum12989Intca_1349isoamylase
Intca_2397glycogen debranching enzyme GlgX
Jonesia denitrificans15587Jden_1726glycogen debranching enzyme GlgX
Kineococcus radiotolerans101839Krad_1306glycogen debranching enzyme GlgX
Krad_3073glycogen debranching enzyme GlgX
Krad_3835glycogen debranching enzyme GlgX
Kineosphaera limosa100340KILIM_011_00480glycogen debranching enzyme
KILIM_025_00350putative glycogen debranching enzyme
Kitasatospora setae14216KSE_20060putative glycogen debranching enzyme
KSE_50810putative glycogen debranching enzyme
Klebsiella pneumoniae14438KPR_5120
Klebsiella pneumoniae subsp. rhinoscleromatis105682HMPREF0484_0751glycogen debranching enzyme GlgX
Kocuria rhizophila103217KRH_06550glycogen debranching enzyme
KRH_18670putative glycogen debranching enzyme
Kribbella flavida14399Kfla_0736glycogen debranching enzyme GlgX
Kfla_4935glycogen debranching enzyme GlgX
Kytococcus sedentarius15357Ksed_09570glycogen debranching enzyme GlgX
Magnetospirillum gryphiswaldense15271MGR_0453Glycoside hydrolase, family 13, N-terminal:Alpha amylase, catalytic region
Magnetospirillum magnetotacticum15272Magn03009875COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases
Marinomonas mediterranea103028Marme_3129glycogen debranching enzyme GlgX
Methylacidiphilum infernorumMinf_0536Type II secretory pathway, pullulanase PulA or related glycosidase
Methylobacterium radiotolerans15690Mrad2831_1151glycogen debranching enzyme GlgX
Mrad2831_1486glycogen debranching enzyme GlgX
Micrococcus luteus3333Mlut_16760glycogen debranching enzyme GlgX
Microlunatus phosphovorus101784MLP_29690glycogen debranching enzyme
MLP_36670glycogen debranching enzyme
Micromonospora aurantiaca16155Micau_2849glycogen debranching enzyme GlgX
Mobilicoccus pelagius104925MOPEL_036_00100glycogen debranching enzyme
MOPEL_130_00060glycogen debranching enzyme
Nakamurella multipartita105858Namu_2795glycogen debranching enzyme GlgX
Namu_3089glycogen debranching enzyme GlgX
Niastella koreensis106392Niako_3122glycogen debranching enzyme GlgX
Nitriliruptor alkaliphilusNitalDRAFT_3915glycogen operon protein
Nitrospina gracilisNITGR_290078Glycogen debranching enzyme GlgX
Nocardiopsis dassonvillei14626Ndas_2820glycogen debranching enzyme GlgX
Pelobacter propionicus103807Ppro_0419isoamylase
Photobacterium damselae subsp. damselae corrig.15633VDA_002815glycogen debranching enzyme
Planctomyces brasiliensis103401Plabr_2631isoamylase
Propionibacterium acidipropionici12425PACID_19100Glycogen debranching enzyme GlgX
Propionibacterium avidum15671HMPREF9153_1838glycogen debranching enzyme GlgX
Providencia alcalifaciens105687PROVALCAL_01516glycogen debranching enzyme GlgX
Pseudomonas putida100650PP_4055glycogen operon protein GlgX
Pseudomonas stutzeri14165PSTAB_2030glycogen operon protein GlgX
Rahnella aquatilis105701Rahaq2_0227glycogen debranching enzyme GlgX
Rahaq2_2353glycogen debranching enzyme GlgX
Renibacterium salmoninarum15589RSal33209_0413isoamylase
RSal33209_1717isoamylase
Rhizobium etli15573RHE_CH03598glycosyl hydrolase (glycogen debranching) protein
RHE_PE00208glycosyl hydrolase (glycogen debranching) protein
Rhizobium sp.101917NGR_b11120glycogen operon-like protein GlgX
NGR_c28990glycosyl hydrolase
Rhizobium tropici15247RTCIAT899_CH15315glycogen debranching enzyme GlgX
Rhodobacter capsulatus16581RCAP_rcc01838glycogen debranching enzyme GlgX
Rhodobacter sphaeroides12203RSP_2226Glycosidase
RSP_2449Putative glycosyl hydrolase
RSP_2884glycogen debranching enzyme
Rhodococcus erythropolis100887RER_23610probable glycogen debranching enzyme
RER_35060probable glycogen debranching enzyme
Rhodococcus opacus108011ROP_07840glycogen debranching enzyme
ROP_65030glycogen debranching enzyme
Roseobacter denitrificans15277RD1_2872glycogen debranching enzyme
Roseobacter litoralis15278RLO149_c015680glycogen debranching enzyme
Rubrobacter xylanophilus100952Rxyl_0317Glycogen debranching enzyme GlgX
Saccharothrix espanaensis15066BN6_61820Glycogen operon protein, GlgX family
BN6_72710Glycogen operon protein, GlgX family
Salinibacter ruberSRU_0849glycogen debranching enzyme GlgX
Sanguibacter keddieii16158Sked_10400glycogen debranching enzyme GlgX
Sked_16660glycogen debranching enzyme GlgX
Serratia odorifera102598HMPREF0758_1063glycogen debranching enzyme GlgX
Shimwellia blattae105725EB105725_06_00150glycogen debranching enzyme
Sphingobium japonicum101211SJA_C1-21930glycogen operon protein GlgX
Sphingobium sp.103272SLG_08630glycogen debranching enzyme
SLG_10410glycogen debranching enzyme
Sporichthya polymorpha12702Spopo_30_18120Putative glycogen debranching enzyme
Spopo_31_11050Isoamylase
Spopo_31_15840Glycogen debranching enzyme
Starkeya novella14993Snov_2556glycogen debranching enzyme GlgX
Snov_4184glycogen debranching enzyme GlgX
Streptomyces avermitilis14893SAV2151putative glycogen debranching enzyme
SAV2789putative glycosyl hydrolase
Streptomyces cattleya14057SCAT_4262Glycogen operon protein glgX homolog
SCAT_4716Glycogen operon protein glgX homolog
SCAT_p1240Glycogen operon protein glgX homolog
Streptomyces clavuligerus13307SCLAV_4880Glycogen debranching enzyme
Streptomyces ghanaensis15414SSFG_01617glycogen debranching enzyme
SSFG_02235glycogen debranching enzyme
SSFG_06481glycogen debranching enzyme
Streptomyces mobaraensis13819H340_21661glycogen debranching protein
H340_29479glycosyl hydrolase
Streptomyces pristinaespiralis13074SSDG_00715glycogen debranching enzyme
SSDG_05563glycogen debranching enzyme
Streptomyces purpureus13925STRPU_14_02590Glycogen debranching enzyme
STRPU_16_03320Glycogen debranching enzyme
Streptomyces sviceus13980SSEG_00594glycogen debranching enzyme GlgX
SSEG_07982glycogen debranching enzyme GlgX
SSEG_10504glycogen debranching enzyme GlgX
Streptomyces venezuelae13096SVEN_5112Glycogen debranching enzyme
SVEN_5898Glycogen debranching enzyme
Streptosporangium roseum3776Sros_1601glycogen debranching protein GlgX
Sros_6707glycogen debranching protein GlgX
Sulfolobus tokodaii100140STK_09280glycogen debranching enzyme TreX
Synechococcus elongatusSynpcc7942_0086isoamylase, glycosyl hydrolase family 13
Synechocystis sp.slr0237glycogen operon protein; GlgX
slr1857glycogen operon protein; GlgX
Thauera linaloolentis102519C666_19020glycogen debranching protein GlgX
Thermobispora bispora14880Tbis_2253glycogen debranching enzyme GlgX
Thermomonospora curvata15933Tcur_1775glycogen debranching enzyme GlgX
Thermotoga lettingae107922Tlet_0139glycogen debranching enzyme GlgX
Thermotoga thermarum107925Theth_1308isoamylase
Tsukamurella paurometabola16120Tpau_2939glycogen debranching enzyme GlgX
Vibrio alginolyticus15630N646_3360glycogen operon protein GlgX
Vibrio ichthyoenteri15847VII00023_11926type II secretory pathway, pullulanase
Vibrio metschnikovii103153VIB_002522glycogen debranching enzyme
Vibrio orientalis15638VIOR3934_20606Isoamylase
Vibrio tubiashii15644VITU9109_15193Isoamylase
Vibrio vulnificus15645B736_13970glycogen-debranching protein
Xenococcus sp.Xen7305DRAFT_00004430glycogen debranching enzyme GlgX
Xen7305DRAFT_00036400glycogen debranching enzyme GlgX
Xen7305DRAFT_00039940glycogen debranching enzyme GlgX
Xylanimonas cellulosilytica107835Xcel_2413glycogen debranching enzyme GlgX
Yersinia bercovieri105717yberc0001_3530Glycogen debranching enzyme
Yersinia rohdei105715yrohd0001_13520Glycogen debranching enzyme
Zimmermannella faecalis15706G328_10005hypothetical protein
G328_10150hypothetical protein