BLAST table : Rifam_00510

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 D8HZB0_AMYMU
(D8HZB0)		 
[query] 1 - 473 (473)
[subject] 1 - 473 (473)
 0.0 972   100% NDP-hexose 2,3-dehydratase AMED_0645 Amycolatopsis mediterranei (strain U-32)
2
 Q9AE03_AMYMD
(Q9AE03)		 
[query] 1 - 473 (473)
[subject] 1 - 473 (473)
 0.0 972   100% Putative 2,3-dehydratase Amycolatopsis mediterranei
Nocardia mediterranei
3
 A8M6Z0_SALAI
(A8M6Z0)		 
[query] 9 - 473 (473)
[subject] 13 - 476 (480)
 0.0 756   79% NDP-hexose 23-dehydratase Sare_1267 Salinispora arenicola (strain CNS-205)
4
 Q9RR31_STRAT
(Q9RR31)		 
[query] 16 - 473 (473)
[subject] 14 - 473 (474)
 1e-147 528   59% 2,3-dehydratase oleV Streptomyces antibioticus
5
 Q9L6C6_STRAT
(Q9L6C6)		 
[query] 16 - 473 (473)
[subject] 14 - 473 (474)
 1e-146 523   58% DTDP-4-keto-6-deoxyglucose 2,3-dehydratase Streptomyces antibioticus
6
 Q93F99_STRAT
(Q93F99)		 
[query] 12 - 472 (473)
[subject] 22 - 480 (482)
 1e-142 510   54% Sim20 sim20 Streptomyces antibioticus
7
 Q9AMH2_STRAT
(Q9AMH2)		 
[query] 12 - 472 (473)
[subject] 22 - 480 (482)
 1e-141 507   54% Putative dNDP-4-keto-6-deoxy-glucose-2,3-dehydratase SimB3 simB3 Streptomyces antibioticus
8
 O50540_SACER
(O50540)		 
[query] 26 - 468 (473)
[subject] 53 - 499 (510)
(3 hsp)		 1e-133 481   54% Putative 2,3 dehydratase EryBVI Saccharopolyspora erythraea
Streptomyces erythraeus
9
 A4F7N4_SACEN
(A4F7N4)		 
[query] 26 - 468 (473)
[subject] 30 - 476 (487)
(3 hsp)		 1e-133 480   54% NDP-4-keto-6-deoxy-glucose 2,3-dehydratase eryBVI
SACE_0717		 Saccharopolyspora erythraea (strain NRRL 23338)
10
 A8CAC1_9ACTO
(A8CAC1)		 
[query] 9 - 468 (473)
[subject] 326 - 781 (787)
(2 hsp)		 1e-133 480   55% NDP-hexose 2,3-dehydratase/thioesterase Streptomyces eurythermus
11
 O33941_SACER
(O33941)		 
[query] 26 - 468 (473)
[subject] 30 - 476 (487)
(3 hsp)		 1e-132 478   53% EryBVI eryBVI Saccharopolyspora erythraea
Streptomyces erythraeus
12
 A8Y8H1_STRAM
(A8Y8H1)		 
[query] 2 - 468 (473)
[subject] 4 - 463 (469)
(2 hsp)		 1e-131 472   55% Probable NDP-hexose dehydratase srm7 Streptomyces ambofaciens
13
 D6MSX2_9ACTO
(D6MSX2)		 
[query] 23 - 472 (473)
[subject] 17 - 465 (467)
 1e-129 467   52% SsfS3 ssfS3 Streptomyces sp. SF2575
14
 C0JWA9_9ACTO
(C0JWA9)		 Jump to Polk_00140 
[query] 11 - 473 (473)
[subject] 16 - 475 (476)
 1e-129 466   52% PokS3 pokS3 Streptomyces diastatochromogenes
15
 Q194Q2_STRAA
(Q194Q2)		 Jump to Mith_00230 
[query] 18 - 472 (473)
[subject] 30 - 484 (486)
 1e-129 466   53% D-olivose, D-oliose and D-mycarose 2,3-dehydratase mtmV Streptomyces argillaceus
16
 D9UBQ2_STRPR
(D9UBQ2)		 
[query] 29 - 467 (473)
[subject] 7 - 450 (467)
 1e-128 462   53% Putative NDP-hexose 2,3-dehydratase cpp32 Streptomyces pristinaespiralis
17
 B5HKI1_STRPR
(B5HKI1)		 
[query] 29 - 467 (473)
[subject] 7 - 450 (467)
 1e-128 462   53% NDP-hexose 2,3-dehydratase SSDG_05669 Streptomyces pristinaespiralis ATCC 25486
18
 B3TMP2_9ACTO
(B3TMP2)		 
[query] 9 - 473 (473)
[subject] 17 - 478 (479)
 1e-128 461   53% Sugar 2,3-dehydratase KijB1 Actinomadura kijaniata
19
 Q76KZ0_STRHA
(Q76KZ0)		 Jump to Vicen_00100 
[query] 2 - 473 (473)
[subject] 11 - 482 (489)
 1e-128 461   49% DTDP-4-keto-6-deoxyglucose 2,3-dehydratase vinD Streptomyces halstedii
20
 E9L1G4_9ZZZZ
(E9L1G4)		 
[query] 8 - 470 (473)
[subject] 26 - 482 (490)
(2 hsp)		 1e-125 454   52% Putative uncharacterized protein CA37-20 uncultured organism CA37
21
 D7BZT9_STRBB
(D7BZT9)		 
[query] 11 - 470 (473)
[subject] 22 - 466 (474)
 1e-125 452   52% NDP-hexose 23-dehydratase SBI_06874 Streptomyces bingchenggensis (strain BCW-1)
22
 Q2HR51_9ACTO
(Q2HR51)		 Jump to Sch475_00230 
[query] 16 - 473 (473)
[subject] 21 - 460 (465)
(2 hsp)		 1e-124 451   51% Putative NDP-hexose 2, 3-dehydratase schS2 Streptomyces sp. SCC 2136
23
 E9L1Q9_9ZZZZ
(E9L1Q9)		 
[query] 23 - 473 (473)
[subject] 34 - 478 (500)
(3 hsp)		 1e-124 449   52% Putative uncharacterized protein CA915-17 uncultured organism CA915
24
 Q9ZGC4_STRCY
(Q9ZGC4)		 Jump to Lando_00160 
[query] 23 - 472 (473)
[subject] 37 - 463 (469)
(2 hsp)		 1e-123 447   53% NDP-hexose 2,3-dehydratase homolog lanS Streptomyces cyanogenus
25
 D5UX43_TSUPD
(D5UX43)		 
[query] 53 - 473 (473)
[subject] 1 - 421 (435)
 1e-123 447   53% NDP-hexose 23-dehydratase Tpau_3481 Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040)
Corynebacterium paurometabolum
26
 F2RC29_STRVP
(F2RC29)		 
[query] 12 - 468 (473)
[subject] 23 - 462 (471)
(2 hsp)		 1e-123 445   50% 2,3-dehydratase SVEN_5994 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
27
 Q9ALN6_9PSEU
(Q9ALN6)		 Jump to Spino_00070 
[query] 9 - 473 (473)
[subject] 19 - 481 (486)
 1e-122 445   51% Probable NDP-hexose-2,3-dehydratase spnO Saccharopolyspora spinosa
28
 Q7WT23_9ACTO
(Q7WT23)		 Jump to Medem_00190 
[query] 12 - 472 (473)
[subject] 34 - 473 (479)
(2 hsp)		 1e-122 443   52% NDP-deoxyglucose-2,3-dehydratase med-ORF16 Streptomyces sp. AM-7161
29
 Q2J5G0_FRASC
(Q2J5G0)		 
[query] 27 - 470 (473)
[subject] 5 - 427 (437)
(2 hsp)		 1e-122 442   50% NDP-hexose 2,3-dehydratase Francci3_4134 Frankia sp. (strain CcI3)
30
 C4NYM3_9ACTO
(C4NYM3)		 
[query] 12 - 473 (473)
[subject] 26 - 464 (467)
 1e-121 439   52% SaqS saqS Micromonospora sp. Tu 6368
31
 Q9L4S4_STRFR
(Q9L4S4)		 Jump to Urd_00260 
[query] 12 - 473 (473)
[subject] 21 - 464 (469)
 1e-120 438   50% NDP-hexose 2,3-dehydratase UrdS urdS Streptomyces fradiae
Streptomyces roseoflavus
32
 B8Y4F2_STRAU
(B8Y4F2)		 
[query] 12 - 472 (473)
[subject] 22 - 460 (465)
(2 hsp)		 1e-120 437   51% Putative NDP-hexose 2,3-dehydratase aur1S Streptomyces aureofaciens
33
 Q4JHQ4_9PSEU
(Q4JHQ4)		 
[query] 30 - 473 (473)
[subject] 40 - 481 (486)
 1e-120 436   52% BusO busO Saccharopolyspora pogona
34
 Q9S0P1_STRAW
(Q9S0P1)		 Jump to Aver_00160 
[query] 26 - 468 (473)
[subject] 41 - 460 (469)
(3 hsp)		 1e-120 436   52% dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase aveBVI
SAV950
SAV_950		 Streptomyces avermitilis
35
 Q67G51_9ACTO
(Q67G51)		 Jump to Heda_00070 
[query] 8 - 473 (473)
[subject] 15 - 478 (480)
 1e-120 436   50% 2,3-hexose dehydratase Streptomyces griseoruber
36
 Q5Y9H9_9ACTO
(Q5Y9H9)		 
[query] 1 - 468 (473)
[subject] 1 - 467 (478)
(2 hsp)		 1e-119 434   49% Deoxyhexose dehydratase eryBVI Aeromicrobium erythreum
37
 O52793_AMYOR
(O52793)		 Jump to Chlor_00240 
[query] 7 - 472 (473)
[subject] 18 - 462 (471)
(2 hsp)		 1e-119 433   49% PCZA361.3 Amycolatopsis orientalis
Nocardia orientalis
38
 Q939X7_9PSEU
(Q939X7)		 Jump to Balhi_00280 
[query] 12 - 472 (473)
[subject] 14 - 461 (470)
(2 hsp)		 1e-119 432   48% Putative NDP-hexose 2,3-dehydratase dvaA Amycolatopsis balhimycina
39
 D7CFD0_STRBB
(D7CFD0)		 
[query] 16 - 470 (473)
[subject] 17 - 453 (460)
 1e-119 432   51% NDP-hexose 23-dehydratase SBI_01545 Streptomyces bingchenggensis (strain BCW-1)
40
 D8I4I8_AMYMU
(D8I4I8)		 
[query] 32 - 473 (473)
[subject] 37 - 472 (473)
 1e-118 431   52% NDP-hexose 23-dehydratase AMED_5402 Amycolatopsis mediterranei (strain U-32)
41
 E0KQN4_STRVO
(E0KQN4)		 
[query] 15 - 473 (473)
[subject] 11 - 456 (458)
 1e-118 431   49% NDP-hexose 23-dehydratase StrviDRAFT_4961 Streptomyces violaceusniger Tu 4113
42
 C4RP88_9ACTO
(C4RP88)		 
[query] 29 - 473 (473)
[subject] 30 - 468 (469)
 1e-118 430   53% 2,3-dehydratase MCAG_03651 Micromonospora sp. ATCC 39149
43
 B7T1A4_9BACT
(B7T1A4)		 
[query] 7 - 472 (473)
[subject] 17 - 462 (471)
(2 hsp)		 1e-118 429   48% Veg32 veg32 uncultured soil bacterium
44
 F8STZ2_AMYOR
(F8STZ2)		 
[query] 16 - 465 (473)
[subject] 24 - 452 (468)
 1e-117 426   49% NDP-hexose 2,3-dehydrolase vcm19 Amycolatopsis orientalis
Nocardia orientalis
45
 O54255_STRNO
(O54255)		 Jump to Nogl_00290 
[query] 28 - 470 (473)
[subject] 37 - 478 (488)
(2 hsp)		 1e-117 426   50% SnogH snogH Streptomyces nogalater
46
 D9WEH4_9ACTO
(D9WEH4)		 
[query] 8 - 473 (473)
[subject] 19 - 463 (464)
 1e-117 425   49% dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase SSOG_02927 Streptomyces himastatinicus ATCC 53653
47
 Q3S871_9ACTO
(Q3S871)		 Jump to Conca_00190 
[query] 15 - 473 (473)
[subject] 25 - 484 (500)
(2 hsp)		 1e-116 424   50% 2,3-dehydratase Streptomyces neyagawaensis
48
 E9L1N4_9ZZZZ
(E9L1N4)		 
[query] 12 - 472 (473)
[subject] 28 - 467 (476)
(2 hsp)		 1e-116 423   48% Putative uncharacterized protein CA878-35 uncultured organism CA878
49
 C9YYJ0_STRSW
(C9YYJ0)		 
[query] 15 - 473 (473)
[subject] 25 - 484 (500)
(2 hsp)		 1e-116 423   49% Putative NDP-hexose 2,3-dehydratase SCAB_83991 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
50
 Q9JN57_STRFR
(Q9JN57)		 
[query] 43 - 468 (473)
[subject] 19 - 449 (455)
(2 hsp)		 1e-116 422   53% TylCVI tylCVI Streptomyces fradiae
Streptomyces roseoflavus
51
 D1GLT9_9ACTO
(D1GLT9)		 Jump to Strply_00110 
[query] 30 - 473 (473)
[subject] 13 - 449 (450)
(2 hsp)		 1e-115 421   51% NDP-hexose-2,3-dehydratase slgS3 Streptomyces lydicus
52
 Q9REU2_STRFR
(Q9REU2)		 
[query] 8 - 468 (473)
[subject] 5 - 472 (478)
(2 hsp)		 1e-115 421   50% TDP-6-deoxy-4-ketohexose 2,3-dehydratase tylCVI Streptomyces fradiae
Streptomyces roseoflavus
53
 Q0R4N9_STRAT
(Q0R4N9)		 Jump to Chth_00150 
[query] 30 - 473 (473)
[subject] 10 - 437 (438)
 1e-115 419   52% ChlC3 Streptomyces antibioticus
54
 E3T4A5_9ACTO
(E3T4A5)		 
[query] 28 - 473 (473)
[subject] 8 - 442 (449)
 1e-115 419   50% dTDP-4-keto-6-deoxyglucose 2,3-dehydratase gra-orf27 Streptomyces vietnamensis
55
 D1A611_THECD
(D1A611)		 
[query] 25 - 473 (473)
[subject] 27 - 465 (466)
(2 hsp)		 1e-114 418   50% NDP-hexose 23-dehydratase Tcur_2760 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
56
 D6AT93_STRFL
(D6AT93)		 
[query] 9 - 472 (473)
[subject] 8 - 448 (454)
 1e-114 417   49% NDP-hexose 2,3-dehydratase UrdS SSGG_05537 Streptomyces roseosporus NRRL 15998
57
 Q2PC37_STRAH
(Q2PC37)		 Jump to Rubra_00530 
[query] 18 - 468 (473)
[subject] 25 - 449 (458)
(2 hsp)		 1e-114 416   51% Putative TDP-glucose-2,3-dehydratase rubN3 Streptomyces achromogenes subsp. rubradiris
58
 B5L6M2_MICCH
(B5L6M2)		 
[query] 5 - 473 (473)
[subject] 13 - 486 (487)
 1e-114 416   47% 2,3-hexose dehydratase Micromonospora chalcea
59
 Q9ZA32_STRVN
(Q9ZA32)		 Jump to Grana_00210 
[query] 24 - 473 (473)
[subject] 3 - 436 (443)
 1e-114 416   49% Putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase gra-orf27 Streptomyces violaceoruber
60
 E5RLM8_9ACTO
(E5RLM8)		 
[query] 11 - 473 (473)
[subject] 28 - 492 (497)
 1e-114 416   47% Putative NDP-hexose 2,3-dehydratase pnxS3 Streptomyces sp. TA-0256
61
 B0LJ28_9ACTO
(B0LJ28)		 
[query] 3 - 472 (473)
[subject] 13 - 462 (468)
(2 hsp)		 1e-113 414   49% Lct45 lct45 Streptomyces rishiriensis
62
 Q0H2W5_9ACTO
(Q0H2W5)		 
[query] 29 - 473 (473)
[subject] 48 - 482 (483)
 1e-113 413   50% Probable NDP-hexose-2,3-dehydratase atS14 Actinomadura melliaura
63
 D9T284_MICAI
(D9T284)		 
[query] 12 - 473 (473)
[subject] 20 - 476 (478)
 1e-113 413   48% NDP-hexose 23-dehydratase Micau_3987 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
64
 E8RWU5_MICSL
(E8RWU5)		 
[query] 12 - 473 (473)
[subject] 20 - 476 (478)
 1e-113 412   48% NDP-hexose 23-dehydratase ML5_4434 Micromonospora sp. (strain L5)
65
 Q845B8_STRAH
(Q845B8)		 
[query] 18 - 468 (473)
[subject] 25 - 449 (458)
(2 hsp)		 1e-112 411   51% DTDP-glucose-2,3-dehydratase rub52 Streptomyces achromogenes
66
 Q83WG1_9ACTO
(Q83WG1)		 
[query] 16 - 472 (473)
[subject] 27 - 463 (472)
(2 hsp)		 1e-112 411   49% 2,3-dehydratase staJ Streptomyces sp. TP-A0274
67
 D6AXN3_9ACTO
(D6AXN3)		 
[query] 10 - 472 (473)
[subject] 18 - 460 (462)
 1e-112 410   47% AclN SSHG_05325 Streptomyces albus J1074
68
 Q30CR3_STRAU
(Q30CR3)		 Jump to Alip_00220 
[query] 37 - 472 (473)
[subject] 69 - 481 (486)
 1e-112 409   50% LipDig5 lipDig5 Streptomyces aureofaciens
69
 D7RFL3_AMYOR
(D7RFL3)		 
[query] 33 - 470 (473)
[subject] 12 - 422 (439)
(3 hsp)		 1e-111 407   48% Putative sugar 2,3-dehydratase bexV Amycolatopsis orientalis subsp. vinearia
70
 Q8KNC9_MICEC
(Q8KNC9)		 Jump to Calm_00680 
[query] 26 - 473 (473)
[subject] 34 - 475 (476)
 1e-111 406   48% CalS14 calS14 Micromonospora echinospora
Micromonospora purpurea
71
 D3CRC6_9ACTO
(D3CRC6)		 
[query] 18 - 473 (473)
[subject] 26 - 482 (489)
(2 hsp)		 1e-111 406   48% NDP-hexose 23-dehydratase FrEUN1fDRAFT_0124 Frankia sp. EUN1f
72
 A8M282_SALAI
(A8M282)		 
[query] 12 - 472 (473)
[subject] 18 - 456 (465)
(2 hsp)		 1e-110 404   49% NDP-hexose 23-dehydratase Sare_2340 Salinispora arenicola (strain CNS-205)
73
 B5G893_9ACTO
(B5G893)		 
[query] 10 - 472 (473)
[subject] 5 - 442 (448)
 1e-110 404   48% dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase SSBG_00501 Streptomyces sp. SPB74
74
 A8LZN2_SALAI
(A8LZN2)		 
[query] 27 - 473 (473)
[subject] 35 - 473 (474)
 1e-110 403   48% NDP-hexose 23-dehydratase Sare_2025 Salinispora arenicola (strain CNS-205)
75
 Q2I757_9ACTO
(Q2I757)		 
[query] 18 - 473 (473)
[subject] 28 - 459 (463)
 1e-109 400   47% PlaA2 plaA2
STTU_1456		 Streptomyces sp. Tu6071
76
 P95833_STRPE
(P95833)		 Jump to Adria_00060 
[query] 10 - 473 (473)
[subject] 2 - 487 (505)
 1e-109 400   44% Doxorubicin biosynthesis protein DnmT dnmT Streptomyces peucetius
77
 Q83X51_STRRO
(Q83X51)		 
[query] 9 - 470 (473)
[subject] 19 - 478 (483)
 1e-109 399   48% Putative NDP-4-keto-6-deoxyhexose 2,3-dehydratase lkmBVI Streptomyces rochei
Streptomyces parvullus
78
 E5DUG9_9NOCA
(E5DUG9)		 
[query] 29 - 470 (473)
[subject] 26 - 470 (476)
(2 hsp)		 1e-109 399   47% NocS5 nocS5 Nocardia sp. ATCC 202099
79
 Q64Y66_BACFR
(Q64Y66)		 
[query] 23 - 470 (473)
[subject] 12 - 455 (460)
(2 hsp)		 1e-108 398   43% Putative dNDP-4-keto-6-deoxy-glucose-2,3-dehydratase BF0809 Bacteroides fragilis
80
 C7MX48_SACVD
(C7MX48)		 
[query] 28 - 473 (473)
[subject] 32 - 475 (478)
 1e-106 391   48% NDP-hexose 2,3-dehydratase Svir_29870 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
81
 A4X6Y2_SALTO
(A4X6Y2)		 
[query] 10 - 472 (473)
[subject] 16 - 454 (477)
 1e-106 390   48% NDP-hexose 2,3-dehydratase Strop_2181 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
82
 E2NJ87_9BACE
(E2NJ87)		 
[query] 15 - 470 (473)
[subject] 4 - 455 (459)
 1e-106 390   43% Putative uncharacterized protein BACCELL_04373 Bacteroides cellulosilyticus DSM 14838
83
 D7B006_NOCDD
(D7B006)		 
[query] 9 - 473 (473)
[subject] 6 - 457 (458)
 1e-105 388   49% NDP-hexose 23-dehydratase Ndas_4708 Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
84
 Q70J94_STRGR
(Q70J94)		 Jump to Chro_00040 
[query] 5 - 473 (473)
[subject] 13 - 450 (460)
 1e-105 386   46% NDP-2,3-dehydratase cmmV Streptomyces griseus subsp. griseus
85
 Q9AL96_9ACTO
(Q9AL96)		 Jump to Jado_00210 
[query] 12 - 468 (473)
[subject] 20 - 465 (474)
 1e-104 382   45% NDP-hexose 2,3-dehydratase jadO Streptomyces venezuelae
86
 C6BTH7_DESAD
(C6BTH7)		 
[query] 18 - 470 (473)
[subject] 16 - 472 (475)
(2 hsp)		 1e-103 380   42% NDP-hexose 23-dehydratase Desal_3612 Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763)
87
 C6Z1M2_9BACE
(C6Z1M2)		 
[query] 18 - 473 (473)
[subject] 12 - 472 (473)
 1e-102 377   40% NDP-hexose 2,3-dehydratase BSFG_00928 Bacteroides sp. 4_3_47FAA
88
 A0M305_GRAFK
(A0M305)		 
[query] 21 - 470 (473)
[subject] 17 - 468 (473)
 1e-102 376   39% NDP-hexose 2,3-dehydratase GFO_2035 Gramella forsetii (strain KT0803)
89
 Q8VWC0_9ACTO
(Q8VWC0)		 
[query] 10 - 473 (473)
[subject] 5 - 443 (450)
 1e-101 372   46% AclN aclN Streptomyces galilaeus
90
 D2L2F5_9DELT
(D2L2F5)		 
[query] 15 - 470 (473)
[subject] 12 - 466 (473)
 2e-99 368   45% NDP-hexose 23-dehydratase DFW101DRAFT_0868 Desulfovibrio sp. FW1012B
91
 D5SL06_STRCL
(D5SL06)		 
[query] 16 - 472 (473)
[subject] 40 - 539 (552)
 2e-95 354   42% Staurosporine biosynthesis 2,3-dehydratase StaJ staJ
SCLAV_p1113		 Streptomyces clavuligerus ATCC 27064
92
 E1K295_DESFR
(E1K295)		 
[query] 27 - 470 (473)
[subject] 24 - 466 (473)
(2 hsp)		 3e-95 353   43% NDP-hexose 23-dehydratase DesfrDRAFT_3995 Desulfovibrio fructosovorans JJ
93
 B5H2L9_STRCL
(B5H2L9)		 
[query] 16 - 472 (473)
[subject] 16 - 515 (528)
 3e-95 353   42% 2,3-dehydratase SSCG_05826 Streptomyces clavuligerus ATCC 27064
94
 C4XJ85_DESMR
(C4XJ85)		 
[query] 15 - 470 (473)
[subject] 12 - 465 (472)
 5e-95 353   44% NDP-hexose 2,3-dehydratase DMR_07580 Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)
95
 C7G1S5_STRGR
(C7G1S5)		 
[query] 29 - 470 (473)
[subject] 25 - 464 (465)
(2 hsp)		 3e-93 347   44% Putative 2,3-dehydratase Streptomyces griseus
96
 Q53880_STRS5
(Q53880)		 Jump to Dauno_00040 
[query] 3 - 473 (473)
[subject] 4 - 497 (516)
 1e-92 345   40% Putative uncharacterized protein Streptomyces sp. (strain C5)
97
 E1CG34_9ACTO
(E1CG34)		 
[query] 29 - 470 (473)
[subject] 31 - 466 (467)
(2 hsp)		 2e-91 341   43% Putative NDP-hexose 2,3-dehydratase capE Streptomyces sp. SANK 62799
98
 B1VRP4_STRGG
(B1VRP4)		 
[query] 33 - 468 (473)
[subject] 18 - 430 (439)
(2 hsp)		 1e-90 338   47% Putative NDP-deoxyglucose-2,3-dehydratase SGR_633 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
99
 D9VC38_9ACTO
(D9VC38)		 
[query] 21 - 470 (473)
[subject] 14 - 449 (459)
(3 hsp)		 1e-87 328   43% Predicted protein SSMG_03426 Streptomyces sp. AA4
100
 Q0PY18_STRMY
(Q0PY18)		 
[query] 55 - 409 (473)
[subject] 5 - 349 (372)
(3 hsp)		 4e-84 317   53% DTDP-4-keto-6-deoxyglucose 2,3-dehydratase midL Streptomyces mycarofaciens
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 D8HZB0_AMYMU
(D8HZB0)		 
[query] 1 - 473 (473)
[subject] 1 - 473 (473)
 0.0 972   100%
Product
NDP-hexose 2,3-dehydratase
Gene
AMED_0645
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
2
 Q9AE03_AMYMD
(Q9AE03)		 
[query] 1 - 473 (473)
[subject] 1 - 473 (473)
 0.0 972   100%
Product
Putative 2,3-dehydratase
Gene
 
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
4
 Q9RR31_STRAT
(Q9RR31)		 
[query] 16 - 473 (473)
[subject] 14 - 473 (474)
 1e-147 528   59%
Product
2,3-dehydratase
Gene
oleV
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10770761 [Medline] 20233594
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.(Antimicrob. Agents Chemother.) [2000]
5
 Q9L6C6_STRAT
(Q9L6C6)		 
[query] 16 - 473 (473)
[subject] 14 - 473 (474)
 1e-146 523   58%
Product
DTDP-4-keto-6-deoxyglucose 2,3-dehydratase
Gene
 
Organism
Streptomyces antibioticus
1uniprot
Mechanism of the 2-deoxygenation step in the biosynthesis of the deoxyhexose moieties of the antibiotics granaticin and oleandomycin.(J. Am. Chem. Soc.) [1999]
6
 Q93F99_STRAT
(Q93F99)		 
[query] 12 - 472 (473)
[subject] 22 - 480 (482)
 1e-142 510   54%
Product
Sim20
Gene
sim20
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
7
 Q9AMH2_STRAT
(Q9AMH2)		 
[query] 12 - 472 (473)
[subject] 22 - 480 (482)
 1e-141 507   54%
Product
Putative dNDP-4-keto-6-deoxy-glucose-2,3-dehydratase SimB3
Gene
simB3
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
8
 O50540_SACER
(O50540)		 
[query] 26 - 468 (473)
[subject] 53 - 499 (510)
(3 hsp)		 1e-133 481   54%
Product
Putative 2,3 dehydratase
Gene
EryBVI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 9393448 [Medline] 98055166
Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.(Mol. Gen. Genet.) [1997]
9
 A4F7N4_SACEN
(A4F7N4)		 
[query] 26 - 468 (473)
[subject] 30 - 476 (487)
(3 hsp)		 1e-133 480   54%
Product
NDP-4-keto-6-deoxy-glucose 2,3-dehydratase
Gene
eryBVI
SACE_0717
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
11
 O33941_SACER
(O33941)		 
[query] 26 - 468 (473)
[subject] 30 - 476 (487)
(3 hsp)		 1e-132 478   53%
Product
EryBVI
Gene
eryBVI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 9353926 [Medline] 98015410
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.(Microbiology)
12
 A8Y8H1_STRAM
(A8Y8H1)		 
[query] 2 - 468 (473)
[subject] 4 - 463 (469)
(2 hsp)		 1e-131 472   55%
Product
Probable NDP-hexose dehydratase
Gene
srm7
Organism
Streptomyces ambofaciens
1uniprot
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
13
 D6MSX2_9ACTO
(D6MSX2)		 
[query] 23 - 472 (473)
[subject] 17 - 465 (467)
 1e-129 467   52%
Product
SsfS3
Gene
ssfS3
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
14
 C0JWA9_9ACTO
(C0JWA9)		 Jump to Polk_00140 
[query] 11 - 473 (473)
[subject] 16 - 475 (476)
 1e-129 466   52%
Product
PokS3
Gene
pokS3
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
15
 Q194Q2_STRAA
(Q194Q2)		 Jump to Mith_00230 
[query] 18 - 472 (473)
[subject] 30 - 484 (486)
 1e-129 466   53%
Product
D-olivose, D-oliose and D-mycarose 2,3-dehydratase
Gene
mtmV
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
16
 D9UBQ2_STRPR
(D9UBQ2)		 
[query] 29 - 467 (473)
[subject] 7 - 450 (467)
 1e-128 462   53%
Product
Putative NDP-hexose 2,3-dehydratase
Gene
cpp32
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
18
 B3TMP2_9ACTO
(B3TMP2)		 
[query] 9 - 473 (473)
[subject] 17 - 478 (479)
 1e-128 461   53%
Product
Sugar 2,3-dehydratase
Gene
KijB1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
19
 Q76KZ0_STRHA
(Q76KZ0)		 Jump to Vicen_00100 
[query] 2 - 473 (473)
[subject] 11 - 482 (489)
 1e-128 461   49%
Product
DTDP-4-keto-6-deoxyglucose 2,3-dehydratase
Gene
vinD
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
20
 E9L1G4_9ZZZZ
(E9L1G4)		 
[query] 8 - 470 (473)
[subject] 26 - 482 (490)
(2 hsp)		 1e-125 454   52%
Product
Putative uncharacterized protein
Gene
CA37-20
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
21
 D7BZT9_STRBB
(D7BZT9)		 
[query] 11 - 470 (473)
[subject] 22 - 466 (474)
 1e-125 452   52%
Product
NDP-hexose 23-dehydratase
Gene
SBI_06874
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
22
 Q2HR51_9ACTO
(Q2HR51)		 Jump to Sch475_00230 
[query] 16 - 473 (473)
[subject] 21 - 460 (465)
(2 hsp)		 1e-124 451   51%
Product
Putative NDP-hexose 2, 3-dehydratase
Gene
schS2
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
23
 E9L1Q9_9ZZZZ
(E9L1Q9)		 
[query] 23 - 473 (473)
[subject] 34 - 478 (500)
(3 hsp)		 1e-124 449   52%
Product
Putative uncharacterized protein
Gene
CA915-17
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
24
 Q9ZGC4_STRCY
(Q9ZGC4)		 Jump to Lando_00160 
[query] 23 - 472 (473)
[subject] 37 - 463 (469)
(2 hsp)		 1e-123 447   53%
Product
NDP-hexose 2,3-dehydratase homolog
Gene
lanS
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
26
 F2RC29_STRVP
(F2RC29)		 
[query] 12 - 468 (473)
[subject] 23 - 462 (471)
(2 hsp)		 1e-123 445   50%
Product
2,3-dehydratase
Gene
SVEN_5994
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
27
 Q9ALN6_9PSEU
(Q9ALN6)		 Jump to Spino_00070 
[query] 9 - 473 (473)
[subject] 19 - 481 (486)
 1e-122 445   51%
Product
Probable NDP-hexose-2,3-dehydratase
Gene
spnO
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
28
 Q7WT23_9ACTO
(Q7WT23)		 Jump to Medem_00190 
[query] 12 - 472 (473)
[subject] 34 - 473 (479)
(2 hsp)		 1e-122 443   52%
Product
NDP-deoxyglucose-2,3-dehydratase
Gene
med-ORF16
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
29
 Q2J5G0_FRASC
(Q2J5G0)		 
[query] 27 - 470 (473)
[subject] 5 - 427 (437)
(2 hsp)		 1e-122 442   50%
Product
NDP-hexose 2,3-dehydratase
Gene
Francci3_4134
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
30
 C4NYM3_9ACTO
(C4NYM3)		 
[query] 12 - 473 (473)
[subject] 26 - 464 (467)
 1e-121 439   52%
Product
SaqS
Gene
saqS
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
31
 Q9L4S4_STRFR
(Q9L4S4)		 Jump to Urd_00260 
[query] 12 - 473 (473)
[subject] 21 - 464 (469)
 1e-120 438   50%
Product
NDP-hexose 2,3-dehydratase UrdS
Gene
urdS
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 11094336 [Medline] 20547803
The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster.(Chem. Biol.) [2000]
32
 B8Y4F2_STRAU
(B8Y4F2)		 
[query] 12 - 472 (473)
[subject] 22 - 460 (465)
(2 hsp)		 1e-120 437   51%
Product
Putative NDP-hexose 2,3-dehydratase
Gene
aur1S
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 20490753
Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.(Folia Microbiol. (Praha)) [2010]
33
 Q4JHQ4_9PSEU
(Q4JHQ4)		 
[query] 30 - 473 (473)
[subject] 40 - 481 (486)
 1e-120 436   52%
Product
BusO
Gene
busO
Organism
Saccharopolyspora pogona
1uniprot[Pubmed] 16179985
Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
34
 Q9S0P1_STRAW
(Q9S0P1)		 Jump to Aver_00160 
[query] 26 - 468 (473)
[subject] 41 - 460 (469)
(3 hsp)		 1e-120 436   52%
Product
dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase
Gene
aveBVI
SAV950
SAV_950
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
35
 Q67G51_9ACTO
(Q67G51)		 Jump to Heda_00070 
[query] 8 - 473 (473)
[subject] 15 - 478 (480)
 1e-120 436   50%
Product
2,3-hexose dehydratase
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
36
 Q5Y9H9_9ACTO
(Q5Y9H9)		 
[query] 1 - 468 (473)
[subject] 1 - 467 (478)
(2 hsp)		 1e-119 434   49%
Product
Deoxyhexose dehydratase
Gene
eryBVI
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
37
 O52793_AMYOR
(O52793)		 Jump to Chlor_00240 
[query] 7 - 472 (473)
[subject] 18 - 462 (471)
(2 hsp)		 1e-119 433   49%
Product
PCZA361.3
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]
38
 Q939X7_9PSEU
(Q939X7)		 Jump to Balhi_00280 
[query] 12 - 472 (473)
[subject] 14 - 461 (470)
(2 hsp)		 1e-119 432   48%
Product
Putative NDP-hexose 2,3-dehydratase
Gene
dvaA
Organism
Amycolatopsis balhimycina
1uniprot[Pubmed] 10390204 [Medline] 99318579
Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385
The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276
Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot
Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]
[pubmed all]
39
 D7CFD0_STRBB
(D7CFD0)		 
[query] 16 - 470 (473)
[subject] 17 - 453 (460)
 1e-119 432   51%
Product
NDP-hexose 23-dehydratase
Gene
SBI_01545
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
40
 D8I4I8_AMYMU
(D8I4I8)		 
[query] 32 - 473 (473)
[subject] 37 - 472 (473)
 1e-118 431   52%
Product
NDP-hexose 23-dehydratase
Gene
AMED_5402
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
43
 B7T1A4_9BACT
(B7T1A4)		 
[query] 7 - 472 (473)
[subject] 17 - 462 (471)
(2 hsp)		 1e-118 429   48%
Product
Veg32
Gene
veg32
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
45
 O54255_STRNO
(O54255)		 Jump to Nogl_00290 
[query] 28 - 470 (473)
[subject] 37 - 478 (488)
(2 hsp)		 1e-117 426   50%
Product
SnogH
Gene
snogH
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
47
 Q3S871_9ACTO
(Q3S871)		 Jump to Conca_00190 
[query] 15 - 473 (473)
[subject] 25 - 484 (500)
(2 hsp)		 1e-116 424   50%
Product
2,3-dehydratase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
48
 E9L1N4_9ZZZZ
(E9L1N4)		 
[query] 12 - 472 (473)
[subject] 28 - 467 (476)
(2 hsp)		 1e-116 423   48%
Product
Putative uncharacterized protein
Gene
CA878-35
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
49
 C9YYJ0_STRSW
(C9YYJ0)		 
[query] 15 - 473 (473)
[subject] 25 - 484 (500)
(2 hsp)		 1e-116 423   49%
Product
Putative NDP-hexose 2,3-dehydratase
Gene
SCAB_83991
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
50
 Q9JN57_STRFR
(Q9JN57)		 
[query] 43 - 468 (473)
[subject] 19 - 449 (455)
(2 hsp)		 1e-116 422   53%
Product
TylCVI
Gene
tylCVI
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7984112 [Medline] 95075319
Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome.(Mol. Microbiol.) [1994]
2uniprot[Pubmed] 10467127 [Medline] 99398833
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae.(Chem. Biol.) [1999]
3uniprot[Pubmed] 10658660 [Medline] 20121747
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.(Microbiology) [2000]
[pubmed all]
51
 D1GLT9_9ACTO
(D1GLT9)		 Jump to Strply_00110 
[query] 30 - 473 (473)
[subject] 13 - 449 (450)
(2 hsp)		 1e-115 421   51%
Product
NDP-hexose-2,3-dehydratase
Gene
slgS3
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
53
 Q0R4N9_STRAT
(Q0R4N9)		 Jump to Chth_00150 
[query] 30 - 473 (473)
[subject] 10 - 437 (438)
 1e-115 419   52%
Product
ChlC3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
55
 D1A611_THECD
(D1A611)		 
[query] 25 - 473 (473)
[subject] 27 - 465 (466)
(2 hsp)		 1e-114 418   50%
Product
NDP-hexose 23-dehydratase
Gene
Tcur_2760
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
57
 Q2PC37_STRAH
(Q2PC37)		 Jump to Rubra_00530 
[query] 18 - 468 (473)
[subject] 25 - 449 (458)
(2 hsp)		 1e-114 416   51%
Product
Putative TDP-glucose-2,3-dehydratase
Gene
rubN3
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
58
 B5L6M2_MICCH
(B5L6M2)		 
[query] 5 - 473 (473)
[subject] 13 - 486 (487)
 1e-114 416   47%
Product
2,3-hexose dehydratase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
59
 Q9ZA32_STRVN
(Q9ZA32)		 Jump to Grana_00210 
[query] 24 - 473 (473)
[subject] 3 - 436 (443)
 1e-114 416   49%
Product
Putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase
Gene
gra-orf27
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
61
 B0LJ28_9ACTO
(B0LJ28)		 
[query] 3 - 472 (473)
[subject] 13 - 462 (468)
(2 hsp)		 1e-113 414   49%
Product
Lct45
Gene
lct45
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
62
 Q0H2W5_9ACTO
(Q0H2W5)		 
[query] 29 - 473 (473)
[subject] 48 - 482 (483)
 1e-113 413   50%
Product
Probable NDP-hexose-2,3-dehydratase
Gene
atS14
Organism
Actinomadura melliaura
1uniprot[Pubmed] 16873021
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]
65
 Q845B8_STRAH
(Q845B8)		 
[query] 18 - 468 (473)
[subject] 25 - 449 (458)
(2 hsp)		 1e-112 411   51%
Product
DTDP-glucose-2,3-dehydratase
Gene
rub52
Organism
Streptomyces achromogenes
1uniprot
Biosynthesis of Rubranitrose from the Rubradirin Producer, Streptomyces achromogenes var rubradiris NRRL 3061. [2002]
66
 Q83WG1_9ACTO
(Q83WG1)		 
[query] 16 - 472 (473)
[subject] 27 - 463 (472)
(2 hsp)		 1e-112 411   49%
Product
2,3-dehydratase
Gene
staJ
Organism
Streptomyces sp. TP-A0274
1uniprot
Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006]
2uniprot
Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006]
3uniprot[Pubmed] 12617516 [Medline] 22504382
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002]
4uniprot
Characterization of the biosynthetic gene cluster of rebecamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003]
5uniprot[Pubmed] 16195595
Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.(Biosci. Biotechnol. Biochem.) [2005]
[pubmed all]
68
 Q30CR3_STRAU
(Q30CR3)		 Jump to Alip_00220 
[query] 37 - 472 (473)
[subject] 69 - 481 (486)
 1e-112 409   50%
Product
LipDig5
Gene
lipDig5
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
69
 D7RFL3_AMYOR
(D7RFL3)		 
[query] 33 - 470 (473)
[subject] 12 - 422 (439)
(3 hsp)		 1e-111 407   48%
Product
Putative sugar 2,3-dehydratase
Gene
bexV
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
70
 Q8KNC9_MICEC
(Q8KNC9)		 Jump to Calm_00680 
[query] 26 - 473 (473)
[subject] 34 - 475 (476)
 1e-111 406   48%
Product
CalS14
Gene
calS14
Organism
Micromonospora echinospora
Micromonospora purpurea
1uniprot[Pubmed] 12183629 [Medline] 22171414
The calicheamicin gene cluster and its iterative type I enediyne PKS.(Science) [2002]
75
 Q2I757_9ACTO
(Q2I757)		 
[query] 18 - 473 (473)
[subject] 28 - 459 (463)
 1e-109 400   47%
Product
PlaA2
Gene
plaA2
STTU_1456
Organism
Streptomyces sp. Tu6071
1uniprot[Pubmed] 16632249
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives.(Chem. Biol.) [2006]
76
 P95833_STRPE
(P95833)		 Jump to Adria_00060 
[query] 10 - 473 (473)
[subject] 2 - 487 (505)
 1e-109 400   44%
Product
Doxorubicin biosynthesis protein DnmT
Gene
dnmT
Organism
Streptomyces peucetius
1uniprot[Pubmed] 8955419 [Medline] 97113559
Enhanced antibiotic production by manipulation of the Streptomyces peucetius dnrH and dnmT genes involved in doxorubicin (adriamycin) biosynthesis.(J. Bacteriol.) [1996]
2uniprot[Pubmed] 9864344 [Medline] 99084971
Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene.(J. Bacteriol.) [1999]
[pubmed all]
77
 Q83X51_STRRO
(Q83X51)		 
[query] 9 - 470 (473)
[subject] 19 - 478 (483)
 1e-109 399   48%
Product
Putative NDP-4-keto-6-deoxyhexose 2,3-dehydratase
Gene
lkmBVI
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
78
 E5DUG9_9NOCA
(E5DUG9)		 
[query] 29 - 470 (473)
[subject] 26 - 470 (476)
(2 hsp)		 1e-109 399   47%
Product
NocS5
Gene
nocS5
Organism
Nocardia sp. ATCC 202099
1uniprot[Pubmed] 20473441
Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099.(Mol. Biosyst.) [2010]
79
 Q64Y66_BACFR
(Q64Y66)		 
[query] 23 - 470 (473)
[subject] 12 - 455 (460)
(2 hsp)		 1e-108 398   43%
Product
Putative dNDP-4-keto-6-deoxy-glucose-2,3-dehydratase
Gene
BF0809
Organism
Bacteroides fragilis
1uniprot[Pubmed] 15466707
Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
80
 C7MX48_SACVD
(C7MX48)		 
[query] 28 - 473 (473)
[subject] 32 - 475 (478)
 1e-106 391   48%
Product
NDP-hexose 2,3-dehydratase
Gene
Svir_29870
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
83
 D7B006_NOCDD
(D7B006)		 
[query] 9 - 473 (473)
[subject] 6 - 457 (458)
 1e-105 388   49%
Product
NDP-hexose 23-dehydratase
Gene
Ndas_4708
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
85
 Q9AL96_9ACTO
(Q9AL96)		 Jump to Jado_00210 
[query] 12 - 468 (473)
[subject] 20 - 465 (474)
 1e-104 382   45%
Product
NDP-hexose 2,3-dehydratase
Gene
jadO
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 11932454 [Medline] 21930291
Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone.(Microbiology) [2002]
88
 A0M305_GRAFK
(A0M305)		 
[query] 21 - 470 (473)
[subject] 17 - 468 (473)
 1e-102 376   39%
Product
NDP-hexose 2,3-dehydratase
Gene
GFO_2035
Organism
Gramella forsetii (strain KT0803)
1uniprot[Pubmed] 17107561
Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter.(Environ. Microbiol.) [2006]
89
 Q8VWC0_9ACTO
(Q8VWC0)		 
[query] 10 - 473 (473)
[subject] 5 - 443 (450)
 1e-101 372   46%
Product
AclN
Gene
aclN
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
91
 D5SL06_STRCL
(D5SL06)		 
[query] 16 - 472 (473)
[subject] 40 - 539 (552)
 2e-95 354   42%
Product
Staurosporine biosynthesis 2,3-dehydratase StaJ
Gene
staJ
SCLAV_p1113
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
94
 C4XJ85_DESMR
(C4XJ85)		 
[query] 15 - 470 (473)
[subject] 12 - 465 (472)
 5e-95 353   44%
Product
NDP-hexose 2,3-dehydratase
Gene
DMR_07580
Organism
Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)
1uniprot[Pubmed] 19675025
Whole genome sequence of Desulfovibrio magneticus strain RS-1 revealed common gene clusters in magnetotactic bacteria.(Genome Res.) [2009]
95
 C7G1S5_STRGR
(C7G1S5)		 
[query] 29 - 470 (473)
[subject] 25 - 464 (465)
(2 hsp)		 3e-93 347   44%
Product
Putative 2,3-dehydratase
Gene
 
Organism
Streptomyces griseus
1uniprot
Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196.(J. Antibiot.) [2009]
96
 Q53880_STRS5
(Q53880)		 Jump to Dauno_00040 
[query] 3 - 473 (473)
[subject] 4 - 497 (516)
 1e-92 345   40%
Product
Putative uncharacterized protein
Gene
 
Organism
Streptomyces sp. (strain C5)
1uniprot[Pubmed] 8655529 [Medline] 96236066
Cloning, sequencing, and analysis of aklaviketone reductase from Streptomyces sp. strain C5.(J. Bacteriol.) [1996]
98
 B1VRP4_STRGG
(B1VRP4)		 
[query] 33 - 468 (473)
[subject] 18 - 430 (439)
(2 hsp)		 1e-90 338   47%
Product
Putative NDP-deoxyglucose-2,3-dehydratase
Gene
SGR_633
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
100
 Q0PY18_STRMY
(Q0PY18)		 
[query] 55 - 409 (473)
[subject] 5 - 349 (372)
(3 hsp)		 4e-84 317   53%
Product
DTDP-4-keto-6-deoxyglucose 2,3-dehydratase
Gene
midL
Organism
Streptomyces mycarofaciens
1uniprot[Pubmed] 17342257
Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from a midecamycin-producing strain, Streptomyces mycarofaciens.(Acta Biochim. Biophys. Sin.) [2007]