| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
C0JWA3_9ACTO (C0JWA3) |
|
|
0.0 |
770 |
100% |
|
- Product
- PokGT1
- Gene
- pokGT1
- Organism
- Streptomyces diastatochromogenes
|
1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009] |
|
2
|
D7BZR5_STRBB (D7BZR5) |
|
|
1e-81 |
308 |
46% |
|
- Product
- Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
- Gene
- SBI_06850
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
4
|
Q194Q0_STRAA (Q194Q0) |
|
|
2e-62 |
244 |
41% |
|
- Product
- Glycosyltransferase
- Gene
- mtmGIV
- Organism
- Streptomyces argillaceus
|
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] | 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] | 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] | 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] | 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] | 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] | 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] | 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] | 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] | 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] | 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] | 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] | 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] | 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] | 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] | 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] | 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] | 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] | 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] | 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] | [pubmed all]
|
5
|
D8I4K4_AMYMU (D8I4K4) |
|
|
6e-52 |
209 |
37% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5418
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
6
|
B3TMN6_9ACTO (B3TMN6) |
|
|
1e-51 |
209 |
42% |
|
- Product
- Glycosyltransferase
- Gene
- KijA4
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
7
|
Q0H2X6_9ACTO (Q0H2X6) |
|
|
1e-48 |
198 |
37% |
|
- Product
- Putative O-glycosyltransferase
- Gene
- atG1
- Organism
- Actinomadura melliaura
|
1uniprot[Pubmed] 16873021 Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006] |
|
8
|
Q8VWB7_9ACTO (Q8VWB7) |
|
|
8e-48 |
196 |
35% |
|
- Product
- AclK
- Gene
- aclK
- Organism
- Streptomyces galilaeus
|
1uniprot[Pubmed] 12399480 [Medline] 22286521 Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002] |
|
9
|
B3TMP5_9ACTO (B3TMP5) |
|
|
1e-46 |
192 |
40% |
|
- Product
- Glycosyltransferase
- Gene
- KijC1
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
10
|
Q9L555_9ACTO (Q9L555) |
|
|
1e-46 |
192 |
35% |
|
- Product
- AknK
- Gene
- aknK
- Organism
- Streptomyces galilaeus
|
1uniprot[Pubmed] 12137949 [Medline] 22133312 Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002] |
|
11
|
D7BZS5_STRBB (D7BZS5) |
|
|
2e-46 |
191 |
37% |
|
- Product
- IroB
- Gene
- SBI_06860
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
12
|
B5L6L8_MICCH (B5L6L8) |
|
|
2e-46 |
191 |
36% |
|
- Product
- Glycosyltransferase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
14
|
D8I4I4_AMYMU (D8I4I4) |
|
|
1e-45 |
189 |
35% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5398
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
15
|
Q0R4N0_STRAT (Q0R4N0) |
|
|
2e-45 |
188 |
36% |
|
- Product
- ChlC6
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
16
|
D8I4J6_AMYMU (D8I4J6) |
|
|
3e-45 |
187 |
40% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5410
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
18
|
D7BZS3_STRBB (D7BZS3) |
|
|
4e-44 |
183 |
36% |
|
- Product
- Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
- Gene
- SBI_06858
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
19
|
D7BZT2_STRBB (D7BZT2) |
|
|
6e-44 |
182 |
37% |
|
- Product
- IroB
- Gene
- SBI_06867
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
21
|
D8I4J7_AMYMU (D8I4J7) |
|
|
2e-42 |
177 |
39% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5411
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
26
|
P95834_STRPE (P95834) |
|
|
1e-41 |
176 |
36% |
|
- Product
- Putative baumycin biosynthesis protein
- Gene
- dnrH
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 8955419 [Medline] 97113559 Enhanced antibiotic production by manipulation of the Streptomyces peucetius dnrH and dnmT genes involved in doxorubicin (adriamycin) biosynthesis.(J. Bacteriol.) [1996] | 2uniprot[Pubmed] 9864344 [Medline] 99084971 Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene.(J. Bacteriol.) [1999] | [pubmed all]
|
27
|
A4GV85_9ACTO (A4GV85) |
|
|
1e-41 |
175 |
34% |
|
- Product
- Glycosyltransferase
- Gene
- holC
- Organism
- Streptomyces rufochromogenes
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] |
|
28
|
Q83WE1_MICGR (Q83WE1) |
|
|
2e-41 |
174 |
37% |
|
- Product
- Glycosyltransferase
- Gene
- mycB
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
29
|
D8I4K0_AMYMU (D8I4K0) |
|
|
2e-41 |
174 |
35% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5414
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
30
|
B3TMP7_9ACTO (B3TMP7) |
|
|
2e-41 |
174 |
36% |
|
- Product
- Glycosyltransferase
- Gene
- KijC3
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
31
|
A4FFB3_SACEN (A4FFB3) |
|
|
3e-41 |
174 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- SACE_3464
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
32
|
Q9ZGH7_9ACTO (Q9ZGH7) |
|
|
3e-41 |
174 |
36% |
|
- Product
- Glycosyl transferase
- Gene
- desVII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
34
|
Q2P9Y9_9ACTO (Q2P9Y9) |
|
|
9e-41 |
172 |
36% |
|
- Product
- Glycosyl transferase
- Gene
- stfG
- Organism
- Streptomyces steffisburgensis
|
1uniprot[Pubmed] 16751529 Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006] |
|
35
|
Q0R4P9_STRAT (Q0R4P9) |
|
|
9e-41 |
172 |
36% |
|
- Product
- ChlC7
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
36
|
D7BZT8_STRBB (D7BZT8) |
|
|
9e-41 |
172 |
40% |
|
- Product
- Putative uncharacterized protein
- Gene
- SBI_06873
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
37
|
Q9L9F5_STRSH (Q9L9F5) |
|
|
1e-40 |
172 |
39% |
|
- Product
- NovM
- Gene
- novM
- Organism
- Streptomyces spheroides
Streptomyces caeruleus
|
1uniprot[Pubmed] 10770754 [Medline] 20233587 Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000] |
|
38
|
D2AY79_STRRD (D2AY79) |
|
|
1e-40 |
171 |
42% |
|
- Product
- IroB
- Gene
- Sros_4185
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
40
|
C4NYM1_9ACTO (C4NYM1) |
|
|
3e-40 |
171 |
36% |
|
- Product
- SaqGT6
- Gene
- saqGT6
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
41
|
Q194P9_STRAA (Q194P9) |
|
|
3e-40 |
171 |
37% |
|
- Product
- Glycosyltransferase
- Gene
- mtmGIII
- Organism
- Streptomyces argillaceus
|
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] | 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] | 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] | 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] | 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] | 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] | 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] | 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] | 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] | 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] | 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] | 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] | 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] | 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] | 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] | 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] | 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] | 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] | 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] | 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] | [pubmed all]
|
42
|
Q9F8U7_9ACTO (Q9F8U7) |
|
|
4e-40 |
170 |
38% |
|
- Product
- Glycosyl transferase
- Gene
- couM
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 11036020 [Medline] 20493109 Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000] |
|
44
|
A0ACI7_STRAM (A0ACI7) |
|
|
8e-40 |
169 |
34% |
|
- Product
- Putative glycosyltransferase
- Gene
- SAMR0481
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
46
|
Q4JHQ3_9PSEU (Q4JHQ3) |
|
|
3e-39 |
167 |
34% |
|
- Product
- BusP
- Gene
- busP
- Organism
- Saccharopolyspora pogona
|
1uniprot[Pubmed] 16179985 Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006] |
|
48
|
A4GV89_9ACTO (A4GV89) |
|
|
6e-39 |
166 |
37% |
|
- Product
- Glycosyltransferase
- Gene
- holN
- Organism
- Streptomyces sp. FU107
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] |
|
49
|
A4FK43_SACEN (A4FK43) |
|
|
6e-39 |
166 |
37% |
|
- Product
- Putative glycosyl transferase, related to UDP-glucuronosyltransferase
- Gene
- iroB
SACE_5174
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
50
|
Q93KW3_STRVR (Q93KW3) |
|
|
7e-39 |
166 |
35% |
|
- Product
- Putative glycosyltransferase
- Gene
- aviGT1
- Organism
- Streptomyces viridochromogenes
|
1uniprot[Pubmed] 11410376 [Medline] 21303144 Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 15489167 Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.(Chem. Biol.) [2004] | [pubmed all]
|
51
|
Q2PZS3_9ACTO (Q2PZS3) |
|
|
7e-39 |
166 |
35% |
|
- Product
- CosK
- Gene
- cosk
- Organism
- Streptomyces olindensis
|
1uniprot[Pubmed] 16810496 Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.(Appl. Microbiol. Biotechnol.) [2006] |
|
52
|
D7AZB3_NOCDD (D7AZB3) |
|
|
1e-38 |
166 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- Ndas_4707
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
53
|
Q9ALN7_9PSEU (Q9ALN7) |
|
|
1e-38 |
165 |
34% |
|
- Product
- Probable NDP-forosamyltransferase
- Gene
- spnP
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
54
|
Q53881_STRS5 (Q53881) |
|
|
2e-38 |
164 |
35% |
|
- Product
- Glycosyltransferase
- Gene
- dauH
- Organism
- Streptomyces sp. (strain C5)
|
1uniprot[Pubmed] 8655529 [Medline] 96236066 Cloning, sequencing, and analysis of aklaviketone reductase from Streptomyces sp. strain C5.(J. Bacteriol.) [1996] |
|
55
|
A4F7N6_SACEN (A4F7N6) |
|
|
3e-38 |
164 |
34% |
|
- Product
- 6-DEB TDP-mycarosyl glycosyltransferase
- Gene
- eryBV
SACE_0719
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
56
|
O33939_SACER (O33939) |
|
|
3e-38 |
164 |
34% |
|
- Product
- EryBV
Putative glycosyltransferase
- Gene
- eryBV
EryBV
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 9353926 [Medline] 98015410 Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.(Microbiology) | 2uniprot[Pubmed] 9393448 [Medline] 98055166 Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.(Mol. Gen. Genet.) [1997] | [pubmed all]
|
58
|
C4NCL8_9ACTO (C4NCL8) |
|
|
3e-38 |
164 |
36% |
|
- Product
- Rhamnosyltransferase
- Gene
- cpz31
- Organism
- Streptomyces sp. MK730-62F2
|
1uniprot[Pubmed] 19351877 Identification and manipulation of the caprazamycin gene cluster leads to new simplified liponucleoside antibiotics and gives insights into the biosynthetic pathway.(J. Biol. Chem.) [2009] |
|
59
|
Q9ZGB8_STRCY (Q9ZGB8) |
|
|
4e-38 |
163 |
35% |
|
- Product
- Glycosyl transferase homolog
- Gene
- lanGT1
- Organism
- Streptomyces cyanogenus
|
1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999] |
|
61
|
A4GV88_9ACTO (A4GV88) |
|
|
1e-37 |
162 |
34% |
|
- Product
- Glycosyltransferase
- Gene
- holL
- Organism
- Streptomyces sp. Tu1156
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] |
|
62
|
D7B014_NOCDD (D7B014) |
|
|
1e-37 |
162 |
35% |
|
- Product
- Putative uncharacterized protein
- Gene
- Ndas_4716
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
64
|
C0JWA0_9ACTO (C0JWA0) |
|
|
2e-37 |
161 |
36% |
|
- Product
- PokGT2
- Gene
- pokGT2
- Organism
- Streptomyces diastatochromogenes
|
1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009] |
|
67
|
P95747_STRFR (P95747) |
|
|
5e-37 |
160 |
35% |
|
- Product
- Glycosyltransferase
- Gene
- tylMII(orf2*)
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 9031628 [Medline] 97183662 Analysis of four tylosin biosynthetic genes from the tylLM region of Streptomyces fradiae.(Gene) [1997] |
|
68
|
Q54824_STRPE (Q54824) |
|
|
6e-37 |
159 |
34% |
|
- Product
- Glycosyl transferase
- Gene
- dnrS
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 7592454 [Medline] 96062261 Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis.(J. Bacteriol.) [1995] |
|
69
|
O87831_STRAT (O87831) |
|
|
6e-37 |
159 |
34% |
|
- Product
- Glycosyltransferase
- Gene
- oleG2
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998] |
|
70
|
O87830_STRAT (O87830) |
|
|
7e-37 |
159 |
34% |
|
- Product
- Glycosyltransferase
- Gene
- oleG1
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998] |
|
71
|
Q9ALM8_9PSEU (Q9ALM8) |
|
|
1e-36 |
159 |
33% |
|
- Product
- Probable NDP-rhamnosyltransferase
- Gene
- spnG
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
72
|
Q4JHR2_9PSEU (Q4JHR2) |
|
|
1e-36 |
159 |
33% |
|
- Product
- BusG
- Gene
- busG
- Organism
- Saccharopolyspora pogona
|
1uniprot[Pubmed] 16179985 Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006] |
|
73
|
B5L6L9_MICCH (B5L6L9) |
|
|
1e-36 |
158 |
36% |
|
- Product
- Glycosyltransferase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
74
|
Q83X73_STRRO (Q83X73) |
|
|
2e-36 |
158 |
31% |
|
- Product
- Glycosyltransferase LkmI
- Gene
- lkmI
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|
75
|
Q2HR28_9ACTO (Q2HR28) |
|
|
2e-36 |
158 |
32% |
|
- Product
- Putative O-glycosyltransferase
- Gene
- schS9
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
76
|
Q9F839_9ACTO (Q9F839) |
|
|
2e-36 |
158 |
34% |
|
- Product
- TDP-megosamine glycosyltransferase
- Gene
- megDI
- Organism
- Micromonospora megalomicea subsp. nigra
|
1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000] |
|
77
|
D7B009_NOCDD (D7B009) |
|
|
2e-36 |
157 |
34% |
|
- Product
- Putative uncharacterized protein
- Gene
- Ndas_4711
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
78
|
D9UBQ5_STRPR (D9UBQ5) |
|
|
4e-36 |
157 |
35% |
|
- Product
- Putative glycosyltransferase
- Gene
- cpp29
- Organism
- Streptomyces pristinaespiralis
|
1uniprot[Pubmed] 21342465 Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011] |
|
80
|
Q2HR56_9ACTO (Q2HR56) |
|
|
9e-36 |
155 |
33% |
|
- Product
- Putative C-glycosyltransferase
- Gene
- schS7
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
82
|
Q6T1C7_STRGL (Q6T1C7) |
|
|
9e-36 |
155 |
33% |
|
- Product
- Glycosyltransferase LndGT4
- Gene
-
- Organism
- Streptomyces globisporus
|
1uniprot[Pubmed] 15123249 Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004] |
|
83
|
B3TMR7_9ACTO (B3TMR7) |
|
|
1e-35 |
155 |
37% |
|
- Product
- Glycosyltransferase
- Gene
- KijD9
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
84
|
B5L6J8_MICCH (B5L6J8) |
|
|
2e-35 |
155 |
37% |
|
- Product
- Glycosyltransferase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
85
|
B3TMP8_9ACTO (B3TMP8) |
|
|
3e-35 |
154 |
38% |
|
- Product
- Glycosyltransferase
- Gene
- KijC4
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
86
|
E1ARJ9_STRAU (E1ARJ9) |
|
|
4e-35 |
153 |
35% |
|
- Product
- Putative glycosyltransferase
- Gene
- sa53
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 21393365 The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011] |
|
87
|
Q0PY15_STRMY (Q0PY15) |
|
|
9e-35 |
152 |
34% |
|
- Product
- Glycosyltransferase
- Gene
- midI
- Organism
- Streptomyces mycarofaciens
|
1uniprot[Pubmed] 17342257 Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from a midecamycin-producing strain, Streptomyces mycarofaciens.(Acta Biochim. Biophys. Sin.) [2007] |
|
88
|
A4F7P3_SACEN (A4F7P3) |
|
|
9e-35 |
152 |
33% |
|
- Product
- Glycosyl transferase, NDP-D-desosamine : 3-L-mycarosyl erythronolide B
- Gene
- eryCIII
SACE_0726
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
90
|
O33935_SACER (O33935) |
|
|
1e-34 |
152 |
33% |
|
- Product
- Desosaminyltransferase
- Gene
- eryCIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 9353926 [Medline] 98015410 Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.(Microbiology) |
|
91
|
Q8GHC2_9ACTO (Q8GHC2) |
|
|
1e-34 |
152 |
37% |
|
- Product
- Glycosyltransferase
- Gene
- cloM
- Organism
- Streptomyces roseochromogenes subsp. oscitans
|
1uniprot[Pubmed] 12480894 [Medline] 22368916 Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002] |
|
92
|
Q9RPA2_STRFR (Q9RPA2) |
|
|
2e-34 |
151 |
34% |
|
- Product
- Glycosyl transferase
- Gene
- urdGT1a
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000] |
|
93
|
D7BZR2_STRBB (D7BZR2) |
|
|
2e-34 |
151 |
37% |
|
- Product
- Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B
- Gene
- SBI_06847
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
95
|
D7B025_NOCDD (D7B025) |
|
|
1e-33 |
149 |
34% |
|
- Product
- Putative uncharacterized protein
- Gene
- Ndas_4727
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
96
|
D8I4J8_AMYMU (D8I4J8) |
|
|
1e-33 |
149 |
34% |
|
- Product
- Putative glycosyl transferase
- Gene
- AMED_5412
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
97
|
Q9RP99_STRFR (Q9RP99) |
|
|
1e-33 |
149 |
36% |
|
- Product
- Glycosyl transferase
- Gene
- urdGT1c
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000] |
|
98
|
Q2HR27_9ACTO (Q2HR27) |
|
|
1e-33 |
148 |
33% |
|
- Product
- Putative O-glycosyltransferase
- Gene
- schS10
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
99
|
Q76KZ6_STRHA (Q76KZ6) |
|
|
2e-33 |
148 |
32% |
|
- Product
- Glycosyltransferase
- Gene
- vinC
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
100
|
C4NYK7_9ACTO (C4NYK7) |
|
|
3e-33 |
147 |
32% |
|
- Product
- SaqGT1
- Gene
- saqGT1
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|