BLAST table : Spino_00150

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q9ALM8_9PSEU
(Q9ALM8)
[query] 1 - 390 (390)
[subject] 1 - 390 (390)
0.0 783   100% Probable NDP-rhamnosyltransferase spnG Saccharopolyspora spinosa
2
Q4JHR2_9PSEU
(Q4JHR2)
[query] 1 - 390 (390)
[subject] 1 - 390 (390)
0.0 734   94% BusG busG Saccharopolyspora pogona
3
D7BZS5_STRBB
(D7BZS5)
[query] 1 - 387 (390)
[subject] 1 - 388 (405)
2e-68 264   42% IroB SBI_06860 Streptomyces bingchenggensis (strain BCW-1)
4
D7BZS3_STRBB
(D7BZS3)
[query] 1 - 386 (390)
[subject] 1 - 390 (395)
3e-67 260   41% Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B SBI_06858 Streptomyces bingchenggensis (strain BCW-1)
5
E5RLN7_9ACTO
(E5RLN7)
[query] 1 - 387 (390)
[subject] 1 - 386 (388)
1e-63 248   39% Putative glycosyltransferase pnxGT2 Streptomyces sp. TA-0256
6
Q9ZGB8_STRCY
(Q9ZGB8)
Jump to Lando_00220
[query] 1 - 389 (390)
[subject] 1 - 390 (390)
2e-63 248   39% Glycosyl transferase homolog lanGT1 Streptomyces cyanogenus
7
A4GV88_9ACTO
(A4GV88)
[query] 1 - 384 (390)
[subject] 1 - 386 (388)
8e-59 232   37% Glycosyltransferase holL Streptomyces sp. Tu1156
8
C4NYL0_9ACTO
(C4NYL0)
[query] 1 - 386 (390)
[subject] 1 - 393 (404)
3e-58 230   38% SaqGT3 saqGT3 Micromonospora sp. Tu 6368
9
Q2HR28_9ACTO
(Q2HR28)
Jump to Sch475_00300
[query] 1 - 386 (390)
[subject] 1 - 387 (390)
3e-55 220   35% Putative O-glycosyltransferase schS9 Streptomyces sp. SCC 2136
10
Q9RPA1_STRFR
(Q9RPA1)
Jump to Urd_00040
[query] 1 - 388 (390)
[subject] 1 - 388 (388)
2e-53 214   36% Glycosyl transferase urdGT1b Streptomyces fradiae
Streptomyces roseoflavus
11
C4NYL1_9ACTO
(C4NYL1)
[query] 1 - 384 (390)
[subject] 1 - 389 (396)
4e-53 213   38% SaqGT4 saqGT4 Micromonospora sp. Tu 6368
12
Q6QR18_STRGL
(Q6QR18)
[query] 1 - 387 (390)
[subject] 1 - 388 (389)
7e-53 213   39% Glycosyl transferase Streptomyces globisporus
13
Q9ZGB4_STRCY
(Q9ZGB4)
Jump to Lando_00260
[query] 1 - 384 (390)
[subject] 1 - 394 (401)
7e-51 206   38% Glycosyl transferase homolog lanGT3 Streptomyces cyanogenus
14
Q9RP99_STRFR
(Q9RP99)
Jump to Urd_00060
[query] 1 - 388 (390)
[subject] 1 - 387 (391)
1e-50 205   36% Glycosyl transferase urdGT1c Streptomyces fradiae
Streptomyces roseoflavus
15
A4GV86_9ACTO
(A4GV86)
[query] 1 - 384 (390)
[subject] 1 - 387 (389)
8e-48 196   35% Glycosyltransferase holA Streptomyces sp. FU107
16
C0JWA0_9ACTO
(C0JWA0)
Jump to Polk_00050
[query] 1 - 387 (390)
[subject] 1 - 377 (382)
2e-47 194   37% PokGT2 pokGT2 Streptomyces diastatochromogenes
17
Q70J80_STRGR
(Q70J80)
Jump to Chro_00180
[query] 1 - 385 (390)
[subject] 1 - 382 (393)
5e-45 186   34% Glycosyltransferase cmmGI Streptomyces griseus subsp. griseus
18
Q9L9F5_STRSH
(Q9L9F5)
[query] 1 - 382 (390)
[subject] 1 - 369 (379)
8e-44 182   36% NovM novM Streptomyces spheroides
Streptomyces caeruleus
19
B5L6L8_MICCH
(B5L6L8)
[query] 1 - 387 (390)
[subject] 1 - 398 (398)
2e-43 181   32% Glycosyltransferase Micromonospora chalcea
20
B3TMP5_9ACTO
(B3TMP5)
[query] 1 - 384 (390)
[subject] 1 - 399 (401)
2e-43 181   33% Glycosyltransferase KijC1 Actinomadura kijaniata
21
D7BZR2_STRBB
(D7BZR2)
[query] 1 - 389 (390)
[subject] 1 - 389 (401)
6e-43 179   35% Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B SBI_06847 Streptomyces bingchenggensis (strain BCW-1)
22
Q194P9_STRAA
(Q194P9)
Jump to Mith_00260
[query] 1 - 390 (390)
[subject] 1 - 394 (396)
2e-41 174   34% Glycosyltransferase mtmGIII Streptomyces argillaceus
23
Q70J68_STRGR
(Q70J68)
Jump to Chro_00300
[query] 1 - 386 (390)
[subject] 1 - 404 (421)
1e-40 172   34% Glycosyltransferase cmmGIV Streptomyces griseus subsp. griseus
24
B3TMP7_9ACTO
(B3TMP7)
[query] 1 - 383 (390)
[subject] 1 - 414 (417)
1e-39 168   33% Glycosyltransferase KijC3 Actinomadura kijaniata
25
Q8GHC2_9ACTO
(Q8GHC2)
[query] 1 - 382 (390)
[subject] 1 - 369 (390)
6e-39 166   35% Glycosyltransferase cloM Streptomyces roseochromogenes subsp. oscitans
26
B3TMN6_9ACTO
(B3TMN6)
[query] 1 - 389 (390)
[subject] 1 - 421 (426)
8e-39 166   32% Glycosyltransferase KijA4 Actinomadura kijaniata
27
D7BZT2_STRBB
(D7BZT2)
[query] 1 - 387 (390)
[subject] 1 - 412 (419)
3e-38 164   33% IroB SBI_06867 Streptomyces bingchenggensis (strain BCW-1)
28
D8I4K4_AMYMU
(D8I4K4)
[query] 1 - 387 (390)
[subject] 1 - 386 (392)
8e-38 162   32% Putative glycosyl transferase AMED_5418 Amycolatopsis mediterranei (strain U-32)
29
D7BZR5_STRBB
(D7BZR5)
[query] 1 - 384 (390)
[subject] 1 - 400 (402)
3e-37 160   34% Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B SBI_06850 Streptomyces bingchenggensis (strain BCW-1)
30
D6MSX4_9ACTO
(D6MSX4)
[query] 1 - 384 (390)
[subject] 1 - 382 (383)
4e-37 160   32% SsfS6 ssfS6 Streptomyces sp. SF2575
31
D8I4I4_AMYMU
(D8I4I4)
[query] 1 - 375 (390)
[subject] 1 - 374 (389)
1e-36 159   32% Putative glycosyl transferase AMED_5398 Amycolatopsis mediterranei (strain U-32)
32
B5L6L9_MICCH
(B5L6L9)
[query] 1 - 342 (390)
[subject] 1 - 377 (379)
4e-36 157   32% Glycosyltransferase Micromonospora chalcea
33
B3TMP8_9ACTO
(B3TMP8)
[query] 1 - 387 (390)
[subject] 1 - 397 (397)
5e-36 156   33% Glycosyltransferase KijC4 Actinomadura kijaniata
34
D2AY79_STRRD
(D2AY79)
[query] 1 - 383 (390)
[subject] 1 - 373 (382)
5e-36 156   37% IroB Sros_4185 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
35
C0JWA3_9ACTO
(C0JWA3)
Jump to Polk_00080
[query] 1 - 375 (390)
[subject] 1 - 387 (397)
1e-35 155   33% PokGT1 pokGT1 Streptomyces diastatochromogenes
36
Q9F8U7_9ACTO
(Q9F8U7)
[query] 1 - 382 (390)
[subject] 1 - 380 (402)
1e-35 155   34% Glycosyl transferase couM Streptomyces rishiriensis
37
D8I4K0_AMYMU
(D8I4K0)
[query] 1 - 382 (390)
[subject] 1 - 372 (377)
4e-35 153   32% Putative glycosyl transferase AMED_5414 Amycolatopsis mediterranei (strain U-32)
38
Q70J70_STRGR
(Q70J70)
Jump to Chro_00280
[query] 1 - 386 (390)
[subject] 1 - 393 (397)
5e-35 153   31% Glycosyltransferase cmmGIII Streptomyces griseus subsp. griseus
39
Q0R4N0_STRAT
(Q0R4N0)
Jump to Chth_00240
[query] 3 - 389 (390)
[subject] 1 - 403 (404)
8e-35 152   31% ChlC6 Streptomyces antibioticus
40
D9SZA9_MICAI
(D9SZA9)
[query] 10 - 386 (390)
[subject] 6 - 382 (387)
1e-34 152   34% Putative uncharacterized protein Micau_3719 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
41
O87831_STRAT
(O87831)
[query] 1 - 387 (390)
[subject] 1 - 413 (426)
4e-34 150   32% Glycosyltransferase oleG2 Streptomyces antibioticus
42
E8S036_MICSL
(E8S036)
[query] 10 - 386 (390)
[subject] 6 - 382 (387)
1e-33 149   34% Putative uncharacterized protein ML5_4680 Micromonospora sp. (strain L5)
43
Q67G38_9ACTO
(Q67G38)
Jump to Heda_00200
[query] 1 - 389 (390)
[subject] 1 - 379 (379)
5e-33 146   32% Glycosyltransferase Streptomyces griseoruber
44
A4F7H2_SACEN
(A4F7H2)
[query] 1 - 385 (390)
[subject] 1 - 377 (383)
5e-33 146   33% Putative glucosyltransferase iroB
SACE_0652
Saccharopolyspora erythraea (strain NRRL 23338) 2.4.1.-
45
D6AXN2_9ACTO
(D6AXN2)
[query] 1 - 387 (390)
[subject] 1 - 420 (426)
6e-33 146   29% RdmH SSHG_05324 Streptomyces albus J1074
46
Q0R4P9_STRAT
(Q0R4P9)
Jump to Chth_00050
[query] 1 - 387 (390)
[subject] 1 - 406 (411)
7e-33 146   31% ChlC7 Streptomyces antibioticus
47
Q70J67_STRGR
(Q70J67)
Jump to Chro_00310
[query] 1 - 386 (390)
[subject] 1 - 377 (396)
2e-32 144   33% Glycosyltransferase cmmGII Streptomyces griseus subsp. griseus
48
D8I4J9_AMYMU
(D8I4J9)
[query] 1 - 371 (390)
[subject] 1 - 368 (386)
4e-32 144   33% Putative glycosyl transferase AMED_5413 Amycolatopsis mediterranei (strain U-32)
49
C4NYM1_9ACTO
(C4NYM1)
[query] 1 - 387 (390)
[subject] 1 - 409 (416)
4e-32 143   30% SaqGT6 saqGT6 Micromonospora sp. Tu 6368
50
C4NCL8_9ACTO
(C4NCL8)
[query] 1 - 386 (390)
[subject] 1 - 393 (396)
4e-32 143   33% Rhamnosyltransferase cpz31 Streptomyces sp. MK730-62F2
51
E3IZG9_FRASU
(E3IZG9)
[query] 1 - 387 (390)
[subject] 1 - 381 (382)
5e-32 143   33% Putative uncharacterized protein FraEuI1c_4748 Frankia sp. (strain EuI1c)
52
D8I4J7_AMYMU
(D8I4J7)
[query] 1 - 341 (390)
[subject] 1 - 348 (400)
7e-32 142   30% Putative glycosyl transferase AMED_5411 Amycolatopsis mediterranei (strain U-32)
53
Q194P5_STRAA
(Q194P5)
Jump to Mith_00300
[query] 1 - 384 (390)
[subject] 1 - 377 (393)
1e-31 142   30% Glycosyltransferase mtmGI Streptomyces argillaceus
54
Q9F832_9ACTO
(Q9F832)
Jump to Megalo_00100
[query] 1 - 386 (390)
[subject] 1 - 410 (417)
5e-31 140   31% TDP-mycarose glycosyltransferase megBV Micromonospora megalomicea subsp. nigra
55
E4N0M1_KITSK
(E4N0M1)
[query] 1 - 389 (390)
[subject] 1 - 376 (377)
5e-31 140   31% Putative glycosyltransferase KSE_59350 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
56
A8Y8I2_STRAM
(A8Y8I2)
[query] 1 - 384 (390)
[subject] 3 - 377 (394)
6e-31 139   32% Putative glycosyltransferase srm18 Streptomyces ambofaciens
57
A4FK43_SACEN
(A4FK43)
[query] 1 - 386 (390)
[subject] 1 - 355 (365)
1e-30 138   30% Putative glycosyl transferase, related to UDP-glucuronosyltransferase iroB
SACE_5174
Saccharopolyspora erythraea (strain NRRL 23338)
58
D4QF41_9ACTO
(D4QF41)
[query] 1 - 379 (390)
[subject] 1 - 386 (397)
2e-30 138   31% Rhamnosyltransferase lipB1 Streptomyces sp. SANK 60405
59
D1A6T1_THECD
(D1A6T1)
[query] 1 - 387 (390)
[subject] 1 - 377 (380)
2e-30 138   31% Putative uncharacterized protein Tcur_2790 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
60
D8I4J6_AMYMU
(D8I4J6)
[query] 1 - 375 (390)
[subject] 1 - 380 (397)
3e-30 137   31% Putative glycosyl transferase AMED_5410 Amycolatopsis mediterranei (strain U-32)
61
Q2I780_9ACTO
(Q2I780)
[query] 1 - 387 (390)
[subject] 1 - 392 (396)
6e-30 136   30% PlaA6 plaA6
STTU_1431
Streptomyces sp. Tu6071
62
D8I4K8_AMYMU
(D8I4K8)
[query] 1 - 383 (390)
[subject] 1 - 366 (370)
9e-30 135   36% Putative glycosyl transferase AMED_5422 Amycolatopsis mediterranei (strain U-32)
63
B5L6J8_MICCH
(B5L6J8)
[query] 1 - 386 (390)
[subject] 1 - 388 (392)
1e-29 135   31% Glycosyltransferase Micromonospora chalcea
64
A4GV89_9ACTO
(A4GV89)
[query] 1 - 387 (390)
[subject] 1 - 413 (415)
2e-29 134   30% Glycosyltransferase holN Streptomyces sp. FU107
65
D1GLU2_9ACTO
(D1GLU2)
Jump to Strply_00140
[query] 1 - 382 (390)
[subject] 1 - 386 (391)
2e-29 134   30% Glycosyltransferase slgG Streptomyces lydicus
66
Q2HR56_9ACTO
(Q2HR56)
Jump to Sch475_00280
[query] 1 - 384 (390)
[subject] 1 - 376 (378)
5e-29 133   31% Putative C-glycosyltransferase schS7 Streptomyces sp. SCC 2136
67
B0LJ53_9ACTO
(B0LJ53)
[query] 1 - 387 (390)
[subject] 1 - 423 (427)
1e-28 132   30% Lcz36 lcz36 Streptomyces sanglieri
68
D9VBX2_9ACTO
(D9VBX2)
[query] 1 - 389 (390)
[subject] 1 - 417 (418)
2e-28 131   29% Putative uncharacterized protein SSMG_03360 Streptomyces sp. AA4
69
A8WDM7_9ACTO
(A8WDM7)
[query] 1 - 389 (390)
[subject] 1 - 422 (424)
2e-28 131   30% Glycosyltransferase Streptomyces eurythermus
70
Q935Z8_9ACTO
(Q935Z8)
[query] 1 - 387 (390)
[subject] 1 - 416 (428)
3e-28 130   30% RdmH rdmH Streptomyces purpurascens
71
D7AZA5_NOCDD
(D7AZA5)
[query] 1 - 386 (390)
[subject] 1 - 415 (417)
3e-28 130   28% Putative uncharacterized protein Ndas_4699 Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
72
P95747_STRFR
(P95747)
[query] 1 - 388 (390)
[subject] 21 - 440 (452)
3e-28 130   30% Glycosyltransferase tylMII(orf2*) Streptomyces fradiae
Streptomyces roseoflavus
73
Q4R0L9_STRCX
(Q4R0L9)
Jump to Chart_00130
[query] 1 - 373 (390)
[subject] 1 - 364 (382)
4e-28 130   31% ChaGT1 protein chaGT1 Streptomyces chartreusis
74
Q9ALN7_9PSEU
(Q9ALN7)
Jump to Spino_00060
[query] 1 - 389 (390)
[subject] 17 - 443 (455)
4e-28 130   30% Probable NDP-forosamyltransferase spnP Saccharopolyspora spinosa
75
A7DWJ3_STRTE
(A7DWJ3)
[query] 1 - 369 (390)
[subject] 1 - 357 (378)
5e-28 130   33% Putative inactive gylcosyltransferase llpG Streptomyces tendae
76
A0ACI7_STRAM
(A0ACI7)
[query] 1 - 387 (390)
[subject] 1 - 412 (418)
5e-28 130   28% Putative glycosyltransferase SAMR0481 Streptomyces ambofaciens ATCC 23877
77
E3IV35_FRASU
(E3IV35)
[query] 1 - 387 (390)
[subject] 1 - 415 (416)
2e-27 128   29% Putative uncharacterized protein FraEuI1c_2005 Frankia sp. (strain EuI1c)
78
Q9ZGH7_9ACTO
(Q9ZGH7)
Jump to Pikro_00090
[query] 1 - 387 (390)
[subject] 1 - 415 (426)
2e-27 128   28% Glycosyl transferase desVII Streptomyces venezuelae
79
E8RWS3_MICSL
(E8RWS3)
[query] 1 - 389 (390)
[subject] 1 - 435 (435)
2e-27 128   30% Putative uncharacterized protein ML5_4412 Micromonospora sp. (strain L5)
80
Q0H2X6_9ACTO
(Q0H2X6)
[query] 1 - 384 (390)
[subject] 1 - 395 (400)
2e-27 128   29% Putative O-glycosyltransferase atG1 Actinomadura melliaura
81
D9T2A6_MICAI
(D9T2A6)
[query] 1 - 389 (390)
[subject] 1 - 435 (435)
3e-27 127   30% Putative uncharacterized protein Micau_4009 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
82
Q83WE1_MICGR
(Q83WE1)
[query] 1 - 383 (390)
[subject] 1 - 411 (428)
3e-27 127   29% Glycosyltransferase mycB Micromonospora griseorubida
83
Q5SFB5_STRBI
(Q5SFB5)
Jump to Chalc_00270
[query] 1 - 384 (390)
[subject] 1 - 416 (425)
3e-27 127   28% Putative chalcose glycosyltransferase chmCIII Streptomyces bikiniensis
84
B3TMR7_9ACTO
(B3TMR7)
[query] 1 - 383 (390)
[subject] 1 - 386 (391)
3e-27 127   30% Glycosyltransferase KijD9 Actinomadura kijaniata
85
D8HZA4_AMYMU
(D8HZA4)
[query] 1 - 384 (390)
[subject] 1 - 375 (381)
3e-27 127   29% DNTP-hexose glycosyl transferase AMED_0639 Amycolatopsis mediterranei (strain U-32)
86
O52563_AMYMD
(O52563)
Jump to Rifam_00430
[query] 1 - 384 (390)
[subject] 1 - 375 (381)
3e-27 127   29% Putative dNTP-hexose glycosyltransferase Amycolatopsis mediterranei
Nocardia mediterranei
87
D7AZB3_NOCDD
(D7AZB3)
[query] 1 - 387 (390)
[subject] 1 - 423 (428)
4e-27 127   30% Putative uncharacterized protein Ndas_4707 Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
88
D1H0B4_9ACTO
(D1H0B4)
[query] 1 - 386 (390)
[subject] 1 - 377 (379)
4e-27 127   31% Putative C-glycosyltransferase chryGT Streptomyces albaduncus
89
A8Y8F5_STRAM
(A8Y8F5)
[query] 1 - 388 (390)
[subject] 1 - 417 (421)
5e-27 126   28% Probable glycosyltransferase srm3*c Streptomyces ambofaciens
90
B5G890_9ACTO
(B5G890)
[query] 1 - 387 (390)
[subject] 1 - 424 (440)
7e-27 126   28% Glycosyltransferase family 28 domain-containing protein SSBG_00498 Streptomyces sp. SPB74
91
Q6T1C7_STRGL
(Q6T1C7)
[query] 1 - 387 (390)
[subject] 1 - 412 (416)
7e-27 126   29% Glycosyltransferase LndGT4 Streptomyces globisporus
92
Q9RN63_STRNO
(Q9RN63)
Jump to Nogl_00160
[query] 1 - 384 (390)
[subject] 1 - 414 (432)
7e-27 126   31% Putative glycosyl transferase snogE Streptomyces nogalater
93
Q331Q0_9ACTO
(Q331Q0)
[query] 1 - 384 (390)
[subject] 1 - 416 (425)
9e-27 125   28% Chalcosyltransferase gerTII Streptomyces sp. KCTC 0041BP
94
Q8KRX7_9ACTO
(Q8KRX7)
[query] 1 - 387 (390)
[subject] 1 - 415 (426)
1e-26 125   29% NbmD nbmD Streptomyces narbonensis
95
Q0PY15_STRMY
(Q0PY15)
[query] 1 - 388 (390)
[subject] 1 - 417 (421)
1e-26 125   29% Glycosyltransferase midI Streptomyces mycarofaciens
96
Q9L555_9ACTO
(Q9L555)
Jump to Acla_00030
[query] 1 - 387 (390)
[subject] 1 - 424 (440)
1e-26 125   29% AknK aknK Streptomyces galilaeus
97
B4VEK6_9ACTO
(B4VEK6)
[query] 1 - 384 (390)
[subject] 1 - 416 (425)
2e-26 125   27% Chalcosyltransferase SSAG_06216 Streptomyces sp. Mg1
98
E8RWS4_MICSL
(E8RWS4)
[query] 1 - 389 (390)
[subject] 1 - 419 (420)
2e-26 124   29% Putative uncharacterized protein ML5_4413 Micromonospora sp. (strain L5)
99
D9T2A5_MICAI
(D9T2A5)
[query] 1 - 389 (390)
[subject] 1 - 419 (420)
2e-26 124   29% Putative uncharacterized protein Micau_4008 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
100
A4F7N6_SACEN
(A4F7N6)
[query] 1 - 384 (390)
[subject] 1 - 408 (415)
2e-26 124   28% 6-DEB TDP-mycarosyl glycosyltransferase eryBV
SACE_0719
Saccharopolyspora erythraea (strain NRRL 23338)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9ALM8_9PSEU
(Q9ALM8)
[query] 1 - 390 (390)
[subject] 1 - 390 (390)
0.0 783   100%
Product
Probable NDP-rhamnosyltransferase
Gene
spnG
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
2
Q4JHR2_9PSEU
(Q4JHR2)
[query] 1 - 390 (390)
[subject] 1 - 390 (390)
0.0 734   94%
Product
BusG
Gene
busG
Organism
Saccharopolyspora pogona
1uniprot[Pubmed] 16179985
Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
3
D7BZS5_STRBB
(D7BZS5)
[query] 1 - 387 (390)
[subject] 1 - 388 (405)
2e-68 264   42%
Product
IroB
Gene
SBI_06860
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
4
D7BZS3_STRBB
(D7BZS3)
[query] 1 - 386 (390)
[subject] 1 - 390 (395)
3e-67 260   41%
Product
Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
Gene
SBI_06858
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
Q9ZGB8_STRCY
(Q9ZGB8)
Jump to Lando_00220
[query] 1 - 389 (390)
[subject] 1 - 390 (390)
2e-63 248   39%
Product
Glycosyl transferase homolog
Gene
lanGT1
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
7
A4GV88_9ACTO
(A4GV88)
[query] 1 - 384 (390)
[subject] 1 - 386 (388)
8e-59 232   37%
Product
Glycosyltransferase
Gene
holL
Organism
Streptomyces sp. Tu1156
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
8
C4NYL0_9ACTO
(C4NYL0)
[query] 1 - 386 (390)
[subject] 1 - 393 (404)
3e-58 230   38%
Product
SaqGT3
Gene
saqGT3
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
9
Q2HR28_9ACTO
(Q2HR28)
Jump to Sch475_00300
[query] 1 - 386 (390)
[subject] 1 - 387 (390)
3e-55 220   35%
Product
Putative O-glycosyltransferase
Gene
schS9
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
10
Q9RPA1_STRFR
(Q9RPA1)
Jump to Urd_00040
[query] 1 - 388 (390)
[subject] 1 - 388 (388)
2e-53 214   36%
Product
Glycosyl transferase
Gene
urdGT1b
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
11
C4NYL1_9ACTO
(C4NYL1)
[query] 1 - 384 (390)
[subject] 1 - 389 (396)
4e-53 213   38%
Product
SaqGT4
Gene
saqGT4
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
12
Q6QR18_STRGL
(Q6QR18)
[query] 1 - 387 (390)
[subject] 1 - 388 (389)
7e-53 213   39%
Product
Glycosyl transferase
Gene
 
Organism
Streptomyces globisporus
1uniprot[Pubmed] 15123249
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004]
13
Q9ZGB4_STRCY
(Q9ZGB4)
Jump to Lando_00260
[query] 1 - 384 (390)
[subject] 1 - 394 (401)
7e-51 206   38%
Product
Glycosyl transferase homolog
Gene
lanGT3
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
14
Q9RP99_STRFR
(Q9RP99)
Jump to Urd_00060
[query] 1 - 388 (390)
[subject] 1 - 387 (391)
1e-50 205   36%
Product
Glycosyl transferase
Gene
urdGT1c
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
15
A4GV86_9ACTO
(A4GV86)
[query] 1 - 384 (390)
[subject] 1 - 387 (389)
8e-48 196   35%
Product
Glycosyltransferase
Gene
holA
Organism
Streptomyces sp. FU107
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
16
C0JWA0_9ACTO
(C0JWA0)
Jump to Polk_00050
[query] 1 - 387 (390)
[subject] 1 - 377 (382)
2e-47 194   37%
Product
PokGT2
Gene
pokGT2
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
18
Q9L9F5_STRSH
(Q9L9F5)
[query] 1 - 382 (390)
[subject] 1 - 369 (379)
8e-44 182   36%
Product
NovM
Gene
novM
Organism
Streptomyces spheroides
Streptomyces caeruleus
1uniprot[Pubmed] 10770754 [Medline] 20233587
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000]
19
B5L6L8_MICCH
(B5L6L8)
[query] 1 - 387 (390)
[subject] 1 - 398 (398)
2e-43 181   32%
Product
Glycosyltransferase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
20
B3TMP5_9ACTO
(B3TMP5)
[query] 1 - 384 (390)
[subject] 1 - 399 (401)
2e-43 181   33%
Product
Glycosyltransferase
Gene
KijC1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
21
D7BZR2_STRBB
(D7BZR2)
[query] 1 - 389 (390)
[subject] 1 - 389 (401)
6e-43 179   35%
Product
Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
Gene
SBI_06847
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
22
Q194P9_STRAA
(Q194P9)
Jump to Mith_00260
[query] 1 - 390 (390)
[subject] 1 - 394 (396)
2e-41 174   34%
Product
Glycosyltransferase
Gene
mtmGIII
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
24
B3TMP7_9ACTO
(B3TMP7)
[query] 1 - 383 (390)
[subject] 1 - 414 (417)
1e-39 168   33%
Product
Glycosyltransferase
Gene
KijC3
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
25
Q8GHC2_9ACTO
(Q8GHC2)
[query] 1 - 382 (390)
[subject] 1 - 369 (390)
6e-39 166   35%
Product
Glycosyltransferase
Gene
cloM
Organism
Streptomyces roseochromogenes subsp. oscitans
1uniprot[Pubmed] 12480894 [Medline] 22368916
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002]
26
B3TMN6_9ACTO
(B3TMN6)
[query] 1 - 389 (390)
[subject] 1 - 421 (426)
8e-39 166   32%
Product
Glycosyltransferase
Gene
KijA4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
27
D7BZT2_STRBB
(D7BZT2)
[query] 1 - 387 (390)
[subject] 1 - 412 (419)
3e-38 164   33%
Product
IroB
Gene
SBI_06867
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
28
D8I4K4_AMYMU
(D8I4K4)
[query] 1 - 387 (390)
[subject] 1 - 386 (392)
8e-38 162   32%
Product
Putative glycosyl transferase
Gene
AMED_5418
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
29
D7BZR5_STRBB
(D7BZR5)
[query] 1 - 384 (390)
[subject] 1 - 400 (402)
3e-37 160   34%
Product
Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
Gene
SBI_06850
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
30
D6MSX4_9ACTO
(D6MSX4)
[query] 1 - 384 (390)
[subject] 1 - 382 (383)
4e-37 160   32%
Product
SsfS6
Gene
ssfS6
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
31
D8I4I4_AMYMU
(D8I4I4)
[query] 1 - 375 (390)
[subject] 1 - 374 (389)
1e-36 159   32%
Product
Putative glycosyl transferase
Gene
AMED_5398
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
32
B5L6L9_MICCH
(B5L6L9)
[query] 1 - 342 (390)
[subject] 1 - 377 (379)
4e-36 157   32%
Product
Glycosyltransferase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
33
B3TMP8_9ACTO
(B3TMP8)
[query] 1 - 387 (390)
[subject] 1 - 397 (397)
5e-36 156   33%
Product
Glycosyltransferase
Gene
KijC4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
34
D2AY79_STRRD
(D2AY79)
[query] 1 - 383 (390)
[subject] 1 - 373 (382)
5e-36 156   37%
Product
IroB
Gene
Sros_4185
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
35
C0JWA3_9ACTO
(C0JWA3)
Jump to Polk_00080
[query] 1 - 375 (390)
[subject] 1 - 387 (397)
1e-35 155   33%
Product
PokGT1
Gene
pokGT1
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
36
Q9F8U7_9ACTO
(Q9F8U7)
[query] 1 - 382 (390)
[subject] 1 - 380 (402)
1e-35 155   34%
Product
Glycosyl transferase
Gene
couM
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 11036020 [Medline] 20493109
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000]
37
D8I4K0_AMYMU
(D8I4K0)
[query] 1 - 382 (390)
[subject] 1 - 372 (377)
4e-35 153   32%
Product
Putative glycosyl transferase
Gene
AMED_5414
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
39
Q0R4N0_STRAT
(Q0R4N0)
Jump to Chth_00240
[query] 3 - 389 (390)
[subject] 1 - 403 (404)
8e-35 152   31%
Product
ChlC6
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
41
O87831_STRAT
(O87831)
[query] 1 - 387 (390)
[subject] 1 - 413 (426)
4e-34 150   32%
Product
Glycosyltransferase
Gene
oleG2
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 9749673 [Medline] 98420102
Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998]
43
Q67G38_9ACTO
(Q67G38)
Jump to Heda_00200
[query] 1 - 389 (390)
[subject] 1 - 379 (379)
5e-33 146   32%
Product
Glycosyltransferase
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
44
A4F7H2_SACEN
(A4F7H2)
[query] 1 - 385 (390)
[subject] 1 - 377 (383)
5e-33 146   33%
Product
Putative glucosyltransferase
Gene
iroB
SACE_0652
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
46
Q0R4P9_STRAT
(Q0R4P9)
Jump to Chth_00050
[query] 1 - 387 (390)
[subject] 1 - 406 (411)
7e-33 146   31%
Product
ChlC7
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
48
D8I4J9_AMYMU
(D8I4J9)
[query] 1 - 371 (390)
[subject] 1 - 368 (386)
4e-32 144   33%
Product
Putative glycosyl transferase
Gene
AMED_5413
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
49
C4NYM1_9ACTO
(C4NYM1)
[query] 1 - 387 (390)
[subject] 1 - 409 (416)
4e-32 143   30%
Product
SaqGT6
Gene
saqGT6
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
50
C4NCL8_9ACTO
(C4NCL8)
[query] 1 - 386 (390)
[subject] 1 - 393 (396)
4e-32 143   33%
Product
Rhamnosyltransferase
Gene
cpz31
Organism
Streptomyces sp. MK730-62F2
1uniprot[Pubmed] 19351877
Identification and manipulation of the caprazamycin gene cluster leads to new simplified liponucleoside antibiotics and gives insights into the biosynthetic pathway.(J. Biol. Chem.) [2009]
52
D8I4J7_AMYMU
(D8I4J7)
[query] 1 - 341 (390)
[subject] 1 - 348 (400)
7e-32 142   30%
Product
Putative glycosyl transferase
Gene
AMED_5411
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
53
Q194P5_STRAA
(Q194P5)
Jump to Mith_00300
[query] 1 - 384 (390)
[subject] 1 - 377 (393)
1e-31 142   30%
Product
Glycosyltransferase
Gene
mtmGI
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
54
Q9F832_9ACTO
(Q9F832)
Jump to Megalo_00100
[query] 1 - 386 (390)
[subject] 1 - 410 (417)
5e-31 140   31%
Product
TDP-mycarose glycosyltransferase
Gene
megBV
Organism
Micromonospora megalomicea subsp. nigra
1uniprot[Pubmed] 10972798 [Medline] 20430101
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
55
E4N0M1_KITSK
(E4N0M1)
[query] 1 - 389 (390)
[subject] 1 - 376 (377)
5e-31 140   31%
Product
Putative glycosyltransferase
Gene
KSE_59350
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
56
A8Y8I2_STRAM
(A8Y8I2)
[query] 1 - 384 (390)
[subject] 3 - 377 (394)
6e-31 139   32%
Product
Putative glycosyltransferase
Gene
srm18
Organism
Streptomyces ambofaciens
1uniprot
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
57
A4FK43_SACEN
(A4FK43)
[query] 1 - 386 (390)
[subject] 1 - 355 (365)
1e-30 138   30%
Product
Putative glycosyl transferase, related to UDP-glucuronosyltransferase
Gene
iroB
SACE_5174
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
58
D4QF41_9ACTO
(D4QF41)
[query] 1 - 379 (390)
[subject] 1 - 386 (397)
2e-30 138   31%
Product
Rhamnosyltransferase
Gene
lipB1
Organism
Streptomyces sp. SANK 60405
1uniprot[Pubmed] 20043306
The biosynthesis of liposidomycin-like A-90289 antibiotics featuring a new type of sulfotransferase.(Chembiochem) [2010]
59
D1A6T1_THECD
(D1A6T1)
[query] 1 - 387 (390)
[subject] 1 - 377 (380)
2e-30 138   31%
Product
Putative uncharacterized protein
Gene
Tcur_2790
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
60
D8I4J6_AMYMU
(D8I4J6)
[query] 1 - 375 (390)
[subject] 1 - 380 (397)
3e-30 137   31%
Product
Putative glycosyl transferase
Gene
AMED_5410
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
61
Q2I780_9ACTO
(Q2I780)
[query] 1 - 387 (390)
[subject] 1 - 392 (396)
6e-30 136   30%
Product
PlaA6
Gene
plaA6
STTU_1431
Organism
Streptomyces sp. Tu6071
1uniprot[Pubmed] 16632249
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives.(Chem. Biol.) [2006]
62
D8I4K8_AMYMU
(D8I4K8)
[query] 1 - 383 (390)
[subject] 1 - 366 (370)
9e-30 135   36%
Product
Putative glycosyl transferase
Gene
AMED_5422
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
63
B5L6J8_MICCH
(B5L6J8)
[query] 1 - 386 (390)
[subject] 1 - 388 (392)
1e-29 135   31%
Product
Glycosyltransferase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
64
A4GV89_9ACTO
(A4GV89)
[query] 1 - 387 (390)
[subject] 1 - 413 (415)
2e-29 134   30%
Product
Glycosyltransferase
Gene
holN
Organism
Streptomyces sp. FU107
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
65
D1GLU2_9ACTO
(D1GLU2)
Jump to Strply_00140
[query] 1 - 382 (390)
[subject] 1 - 386 (391)
2e-29 134   30%
Product
Glycosyltransferase
Gene
slgG
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
66
Q2HR56_9ACTO
(Q2HR56)
Jump to Sch475_00280
[query] 1 - 384 (390)
[subject] 1 - 376 (378)
5e-29 133   31%
Product
Putative C-glycosyltransferase
Gene
schS7
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
67
B0LJ53_9ACTO
(B0LJ53)
[query] 1 - 387 (390)
[subject] 1 - 423 (427)
1e-28 132   30%
Product
Lcz36
Gene
lcz36
Organism
Streptomyces sanglieri
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
71
D7AZA5_NOCDD
(D7AZA5)
[query] 1 - 386 (390)
[subject] 1 - 415 (417)
3e-28 130   28%
Product
Putative uncharacterized protein
Gene
Ndas_4699
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
72
P95747_STRFR
(P95747)
[query] 1 - 388 (390)
[subject] 21 - 440 (452)
3e-28 130   30%
Product
Glycosyltransferase
Gene
tylMII(orf2*)
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 9031628 [Medline] 97183662
Analysis of four tylosin biosynthetic genes from the tylLM region of Streptomyces fradiae.(Gene) [1997]
73
Q4R0L9_STRCX
(Q4R0L9)
Jump to Chart_00130
[query] 1 - 373 (390)
[subject] 1 - 364 (382)
4e-28 130   31%
Product
ChaGT1 protein
Gene
chaGT1
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
74
Q9ALN7_9PSEU
(Q9ALN7)
Jump to Spino_00060
[query] 1 - 389 (390)
[subject] 17 - 443 (455)
4e-28 130   30%
Product
Probable NDP-forosamyltransferase
Gene
spnP
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
75
A7DWJ3_STRTE
(A7DWJ3)
[query] 1 - 369 (390)
[subject] 1 - 357 (378)
5e-28 130   33%
Product
Putative inactive gylcosyltransferase
Gene
llpG
Organism
Streptomyces tendae
1uniprot
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
76
A0ACI7_STRAM
(A0ACI7)
[query] 1 - 387 (390)
[subject] 1 - 412 (418)
5e-28 130   28%
Product
Putative glycosyltransferase
Gene
SAMR0481
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
78
Q9ZGH7_9ACTO
(Q9ZGH7)
Jump to Pikro_00090
[query] 1 - 387 (390)
[subject] 1 - 415 (426)
2e-27 128   28%
Product
Glycosyl transferase
Gene
desVII
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
80
Q0H2X6_9ACTO
(Q0H2X6)
[query] 1 - 384 (390)
[subject] 1 - 395 (400)
2e-27 128   29%
Product
Putative O-glycosyltransferase
Gene
atG1
Organism
Actinomadura melliaura
1uniprot[Pubmed] 16873021
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]
82
Q83WE1_MICGR
(Q83WE1)
[query] 1 - 383 (390)
[subject] 1 - 411 (428)
3e-27 127   29%
Product
Glycosyltransferase
Gene
mycB
Organism
Micromonospora griseorubida
1uniprot[Pubmed] 12583909 [Medline] 22472038
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
83
Q5SFB5_STRBI
(Q5SFB5)
Jump to Chalc_00270
[query] 1 - 384 (390)
[subject] 1 - 416 (425)
3e-27 127   28%
Product
Putative chalcose glycosyltransferase
Gene
chmCIII
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
84
B3TMR7_9ACTO
(B3TMR7)
[query] 1 - 383 (390)
[subject] 1 - 386 (391)
3e-27 127   30%
Product
Glycosyltransferase
Gene
KijD9
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
85
D8HZA4_AMYMU
(D8HZA4)
[query] 1 - 384 (390)
[subject] 1 - 375 (381)
3e-27 127   29%
Product
DNTP-hexose glycosyl transferase
Gene
AMED_0639
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
86
O52563_AMYMD
(O52563)
Jump to Rifam_00430
[query] 1 - 384 (390)
[subject] 1 - 375 (381)
3e-27 127   29%
Product
Putative dNTP-hexose glycosyltransferase
Gene
 
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
87
D7AZB3_NOCDD
(D7AZB3)
[query] 1 - 387 (390)
[subject] 1 - 423 (428)
4e-27 127   30%
Product
Putative uncharacterized protein
Gene
Ndas_4707
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
89
A8Y8F5_STRAM
(A8Y8F5)
[query] 1 - 388 (390)
[subject] 1 - 417 (421)
5e-27 126   28%
Product
Probable glycosyltransferase
Gene
srm3*c
Organism
Streptomyces ambofaciens
1uniprot
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
91
Q6T1C7_STRGL
(Q6T1C7)
[query] 1 - 387 (390)
[subject] 1 - 412 (416)
7e-27 126   29%
Product
Glycosyltransferase LndGT4
Gene
 
Organism
Streptomyces globisporus
1uniprot[Pubmed] 15123249
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004]
92
Q9RN63_STRNO
(Q9RN63)
Jump to Nogl_00160
[query] 1 - 384 (390)
[subject] 1 - 414 (432)
7e-27 126   31%
Product
Putative glycosyl transferase
Gene
snogE
Organism
Streptomyces nogalater
1uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
2uniprot[Pubmed] 10639368 [Medline] 20106987
Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000]
[pubmed all]
93
Q331Q0_9ACTO
(Q331Q0)
[query] 1 - 384 (390)
[subject] 1 - 416 (425)
9e-27 125   28%
Product
Chalcosyltransferase
Gene
gerTII
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
95
Q0PY15_STRMY
(Q0PY15)
[query] 1 - 388 (390)
[subject] 1 - 417 (421)
1e-26 125   29%
Product
Glycosyltransferase
Gene
midI
Organism
Streptomyces mycarofaciens
1uniprot[Pubmed] 17342257
Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from a midecamycin-producing strain, Streptomyces mycarofaciens.(Acta Biochim. Biophys. Sin.) [2007]
96
Q9L555_9ACTO
(Q9L555)
Jump to Acla_00030
[query] 1 - 387 (390)
[subject] 1 - 424 (440)
1e-26 125   29%
Product
AknK
Gene
aknK
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
100
A4F7N6_SACEN
(A4F7N6)
[query] 1 - 384 (390)
[subject] 1 - 408 (415)
2e-26 124   28%
Product
6-DEB TDP-mycarosyl glycosyltransferase
Gene
eryBV
SACE_0719
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]